Page last updated: 2024-09-05

(-)-gallocatechin gallate and epicatechin gallate

(-)-gallocatechin gallate has been researched along with epicatechin gallate in 12 studies

Compound Research Comparison

Studies
((-)-gallocatechin gallate)
Trials
((-)-gallocatechin gallate)
Recent Studies (post-2010)
((-)-gallocatechin gallate)
Studies
(epicatechin gallate)
Trials
(epicatechin gallate)
Recent Studies (post-2010) (epicatechin gallate)
190104874225

Protein Interaction Comparison

ProteinTaxonomy(-)-gallocatechin gallate (IC50)epicatechin gallate (IC50)
Synaptojanin-2Homo sapiens (human)2.88
Hepatocyte growth factor receptorHomo sapiens (human)10
Enoyl-[acyl-carrier-protein] reductase [NADH] FabIEscherichia coli K-1210
Glucose-6-phosphate 1-dehydrogenaseSaccharomyces cerevisiae S288C0.18
Proteasome subunit beta type-5Homo sapiens (human)0.194
Alpha-synucleinHomo sapiens (human)9.8
DNA repair protein RAD52 homologHomo sapiens (human)0.255
6-phosphogluconate dehydrogenase, decarboxylatingHomo sapiens (human)0.21
Dual specificity tyrosine-phosphorylation-regulated kinase 1AHomo sapiens (human)0.523
ELAV-like protein 3Homo sapiens (human)0.2
Mitogen-activated protein kinase 14Homo sapiens (human)1.47
Sigma non-opioid intracellular receptor 1Cavia porcellus (domestic guinea pig)10
Reverse transcriptase/RNaseH Human immunodeficiency virus 10.76
Enoyl-acyl-carrier protein reductase Plasmodium falciparum (malaria parasite P. falciparum)0.35
3-oxoacyl-acyl-carrier protein reductase Plasmodium falciparum (malaria parasite P. falciparum)1
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)Plasmodium falciparum (malaria parasite P. falciparum)0.4
Solute carrier organic anion transporter family member 1B3Homo sapiens (human)4.4668
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)3.8019

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (8.33)18.2507
2000's5 (41.67)29.6817
2010's4 (33.33)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Hong, CY; Huang, SS; Yeh, SF1
Backleh-Sohrt, M; Ekici, P; Leupold, G; Parlar, H1
Brun, R; Lack, G; Perozzo, R; Rüedi, P; Scapozza, L; Tasdemir, D1
Corbo, C; Di Maggio, V; Hillier, S; Isaacs, CE; Jenkins, EC; Jia, JH; Rohan, L; Wen, GY; Xu, W1
Cho, D; Cho, SY; Ham, M; Kim, JB; Lee, TR; Park, J; Shin, DW; Shin, ES; Shin, JM1
Bisson, WH; Dashwood, RH; Larsen, CA1
Fujiwara, K; Murakami, N; Tamura, S; Yoshihira, K1
Liu, Y; Nair, MG1
Oliveri, V1
Golonko, A; Lazny, R; Lewandowski, W; Pienkowski, T; Roszko, M; Swislocka, R1
Bernatchez, JA; Li, J; Li, R; Luan, Y; Siqueira-Neto, JL; Tran, LT1
Araldi, GL; Hwang, YW1

Reviews

3 review(s) available for (-)-gallocatechin gallate and epicatechin gallate

ArticleYear
Toward the discovery and development of effective modulators of α-synuclein amyloid aggregation.
    European journal of medicinal chemistry, 2019, Apr-01, Volume: 167

    Topics: alpha-Synuclein; Amyloidogenic Proteins; Drug Discovery; Humans; Protein Aggregation, Pathological; Structure-Activity Relationship

2019
Another look at phenolic compounds in cancer therapy the effect of polyphenols on ubiquitin-proteasome system.
    European journal of medicinal chemistry, 2019, Apr-01, Volume: 167

    Topics: Animals; Diet; Humans; Neoplasms; Phenols; Polyphenols; Proteasome Endopeptidase Complex; Ubiquitin

2019
Drugs for the Treatment of Zika Virus Infection.
    Journal of medicinal chemistry, 2020, 01-23, Volume: 63, Issue:2

    Topics: Animals; Antiviral Agents; Drug Development; Drug Discovery; Humans; Viral Vaccines; Zika Virus; Zika Virus Infection

2020

Other Studies

9 other study(ies) available for (-)-gallocatechin gallate and epicatechin gallate

ArticleYear
Effect of anthraquinone derivatives on lipid peroxidation in rat heart mitochondria: structure-activity relationship.
    Journal of natural products, 1995, Volume: 58, Issue:9

    Topics: Animals; Anthraquinones; Antioxidants; Free Radical Scavengers; In Vitro Techniques; Lipid Peroxidation; Male; Mitochondria, Heart; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship

1995
Efficiency of foam fractionation for the enrichment of nonpolar compounds from aqueous extracts of plant materials.
    Journal of natural products, 2005, Volume: 68, Issue:9

    Topics: Carotenoids; Chemical Fractionation; Chromatography, High Pressure Liquid; Citrus; Curcuma; Curcumin; Cyclohexenes; Daucus carota; Flavanones; Hesperidin; Molecular Structure; Plant Extracts; Tea; Terpenes; Water

2005
Inhibition of Plasmodium falciparum fatty acid biosynthesis: evaluation of FabG, FabZ, and FabI as drug targets for flavonoids.
    Journal of medicinal chemistry, 2006, Jun-01, Volume: 49, Issue:11

    Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Reductase; Alcohol Oxidoreductases; Animals; Antimalarials; Catechin; Cells, Cultured; Chloroquine; Drug Resistance; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Fatty Acids; Flavones; Flavonoids; Humans; Hydro-Lyases; Kinetics; Luteolin; Phenols; Plasmodium falciparum; Polyphenols; Structure-Activity Relationship

2006
Epigallocatechin gallate inactivates clinical isolates of herpes simplex virus.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:3

    Topics: Animals; Catechin; Cell Line; Chlorocebus aethiops; Dose-Response Relationship, Drug; Female; Herpes Simplex; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Microscopy, Electron; Vero Cells; Virion; Virus Inactivation

2008
Catechin gallates are NADP+-competitive inhibitors of glucose-6-phosphate dehydrogenase and other enzymes that employ NADP+ as a coenzyme.
    Bioorganic & medicinal chemistry, 2008, Apr-01, Volume: 16, Issue:7

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Catechin; Coenzymes; Glucosephosphate Dehydrogenase; Humans; Kinetics; Mice; Molecular Structure; NADP; Structure-Activity Relationship

2008
Tea catechins inhibit hepatocyte growth factor receptor (MET kinase) activity in human colon cancer cells: kinetic and molecular docking studies.
    Journal of medicinal chemistry, 2009, Nov-12, Volume: 52, Issue:21

    Topics: Antineoplastic Agents; Camellia sinensis; Catechin; Cell Line, Tumor; Colonic Neoplasms; Drug Screening Assays, Antitumor; Flavonoids; Gallic Acid; Humans; Kinetics; Models, Molecular; Phenols; Polyphenols; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-met; Receptors, Growth Factor; Structure-Activity Relationship

2009
New inhibitors for expression of IgE receptor on human mast cell.
    Bioorganic & medicinal chemistry letters, 2010, Apr-01, Volume: 20, Issue:7

    Topics: Anthocyanins; Anti-Allergic Agents; Catechin; Cell Line; Flavones; Flavonoids; Gene Expression; Humans; Hypersensitivity; Mast Cells; Receptors, IgE

2010
An efficient and economical MTT assay for determining the antioxidant activity of plant natural product extracts and pure compounds.
    Journal of natural products, 2010, Jul-23, Volume: 73, Issue:7

    Topics: Antioxidants; Coloring Agents; Formazans; Free Radical Scavengers; Mitochondria; Molecular Structure; NADP; Oxidation-Reduction; Plant Extracts; Singlet Oxygen; Tetrazolium Salts; Thiazoles

2010
Design, synthesis, and biological evaluation of polyphenol derivatives as DYRK1A inhibitors. The discovery of a potentially promising treatment for Multiple Sclerosis.
    Bioorganic & medicinal chemistry letters, 2022, 05-15, Volume: 64

    Topics: Catechin; Humans; Multiple Sclerosis; Phosphorylation; Polyphenols; Structure-Activity Relationship; Tea

2022