Uterine Rupture

A complete separation or tear in the wall of the UTERUS with or without expulsion of the FETUS. It may be due to injuries, multiple pregnancies, large fetus, previous scarring, or obstruction.

Synonym
Uterine Rupture

Excerpt	Reference
"Uterine rupture is still a common problem in developing countries although even here the incidence varies from urban to rural settings."	( Balakrishnan, S; Balasundram, G; Rachagan, SP; Raman, S, 1991)
"The uterine rupture is assumed to have occurred during the 2nd course of gemeprost."	( Evans, AS; Wiener, JJ, 1990)
"A case of uterine rupture is presented following induction of second-trimester abortion using oxytocin and prostaglandin F2 alpha."	( Hemmingsson, E; Malmström, H, 1984)
"Uterine rupture is an uncommon complication of midtrimester abortion, occurring more frequently in the older multiparous patient and with the use of high doses of oxytocic agents."	( Graham, D, 1982)
"The diagnosis of uterine rupture is aided by the identification of risk factors, such as oxytocin administration."	( Bristow, RE; Bruni, R; Hsu, CD; Iriye, BK; Johnson, TR, 1994)
"Uterine rupture is a catastrophic obstetric complication, most often associated with a preexisting cesarean section scar."	( Botosneano, A; Hochner-Celnikier, D; Shimonovitz, S, 2000)
"Uterine rupture is a serious and often tragic complication that is life threatening to both mother and child."	( Abu-Musa, A; El-Hajj, MI; Khabbaz, AY; Nassar, AH; Seoud, M; Usta, IM, 2001)
"Uterine rupture is commonly associated with vaginal birth after caesarean section, although the absolute risk varies according to previous obstetric history, gestational age, and induction of labour."	( Murphy, DJ, 2006)
"Uterine rupture is a true obstetrical emergency."	( Mazzone, ME; Woolever, J, 2006)
"Spontaneous uterine rupture is a life-threatening obstetrical emergency encountered infrequently in the Emergency Department."	( Dane, B; Dane, C, 2009)
"Child birth after uterine rupture is not to be recommended routinely."	( Al Fadhli, R; Al Harmi, J; Al Jassar, W; Chibber, R; El-Saleh, E, 2010)
"Although uterine rupture is rare, its association with epidural analgesia and augmentation of labour with oxytocin in multipara should be considered."	( Krebs, L; Mortensen, LH; Thisted, DLA, 2015)
"Uterine rupture is an uncommon complication following termination of pregnancy and is usually accompanied by severe lower abdominal pain and shock caused by intra-abdominal hemorrhage."	( Jiang, Q; Liu, F; Lv, YE; Yang, L; Zheng, Y, 2016)
"Complete uterine rupture is a rare peripartum complication associated with a catastrophic outcome."	( Al-Zirqi, I; Daltveit, AK; Forsén, L; Stray-Pedersen, B; Vangen, S, 2017)
"Uterine rupture is a complication that can be eliminated under conditions of best obstetric practice."	( Belley-Priso, E; Egbe, TO; Halle-Ekane, GE; Nyemb, JE; Tchente, CN, 2016)
"Uterine rupture is a rare complication in second trimester termination of pregnancy (TOP) with an overall incidence of up to 1."	( Daniel Seow Choon, K; Eek Chaw, T; Hester Chang Qi, QL; Kok Hian, T; Mor Jack, NG; Wan Shi, T, 2018)
"Uterine rupture is a rare complication of second-trimester medical abortion with gemeprost."	( Di Carlo, C; Ferrara, C; Morra, I; Perriera, L; Saccone, G; Sansone, A; Sglavo, G, 2019)
"Uterine rupture is a rare event during cervical ripening and labor induction with PGE2."	( Chiossi, G; D'Amico, R; Facchinetti, F; Laghi, V; Sampogna, V; Tramontano, AL, 2021)
"Uterine rupture is a grave obstetric emergency with high maternal and neonatal morbidity and mortality."	( Abrar, S; Abrar, T; Naqvi, SA; Sayyed, E, 2022)
"Uterine rupture is a preventable obstetric emergency associated with high fetomaternal morbidity and mortality."	( Abrar, S; Abrar, T; Naqvi, SA; Sayyed, E, 2022)

Excerpt	Reference
"Fear of uterine rupture has led to the widespread practice of 'Once a section, always a section'."	( Burke, G; Kehoe, JT; Magani, IM; Meehan, FP, 1990)
" Higher risks of uterine rupture have been reported among women attempting vaginal birth after caesarean (VBAC) particularly following induction with prostaglandins, compared with women who do not labour."	( Chan, A; Cornes, S; Cull, V; Dekker, GA; Gee, V; Halliday, J; King, JF; Luke, CG; O'Neill, M; Priest, K; Riley, M; Snell, M, 2010)

Excerpt	Reference
"As uterine rupture may affect as many as 11/1000 women with 1 prior cesarean birth and 5/10."	( Chiossi, G; D'Amico, R; Facchinetti, F; Laghi, V; Sampogna, V; Tramontano, AL, 2021)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	163 (37.30)	23.3326
1990's	69 (15.79)	12.5806
2000's	107 (24.49)	18.1394
2010's	78 (17.85)	28.8240
2020's	20 (4.58)	9.53

Drug	Relationship Strength	Studies	Trials
gamma-aminobutyric acid	low	1	0
salicylic acid	low	2	0
lactic acid	low	1	0
nitrous oxide	low	2	0
pyridoxine	low	1	0
urea	low	2	0
ethacridine	low	5	0
bupivacaine	low	3	0
chlorpromazine	low	1	0
diclofenac	low	1	0
droperidol	low	1	0
fentanyl	low	5	0
halothane	low	2	0
lidocaine	low	1	0
isoxsuprine	low	1	0
meperidine	low	2	0
metaproterenol	low	1	0
metronidazole	low	2	0
phenylbutazone	low	1	0
propofol	low	1	0
tolazoline	low	1	0
tranexamic acid	low	1	0
trimethadione	low	1	0
prednisolone	low	1	0
prednisone	low	1	0
pentylenetetrazole	low	1	0
tromethamine	low	1	0
thiophenes	low	1	0
methylergonovine	low	2	0
acridines	low	1	0
ephedrine	low	2	0
betamethasone	low	1	0
erythromycin	low	1	0
technetium	low	1	0
gadolinium	low	1	0
ferrous sulfate	low	1	0
barium sulfate	low	1	0
clonixin	low	1	0
cetylpyridinium chloride anhydrous	low	2	0
4-methoxyamphetamine	low	1	0
flunixin meglumine	low	1	0
mifepristone	low	20	0
duloxetine hydrochloride	low	1	0
tebuconazole	low	1	0
nsc-172755	low	2	0
fibrinogen	low	6	0
methotrexate	low	9	0
paromomycin	low	1	0
17 alpha-hydroxyprogesterone caproate	low	1	0
cortisone	low	1	0
fibrin	low	2	0
oxytocin	medium	180	10
pentazocine	low	1	0
ergonovine	low	3	0
retinol	low	1	0
cocaine	low	4	0
diethylstilbestrol	low	4	0
dimemorfan	low	1	0
dinoprostone	medium	54	5
dinoprost	low	7	0
vitamin k semiquinone radical	low	1	0
alprostadil	low	14	0
hemabate	low	1	0
carboprost	low	4	0
gemeprost	low	13	0
misoprostol	medium	88	4
prostaglandin f2 methyl ester	low	1	0
phenylephrine hydrochloride	low	1	0
morphine	low	2	0
sulprostone	low	3	0
cesium	low	1	0
levallorphan	low	1	0
pregabalin	low	1	0
radium	low	2	0
morphinans	low	1	0
pituitrin	low	2	0
clove	low	2	0
ascorbic acid	low	1	0
warfarin	low	1	0
rolitetracycline	low	1	0
exudates	low	3	0
folic acid	low	1	0

Protein Targets (918)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, Ferritin light chain	10	0	0	10
glp-1 receptor, partial	10	0	0	10
phosphopantetheinyl transferase	8	0	0	8
hypoxia-inducible factor 1 alpha subunit	4	0	0	4
RAR-related orphan receptor gamma	18	0	0	18
SMAD family member 2	9	0	0	9
Fumarate hydratase	4	0	0	4
SMAD family member 3	9	0	0	9
TDP1 protein	29	0	0	29
GLI family zinc finger 3	26	0	0	26
Microtubule-associated protein tau	16	0	0	16
AR protein	34	0	0	34
Smad3	5	0	0	5
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	8	0	0	8
estrogen receptor 2 (ER beta)	12	0	0	12
nuclear receptor subfamily 1, group I, member 3	15	0	0	15
progesterone receptor	15	0	0	15
cytochrome P450 family 3 subfamily A polypeptide 4	16	0	0	16
glucocorticoid receptor [Homo sapiens]	23	0	0	23
retinoic acid nuclear receptor alpha variant 1	19	0	0	19
retinoid X nuclear receptor alpha	14	0	0	14
estrogen-related nuclear receptor alpha	27	0	0	27
farnesoid X nuclear receptor	11	0	0	11
pregnane X nuclear receptor	21	0	0	21
estrogen nuclear receptor alpha	41	0	0	41
G	9	0	0	9
cytochrome P450 2D6	12	0	0	12
polyprotein	4	0	0	4
67.9K protein	6	0	0	6
bromodomain adjacent to zinc finger domain 2B	4	0	0	4
peroxisome proliferator-activated receptor delta	11	0	0	11
peroxisome proliferator activated receptor gamma	16	0	0	16
vitamin D (1,25- dihydroxyvitamin D3) receptor	20	0	0	20
IDH1	9	0	0	9
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	14	0	0	14
thyroid stimulating hormone receptor	9	0	0	9
activating transcription factor 6	10	0	0	10
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	7	0	0	7
v-jun sarcoma virus 17 oncogene homolog (avian)	12	0	0	12
Histone H2A.x	10	0	0	10
Caspase-7	2	0	0	2
vitamin D3 receptor isoform VDRA	17	0	0	17
nuclear factor erythroid 2-related factor 2 isoform 2	8	0	0	8
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	6	0	0	6
caspase-3	2	0	0	2
thyroid hormone receptor beta isoform 2	19	0	0	19
heat shock protein beta-1	9	0	0	9
huntingtin isoform 2	2	0	0	2
nuclear factor erythroid 2-related factor 2 isoform 1	20	0	0	20
nuclear receptor ROR-gamma isoform 1	11	0	0	11
geminin	22	0	0	22
survival motor neuron protein isoform d	10	0	0	10
replicative DNA helicase	0	0	0	2
recombinase A	0	0	2	2
lamin isoform A-delta10	24	0	0	24
neuropeptide S receptor isoform A	6	0	0	6
Voltage-dependent calcium channel gamma-2 subunit	10	0	0	10
Interferon beta	12	0	0	12
HLA class I histocompatibility antigen, B alpha chain	9	0	0	9
Cellular tumor antigen p53	24	0	0	24
Glutamate receptor 2	10	0	0	10
Alpha-synuclein	5	1	0	6
Spike glycoprotein	11	1	1	13
Guanine nucleotide-binding protein G	2	0	0	2
Inositol hexakisphosphate kinase 1	9	0	0	9
cytochrome P450 2C9, partial	9	0	0	9
5-hydroxytryptamine receptor 2C	0	7	2	10
5-hydroxytryptamine receptor 2A	0	7	2	9
5-hydroxytryptamine receptor 1A	0	12	1	13
5-hydroxytryptamine receptor 1B	0	11	1	12
5-hydroxytryptamine receptor 1D	0	2	1	3
5-hydroxytryptamine receptor 1F	0	2	1	3
5-hydroxytryptamine receptor 2B	0	6	2	8
5-hydroxytryptamine receptor 6	0	1	1	2
Sodium-dependent serotonin transporter	0	7	1	8
Sodium-dependent serotonin transporter	0	5	0	6
5-hydroxytryptamine receptor 7	0	3	1	4
5-hydroxytryptamine receptor 5A	0	1	1	2
5-hydroxytryptamine receptor 5B	0	1	1	2
5-hydroxytryptamine receptor 3A	0	1	1	2
5-hydroxytryptamine receptor 4	0	1	1	2
5-hydroxytryptamine receptor 3B	0	1	1	2
thioredoxin reductase	16	0	0	16
aldehyde dehydrogenase 1 family, member A1	21	0	0	21
alpha-galactosidase	3	0	0	3
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	9	0	0	9
flap endonuclease 1	6	0	0	6
DNA polymerase iota isoform a (long)	9	0	0	9
DNA topoisomerase 2-alpha	0	0	0	1
Acetylcholinesterase	0	4	0	4
ATP-binding cassette sub-family C member 3	0	12	0	12
Multidrug resistance-associated protein 4	0	12	0	16
Bile salt export pump	0	30	0	30
Thromboxane-A synthase	0	2	0	2
Prostaglandin E2 receptor EP3 subtype	0	2	0	2
Prostaglandin E2 receptor EP4 subtype	0	2	1	3
Prostaglandin E2 receptor EP1 subtype	0	2	0	2
Prostacyclin receptor	0	4	2	6
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Solute carrier organic anion transporter family member 2A1	0	1	0	4
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Prostaglandin E2 receptor EP2 subtype	0	2	1	3
Canalicular multispecific organic anion transporter 1	0	12	0	12
Solute carrier organic anion transporter family member 2A1	0	1	0	4
Solute carrier organic anion transporter family member 2B1	0	2	0	2
Solute carrier organic anion transporter family member 3A1	0	0	0	1
glucocerebrosidase	2	0	0	2
DNA polymerase kappa isoform 1	6	0	0	6
histone acetyltransferase KAT2A isoform 1	10	0	0	10
Atrial natriuretic peptide receptor 3	0	1	0	1
Type-1A angiotensin II receptor	0	2	1	3
Type-1 angiotensin II receptor	0	0	1	1
Type-1B angiotensin II receptor	0	2	0	2
Type-1 angiotensin II receptor	0	2	2	4
Type-2 angiotensin II receptor	0	2	0	2
Type-2 angiotensin II receptor	0	2	0	2
Chain A, Hyaluronidase, phage associated	0	1	0	1
acetylcholinesterase	11	0	0	11
thioredoxin glutathione reductase	4	0	0	4
euchromatic histone-lysine N-methyltransferase 2	19	0	0	19
chromobox protein homolog 1	18	0	0	18
lethal(3)malignant brain tumor-like protein 1 isoform I	1	0	0	1
lethal factor (plasmid)	5	0	0	5
Polyphenol oxidase 2	0	2	0	3
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	1	0	1
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	1	0	1
Alpha-2B adrenergic receptor	0	13	1	14
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
pregnane X receptor	7	0	0	7
aryl hydrocarbon receptor	5	0	0	5
nuclear receptor subfamily 1, group I, member 2	3	0	0	3
thyroid hormone receptor beta isoform a	7	0	0	7
galanin receptor type 3	0	1	0	1
Glucocorticoid receptor	1	14	4	26
Glycine receptor subunit alpha-1	0	14	0	14
Glycine receptor subunit beta	0	14	0	14
Glycine receptor subunit alpha-2	0	14	0	14
Glycine receptor subunit alpha-3	0	14	0	14
ORF73	0	0	1	1
Potassium channel subfamily K member 3	0	2	0	2
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	2	1	3
Potassium channel subfamily K member 9	0	1	0	1
USP1 protein, partial	13	0	0	13
caspase 7, apoptosis-related cysteine protease	5	0	0	5
caspase-3	5	0	0	5
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	1	0	0	1
thyrotropin-releasing hormone receptor	1	0	0	1
mitogen-activated protein kinase 1	9	0	0	9
Caspase-2	0	0	1	1
Inositol monophosphatase 1	2	0	0	2
ATPase family AAA domain-containing protein 5	6	0	0	6
Ataxin-2	7	0	0	7
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	8	0	0	8
Proteasome subunit beta type-11	0	0	0	1
ATAD5 protein, partial	10	0	0	10
NFKB1 protein, partial	2	0	0	2
Thrombopoietin	1	0	0	1
NADPH oxidase 1	0	1	0	1
Snq2p	0	0	0	1
Adenylate cyclase type 1	0	2	0	2
Spike glycoprotein	0	1	1	2
Replicase polyprotein 1ab	0	1	1	2
cytochrome P450 2D6 isoform 1	3	0	0	3
cellular tumor antigen p53 isoform a	4	0	0	4
D(1A) dopamine receptor	8	0	0	8
potassium voltage-gated channel subfamily H member 2 isoform d	9	0	0	9
histone deacetylase 9 isoform 3	2	0	0	2
atrial natriuretic peptide receptor 2 precursor	2	0	0	2
ras-related protein Rab-9A	2	0	0	2
serine/threonine-protein kinase mTOR isoform 1	3	0	0	3
peripheral myelin protein 22	16	0	0	16
cytochrome P450 3A4 isoform 1	10	0	0	10
M-phase phosphoprotein 8	6	0	0	6
muscarinic acetylcholine receptor M1	4	0	0	4
Gamma-aminobutyric acid receptor subunit pi	10	3	1	14
Proteasome subunit alpha type-7	0	0	0	1
Solute carrier family 22 member 1	0	4	0	6
Polyunsaturated fatty acid lipoxygenase ALOX15B	2	0	0	2
Transmembrane protease serine 2	0	1	1	2
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Transient receptor potential cation channel subfamily V member 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	3	0	3
Bile salt export pump	0	5	0	5
5-hydroxytryptamine receptor 4	0	12	0	12
Epidermal growth factor receptor	0	1	0	1
Albumin	0	3	4	7
Albumin	0	0	2	2
Major prion protein	0	0	1	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	2	0	2
Receptor tyrosine-protein kinase erbB-2	0	1	0	1
Major prion protein	0	0	1	1
Integrin beta-3	4	0	0	4
Cytochrome P450 1A2	0	0	1	1
Tyrosine-protein kinase Fyn	0	3	0	3
Procathepsin L	0	1	1	2
Aldo-keto reductase family 1 member B1	0	6	0	6
Muscarinic acetylcholine receptor M2	0	2	0	2
Muscarinic acetylcholine receptor M4	0	4	0	4
ATP-dependent translocase ABCB1	0	6	0	7
Muscarinic acetylcholine receptor M1	0	3	0	3
Muscarinic acetylcholine receptor M3	0	2	0	2
Muscarinic acetylcholine receptor M4	0	2	0	2
Integrin alpha-IIb	4	0	0	4
5-hydroxytryptamine receptor 1A	0	2	1	3
Muscarinic acetylcholine receptor M5	0	2	0	2
Muscarinic acetylcholine receptor M5	0	4	0	4
Alpha-2A adrenergic receptor	0	11	2	13
Replicase polyprotein 1a	0	1	1	2
Replicase polyprotein 1ab	0	1	1	2
Replicase polyprotein 1ab	0	1	1	2
Cys-loop ligand-gated ion channel	0	1	0	1
Calmodulin-1	0	2	1	3
Replicase polyprotein 1ab	0	1	1	2
Cytochrome P450 2D6	0	2	1	3
Muscarinic acetylcholine receptor M2	0	2	0	2
Muscarinic acetylcholine receptor M1	0	4	0	4
Cytochrome P450 2C9	0	7	0	8
Polyunsaturated fatty acid lipoxygenase ALOX15	0	5	0	5
Angiotensin-converting enzyme	0	4	0	4
D(2) dopamine receptor	0	13	0	14
Gamma-aminobutyric acid receptor subunit beta-1	10	3	1	14
Alpha-1B adrenergic receptor	0	9	2	11
Sphingomyelin phosphodiesterase	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	10	3	1	14
Gamma-aminobutyric acid receptor subunit gamma-2	10	3	2	15
Alpha-2C adrenergic receptor	0	7	1	8
D	0	4	0	4
D(3) dopamine receptor	0	2	0	2
Alpha-2B adrenergic receptor	0	7	1	8
Gamma-aminobutyric acid receptor subunit alpha-5	10	3	1	14
Gamma-aminobutyric acid receptor subunit alpha-3	10	3	1	14
D(2) dopamine receptor	0	1	0	1
Muscarinic acetylcholine receptor M3	0	4	0	4
Proteasome subunit beta type-1	0	0	0	1
Substance-K receptor	0	4	0	4
D(1A) dopamine receptor	0	11	0	12
D(4) dopamine receptor	0	5	0	6
D(1B) dopamine receptor	0	1	0	2
Adenylate cyclase type 3	0	2	0	2
Alpha-2C adrenergic receptor	0	7	1	8
UDP-glucuronosyltransferase 1A4	0	1	0	2
Alpha-2A adrenergic receptor	0	7	1	8
Gamma-aminobutyric acid receptor subunit gamma-1	10	3	1	14
Gamma-aminobutyric acid receptor subunit alpha-2	10	3	1	14
Alpha-1D adrenergic receptor	0	7	2	9
Sodium-dependent noradrenaline transporter	0	11	0	11
Sodium-dependent dopamine transporter	0	5	0	5
Histamine H2 receptor	0	2	0	2
Alpha-1D adrenergic receptor	0	6	1	7
D(1B) dopamine receptor	0	2	0	2
Proteasome subunit alpha type-1	0	0	0	1
Proteasome subunit alpha type-2	0	0	0	1
Proteasome subunit alpha type-3	0	0	0	1
Proteasome subunit alpha type-4	0	0	0	1
Adenylate cyclase type 2	0	2	0	2
Adenylate cyclase type 4	0	2	0	2
Proteasome subunit beta type-8	0	0	0	1
Proteasome subunit beta type-9	0	0	0	1
Proteasome subunit alpha type-5	0	0	0	1
Proteasome subunit beta type-4	0	0	0	1
Proteasome subunit beta type-6	0	0	0	1
Proteasome subunit beta type-5	0	0	0	1
5-hydroxytryptamine receptor 2A	0	12	1	15
5-hydroxytryptamine receptor 2C	0	14	0	15
Gamma-aminobutyric acid receptor subunit alpha-4	10	3	1	14
Gamma-aminobutyric acid receptor subunit gamma-3	10	3	1	14
Trypanothione reductase	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-6	10	3	1	14
D(4) dopamine receptor	0	2	0	2
Histamine H1 receptor	0	2	1	3
Melanocortin receptor 4	0	2	0	2
Melanocortin receptor 5	0	2	0	2
Pleiotropic ABC efflux transporter of multiple drugs	0	1	0	2
5-hydroxytryptamine receptor 7	0	2	0	2
Histamine H1 receptor	0	6	0	6
Mu-type opioid receptor	0	13	3	17
Glutamate receptor ionotropic, NMDA 1	0	2	1	3
D(3) dopamine receptor	0	12	0	13
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	2	0	2
Adenylate cyclase type 8	0	2	0	2
Proteasome subunit beta type-10	0	0	0	1
Delta-type opioid receptor	0	9	1	11
Kappa-type opioid receptor	0	12	1	14
5-hydroxytryptamine receptor 2B	0	14	1	16
Melanocortin receptor 3	0	2	0	2
Alpha-1A adrenergic receptor	0	10	2	12
Histamine H2 receptor	5	0	1	7
Proteasome subunit beta type-3	0	0	0	1
Proteasome subunit beta type-2	0	0	0	1
D(1A) dopamine receptor	3	0	0	3
5-hydroxytryptamine receptor 6	0	9	0	9
5-hydroxytryptamine receptor 7	0	3	0	3
Cytochrome P450 2J2	0	4	0	4
Gastrin/cholecystokinin type B receptor	0	1	0	1
Proteasome subunit alpha type-6	0	0	1	2
D(2) dopamine receptor	0	5	0	6
Calmodulin	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-1	10	3	2	15
Gamma-aminobutyric acid receptor subunit beta-3	10	3	1	14
Gamma-aminobutyric acid receptor subunit beta-2	10	3	2	15
Aldehyde oxidase 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	2	1	3
Glutamate receptor ionotropic, NMDA 2B	0	2	1	3
Glutamate receptor ionotropic, NMDA 2C	0	2	1	3
Sodium channel protein type 7 subunit alpha	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	3	0	3
Sodium-dependent dopamine transporter	0	6	0	6
Adenylate cyclase type 6	0	2	0	2
Adenylate cyclase type 5	0	2	0	2
Glutamate receptor ionotropic, NMDA 1	0	1	0	1
Aldehyde oxidase	0	3	0	3
Potassium voltage-gated channel subfamily H member 2	0	11	0	11
Glutamate receptor ionotropic, NMDA 2A	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1C	0	4	0	4
Sodium channel protein type 5 subunit alpha	0	2	0	2
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Sodium channel protein type 9 subunit alpha	0	2	0	2
Glutamate receptor ionotropic, NMDA 2D	0	2	1	3
Nuclear receptor subfamily 3 group C member 3	0	4	0	4
Adenylyl cyclase 7	0	2	0	2
Proteasome subunit alpha-type 8	0	0	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	2	1	3
GABA theta subunit	10	3	1	14
D	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Proteasome subunit beta type-7	0	0	0	1
Sigma non-opioid intracellular receptor 1	0	11	0	11
Angiotensin-converting enzyme 2	0	1	1	2
Gamma-aminobutyric acid receptor subunit epsilon	10	3	1	14
Sodium channel protein type 3 subunit alpha	0	2	0	2
Glutamate receptor ionotropic, NMDA 3A	0	2	1	3
Sodium channel protein type 11 subunit alpha	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	1	0	1
Histamine H3 receptor	0	1	0	1
Sodium channel protein type 10 subunit alpha	0	1	0	1
Luciferase	8	0	0	8
serine/threonine-protein kinase PLK1	3	0	0	3
UDP-glucuronosyltransferase 2B7	0	1	0	3
UDP-glucuronosyltransferase 1A3	0	0	0	3
Dihydroorotate dehydrogenase (quinone), mitochondrial	0	1	0	1
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain H, Fab M82G2, Heavy chain	0	0	1	1
Chain L, Fab M82G2, Light chain	0	0	1	1
Chain H, Fab M82g2, Heavy Chain	0	0	1	1
Chain L, Fab M82g2, Light Chain	0	0	1	1
Gamma-aminobutyric acid receptor subunit pi	0	2	0	2
Gamma-aminobutyric acid receptor subunit delta	0	2	0	2
Amyloid-beta precursor protein	0	2	0	2
Fatty acid-binding protein, heart	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Tryptophan 5-hydroxylase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	3	2	5
Gamma-aminobutyric acid receptor subunit beta-1	0	2	2	4
Gamma-aminobutyric acid receptor subunit gamma-2	0	3	2	5
Liver carboxylesterase 1	0	1	0	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	3	2	5
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	2	4
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	2	4
Lysosomal Pro-X carboxypeptidase	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	2	4
Gamma-aminobutyric acid receptor subunit beta-2	0	2	2	4
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	2	4
Gamma-aminobutyric acid receptor subunit epsilon	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Leukotriene B4 receptor 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	2	4
Sodium-dependent dopamine transporter	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	0	2
Leukotriene B4 receptor 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	2	0	2
Transporter	0	2	0	2
Chain A, HADH2 protein	9	0	0	9
Chain B, HADH2 protein	9	0	0	9
endonuclease IV	1	0	0	1
dopamine D1 receptor	6	0	0	6
GLS protein	11	0	0	11
regulator of G-protein signaling 4	10	0	0	10
peripheral myelin protein 22 isoform 1	1	0	0	1
atrial natriuretic peptide receptor 1 precursor	1	0	0	1
Sex hormone-binding globulin	0	0	1	1
Corticosteroid-binding globulin	0	2	0	2
Potassium voltage-gated channel subfamily A member 1	0	0	1	1
TAR DNA-binding protein 43	7	0	0	7
Multidrug and toxin extrusion protein 1	0	5	0	5
Aldo-keto reductase family 1 member B10	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	1	0	3
Prostaglandin G/H synthase 1	0	2	0	2
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Dihydrofolate reductase	0	3	0	4
Cytochrome c oxidase subunit 2	0	1	0	1
Carbonic anhydrase 1	0	5	0	5
Carbonic anhydrase 2	0	5	2	7
Fatty acid-binding protein, liver	0	2	0	2
Transthyretin	0	0	1	3
Prostaglandin G/H synthase 1	0	3	0	3
Cytochrome P450 3A4	0	5	2	7
Interleukin-8	0	1	0	1
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	1	0	1
Fatty acid-binding protein, intestinal	0	1	0	1
Aldo-keto reductase family 1 member B1	0	3	0	3
UDP-glucuronosyltransferase 1-6	0	2	0	2
UDP-glucuronosyltransferase 1A1	0	2	0	2
Prostaglandin G/H synthase 1	0	6	0	6
Sodium- and chloride-dependent GABA transporter 1	0	3	0	3
C-X-C chemokine receptor type 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	3	0	3
Sodium- and chloride-dependent GABA transporter 3	0	3	0	3
Prostaglandin G/H synthase 2	0	5	0	5
Prostaglandin G/H synthase 2	0	2	0	2
UDP-glucuronosyltransferase 2B10	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	3	0	3
Prostaglandin G/H synthase 2	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Carbonic anhydrase 9	0	2	0	2
Solute carrier family 22 member 6	0	2	0	5
Prostaglandin G/H synthase 1	0	2	0	2
Carbonic anhydrase 4	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
UDP-glucuronosyltransferase 1A7	0	1	0	1
UDP-glucuronosyltransferase 1A10	0	1	0	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	9	0	0	9
Chain A, JmjC domain-containing histone demethylation protein 3A	3	0	0	3
interleukin 8	2	0	0	2
15-lipoxygenase, partial	3	0	0	3
thyroid stimulating hormone receptor	9	0	0	9
ubiquitin carboxyl-terminal hydrolase 2 isoform a	3	0	0	3
histone-lysine N-methyltransferase 2A isoform 2 precursor	2	0	0	2
high affinity choline transporter 1 isoform a	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	0	0	1
Nuclear receptor subfamily 1 group I member 2	0	1	1	2
Estrogen receptor	1	6	2	9
Beta-1 adrenergic receptor	0	4	2	6
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Adenosine receptor A3	0	2	0	2
Androgen receptor	0	6	0	6
Adenosine receptor A2a	0	2	0	2
Adenosine receptor A1	0	2	0	2
Vasopressin V1a receptor	0	4	1	5
Nuclear receptor ROR-gamma	4	0	0	4
Estrogen-related receptor gamma	0	0	1	1
Disintegrin and metalloproteinase domain-containing protein 17	2	0	0	2
UDP-glucose 4-epimerase	0	1	0	1
Mitogen-activated protein kinase 14	0	2	0	2
Estrogen receptor beta	1	6	2	9
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	1	0	2
Cysteinyl leukotriene receptor 1	0	2	0	2
Solute carrier family 22 member 2	0	0	0	2
Prostaglandin G/H synthase 2	0	1	0	1
Thromboxane A2 receptor	0	1	1	2
Prostaglandin E2 receptor EP1 subtype	0	3	2	5
Prostaglandin E2 receptor EP4 subtype	0	3	1	4
Prostaglandin F2-alpha receptor	0	2	0	2
Prostaglandin F2-alpha receptor	0	2	2	4
Prostaglandin E2 receptor EP3 subtype	0	3	2	5
Prostaglandin E2 receptor EP2 subtype	0	3	1	4
Prostaglandin F2-alpha receptor	0	0	1	1
Prostaglandin D2 receptor	0	1	0	1
Solute carrier family 22 member 7	0	0	0	3
Solute carrier family 22 member 8	0	2	0	5
Solute carrier organic anion transporter family member 2A1	0	1	0	1
Solute carrier family 22 member 11	0	0	0	3
Solute carrier family 22 member 7	0	0	0	2
Chain A, Cruzipain	6	0	0	6
prostaglandin E2 receptor EP2 subtype	1	0	0	1
Solute carrier organic anion transporter family member 1A5	0	0	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier family 22 member 20	0	3	0	3
Solute carrier family 22 member 6	0	3	0	3
Solute carrier family 22 member 7	0	0	0	1
Solute carrier organic anion transporter family member 1B2	0	0	0	1
Chain A, Beta-lactamase	8	0	0	8
Chain A, 2-oxoglutarate Oxygenase	8	0	0	8
cytochrome P450 2C9 precursor	3	0	0	3
DNA polymerase beta	4	0	0	4
N-acetyltransferase Eis	0	1	0	1
importin subunit beta-1 isoform 1	2	0	0	2
snurportin-1	2	0	0	2
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
urokinase-type plasminogen activator precursor	2	0	0	2
plasminogen precursor	2	0	0	2
urokinase plasminogen activator surface receptor precursor	2	0	0	2
ATP-dependent translocase ABCB1	0	4	0	4
ATP-dependent translocase ABCB1	0	4	1	5
Motilin receptor	0	0	1	1
acid sphingomyelinase	3	0	0	3
low molecular weight phosphotyrosine protein phosphatase isoform c	0	1	0	1
streptokinase A precursor	0	0	1	1
Motilin receptor	0	1	1	2
Rap guanine nucleotide exchange factor 3	4	0	0	4
30S ribosomal protein S6	0	2	1	3
30S ribosomal protein S7	0	2	1	3
50S ribosomal protein L15	0	2	1	3
60 kDa chaperonin	0	1	0	1
50S ribosomal protein L10	0	2	1	3
50S ribosomal protein L11	0	2	1	3
50S ribosomal protein L7/L12	0	2	1	3
50S ribosomal protein L19	0	2	1	3
50S ribosomal protein L1	0	2	1	3
50S ribosomal protein L20	0	2	1	3
50S ribosomal protein L27	0	2	1	3
50S ribosomal protein L28	0	2	1	3
50S ribosomal protein L29	0	2	1	3
50S ribosomal protein L31	0	2	1	3
50S ribosomal protein L31 type B	0	2	1	3
50S ribosomal protein L32	0	2	1	3
50S ribosomal protein L33	0	2	1	3
50S ribosomal protein L34	0	2	1	3
50S ribosomal protein L35	0	2	1	3
50S ribosomal protein L36	0	2	1	3
30S ribosomal protein S10	0	2	1	3
30S ribosomal protein S11	0	2	1	3
30S ribosomal protein S12	0	2	1	3
30S ribosomal protein S13	0	2	1	3
30S ribosomal protein S16	0	2	1	3
30S ribosomal protein S18	0	2	1	3
30S ribosomal protein S19	0	2	1	3
30S ribosomal protein S20	0	2	1	3
30S ribosomal protein S2	0	2	1	3
30S ribosomal protein S3	0	2	1	3
30S ribosomal protein S4	0	2	1	3
30S ribosomal protein S5	0	2	1	3
30S ribosomal protein S8	0	2	1	3
30S ribosomal protein S9	0	2	1	3
50S ribosomal protein L13	0	2	1	3
50S ribosomal protein L14	0	2	1	3
50S ribosomal protein L16	0	2	1	3
50S ribosomal protein L23	0	2	1	3
30S ribosomal protein S15	0	2	1	3
50S ribosomal protein L17	0	2	1	3
50S ribosomal protein L21	0	2	1	3
50S ribosomal protein L30	0	2	1	3
50S ribosomal protein L6	0	2	1	3
30S ribosomal protein S14	0	2	1	3
30S ribosomal protein S17	0	2	1	3
30S ribosomal protein S1	0	2	1	3
50S ribosomal protein L18	0	2	1	3
60 kDa heat shock protein, mitochondrial	0	1	0	1
Chitinase B	0	1	0	1
Low molecular weight phosphotyrosine protein phosphatase	0	1	0	1
50S ribosomal protein L2	0	2	1	3
50S ribosomal protein L3	0	2	1	3
50S ribosomal protein L24	0	2	1	3
50S ribosomal protein L4	0	2	1	3
50S ribosomal protein L22	0	2	1	3
10 kDa heat shock protein, mitochondrial	0	1	0	1
50S ribosomal protein L5	0	2	1	3
30S ribosomal protein S21	0	2	1	3
50S ribosomal protein L25	0	2	1	3
Cytochrome P450 1B1	0	1	0	1
Thiosulfate sulfurtransferase	0	1	0	1
Lanosterol 14-alpha demethylase	0	2	0	2
50S ribosomal protein L36 2	0	2	1	3
60 kDa chaperonin	0	1	0	1
10 kDa chaperonin	0	1	0	1
NPYLR7B	0	0	2	2
Bloom syndrome protein isoform 1	7	0	0	7
Telomerase reverse transcriptase	0	1	0	1
Coagulation factor XII	0	1	0	1
Amine oxidase [flavin-containing] A	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Delta-type opioid receptor	0	4	0	5
Delta-type opioid receptor	0	6	1	8
Mu-type opioid receptor	0	6	2	11
Kappa-type opioid receptor	0	5	1	7
Kappa-type opioid receptor	0	5	0	5
Mu-type opioid receptor	0	4	1	7
Mu-type opioid receptor	0	5	0	5
Sigma non-opioid intracellular receptor 1	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	1	0	1
glycogen synthase kinase-3 alpha	0	0	0	1
Chain A, Dihydrofolate reductase	0	0	1	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	3	0	0	3
lysosomal alpha-glucosidase preproprotein	2	0	0	2
Thymidylate synthase	0	4	0	4
Thymidylate synthase	0	3	0	3
Dihydrofolate reductase	0	2	3	5
Folylpolyglutamate synthase, mitochondrial	0	1	0	4
Solute carrier organic anion transporter family member 1A3	0	1	0	2
Folylpolyglutamate synthase, mitochondrial	0	1	0	4
Multidrug resistance associated protein	0	1	0	3
Gamma-aminobutyric acid	0	0	1	1
Gamma-aminobutyric acid receptor subunit rho-3	0	0	1	1
Hsf1 protein	0	0	1	1
arylsulfatase A	3	0	0	3
transcriptional regulator ERG isoform 3	2	0	0	2
Histone deacetylase 3	0	1	0	1
Gamma-aminobutyric acid type B receptor subunit 2	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	0	1	1
Gamma-aminobutyric acid receptor subunit delta	0	0	1	1
Gamma-aminobutyric acid receptor subunit rho-1	0	0	2	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit rho-2	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	0	1	1
Histone deacetylase 4	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	0	1	1
Gamma-aminobutyric acid receptor subunit beta-3	0	0	1	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
Histone deacetylase 1	0	1	0	1
Sterol O-acyltransferase 1	0	0	1	1
Proton-coupled amino acid transporter 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	0	1	1
Gamma-aminobutyric acid receptor subunit pi	0	0	1	1
Histone deacetylase 7	0	1	0	1
Histone deacetylase 2	0	1	0	1
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 11	0	1	0	1
Histone deacetylase 8	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	0	1	1
Platelet glycoprotein VI	0	0	1	1
Gamma-aminobutyric acid receptor subunit theta	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	0	1	1
Histone deacetylase 6	0	1	0	1
Gamma-aminobutyric acid type B receptor subunit 1	0	0	1	1
Histone deacetylase 9	0	1	0	1
Histone deacetylase 5	0	1	0	1
Gamma-aminobutyric acid type B receptor subunit 1	0	1	0	1
EWS/FLI fusion protein	9	0	0	9
Beta-1 adrenergic receptor	0	0	1	2
beta-2 adrenergic receptor	3	0	0	3
hexokinase-4 isoform 1	1	0	0	1
glucokinase regulatory protein	1	0	0	1
Beta-2 adrenergic receptor	0	2	4	7
Beta-2 adrenergic receptor	0	2	1	3
Beta-3 adrenergic receptor	0	1	2	3
Beta-1 adrenergic receptor	0	3	1	5
Beta-2 adrenergic receptor	0	0	1	1
Beta-adrenergic receptor kinase 1	0	0	2	2
Beta-3 adrenergic receptor	0	0	1	1
Beta-3 adrenergic receptor	0	1	1	2
Vasopressin V1a receptor	0	1	1	2
Beta-1 adrenergic receptor	0	1	1	2
Alpha-1A adrenergic receptor	0	1	2	3
Alpha-1B adrenergic receptor	0	1	2	3
Beta-2 adrenergic receptor	0	1	0	1
Taste receptor type 2 member 38	0	0	1	1
Taste receptor type 2 member 39	0	0	1	1
Taste receptor type 2 member 40	0	0	1	1
Taste receptor type 2 member 41	0	0	1	1
Taste receptor type 2 member 43	0	0	1	1
Taste receptor type 2 member 31	0	0	1	1
Taste receptor type 2 member 45	0	0	1	1
Taste receptor type 2 member 46	0	0	1	1
Taste receptor type 2 member 30	0	0	1	1
Taste receptor type 2 member 19	0	0	1	1
Taste receptor type 2 member 20	0	0	1	1
Taste receptor type 2 member 50	0	0	1	1
Taste receptor type 2 member 60	0	0	1	1
Oxytocin receptor	0	1	1	2
Beta-2 adrenergic receptor	0	1	2	3
Taste receptor type 2 member 42	0	0	1	1
Beta-2 adrenergic receptor	0	1	2	3
Taste receptor type 2 member 16	0	0	1	1
Taste receptor type 2 member 14	0	0	1	1
Taste receptor type 2 member 13	0	0	1	1
Taste receptor type 2 member 10	0	0	1	1
Taste receptor type 2 member 9	0	0	1	1
Taste receptor type 2 member 8	0	0	1	1
Taste receptor type 2 member 7	0	0	1	1
Taste receptor type 2 member 5	0	0	1	1
Taste receptor type 2 member 4	0	0	1	1
Taste receptor type 2 member 3	0	0	1	1
Taste receptor type 2 member 1	0	0	1	1
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	1	0	0	1
ATP-dependent phosphofructokinase	8	0	0	8
cytochrome P450 2C19 precursor	1	0	0	1
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	3	0	0	3
5-hydroxytryptamine receptor 1D	0	2	0	2
5-hydroxytryptamine receptor 1B	0	2	0	2
5-hydroxytryptamine receptor 5A	0	1	0	1
Synaptic vesicular amine transporter	0	2	0	2
Vesicular acetylcholine transporter	0	1	0	1
Acetylcholinesterase	0	2	0	2
Sodium channel protein type 1 subunit alpha	0	2	0	2
Sodium channel protein type 2 subunit alpha	0	2	0	2
Sodium channel protein type 3 subunit alpha	0	2	0	2
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
GALC protein	2	0	0	2
PINK1	1	0	0	1
Parkin	2	0	0	2
Cytochrome P450 2C19	0	1	0	1
Kappa-type opioid receptor	0	3	1	5
Macrophage migration inhibitory factor	0	2	0	2
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
ClpP	1	0	0	1
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	1	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	1	0	0	1
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	1	0	1
DNA polymerase eta isoform 1	2	0	0	2
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
muscleblind-like protein 1 isoform 1	4	0	0	4
caspase-1 isoform alpha precursor	1	0	0	1
nuclear receptor coactivator 3 isoform a	0	1	0	1
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	3
Thymidylate synthase	0	1	0	1
Tyrosine-protein kinase ABL1	0	0	1	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
High mobility group protein B1	0	0	2	2
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Folate receptor beta	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Histidine decarboxylase	0	1	1	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Cyclin-dependent kinase 2	0	0	1	1
Bifunctional purine biosynthesis protein ATIC	0	2	0	2
Multidrug resistance-associated protein 1	0	0	0	1
Reduced folate transporter	0	2	0	2
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Caspase-7	1	0	0	1
Dihydrofolate reductase	0	1	0	1
Pteridine reductase 1	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Solute carrier organic anion transporter family member 1B3	0	0	0	1
Protein-arginine deiminase type-4	0	1	0	1
Chain A, ATP-DEPENDENT DNA HELICASE Q1	1	0	0	1
DNA polymerase III, partial	1	0	0	1
tumor susceptibility gene 101 protein	1	0	0	1
Thioredoxin reductase	0	1	0	1
Flavodoxin	0	0	0	1
Chain A, PROGESTERONE RECEPTOR	0	1	0	1
Glucocorticoid receptor	0	1	0	1
apical membrane antigen 1, AMA1	1	0	0	1
hypothetical protein, conserved	1	0	0	1
nonstructural protein 1	2	0	0	2
Progesterone receptor	0	4	1	8
Tegument protein VP16	0	0	1	1
Glucocorticoid receptor	0	2	2	5
Glucocorticoid receptor	0	1	1	2
Mineralocorticoid receptor	1	4	2	8
Coagulation factor VII	0	1	0	1
Androgen receptor	1	4	1	6
Cytochrome P450 2C8	0	1	0	1
Thyroid hormone receptor alpha	0	1	0	1
Thyroid hormone receptor beta	0	1	0	1
Steroid 17-alpha-hydroxylase/17,20 lyase	0	1	0	1
Tissue factor	0	1	0	1
Adenosine receptor A1	0	0	1	1
Adenosine receptor A2a	0	0	1	1
Substance-P receptor	0	1	0	1
Progesterone receptor	0	0	1	1
Glucocorticoid receptor	0	1	0	1
Opioid receptor, delta 1b	0	1	0	1
Opioid receptor homologue	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Translocator protein	0	0	1	1
Proteinase-activated receptor 1	0	1	1	2
Nociceptin receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Mas-related G-protein coupled receptor member X2	0	0	1	1
Mu-type opioid receptor	0	1	0	1
Vasopressin V2 receptor	0	1	1	2
Oxytocin receptor	0	2	2	4
Vasopressin V1b receptor	0	1	1	2
Vasopressin V1b receptor	0	1	0	1
Oxytocin receptor	0	0	1	1
Vasopressin V2 receptor	0	1	0	1
Tyrosyl-DNA phosphodiesterase 1	0	1	0	1
Sigma intracellular receptor 2	0	1	0	1
Sigma intracellular receptor 2	0	1	0	1
Estrogen receptor 1	0	1	0	1
fMet-Leu-Phe receptor	0	1	0	1
Nicotinate phosphoribosyltransferase	0	2	0	2
Cyclooxygenase-2	0	1	0	1
Alpha-1B adrenergic receptor	0	0	1	1
POU domain, class 2, transcription factor 1	0	0	0	1
Alpha-1A adrenergic receptor	0	1	1	2
Alpha-1B adrenergic receptor	0	1	0	1
Alpha-2B adrenergic receptor	0	0	0	1
Alpha-2C adrenergic receptor	0	0	0	1
Alpha-2A adrenergic receptor	0	0	0	1
mu-type opioid receptor isoform MOR-1	0	0	1	1
Vpr	1	0	0	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Neuronal acetylcholine receptor subunit alpha-4	1	0	0	1
Neuronal acetylcholine receptor subunit beta-2	1	0	0	1
luciferase	0	0	0	1
Glutamine synthetase	0	0	1	1
Nociceptin receptor	0	0	1	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	2
Voltage-dependent calcium channel subunit alpha-2/delta-2	0	1	0	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Fatty-acid amide hydrolase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	0	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	0	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	0	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
UDP-glucuronosyltransferase 1A8	0	0	0	1
Ubiquitin-like modifier activating enzyme 2	0	1	0	1
SUMO1 activating enzyme subunit 1	0	1	0	1
isocitrate dehydrogenase 1, partial	1	0	0	1
SUMO-conjugating enzyme UBC9	0	1	0	1
eukaryotic translation initiation factor 4 gamma 1 isoform 4	0	1	0	1
eukaryotic translation initiation factor 4E isoform 1	0	1	0	1
hexokinase HKDC1	0	1	0	1
phosphoglycerate kinase	1	0	0	1
Pyridoxal kinase	0	0	0	1
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR	0	0	1	1
Retinol-binding protein 4	0	0	1	1
Beta-lactoglobulin	0	0	1	1
microphthalmia-associated transcription factor isoform 9	0	1	0	1
Insulin-degrading enzyme	0	1	0	1
DNA repair protein RAD52 homolog	0	1	0	1
Integrase	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
Estrogen receptor beta	0	0	0	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	0	1
Solute carrier family 22 member 6	0	1	0	1
Carbonic anhydrase 12	0	1	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Polymerase acidic protein	0	0	1	1
Carbonic anhydrase 3	0	1	0	1
Stromelysin-1	0	0	1	1
Tyrosine-protein phosphatase YopH	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	3
Estrogen receptor	0	0	0	1
Carbonic anhydrase 4	0	1	0	1
Carbonic anhydrase 6	0	1	0	1
Cystathionine gamma-lyase	0	1	0	1
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Carbonic anhydrase 7	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	0	1
Carbonic anhydrase	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
Carbonic anhydrase 15	0	1	0	1
Carbonic anhydrase 13	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	0	1
Carbonic anhydrase 14	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	1	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
Cytochrome P450 14alpha-demethylase	0	0	1	1
Sterol 14-alpha demethylase	0	1	0	1
Carnitine O-palmitoyltransferase 1, muscle isoform	0	1	0	1
Trace amine-associated receptor 1	0	1	0	1
Chain A, PLASMINOGEN	0	0	1	1
Chain A, PLASMINOGEN	0	0	1	1
Plasminogen	0	2	1	3
Urokinase-type plasminogen activator	0	1	0	1
Chain A, CARBONIC ANHYDRASE II	0	1	0	1
Urease subunit alpha	0	1	0	1
Urease subunit beta	0	1	0	1
Olfactory receptor 51E2	0	0	1	1
PPM1D protein	1	0	0	1
Proprotein convertase subtilisin/kexin type 7	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Protease	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

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Studies (437)

Protein Targets (918)

Uterine Rupture

Synonyms(1)

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Overview

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Studies (437)

Drugs Studied (95)

Protein Targets (918)