| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | 2 | 0 | 0 | 2 |
| Luciferase | 3 | 0 | 0 | 3 |
| euchromatic histone-lysine N-methyltransferase 2 | 2 | 0 | 0 | 2 |
| lamin isoform A-delta10 | 3 | 0 | 0 | 3 |
| Spike glycoprotein | 1 | 0 | 0 | 1 |
| Chain A, Ferritin light chain | 1 | 0 | 0 | 1 |
| acetylcholinesterase | 1 | 0 | 0 | 1 |
| hypoxia-inducible factor 1 alpha subunit | 1 | 0 | 0 | 1 |
| RAR-related orphan receptor gamma | 2 | 0 | 0 | 2 |
| SMAD family member 2 | 2 | 0 | 0 | 2 |
| USP1 protein, partial | 2 | 0 | 0 | 2 |
| SMAD family member 3 | 2 | 0 | 0 | 2 |
| TDP1 protein | 3 | 0 | 0 | 3 |
| GLI family zinc finger 3 | 1 | 0 | 0 | 1 |
| Microtubule-associated protein tau | 1 | 0 | 0 | 1 |
| AR protein | 4 | 0 | 0 | 4 |
| caspase 7, apoptosis-related cysteine protease | 2 | 0 | 0 | 2 |
| estrogen receptor 2 (ER beta) | 3 | 0 | 0 | 3 |
| nuclear receptor subfamily 1, group I, member 3 | 2 | 0 | 0 | 2 |
| progesterone receptor | 1 | 0 | 0 | 1 |
| glucocorticoid receptor [Homo sapiens] | 2 | 0 | 0 | 2 |
| retinoic acid nuclear receptor alpha variant 1 | 3 | 0 | 0 | 3 |
| retinoid X nuclear receptor alpha | 3 | 0 | 0 | 3 |
| estrogen-related nuclear receptor alpha | 3 | 0 | 0 | 3 |
| farnesoid X nuclear receptor | 1 | 0 | 0 | 1 |
| estrogen nuclear receptor alpha | 4 | 0 | 0 | 4 |
| 67.9K protein | 1 | 0 | 0 | 1 |
| peroxisome proliferator-activated receptor delta | 2 | 0 | 0 | 2 |
| peroxisome proliferator activated receptor gamma | 2 | 0 | 0 | 2 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | 2 | 0 | 0 | 2 |
| caspase-3 | 2 | 0 | 0 | 2 |
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 1 | 0 | 0 | 1 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 2 | 0 | 0 | 2 |
| activating transcription factor 6 | 1 | 0 | 0 | 1 |
| thyrotropin-releasing hormone receptor | 1 | 0 | 0 | 1 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | 1 | 0 | 0 | 1 |
| vitamin D3 receptor isoform VDRA | 2 | 0 | 0 | 2 |
| thyroid hormone receptor beta isoform 2 | 4 | 0 | 0 | 4 |
| heat shock protein beta-1 | 1 | 0 | 0 | 1 |
| mitogen-activated protein kinase 1 | 3 | 0 | 0 | 3 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 2 | 0 | 0 | 2 |
| nuclear receptor ROR-gamma isoform 1 | 1 | 0 | 0 | 1 |
| survival motor neuron protein isoform d | 3 | 0 | 0 | 3 |
| Voltage-dependent calcium channel gamma-2 subunit | 2 | 0 | 0 | 2 |
| Cellular tumor antigen p53 | 1 | 0 | 0 | 1 |
| Glutamate receptor 2 | 2 | 0 | 0 | 2 |
| Caspase-2 | 0 | 0 | 1 | 1 |
| Inositol monophosphatase 1 | 1 | 0 | 0 | 1 |
| ATPase family AAA domain-containing protein 5 | 2 | 0 | 0 | 2 |
| Ataxin-2 | 2 | 0 | 0 | 2 |
| Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION | 0 | 0 | 1 | 1 |
| Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION | 0 | 0 | 1 | 1 |
| Chain H, Fab M82G2, Heavy chain | 0 | 0 | 1 | 1 |
| Chain L, Fab M82G2, Light chain | 0 | 0 | 1 | 1 |
| Chain H, Fab M82g2, Heavy Chain | 0 | 0 | 1 | 1 |
| Chain L, Fab M82g2, Light Chain | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | 0 | 1 | 0 | 1 |
| Amyloid-beta precursor protein | 0 | 1 | 0 | 1 |
| Fatty acid-binding protein, heart | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M2 | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M1 | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 2C | 0 | 2 | 0 | 2 |
| Tryptophan 5-hydroxylase 1 | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 2A | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 0 | 1 | 0 | 1 |
| D | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 1A | 0 | 1 | 0 | 1 |
| Alpha-2B adrenergic receptor | 0 | 1 | 0 | 1 |
| Alpha-2C adrenergic receptor | 0 | 1 | 0 | 1 |
| Alpha-2A adrenergic receptor | 0 | 1 | 0 | 1 |
| Liver carboxylesterase 1 | 0 | 0 | 0 | 1 |
| Sodium-dependent noradrenaline transporter | 0 | 2 | 0 | 2 |
| Sodium-dependent dopamine transporter | 0 | 2 | 0 | 2 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 1B | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 1D | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 1F | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 2B | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 6 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 0 | 1 | 0 | 1 |
| Sodium-dependent serotonin transporter | 0 | 2 | 0 | 2 |
| Sodium-dependent serotonin transporter | 0 | 2 | 0 | 3 |
| 5-hydroxytryptamine receptor 7 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 5A | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 5B | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 3A | 0 | 1 | 0 | 1 |
| Lysosomal Pro-X carboxypeptidase | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 0 | 1 | 0 | 1 |
| D(2) dopamine receptor | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 2A | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 2B | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 2C | 0 | 1 | 0 | 1 |
| Sodium-dependent dopamine transporter | 0 | 2 | 0 | 2 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 0 | 1 | 0 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 0 | 1 | 0 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | 0 | 1 | 0 | 1 |
| Leukotriene B4 receptor 1 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 0 | 1 | 0 | 1 |
| Sodium-dependent dopamine transporter | 0 | 2 | 0 | 2 |
| Glutamate receptor ionotropic, NMDA 2D | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 4 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 3B | 0 | 1 | 0 | 1 |
| Sigma non-opioid intracellular receptor 1 | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 3B | 0 | 1 | 0 | 1 |
| Leukotriene B4 receptor 2 | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 3A | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit theta | 0 | 1 | 0 | 1 |
| Transporter | 0 | 2 | 0 | 2 |
| phosphopantetheinyl transferase | 1 | 0 | 0 | 1 |
| potassium voltage-gated channel subfamily H member 2 isoform d | 1 | 0 | 0 | 1 |
| geminin | 1 | 0 | 0 | 1 |
| DNA polymerase kappa isoform 1 | 1 | 0 | 0 | 1 |
| Carbonic anhydrase 1 | 0 | 2 | 0 | 2 |
| Carbonic anhydrase 2 | 0 | 2 | 0 | 2 |
| Carbonic anhydrase 4 | 0 | 2 | 0 | 2 |
| Carbonic anhydrase | 0 | 2 | 0 | 2 |
| Sodium/iodide cotransporter | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 15 | 0 | 1 | 0 | 1 |
| thioredoxin reductase | 1 | 0 | 0 | 1 |
| PPM1D protein | 1 | 0 | 0 | 1 |
| aldehyde dehydrogenase 1 family, member A1 | 1 | 0 | 0 | 1 |
| regulator of G-protein signaling 4 | 1 | 0 | 0 | 1 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 2 | 0 | 0 | 2 |
| EWS/FLI fusion protein | 1 | 0 | 0 | 1 |
| pregnane X nuclear receptor | 2 | 0 | 0 | 2 |
| cytochrome P450 2D6 | 2 | 0 | 0 | 2 |
| arylsulfatase A | 1 | 0 | 0 | 1 |
| aryl hydrocarbon receptor | 2 | 0 | 0 | 2 |
| karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b | 0 | 0 | 1 | 1 |
| nuclear receptor subfamily 1, group I, member 2 | 1 | 0 | 0 | 1 |
| Bloom syndrome protein isoform 1 | 1 | 0 | 0 | 1 |
| cellular tumor antigen p53 isoform a | 2 | 0 | 0 | 2 |
| cytochrome P450 3A4 isoform 1 | 2 | 0 | 0 | 2 |
| M-phase phosphoprotein 8 | 1 | 0 | 0 | 1 |
| muscleblind-like protein 1 isoform 1 | 1 | 0 | 0 | 1 |
| muscarinic acetylcholine receptor M1 | 1 | 0 | 0 | 1 |
| neuropeptide S receptor isoform A | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | 2 | 0 | 0 | 2 |
| ATP-binding cassette sub-family C member 3 | 0 | 1 | 0 | 1 |
| Multidrug resistance-associated protein 4 | 0 | 1 | 0 | 1 |
| Bile salt export pump | 0 | 1 | 0 | 1 |
| Bile salt export pump | 0 | 2 | 0 | 2 |
| Interferon beta | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit delta | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 2 | 0 | 0 | 2 |
| GABA theta subunit | 2 | 0 | 0 | 2 |
| Canalicular multispecific organic anion transporter 1 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | 2 | 0 | 0 | 2 |
| ATP-dependent phosphofructokinase | 1 | 0 | 0 | 1 |
| Sphingosine kinase 2 | 0 | 2 | 0 | 2 |
| Sphingosine kinase 1 | 0 | 1 | 0 | 1 |
| Chain A, Lysr-type Regulatory Protein | 0 | 0 | 1 | 1 |
| Chain A, Lysr-type Regulatory Protein | 0 | 0 | 1 | 1 |
| Chain A, Lysr-type Regulatory Protein | 0 | 0 | 1 | 1 |
| Chain A, 146aa long hypothetical transcriptional regulator | 0 | 0 | 1 | 1 |
| Chain A, Anthranilate phosphoribosyltransferase | 0 | 1 | 0 | 1 |
| Chain A, Anthranilate phosphoribosyltransferase | 0 | 1 | 0 | 1 |
| Chain A, Anthranilate phosphoribosyltransferase | 0 | 1 | 0 | 1 |
| Chain B, Anthranilate phosphoribosyltransferase | 0 | 1 | 0 | 1 |
| Chain C, Anthranilate phosphoribosyltransferase | 0 | 1 | 0 | 1 |
| Chain A, Anthranilate phosphoribosyltransferase | 0 | 1 | 0 | 1 |
| Anthranilate phosphoribosyltransferase | 0 | 1 | 0 | 1 |
| Carbonic anhydrase | 0 | 1 | 0 | 1 |
| Mu-type opioid receptor | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 5A, mitochondrial | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 9 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 5B, mitochondrial | 0 | 1 | 0 | 1 |
| Nuclear receptor ROR-gamma | 2 | 0 | 0 | 2 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 1 | 0 | 0 | 1 |
| Chain A, Methionine aminopeptidase | 0 | 1 | 0 | 1 |
| Chain A, 2-oxoglutarate Oxygenase | 1 | 0 | 0 | 1 |
| BRCA1 | 1 | 0 | 0 | 1 |
| pregnane X receptor | 1 | 0 | 0 | 1 |
| ATAD5 protein, partial | 1 | 0 | 0 | 1 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 1 | 0 | 0 | 1 |
| thyroid stimulating hormone receptor | 1 | 0 | 0 | 1 |
| P53 | 1 | 0 | 0 | 1 |
| pyruvate kinase | 1 | 0 | 0 | 1 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | 1 | 0 | 0 | 1 |
| cytochrome P450 2D6 isoform 1 | 1 | 0 | 0 | 1 |
| NPC intracellular cholesterol transporter 1 precursor | 1 | 0 | 0 | 1 |
| cytochrome P450 2C19 precursor | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform a | 1 | 0 | 0 | 1 |
| histone deacetylase 9 isoform 3 | 1 | 0 | 0 | 1 |
| ras-related protein Rab-9A | 1 | 0 | 0 | 1 |
| urokinase-type plasminogen activator precursor | 1 | 0 | 0 | 1 |
| plasminogen precursor | 1 | 0 | 0 | 1 |
| urokinase plasminogen activator surface receptor precursor | 1 | 0 | 0 | 1 |
| peripheral myelin protein 22 | 1 | 0 | 0 | 1 |
| Integrin beta-3 | 1 | 0 | 0 | 1 |
| Cytochrome P450 1A2 | 0 | 1 | 0 | 1 |
| Integrin alpha-IIb | 1 | 0 | 0 | 1 |
| Methionine aminopeptidase | 0 | 1 | 0 | 1 |
| Cytochrome P450 2C9 | 0 | 1 | 0 | 1 |
| Endothelin receptor type B | 1 | 0 | 0 | 1 |
| Endothelin-1 receptor | 1 | 0 | 0 | 1 |
| Methionine aminopeptidase 2 | 0 | 1 | 0 | 1 |
| Methionine aminopeptidase 1 | 0 | 1 | 1 | 2 |
| Peptidyl-prolyl cis-trans isomerase FKBP1A | 0 | 0 | 1 | 1 |
| Fatty-acid amide hydrolase 1 | 0 | 1 | 0 | 1 |
| Reverse transcriptase/RNaseH | 0 | 1 | 0 | 1 |
| Multidrug and toxin extrusion protein 1 | 0 | 1 | 0 | 1 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |