Unverricht-Lundborg Syndrome

An autosomal recessive condition characterized by recurrent myoclonic and generalized seizures, ATAXIA, slowly progressive intellectual deterioration, DYSARTHRIA, and intention tremor. Myoclonic seizures are severe and continuous, and tend to be triggered by movement, stress, and sensory stimuli. The age of onset is between 8 and 13 years, and the condition is relatively frequent in the Baltic region, especially Finland. (From Menkes, Textbook of Child Neurology, 5th ed, pp109-110)

Synonym
Unverricht-Lundborg Syndrome

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	1 (2.50)	23.3326
1990's	0 (0.00)	12.5806
2000's	18 (45.00)	18.1394
2010's	17 (42.50)	28.8240
2020's	4 (10.00)	9.53

Drug	Relationship Strength	Studies	Trials
gamma-aminobutyric acid	low	2	0
choline	low	2	0
creatine	low	2	0
kynurenine	low	1	0
phenytoin	low	1	0
hydroxyindoleacetic acid	low	1	0
chloral hydrate	low	1	0
clonazepam	medium	2	1
diethyl pyrocarbonate	low	1	0
valproic acid	medium	9	2
lamotrigine	medium	1	1
mephenesin	low	1	0
phenobarbital	medium	1	1
piracetam	medium	7	2
potassium chloride	low	1	0
primidone	low	1	0
propidium	low	1	0
zonisamide	medium	4	1
aspartic acid	low	2	0
tryptophan	low	1	0
dimethyl sulfate	low	1	0
isoxazoles	medium	4	1
thiazoles	low	1	0
kainic acid	low	1	0
acetylcysteine	low	2	0
thioflavin t	low	1	0
glutamic acid	low	1	0
n-acetylaspartic acid	low	1	0
D-fructopyranose	medium	1	1
raclopride	low	1	0
levetiracetam	medium	7	2
topiramate	medium	1	1
perampanel	low	4	0
alpha-synuclein	low	1	0
losartan potassium	low	1	0
guanosine	low	1	0

Protein Targets (493)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, JmjC domain-containing histone demethylation protein 3A	2	0	0	2
Chain A, 2-oxoglutarate Oxygenase	7	0	0	7
Chain A, ATP-DEPENDENT DNA HELICASE Q1	3	0	0	3
acetylcholinesterase	3	0	0	3
dopamine D1 receptor	2	0	0	2
15-lipoxygenase, partial	1	0	0	1
pregnane X receptor	3	0	0	3
phosphopantetheinyl transferase	7	0	0	7
RAR-related orphan receptor gamma	2	0	0	2
USP1 protein, partial	4	0	0	4
NFKB1 protein, partial	2	0	0	2
Microtubule-associated protein tau	5	0	0	5
Thrombopoietin	1	0	0	1
AR protein	6	0	0	6
regulator of G-protein signaling 4	6	0	0	6
glucocorticoid receptor [Homo sapiens]	5	0	0	5
retinoic acid nuclear receptor alpha variant 1	5	0	0	5
retinoid X nuclear receptor alpha	4	0	0	4
farnesoid X nuclear receptor	3	0	0	3
estrogen nuclear receptor alpha	7	0	0	7
vitamin D (1,25- dihydroxyvitamin D3) receptor	3	0	0	3
arylsulfatase A	9	0	0	9
euchromatic histone-lysine N-methyltransferase 2	16	0	0	16
Bloom syndrome protein isoform 1	9	0	0	9
D(1A) dopamine receptor	3	0	0	3
thyroid hormone receptor beta isoform a	5	0	0	5
thyroid hormone receptor beta isoform 2	2	0	0	2
heat shock protein beta-1	1	0	0	1
flap endonuclease 1	6	0	0	6
geminin	11	0	0	11
peripheral myelin protein 22	4	0	0	4
survival motor neuron protein isoform d	1	0	0	1
muscarinic acetylcholine receptor M1	5	0	0	5
Histone deacetylase 3	0	4	0	4
Solute carrier family 22 member 6	0	1	0	1
Histone deacetylase 4	0	4	0	4
Guanine nucleotide-binding protein G	2	0	0	2
Histone deacetylase 1	0	4	0	4
Histone deacetylase 7	0	4	0	4
Histone deacetylase 2	0	4	0	4
Polyamine deacetylase HDAC10	0	4	0	4
Histone deacetylase 11	0	4	0	4
Ataxin-2	2	0	0	2
Histone deacetylase 8	0	4	0	4
Histone deacetylase 6	0	4	0	4
Histone deacetylase 9	0	4	0	4
Histone deacetylase 5	0	4	0	4
ATP-dependent phosphofructokinase	6	0	0	6
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	7	0	0	7
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	3	0	0	3
Chain A, Ferritin light chain	3	0	0	3
aldehyde dehydrogenase 1 family, member A1	4	0	0	4
cytochrome P450 2C19 precursor	4	0	0	4
lethal factor (plasmid)	2	0	0	2
lamin isoform A-delta10	9	0	0	9
Metabotropic glutamate receptor 6	0	1	3	5
Excitatory amino acid transporter 4	0	2	0	2
Glutamate transporter homolog	0	0	1	1
Carbonic anhydrase 1	0	5	0	10
Carbonic anhydrase 2	0	5	2	12
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	1	0	1
5-hydroxytryptamine receptor 1D	0	0	0	1
Glutamate receptor ionotropic, NMDA 1	0	5	2	8
Excitatory amino acid transporter 1	0	3	0	4
Excitatory amino acid transporter 2	0	3	0	4
Excitatory amino acid transporter 3	0	3	0	4
Glutamate receptor ionotropic, NMDA 2A	0	5	2	8
Glutamate receptor ionotropic, NMDA 2B	0	6	2	9
Glutamate receptor ionotropic, NMDA 2C	0	5	2	8
Metabotropic glutamate receptor 1	0	1	2	4
Metabotropic glutamate receptor 2	0	1	2	4
Carbonic anhydrase-like protein, putative	0	0	0	3
Glutamate receptor ionotropic, NMDA 2D	0	5	2	8
Glutamate receptor ionotropic, NMDA 3B	0	5	2	8
Carbonic anhydrase 4	0	2	0	3
Glutamate receptor ionotropic, NMDA 3A	0	5	2	8
peroxisome proliferator-activated receptor delta	1	0	0	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein	0	0	1	1
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Choline-binding protein	0	0	1	1
Solute carrier family 22 member 1	0	1	0	2
Solute carrier family 22 member 2	0	0	0	1
Solute carrier family 22 member 1	0	0	0	1
Solute carrier family 22 member 2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-3	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	0	2	0	2
Neuronal acetylcholine receptor subunit beta-3	0	1	0	1
Neuronal acetylcholine receptor subunit beta-4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-5	0	1	0	1
Acetylcholinesterase	0	3	0	3
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Choline O-acetyltransferase	0	0	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-9	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	2	0	2
Solute carrier family 22 member 1	0	1	0	2
High affinity choline transporter 1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-10	0	1	0	1
Solute carrier family 22 member 2	0	1	0	2
Gamma-aminobutyric acid receptor subunit pi	0	4	0	4
Gamma-aminobutyric acid receptor subunit pi	2	4	0	6
Gamma-aminobutyric acid receptor subunit delta	0	4	0	4
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	4	1	5
Gamma-aminobutyric acid receptor subunit beta-1	2	4	0	6
Gamma-aminobutyric acid receptor subunit beta-1	0	4	1	5
Gamma-aminobutyric acid receptor subunit delta	2	4	0	6
Gamma-aminobutyric acid receptor subunit gamma-2	0	4	1	5
Gamma-aminobutyric acid receptor subunit gamma-2	2	4	1	7
Gamma-aminobutyric acid receptor subunit alpha-5	2	4	0	6
Gamma-aminobutyric acid receptor subunit alpha-3	2	4	0	6
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	2	4	0	6
Gamma-aminobutyric acid receptor subunit alpha-2	2	4	0	6
Gamma-aminobutyric acid receptor subunit alpha-4	2	4	0	6
Gamma-aminobutyric acid receptor subunit beta-3	0	4	1	5
Gamma-aminobutyric acid receptor subunit gamma-3	2	4	0	6
Gamma-aminobutyric acid receptor subunit alpha-6	2	4	0	6
Translocator protein	0	1	0	1
Translocator protein	0	1	0	1
Cholecystokinin receptor type A	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	4	1	5
Gamma-aminobutyric acid receptor subunit alpha-3	0	4	1	5
Gamma-aminobutyric acid receptor subunit alpha-2	0	4	1	5
Gamma-aminobutyric acid receptor subunit beta-2	0	4	1	5
Gamma-aminobutyric acid receptor subunit alpha-4	0	4	1	5
Gamma-aminobutyric acid receptor subunit alpha-1	2	4	1	7
Gamma-aminobutyric acid receptor subunit beta-3	2	4	0	6
Gamma-aminobutyric acid receptor subunit beta-2	2	4	1	7
Gamma-aminobutyric acid receptor subunit epsilon	0	4	0	4
Gamma-aminobutyric acid receptor subunit alpha-6	0	4	1	5
Gamma-aminobutyric acid receptor subunit gamma-1	0	4	0	4
GABA theta subunit	2	4	0	6
Gamma-aminobutyric acid receptor subunit gamma-3	0	4	0	4
Gamma-aminobutyric acid receptor subunit epsilon	2	4	0	6
Gamma-aminobutyric acid receptor subunit theta	0	4	0	4
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Proton-coupled amino acid transporter 1	0	2	0	2
estrogen-related nuclear receptor alpha	6	0	0	6
Sterol O-acyltransferase 2	0	1	0	1
Sterol O-acyltransferase 1	0	1	0	1
Retinal dehydrogenase 1	0	1	0	1
Gamma-aminobutyric acid	0	1	1	2
Gamma-aminobutyric acid receptor subunit rho-3	0	0	1	1
thioredoxin reductase	8	0	0	8
ATAD5 protein, partial	2	0	0	2
Hsf1 protein	0	0	2	3
thyroid stimulating hormone receptor	5	0	0	5
bromodomain adjacent to zinc finger domain 2B	2	0	0	2
transcriptional regulator ERG isoform 3	3	0	0	3
histone-lysine N-methyltransferase 2A isoform 2 precursor	3	0	0	3
histone acetyltransferase KAT2A isoform 1	4	0	0	4
neuropeptide S receptor isoform A	2	0	0	2
Gamma-aminobutyric acid type B receptor subunit 2	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit delta	0	1	1	2
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit rho-1	0	0	2	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit rho-2	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-3	0	1	1	2
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
TAR DNA-binding protein 43	2	0	0	2
Sterol O-acyltransferase 1	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	1	2
Gamma-aminobutyric acid receptor subunit pi	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	1	2
Platelet glycoprotein VI	0	0	1	1
Gamma-aminobutyric acid receptor subunit theta	0	1	1	2
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	1	2
Gamma-aminobutyric acid type B receptor subunit 1	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 1	0	1	0	1
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
glp-1 receptor, partial	1	0	0	1
GLS protein	8	0	0	8
TDP1 protein	5	0	0	5
beta-2 adrenergic receptor	1	0	0	1
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	2	0	0	2
Metabotropic glutamate receptor 8	0	2	0	2
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Glutathione reductase, mitochondrial	0	2	0	2
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
Prothrombin	0	0	1	1
Integrin beta-3	0	0	1	1
Integrin alpha-IIb	0	0	1	1
ATP-citrate synthase	0	1	0	1
Glutamate receptor 1	0	4	2	6
Glutamate receptor 2	0	4	2	6
Glutamate receptor 3	0	4	2	6
Glutamate receptor 4	0	4	2	6
Glutamate receptor ionotropic, kainate 1	0	4	2	6
Metabotropic glutamate receptor 1	0	1	1	2
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 5	0	0	1	1
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Glutamate receptor ionotropic, kainate 1	0	3	2	5
Metabotropic glutamate receptor 5	0	1	2	4
Glutamate receptor ionotropic, kainate 2	0	4	3	7
Glutamate receptor 1	0	4	2	6
Glutamate receptor 2	0	3	2	5
Glutamate receptor 3	0	1	2	3
Glutamate receptor ionotropic, kainate 3	0	4	0	4
Metabotropic glutamate receptor 8	0	0	1	1
Glutamate receptor 4	0	3	1	4
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Fatty-acid amide hydrolase 1	0	1	0	1
Glutamate receptor ionotropic, kainate 4	0	4	0	4
Glutamate carboxypeptidase 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	1	0	1
Glutamate receptor ionotropic, kainate 2	0	3	2	5
Glutamate receptor ionotropic, kainate 3	0	3	0	3
Glutamate receptor ionotropic, NMDA 2B	0	1	0	1
Metabotropic glutamate receptor 7	0	1	1	3
Metabotropic glutamate receptor 3	0	1	1	3
Metabotropic glutamate receptor 4	0	1	1	3
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Glutamate receptor ionotropic, kainate 5	0	3	0	3
Glutamate receptor ionotropic, kainate 5	0	4	0	4
Glutamate racemase	0	0	0	1
Prolyl 4-hydroxylase	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Purine nucleoside phosphorylase	0	0	0	1
Adenosylhomocysteinase	0	1	0	2
endonuclease IV	3	0	0	3
Fumarate hydratase	1	0	0	1
Smad3	2	0	0	2
hypothetical protein, conserved	1	0	0	1
polyprotein	1	0	0	1
alpha-galactosidase	1	0	0	1
IDH1	2	0	0	2
peripheral myelin protein 22 isoform 1	4	0	0	4
cytochrome P450 2C9 precursor	5	0	0	5
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	3	0	0	3
vitamin D3 receptor isoform VDRA	2	0	0	2
chromobox protein homolog 1	7	0	0	7
urokinase-type plasminogen activator precursor	1	0	0	1
plasminogen precursor	1	0	0	1
urokinase plasminogen activator surface receptor precursor	1	0	0	1
M-phase phosphoprotein 8	3	0	0	3
Histamine H2 receptor	5	0	0	5
Uracil nucleotide/cysteinyl leukotriene receptor	0	2	0	2
Chain A, Glutamate receptor 2	0	0	1	1
Chain A, Glutamate receptor 2	0	0	1	1
Chain C, Glutamate receptor 2	0	0	1	1
importin subunit beta-1 isoform 1	1	0	0	1
snurportin-1	1	0	0	1
nuclear receptor ROR-gamma isoform 1	4	0	0	4
DNA polymerase kappa isoform 1	3	0	0	3
Cellular tumor antigen p53	5	0	0	5
Glutamate receptor ionotropic, kainate 4	0	1	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	3	0	0	3
GALC protein	2	0	0	2
EWS/FLI fusion protein	3	0	0	3
cytochrome P450 2D6	4	0	0	4
cytochrome P450 2D6 isoform 1	4	0	0	4
nuclear factor erythroid 2-related factor 2 isoform 2	3	0	0	3
potassium voltage-gated channel subfamily H member 2 isoform d	3	0	0	3
mitogen-activated protein kinase 1	2	0	0	2
Bile salt export pump	0	10	0	10
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	3	0	3
Sodium channel protein type 3 subunit alpha	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Potassium voltage-gated channel subfamily E member 1	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	2	0	4
Potassium voltage-gated channel subfamily KQT member 1	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Sodium channel protein type 5 subunit alpha	0	2	0	2
Sodium channel protein type 9 subunit alpha	0	2	0	2
Sodium channel protein type 2 subunit alpha	0	3	0	3
Sodium channel protein type 3 subunit alpha	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	1	0	1
Sodium channel protein type 10 subunit alpha	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
ATP-binding cassette sub-family C member 3	0	6	0	6
Multidrug resistance-associated protein 4	0	6	0	6
Synaptic vesicle glycoprotein 2A	0	3	0	3
Canalicular multispecific organic anion transporter 1	0	5	0	5
Type-1A angiotensin II receptor	0	1	0	1
Type-1B angiotensin II receptor	0	2	0	2
Type-2 angiotensin II receptor	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	1	0	1
5-hydroxytryptamine receptor 1A	0	1	0	1
Type-1 angiotensin II receptor	0	1	0	1
cytochrome P450 family 3 subfamily A polypeptide 4	2	0	0	2
67.9K protein	1	0	0	1
Solute carrier family 22 member 20	0	1	0	1
Solute carrier family 22 member 6	0	1	0	1
Rap guanine nucleotide exchange factor 4	1	0	0	1
G	2	0	0	2
Interferon beta	3	0	0	3
HLA class I histocompatibility antigen, B alpha chain	2	0	0	2
Replicase polyprotein 1ab	0	1	0	1
Inositol hexakisphosphate kinase 1	2	0	0	2
cytochrome P450 2C9, partial	2	0	0	2
Sodium channel protein type 1 subunit alpha	0	2	0	2
GLI family zinc finger 3	3	0	0	3
nuclear receptor subfamily 1, group I, member 3	3	0	0	3
pregnane X nuclear receptor	3	0	0	3
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	2	0	0	2
atrial natriuretic peptide receptor 1 precursor	1	0	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	1	0	0	1
nuclear factor erythroid 2-related factor 2 isoform 1	2	0	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Cytochrome P450 2C9	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
5-hydroxytryptamine receptor 1A	0	1	0	1
Inositol monophosphatase 1	2	0	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Chain A, Beta-lactamase	1	0	0	1
peroxisome proliferator activated receptor gamma	3	0	0	3
Spike glycoprotein	1	0	0	1
Carbonic anhydrase 4	0	4	0	7
Carbonic anhydrase 5A, mitochondrial	0	4	2	9
Taste receptor type 2 member 31	0	0	1	1
Taste receptor type 2 member 60	0	0	1	1
Carbonic anhydrase 9	0	4	0	7
Sodium/potassium/calcium exchanger 4	0	1	1	2
Taste receptor type 2 member 14	0	0	1	1
Taste receptor type 2 member 13	0	0	1	1
Taste receptor type 2 member 9	0	0	1	1
Taste receptor type 2 member 4	0	0	1	1
Sodium/potassium/calcium exchanger 2	0	1	1	2
thyroid stimulating hormone receptor	2	0	0	2
DNA polymerase beta	1	0	0	1
DNA polymerase iota isoform a (long)	2	0	0	2
Rap guanine nucleotide exchange factor 3	1	0	0	1
runt-related transcription factor 1 isoform AML1b	1	0	0	1
core-binding factor subunit beta isoform 2	1	0	0	1
cytochrome P450 3A4 isoform 1	2	0	0	2
caspase-1 isoform alpha precursor	1	0	0	1
Cholinesterase	0	3	0	3
Acetylcholinesterase	0	1	0	1
Acetylcholinesterase	0	1	0	1
Caspase-7	1	0	0	1
Chain A, HADH2 protein	1	0	0	1
Chain B, HADH2 protein	1	0	0	1
Luciferase	2	0	0	2
D(2) dopamine receptor	0	3	1	4
D(3) dopamine receptor	0	2	0	2
D(4) dopamine receptor	0	1	1	2
D(3) dopamine receptor	0	2	1	3
D(2) dopamine receptor	0	1	0	1
D(2) dopamine receptor	0	5	0	5
5-hydroxytryptamine receptor 1A	0	1	0	1
D(2) dopamine receptor	0	1	0	1
D(1A) dopamine receptor	0	0	1	1
D(1B) dopamine receptor	0	0	1	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Amyloid-beta precursor protein	0	1	0	1
Chain A, Carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase 12	0	3	0	6
Prolyl endopeptidase	0	2	0	2
Carbonic anhydrase-related protein 11	0	0	0	1
Carbonic anhydrase 3	0	3	0	4
Cytochrome P450 3A4	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	2
Cytochrome P450 2C8	0	1	0	1
Arachidonate 5-lipoxygenase-activating protein	0	2	0	2
Carbonic anhydrase 6	0	3	0	6
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Delta-type opioid receptor	0	2	0	2
Cytochrome P450 2C19	0	1	0	1
Delta-type opioid receptor	0	2	0	2
Mu-type opioid receptor	0	2	0	2
Carbonic anhydrase	0	1	0	2
Carbonic anhydrase 7	0	3	0	6
Carbonic anhydrase	0	2	0	3
Carbonic anhydrase	0	2	0	2
Mu-type opioid receptor	0	2	0	2
Beta-carbonic anhydrase 1	0	2	0	2
Carbonic anhydrase 2	0	2	0	2
Carbonic anhydrase, alpha family	0	2	0	2
Carbonic anhydrase	0	2	0	3
Carbonic anhydrase	0	1	0	2
Carbonic anhydrase	0	2	0	3
Carbonic anhydrase	0	2	0	2
Delta carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	2	0	3
Carbonic anhydrase 13	0	3	0	3
Carbonic anhydrase 15	0	2	0	3
Carbonic anhydrase 13	0	1	0	4
Carbonic anhydrase 14	0	3	0	6
Carbonic anhydrase 5B, mitochondrial	0	3	0	6
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
thioredoxin glutathione reductase	1	0	0	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	1	0	0	1
aryl hydrocarbon receptor	1	0	0	1
Dihydrofolate reductase	0	2	0	2
Plasma kallikrein	0	0	0	1
Myeloperoxidase	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Stromelysin-1	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	2
Substance-P receptor	0	1	0	1
Tryptophan 2,3-dioxygenase	0	1	0	2
Large neutral amino acids transporter small subunit 1	0	1	0	1
SLC16A10 protein	0	0	0	1
Tryprostatin B synthase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Monocarboxylate transporter 10	0	0	0	1
Phospholipase A-2-activating protein	0	1	0	1
Cocaine esterase	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	0	0	1
Bile salt export pump	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Cytochrome P450 2A6	0	1	0	1
Tissue factor	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
UDP-glucuronosyltransferase 2B7	0	1	0	2
UDP-glucuronosyltransferase 1-6	0	0	0	1
Liver carboxylesterase 1	0	1	0	1
Nuclear receptor ROR-gamma	1	0	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member B7	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	1	0	1
ATPase family AAA domain-containing protein 5	1	0	0	1
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Translocator protein	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Sodium-dependent dopamine transporter	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Carbonic anhydrase 3	0	1	0	1
Amine oxidase [flavin-containing]	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Unverricht-Lundborg Syndrome

Synonyms(1)

Research

Studies (40)

Protein Targets (493)

Unverricht-Lundborg Syndrome

Synonyms(1)

Research

Studies (40)

Drugs Studied (46)

Protein Targets (493)