alpha-Dystroglycanopathies

Rare autosomal recessive lissencephaly type 2 associated with congenital MUSCULAR DYSTROPHY and eye anomalies (e.g., RETINAL DETACHMENT; CATARACT; MICROPHTHALMOS). It is often associated with additional brain malformations such as HYDROCEPHALY and cerebellar hypoplasia and is the most severe form of the group of related syndromes (alpha-dystroglycanopathies) with common congenital abnormalities in the brain, eye and muscle development.

Synonym
Fukuyama Syndrome
Fukuyama Type Congenital Muscular Dystrophy
MEB (Muscle-Eye-Brain) Syndrome
Muscular Dystrophy-Dystroglycanopathy (Congenital with Brain and Eye Anomalies), Type A, 1
Muscular Dystrophy, Limb-Girdle, Autosomal Recessive, With Mental Retardation
Hydrocephalus, Agyria, And Retinal Dysplasia
HARD Syndrome
Congenital Muscular Dystrophy-Dystroglycanopathy with Brain and Eye Anomalies, Type A1
Warburg Syndrome
Cerebroocular Dysplasia-Muscular Dystrophy Syndrome
Muscular Dystrophy, Limb-Girdle, Type 2K
Muscular Dystrophy, Congenital, Fukuyama Type
COD-MD Syndrome
Pagon Syndrome
Muscle-Eye-Brain Disease
Chemke Syndrome
alpha-Dystroglycanopathies
Muscle-Eye-Brain Disease, POMT1-Related
LGMD2K
Muscular Dystrophy-Dystroglycanopathy (Limb-Girdle), Type C, 1
Cerebromuscular Dystrophy, Fukuyama Type
Walker-Warburg Syndrome
Muscle Eye Brain Disease
Fukuyama CMD
Fukuyama Congenital Muscular Dystrophy
MDDGA1
Fukuyama Muscular Dystrophy

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	0 (0.00)	23.3326
1990's	0 (0.00)	12.5806
2000's	0 (0.00)	18.1394
2010's	17 (80.95)	28.8240
2020's	4 (19.05)	9.53

Drug	Relationship Strength	Studies
carnitine	low	1
choline	low	1
creatine	low	1
lactic acid	low	2
nocodazole	low	1
propofol	low	1
succinylcholine	low	1
prednisolone	low	1
cytidine monophosphate	low	1
xylitol	low	1
mannose	low	5
acetylglucosamine	low	1
remifentanil	low	1
cephalosporin c	low	1
ribitol-5-phosphate	low	1
n-acetylneuraminic acid	low	1
n-acetyllactosamine	low	1
curcumin	low	1
myelin basic protein	low	1
brefeldin a	low	1
piperidines	low	1
nephrin	low	1
eye	low	4

Protein Targets (413)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
hypoxia-inducible factor 1 alpha subunit	3	0	0	3
RAR-related orphan receptor gamma	5	0	0	5
GLI family zinc finger 3	6	0	0	6
AR protein	5	0	0	5
aldehyde dehydrogenase 1 family, member A1	3	0	0	3
retinoic acid nuclear receptor alpha variant 1	7	0	0	7
retinoid X nuclear receptor alpha	4	0	0	4
estrogen nuclear receptor alpha	7	0	0	7
peroxisome proliferator-activated receptor delta	3	0	0	3
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	5	0	0	5
activating transcription factor 6	3	0	0	3
v-jun sarcoma virus 17 oncogene homolog (avian)	6	0	0	6
Histone H2A.x	4	0	0	4
thyroid hormone receptor beta isoform a	3	0	0	3
heat shock protein beta-1	3	0	0	3
nuclear factor erythroid 2-related factor 2 isoform 1	4	0	0	4
lamin isoform A-delta10	4	0	0	4
Voltage-dependent calcium channel gamma-2 subunit	4	0	0	4
Glutamate receptor 2	4	0	0	4
Putative glycosyltransferase WbgO	0	0	0	1
Cytochrome P450 3A4	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
Killer cell lectin-like receptor subfamily B member 1A	0	1	0	1
Early activation antigen CD69	0	1	0	1
PAX8	0	0	0	1
thioredoxin reductase	3	0	0	3
ATAD5 protein, partial	3	0	0	3
USP1 protein, partial	4	0	0	4
TDP1 protein	4	0	0	4
thioredoxin glutathione reductase	2	0	0	2
Smad3	3	0	0	3
67.9K protein	2	0	0	2
IDH1	3	0	0	3
euchromatic histone-lysine N-methyltransferase 2	6	0	0	6
NPC intracellular cholesterol transporter 1 precursor	2	0	0	2
major prion protein preproprotein Prp precursor	0	1	0	1
nuclear receptor subfamily 0 group B member 1	0	2	0	2
chromobox protein homolog 1	3	0	0	3
nuclear factor erythroid 2-related factor 2 isoform 2	3	0	0	3
ras-related protein Rab-9A	1	0	0	1
steroidogenic factor 1	0	2	0	2
urokinase-type plasminogen activator precursor	2	0	0	2
plasminogen precursor	2	0	0	2
urokinase plasminogen activator surface receptor precursor	2	0	0	2
geminin	3	0	0	3
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 5	0	0	0	1
Bile salt export pump	0	2	0	2
Solute carrier family 22 member 16	0	0	0	1
Solute carrier family 22 member 21	0	0	0	1
Solute carrier family 22 member 5	0	0	0	1
Chain A, Acetylcholinesterase	0	0	2	2
Chain A, Acetylcholinesterase	0	0	2	2
Chain A, Acetylcholinesterase	0	0	2	2
Chain A, Acetylcholinesterase	0	0	2	2
Chain A, Acetylcholinesterase	0	0	2	2
Chain A, Acetylcholinesterase	0	0	2	2
Chain A, Acetylcholinesterase	0	0	2	2
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein	0	0	1	1
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Choline-binding protein	0	0	1	1
muscarinic acetylcholine receptor M1	2	0	0	2
Solute carrier family 22 member 1	0	1	0	2
Solute carrier family 22 member 2	0	0	0	1
Solute carrier family 22 member 1	0	0	0	1
Solute carrier family 22 member 2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-3	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	0	1	0	1
Neuronal acetylcholine receptor subunit beta-3	0	1	0	1
Neuronal acetylcholine receptor subunit beta-4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-5	0	1	0	1
Acetylcholinesterase	0	2	0	2
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Choline O-acetyltransferase	0	0	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-9	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Solute carrier family 22 member 1	0	1	0	2
High affinity choline transporter 1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-10	0	1	0	1
Solute carrier family 22 member 2	0	1	0	2
ATP-dependent phosphofructokinase	2	0	0	2
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Proton-coupled amino acid transporter 1	0	1	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	1	0	0	1
Chain A, Breast cancer type 1 susceptibility protein	1	0	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	1	0	0	1
Chain A, HADH2 protein	1	0	0	1
Chain B, HADH2 protein	1	0	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	1	0	0	1
Chain A, 2-oxoglutarate Oxygenase	1	0	0	1
Chain A, Ferritin light chain	2	0	0	2
Chain A, Cruzipain	1	0	0	1
Luciferase	2	0	0	2
interleukin 8	1	0	0	1
acetylcholinesterase	2	0	0	2
Nrf2	1	0	0	1
15-lipoxygenase, partial	1	0	0	1
pregnane X receptor	1	0	0	1
phosphopantetheinyl transferase	2	0	0	2
SMAD family member 2	1	0	0	1
GLS protein	2	0	0	2
SMAD family member 3	1	0	0	1
Microtubule-associated protein tau	2	0	0	2
alkaline phosphatase, intestinal	0	1	0	1
apical membrane antigen 1, AMA1	1	0	0	1
caspase 7, apoptosis-related cysteine protease	3	0	0	3
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	3	0	0	3
PINK1	1	0	0	1
thyroid stimulating hormone receptor	3	0	0	3
estrogen receptor 2 (ER beta)	2	0	0	2
nuclear receptor subfamily 1, group I, member 3	2	0	0	2
progesterone receptor	4	0	0	4
EWS/FLI fusion protein	1	0	0	2
glucocorticoid receptor [Homo sapiens]	3	0	0	3
estrogen-related nuclear receptor alpha	6	0	0	6
farnesoid X nuclear receptor	3	0	0	3
pregnane X nuclear receptor	4	0	0	4
glucocerebrosidase	1	0	0	1
Parkin	1	0	0	1
bromodomain adjacent to zinc finger domain 2B	1	0	0	1
toll-like receptor 9	0	1	0	1
peroxisome proliferator activated receptor gamma	1	0	0	1
vitamin D (1,25- dihydroxyvitamin D3) receptor	2	0	0	2
caspase-3	3	0	0	3
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	1	0	0	1
TPA: protein transporter TIM10	0	1	0	1
aryl hydrocarbon receptor	3	0	0	3
thyroid stimulating hormone receptor	2	0	0	2
thyrotropin-releasing hormone receptor	1	0	0	1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	2	0	0	2
lysosomal alpha-glucosidase preproprotein	1	0	0	1
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein	0	1	0	1
hemoglobin subunit beta	1	0	0	1
cellular tumor antigen p53 isoform a	3	0	0	3
polyunsaturated fatty acid lipoxygenase ALOX12	1	0	0	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	2	0	0	2
perilipin-5	0	1	0	1
vitamin D3 receptor isoform VDRA	1	0	0	1
intestinal alkaline phosphatase precursor	0	1	0	1
perilipin-1	0	1	0	1
potassium voltage-gated channel subfamily H member 2 isoform d	1	0	0	1
transcriptional regulator ERG isoform 3	2	0	0	2
thyroid hormone receptor beta isoform 2	3	0	0	3
huntingtin isoform 2	2	0	0	2
importin subunit beta-1 isoform 1	1	0	0	1
pyruvate kinase PKM isoform a	1	0	0	1
DNA polymerase beta	1	0	0	1
mitogen-activated protein kinase 1	2	0	0	2
nuclear factor NF-kappa-B p105 subunit isoform 1	1	0	0	1
flap endonuclease 1	1	0	0	1
snurportin-1	1	0	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	1	0	0	1
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	1	0	0	1
tumor susceptibility gene 101 protein	1	0	0	1
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
DNA polymerase iota isoform a (long)	2	0	0	2
nuclear receptor ROR-gamma isoform 1	2	0	0	2
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	1	0	1
DNA polymerase kappa isoform 1	3	0	0	3
peripheral myelin protein 22	2	0	0	2
cytochrome P450 3A4 isoform 1	2	0	0	2
muscleblind-like protein 1 isoform 1	1	0	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	0	0	1
alkaline phosphatase, germ cell type preproprotein	0	1	0	1
caspase-1 isoform alpha precursor	1	0	0	1
hypothetical protein SA1422	0	1	0	1
lethal factor (plasmid)	2	0	0	2
DNA dC->dU-editing enzyme APOBEC-3F isoform a	1	0	0	1
neuropeptide S receptor isoform A	2	0	0	2
Gamma-aminobutyric acid receptor subunit pi	2	1	1	4
Prostaglandin E synthase	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	1	0	0	1
Histone deacetylase 3	0	1	0	1
Acetylcholinesterase	0	1	0	1
Lysine-specific histone demethylase 1A	0	1	0	1
D-amino-acid oxidase	0	1	0	1
Phospholipase A2	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	2	0	2
Cellular tumor antigen p53	4	0	0	4
Amyloid-beta precursor protein	0	1	0	2
Integrin beta-3	2	0	0	2
Neuronal proto-oncogene tyrosine-protein kinase Src	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Cholinesterase	0	1	0	1
Heme oxygenase 1	0	1	0	1
Integrin alpha-IIb	2	0	0	2
Glutathione S-transferase P	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
60 kDa chaperonin	0	1	0	1
Replicase polyprotein 1ab	0	1	1	2
Replicase polyprotein 1ab	0	1	1	2
Microtubule-associated protein tau	0	1	0	2
60 kDa heat shock protein, mitochondrial	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	0	1	0	1
Tissue factor	0	1	0	1
Tyrosinase	0	1	0	1
Aminopeptidase N	0	1	0	1
Aminopeptidase N	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	2	1	1	4
Alpha-1B adrenergic receptor	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	0	2	0	2
Glycogen synthase kinase-3 beta	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	2	1	1	4
Gamma-aminobutyric acid receptor subunit gamma-2	2	1	1	4
Gamma-aminobutyric acid receptor subunit alpha-5	2	1	1	4
Gamma-aminobutyric acid receptor subunit alpha-3	2	1	1	4
Amine oxidase [flavin-containing] A	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	2	1	1	4
Gamma-aminobutyric acid receptor subunit alpha-2	2	1	1	4
Heme oxygenase 2	0	1	0	1
Alpha-1D adrenergic receptor	0	1	0	1
Amine oxidase [flavin-containing] B	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Proteasome subunit beta type-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	2	1	1	4
Gamma-aminobutyric acid receptor subunit gamma-3	2	1	1	4
Gamma-aminobutyric acid receptor subunit alpha-6	2	1	1	4
Prostaglandin G/H synthase 2	0	2	0	2
17-beta-hydroxysteroid dehydrogenase type 2	0	1	0	1
Alpha-synuclein	1	1	1	3
Alpha-1A adrenergic receptor	0	1	0	1
Histamine H2 receptor	2	0	0	2
Glycogen synthase kinase-3 beta	0	1	0	1
Nuclear receptor ROR-gamma	1	0	0	1
Caspase-7	1	0	0	1
Histone deacetylase 4	0	1	0	1
Beta-secretase 1	0	1	0	1
10 kDa heat shock protein, mitochondrial	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	2	1	1	4
Gamma-aminobutyric acid receptor subunit beta-3	2	1	1	4
Guanine nucleotide-binding protein G	1	0	0	1
Gamma-aminobutyric acid receptor subunit beta-2	2	1	1	4
Cholinesterase	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Lactoylglutathione lyase	0	1	0	1
Histone acetyltransferase p300	0	1	0	1
TAR DNA-binding protein 43	1	0	0	1
Serine/threonine-protein kinase PAK 1	0	1	0	1
Histone deacetylase 1	0	2	0	2
5-hydroxytryptamine receptor 4	0	0	1	1
Sodium/bile acid cotransporter	0	0	1	1
Nuclear factor erythroid 2-related factor 2	0	0	1	1
Thiosulfate sulfurtransferase	0	1	0	1
Thioredoxin reductase 1, cytoplasmic	0	1	0	1
60 kDa chaperonin	0	1	0	1
10 kDa chaperonin	0	1	0	1
Thioredoxin reductase 3	0	1	0	1
Sortase A	0	1	0	1
Histone deacetylase 7	0	1	0	1
GABA theta subunit	2	1	1	4
Histone deacetylase 2	0	2	0	2
CREB-binding protein	1	1	0	2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3	0	2	0	2
Cysteine protease	0	1	0	1
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 11	0	1	0	1
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
ATPase family AAA domain-containing protein 5	3	0	0	3
Ataxin-2	3	0	0	3
Histone deacetylase 8	0	2	0	2
Gamma-aminobutyric acid receptor subunit epsilon	2	1	1	4
Thioredoxin reductase 2, mitochondrial	0	1	0	1
CDGSH iron-sulfur domain-containing protein 1	0	2	0	2
Histone deacetylase 6	0	1	0	1
Histone deacetylase 9	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	1	0	1
Histone deacetylase 5	0	1	0	1
Lymphocyte antigen 96	0	0	1	1
Beta lactamase (plasmid)	0	1	0	1
Orotidine 5'-phosphate decarboxylase	0	1	0	1
Seminal ribonuclease	0	1	0	1
Uridine 5'-monophosphate synthase	0	1	0	1
Beta-galactoside alpha-2,6-sialyltransferase 1	0	1	0	1
UMP-CMP kinase	0	0	0	1
Ribonuclease pancreatic	0	1	0	1
CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase	0	1	0	1
Orotidine 5'-phosphate decarboxylase	0	1	0	1
cytochrome P450 family 3 subfamily A polypeptide 4	3	0	0	3
cytochrome P450 2D6	1	0	0	1
Alpha-mannosidase 2C1	0	1	0	1
Fucose-binding lectin PA-IIL	0	1	0	1
CD209 antigen	0	1	0	1
Chain A, SusD homolog	0	0	1	1
Galectin-9	0	0	1	1
Galectin-8	0	0	1	1
Galectin-1	0	0	1	1
Galectin-3	0	0	1	1
Galectin-7	0	0	1	1
Sialidase-4	0	1	0	1
Sialidase-1	0	1	0	1
Sialidase-3	0	1	0	1
Sialidase-2	0	1	0	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	1	0	0	1
Chain A, Glutathione-requiring prostaglandin D synthase	0	1	0	1
Fumarate hydratase	1	0	0	1
NFKB1 protein, partial	1	0	0	1
PPM1D protein	1	0	0	1
Thrombopoietin	1	0	0	1
G	2	0	0	2
polyprotein	1	0	0	1
arylsulfatase A	1	0	0	1
Bloom syndrome protein isoform 1	2	0	0	2
peripheral myelin protein 22 isoform 1	1	0	0	1
cytochrome P450 2C9 precursor	1	0	0	1
histone deacetylase 9 isoform 3	1	0	0	1
atrial natriuretic peptide receptor 2 precursor	1	0	0	1
serine/threonine-protein kinase mTOR isoform 1	1	0	0	1
Tyrosine-protein kinase ABL1	0	1	0	1
Interferon beta	3	0	0	3
HLA class I histocompatibility antigen, B alpha chain	2	0	0	2
Tubulin alpha-1A chain	0	1	0	1
Tubulin beta chain	0	1	0	1
Tubulin beta-4A chain	0	1	1	2
Tubulin beta chain	0	1	1	2
Tubulin alpha-3C chain	0	1	1	2
Adenosine receptor A2a	0	2	0	2
Adenosine receptor A1	0	2	0	2
5-hydroxytryptamine receptor 2B	0	4	0	4
Tubulin alpha-1B chain	0	1	1	2
Tubulin alpha-4A chain	0	1	1	2
Tubulin beta-4B chain	0	1	1	2
Inositol monophosphatase 1	1	0	0	1
Sodium-dependent dopamine transporter	0	2	0	2
Tubulin beta-3 chain	0	1	1	2
Tubulin beta-2A chain	0	1	1	2
Tubulin beta-8 chain	0	1	1	2
Tubulin beta-2B chain	0	1	0	2
Tubulin alpha-3E chain	0	1	1	2
Tubulin alpha-1A chain	0	1	1	2
Similar to alpha-tubulin isoform 1	0	1	0	2
Similar to alpha-tubulin isoform 1	0	1	0	2
Inositol hexakisphosphate kinase 1	2	0	0	2
Tubulin alpha-1C chain	0	1	1	2
Tubulin beta-6 chain	0	1	1	2
Tubulin beta-2B chain	0	1	1	2
Tubulin beta-1 chain	0	1	1	2
cytochrome P450 2C9, partial	2	0	0	2
luciferase	0	0	0	1
nuclear receptor subfamily 1, group I, member 2	1	0	0	1
ATP-binding cassette sub-family C member 3	0	1	0	1
Multidrug resistance-associated protein 4	0	1	0	1
Fatty acid-binding protein, liver	0	1	0	1
Estrogen receptor	0	2	0	2
Glucocorticoid receptor	0	2	1	8
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Glycine receptor subunit alpha-1	0	2	0	2
Corticosteroid-binding globulin	0	1	0	1
Mineralocorticoid receptor	0	2	1	3
Androgen receptor	0	2	0	2
Cytochrome P450 2C9	0	1	0	1
Glutamine synthetase	0	0	1	1
Androgen receptor	0	1	0	1
Glycine receptor subunit beta	0	2	0	2
Glycine receptor subunit alpha-2	0	2	0	2
Glycine receptor subunit alpha-3	0	2	0	2
Histamine H1 receptor	0	0	1	1
Nociceptin receptor	0	0	1	1
Cytochrome P450 2J2	0	1	0	1
Estrogen receptor beta	0	2	0	2
Canalicular multispecific organic anion transporter 1	0	1	0	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
D(1A) dopamine receptor	2	0	0	2
Fatty-acid amide hydrolase 1	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	0	0	1
5-hydroxytryptamine receptor 4	0	2	0	2
Carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Aldo-keto reductase family 1 member B1	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	0	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	0	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-1	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	0	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	0	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Sodium-dependent noradrenaline transporter	0	2	0	2
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
5-hydroxytryptamine receptor 2C	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-5	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	0	1	1
Gamma-aminobutyric acid receptor subunit beta-2	0	0	1	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	0	1	1
Fatty-acid amide hydrolase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	0	1	1
UDP-glucuronosyltransferase 1A8	0	0	0	1
Mu-type opioid receptor	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	1	0	1
Acetylcholinesterase	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(27)

Research Excerpts

Research

Studies (21)

Protein Targets (413)

alpha-Dystroglycanopathies

Synonyms(27)

Research Excerpts

Research

Studies (21)

Drugs Studied (24)

Protein Targets (413)