Compounds > (11S-14S)-Cyclo-(L-Trp-L-Phe)

(11S-14S)-Cyclo-(L-Trp-L-Phe) and phevalin

(11S-14S)-Cyclo-(L-Trp-L-Phe) has been researched along with phevalin* in 1 studies

Other Studies

1 other study(ies) available for (11S-14S)-Cyclo-(L-Trp-L-Phe) and phevalin

Article	Year
Synthesis of a small library of diketopiperazines as potential inhibitors of calpain. Bioorganic & medicinal chemistry letters, 2005, Jun-15, Volume: 15, Issue:12 A small library of 2,5-diketopiperazines based on previously reported calpain inhibitors was synthesized. In addition, a concise total synthesis of the structurally related natural product phevalin (2) was accomplished. Despite literature reports that some of the compounds prepared were calpain inhibitors, none of the library members were found to have significant activity against recombinant human calpain I. Topics: Calpain; Combinatorial Chemistry Techniques; Cysteine Proteinase Inhibitors; Diketopiperazines; Humans; Molecular Structure; Peptide Library; Piperazines; Pyrazines; Recombinant Proteins; Structure-Activity Relationship	2005

Article

Year

Synthesis of a small library of diketopiperazines as potential inhibitors of calpain.

Bioorganic & medicinal chemistry letters, 2005, Jun-15, Volume: 15, Issue:12

A small library of 2,5-diketopiperazines based on previously reported calpain inhibitors was synthesized. In addition, a concise total synthesis of the structurally related natural product phevalin (2) was accomplished. Despite literature reports that some of the compounds prepared were calpain inhibitors, none of the library members were found to have significant activity against recombinant human calpain I.

Topics: Calpain; Combinatorial Chemistry Techniques; Cysteine Proteinase Inhibitors; Diketopiperazines; Humans; Molecular Structure; Peptide Library; Piperazines; Pyrazines; Recombinant Proteins; Structure-Activity Relationship

2005