Page last updated: 2024-09-05

(-)-gallocatechin gallate and epigallocatechin gallate

(-)-gallocatechin gallate has been researched along with epigallocatechin gallate in 15 studies

Compound Research Comparison

Studies
((-)-gallocatechin gallate)
Trials
((-)-gallocatechin gallate)
Recent Studies (post-2010)
((-)-gallocatechin gallate)
Studies
(epigallocatechin gallate)
Trials
(epigallocatechin gallate)
Recent Studies (post-2010) (epigallocatechin gallate)
190105,4561733,403

Protein Interaction Comparison

ProteinTaxonomy(-)-gallocatechin gallate (IC50)epigallocatechin gallate (IC50)
Chain A, POLYMERASE PAInfluenza A virus1.9
Chain A, Polymerase PaInfluenza A virus (A/California/04/2009(H1N1))1.9
Chain A, Polymerase PaInfluenza A virus (A/California/04/2009(H1N1))1.9
Chain A, Polymerase PaInfluenza A virus (A/California/04/2009(H1N1))1.9
Chain A, Polymerase PaInfluenza A virus (A/California/04/2009(H1N1))1.9
Prostaglandin E synthaseHomo sapiens (human)1.8
Telomerase reverse transcriptaseHomo sapiens (human)1.0867
NAD kinaseHomo sapiens (human)0.96
Urokinase-type plasminogen activatorHomo sapiens (human)0.091
Tissue-type plasminogen activatorHomo sapiens (human)0.091
Polymerase acidic proteinInfluenza A virus (A/Puerto Rico/8/1934(H1N1))5.86
Amyloid-beta precursor proteinHomo sapiens (human)2.7
Plasminogen activator inhibitor 1Homo sapiens (human)0.091
Urokinase-type plasminogen activatorMus musculus (house mouse)0.091
ATP-dependent translocase ABCB1Homo sapiens (human)0.1233
72 kDa type IV collagenaseHomo sapiens (human)4.3833
Hepatocyte growth factor receptorHomo sapiens (human)10
MatrilysinHomo sapiens (human)3.34
Enoyl-[acyl-carrier-protein] reductase [NADH] FabIEscherichia coli K-125
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 21.15
Apoptosis regulator Bcl-2Homo sapiens (human)0.45
Microtubule-associated protein tauHomo sapiens (human)1.8
60 kDa heat shock protein, mitochondrialHomo sapiens (human)2.3
Glucose-6-phosphate 1-dehydrogenaseSaccharomyces cerevisiae S288C0.25
Lethal factorBacillus anthracis0.097
Phosphoglycerate mutase 1Homo sapiens (human)0.49
DNA (cytosine-5)-methyltransferase 1Homo sapiens (human)0.5
Proteasome subunit beta type-5Homo sapiens (human)0.543
DNA repair protein RAD52 homologHomo sapiens (human)2.5108
Matrix metalloproteinase-14Homo sapiens (human)6.8
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6Homo sapiens (human)3.34
Squalene monooxygenase Rattus norvegicus (Norway rat)0.69
6-phosphogluconate dehydrogenase, decarboxylatingHomo sapiens (human)0.72
BH3-interacting domain death agonistHomo sapiens (human)1.0733
Beta-secretase 1Homo sapiens (human)1.1785
10 kDa heat shock protein, mitochondrialHomo sapiens (human)2.3
Bcl-2-like protein 1Homo sapiens (human)0.59
Induced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)0.92
Alpha-(1,3)-fucosyltransferase 7Homo sapiens (human)3.34
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1Homo sapiens (human)3.34
Dual specificity tyrosine-phosphorylation-regulated kinase 1AHomo sapiens (human)0.3055
Mitogen-activated protein kinase 14Homo sapiens (human)2.21
Bcl-2-related protein A1Homo sapiens (human)1.79
Thiosulfate sulfurtransferaseHomo sapiens (human)7.3
60 kDa chaperonin Escherichia coli0.47
Sigma non-opioid intracellular receptor 1Cavia porcellus (domestic guinea pig)10
Dual specificity tyrosine-phosphorylation-regulated kinase 1ARattus norvegicus (Norway rat)0.33
Reverse transcriptase/RNaseH Human immunodeficiency virus 10.73
10 kDa chaperonin Escherichia coli0.47
3-oxoacyl-[acyl-carrier-protein] reductase Plasmodium falciparum 3D70.32
MAP kinase-activated protein kinase 5Homo sapiens (human)1
Bcl-2-like protein 2Homo sapiens (human)2.33
Enoyl-acyl-carrier protein reductase Plasmodium falciparum (malaria parasite P. falciparum)0.225
3-oxoacyl-acyl-carrier protein reductase Plasmodium falciparum (malaria parasite P. falciparum)0.3
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)Plasmodium falciparum (malaria parasite P. falciparum)0.215
Bcl-2-like protein 10Homo sapiens (human)0.36

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (6.67)18.2507
2000's6 (40.00)29.6817
2010's4 (26.67)24.3611
2020's4 (26.67)2.80

Authors

AuthorsStudies
Hong, CY; Huang, SS; Yeh, SF1
Backleh-Sohrt, M; Ekici, P; Leupold, G; Parlar, H1
Brun, R; Lack, G; Perozzo, R; Rüedi, P; Scapozza, L; Tasdemir, D1
Cai, L; Gochin, M1
Corbo, C; Di Maggio, V; Hillier, S; Isaacs, CE; Jenkins, EC; Jia, JH; Rohan, L; Wen, GY; Xu, W1
Cho, D; Cho, SY; Ham, M; Kim, JB; Lee, TR; Park, J; Shin, DW; Shin, ES; Shin, JM1
Bisson, WH; Dashwood, RH; Larsen, CA1
Fujiwara, K; Murakami, N; Tamura, S; Yoshihira, K1
Adam, AT; Bhat, R; Gasiewicz, TA; Henry, EC; Lee, JJ; Rotella, DP1
Adam, AT; Bhat, R; Deloison, G; Lee, JJ; Rotella, DP; Rouillé, Y; Séron, K1
Golonko, A; Lazny, R; Lewandowski, W; Pienkowski, T; Roszko, M; Swislocka, R1
Bernatchez, JA; Li, J; Li, R; Luan, Y; Siqueira-Neto, JL; Tran, LT1
Cao, W; Jian, Y; Ju, X; Li, H; Liang, C; Liu, H; Liu, Y; Ren, X; Tian, L; Wang, Y; Xie, X; Xin, L; Zhang, D; Zhao, Q1
Chen, J; Chen, W; Choudhry, N; Xu, D; Yang, Z; Zanin, M; Zhao, X1
Araldi, GL; Hwang, YW1

Reviews

4 review(s) available for (-)-gallocatechin gallate and epigallocatechin gallate

ArticleYear
Another look at phenolic compounds in cancer therapy the effect of polyphenols on ubiquitin-proteasome system.
    European journal of medicinal chemistry, 2019, Apr-01, Volume: 167

    Topics: Animals; Diet; Humans; Neoplasms; Phenols; Polyphenols; Proteasome Endopeptidase Complex; Ubiquitin

2019
Drugs for the Treatment of Zika Virus Infection.
    Journal of medicinal chemistry, 2020, 01-23, Volume: 63, Issue:2

    Topics: Animals; Antiviral Agents; Drug Development; Drug Discovery; Humans; Viral Vaccines; Zika Virus; Zika Virus Infection

2020
The development of Coronavirus 3C-Like protease (3CL
    European journal of medicinal chemistry, 2020, Nov-15, Volume: 206

    Topics: Antiviral Agents; Coronavirus 3C Proteases; Cysteine Endopeptidases; Humans; Peptidomimetics; Protease Inhibitors; Viral Nonstructural Proteins

2020
Chinese Therapeutic Strategy for Fighting COVID-19 and Potential Small-Molecule Inhibitors against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).
    Journal of medicinal chemistry, 2020, 11-25, Volume: 63, Issue:22

    Topics: Antiviral Agents; China; Coronavirus Protease Inhibitors; COVID-19; COVID-19 Drug Treatment; Drugs, Chinese Herbal; Humans; Medicine, Chinese Traditional; SARS-CoV-2; Small Molecule Libraries

2020

Other Studies

11 other study(ies) available for (-)-gallocatechin gallate and epigallocatechin gallate

ArticleYear
Effect of anthraquinone derivatives on lipid peroxidation in rat heart mitochondria: structure-activity relationship.
    Journal of natural products, 1995, Volume: 58, Issue:9

    Topics: Animals; Anthraquinones; Antioxidants; Free Radical Scavengers; In Vitro Techniques; Lipid Peroxidation; Male; Mitochondria, Heart; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship

1995
Efficiency of foam fractionation for the enrichment of nonpolar compounds from aqueous extracts of plant materials.
    Journal of natural products, 2005, Volume: 68, Issue:9

    Topics: Carotenoids; Chemical Fractionation; Chromatography, High Pressure Liquid; Citrus; Curcuma; Curcumin; Cyclohexenes; Daucus carota; Flavanones; Hesperidin; Molecular Structure; Plant Extracts; Tea; Terpenes; Water

2005
Inhibition of Plasmodium falciparum fatty acid biosynthesis: evaluation of FabG, FabZ, and FabI as drug targets for flavonoids.
    Journal of medicinal chemistry, 2006, Jun-01, Volume: 49, Issue:11

    Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Reductase; Alcohol Oxidoreductases; Animals; Antimalarials; Catechin; Cells, Cultured; Chloroquine; Drug Resistance; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Fatty Acids; Flavones; Flavonoids; Humans; Hydro-Lyases; Kinetics; Luteolin; Phenols; Plasmodium falciparum; Polyphenols; Structure-Activity Relationship

2006
A novel fluorescence intensity screening assay identifies new low-molecular-weight inhibitors of the gp41 coiled-coil domain of human immunodeficiency virus type 1.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:7

    Topics: Anti-HIV Agents; Biological Assay; Dose-Response Relationship, Drug; Fluorescence; HIV Envelope Protein gp41; HIV Fusion Inhibitors; HIV-1; Humans; Hydrophobic and Hydrophilic Interactions; Inhibitory Concentration 50; Membrane Fusion; Molecular Weight; Peptides; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Reproducibility of Results; Thermodynamics

2007
Epigallocatechin gallate inactivates clinical isolates of herpes simplex virus.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:3

    Topics: Animals; Catechin; Cell Line; Chlorocebus aethiops; Dose-Response Relationship, Drug; Female; Herpes Simplex; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Microscopy, Electron; Vero Cells; Virion; Virus Inactivation

2008
Catechin gallates are NADP+-competitive inhibitors of glucose-6-phosphate dehydrogenase and other enzymes that employ NADP+ as a coenzyme.
    Bioorganic & medicinal chemistry, 2008, Apr-01, Volume: 16, Issue:7

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Catechin; Coenzymes; Glucosephosphate Dehydrogenase; Humans; Kinetics; Mice; Molecular Structure; NADP; Structure-Activity Relationship

2008
Tea catechins inhibit hepatocyte growth factor receptor (MET kinase) activity in human colon cancer cells: kinetic and molecular docking studies.
    Journal of medicinal chemistry, 2009, Nov-12, Volume: 52, Issue:21

    Topics: Antineoplastic Agents; Camellia sinensis; Catechin; Cell Line, Tumor; Colonic Neoplasms; Drug Screening Assays, Antitumor; Flavonoids; Gallic Acid; Humans; Kinetics; Models, Molecular; Phenols; Polyphenols; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-met; Receptors, Growth Factor; Structure-Activity Relationship

2009
New inhibitors for expression of IgE receptor on human mast cell.
    Bioorganic & medicinal chemistry letters, 2010, Apr-01, Volume: 20, Issue:7

    Topics: Anthocyanins; Anti-Allergic Agents; Catechin; Cell Line; Flavones; Flavonoids; Gene Expression; Humans; Hypersensitivity; Mast Cells; Receptors, IgE

2010
Towards the discovery of drug-like epigallocatechin gallate analogs as Hsp90 inhibitors.
    Bioorganic & medicinal chemistry letters, 2014, May-15, Volume: 24, Issue:10

    Topics: Biological Products; Catechin; Drug Discovery; HSP90 Heat-Shock Proteins; Structure-Activity Relationship

2014
Structure-activity studies of (-)-epigallocatechin gallate derivatives as HCV entry inhibitors.
    Bioorganic & medicinal chemistry letters, 2014, Sep-01, Volume: 24, Issue:17

    Topics: Antiviral Agents; Catechin; Cell Survival; Dose-Response Relationship, Drug; Hepacivirus; Humans; Microbial Sensitivity Tests; Molecular Structure; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured; Virus Internalization

2014
Design, synthesis, and biological evaluation of polyphenol derivatives as DYRK1A inhibitors. The discovery of a potentially promising treatment for Multiple Sclerosis.
    Bioorganic & medicinal chemistry letters, 2022, 05-15, Volume: 64

    Topics: Catechin; Humans; Multiple Sclerosis; Phosphorylation; Polyphenols; Structure-Activity Relationship; Tea

2022