| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 1 | 0 | 0 | 1 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | 2 | 0 | 0 | 2 |
| Chain A, Ferritin light chain | 1 | 0 | 0 | 1 |
| interleukin 8 | 1 | 0 | 0 | 1 |
| acetylcholinesterase | 2 | 0 | 0 | 2 |
| thioredoxin reductase | 2 | 0 | 0 | 2 |
| phosphopantetheinyl transferase | 2 | 0 | 0 | 2 |
| RAR-related orphan receptor gamma | 3 | 0 | 0 | 3 |
| SMAD family member 2 | 1 | 0 | 0 | 1 |
| ATAD5 protein, partial | 2 | 0 | 0 | 2 |
| Fumarate hydratase | 2 | 0 | 0 | 2 |
| SMAD family member 3 | 1 | 0 | 0 | 1 |
| TDP1 protein | 5 | 0 | 0 | 5 |
| GLI family zinc finger 3 | 4 | 0 | 0 | 4 |
| Microtubule-associated protein tau | 1 | 0 | 0 | 1 |
| AR protein | 4 | 0 | 0 | 4 |
| thioredoxin glutathione reductase | 2 | 0 | 0 | 2 |
| nuclear receptor subfamily 1, group I, member 3 | 3 | 0 | 0 | 3 |
| EWS/FLI fusion protein | 3 | 0 | 0 | 3 |
| glucocorticoid receptor [Homo sapiens] | 4 | 0 | 0 | 4 |
| retinoic acid nuclear receptor alpha variant 1 | 4 | 0 | 0 | 4 |
| retinoid X nuclear receptor alpha | 2 | 0 | 0 | 2 |
| estrogen-related nuclear receptor alpha | 4 | 0 | 0 | 4 |
| farnesoid X nuclear receptor | 2 | 0 | 0 | 2 |
| pregnane X nuclear receptor | 4 | 0 | 0 | 4 |
| estrogen nuclear receptor alpha | 5 | 0 | 0 | 5 |
| G | 2 | 0 | 0 | 2 |
| polyprotein | 2 | 0 | 0 | 2 |
| P53 | 2 | 0 | 0 | 2 |
| peroxisome proliferator-activated receptor delta | 2 | 0 | 0 | 2 |
| peroxisome proliferator activated receptor gamma | 1 | 0 | 0 | 1 |
| arylsulfatase A | 2 | 0 | 0 | 2 |
| IDH1 | 2 | 0 | 0 | 2 |
| euchromatic histone-lysine N-methyltransferase 2 | 1 | 0 | 0 | 1 |
| aryl hydrocarbon receptor | 3 | 0 | 0 | 3 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 4 | 0 | 0 | 4 |
| thyroid stimulating hormone receptor | 1 | 0 | 0 | 1 |
| activating transcription factor 6 | 2 | 0 | 0 | 2 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | 4 | 0 | 0 | 4 |
| Histone H2A.x | 1 | 0 | 0 | 1 |
| Bloom syndrome protein isoform 1 | 2 | 0 | 0 | 2 |
| peripheral myelin protein 22 isoform 1 | 2 | 0 | 0 | 2 |
| hemoglobin subunit beta | 1 | 0 | 0 | 1 |
| cellular tumor antigen p53 isoform a | 2 | 0 | 0 | 2 |
| thyroid hormone receptor beta isoform 2 | 3 | 0 | 0 | 3 |
| heat shock protein beta-1 | 2 | 0 | 0 | 2 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 3 | 0 | 0 | 3 |
| DNA polymerase iota isoform a (long) | 2 | 0 | 0 | 2 |
| geminin | 3 | 0 | 0 | 3 |
| peripheral myelin protein 22 | 2 | 0 | 0 | 2 |
| survival motor neuron protein isoform d | 2 | 0 | 0 | 2 |
| cytochrome P450 3A4 isoform 1 | 2 | 0 | 0 | 2 |
| M-phase phosphoprotein 8 | 1 | 0 | 0 | 1 |
| muscleblind-like protein 1 isoform 1 | 1 | 0 | 0 | 1 |
| muscarinic acetylcholine receptor M1 | 2 | 0 | 0 | 2 |
| lamin isoform A-delta10 | 3 | 0 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit pi | 2 | 0 | 0 | 2 |
| ATP-binding cassette sub-family C member 3 | 0 | 3 | 0 | 3 |
| Multidrug resistance-associated protein 4 | 0 | 3 | 0 | 3 |
| Bile salt export pump | 0 | 2 | 0 | 2 |
| Voltage-dependent calcium channel gamma-2 subunit | 3 | 0 | 0 | 3 |
| Bile salt export pump | 0 | 4 | 0 | 4 |
| Interferon beta | 3 | 0 | 0 | 3 |
| HLA class I histocompatibility antigen, B alpha chain | 2 | 0 | 0 | 2 |
| Cellular tumor antigen p53 | 4 | 0 | 0 | 4 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit delta | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 2 | 0 | 0 | 2 |
| Glutamate receptor 2 | 3 | 0 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 2 | 0 | 0 | 2 |
| Nuclear receptor ROR-gamma | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 2 | 0 | 0 | 2 |
| GABA theta subunit | 2 | 0 | 0 | 2 |
| Inositol hexakisphosphate kinase 1 | 2 | 0 | 0 | 2 |
| Canalicular multispecific organic anion transporter 1 | 0 | 3 | 0 | 3 |
| ATPase family AAA domain-containing protein 5 | 3 | 0 | 0 | 3 |
| Ataxin-2 | 3 | 0 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit epsilon | 2 | 0 | 0 | 2 |
| Protein-arginine deiminase type-4 | 0 | 2 | 0 | 2 |
| cytochrome P450 2C9, partial | 2 | 0 | 0 | 2 |
| Genome polyprotein | 0 | 1 | 0 | 1 |
| Spike glycoprotein | 0 | 0 | 1 | 1 |
| Replicase polyprotein 1ab | 0 | 0 | 1 | 1 |
| Transmembrane protease serine 2 | 0 | 0 | 1 | 1 |
| Procathepsin L | 0 | 0 | 1 | 1 |
| Muscarinic acetylcholine receptor M2 | 0 | 3 | 0 | 3 |
| Muscarinic acetylcholine receptor M4 | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M5 | 0 | 1 | 0 | 1 |
| Alpha-2A adrenergic receptor | 0 | 1 | 0 | 1 |
| Replicase polyprotein 1a | 0 | 0 | 1 | 1 |
| Replicase polyprotein 1ab | 0 | 0 | 1 | 1 |
| Replicase polyprotein 1ab | 0 | 1 | 1 | 2 |
| Replicase polyprotein 1ab | 0 | 1 | 1 | 2 |
| Muscarinic acetylcholine receptor M1 | 0 | 1 | 0 | 1 |
| Alpha-2B adrenergic receptor | 0 | 1 | 0 | 1 |
| Alpha-2C adrenergic receptor | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M3 | 0 | 2 | 1 | 3 |
| Alpha-1D adrenergic receptor | 0 | 2 | 0 | 2 |
| Spike glycoprotein | 0 | 0 | 1 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | 0 | 1 | 0 | 1 |
| Sigma intracellular receptor 2 | 0 | 1 | 0 | 1 |
| Cyclic GMP-AMP synthase | 0 | 1 | 0 | 1 |
| Sigma non-opioid intracellular receptor 1 | 0 | 1 | 0 | 1 |
| Angiotensin-converting enzyme 2 | 0 | 0 | 1 | 1 |
| Toll-like receptor 9 | 0 | 1 | 0 | 1 |
| Toll-like receptor 7 | 0 | 1 | 0 | 1 |
| Luciferase | 1 | 0 | 0 | 1 |
| glp-1 receptor, partial | 1 | 0 | 0 | 1 |
| matrix metalloproteinase 1, partial | 0 | 0 | 1 | 1 |
| hypoxia-inducible factor 1 alpha subunit | 2 | 0 | 0 | 2 |
| USP1 protein, partial | 1 | 0 | 0 | 1 |
| PPM1D protein | 1 | 0 | 0 | 1 |
| Thrombopoietin | 1 | 0 | 0 | 1 |
| caspase 7, apoptosis-related cysteine protease | 1 | 0 | 0 | 1 |
| progesterone receptor | 3 | 0 | 0 | 3 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 2 | 0 | 0 | 2 |
| nonstructural protein 1 | 1 | 0 | 0 | 1 |
| cytochrome P450 2D6 | 1 | 0 | 0 | 1 |
| Parkin | 1 | 0 | 0 | 1 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | 2 | 0 | 0 | 2 |
| pyruvate kinase | 1 | 0 | 0 | 1 |
| caspase-3 | 1 | 0 | 0 | 1 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | 1 | 0 | 0 | 1 |
| nuclear receptor subfamily 1, group I, member 2 | 2 | 0 | 0 | 2 |
| NPC intracellular cholesterol transporter 1 precursor | 1 | 0 | 0 | 1 |
| cytochrome P450 2C19 precursor | 1 | 0 | 0 | 1 |
| cytochrome P450 2C9 precursor | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform a | 1 | 0 | 0 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | 3 | 0 | 0 | 3 |
| histone deacetylase 9 isoform 3 | 1 | 0 | 0 | 1 |
| huntingtin isoform 2 | 1 | 0 | 0 | 1 |
| ras-related protein Rab-9A | 1 | 0 | 0 | 1 |
| urokinase-type plasminogen activator precursor | 1 | 0 | 0 | 1 |
| plasminogen precursor | 1 | 0 | 0 | 1 |
| urokinase plasminogen activator surface receptor precursor | 1 | 0 | 0 | 1 |
| nuclear receptor ROR-gamma isoform 1 | 2 | 0 | 0 | 2 |
| histone acetyltransferase KAT2A isoform 1 | 1 | 0 | 0 | 1 |
| neuropeptide S receptor isoform A | 1 | 0 | 0 | 1 |
| Dihydroorotate dehydrogenase (quinone), mitochondrial | 0 | 1 | 0 | 1 |
| Integrin beta-3 | 1 | 0 | 0 | 1 |
| Cytochrome P450 1A2 | 0 | 1 | 0 | 1 |
| Aldo-keto reductase family 1 member B1 | 0 | 2 | 0 | 2 |
| Integrin alpha-IIb | 1 | 0 | 0 | 1 |
| Amine oxidase [flavin-containing] A | 0 | 1 | 0 | 1 |
| Endothelin receptor type B | 1 | 0 | 0 | 1 |
| Sodium-dependent noradrenaline transporter | 0 | 2 | 0 | 2 |
| Endothelin-1 receptor | 1 | 0 | 0 | 1 |
| Histamine H2 receptor | 1 | 0 | 0 | 1 |
| Sodium-dependent dopamine transporter | 0 | 2 | 0 | 2 |
| Dihydroorotate dehydrogenase (quinone), mitochondrial | 0 | 1 | 0 | 1 |
| Dihydroorotate dehydrogenase (quinone), mitochondrial | 0 | 1 | 0 | 1 |
| luciferase | 0 | 0 | 0 | 1 |
| Fatty acid-binding protein, liver | 0 | 1 | 0 | 1 |
| Estrogen receptor | 0 | 2 | 0 | 2 |
| Glucocorticoid receptor | 0 | 4 | 3 | 12 |
| Progesterone receptor | 0 | 2 | 0 | 3 |
| Glucocorticoid receptor | 0 | 1 | 1 | 2 |
| Glucocorticoid receptor | 0 | 0 | 1 | 1 |
| Glycine receptor subunit alpha-1 | 0 | 4 | 0 | 4 |
| Corticosteroid-binding globulin | 0 | 1 | 0 | 1 |
| Mineralocorticoid receptor | 0 | 2 | 1 | 3 |
| Androgen receptor | 0 | 2 | 0 | 2 |
| Cytochrome P450 2C9 | 0 | 1 | 0 | 1 |
| Glutamine synthetase | 0 | 0 | 1 | 1 |
| Androgen receptor | 0 | 1 | 0 | 1 |
| Glycine receptor subunit beta | 0 | 4 | 0 | 4 |
| Glycine receptor subunit alpha-2 | 0 | 4 | 0 | 4 |
| Glycine receptor subunit alpha-3 | 0 | 4 | 0 | 4 |
| Histamine H1 receptor | 0 | 0 | 1 | 1 |
| Prostaglandin G/H synthase 2 | 0 | 1 | 0 | 1 |
| Nociceptin receptor | 0 | 0 | 1 | 1 |
| Cytochrome P450 2J2 | 0 | 1 | 0 | 1 |
| Estrogen receptor beta | 0 | 2 | 0 | 2 |
| Chain A, HADH2 protein | 1 | 0 | 0 | 1 |
| Chain B, HADH2 protein | 1 | 0 | 0 | 1 |
| pregnane X receptor | 1 | 0 | 0 | 1 |
| aldehyde dehydrogenase 1 family, member A1 | 1 | 0 | 0 | 1 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 1 | 0 | 0 | 1 |
| estrogen receptor 2 (ER beta) | 1 | 0 | 0 | 1 |
| vitamin D3 receptor isoform VDRA | 1 | 0 | 0 | 1 |
| Chain A, Beta-lactamase | 1 | 0 | 0 | 1 |
| chromobox protein homolog 1 | 1 | 0 | 0 | 1 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | 1 | 0 | 0 | 1 |
| Ubiquitin carboxyl-terminal hydrolase 2 | 0 | 1 | 0 | 1 |
| Vitamin D3 receptor | 0 | 1 | 1 | 2 |
| Alpha-synuclein | 1 | 0 | 0 | 1 |
| Guanine nucleotide-binding protein G | 1 | 0 | 0 | 1 |
| Ileal sodium/bile acid cotransporter | 0 | 1 | 0 | 1 |
| TAR DNA-binding protein 43 | 1 | 0 | 0 | 1 |
| Sodium/bile acid cotransporter | 0 | 1 | 0 | 1 |
| G-protein coupled bile acid receptor 1 | 0 | 0 | 1 | 1 |
| Bile acid receptor | 0 | 0 | 1 | 1 |
| CDGSH iron-sulfur domain-containing protein 1 | 0 | 2 | 0 | 2 |
| M1-family alanyl aminopeptidase | 0 | 1 | 0 | 1 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |