(2-(trimethylammonium)ethyl)methanethiosulfonate and lidocaine

(2-(trimethylammonium)ethyl)methanethiosulfonate has been researched along with lidocaine in 2 studies

Compound Research Comparison

Studies ((2-(trimethylammonium)ethyl)methanethiosulfonate)	Trials ((2-(trimethylammonium)ethyl)methanethiosulfonate)	Recent Studies (post-2010) ((2-(trimethylammonium)ethyl)methanethiosulfonate)	Studies (lidocaine)	Trials (lidocaine)	Recent Studies (post-2010) (lidocaine)
143	0	17	26,090	5,904	5,591

Protein Interaction Comparison

Protein	Taxonomy	(2-(trimethylammonium)ethyl)methanethiosulfonate (IC50)	lidocaine (IC50)
Sodium channel protein type 4 subunit alpha	Homo sapiens (human)		2

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Fozzard, HA; Glaaser, IW; Sunami, A	1
Chen, T; Hanck, DA; Sheets, MF	1

Other Studies

2 other study(ies) available for (2-(trimethylammonium)ethyl)methanethiosulfonate and lidocaine

Article	Year
Structural and gating changes of the sodium channel induced by mutation of a residue in the upper third of IVS6, creating an external access path for local anesthetics. Molecular pharmacology, 2001, Volume: 59, Issue:4 Topics: Amino Acid Substitution; Anesthetics, Local; Animals; Calcium Channel Blockers; Cells, Cultured; Conotoxins; Ethyl Methanesulfonate; Ion Channel Gating; Lidocaine; Mesylates; Mutagenesis, Site-Directed; Oocytes; Patch-Clamp Techniques; Protein Isoforms; Rats; Saxitoxin; Sodium Channel Blockers; Sodium Channels; Structure-Activity Relationship; Tetrodotoxin; Transfection; Xenopus laevis	2001
Lidocaine partially depolarizes the S4 segment in domain IV of the sodium channel. Pflugers Archiv : European journal of physiology, 2011, Volume: 461, Issue:1 Topics: Anesthetics, Local; Arrhythmias, Cardiac; Humans; Ion Channel Gating; Lidocaine; Membrane Potentials; Mesylates; Protein Structure, Tertiary; Sodium Channels	2011

Article

Year

Structural and gating changes of the sodium channel induced by mutation of a residue in the upper third of IVS6, creating an external access path for local anesthetics.

Molecular pharmacology, 2001, Volume: 59, Issue:4

Topics: Amino Acid Substitution; Anesthetics, Local; Animals; Calcium Channel Blockers; Cells, Cultured; Conotoxins; Ethyl Methanesulfonate; Ion Channel Gating; Lidocaine; Mesylates; Mutagenesis, Site-Directed; Oocytes; Patch-Clamp Techniques; Protein Isoforms; Rats; Saxitoxin; Sodium Channel Blockers; Sodium Channels; Structure-Activity Relationship; Tetrodotoxin; Transfection; Xenopus laevis

2001

Lidocaine partially depolarizes the S4 segment in domain IV of the sodium channel.

Pflugers Archiv : European journal of physiology, 2011, Volume: 461, Issue:1

Topics: Anesthetics, Local; Arrhythmias, Cardiac; Humans; Ion Channel Gating; Lidocaine; Membrane Potentials; Mesylates; Protein Structure, Tertiary; Sodium Channels

2011