Page last updated: 2024-09-27

Anodontia

Congenital absence of the teeth; it may involve all (total anodontia) or only some of the teeth (partial anodontia, hypodontia), and both the deciduous and the permanent dentition, or only teeth of the permanent dentition. (Dorland, 27th ed)

Synonyms(5)

Synonym
Anodontia
Tooth Agenesis, Familial
Tooth Agenesis, Selective, 1
Hypodontia Oligodontia 1
Hypodontia

Research Excerpts

Overview

ExcerptReference
"Hypodontia is associated with lack of development of the alveolar ridge and results in less volume of bone for support of conventional prostheses."( Brahim, JS; Guckes, AD; King, TS; McCarthy, GR; Scurria, MS, 2002)
"Hypodontia is often found during orthodontic screening and occurs with a prevalence of between 5% and 10%."( Blatz, MB; Geiselhoringer, H; Holst, AI; Holst, S; Nkenke, E, 2008)
"Pseudoanodontia is a rare clinical and radiologic manifestation that is always associated with GAPO syndrome."( Hallur, N; Puranik, RS; Puranik, SR; Venkatesh, D, 2018)

Context

ExcerptReference
"It thus seems that hypodontia has little effect on the general growth pattern, and that orthodontic treatment in hypodontia patients should follow the same guidelines in relation to growth as in any other children."( Bøe, OE; Roald, KL; Wisth, PJ, 1982)
"Hypodontia has a significant impact on oral health related quality of life."( Anweigi, L; Finbarr Allen, P; Ziada, H, 2013)

Treatment

ExcerptReference
"Although congenital partial hypodontia is widespread, and a variety of solutions for treating this condition in adolescents have been devised, all have had one or more significant drawbacks."( Drake, B; Holt, LR, 2008)

Research

Studies (239)

TimeframeStudies, This Condition (%)All Conditions %
pre-199052 (21.76)23.3326
1990's29 (12.13)12.5806
2000's60 (25.10)18.1394
2010's89 (37.24)28.8240
2020's9 (3.77)9.53
DrugIndicatedRelationship StrengthStudiesTrials
adenine0low70
choline0low10
citric acid, anhydrous0low10
chlorine0low10
salicylic acid0low10
cytosine0low100
glycine0low40
iodine0low20
inositol0low10
nickel0low40
phosphoric acid0low10
thymine0low100
urea0low10
phenytoin0low10
caffeine0low10
lidocaine0low10
isoflurane0low10
2-propanol0low130
metformin0low10
procainamide0low10
propranolol0low10
thalidomide0low20
thymidine0low10
androsterone0low10
pilocarpine0low20
alanine0low20
serine0low30
glutamine0low30
tyrosine0low10
leucine0low60
phenylalanine0low30
histidine0low10
valine0low20
threonine0low10
tryptophan0low30
isoleucine0low20
arginine0low50
tetraethyleneglycol dimethacrylate0low10
durapatite0low10
s,n,n'-tripropylthiocarbamate0low10
mercury0low10
titanium0medium131
chromium0low10
yttrium0low10
zirconium0medium101
calcium sulfate0low10
zinc phosphate0low10
cephalexin0low10
fluorides0low10
carbamide peroxide0low10
tridemorph0low10
glutamic acid0low10
vecuronium bromide0low10
propiconazole0low50
trazodone hydrochloride0low10
cobalt0low20
2'-5'-oligoadenylate trimer0low10
methotrexate0low10
proline0low30
elastin0low10
inositol 3-phosphate0low440
retinol0low10
cocaine0low10
lycopene0low10
bromochloroacetic acid0low10
u 01260low10
beta carotene0low10
lutein0low10
phenylephrine hydrochloride0low220
acitretin0low10
cysteine0low30
aluminum oxide0low40
jaw0low110
vendex0low40
silicate cement0low30
sodium ethylxanthate0low40
heliosit0low10
ascorbic acid0low10
epidermal growth factor0low10
transforming growth factor beta0low70
feldspar0low50
transforming growth factor alpha0low50
exudates0low40
levoleucovorin0low10
guanine0low110

Protein Targets (884)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
hypoxia-inducible factor 1 alpha subunit3003
RAR-related orphan receptor gamma160016
GLI family zinc finger 3190019
AR protein240024
aldehyde dehydrogenase 1 family, member A1170017
retinoic acid nuclear receptor alpha variant 1160016
retinoid X nuclear receptor alpha130013
estrogen nuclear receptor alpha290029
peroxisome proliferator-activated receptor delta6006
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a110011
activating transcription factor 64004
v-jun sarcoma virus 17 oncogene homolog (avian)6006
Histone H2A.x6006
thyroid hormone receptor beta isoform a9009
heat shock protein beta-14004
nuclear factor erythroid 2-related factor 2 isoform 1180018
lamin isoform A-delta10160016
Voltage-dependent calcium channel gamma-2 subunit7007
Glutamate receptor 272110
Chain A, JmjC domain-containing histone demethylation protein 3A2002
Luciferase4004
USP1 protein, partial4004
TDP1 protein200020
Microtubule-associated protein tau8008
glucocorticoid receptor [Homo sapiens]160016
peroxisome proliferator activated receptor gamma120012
euchromatic histone-lysine N-methyltransferase 2200020
vitamin D3 receptor isoform VDRA8008
thyroid hormone receptor beta isoform 2110011
flap endonuclease 19009
serine/threonine-protein kinase PLK11001
eyes absent homolog 2 isoform a1001
DNA polymerase eta isoform 12002
geminin160016
peripheral myelin protein 227007
survival motor neuron protein isoform d4004
histone acetyltransferase KAT2A isoform 18008
ATP-binding cassette sub-family C member 3010010
Multidrug resistance-associated protein 4010011
Bile salt export pump0404
Bile salt export pump014014
Rap guanine nucleotide exchange factor 32002
Cellular tumor antigen p539009
Rap guanine nucleotide exchange factor 41001
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE8008
Chain A, MTA/SAH nucleosidase0101
Chain A, Ribosome-inactivating protein alpha-trichosanthin0011
Chain A, Ricin A chain0011
Chain A, Ribosome-inactivating protein 30011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
nuclear receptor subfamily 1, group I, member 3120012
cytochrome P450 family 3 subfamily A polypeptide 45005
estrogen-related nuclear receptor alpha180018
pregnane X nuclear receptor100010
nuclear factor erythroid 2-related factor 2 isoform 23003
importin subunit beta-1 isoform 12002
snurportin-12002
tumor susceptibility gene 101 protein1001
GTP-binding nuclear protein Ran isoform 11001
Cyclin-dependent kinase 10101
Heat shock protein HSP 90-beta0101
Xanthine dehydrogenase/oxidase0101
TAR DNA-binding protein 435005
Protein mono-ADP-ribosyltransferase PARP150101
Leucine-rich repeat serine/threonine-protein kinase 20202
ATPase family AAA domain-containing protein 53003
Ataxin-24004
Chain A, TYROSYL-DNA PHOSPHODIESTERASE5005
Carbonic anhydrase 105013
Carbonic anhydrase 205114
Alanine racemase, biosynthetic0001
5-hydroxytryptamine receptor 1D0002
Glutamate receptor ionotropic, NMDA 1 07213
Proton-coupled amino acid transporter 10607
Adenosine deaminase0001
Carbonic anhydrase 40002
Chain A, retinol dehydratase0101
acetylcholinesterase6006
estrogen receptor 2 (ER beta)5005
progesterone receptor6006
Gamma-aminobutyric acid receptor subunit pi4318
Sex hormone-binding globulin0011
Corticosteroid-binding globulin0101
Glucose-6-phosphate 1-dehydrogenase0303
Androgen receptor0101
Gamma-aminobutyric acid receptor subunit beta-14318
Gamma-aminobutyric acid receptor subunit delta4318
Gamma-aminobutyric acid receptor subunit gamma-24318
Gamma-aminobutyric acid receptor subunit alpha-54318
Gamma-aminobutyric acid receptor subunit alpha-34318
Gamma-aminobutyric acid receptor subunit gamma-14318
Gamma-aminobutyric acid receptor subunit alpha-24318
Gamma-aminobutyric acid receptor subunit alpha-44318
Gamma-aminobutyric acid receptor subunit gamma-34318
Gamma-aminobutyric acid receptor subunit alpha-64318
Solute carrier organic anion transporter family member 1A10101
Gamma-aminobutyric acid receptor subunit alpha-14318
Gamma-aminobutyric acid receptor subunit beta-34318
Gamma-aminobutyric acid receptor subunit beta-24318
G-protein coupled bile acid receptor 10011
GABA theta subunit4318
Gamma-aminobutyric acid receptor subunit epsilon4318
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0022
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0022
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0022
thioredoxin reductase130013
phosphopantetheinyl transferase120012
NFKB1 protein, partial1001
GLS protein8008
thyroid stimulating hormone receptor5005
alpha-galactosidase2002
cytochrome P450 2C19 precursor3003
chromobox protein homolog 1110011
DNA polymerase iota isoform a (long)7007
muscarinic acetylcholine receptor M17007
lethal factor (plasmid)6006
Cytochrome P450 3A40203
Nitric oxide synthase, endothelial0002
Nitric oxide synthase, brain0001
Nitric oxide synthase, brain 0001
Nitric oxide synthase, inducible0001
Nitric oxide synthase, inducible0013
Cationic amino acid transporter 30101
ATP-dependent phosphofructokinase8008
Chain A, Hyaluronidase, phage associated0101
thioredoxin glutathione reductase2002
vitamin D (1,25- dihydroxyvitamin D3) receptor6006
IDH15005
lethal(3)malignant brain tumor-like protein 1 isoform I1001
Polyphenol oxidase 20204
Pancreatic alpha-amylase0202
Albumin0101
Urease0101
Prolyl 4-hydroxylase subunit alpha-10001
Tyrosinase0101
Alpha-2B adrenergic receptor0023
Spike glycoprotein4004
Hyaluronate lyase0101
Prolyl hydroxylase EGLN20001
Egl nine homolog 10001
Prolyl hydroxylase EGLN30001
Hypoxia-inducible factor 1-alpha inhibitor0001
Solute carrier family 23 member 10101
core protein, partial0101
Solute carrier organic anion transporter family member 1B30203
Solute carrier organic anion transporter family member 1B10202
thyroid stimulating hormone receptor5005
Nuclear receptor ROR-gamma2002
Chain A, Glycogen Phosphorylase0101
Chain A, Glycogen phosphorylase, liver form0011
Chain A, glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Chitinase0101
farnesoid X nuclear receptor6006
atrial natriuretic peptide receptor 1 precursor2002
DNA polymerase beta2002
nuclear receptor ROR-gamma isoform 14004
DNA polymerase kappa isoform 15005
Potassium channel subfamily K member 20112
Glycogen phosphorylase, muscle form0101
Renin0101
Cholinesterase0101
Glycogen phosphorylase, liver form0101
Glycogen phosphorylase, muscle form0101
Replicase polyprotein 1ab0101
Adenosine receptor A30213
Replicase polyprotein 1ab0101
Amine oxidase [flavin-containing] A0101
Acetylcholinesterase0505
Adenosine receptor A10206
Amine oxidase [flavin-containing] B0202
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0303
Adenosine receptor A30101
Adenosine receptor A2a0326
Adenosine receptor A2b0102
Adenosine receptor A2b0203
Adenosine receptor A10114
Adenosine receptor A2a0207
Vasopressin V2 receptor0001
Serine/threonine-protein kinase mTOR0101
Adenosine receptor A2a0101
Adenosine receptor A10101
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0101
DNA-dependent protein kinase catalytic subunit0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Adenylate cyclase type 10001
Chitotriosidase-10101
Serine-protein kinase ATM0101
Serine/threonine-protein kinase ATR0101
Adenosine receptor A2b0102
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
Palmitoleoyl-protein carboxylesterase NOTUM0123
Endochitinase B10101
Muscarinic acetylcholine receptor0001
Canalicular multispecific organic anion transporter 10808
Phosphodiesterase 0101
Broad substrate specificity ATP-binding cassette transporter ABCG20102
Guanine deaminase0102
Chain A, Putative fructose-1,6-bisphosphate aldolase2002
bromodomain adjacent to zinc finger domain 2B2002
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 14004
mitogen-activated protein kinase 14004
Solute carrier family 22 member 60303
Interferon beta2002
Solute carrier family 15 member 10202
Solute carrier family 15 member 10101
B2 metallo-beta-lactamase 0001
Solute carrier family 15 member 20101
Solute carrier family 15 member 20102
Solute carrier family 22 member 80101
Carbonic anhydrase 40307
Carbonic anhydrase0206
Carbonic anhydrase 150307
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein0011
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Choline-binding protein0011
Solute carrier family 22 member 10203
Solute carrier family 22 member 20304
Solute carrier family 22 member 1 0305
Solute carrier family 22 member 20202
Neuronal acetylcholine receptor subunit alpha-30101
Neuronal acetylcholine receptor subunit alpha-41102
Neuronal acetylcholine receptor subunit alpha-20101
Neuronal acetylcholine receptor subunit beta-21102
Neuronal acetylcholine receptor subunit beta-30101
Neuronal acetylcholine receptor subunit beta-40101
Neuronal acetylcholine receptor subunit alpha-50101
Sodium- and chloride-dependent creatine transporter 10101
Choline O-acetyltransferase 0001
Neuronal acetylcholine receptor subunit alpha-60101
Neuronal acetylcholine receptor subunit alpha-90101
Neuronal acetylcholine receptor subunit alpha-70101
Solute carrier family 22 member 10305
High affinity choline transporter 10101
Neuronal acetylcholine receptor subunit alpha-100101
Solute carrier family 22 member 20304
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase0011
hepatocyte nuclear factor 4-alpha isoform 20101
perilipin-50101
perilipin-10101
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a0101
Beta-lactamase0101
Proto-oncogene tyrosine-protein kinase Src0202
3-dehydroquinate dehydratase0011
ATP-citrate synthase 0102
Ribonuclease T0001
Cell death-related nuclease 40001
3-dehydroquinate dehydratase0011
Prolyl 4-hydroxylase0202
Alpha-ketoglutarate-dependent dioxygenase FTO0202
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain H, Fab M82G2, Heavy chain0011
Chain L, Fab M82G2, Light chain0011
Chain H, Fab M82g2, Heavy Chain0011
Chain L, Fab M82g2, Light Chain0011
Gamma-aminobutyric acid receptor subunit pi0202
Gamma-aminobutyric acid receptor subunit delta0202
Amyloid-beta precursor protein0303
Fatty acid-binding protein, heart0101
Muscarinic acetylcholine receptor M20101
Muscarinic acetylcholine receptor M10304
5-hydroxytryptamine receptor 2C0304
Tryptophan 5-hydroxylase 10101
5-hydroxytryptamine receptor 2A0303
Gamma-aminobutyric acid receptor subunit alpha-10202
Gamma-aminobutyric acid receptor subunit beta-10202
Gamma-aminobutyric acid receptor subunit gamma-20202
D0101
5-hydroxytryptamine receptor 1A0416
Alpha-2B adrenergic receptor0112
Alpha-2C adrenergic receptor0112
Alpha-2A adrenergic receptor0112
Liver carboxylesterase 10001
Sodium-dependent noradrenaline transporter 0202
Sodium-dependent dopamine transporter0202
Gamma-aminobutyric acid receptor subunit beta-30202
5-hydroxytryptamine receptor 1B0303
5-hydroxytryptamine receptor 1D0101
5-hydroxytryptamine receptor 1F0101
5-hydroxytryptamine receptor 2B0202
5-hydroxytryptamine receptor 60101
Gamma-aminobutyric acid receptor subunit alpha-50202
Sodium-dependent serotonin transporter0404
Sodium-dependent serotonin transporter0203
5-hydroxytryptamine receptor 7 0101
Gamma-aminobutyric acid receptor subunit alpha-30202
5-hydroxytryptamine receptor 5A0101
5-hydroxytryptamine receptor 5B0101
5-hydroxytryptamine receptor 3A0101
Lysosomal Pro-X carboxypeptidase0101
Gamma-aminobutyric acid receptor subunit alpha-20202
Gamma-aminobutyric acid receptor subunit beta-20202
Gamma-aminobutyric acid receptor subunit alpha-40202
D(2) dopamine receptor0101
Gamma-aminobutyric acid receptor subunit epsilon0202
Glutamate receptor ionotropic, NMDA 2A 05211
Glutamate receptor ionotropic, NMDA 2B05211
Glutamate receptor ionotropic, NMDA 2C05211
Sodium-dependent dopamine transporter 0202
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0202
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0202
Potassium voltage-gated channel subfamily H member 20505
Leukotriene B4 receptor 10101
Gamma-aminobutyric acid receptor subunit alpha-60202
Sodium-dependent dopamine transporter0202
Glutamate receptor ionotropic, NMDA 2D05211
5-hydroxytryptamine receptor 4 0101
Gamma-aminobutyric acid receptor subunit gamma-10202
Glutamate receptor ionotropic, NMDA 3B05211
Sigma non-opioid intracellular receptor 10404
Gamma-aminobutyric acid receptor subunit gamma-30202
5-hydroxytryptamine receptor 3B0101
Leukotriene B4 receptor 20101
Glutamate receptor ionotropic, NMDA 3A05211
Gamma-aminobutyric acid receptor subunit theta0202
Transporter0202
Deoxycytidine kinase0001
Chain A, GLUTAMATE RECEPTOR SUBUNIT 20101
Chain A, Glutamate Receptor Subunit 20101
Chain B, Glutamate Receptor Subunit 20101
Chain A, Slr1257 protein0011
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]0101
glp-1 receptor, partial3003
regulator of G-protein signaling 44004
beta-2 adrenergic receptor2002
peptidyl-prolyl cis-trans isomerase NIMA-interacting 14004
Metabotropic glutamate receptor 80202
Metabotropic glutamate receptor 60113
Glutamate receptor ionotropic, NMDA 2D0101
Excitatory amino acid transporter 40101
Glutamate receptor ionotropic, NMDA 3B0101
Glutathione reductase, mitochondrial0202
Bifunctional aspartokinase/homoserine dehydrogenase 10101
Prothrombin0011
Integrin beta-32013
Integrin alpha-IIb2013
Glutamate receptor 10213
Glutamate receptor 30213
Glutamate receptor 40213
Glutamate receptor ionotropic, kainate 10213
Metabotropic glutamate receptor 10112
Metabotropic glutamate receptor 20011
Metabotropic glutamate receptor 30011
Metabotropic glutamate receptor 40112
Metabotropic glutamate receptor 50011
Metabotropic glutamate receptor 60011
Metabotropic glutamate receptor 70011
Glutamate receptor ionotropic, kainate 10112
Metabotropic glutamate receptor 50113
Glutamate receptor ionotropic, kainate 20213
Glutamate receptor 10213
Glutamate receptor 20213
Glutamate receptor 30112
Glutamate receptor ionotropic, kainate 30202
Excitatory amino acid transporter 10203
Excitatory amino acid transporter 20203
Excitatory amino acid transporter 30203
Metabotropic glutamate receptor 80011
Glutamate receptor 40213
Excitatory amino acid transporter 3 0001
Glutamate racemase0001
Metabotropic glutamate receptor 80112
Fatty-acid amide hydrolase 10101
Glutamate receptor ionotropic, kainate 40202
Glutamate carboxypeptidase 20101
Glutamate receptor ionotropic, NMDA 10101
Glutamate receptor ionotropic, NMDA 2A0101
Glutamate receptor ionotropic, kainate 20112
Glutamate receptor ionotropic, kainate 30101
Glutamate receptor ionotropic, NMDA 2B0101
Metabotropic glutamate receptor 10113
Metabotropic glutamate receptor 20113
Metabotropic glutamate receptor 70113
Metabotropic glutamate receptor 30113
Metabotropic glutamate receptor 40113
Glutamate receptor ionotropic, NMDA 2C0101
Glutamate receptor ionotropic, kainate 50101
Carbonic anhydrase-like protein, putative0006
Glutamate receptor ionotropic, kainate 50202
Glutamate racemase0001
Glutamate receptor ionotropic, NMDA 3A0101
Chain A, Glutamine Binding Protein0011
15-lipoxygenase, partial3003
arylsulfatase A6006
Bloom syndrome protein isoform 16006
peripheral myelin protein 22 isoform 13003
histone-lysine N-methyltransferase 2A isoform 2 precursor2002
Neutral amino acid transporter A0303
Asc-type amino acid transporter 10101
Neutral amino acid transporter B(0)0303
Amino acid transporter0303
Glycine receptor subunit alpha-10011
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent glycine transporter 10101
Large neutral amino acids transporter small subunit 10809
Serine racemase0101
Olfactory receptor 51E20022
Sodium- and chloride-dependent glycine transporter 20101
Purine nucleoside phosphorylase0202
Hypoxanthine-guanine phosphoribosyltransferase0001
Ricin0101
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase0011
Purine nucleoside phosphorylase 0012
Shiga toxin subunit A0101
Chain A, HISTIDINE-BINDING PROTEIN0011
ATAD5 protein, partial3003
cytochrome P450 3A4 isoform 14004
Carbonic anhydrase 120105
Plasma kallikrein0004
Carbonic anhydrase 30105
Histidine-binding periplasmic protein0011
Carbonic anhydrase 60105
Carbonic anhydrase 5A, mitochondrial0105
Carbonic anhydrase 70105
Carbonic anhydrase0004
Glutaminyl-peptide cyclotransferase0101
Carbonic anhydrase 90105
Carbonic anhydrase 0004
Carbonic anhydrase0004
Carbonic anhydrase0004
Carbonic anhydrase 0004
Carbonic anhydrase 130002
Carbonic anhydrase 130104
Carbonic anhydrase 140105
Carbonic anhydrase 5B, mitochondrial0105
Chain B, Pulmonary surfactant-associated protein D0101
Chain A, Pulmonary surfactant-associated protein D0101
parathyroid hormone/parathyroid hormone-related peptide receptor precursor3003
Sodium/myo-inositol cotransporter 20101
aryl hydrocarbon receptor4004
histone deacetylase 9 isoform 31001
Neuronal acetylcholine receptor subunit beta-20101
Neuronal acetylcholine receptor subunit alpha-70101
interleukin 82002
cellular tumor antigen p53 isoform a2002
Chymotrypsinogen A0101
Chain A, AMINOPEPTIDASE0202
Chain A, AMINOPEPTIDASE0202
Chain A, Leucine Aminopeptidase0101
Alkaline phosphatase, tissue-nonspecific isozyme0303
Intestinal-type alkaline phosphatase0303
Phospholipase A-2-activating protein0303
Chain A, Beta-lactamase2002
Potassium channel subfamily K member 30101
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0202
Sodium channel protein type 3 subunit alpha0101
Potassium voltage-gated channel subfamily A member 50101
Sodium channel protein type 4 subunit alpha0203
Sodium channel protein type 5 subunit alpha0303
Sodium channel protein type 9 subunit alpha0202
Potassium voltage-gated channel subfamily D member 20101
Potassium channel subfamily K member 180101
Multidrug and toxin extrusion protein 10303
Sodium channel protein type 3 subunit alpha0202
retinoic acid receptor alpha isoform 10101
retinoic acid receptor RXR-alpha isoform a0101
potassium voltage-gated channel subfamily H member 2 isoform d3003
Chain A, Ferritin light chain5005
EWS/FLI fusion protein4004
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a1001
Dihydrofolate reductase0506
Dipeptidyl peptidase 40101
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain A, HADH2 protein2002
Chain B, HADH2 protein2002
Chain A, 2-oxoglutarate Oxygenase6006
acid sphingomyelinase2002
dopamine D1 receptor1001
ClpP1001
67.9K protein2002
Thymidylate synthase 0101
Thymidylate synthase 0101
polyunsaturated fatty acid lipoxygenase ALOX121001
transcriptional regulator ERG isoform 32002
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0101
transactivating tegument protein VP16 [Human herpesvirus 1]0101
M-phase phosphoprotein 82002
muscleblind-like protein 1 isoform 11001
caspase-1 isoform alpha precursor1001
nuclear receptor coactivator 3 isoform a0101
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0203
Dihydrofolate reductase 0202
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Tyrosine-protein kinase ABL10011
Thymidylate synthase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Thymidylate synthase0203
High mobility group protein B10022
Dihydrofolate reductase0101
Thymidylate synthase0101
Dihydrofolate reductase0224
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0101
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Dihydrofolate reductase0202
Histidine decarboxylase0101
Trifunctional purine biosynthetic protein adenosine-30101
Cyclin-dependent kinase 20011
Bifunctional purine biosynthesis protein ATIC0202
Multidrug resistance-associated protein 1 0001
Delta-type opioid receptor0101
Mu-type opioid receptor0101
Kappa-type opioid receptor0101
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
6-phosphogluconate dehydrogenase, decarboxylating0101
Caspase-71001
Solute carrier organic anion transporter family member 1A30001
Dihydrofolate reductase0101
Pteridine reductase 10101
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Solute carrier family 22 member 60102
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Solute carrier family 22 member 200202
Dihydrofolate reductase 0101
Solute carrier family 22 member 80103
Solute carrier family 22 member 60202
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Multidrug resistance associated protein0102
Solute carrier family 22 member 110002
Protein-arginine deiminase type-40202
Voltage-dependent calcium channel subunit alpha-2/delta-10101
Alkaline phosphatase, tissue-nonspecific isozyme 0101
Intestinal-type alkaline phosphatase0101
5'-nucleotidase0101
E3 ubiquitin-protein ligase XIAP0101
SLC16A10 protein0003
Large neutral amino acids transporter small subunit 1 0101
Monocarboxylate transporter 100003
GALC protein1001
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)2002
lysosomal alpha-glucosidase preproprotein1001
mu-type opioid receptor isoform MOR-10011
Vpr1001
5-hydroxytryptamine receptor 2A0011
Gamma-aminobutyric acid 0101
endonuclease IV1001
G1001
cytochrome P450 2C9 precursor2002
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Voltage-dependent L-type calcium channel subunit alpha-1F0202
HLA class I histocompatibility antigen, B alpha chain 1001
Cytochrome P450 2C9 0202
Aldo-keto reductase family 1 member B10101
Gamma-aminobutyric acid receptor subunit alpha-60101
Gamma-aminobutyric acid receptor subunit gamma-20101
Gamma-aminobutyric acid receptor subunit delta0101
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit alpha-30101
Gamma-aminobutyric acid receptor subunit gamma-30101
Sodium channel protein type 1 subunit alpha0101
Histamine H2 receptor3003
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit alpha-10101
Gamma-aminobutyric acid receptor subunit beta-30101
Inositol monophosphatase 12002
Voltage-dependent L-type calcium channel subunit alpha-1D 0202
Voltage-dependent L-type calcium channel subunit alpha-1S0202
Voltage-dependent L-type calcium channel subunit alpha-1C0303
Gamma-aminobutyric acid receptor subunit alpha-50101
Gamma-aminobutyric acid receptor subunit pi0101
Inositol hexakisphosphate kinase 11001
Sodium channel protein type 2 subunit alpha0101
Gamma-aminobutyric acid receptor subunit alpha-40101
Gamma-aminobutyric acid receptor subunit theta0101
Gamma-aminobutyric acid receptor subunit gamma-10101
cytochrome P450 2C9, partial1001
SMAD family member 23003
SMAD family member 33003
Ornithine transcarbamylase, mitochondrial0101
2-dehydropantoate 2-reductase0101
Nociceptin receptor0101
Fe(3+)-Zn(2+) purple acid phosphatase0101
Muscarinic acetylcholine receptor M20325
Muscarinic acetylcholine receptor M30203
Muscarinic acetylcholine receptor M40203
Muscarinic acetylcholine receptor M50203
Muscarinic acetylcholine receptor M50101
Muscarinic acetylcholine receptor M20203
Muscarinic acetylcholine receptor M10235
Cytochrome P450 2A60112
Muscarinic acetylcholine receptor M10011
Muscarinic acetylcholine receptor DM10101
Cytochrome P450 2A130112
Sterol O-acyltransferase 10101
Solute carrier family 22 member 30101
Acetylcholinesterase 0101
DNA (cytosine-5)-methyltransferase 10101
Sterol O-acyltransferase 10101
Solute carrier family 22 member 40101
DNA (cytosine-5)-methyltransferase 3-like0101
DNA (cytosine-5)-methyltransferase 3A0101
Glutamate 5-kinase0001
Angiotensin-converting enzyme 0101
pregnane X receptor2002
nonstructural protein 11001
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)1001
heat shock protein HSP 90-alpha isoform 20102
Polyunsaturated fatty acid lipoxygenase ALOX15B1001
Guanine nucleotide-binding protein G1001
heat shock protein 90, putative0001
Beta-1 adrenergic receptor 0113
D(1A) dopamine receptor1001
5-hydroxytryptamine receptor 40202
Albumin0112
Cytochrome P450 1A20101
Beta-2 adrenergic receptor0213
ATP-dependent translocase ABCB10202
Beta-1 adrenergic receptor0213
5-hydroxytryptamine receptor 1A0101
Alpha-2A adrenergic receptor0124
Beta-2 adrenergic receptor0203
Cytochrome P450 2C80101
Cytochrome P450 2D60101
Beta-3 adrenergic receptor0213
D(2) dopamine receptor0112
Alpha-1B adrenergic receptor0213
Beta-1 adrenergic receptor0214
Alpha-2C adrenergic receptor0124
D(3) dopamine receptor0101
Muscarinic acetylcholine receptor M30112
D(1A) dopamine receptor0112
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Alpha-1D adrenergic receptor0213
Alpha-1D adrenergic receptor0012
Endothelin-1 receptor0112
Beta-3 adrenergic receptor0202
5-hydroxytryptamine receptor 1B0213
5-hydroxytryptamine receptor 2A0213
5-hydroxytryptamine receptor 2C0213
Neuromedin-K receptor0011
Type-1 angiotensin II receptor0112
Cholecystokinin receptor type A0112
Cytochrome P450 2C190101
5-hydroxytryptamine receptor 70112
Beta-1 adrenergic receptor0101
Alpha-1A adrenergic receptor0124
Alpha-1B adrenergic receptor0012
Mu-type opioid receptor0112
Vasopressin V1a receptor0112
Delta-type opioid receptor0112
Kappa-type opioid receptor0112
5-hydroxytryptamine receptor 2B0213
Alpha-1A adrenergic receptor0213
5-hydroxytryptamine receptor 60213
5-hydroxytryptamine receptor 70101
Cytochrome P450 2J20101
Beta-2 adrenergic receptor0101
Sodium/bile acid cotransporter0101
Beta-2 adrenergic receptor0113
Nuclear receptor subfamily 2 group E member 10022
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR0011
Chain A, Cruzipain1001
ubiquitin carboxyl-terminal hydrolase 2 isoform a1001
Retinol-binding protein 40011
Beta-lactoglobulin0011
Alpha-synuclein0202
Disintegrin and metalloproteinase domain-containing protein 171001
chaperonin-containing TCP-1 beta subunit homolog1001
Estrogen receptor beta0001
Inhibitor of nuclear factor kappa-B kinase subunit beta0001
5'-AMP-activated protein kinase subunit beta-20001
Polymerase acidic protein0011
Stromelysin-10213
Tyrosine-protein phosphatase YopH0101
Aldo-keto reductase family 1 member B10101
Prolyl 4-hydroxylase subunit alpha-10101
Tyrosine-protein phosphatase non-receptor type 10103
Estrogen receptor0001
Prostaglandin G/H synthase 10101
Cystathionine gamma-lyase0101
Prostaglandin G/H synthase 20101
5'-AMP-activated protein kinase subunit gamma-10001
5'-AMP-activated protein kinase catalytic subunit alpha-20001
Xanthine dehydrogenase/oxidase0101
5'-AMP-activated protein kinase catalytic subunit alpha-10001
Carbonic anhydrase0101
Solute carrier family 22 member 70001
Nicotinate phosphoribosyltransferase0101
Ubiquitin-like domain-containing CTD phosphatase 10101
5'-AMP-activated protein kinase subunit gamma-30001
5'-AMP-activated protein kinase subunit gamma-20001
5'-AMP-activated protein kinase subunit beta-10001
Acetylcholinesterase0101
Pyruvate kinase PKM0011
Cholinesterase0101
Caspase-71001
caspase-31001
90-kda heat shock protein beta HSP90 beta, partial0101
estrogen receptor beta isoform 10101
tyrosine-protein phosphatase non-receptor type 7 isoform 20101
Dihydroxyacetone phosphate acyltransferase0001
30S ribosomal protein S60101
30S ribosomal protein S70101
50S ribosomal protein L150101
Tetracycline resistance protein, class B0001
72 kDa type IV collagenase0101
50S ribosomal protein L100101
50S ribosomal protein L110101
50S ribosomal protein L7/L120101
50S ribosomal protein L190101
50S ribosomal protein L10101
50S ribosomal protein L200101
50S ribosomal protein L270101
50S ribosomal protein L280101
50S ribosomal protein L290101
50S ribosomal protein L310101
50S ribosomal protein L31 type B0101
50S ribosomal protein L320101
50S ribosomal protein L330101
50S ribosomal protein L340101
50S ribosomal protein L350101
50S ribosomal protein L360101
30S ribosomal protein S100101
30S ribosomal protein S110101
30S ribosomal protein S120101
30S ribosomal protein S130101
30S ribosomal protein S160101
30S ribosomal protein S180101
30S ribosomal protein S190101
30S ribosomal protein S200101
30S ribosomal protein S20101
30S ribosomal protein S30101
30S ribosomal protein S40101
30S ribosomal protein S50101
30S ribosomal protein S80101
30S ribosomal protein S90101
50S ribosomal protein L130101
50S ribosomal protein L140101
50S ribosomal protein L160101
50S ribosomal protein L230101
30S ribosomal protein S150101
Multidrug transporter MdfA0101
50S ribosomal protein L170101
50S ribosomal protein L210101
50S ribosomal protein L300101
50S ribosomal protein L60101
30S ribosomal protein S140101
30S ribosomal protein S170101
30S ribosomal protein S10101
50S ribosomal protein L180101
Neutrophil collagenase0101
Collagenase 30101
Cannabinoid receptor 10101
50S ribosomal protein L20101
50S ribosomal protein L30101
50S ribosomal protein L240101
50S ribosomal protein L40101
50S ribosomal protein L220101
50S ribosomal protein L50101
30S ribosomal protein S210101
50S ribosomal protein L250101
50S ribosomal protein L36 20101
Integrase 0101
P2Y purinoceptor 120101
Solute carrier family 22 member 70001
Cereblon isoform 40202
cytochrome P450 2D63003
Prostaglandin G/H synthase 10101
Prostaglandin G/H synthase 20101
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0101
DNA-binding protein Ikaros0001
DNA damage-binding protein 10112
Protein cereblon0214
Thymidine kinase 0102
Thymidine kinase, cytosolic0204
Thymidine kinase0102
Thymidine phosphorylase0001
Polyunsaturated fatty acid 5-lipoxygenase0101
Thymidine phosphorylase0001
Thymidylate kinase0101
Thymidine kinase, cytosolic 0002
Thymidine kinase0001
Thymidylate kinase0101
Thymidine kinase 0102
Sterol O-acyltransferase 10101
Thymidine kinase0001
Thymidine kinase0001
Thymidine phosphorylase0101
HLA class I histocompatibility antigen, A alpha chain 0011
Delta0101
Cycloeucalenol cycloisomerase0101
Sterol-8,7-isomerase0101
Chain A, Trp Rna-binding Attenuation Protein0011
Chain K, Trp Rna-binding Attenuation Protein0011
Chain B, tryptophanyl-tRNA synthetase0011
Chain C, Tryptophanyl-tRNA synthetase II0011
Myeloperoxidase0101
Indoleamine 2,3-dioxygenase 10102
Substance-P receptor0101
Tryptophan 2,3-dioxygenase0102
Uracil nucleotide/cysteinyl leukotriene receptor0101
Tryprostatin B synthase0001
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase0011
Chain A, CHORISMATE MUTASE0101
Chain A, TYROSYL-tRNA SYNTHETASE0011
Tubulin--tyrosine ligase0101
Taste receptor type 2 member 140001
RAF proto-oncogene serine/threonine-protein kinase0101
Malate dehydrogenase0101
Serine/threonine-protein kinase B-raf0101
Chymotrypsinogen B0101
Amine oxidase [flavin-containing] B0101
RAC-alpha serine/threonine-protein kinase0101
Dual specificity mitogen-activated protein kinase kinase 20101
Dual specificity mitogen-activated protein kinase kinase 10101
Mitogen-activated protein kinase 140101
MAP kinase-activated protein kinase 50101
caspase 7, apoptosis-related cysteine protease1001
caspase-31001
Urease subunit alpha0101
Urease subunit beta0101
Chain A, Arginase 10101
Multidrug and toxin extrusion protein 20101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]