| Excerpt | Reference |
|---|
| "Convulsions are stopped after anaesthesia with pentobarbitone." | ( Damas, J; Lecomte, J; Lecomte, JH; Piette, JL, 1978) |
| "Seizures are also accompanied by significant reductions in extracellular Ca2+ activity (aCa) to as low as 0." | ( Heinemann, U; Lux, HD, 1978) |
| "Type II (tonic) seizures are invariably associated with profound transient bradycardia, recovery from which begins about the time the tonic seizure phase ends." | ( Beaver, RW; Brauer, RW; Fuquay, J, 1979) |
| "(Time to convulsions is referred to as the induction period, and time between convulsions as the interictal period." | ( Segerbo, BE, 1979) |
| "Included in the convulsions are wild running, tonic-clonic activity, and occasionally death." | ( Philo, R; Reiter, RJ, 1978) |
| "Generalized clonic-tonic seizures are induced by higher volume injections (50 microliter) associated with wider distribution of ouabain, including the cerebellum and brainstem." | ( Barbeau, A; Davidson, DL; Tsukada, Y, 1978) |
| "The hypothesis that convulsions are means to reduce the changes of physical dependence in the central nervous system was not refuted by the present experiments." | ( Wahlström, G, 1976) |
| "The seizures are characterized by running, hopping, and vocalizing and are mixed with shorter-duration tonic episodes." | ( Doerr, JK; Konkol, RJ; Madden, JA, 1992) |
| "Cocaine-induced seizures are common and appear to be due to the local anaesthetic actions of this compound." | ( Djenderedjian, AH; Giombetti, R; Mena, I; Miller, BL; Villanueva-Meyer, J, 1992) |
| "Experimental seizures are followed by an especially rapid and massive induction of brain ornithine decarboxylase (ODC), an enzyme which catalyses the rate-limiting step in the synthesis of polyamines." | ( de Belleroche, JS; Herberg, LJ; Mintz, M; Rose, IC, 1992) |
| "Seizure is a common problem evaluated in pediatric emergency departments." | ( Davis, AT; Nypaver, MM; Reynolds, SL; Tanz, RR, 1992) |
| "Spinal cord seizures are infrequently reported." | ( Cross, LL; Meythaler, JM; Tuel, SM, 1991) |
| "Seizures are a recognized manifestation of neurosarcoidosis, but their clinical relevance is not well established." | ( Krumholz, A; Stern, BJ; Stern, EG, 1991) |
| "We emphasize that convulsions are not infrequent side effect of conditioning regimens including high dose busulfan, and efficient anticonvulsant prophylactic regimens should be used." | ( Berberana, M; De La Camara, R; Fernandez-Rañada, JM; Figuera, A; Tomas, JF, 1991) |
| "Treating seizures is a major part of a neurologic practice." | ( Bernstein, AL, 1990) |
| "Experimental seizures are more readily produced in infant than adult rats, possibly related to a developmental predominance of NMDA receptor-mediated effects." | ( Pasternak, JF; Trommer, BL, 1990) |
| "Eclamptic seizures are clinically and electroencephalographically indistinguishable from generalized tonic-clonic seizures." | ( Fisher, RS; Hanley, DF; Kaplan, PW; Lesser, RP; Repke, JT, 1990) |
| "Seizures are common in acute exacerbations of hepatic porphyria, even though the etiology is not identified in most cases." | ( Deeg, MA; Rajamani, K, 1990) |
| "Seizures are a less frequent, but important complication." | ( Kieburtz, K; Moxley, RT; Ricotta, JJ, 1990) |
| "When partial seizures are identified they are attributed to preceding brain damage, head trauma or stroke." | ( Baulac, M; Laplane, D, 1990) |
| "Convulsive seizures are a potential side effect of antidepressant drug treatment and can be produced by all classes of antidepressants." | ( Ikeda, M; Knapp, RJ; Malatynska, E; Yamamura, HI, 1988) |
| "Pilocarpine seizures are characterized by a sequential development of behavioral patterns and electrographic activity." | ( Bortolotto, ZA; Cavalheiro, EA; Ikonomidou, C; Turski, L; Turski, WA, 1989) |
| "L-allylglycine seizures are associated with generalized decreases in regional GABA levels, and increases in regional glutamine levels." | ( Chapman, AG, 1985) |
| "Neocortical focal seizures are characterized by motor jerks in one limb (Jacksonian type), head turning (adversive attack), or localized sensory manifestations, and limbic or psychomotor attacks by brief impairment of consciousness and often by motor automatisms." | ( Hess, CW, 1988) |
| "Febrile seizures are common in children." | ( Wright, SW, 1987) |
| "Tetanic convulsions are not uncommon among severely dehydrated children in the developing countries." | ( Aperia, A; Butt, KS; Khan, SR; Lindblad, BS; Murtaza, A, 1988) |
| "The occurrence of convulsions is not in keeping with the results of animal experiments, studies of epileptic patients treated with nomifensine or observations made following overdoses of this drug." | ( Edwards, JG; Glen-Bott, M, 1987) |
| "Convulsions are characteristic of magnesium deficiency and hypocalcemia." | ( Chaistitwanich, R; Hendricks, DG; Mahoney, AW; Sisson, DV, 1987) |
| "The seizures are characterized by one or two wild running fits which terminate in a tonic dorsiflexion with open mouth, followed by a catatonic state." | ( Depaulis, A; Kiesmann, M; Marescaux, C; Micheletti, G; Vergnes, M; Warter, JM, 1987) |
| "Bilateral seizures are obtained after about 15 stimulations of the amygdala in the rat." | ( LeGal La Salle, G; Papy, JJ; Rougier, I; Vion-Dury, J, 1986) |
| "Febrile seizures are a common problem." | ( Ater, SB; Bettis, DB, 1985) |
| "These seizures are characterized by tonic spasm in the extremities, often accompanied by painful dysesthesias, and are fleeting, usually lasting no more than two minutes." | ( Cherrick, AA; Ellenberg, M, 1986) |
| "Seizures are an occasional manifestation of phenytoin toxicity, particularly when levels are high." | ( Masdeu, JC; Stilman, N, 1985) |
| "Her seizures are now treated successfully with phenytoin." | ( Soman, M; Swenson, C, 1985) |
| "L-Allylglycine seizures are associated with generalized decreases in GABA concentrations (-32 to -54%), increases in glutamine concentrations (+10 to +53%), and a decrease in cortical aspartate concentration (-14%)." | ( Chapman, AG; Meldrum, BS; Premachandra, M; Westerberg, E, 1984) |
| "The occurrence of convulsions is not in keeping with the results of animal experiments and of clinical trials in which epileptic patients were included, both of which suggest that viloxazine does not have epileptogenic properties and may have anticonvulsant actions." | ( Edwards, JG; Glen-Bott, M, 1984) |
| "Seizures are a common occurrence in patients who are dependent on alcohol." | ( McMicken, D, 1984) |
| "Penicillin induced seizures are not affected by furosemide." | ( Kariv, N; Noy, S; Rubinstein, E; Schtacher, G, 1984) |
| "These convulsions are tonic-clonic." | ( Colombo, R; Ossi, C; Pinelli, A; Spazzi, L; Tofanetti, O, 1984) |
| "The 'typical' T4-T7 seizure is a scratch reflex followed by the tonic-clonic seizure lasting for 20-30 s and ending with a scratch afterdischarge lasting for several minutes." | ( Chambers, WW; Chen, WP; Herdman, SJ; Liu, CN; Yu, J, 1984) |
| "These seizures are indistinguishable in quality from those induced by pentylenetetrazol (PTZ), and pretreatment with low doses of caffeine potentiates PTZ-induced seizures." | ( Marangos, PJ; Martino, AM; Paul, SM; Skolnick, P, 1981) |
| "Sound-induced seizures are suppressed by the i." | ( Croucher, MJ; Krogsgaard-Larsen, P; Meldrum, BS, 1983) |
| "Brainstem-triggered convulsions are generalized convulsive seizures produced by direct electrical stimulation of the mesencephalic reticular formation." | ( Burnham, WM; Chiu, P, 1982) |
| "Febrile seizures are a common pediatric problem, yet there is a great deal of disagreement about the appropriate diagnostic evaluation of a child with this disorder." | ( Berliner, BC; Gerber, MA, 1981) |
| "Kynurenine seizures are suggested to be related to the action of kynurenine on glycine receptors in the central nervous system." | ( Lapin, IP, 1981) |
| "Catamenial seizures are defined as epileptic seizures occurring during distinct phases of the menstrual cycle (i." | ( Bauer, J; Elger, CE; Hocke, A, 1995) |
| "Drug-induced seizures are a potentially serious adverse effect." | ( Chatel, DM; Dahdal, WY; Franson, KL; Grossberg, GT; Hay, DP; Kotegal, S; Mirza, WU; Neppe, V; Szwabo, PA, 1995) |
| "Initially seizures are discrete, then undergo waxing-and-waning of convulsive/electroencephalographic severity." | ( Handforth, A; Treiman, DM, 1995) |
| "Stimuli that evoke seizure are capable of inducing structural changes in the hippocampus." | ( Bauer, J; Fischer, B; Platt, D; Popa-Wagner, A; Retchkiman, I, 1995) |
| "Seizures are a recognized complication of human immunodeficiency virus (HIV)-type-1 infection." | ( Bodian, C; Maker, H; Van Paesschen, W, 1995) |
| "Audiogenic seizures are evoked by acoustic stimulation in susceptible (S) but not in resistant (R) rats." | ( Antunes-Rodrigues, J; Garcia-Cairasco, N; Oliveira, JA; Reis, LC; Terra, VC, 1994) |
| "Amygdala-kindled seizures are more potently inhibited by phenytoin than by magnesium sulfate." | ( Cotton, DB; Irtenkauf, SM; Mason, B; Standley, CA; Stewart, L, 1994) |
| "Since limbic seizures are a more injurious stimulus, the KROX-20 expression profile was investigated in adult rats subjected to kainic acid induced limbic epilepsy at postictal intervals up to 48 h." | ( Bravo, R; Gass, P; Herdegen, T; Kiessling, M, 1994) |
| "Convulsions are described as an infrequent complication with this therapy in the non-pregnant population." | ( DeChazal, R; Halligan, A; Nan, A; Taylor, D, 1993) |
| "The mechanisms of convulsions are not clear." | ( Andou, Y; Koyama, K; Matsuo, H; Saruki, K, 1994) |
| "Seizures are a rare complication after myelography with the current nonionic contrast agents and have not been previously reported in the emergency medicine literature." | ( Olsen, J, 1994) |
| "Such seizures are more likely in the elderly, in the presence of pre-existing neurological disease, and when theophylline is given with certain antibiotics and cimetidine." | ( FitzGerald, MX; Hutchinson, J; Hutchinson, M; O'Riordan, JI, 1994) |
| "Seizures are uncommon, but serious, adverse effects of antidepressant drugs." | ( Jacobs, SC; Nelson, JC; Rosenstein, DL, 1993) |
| "These seizures are characterized by running/bouncing clonus and tonic extensor convulsions." | ( Bettendorf, AF; Browning, RA; Burger, RL; Jobe, PC; Mishra, PK, 1994) |
| "Most such seizures are related to acute abstinence from chronic, high doses of alcohol use." | ( Earnest, MP, 1993) |
| "Convulsions are frequently observed in severe, acute cyanide intoxication." | ( Cassel, GE, 1995) |
| "Generalised or partial seizures are a common problem with many supratentorial gliomas." | ( Beaumont, A; Clarke, M; Whittle, IR, 1996) |
| "Epileptic seizures are thought to terminate largely as a result of the extracellular accumulation of the purinergic neuromodulator, adenosine, released by discharging neurons." | ( Engelbrecht, AH; Herberg, LJ; Kellaway, L; Lamm, MC; Mintz, M; Russell, VA; Taljaard, JJ, 1996) |
| "Altitude convulsion is a rather specific form of experimental convulsion which is induced by acute exposure to a hypobaric hypoxic condition." | ( Chen, AC; Chen, CH; Liu, HJ, 1997) |
| "Convulsive seizures are among the most common problems involving the central nervous system." | ( Kraus, D; Schmolke, M; Thomasius, R, 1997) |
| "Pilocarpine-induced seizures are initiated via muscarinic receptors and further mediated via NMDA receptors." | ( Ebinger, G; Khan, GM; Manil, J; Michotte, Y; Smolders, I, 1997) |
| "Seizures are common in patients infected with human immunodeficiency virus (HIV)." | ( Dasgupta, A; McLemore, JL, 1998) |
| "The SNR effects on seizures are site-specific within the SNR and developmentally regulated." | ( Löscher, W; Moshé, SL; Velísková, J, 1998) |
| "In rodents these seizures are readily triggered by sound (audiogenic seizures)." | ( Faingold, CL; N'Gouemo, P; Riaz, A, 1998) |
| "Generalized epileptic seizures are underlied by specific circuits where GABAergic synapses are involved at different levels." | ( Depaulis, A; Deransart, C; Marescaux, C; Vergnes, M, 1997) |
| "Seizures are commonly encountered in patients who do not have epilepsy." | ( Delanty, N; French, JA; Vaughan, CJ, 1998) |
| "Because cocaine seizures are relatively uncommon, they should be diagnosed by exclusion and a neurological workup to rule out central nervous system (CNS) catastrophe should be made." | ( Blaho, K; Geraci, S; Logan, B; Winbery, S, 1998) |
| "Partial seizures are usually due to a structural cerebrocortical lesion and may be simple or complex." | ( March, PA, 1998) |
| "Seizure is the primary adverse reaction associated with bupropion overdoses." | ( Paris, PA; Saucier, JR, 1998) |
| "Whereas neonatal seizures are a predictor of adverse neurological outcome, there is controversy regarding whether seizures simply reflect an underlying brain injury or can cause damage." | ( Ben-Ari, Y; Chevassus-Au-Louis, N; Gairsa, JL; Holmes, GL, 1998) |
| "New-onset seizures are infrequent in patients with HIV." | ( Barrio, JL; Domingo, P; Escartin, A; Fuster, M; Iranzo, A; Marti-Fàbregas, J; Pascual-Sedano, B; Sambeat, MA, 1999) |
| "Seizures are common after severe cerebral ischemia." | ( Kim, DC; Todd, MM, 1999) |
| "Epileptic seizures are associated with increases in hippocampal excitability, but the mechanisms that render the hippocampus hyperexcitable chronically (in epilepsy) or acutely (in status epilepticus) are poorly understood." | ( Basbaum, AI; Cao, Y; Liu, H; Mazarati, AM; Sankar, R; Wasterlain, CG, 1999) |
| "Partial onset seizures are more frequent among hazardous drinkers than hitherto recognized." | ( Bovim, G; Bråthen, G; Brodtkorb, E; Helde, G; Sand, T, 1999) |
| "Seizures are a frequent problem confronting EMS personnel." | ( Nicholl, JS, 1999) |
| "Tonic and clonic seizures are abolished at 15 min (ED(50s) 0." | ( Chapman, AG; Meldrum, BS; Nanan, K; Yip, P, 1999) |
| "Although seizures are very common in neonates and are often the harbinger of poor neurologic outcome, there is controversy regarding the degree of brain damage induced by seizures during early development." | ( Holmes, GL; Schmid, R; Stafstrom, CE; Tandon, P, 1999) |
| "Nicotine-induced seizures are centrally mediated and involve the activation of alpha7 along with other nicotinic receptor subunits." | ( Damaj, MI; Dukat, M; Glassco, W; Martin, BR, 1999) |
| "Conclusion Atypical absence seizures are common in glucose transporter type 1 deficiency and should alert the clinician to the possibility of this treatable disorder when present in a young child with developmental delay." | ( Boles, RG; Kollros, PR; Mitchell, WG; Mofidi, S; Novotny, EJ; Seashore, MR, 1999) |
| "Postoperative epileptic seizures are recognised but rare." | ( Enright, SM; Goulding, PJ; Reuber, M, 2000) |
| "All patients' seizures are fully controlled on once-a-day low-dose phenobarbital with no side effects." | ( Lerman, P; Lerman-Sagie, T, 1999) |
| "Seizures are a well known consequence of human cocaine abuse, and in rodent models, sensitivity to cocaine seizures has been shown to be strongly influenced by genotype." | ( Belknap, JK; Bergeson, SE; Crabbe, JC; Hain, HS, 2000) |
| "Seizures is a major toxicity of theophylline." | ( Gupta, YK; Malhotra, J, 1998) |
| "Seizures are also often associated with tics and compulsions, which likewise involve cortical-limbic hyperactivity." | ( Burton, FH; Campbell, KM; McGrath, MJ; Veldman, MB, 2000) |
| "Experimental absence seizures are associated with perturbations in the presynaptic release of GABA and glutamate within thalamocortical circuitry." | ( Banerjee, PK; Burnham, M; Hampson, D; Snead, OC, 2000) |
| "The threshold for seizures is lowered by tramadol." | ( Levine, BS; Pestaner, JP; Ripple, MG; Smialek, JE, 2000) |
| "Epileptic seizures are often not the main problem in atypical rolandic epilepsies like CSWS or LKS and the amelioration of cognitive dysfunction by epileptic discharge is the prominent aim of an AED therapy." | ( Rating, D, 2000) |
| "Although neonatal seizures are quite common, there is controversy regarding their consequences." | ( Cha, BH; Cilio, MR; Holmes, GL; Liu, X; McCabe, BK; Silveira, DC; Sogawa, Y, 2001) |
| "Convulsions are well-known complications of local anesthetics." | ( Alardo, JP; Bisschop, DY; Germain, ML; Just, BY; Millart, HG; Razgallah, B; Trenque, TC, 2001) |
| "Febrile seizures are the most common seizures in childhood and, like all seizures, can be frightening to witness." | ( Baumann, RJ, 2001) |
| "Subtle seizures are mild paroxysmal alterations in motor or autonomic activity and are unique to the neonatal period." | ( Aggarwal, R; Deorari, AK; Paul, VK; Upadhyay, A, 2001) |
| "Seizures are associated with pronounced changes in regional cerebral blood flow." | ( Borbély, K, 2001) |
| "Seizures are commonly associated with hypoxic-ischemic encephalopathy." | ( Armstrong, DL; Battin, MR, 2001) |
| "Convulsions are a common complication of severe malaria in children and are associated with poor outcome." | ( Crawley, J; Edwards, G; Kokwaro, GO; Marsh, K; Muchohi, SN; Newton, CR; Ogutu, BR; Otieno, GO, 2002) |
| "Epileptic seizures are followed by dynamic alterations in neurological function in the postictal period." | ( Baumgartner, C; Leutmezer, F, 2002) |
| "Other childhood seizures are also responsive to ACTH." | ( Burnham, WM; Edwards, HE; Vimal, S, 2002) |
| "Pilocarpine-induced seizures are mediated by the M(1) subtype of muscarinic acetylcholine receptor (mAChR), but little is known about the signaling mechanisms linking the receptor to seizures." | ( Berkeley, JL; Decker, MJ; Levey, AI, 2002) |
| "Seizure is a recognized complication of high-dose busulfan (BU) therapy and phenytoin (DPH) is widely used as prophylaxis." | ( Chan, KW; Choroszy, M; Koontz, S; Mullen, CA; Slopis, J; Tran, H; Worth, LL, 2002) |
| "The new onset seizure is then the manifestation of this abnormality." | ( Martinus, I; Modi, G; Modi, M; Vangu, M, 2002) |
| "Flurothyl-induced convulsions are associated with GABA receptors; hence, benzodiazepine (BDP) suppression may result from the strong relation between BDP and GABAnergic neurons." | ( Araki, H; Futagami, K; Gomita, Y; Hashimoto, Y; Kawasaki, H; Kobayashi, Y, 2002) |
| "Seizures are an uncommon but serious complication of hyponatremia which can lead to permanent brain damage and even death." | ( Tokeshi, J; Youn, KS, 2002) |
| "Severity of tonic convulsive seizures is a determinant of disordered cardiac autonomic regulation and directly influences the duration of cardiac arrhythmia during the immediate postictal state following MES." | ( Casebeer, D; Darbin, O; Naritoku, DK, 2003) |
| "Epileptic seizures are associated with neuronal hyperactivity." | ( Bikson, M; Fox, JE; Hahn, PJ; Jefferys, JG, 2003) |
| "Such seizures are more common among adolescents." | ( Bailine, SH; Doft, M; Lui, G; Petrides, G, 2003) |
| "The seizures are resistant to conventional anticonvulsants." | ( Akre, B; Lundby, R; Rasmussen, M, 2004) |
| "Some electrographic seizures are generated intracortically." | ( Grenier, F; Steriade, M; Timofeev, I, 2004) |
| "Generalized seizures are commonly thought to involve the entire brain homogeneously." | ( Blumenfeld, H; McNally, KA, 2004) |
| "Convulsions are major and life-threatening signs of organophosphate (OP) nerve agents induced neurotoxicity." | ( Auta, J; Costa, E; Davis, J; Guidotti, A, 2004) |
| "Second, that the seizure is not inherently harmful but is, instead, associated with massive intracerebral circulatory changes that are intended to restore impaired mitochondrial function." | ( Doman, G; Pelligra, R, 2004) |
| "Seizures are reported to occur more frequently among children with diagnoses of autism and pervasive developmental disorder (PDD), and some reports indicate a frequency as high as 30%." | ( Castello, FV; Mehta, UC; Patel, I, 2004) |
| "Hypocalcemic seizures are uncommon and underdiagnosed complications of long-term therapy with AEDs." | ( Al-Busairi, WA; Al-Bustan, MA; Al-Mulla, FA; Ali, FE, 2004) |
| "Neonatal seizures are the most common manifestation of underlying cerebral dysfunction." | ( Armstrong, EA; Jaharus, C; Saucier, DM; Wirrell, EC; Yager, JY, 2004) |
| "Seizures are both caused by and induce a complex set of neurobiological alterations and adaptations." | ( Post, RM, 2004) |
| "Convulsions are common complications of shigellosis in children." | ( Ashkenazi, S; Chrousos, GP; Ovadia, H; Weizman, A; Yuhas, Y, 2004) |
| "Experimental seizures are often accompanied by the generation of free radicals that cause lipid peroxidation (LPO), which may subsequently cause neurodegeneration observed in certain types of human epilepsy." | ( Rajasekaran, K, 2005) |
| "Generalized tonic-clonic seizures are a rare complication of levofloxacin therapy." | ( Christie, MJ; Sikaneta, TG; Tam, PY; Ting, RH; Wong, K, 2005) |
| "Dyskinesias and seizures are both medically refractory disorders for which cannabinoid-based treatments have shown early promise as primary or adjunctive therapy." | ( Adrian, R; Baratta, J; Giuffrida, A; Piomelli, D; Solbrig, MV, 2005) |
| "Seizures are an important adverse effect of bupropion and care is needed when used in other conditions or with other medication that can lower the seizure threshold." | ( Ross, S; Williams, D, 2005) |
| "The induction of a seizure is a core event in successful ECT." | ( Amiaz, R; Aronov, S; Etchin, A; Grunhaus, L; Vishne, T, 2005) |
| "Diagnosis of epileptic seizures is largely dependent on the clinical history." | ( Mackay, M, 2005) |
| "Centrally mediated seizures are a common consequence of exposure to organophosphates (OP) despite conventional treatment with atropine and an oxime." | ( Chapman, S; Gilat, E; Kadar, T, 2006) |
| "Seizures are a common complication of primary (PBT) and metastatic (MBT) brain tumors, affecting approximately 50% of all patients during the course of their illness." | ( Goldlust, SA; Newton, HB; Pearl, D, 2006) |
| "Seizures are a common neurologic symptom of tuberous sclerosis complex." | ( Chuck, G; Collins, JJ; Franz, DN; Leonard, JM; Tudor, C, 2006) |
| "Seizures are the most common clinical manifestation and may be exacerbated by phenobarbitone." | ( Appleton, DB; Bowling, FG; Burke, CJ; Coman, DJ; De Vivo, DC; McGill, JJ; O'Neil, CM; Pelekanos, JT; Sinclair, KG; Wallace, GB; Wang, D, 2006) |
| "Most neonatal seizures are triggered by acute illness such as hypoxic-ischemic encephalopathy, stroke, or infection; rarely are they triggered by epilepsy per se." | ( Clancy, RR, 2006) |
| "Early postoperative seizures are defined as those that appear within the first week after surgery and are a well-known and feared complication in patients with supratentorial brain tumors." | ( Bomprezzi, C; Formica, F; Iacoangeli, M; Mauro, AM; Morresi, S; Provinciali, L; Scerrati, M, 2007) |
| "Neonatal seizures are most commonly incited by serious acute illnesses such as hypoxic-ischemic encephalopathy, birth trauma, or infection." | ( Clancy, RR, 2006) |
| "Seizures are a common complication of metastatic brain tumors (MBT), affecting approximately 27-50% of all patients during the course of their illness." | ( Dalton, J; Goldlust, S; Newton, HB; Pearl, D, 2007) |
| "Seizures are a rare complication during cerebral angiographic procedures." | ( Nwagwu, CI; Westhout, FD, 2007) |
| "Kindled seizures are widely used to model epileptogenesis, but the molecular mechanisms underlying the attainment of kindling status are largely unknown." | ( Dunoiu, C; Ioana, M; Mogoantă, L; Petcu, EB; Pirici, D; Popa-Wagner, A, 2007) |
| "Seizures are a common occurrence in the neonatal intensive care unit, especially among low-birth-weight infants." | ( Rotenberg, JS; Shoemaker, MT, 2007) |
| "Sevoflurane-induced seizures are most often described during mask induction of anesthesia when high concentrations of the volatile agent are administered concomitant with alveolar hyperventilation." | ( Iqbal, Z; Kumar, V; Markan, S; Mohanram, A; Pagel, PS, 2007) |
| "Seizures are a major complication of viral encephalitis." | ( Campbell, IL; Getts, DR; Getts, MT; King, NJ; Matsumoto, I; Müller, M; Radford, J; Shrestha, B, 2007) |
| "A potential role in seizures is suggested by Newton et al." | ( Atassi, H; Croll, SD; Elkady, A; Goodman, JH; Hylton, D; McCloskey, DP; Nicoletti, JN; Rudge, JS; Scharfman, HE; Shah, SK, 2008) |
| "Although seizures are very common during early brain development, consequences of seizures during this age period are less severe than in the mature brain." | ( Stafstrom, CE, 2007) |
| "Prevention of seizures is needed when HBO is used as preconditioning method." | ( Li, J; Liu, K; Liu, W; Sun, X; Tao, H; Xu, W; Zhang, JH, 2008) |
| "Early onset of seizures is linked to the combined MECP2 and BDNF genotypes." | ( Bahi-Buisson, N; Bienvenu, T; Chelly, J; Coste, J; De Roux, N; Guellec, I; Nectoux, J; Rosas, H; Tardieu, M, 2008) |
| "Tardive seizure is a serious adverse reaction of electroconvulsive therapy (ECT)." | ( Isse, K; Nakamura, M; Saito, T; Watari, M, 2008) |
| "Epileptiform seizures are most common during the neonatal period, affecting at least 0." | ( Bari, F; Domoki, F; Zimmermann, A, 2008) |
| "Whereas propagated seizures are known to disrupt cerebral activity, little work has been done on remote network effects of seizures that do not propagate." | ( Blumenfeld, H; Englot, DJ; Herman, P; Hyder, F; Mansuripur, PK; Mishra, AM, 2008) |
| "Seizures are a recognized complication of citalopram overdose." | ( Graham, A; Gray, JA; Waring, WS, 2008) |
| "Generalized seizures are an important manifestation of citalopram toxicity, and cannot be explained solely by electrolyte disturbances or co-ingestion of other drugs or ethanol." | ( Graham, A; Gray, JA; Waring, WS, 2008) |
| "Seizures are common in patients with gliomas, and phenytoin (PHT) is frequently used to control tumor-related seizures." | ( Barbaro, N; Burt, M; Chakalian, L; Chang, E; Chang, S; Lamborn, KR; Lim, DA; McDermott, MW; Tarapore, P, 2009) |
| "Neonatal seizures are one of the most common neurological disorders in infants." | ( Blume, HK; Christakis, DA; Garrison, MM, 2009) |
| "Seizure is the most common paediatric neurological disease which occurs in ten percent of children." | ( Fallah, R; Karbasi, SA; Mosadegh, MM, 2009) |
| "Epileptic seizures are a common clinical problem in children with brain tumors." | ( Attinà, G; Battaglia, D; Mastrangelo, S; Riccardi, R; Rizzo, D; Ruggiero, A, 2010) |
| "Seizures are a recognized complication of acute overdose with the racemic (1:1 ratio of R- and S-enantiomers) selective serotonin reuptake inhibitor antidepressant citalopram." | ( Bauer, K; Ceschi, A; Gerber-Zupan, G; Hackl, E; Hoffmann-Walbeck, P; Kullak-Ublick, GA; Kupferschmidt, H; Prasa, D; Rauber-Lüthy, C; Sauer, O; Seidel, C; Stedtler, U; Wilks, M; Yilmaz, Z, 2010) |
| "Seizures are a frequently reported adverse effect of bupropion in therapeutic oral doses; however, there are limited data about the consequences of nasal insufflation of bupropion." | ( Kim, D; Steinhart, B, 2010) |
| "Neonatal seizures are associated with a high likelihood of adverse neurological outcomes, including mental retardation, behavioral disorders, and epilepsy." | ( Holmes, GL; Isaev, D; Isaeva, E; Khazipov, R; Savrasova, A, 2010) |
| "Seizures are a common phenotype in all of these neurological disorders, yet the underlying molecular mechanism(s) of seizure induction and propagation remain largely unknown." | ( Malter, JS; Westmark, CJ; Westmark, PR, 2010) |
| "EEG seizures are associated with prolonged deep hypothermic circulatory arrest and with adverse long-term neurodevelopmental outcomes." | ( Andropoulos, DB; Dickerson, HA; Fraser, CD; Heinle, JS; Hrachovy, RA; McKenzie, ED; Meador, MR; Mizrahi, EM; Stark, AR; Stayer, SA, 2010) |
| "EEG seizures are infrequent in neonates undergoing surgery with high-flow CPB." | ( Andropoulos, DB; Dickerson, HA; Fraser, CD; Heinle, JS; Hrachovy, RA; McKenzie, ED; Meador, MR; Mizrahi, EM; Stark, AR; Stayer, SA, 2010) |
| "A Prolonged convulsive seizure is the most common neurological medical emergency with poor outcome." | ( Ashrafi, MR; Bavarian, B; Karimi, P; Khosroshahi, N; Kompani, F; Malamiri, RA; Mirzaei, M; Zarch, AV, 2010) |
| "Subtle seizures are the commonest type of seizures occurring in the neonatal period." | ( Agarwal, R; Deorari, A; Paul, VK; Sankar, JM, 2010) |
| "Seizures are a common sequela of self-poisoning." | ( Eddleston, M; Shah, AS, 2010) |
| "Seizures are reported as an uncommon side effect of interferon therapy." | ( Ahmed, F; Albert, C; Brand, M; Brass, C; Brown, R; Fixelle, AM; Herrera, JL; Jacobson, IM; Rustgi, VK; Wasserman, RB, 2011) |
| "Neonatal seizures are common, especially in prematurity." | ( Dinger, J; Ikonomidou, C; Ramantani, G; Rating, D; Walter, B, 2011) |
| "Eating-induced seizures are an uncommon presentation of reflex epilepsy, a condition characterized by seizures provoked by specific stimuli." | ( Friedman, DE; Kung, DH; Manyam, SC; Newmark, ME; Rhodes, LB, 2010) |
| "Considering that seizures are precipitated by common infections in children with GA-I, we investigated whether lipopolysaccharide (LPS) modifies GA-induced electrographic and neurochemical alterations in 21 days-old rats." | ( Ferreira, J; Fighera, MR; Furian, AF; Magni, DV; Mello, CF; Oliveira, AP; Oliveira, MS; Royes, LF; Santos, AR; Souza, MA, 2011) |
| "Neonatal seizures are often refractory to treatment with initial antiseizure medications." | ( Abend, NS; Clancy, RR; Dlugos, DJ; Gutierrez-Colina, AM; Monk, HM, 2011) |
| "Both types of seizures are suppressed by VB(6)." | ( Ohtahara, S; Ohtsuka, Y; Yamatogi, Y, 2011) |
| "Acute seizures are readily recognizable episodes requiring urgent treatment." | ( Chen, YI; Chiang, LM; Chou, ML; Deng, ST; Hung, PC; Lin, KL; Shen, HH; Tseng, CH; Wang, HS, 2011) |
| "Seizures are induced in some patients even at low doses." | ( Beasley, DM; Gee, P; Schep, LJ; Slaughter, RJ; Vale, JA, 2011) |
| "While early-life seizures are considered a major cause for cognitive impairment, it is not known whether it is the seizures, the underlying neurological substrate or a combination that has the largest impact on eventual learning and memory." | ( Holmes, GL; Lenck-Santini, PP; Lucas, MM; Scott, RC, 2011) |
| "In these models epileptic seizures are triggered either by external stimuli (reflex epilepsies) or by internal fluctuations." | ( Kalitzin, S; Koppert, MM; Lopes da Silva, FH; Viergever, MA, 2011) |
| "The incidence of seizures is particularly high in the early ages of life." | ( Briggs, SW; Galanopoulou, AS, 2011) |
| "Seizures are a common symptom of brain tumours." | ( Grant, R; Kerrigan, S, 2011) |
| "An epileptic seizure is reported in a 38-year-old woman, known to be an epileptic patient." | ( Skalli, S; Soulaymani Bencheikh, R, 2011) |
| "Psychogenic nonepileptic seizures are clinical events that mimic epileptic seizures but are not associated with electroencephalographic discharges." | ( Dubois-Teklali, F; Spitz, MA; Vercueil, L, 2012) |
| "Seizures are common in critically ill patients and can impact morbidity and mortality." | ( Cherry, S; Elzawahry, H; Judd, L; LaRoche, S; Muniz, JC, 2012) |
| "The incidence of seizures is generally accepted to be greater in patients with multiple sclerosis (MS) than in the general population, and rarely, MS can initially present as seizure." | ( Kendrick-Adey, AC; Sponsler, JL, 2011) |
| "Seizures are a common complication in patients with central nervous system (CNS) tumors." | ( O'Reilly, M; Twomey, M; Wallace, EM, 2012) |
| "Conversely, seizures are sensitive to changes in sex hormone levels, which in turn may affect the seizure-induced neuronal damage." | ( Desantis, KA; Velíšková, J, 2013) |
| "Seizures are markedly drug resistant and few reports have suggested the efficacy of some antiepileptic drugs." | ( Auvin, S; Bellavoine, V; Delanoë, C; Mahfoufi, N; Merdariu, D, 2013) |
| "Neonatal seizures are common and often reflect a severe underlying neurologic dysfunction in neonates." | ( Huang, LT; Lai, MC; Tain, YL; Yang, SN, 2012) |
| "Drug-induced seizures are in view of a constantly ageing population and increasingly frequent polypharmacotherapy an increasing problem in daily routine praxis." | ( Block, F; Dafotakis, M, 2013) |
| "Seizures are the manifestation of highly synchronized burst firing of a large population of cortical neurons." | ( Abramowitz, J; Birnbaumer, L; Flockerzi, V; Freichel, M; Gottschall, PE; Howell, MD; Phelan, KD; Rhee, SW; Shwe, UT; Wu, H; Zheng, F, 2013) |
| "Seizures are a potentially devastating complication of resection of brain tumors." | ( Forman, A; Graham, S; Heimberger, AB; Hess, K; Lang, FF; McCutcheon, IE; Prabhu, SS; Qiao, W; Sawaya, R; Suki, D; Trinh, VT; Wang, X; Weinberg, JS; Wu, AS, 2013) |
| "When (sub)clinical seizures are treated, there is no consensus about the most appropriate treatment for neonatal seizures and how to assess the efficacy of treatment." | ( de Vries, LS; Hellström-Westas, L; van Rooij, LG, 2013) |
| "While seizures are usually intractable to medication in tuberous sclerosis complex (TSC), a common genetic cause of epilepsy, vigabatrin appears to have unique efficacy for epilepsy in TSC." | ( McDaniel, SS; Rensing, NR; Wong, M; Zhang, B, 2013) |
| "Neonatal seizures are a naturally occurring source of neuronal overactivation and can lead to long-term epilepsy and cognitive deficits." | ( Jensen, FE; Klein, PM; Kosaras, B; Sun, H, 2013) |
| "On the one hand, seizures are associated with excessive neuronal activity that can spread across the brain, suggesting run-away excitation." | ( Grasse, DW; Karunakaran, S; Moxon, KA, 2013) |
| "Its effect on seizures is complex." | ( Bråthen, G; Brodtkorb, E; Helde, G; Reimers, A; Samsonsen, C, 2013) |
| "Tardive seizures are typically associated with electroencephalographic evidence of ictal activity and motor manifestations of the tonic-clonic activity." | ( Karim, Y; McCormick, LM; Thisayakorn, P; Yamada, T, 2014) |
| "Neonatal seizures are common in the first month of life and may impair neurodevelopmental outcome." | ( Cipriani, C; Crisp, E; Khan, O; Kirmani, B; Wright, C, 2013) |
| "Febrile seizure is common in young children, and the use of non-steroidal anti-inflammatory drugs for febrile seizure is not recommended." | ( Baik, EJ; Chung, JI; Kim, AY; Lee, SH, 2013) |
| "Neonatal seizures are a potentially life-threatening pediatric problem with a variety of causes, such as birth trauma, asphyxia, congenital anomalies, metabolic disturbances, infections, and drug withdrawal or intoxication." | ( Chen, L; Langhan, ML; Thornton, MD, 2013) |
| "Seizure is estimated to be the presenting symptom of pulmonary embolism (PE) < 1% of the time." | ( Jasani, N; Volz, EE, 2014) |
| "Although seizures are known to be harmful, recent evidence indicates that they can also lead to adaptations that protect neurons from further insult." | ( Friedman, L; Hu, S, 2014) |
| "Neonatal seizures are often refractory to treatment with initial antiseizure medications." | ( Ariguloglu, EA; Koklu, E; Koklu, S, 2014) |
| "Seizures are rare but well known side-effects of carbapenems, especially imipenem." | ( Beovic, B; Maticic, M; Soštaric, N, 2014) |
| "Epileptic seizures are well-known neurological complications following stroke, occurring in 3% of patients." | ( Chen, JG; Guan, XL; He, JG; Hu, ZL; Luo, Y; Wang, F; Wu, PF; Xiao, W; Zhang, JT; Zhou, J, 2014) |
| "Seizures are currently defined by their electrographic features." | ( Bennet, KE; Blaha, CD; Bower, MR; Chang, SY; Goerss, SJ; Kim, I; Lee, KH; Marsh, WR; Meyer, FB; Stead, M; Van Gompel, JJ; Worrell, GA, 2014) |
| "Convulsive seizures are a serious postoperative complication after cardiac surgery." | ( Carroll, J; Djaiani, G; Garrido-Olivares, L; Jerath, A; Katznelson, R; Rao, V; Sharma, V; Wasowicz, M, 2014) |
| "Animal modeling of seizure is invaluable to contribute to the mechanistic understanding of punctual seizure event, and those that triggered in an immature neural network could alter the mature brain physiology." | ( Da Silva, RS; Menezes, FP; Rico, EP, 2014) |
| "Seizures are a common manifestation of acute neurologic insults in neonates and are often resistant to the standard antiepileptic drugs that are efficacious in children and adults." | ( Kahle, KT; Kaila, K; Puskarjov, M; Ruusuvuori, E, 2014) |
| "Seizures are the primary clinical manifestation which could be acute (secondary to active lesions) or remote symptomatic (due to calcified lesions)." | ( Chakrabarty, B; Gulati, S; Gupta, AK; Jain, P; Kumar, A; Pandey, RM; Sachan, D, 2014) |
| "Flurothyl induced seizures are clinically as effective without the memory effects associated with electricity." | ( Cooper, K; Fink, M, 2014) |
| "Seizures are a frequent complication of brain injury, including intracerebral hemorrhage (ICH), where seizures occur in about a third of patients." | ( Colbourne, F; Dickson, CT; Klahr, AC, 2015) |
| "Seizures are a common symptom in patients with low-grade glioma (LGG), negatively influencing quality of life, if uncontrolled." | ( Dirven, L; Heimans, JJ; Koekkoek, JA; Postma, TJ; Reijneveld, JC; Taphoorn, MJ; Vos, MJ, 2015) |
| "Clinical seizures are common intraoperative and postoperative complications of supratentorial craniotomies with intraoperative brain mapping." | ( Bello, L; Carrabba, G; Colombo, A; Conte, V; L'Acqua, C; Magni, L; Magnoni, S; Stocchetti, N, 2015) |
| "Kainate-induced seizures are accompanied by leukotriene formation, and are reduced by inhibitors of LOX/COX pathway." | ( Arroyo, DS; Iribarren, P; Jesse, AC; Lenz, QF; Marafiga, JR; Masson, CJ; Mello, CF; Poersch, AB; Reschke, CR; Temp, FR, 2014) |
| "Seizures are a common cause of neurologic disease, and phenobarbital (PB) is the most commonly used antiepileptic drug." | ( Barnes Heller, HL; Delamaide Gasper, JA; Robertson, M; Trepanier, LA, 2015) |
| "Anxiety and seizures are closely similar neurobehavioral disorders and are regulated by limbic system." | ( Gulati, K; Ray, A, 2014) |
| "Seizures are common but are self-limited." | ( Albertson, TE; Ford, JB; Lewis, JC; Owen, KP; Sutter, ME, 2014) |
| "Seizures are a known adverse effect of clozapine therapy." | ( Park, SH; Williams, AM, 2015) |
| "Seizures are a known co-occurring symptom of Alzheimer's disease, and they can accelerate cognitive and neuropathological dysfunction." | ( Harrison, FE; Kang, JQ; Kennard, JA; Warner, TA, 2015) |
| "Seizures are accompanied by cardiovascular changes that are a major cause of sudden unexpected death in epilepsy (SUDEP)." | ( Bhandare, AM; Farnham, MM; Mohammed, S; Pilowsky, PM, 2015) |
| "SSRI-induced seizures are rare and are more likely to be associated with larger doses and severe symptoms such as those present in serotonin syndrome." | ( McKean, J; Mokszycki, R; Watts, H, 2015) |
| "Postoperative seizures are more common in the first month after cranial surgery." | ( Boza, FM; Gumà I Padró, J; Peralta Muñoz, S; Taberner Bonastre, MT, 2015) |
| "In epilepsy, seizures are generated by abnormal synchronous activity in neurons." | ( Alberto, MV; Anne, S; Laura, MC; Xóchitl, FP, 2015) |
| "Seizures are common during the neonatal period, often due to hypoxic-ischemic encephalopathy and may contribute to acute brain injury and the subsequent development of cognitive deficits and childhood epilepsy." | ( Boylan, GB; Dunleavy, M; Henshall, DC; Jimenez-Mateos, EM; Rodriguez-Alvarez, N; Waddington, JL, 2015) |
| "In newborns, seizures are most commonly associated with hypoxic-ischemic encephalopathy (HIE)." | ( Raol, YH; Sampath, D; Shmueli, D; White, AM, 2015) |
| "Neonatal seizures are commonly associated with hypoxic-ischemic encephalopathy." | ( Johnston, MV; Kadam, SD; Kang, SK, 2015) |
| "Febrile seizures are the most common type of convulsive events in children." | ( Blumberg, MS; Kaila, K; Pospelov, AS; Puskarjov, M; Yukin, AY, 2016) |
| "Convulsion is one of the most common problems in children and hypocalcemia is one the most frequent etiological items in children's convulsion." | ( Haghi Ashtiani, MT; Keihani Douste, Z; Shariat, M; Tehrani, F, 2015) |
| "Epileptic seizures are generally unpredictable and arise spontaneously." | ( Beniczky, S; Caciagli, L; Koepp, MJ; Lehnertz, K; Pressler, RM, 2016) |
| "Myoclonic seizures are a hallmark of feline audiogenic seizures (FARS)." | ( Bessant, C; Garosi, L; Harvey, RJ; Lowrie, M; Sparkes, A; Thomson, S, 2017) |
| "Neonatal seizures are associated with long term disabilities including epilepsy and cognitive deficits." | ( Benke, TA; Bernard, PB; Castano, AM; O'Leary, H, 2016) |
| "Generally, seizures are accompanied by changes in brain function leading to uncontrolled nerve activity causing high blood pressure, rapid heart rate, and abnormal heart rhythm." | ( Bhandare, AM; Farnham, MM; Kapoor, K; Pilowsky, PM, 2016) |
| "Seizures are accompanied by an exacerbated activation of cerebral ion channels." | ( Aldana, BI; Reed, RC; Sitges, M, 2016) |
| "The odds ratio of seizure is 5." | ( Lin, Z; Xiaoyi, Z, 2016) |
| "Seizures are common following perinatal asphyxia and may exacerbate secondary neuronal injury." | ( Berg, M; Soll, R; Young, L, 2016) |
| "Seizures are common complications for patients with brain tumors." | ( Nasr, ZG; Paravattil, B; Wilby, KJ, 2016) |
| "Post-stroke seizures are considered as a major cause of epilepsy in adults." | ( Lei, Z; Liang, Y; Xu, ZC; Zhang, H, 2016) |
| "Epileptic seizures are network-level phenomena." | ( Casteels, C; Cleeren, E; Goffin, K; Janssen, P; Premereur, E; Van Paesschen, W, 2016) |
| "Seizures are bursts of excessive synchronized neuronal activity, suggesting that mechanisms controlling brain excitability are compromised." | ( Bassell, GJ; Danielson, SW; Danzer, SC; Engel, T; Gross, C; Henshall, DC; Jimenez-Mateos, EM; Pun, RYK; Rowley, S; Schroeder, LM; Thomas, KT; Tiwari, D; Xing, L; Yao, X, 2016) |
| "Convulsive seizures are due to abnormal synchronous and repetitive neuronal discharges in the central nervous system (CNS)." | ( Asadi, S; Fereidoni, M; Kordi Jaz, E; Moghimi, A; Roohbakhsh, A; Shamsizadeh, A, 2017) |
| "Neonatal seizures are a common problem in the neonatal intensive care unit and are frequently treated with antiepileptic drugs." | ( Ahmad, KA; Ahmad, SF; Bennett, MM; Clark, RH; Desai, SJ; Ng, YT; Tolia, VN, 2017) |
| "These seizures are caused by sudden which may vary from a brief lapse of attention or muscle jerks, to severe and prolonged convulsions." | ( Jain, N; Jaiswal, J; Pathak, A; Singour, PK, 2018) |
| "Seizures are more common in patients with early onset or progressive forms of the disease and prognosticate rapid progression to disability and death." | ( Binder, DK; Hasselmann, JPC; Khalaj, AJ; Lapato, AS; Szu, JI; Tiwari-Woodruff, SK, 2017) |
| "A seizure is a sustained increase in brain electrical activity that can result in loss of consciousness and injury." | ( Beattie, CE; Berberoglu, MA; Duy, PQ; Hall, CW, 2017) |
| "Postoperative seizure is a common complication of cranioplasty, especially in patients with preoperative or postoperative abnormal EEG with spikes or sharp waves." | ( Ding, P; Liang, S; Wu, Y; Zhang, J; Zhang, S, 2017) |
| "Seizures are very common in children." | ( Julliand, S; Moretti, R; Rinaldi, VE; Titomanlio, L, 2019) |
| "In conclusion, seizures are generally the most common complication by a spectrum of seizure types, and sometimes cause symptomatic epilepsy." | ( Arslan, M; Güngör, S; Kılıç, B; Selimoğlu, MA; Yılmaz, S, 2017) |
| "Posttraumatic seizures are a medical problem affecting patients with traumatic brain injury." | ( Cao, Y; Liao, Z; Lu, XM; Mountney, A; Shear, DA; Tortella, FC, 2017) |
| "Seizure is the most common presentation of neurological disorder in the pediatric emergency care setting." | ( Demir, E; Gucuyener, K; Gurkas, E; Havali, C, 2019) |
| "Seizures are epileptic manifestations that are intrinsically modulated through different neurotransmitters and receptor systems." | ( Arzhang, A; Elahdadi Salmani, M; Goudarzi, I; Lashkarbolouki, T, 2017) |
| "Seizures are a common early presentation in infants with tuberous sclerosis complex (TSC) and can be preceded by electrographic changes on electroencephalography (EEG) before clinical seizure onset." | ( Jan, S; McCoy, B; Whitney, R; Zak, M, 2017) |
| "LGS type of seizures is epilepsy which is due to abnormal vibrations occurring in seizures." | ( Natchimuthu, V; Ramalingam, M; Ravi, S; Thomas, S, 2017) |
| "Neonatal seizures are the most common clinical manifestation of Central Nervous System (CNS) dysfunction and are associated with various neurological sequelae." | ( Agrawal, A; Banergee, A, 2017) |
| "Seizures are the commonest manifestation of brain parenchymal cysticercosis." | ( Sharma, R; Singh, G, 2017) |
| "Seizures are typically not responsive to conventional antiepileptic drugs, but they cease after parental pyridoxine administration." | ( Corsello, G; Falsaperla, R, 2017) |
| "Epileptic seizures are rare in nonalcoholic WE." | ( Chen, H; Chen, X; Hong, H; Li, X; Shang, W; Tang, S, 2017) |
| "Seizures are rare manifestation of thalamic disorder." | ( Brohi, H; Kumar, R; Mughul, A, 2017) |
| "History of seizure is an important risk factor for seizure occurrence in patients with mCRPC, particularly in those with a history of anticonvulsant use." | ( Bonafede, M; Dharmani, C; Krivoshik, A, 2017) |
| "Seizure is a serious complication of stroke, indicating poor prognosis." | ( An, XF; Liu, XJ; Yang, GS; Yu, D; Zhang, YJ; Zhou, XY, 2017) |
| "Seizures are common in infants with HIE undergoing TH and may worsen outcome." | ( Aronowitz, E; Hutton, A; Krishna, S; Moore, H; Vannucci, SJ, 2018) |
| "Epileptic seizures are short episodes of abnormal brain electrical activity." | ( Choi, BY; Choi, HC; Hong, DK; Jeong, JH; Kho, AR; Lee, SH; Lee, SY; Song, HK; Suh, SW, 2017) |
| "The risk of seizure is increased following brain surgery such as cranioplasty." | ( Liu, Y; Wang, Z; Zhang, B; Zhang, Z, 2018) |
| "Seizures are the most common neurological complication in neonatal intensive care units." | ( Lancaster, S; Manganas, LN; McHugh, DC, 2018) |
| "Epileptic seizures are refractory to treatment in approximately one-third of patients despite the recent introduction of many newer antiepileptic drugs (AEDs)." | ( Dash, A; Desudchit, T; Leung, H; Lim, KS; Tiamkao, S; Tsai, JJ; Wu, T, 2018) |
| "Incidence of seizure is similar in patients with mCRPC and similar seizure risk factors with or without enzalutamide exposure." | ( Carles, J; Clark, W; George, D; Krivoshik, A; Park, JW; Slovin, S; Wang, F, 2018) |
| "Neonatal seizures are treated with phenobarbital and prolonged treatment does not prevent postneonatal epilepsy." | ( Beatty, CW; Gust, J; Hamiwka, L; Natarajan, N, 2018) |
| "Currently, an epileptic seizure is considered to involve a temporary network that exists for a finite period of time." | ( Bragin, A; Engel, J; Kriukova, K; Li, L, 2018) |
| "Seizures are important complications following a subarachnoid hemorrhage (SAH)." | ( Buxton, J; Mahmoud, SH, 2017) |
| "An early onset of seizures is common in MLC." | ( Boschert, U; Brouwers, E; Bugiani, M; Dubey, M; Hamilton, EMC; Koch, H; Kole, MHP; Mansvelder, HD; Min, R; Stiedl, O; van der Knaap, MS; Wykes, RC, 2018) |
| "Seizures are present in over 90% of infants and children with Wolf-Hirschhorn syndrome (WHS)." | ( Battaglia, A; Carey, JC; Ho, KS; Lortz, A; Markham, LM; Newcomb, T; Olson, LM; Sheng, X; Twede, H; Wassman, ER; Weng, C, 2018) |
| "Catamenial seizures are believed to be a neurosteroid withdrawal symptom, and it was hypothesized that exogenous administration of progesterone to maintain its levels high during luteal phase will treat catamenial seizures." | ( Joshi, S; Kapur, J, 2019) |
| "Seizures are common in newborns after asphyxia at birth and are often refractory to anti-seizure agents." | ( Bennet, L; Davidson, JO; Draghi, V; Galinsky, R; Gunn, AJ; Lear, CA; Unsworth, CP, 2018) |
| "Seizures are controllable with antiepileptic drugs (AEDs) in about 70% of epilepsy patients, however, there remains about 30% of patients inadequately medicated with these AEDs, who need a satisfactory control of their seizure attacks." | ( Kondrat-Wróbel, MW; Łuszczki, JJ, 2018) |
| "Seizure is one of the important symptoms of tramadol poisoning, but its causes are still unknown." | ( Ahmadimanesh, M; Ahsani Nasab, S; Ghazi-Khansari, M; Rouini, MR; Shadnia, S; Sheikholeslami, B, 2018) |
| "The pathogenesis of epileptic seizures is not satisfactorily explored, and hence more effective anti-convulsive therapies are indispensable." | ( El-Azab, MF; Moustafa, YM; Tawfik, KM, 2018) |
| "Such early-life seizures are associated with language deficits and autism that can result from aberrant development of the auditory cortex." | ( Hensch, TK; Jensen, FE; Lippman-Bell, JJ; Sun, H; Takesian, AE; Wang, TT, 2018) |
| "Persistent seizures are associated with physical injury, reduced quality of life, and psychosocial impairment." | ( De Rosendo, J; Howard, D; Patel, V; Tremblay, G; Tsong, W, 2018) |
| "Neonatal seizures are harmful to the developing brain and are associated with mortality and long-term neurological comorbidities." | ( Carter, BM; Kadam, SD; Kharod, SC, 2018) |
| "Neonatal seizures are frequent in neonatal intensive care and the most common cause is perinatal asphyxia." | ( Cools, F; Demeulemeester, V; Lefevere, J; Van Hautem, H, 2018) |
| "Epileptic seizures are associated with increased astrocytic Ca2+ signaling, but the fine spatiotemporal kinetics of the ictal astrocyte-neuron interplay remains elusive." | ( Åbjørsbråten, KS; Enger, R; Heuser, K; Jensen, V; Nagelhus, EA; Nome, CG; Pettersen, KH; Sprengel, R; Tang, W; Taubøll, E, 2018) |
| "Seizures are sustained neuronal hyperexcitability in brain that result in loss of consciousness and injury." | ( Han, L; He, Q; Ji, X; Jin, M; Liu, K; Sheng, W, 2018) |
| "Epileptic seizure is the result of uncontrollable neural excitation in the brain." | ( Bayraktutan, OF; Ceylan, M; Laloglu, E; Yalcin, A, 2018) |
| "Seizures are common in term infants with hypoxic-ischemic encephalopathy (HIE) undergoing therapeutic hypothermia." | ( Chanlaw, T; Cho, A; Garg, M; Hussain, SA; Rao, LM; Sankar, R; Zaki, T, 2018) |
| "Seizures are easily controlled by AEDs." | ( Kalita, J; Kumar, V; Misra, UK; Parashar, V, 2019) |
| "Symptoms during seizure are very important to diagnose." | ( Zhou, W; Zhu, Q, 2018) |
| "Seizures are commonly thought to occur in a spontaneous, unpredictable manner." | ( Hassan, I; Hrazdil, CT; Randhawa, J, 2019) |
| "Seizures are a feature not only of the many forms of epilepsy, but also of global metabolic diseases such as mitochondrial encephalomyopathy (ME) and glycolytic enzymopathy (GE)." | ( Barile, ZJ; Fogle, KJ; Gutierrez, AC; Hertzler, JI; McCardell, CS; Novak, MO; Palladino, MJ; Satterfield, SL; Shon, JH; Smith, AR, 2019) |
| "Epileptic seizures are frequent in patients with glioblastoma, and anticonvulsive treatment is often necessary." | ( Bergner, C; Hörnschemeyer, J; Kirschstein, T; Köhling, R; Krause, BJ; Lange, F; Linnebacher, M; Mullins, CS; Porath, K; Weßlau, K, 2019) |
| "Febrile seizure is a common neurological disorder observed in neonates." | ( Moghimi, A; Roohbakhsh, A; Zandi, N; Zaniani, NR, 2019) |
| "Neonatal seizures are different from adult seizures, and many antiepileptic drugs that are effective in adults often fail to treat neonates." | ( Bai, Y; Chen, G; Dong, F; Feng, M; Huo, Q; Li, ST; Long, C; Lüscher, B; Ren, L; Wang, GL; Wang, Y; Wu, G; Wu, Z, 2019) |
| "However, seizures are not typical and the majority of them were seizure-free." | ( Goji, A; Imoto, I; Ito, H; Kagami, S; Kohmoto, T; Mori, K; Mori, T; Toda, Y, 2019) |
| "The prevalence of seizures is reported to be 1." | ( Basha, MM; Bernitsas, E; Marawar, R; Sriwastava, S; Yarraguntla, K; Zutshi, D, 2019) |
| "Acute seizures are common in pediatric cerebral malaria (CM), but usual care with phenobarbital risks respiratory suppression." | ( Abdel Baki, SG; Birbeck, GL; Capparelli, EV; Dzinjalamala, FK; Gardiner, JC; Herman, ST; Mallewa, M; Postels, DG; Seydel, KB; Taylor, TE; Toto, NM, 2019) |
| "Unlike in children, seizures are unusual in adult patients with eucalyptus oil poisoning." | ( George, GR; Ittyachen, AM; Joy, Y; Radhakrishnan, M, 2019) |
| "Seizures are uncommon among younger children with exploratory ingestions." | ( Gosen, J; Levine, M; Offerman, S; Thomas, SH, 2020) |
| "Epileptic seizures are frequent in patients with glioma, and anticonvulsive treatment is often indicated." | ( Kirschstein, T; Köhling, R; Krause, BJ; Lange, F; Mayer, J; Porath, K; Resch, T, 2020) |
| "Seizures are induced when subjects are exposed to severe hypoxia." | ( Fukushi, I; Horiuchi, J; Kurita, Y; Mori, Y; Okada, Y; Okazaki, S; Pokorski, M; Takeda, K; Uchiyama, M; Yokota, S, 2020) |
| "Drug-resistant seizures are life-threatening and contribute to sustained hospitalization." | ( Capra, S; Narayan, SW; Parratt, K; Patanwala, AE, 2020) |
| "Controlling seizures is essential during GBM treatment because they are often present and closely associated with the quality of life of GBM patients." | ( Chang, MJ; Min, KL; Ryu, JY, 2019) |
| "Paradoxical seizure is an unusual reaction of seizure aggravation or change in its pattern due to antiepileptics." | ( Radhakrishnan, A; Sudarsan, P; Suresh, A; Varghese, R, 2021) |
| "Epileptic seizures are characterized by synchronized discharges of neurons, leading to the activation of inflammatory responses that in turn contributes to seizure progression." | ( Ji, X; Jin, M; Liu, K; Sik, A; Wang, L; Zhang, B; Zhang, S, 2020) |
| "Neonatal seizures are difficult to diagnose and, when they are, tradition dictates first line treatment is phenobarbital." | ( Alix, JJP; Gossling, L; Hart, AR; Stavroulakis, T, 2020) |
| "Seizures are a combination of electrical and behavioral events that can induce biochemical, molecular, and anatomic changes." | ( Adem, A; Alachkar, A; Frank, A; Ojha, SK; Sadek, B; Sadeq, A; Stark, H, 2020) |
| "Seizures are a morbid complication of intracerebral hemorrhage (ICH) and increase the risk for herniation, status epilepticus, and worse patient outcomes." | ( Naidech, AM; Pinto, D; Prabhakaran, S; Tipton, E, 2020) |
| "Seizures are known to trigger a neuroinflammatory response to promote neuronal damage and increase the risk of epilepsy." | ( Fox, P; Koh, S; Mithal, DS; Sanchez, RM; Somogyi, JR; Vien, AC, 2020) |
| "Focal-onset or partial seizures are localized to a specific brain area or areas of the cerebral hemisphere." | ( Dhir, A, 2020) |
| "As seizures are precipitated in children with GA-I and the mechanisms underlying this disorder are not well established, we decided to investigate the role of nitric oxide (NO) in GA-induced convulsive behaviour in pup rats." | ( Bortolatto, CF; Brüning, CA; Magni, DV; Nogueira, CW; Nonemacher, NT; Quines, CB; Rosa, SG, 2020) |
| "Acute symptomatic seizures are possible in patients with COVID-19 disease." | ( Bhimraj, A; George, P; Hantus, S; Hepburn, M; Mullaguri, N; Newey, CR; Punia, V, 2021) |
| "Seizure is a common acute and severe disease in infants and children." | ( Hu, QP; Huang, XY; Peng, F; Wu, C; Yang, H, 2020) |
| "As seizures are commonly associated with autonomic manifestations, we believe that biomarkers for diseases affecting autonomic functions such as epilepsy can be found in vagus nerve signals." | ( Cury, J; Delbeke, J; Doguet, P; Hermans, E; Nielsen, TN; Nonclercq, A; Sevcencu, C; Smets, H; Stumpp, L; Tahry, RE; Vespa, S, 2020) |
| "Various types of generalized seizures are most prevalent, with most common types are myoclonic and atypical absence." | ( Samanta, D, 2021) |
| "Neonatal seizures are frequently encountered in the neonatal intensive care unit and may be associated with serious long-term neurological sequelae." | ( Darwich, M; Hanneyan, S; Hnaini, M; Jaafar, F; Koleilat, N; Maalouf, FI; Mikati, IE; Nabout, R; Obeid, M; Rahal, S; Shbarou, RM, 2020) |
| "A seizure is an uncontrolled electrical activity in the brain that can cause different levels of behavior, emotion, and consciousness." | ( Ahn, JH; Ahn, SH; Bae, MA; Chae, JS; Cho, JH; Hwang, KS; Jang, IS; Joo, J; Kan, H; Kim, CH; Kim, SS; Shin, DS; Shin, J; Yang, JY, 2020) |
| "Neonatal seizures are one of the most common comorbidities of neonatal encephalopathy, with seizures aggravating acute injury and clinical outcomes." | ( Engel, T; Menéndez Méndez, A; Smith, J, 2020) |
| "First unprovoked seizures are not influenced by the lunar cycle." | ( Boston, R; Lawn, N; Seneviratne, U; Wang, S, 2022) |
| "Epileptic seizures are automatic, excessive, and synchronized neuronal activities originating from many brain regions especially the amygdala, the allocortices and neocortices." | ( Chou, P; Hsueh, SW; Kuo, CC; Wang, GH; Yang, YC, 2021) |
| "Neonatal seizures are the most frequent type of neurological emergency in newborn infants, often being a consequence of prolonged perinatal asphyxia." | ( Ala-Kurikka, T; Gailus, B; Hampel, P; Johne, M; Kaila, K; Löscher, W; Römermann, K; Theilmann, W, 2021) |
| "Seizures are a threat to the host brain and body and can even cause death in epileptic children." | ( Eor, JY; Kim, SH; Kwak, MJ; Son, YJ; Tan, PL, 2021) |
| "Epileptic seizures are considered to be a brain network dysfunction, and chronic recurrent seizures can cause severe brain damage." | ( Chen, C; Li, F; Liang, Y; Xu, P; Yao, D; Yu, L, 2020) |
| "Epileptic seizures are characterized by imbalanced inhibition-excitation cycle that triggers biochemical alterations responsible for jeopardized neuronal integrity." | ( Mishra, P; Rajput, SK; Sinha, JK, 2021) |
| "Since seizures are highly unlikely to be detected in a routine scalp EEG, the primary diagnosis depends heavily on the visual evaluation of Interictal Epileptiform Discharges (IEDs)." | ( Cash, SS; Chaudhari, R; Dauwels, J; Jing, J; Karia, S; Peh, WY; Rathakrishnan, R; Saini, V; Shah, N; Srivastava, R; Tan, YL; Thangavel, P; Thomas, J; Westover, B; Yuvaraj, R, 2021) |
| "Sevoflurane-induced seizures are most often caused by high concentrations of sevoflurane during anesthesia induction." | ( Du, L; Zhang, L; Zheng, J, 2021) |
| "Epileptic seizures are the most common neurological diseases that change the function of neurovascular unit at molecular levels accompanied by activation of a wide variety of neurodegenerative cascades." | ( Darabi, S; Faghihi, N; Mohammadi, MT; Sarahian, N, 2021) |
| "Seizures are a common manifestation of toxic exposures requiring immediate and possibly ongoing management." | ( Alunday, RL; Fletcher, ML; Nash, J; Sarangarm, P; Seifert, SA; Smolinske, SC; Warrick, BJ, 2021) |
| "Seizures are physically burdensome and emotionally distressing for patients, families, caregivers, and clinicians." | ( Besbris, JM; Daly, FN; Jones, CA; Kramer, NM; Mehta, AK; Sharma, A; Singhal, D, 2021) |
| "First seizures are always challenging for physicians." | ( Carrizosa-Moog, J; Jiménez-Villegas, MJ; Lozano-García, L, 2021) |
| "Seizures are common in patients with gliomas; however, the mechanisms of epileptogenesis in gliomas have not been fully understood." | ( Abe, M; Hirose, Y; Inamasu, J; Kumon, M; Kuwahara, K; Murayama, K; Nakae, S; Ohba, S; Sasaki, H; Yamada, S, 2021) |
| "Myoclonic seizures are the most common seizure type, and 56." | ( Cao, D; Fahlke, C; Guzman, RE; He, H; Peng, J; Sierra-Marquez, J; Stauber, T; Yin, F, 2021) |
| "Neonatal seizures are significant cause of neonatal mortality and morbidity." | ( Aggarwal, A; Banerjee, BD; Batra, P; Famra, K, 2022) |
| "Epileptic seizures are core symptoms in focal cortical dysplasia (FCD), a disease that often develops in infancy." | ( Akiyama, T; Inoue, Y; Kada, A; Kato, M; Nakagawa, E; Saito, AM; Shiraishi, H; Takahashi, Y; Tohyama, J, 2021) |
| "Seizures are common in neonates recovering from birth asphyxia but there is general consensus that current pharmacotherapy is suboptimal and that novel antiseizure drugs are needed." | ( Ala-Kurikka, T; Kaila, K; Kurki, S; Pospelov, AS; Voipio, J, 2021) |
| "The risk of seizures is 10-fold higher in patients with Alzheimer's disease than the general population, yet the mechanisms underlying this susceptibility and the effects of these seizures are poorly understood." | ( Barbour, AJ; Eberwine, G; Gourmaud, S; Irwin, DJ; Jensen, FE; O'Brien, WT; Roberts, N; Stewart, DA; Talos, DM; Vassar, R, 2022) |
| "Seizures are common in newborn infants with hypoxic-ischemic encephalopathy and are highly associated with adverse neurodevelopmental outcomes." | ( Bennet, L; Cho, KHT; Davidson, JO; Drury, PP; Gunn, AJ; Lear, CA; McDouall, A; Zhou, KQ, 2021) |
| "Absence seizures are associated with generalised synchronous 2." | ( Leitch, B; Lyons, NMA; Panthi, S, 2021) |
| "Seizures are the outward manifestation of abnormally excessive or synchronous brain activity." | ( Abas, F; Choo, BKM; Faudzi, SMM; Kundap, UP; Samarut, É; Shaikh, MF, 2021) |
| "Reflex seizures are consistently evoked by a specific afferent stimulus or by patient activity." | ( Parente, E; Rebessi, E; Riva, A; Romeo, A; Striano, P; Viri, M, 2022) |
| "Epileptic seizures are increasingly recognized as part of the clinical phenotype of patients with Alzheimer's disease (AD)." | ( Larner, AJ; Marson, AG, 2022) |
| "These seizures are paroxysmal events that result from abnormal neuronal discharges and are categorized into various types based on the clinical manifestations and localization." | ( Karthick, PA; Mathew, J; Ramakrishnan Manuskandan, S; Sivakumaran, N, 2021) |
| "Seizures are common in NBIA, particularly in PLAN and BPAN." | ( Emamikhah, M; Fasano, A; Mohammadzadeh, N; Rohani, M; Saiyarsarai, P; Schneider, SA, 2023) |
| "NAC effects on absence seizures are still not uncovered, and considering its clinical use as a mucolytic in patients with lung diseases, people with epilepsy are also likely to be exposed to the drug." | ( Citraro, R; Constanti, A; De Caro, C; De Sarro, G; Guarnieri, L; Leo, A; Nicoletti, F; Russo, E; Tallarico, M; Zito, MC, 2022) |
| "Pediatric seizures are a common reason for emergency department visits." | ( Case, SD; Tsao, HS, 2022) |
| "Seizures are a disorder caused by structural brain lesions, life-threatening metabolic derangements, or drug toxicity." | ( Andrade, AR; Barbas, LAL; Ferreira, LO; Hamoy, AO; Hamoy, M; Jóia de Mello, V; Leitão, DS; Lopes, DCF; Martins, MFC; Medeiros, NCL; Muto, NA; Santos, VC, 2022) |
| "Focal seizures are associated with various co-morbidities." | ( Bhattacharyya, A; Mahajan, SS; Medhi, B; Niraj, N; Prakash, A; Sarma, P, 2022) |
| "Epileptic seizures are associated with the overproduction of free radicals in the brain leading to neuronal cell death." | ( Dehdashtian, E; Hosseinzadeh, A; Jafari-Sabet, M; Mehrzadi, S, 2022) |
| "Seizures are a common complication that leads to neurological deficits and affects outcomes after aneurysmal subarachnoid haemorrhage (aSAH)." | ( Chen, Y; Fang, M; Hu, X; Li, Y; Pang, B; Sun, B; Wu, H; Wu, P; Wu, Q; Xie, Z; Xu, S; You, C; Zhang, J; Zheng, N, 2022) |
| "Neonatal seizures are one of the most challenging problems for experts across the globe." | ( Deshmukh, L; Joshi, A; Londhe, A; Susnerwala, S, 2022) |
| "Seizure is a rare side effect of enzalutamide." | ( Demir, O; Demirag, G, 2023) |
| "Seizures are the main neurological emergency during the neonatal period and are mostly acute and focal." | ( Bedetti, L; Berardi, A; Casa Muttini, ED; Cavalleri, F; Ferrari, F; Guidotti, I; Lugli, L; Ori, L; Pugliese, M; Roversi, MF; Stefanelli, F, 2022) |
| "Seizures are more common in the neonatal period than at any other stage of life." | ( Allison, BJ; Bennet, L; Boyd, BJ; Castillo-Melendez, M; Fahey, MC; Hirst, JJ; Hunt, RW; Jenkin, G; Malhotra, A; McDonald, C; Mihelakis, J; Miller, SL; Nitsos, I; Pham, Y; Sutherland, AE; Walker, DW; Wong, F; Yawno, T, 2022) |
| "Seizures are a common clinical manifestation in neuropsychiatric lupus, and our work identifies anti-BC autoantibody activity as a mechanistic cause." | ( Berardi, V; Ginzler, EM; Hanly, JG; Muslimov, IA; Stephenson, S; Tiedge, H, 2022) |
| "Seizures are a frequent and diagnostically relevant symptom of ab + AE." | ( Angstwurm, K; Bergh, FT; Bien, CG; Bogarin, Y; Doppler, K; Finke, A; Geis, C; Gerner, ST; Handreka, R; Häusler, M; Hellwig, K; Kaaden, T; Kaufmann, M; Kellinghaus, C; Koertvelyessy, P; Kraft, A; Kunze, A; Lewerenz, J; Leypoldt, F; Madlener, M; Malter, M; Melzer, N; Menge, T; Mues, S; Paliantonis, A; Prüss, H; Rauer, S; Reimann, G; Ringelstein, M; Rostásy, K; Schirotzek, I; Schwabe, J; Sokolowski, P; Suesse, M; Sühs, KW; Surges, R; Tauber, SC; Thaler, F; Urbanek, C; von Podewils, F; Wandinger, KP; Wildemann, B; Zettl, U, 2022) |
| "The seizures are generally resistant to traditional antiepileptic drugs and show a dramatic response to high-dose pyridoxine." | ( Çavdartepe, BE; İpek, R; Kor, D; Okuyaz, Ç, 2022) |
| "A seizure is a significant in-flight medical emergency event." | ( Asadi-Pooya, AA; Hosseini, SA, 2022) |
| "Seizure is paroxysmal abnormal electrical discharges in the cerebral cortex." | ( Amini-Khoei, H; Bijad, E; Dehkordi, HT; Korrani, MS; Saghaei, E, 2023) |
| "Absence seizures are hyperexcitations within the cortico-thalamocortical (CTC) network, however the underlying causative mechanisms at the cellular and molecular level are still being elucidated and appear to be multifactorial." | ( Adotevi, NK; Hassan, M; Leitch, B, 2022) |
| "Seizures are a complex of transient signs and symptoms resulting from abnormal, simultaneous, and excessive activity of a population of neurons, and they can be both a cause and a consequence of oxidative stress." | ( López-Meraz, ML; Pérez-Severiano, F; Ramos-Riera, KP, 2023) |
| "Seizures are suspected to be side effects of antipsychotics." | ( Efthimiou, O; Leucht, S; Reichelt, L; Schneider-Thoma, J, 2023) |
| "A post stroke seizure is a period of neurological dysfunction caused by abnormal neuronal activity." | ( Lidetu, T; Zewdu, D, 2023) |
| "Seizures are common in palliative care patients and its control is essential in the management of these patients as it helps to reduce suffering at the end of life." | ( Diaz-Forero, AF; Estrada, J; Gaviria-Carrillo, M; Mora-Muñoz, L; Rodríguez, JH; Torres-Ballesteros, V; Vargas-Osorio, J; Vélez Van Meerbeke, A, 2023) |
| "This motor seizure is irrelevant to the therapeutic action of the treatment." | ( Andrade, C, 2023) |
| "Seizures are considered to be the most common symptom encountered in emergency- rushed tramadol-poisoned patients; accounting for 8% of the drug-induced seizure cases." | ( El-Bassyouni, GT; Elgohary, R; ElShebiney, SA; Hamzawy, EMA; Kenawy, SH, 2023) |
| "Seizures are a frequent pathophysiological feature of malignant glioma." | ( Aiba, I; Cervantes, A; Cocito, C; Curry, RN; Deneen, B; Gavvala, J; Greenfield, JP; Huang-Hobbs, E; Jalali, A; Ko, Y; Lozzi, B; McDonald, MF; Meyer, J; Mohila, C; Noebels, J; Rao, G; Rosenbaum, A; Serin Harmanci, A, 2023) |
| "Seizures are life-threatening complications of neuropsychiatric systemic lupus erythematosus (NPSLE) and are often associated with poor outcomes." | ( Jiang, W; Shi, Y; Wu, J; Zhang, J; Zhang, L, 2023) |
| "Seizures are common neurological emergencies in the elderly that are frequently provoked." | ( Alattiya, MK; Hammamy, RA; Joudeh, AI, 2023) |
| "Seizures are among the most common clinical signs in people with glioblastoma." | ( Cole, AJ; Dietrich, J; Sokolov, E, 2023) |
| "Neonatal seizures are severe pathologies which may result in long-term neurological consequences." | ( Gataulina, E; Gerasimova, E; Khalilov, I; Kurmashova, E; Sitdikova, GF; Yakovlev, AV, 2023) |
| "Urgent seizures are a medical emergency for which new therapies are still needed." | ( Asensio, M; Campos, D; Castillo, A; Chavarria, B; Escalza, I; Falip, M; Fernández-Cabrera, A; Garcés, M; García-Morales, I; Gifreu, A; Giménez, J; Guillén, V; Hampel, K; Hernández Pérez, G; Juiz-Fernández, Á; Martínez, AB; Massot, M; Montoya, J; Parejo-Carbonell, B; Rocamora, R; Rodriguez-Osorio, X; Rubio-Nazábal, E; Ruiz-Giménez, J; Santamarina, E; Sayas, D; Villanueva, V, 2023) |
| "Seizures are a common neurological disorder that affects people of all ages." | ( Fathi, E; Panahi, Y; Shafiian, MA, 2023) |
| "Seizures are common in neonates, but there is substantial management variability." | ( Abend, NS; Auvin, S; Boylan, G; Brigo, F; Cilio, MR; De Vries, LS; Elia, M; Espeche, A; Hahn, CD; Hartmann, H; Inder, T; Jette, N; Kakooza-Mwesige, A; Mader, S; Mizrahi, EM; Moshé, SL; Nagarajan, L; Noyman, I; Nunes, ML; Pressler, RM; Samia, P; Shany, E; Shellhaas, RA; Subota, A; Triki, CC; Tsuchida, T; Vinayan, KP; Wilmshurst, JM; Yozawitz, EG, 2023) |
| "Classically, seizures are assumed to occur at random." | ( Anderson, C; Bagshaw, AP; Cook, MJ; D'Souza, W; Lightman, SL; Marinelli, I; Seneviratne, U; Terry, JR; Walker, JJ; Woldman, W, 2023) |
| "Seizures are associated with a decrease in γ-aminobutyric type A acid receptors (GABAaRs) on the neuronal surface, which may be regulated by enhanced internalization of GABAaRs." | ( Huang, H; Li, S; Lu, Y; Ma, M; Sun, L; Wei, X; Wu, Y; Ye, L, 2023) |
| Excerpt | Reference |
|---|
| "The pattern of daily convulsions evoked by cocaine MCD changed from multiple episodes of intermittent tonic-clonic convulsions, which occurred during the earlier stage (1--2 months) of chronic treatment, to a single episode of sustained tonic-clonic convulsion." | ( Matsuzaki, M, 1978) |
| "The initial seizure was induced by the cortical suprafusion of PGE1 over the left visual cortex of PG transport inhibitor-pretreated rabbits." | ( Bito, LZ; Wallenstein, MC, 1979) |
| "Thiopental was administered for seizure control in 2 patients with uncontrollable seizures." | ( Cloyd, JC; Perrier, D; Wright, BD, 1979) |
| "Withdrawal seizures were evident on cessation of CZP administration." | ( Congdon, WC; DuCharme, LL; Levy, RH; Lockard, JS; Salonen, LD, 1979) |
| "The effect of each drug on seizures (tonic, tonic-clonic, clonic, myoclonic or myoclonic-atonic, atonic and atypical absences) during the first month of each treatment is discussed." | ( Lison, MP; Speciali, GG, 1977) |
| "Epilepsy-like convulsive seizures have been induced by cholera toxin administration into the rat amygdaloid complex." | ( Kakita, K; Kuriyama, K, 1979) |
| "Eight patients developed grand mal seizures during intravenous theophylline therapy." | ( Cohn, WM; Matthay, RA; Neff, TA; Sutton, FD; Weinberger, MM; Zwillich, CW, 1975) |
| "Twenty-seven children with uncontrolled seizures, predominantly akinetic and myoclonic, were treated with this drug." | ( Botsford, E; Freeman, JM; Vining, EP, 1979) |
| "Thirty children with simple febrile convulsions were treated with sodium valproate following their second convulsion." | ( Evans-Jones, LG; Groom, PJ; Kindley, AD; Williams, AJ, 1979) |
| "Metrizamide-induced seizures could be prevented by intramuscular preadministration of diazepam." | ( Davis, JP; Eldevik, OP; Gager, WE; Harris, GJ; Haughton, VM, 1979) |
| "The thresholds of twitch and clonic convulsion induced by intravenous infusion of pentylenetetrazol (PTZ) were measured in rats treated with 6-hydroxydopamine (6-OHDA)." | ( Fukuda, T; Oishi, R; Suenaga, N, 1979) |
| "Early treatment (convulsions less than or equal to 15 minutes) had effect in 96%, and late treatment (convulsions greater than 15 minutes) in 57% of cases." | ( Knudsen, FU, 1979) |
| "When the convulsions were protected by pretreatment with AOAA, the decreased GABA releases in both the conditions rose to or above the normal levels." | ( Asakura, T; Hoshino, M; Matsuda, M, 1979) |
| "A 4-year-old girl who developed convulsions after an accidental ingestion of excessive dosage (50 mg/kg) of nalidixic acid, while treated with the drug (50 mg/kg/day) over 30 days for a urinary tract infection, was reported." | ( Jo, M; Shinoda, M; Tachi, N, 1979) |
| "Clonic convulsions after intracranial administration of NMGI in dogs occurred when NMGI was given into the parenchyma but not when given into the ventricle." | ( Wakabayashi, K, 1977) |
| "When seizures developed, intravenous phenytoin sodium therapy was begun." | ( Bivins, BA; Blouin, R; Bustrack, J; Griffen, WO; Rapp, RP, 1978) |
| "A Tanzanian man with a known seizure disorder was admitted to hospital for treatment of schistosomiasis mansoni." | ( Keystone, JS, 1978) |
| "During the convulsions by TSC 16hr after the AOAA-pretreatment, the GABA content in synaptosomes was less than that from the group treated with AOAA alone, though its GABA level was higher than the normal level." | ( Abe, M, 1978) |
| "during epileptic seizures and after amphetamine-administration, protein leakage in the brain is more pronounced than in hypertension per se." | ( Johansson, BB; Lund, S, 1978) |
| "Before the onset of lignocaine-induced seizures in non-treated animals, the animals appeared to be drowsy." | ( Ausinsch, B; Malagodi, MH; Munson, ES, 1976) |
| "The effect of electrically induced convulsions was tested on the tolerance to hexobarbital after chronic barbital treatment in male rats." | ( Wahlström, G, 1976) |
| "When premidication is needed or when convulsions occur after Amipaque examinations, combined diazepam and phenobarbital therapy ought to be instituted in order to achieve the best control of epileptic reactions." | ( Brucher, JM; Gonsette, RE, 1977) |
| "If both minimal and maximal seizures are considered, the reserpine and combined treatment groups do not differ from one another, but do show a lower threshold as compared to ECS or control groups." | ( Blank, DL, 1976) |
| "The behavioral convulsions decrease in severity and then disappear after the long-term administration of delta9-tetrahydrocannabinol." | ( Consroe, P; Martin, P, 1976) |
| "Diazepam pretreatment raised the seizure threshold of bupivacaine." | ( Jenkins, LC; Robinson, WM, 1975) |
| "Attempts were made to control prolonged seizures with rapid intravenous administration of either diazepam or methohexitone in relatively small doses under electroencephalographic (EEG) monitoring." | ( Da Costa, AA; Pampiglione, G, 1975) |
| "Audiogenic seizures in DBA/2 mice have been studied after administration of drugs believed to act as dopamine agonists." | ( Anlezark, GM; Meldrum, BS, 1975) |
| "Hyperreflexia and periodic convulsions were controlled by initial intramuscular injections of 30 mg diazepam and 2 g methocarbamol, followed at 6-hour intervals with intramuscular injections of 30 mg diazepam each, for 2 additional treatments." | ( Peavy, GM, 1975) |
| "Successful treatment of partial complex seizures (and the epilepsies in general) is a process of management over time and involves several factors." | ( Booker, HE, 1975) |
| "That convulsion and other symptoms were due to cephaloridine was confirmed when the second intrathecal administration produced the same symptom." | ( Fujita, M; Nambu, H; Uehara, H; Yoshioka, H, 1975) |
| "On day 30 of life, seizure-treated rats had smaller brains (-56 mg, P less than ." | ( Wasterlain, CG, 1976) |
| "Diazepam pretreatment decreased the tonic seizure time following ECS in a dose-dependent manner." | ( Mathé, AA; Srinivasan, GR; Stenfors, C; Theodorsson, E, 1992) |
| "Tacrine elicited seizures and brain damage in 90% of the rats treated." | ( Bagetta, G; Iannone, M; Nisticò, G; Scorsa, AM, 1992) |
| "In mice, tonic convulsive seizure induced by intravenous administration of caffeine (adenosine A1, A2 receptors antagonist) was significantly potentiated by any one of L-PIA (adenosine A1 receptor agonist), NECA (adenosine A2 receptor agonist) and 2-ClAd (adenosine A1, A2 receptors agonist)." | ( Inano, S, 1992) |
| "Despite phenytoin administration, the seizure-like activity subsided only after discontinuing ganciclovir." | ( Barton, TL; Dever, LL; Roush, MK, 1992) |
| "Since clinical data indicate a seizure enhancing interaction between FQ and theophylline (THEO) we studied the influence of concurrent FQ-THEO administration in kindled rats." | ( Schwark, WS; Vancutsem, PM, 1992) |
| "Twenty-two patients had grand mal seizures during the administration periods." | ( Hori, M; Koizumi, J; Sasaki, M; Shiraishi, H; Suzuki, T, 1992) |
| "Withdrawal Seizure Prone (WSP) mice, genetically selected to develop severe handling-induced convulsions after withdrawal from chronic ethanol treatment, were exposed to ethanol vapor for 24 h." | ( Crabbe, JC, 1992) |
| "Withdrawal seizure prone (WSP) and withdrawal seizure resistant (WSR) mice were treated with 5 mg/kg lorazepam for 7 days via implanted osmotic mini pumps." | ( Allan, AM; Baier, LD; Zhang, X, 1992) |
| "administration to audiogenic seizure-susceptible DBA/2J mice." | ( Baron, BM; Harrison, BL; McDonald, IA; Meldrum, BS; Palfreyman, MG; Salituro, FG; Siegel, BW; Slone, AL; Turner, JP; White, HS, 1992) |
| "An eclamptic seizure occurring at 32+2 weeks of gestation was treated with magnesium sulfate." | ( Bleker, OP; Schutte, MF; Swartjes, JM, 1992) |
| "To evaluate the role of the acute seizures and associated hippocampal structural alterations in the development of this long-lasting susceptibility, rats that received intraventricular kainic acid were cotreated with phenobarbital (60 mg/kg, s." | ( Cavazos, J; Golarai, G; Sutula, T, 1992) |
| "One rat that developed seizures after CPX pretreatment needed a considerably reduced dose of thiopental to induce the silent-second." | ( Broholm, KA; Schliamser, SE; Wahlström, G, 1992) |
| "Spinal seizures in mice induced by handling following pretreatment with a subconvulsive dose of strychnine could be blocked by competitive N-methyl-D-aspartate (NMDA) receptor antagonists (D-, L-, DL-CPPene (CPPene = (E)-4-(3-phophonoprop-2-enyl)-piperazine-2-carboxylic acid), D-AP5 (D-2-amino-5-phophonovalerate)) and compounds acting at receptor-coupled modulatory sites (R-HA 966, ifenprodil)." | ( McAllister, KH, 1992) |
| "There were no convulsions subsequent to treatment, although the study was too small to assess anticonvulsant efficacy." | ( Chongsuphajaisiddhi, T; Holloway, P; Kuile, F; Maelankirri, L; Nosten, F; White, NJ, 1992) |
| "We compared the seizure frequency in the 3 months before and after methylphenidate with the seizure frequency during methylphenidate treatment, using the Wilcoxon signed-rank test." | ( Leary, JM; Manning, K; Phelan, AM; Whyte, J; Wroblewski, BA, 1992) |
| "Only 4 patients had greater seizure frequency during methylphenidate treatment, and 3 of these 4 were receiving tricyclic antidepressants." | ( Leary, JM; Manning, K; Phelan, AM; Whyte, J; Wroblewski, BA, 1992) |
| "Although electrical seizure activity in response to opioids such as fentanyl has been well described in animals, scalp electroencephalographic (EEG) recordings have failed to demonstrate epileptiform activity following narcotic administration in humans." | ( Bernardo, KL; Edwards, I; Modica, PA; Tempelhoff, R, 1992) |
| "EtOH withdrawal seizures of WSP mice were significantly increased by chronic and acute corticosterone treatment, whereas those of the WSR mice were unaffected." | ( Chu, HP; Crabbe, JC; Keith, LD; Roberts, AJ, 1991) |
| "Mice were observed for convulsions for 90 minutes after the administration of temafloxacin HCl (100 mg/kg orally [p." | ( Giardina, WJ, 1991) |
| "In fact, no convulsions were observed in the first week of treatment, but all the animals became sensitized to PTZ by the 12th week." | ( Biggio, G; Corda, MG; Giorgi, O; Longoni, B; Orlandi, M, 1990) |
| "In neonatally drug-treated rats, seizures during adulthood were found to occur with significantly higher incidence and severity." | ( Pierson, M; Swann, J, 1991) |
| "The incidences of both seizure and death for strychnine and death for picrotoxin were enhanced by treatment with GES, whereas the latency of pentetrazole-induced tonic extensor was prolonged." | ( Araki, H; Sano, M; Shimada, C; Tanaka, S, 1991) |
| "We report a patient with a seizure disorder on anticonvulsant therapy, who developed systemic reactive histiocytosis." | ( Galetta, SL; Hicks, DG; Oberholtzer, JC; Plock, G; Raps, EC; Stadtmauer, EA, 1991) |
| "In the present study, we examined the clonic seizure immediately preceding head-weaving behaviour elicited by 8-OH-DPAT (40 mg/kg, ip) administration in mice." | ( Fujii, E; Nomoto, T, 1991) |
| "The incidence of lidocaine-induced convulsions was decreased by treatments with alpha-MPT and disulfiram, while that of PTZ was increased by either treatment." | ( Dohi, T; Takada, K; Tanaka, S; Tsujimoto, A; Yoshimura, Y, 1991) |
| "AOAA also induced clonic convulsions in mice subjected to intracerebroventricular administration of the drug with a CD50 of 0." | ( Calderazzo-Filho, LS; Cavalheiro, EA; Dziki, M; Turski, WA; Urbanska, E, 1991) |
| "Initially, a dose sufficient to cause convulsions (CD) was given followed by twice the CD (2 x CD), which was administered 48 h later." | ( Arthur, GR; Covino, BG; Doucette, AM; Feldman, HS; Hurley, R; Pitkanen, M, 1991) |
| "Changes in inhibition during seizure development were monitored by administering pulse pairs at regular intervals." | ( Ivy, GO; Khurgel, M; Milgram, NW; Racine, R; Yearwood, T, 1991) |
| "Both PTX and Ro 5-4864 produced myoclonic seizures, primarily between 15-40 min after administration; myoclonus was followed by more severe seizures after PTX." | ( Dai, KS; Woolley, DE, 1991) |
| "Pretreatment were pancuronium prevented convulsions and hyperthermia, but had no effect on acidemia or changes in cardiovascular parameters after intravenous (i." | ( Davis, WM; Hackett, RB; Obrosky, KW; Waters, IW, 1991) |
| "Generalized convulsion appeared after intraperitoneal administration of 50 mg/kg PTZ with a latency of 68." | ( Fujimoto, H; Hashiguchi, S; Kawai, H; Masuda, T; Saito, S, 1990) |
| "To determine the adequacy of seizure control and the adverse effects of administering an IV loading dose of phenytoin by constant infusion pump." | ( Cline, D; Donovan, PJ, 1991) |
| "On the other hand, BIC-induced seizures in both groups were suppressed by IPR pretreatment." | ( Mutoh, F, 1991) |
| "Treatment of hyponatremic seizures with routine anticonvulsants may be ineffective and is associated with a considerable incidence of apnea." | ( Fleischmann, L; Hackbarth, R; Meert, K; Sarnaik, AP, 1991) |
| "Clonic seizures induced in mice by intracerebral administration of N-methyl-D-aspartate, kainate or quisqualate were used to study the anti- and proconvulsant potential of antiepileptic drugs and beta-carbolines." | ( Niemann, W; Stephens, DN; Turski, L, 1990) |
| "Studies of the treatment of intractable seizures (unsatisfactory control of seizure) indicate that more complex cases may require the data obtained with EEG video monitoring." | ( Erlichman, M, 1990) |
| "In the present study, limbic seizures induced by systemic administration of kainic acid resulted in substantial increases in the TRH content of posterior cortex and of dorsal and ventral hippocampus, and in moderate elevations in anterior cortex, amygdala/piriform cortex and corpus striatum." | ( Kreider, MS; Winokur, A; Wolfinger, BL, 1990) |
| "MK-801 treatment reduced overall seizure score and proportion of rats seizing." | ( Janowsky, DS; Morrisett, RA; Overstreet, D; Rezvani, AH; Swartzwelder, HS; Wilson, WA, 1990) |
| "When administered i." | ( Kanai, Y; Manabe, S; Wada, O, 1990) |
| "Treating seizures is a major part of a neurologic practice." | ( Bernstein, AL, 1990) |
| "In contrast, generalized motor seizures evoked by [NMe-Phe3-D-Pro4]morphiceptin were potentiated and prolonged in colchicine-pretreated animals as status epilepticus (sustained clonus of forepaws and head for more than 1 h) was observed in both unilateral and bilateral colchicine-pretreated animals but not in control rats." | ( Hong, JS; Lee, PH, 1990) |
| "NMDA-induced convulsions were antagonized in a dose-related manner by prior administration of the NMDA antagonists cis-(+/- )-4-phosphonomethyl-2-piperidine carboxylic acid (CGS19755), cis-(+/- )-4-(2H-tetrazol-5-yl)methyl-piperidine-2-carboxylic acid (LY233053), (+/- )3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid (CPP), D,L-2-amino-5-phosphonovalerate (D,L-AP5) and MK801." | ( Gamble, AY; Johnson, BG; Ornstein, PL; Salhoff, CR; Schoepp, DD, 1990) |
| "Pilocarpine seizures were blocked by systemic administration of benzodiazepines, barbiturates, valproate and trimethadione, while diphenylhydantoin did not affect, and ethosuximide increased the susceptibility of rats to such seizures." | ( Andrews, JS; Bortolotto, ZA; Bressler, K; Calderazzo-Filho, LS; Cavalheiro, EA; Löschmann, PA; Turski, L, 1990) |
| "Normeperidine-induced seizures in patients with porphyria may be treated by withdrawal of meperidine therapy and selective use of anticonvulsants." | ( Deeg, MA; Rajamani, K, 1990) |
| "Both convulsions and mortality percentages are more significantly reduced in treated animals with these two substances in combination rather than separately." | ( Bertelli, A; Bertelli, AA; Giovannini, L; Spaggiari, P, 1990) |
| "However, the seizures initiated 1 day after drug administration were dose-dependently suppressed." | ( Abraham, WC; Bilkey, DK; Takazawa, A, 1990) |
| "In contrast to the potent effect on the seizure threshold, the severity or duration of seizures, evoked in phenytoin-pretreated rats by increasing the current, was not reduced." | ( Hönack, D; Löscher, W; Rundfeldt, C, 1990) |
| "By using a rat seizure model, a comparison of the antiseizure activity of 12 dihydropyridine calcium channel antagonists (administered i." | ( Morón, MA; Stevens, CW; Yaksh, TL, 1990) |
| "The odds ratios of seizure induction in the CsA-treated groups versus placebo group were 1." | ( Christenson, M; Fisher, RS; Fivush, B; McCrindle, BW; Racusen, LC, 1990) |
| "Protection against convulsions induced by cyanide was observed after treatment with alpha-ketoglutarate, either alone or in combination with sodium thiosulfate, a classical antagonist for cyanide intoxication." | ( Yamamoto, H, 1990) |
| "A 93-year-old woman without a known seizure history, while on ciprofloxacin and theophylline combined therapy, experienced a grand mal seizure." | ( Bentley, DW; Karki, SD; Raghavan, M, 1990) |
| "Generalized tonic clonic seizures continued despite conventional therapy." | ( Dean, BS; Goetz, CM; Krenzelok, EP; Lopez, G, 1990) |
| "The duration of seizure was shorter with propofol in both treatments but there was significant drug-time interaction." | ( Boey, WK; Lai, FO, 1990) |
| "The role of seizure-induced cell death was investigated by recording the EEG in monkeys and in rats treated with phenobarbital." | ( Dasheiff, RM; Ramirez, LF, 1985) |
| "This seems to imply that seizures become harder to suppress as they recur--a possibility which argues for the early initiation of anticonvulsant therapy." | ( Burnham, WM; Mace, JA, 1987) |
| "Convulsive seizures are a potential side effect of antidepressant drug treatment and can be produced by all classes of antidepressants." | ( Ikeda, M; Knapp, RJ; Malatynska, E; Yamamura, HI, 1988) |
| "Knowledge of a strain's seizure susceptibility to the GABA antagonist or of its sensitivity to the hypnotic effects of ETOH were of no predictive value in estimating the outcome of coadministration studies, suggesting at least partially separate genetic influences on each phenotype." | ( Dudek, BC; Phillips, TJ, 1989) |
| "The incidence of convulsions increased 3 days after starting GES administration, and this effect continued throughout the 6 months of drug administration." | ( Edamatsu, R; Higashihara, Y; Hiramatsu, M; Kabuto, H; Mori, A, 1989) |
| "Focal, limbic seizures were produced by systemically administered pilocarpine (200 mg/kg, i." | ( Barone, P; Campanella, G; Chase, TN; Marin, C; Palma, V; Parashos, SA, 1989) |
| "In order to investigate the effects of seizures on manganese distribution in the body, rats were treated with kainic acid to produce spontaneous seizures which were quantitated for number and severity." | ( Carl, GF; Critchfield, JW; Gallagher, BB; Holmes, GL; Hurley, LS; Keen, CL; McGinnis, LS; Thompson, JL; Wheeler, GA, 1989) |
| "Five patients with seizures related to imipenem administration are described." | ( Chmel, H; Eng, RH; Munsif, AN; Smith, SM; Yangco, BG, 1989) |
| "We favor treatment of a single seizure in patients with HIV infection." | ( Holtzman, DM; Kaku, DA; So, YT, 1989) |
| "The potentiation of seizures and death by 2 mg/kg nifedipine pretreatment was further shown by challenge with three different doses of cocaine." | ( Albertson, TE; Derlet, RW, 1989) |
| "In animals that presented convulsion a stereotyped gnawing and/or licking behavior was observed immediately after the ictus activity as a consequence of the combined acute administration of haloperidol and picrotoxin." | ( Palermo-Neto, J; Sandoval, MR, 1989) |
| "Four adult men with resistant partial seizures underwent an intensive open-label protocol designed to evaluate long-term add-on lamotrigine (LTG) therapy." | ( Ashworth, M; Keally, M; Kupferberg, H; Mikati, MA; Osborne-Shafer, P; Schachter, SC; Schomer, DL; Seaman, CA; Sheridan, PH; Valakas, A, 1989) |
| "The effects of seizures induced by an acute administration of bicuculline have been investigated on the central benzodiazepine and adenosine receptors in developing rats and in adults." | ( Daval, JL; Sarfati, A, 1987) |
| "At a dose of 70 pmol seizures occurred for half of the treated rats." | ( Bidard, JN; Gandolfo, G; Gottesmann, C; Lazdunski, M; Mourre, C, 1987) |
| "Thus, myoclonic seizures were observed in 30% and 80% of the animals by the third and the eighth day of treatment, respectively." | ( Biggio, G; Corda, MG; Giorgi, O; Mele, S, 1987) |
| "Hyponatremia should be considered when seizures or mental changes occur in patients treated with DDP." | ( Ritch, PS, 1988) |
| "Definition of other pathways of seizure development and the effects of pharmacologic treatments on discrete brain regions await further research efforts." | ( Gale, K, 1988) |
| "Soman (100 micrograms/kg; sc) produced convulsions in 63% of the saline-pretreated rats, whereas with LiCl pretreatment all rats exposed to 100 micrograms/kg of soman had tonic-clonic convulsions." | ( Nelson, SR; Pazdernik, TL; Samson, FE; Savolainen, KM, 1988) |
| "Kindled seizures were almost completely blocked by treatment with carbamazepine, whereas the effect of valproic acid was partial, suppressing only generalized seizures." | ( Higuchi, T; Igarashi, Y; Kato, N; Minatogawa, Y; Nagaki, S; Ohshima, H; Takazawa, A; Watanabe, N; Yamazaki, J; Yamazaki, O, 1986) |
| "The analgesic treatments lowered the seizure threshold considerably in 5 out of 6 dogs, and fentanyl and pentazocine led to an increased incidence of clonic-tonic seizures after the end of the pentetrazole infusion." | ( Czuczwar, SJ; Frey, HH; Scherkl, R, 1986) |
| "Postdecapitation convulsions were analyzed in rats after the administration of a variety of adrenergic and serotonergic agents." | ( Gonzales, DA; Peroutka, SJ; Shapiro, M, 1987) |
| "Reasons for the occurrence of these seizures despite treatment are discussed within the context of the differential potency that exists among benzodiazepines in binding to central and peripheral benzodiazepine receptors." | ( Pawluczyk, S; Schneider, LS; Syapin, PJ, 1987) |
| "RO 15-3505 induced seizures in mice treated with a subconvulsant dose of pentylenetetrazole, the most efficient doses being 3 and 6 mg/kg." | ( Belzung, C; Misslin, R; Vogel, E, 1988) |
| "We conclude that 1) bicuculline-induced seizures result in pial arteriolar dilation and increased CBF; 2) CSF levels of prostanoids increase during seizures; and 3) pretreatment with indomethacin severely blunts increases in CBF during seizures." | ( Busija, DW; Leffler, CW, 1989) |
| "In kindled rats, 31 days after the last seizure, the number of GABA-immunoreactive cells that could be observed after AOAA-treatment was significantly lower (35% ipsilateral and 25% contralateral) when compared to AOAA-treated controls." | ( Huisman, E; Kamphuis, W; Lopes da Silva, FH; Wadman, WJ, 1989) |
| "In the work reported here, audiogenic seizure susceptibility and brain tryptophan and serotonin concentrations were measured in DBA/2J mice after administration of three doses of L-tryptophan or p-chlorophenylalanine." | ( Lack, DB; Peters, RI, 1985) |
| "Pentylenetetrazole and picrotoxin seizure thresholds, measured during constant rate iv infusion, were significantly lowered by pretreatment with diazepam (250 mg/kg) and Ro 15-1788 (20 mg/kg) administered 30 and 20 minutes, respectively, before seizure threshold measurement." | ( Bourn, WM; Garrett, RL, 1985) |
| "Like 1 and 2, tonic-clonic seizures were induced when trans-3 or -4 were administered to mice intracerebroventricularly." | ( Enna, SJ; Fung, YK; Patch, RJ; Witiak, DT, 1986) |
| "Fluid restriction and treatment of seizures with phenobarbital are widely used therapies." | ( Donn, SM; Goldstein, GW; Schork, MA, 1988) |
| "Protection against sound-induced seizures was observed after intraperitoneal administration of flunarizine (5-40 mg/kg)." | ( De Sarro, GB; Meldrum, BS; Nistico, G, 1986) |
| "By contrast, pentylenetetrazol seizures' characteristics were significantly changed in response to the intraperitoneal administration of the norepinephrine antagonist, 6-hydroxydopamine, by abolishing the tonic and clonic phases of the seizure." | ( Abed, WT, 1986) |
| "The electrographic seizure produced by GBL was significantly prolonged and more severe in the 6-OHDA-treated animals." | ( Snead, OC, 1987) |
| "Protection against sound-induced seizures was observed after intraperitoneal administration of denzimol (3-15 mg/kg)." | ( Ascioti, C; De Sarro, GB; Libri, V; Nistico, G; Testa, R, 1987) |
| "A decrease of the triggered seizure duration occurred during the high-dose treatment." | ( Kurachi, M; Minabe, Y; Tsutsumi, M, 1988) |
| "Children with seizure disorders frequently are treated with anticonvulsant medications such as clonazepam, valproic acid, carbamazepine, and ethosuximide, which cannot be given parenterally." | ( Laney, SM; Woody, RC, 1988) |
| "The threshold of the generalized clonic convulsions induced by intravenous infusion of pentylenetetrazol (PTZ) was significantly increased by the intraperitoneal administration of noradrenaline (NA) neurotoxin, 6-hydroxydopamine, which produced no changes in the levels of catecholamines in discrete areas of rat brain, but the effect was accompanied by spinal depletion of NA." | ( Abed, WT, 1988) |
| "The pharmacotherapy of minor seizures depends on the type of epileptic manifestation." | ( Hess, CW, 1988) |
| "Eleven children with seizures were treated with clonazepam by rectal route." | ( Bildstein, G; Cano, JP; Chateauneuf, R; Fornaris, M; Netter, JC; Petrus, M, 1988) |
| "Both seizures and sprouting were seen in 32% of the treated animals." | ( Cronin, J; Dudek, FE, 1988) |
| "Theophylline can cause life-threatening seizures when administered in excessive doses." | ( Levy, G; Yasuhara, M, 1988) |
| "Protection against sound-induced seizures was given after intraperitoneal administration of AVM (30 and 50 mg/kg)." | ( Ammendola, D; De Sarro, A; De Sarro, GB; Germanà, G; Naccari, F; Rotiroti, D, 1988) |
| "The effect of bicuculline-induced convulsive seizures on lipid metabolism has been studied in four brain areas (cerebellum, cerebral cortex, hippocampus, and brainstem) using [2-3H]glycerol and [1,2-14C]ethanolamine as radioactive lipid precursors administered simultaneously with bicuculline." | ( Arienti, G; Corazzi, L; Marku, N; Piccinin, GL, 1988) |
| "In rats, caerulein failed to affect the seizures caused by intraventricular administration of quinolinic acid." | ( Allikmets, LKh; Prakh'e, IB; Ryzhov, IV; Soosaar, AKh; Vasar, EE, 1988) |
| "The average time to onset of seizures induced by fluorothyl in control mice was 510 sec; pretreatment with oral doses of 1000, 1500 and 2000 mg/kg of aspartame 1 hr earlier significantly reduced the time required to elicit seizures (394, 381 and 339 sec, respectively)." | ( Maher, TJ; Pinto, JM, 1988) |
| "The incidence and severity of convulsions were monitored in individual rats until they were sacrificed by focused microwave irradiation of the head at the following time points after soman administration: 4 min, a time prior to the onset of convulsions; 10 min, the time of onset of convulsions; 1 h, the time of peak convulsive activity; and 6 h, a time at which rats were recovering from convulsions." | ( Ho, IK; Hoskins, B; Liu, DD; Ueno, E, 1988) |
| "Five neonates treated with PB alone for seizures were studied." | ( Bhargava, VO; Garrettson, LK, 1988) |
| "The convulsive-seizure-increasing effect of AT II was enhanced after multiple administration of pimozide and particularly after its withdrawal for 21 days." | ( Georgiev, V; Kambourova, T; Petkova, B, 1988) |
| "Peak inhibition of severity of seizures occurred at 1 hr after administration with an ED50 of 17." | ( Heit, MC; Schwark, WS, 1988) |
| "The behavioral topography of the convulsions and the neuroanatomical distribution and nature of the subsequent pathology closely resemble that observed with systemic administration of these compounds." | ( McDonough, JH; McLeod, CG; Nipwoda, MT, 1987) |
| "Bicuculline and picrotoxin convulsions were not significantly affected by MPTP treatment." | ( Castorina, M; DeMattei, M; Fariello, RG; Ferraro, TN; Golden, GT, 1987) |
| "In an infant with neonatal seizures, CSF GABA levels were determined before and after treatment with vitamin B6." | ( Dominick, HC; Kurlemann, G; Löscher, W; Palm, GD, 1987) |
| "Because seizures may follow ingestion of certain amounts, appropriate treatment is needed, including the use of anticonvulsants." | ( Siegel, E; Wason, S, 1986) |
| "CNS excitation and seizures, manifestations of organochlorine intoxication, can occur following ingestion or inappropriate application of the 1 per cent topical formulation of lindane used to treat scabies and lice." | ( Mortensen, ML, 1986) |
| "Male Long-Evans rats experienced three convulsions induced by intravenously administered pentylenetetrazol (PTZ) and were then kindled by electrical stimulation of the olfactory bulb or amygdala." | ( Gramlich, CA; Stripling, JS, 1987) |
| "Four cases of convulsive seizures occurring during treatment with nomifensine have been notified to the Committee on the Safety of Medicines of the United Kingdom, and 22 cases have been reported from other countries." | ( Edwards, JG; Glen-Bott, M, 1987) |
| "The resistance of seizures produced by PILO in rats to antiepileptic drugs reaffirms the clinically obvious lack of effective treatments for limbic convulsions." | ( Cavalheiro, EA; Coimbra, C; da Penha Berzaghi, M; Ikonomidou-Turski, C; Turski, L; Turski, WA, 1987) |
| "Prevention of convulsions with phenobarbitone administered immediately before diazinon, resulted in neither the development of lactic acidosis nor mobilization of muscle glycogen or activation of glycogen phosphorylase." | ( Husain, K; Matin, MA; Mirza, MA, 1987) |
| "Management of seizures requires prompt medical attention to prevent morbidity and mortality and to clarify the etiology of the event so that proper long-range therapy can be planned." | ( Bean, SC, 1986) |
| "Both compounds antagonized MES-induced seizures after administration to mice; oral ED50 values for 3 and 4 were 3." | ( Beedle, EE; Clark, CR; Lawson, R; Leander, JD; Parli, CJ; Potts, BD; Robertson, DW, 1987) |
| "One child treated with FB exhibited seizures on the second day and six children showed drowsiness and bradycardia on the last two days, that were attributable to high levels of FB." | ( Chunga, F; Durán, JA; Serrano, JS; Valls, A; Vela, F, 1987) |
| "Unlike kainate, TMT produced seizures in only a subset of treated animals and with a latency of days rather than minutes." | ( Dempster, DW; Sloviter, RS; von Knebel Doeberitz, C; Walsh, TJ, 1986) |
| "The thresholds for inducing the maximal seizure by pentylenetetrazole (PTZ) were compared for BDF1 mice of both sexes with varying ages after intraperitoneal administration of various doses of PTZ." | ( Kanai, S; Kitani, K; Masuda, Y; Nokubo, M; Ohta, M; Sato, Y, 1986) |
| "At age 16 to 17 days, seizures were induced in the cannulated rats and naive (intact) controls by exposure to flurothyl following pretreatment with the GABA agonist, muscimol, or vehicle." | ( Moshe, SL; Okada, R; Sperber, EF; Wong, BY; Zhao, DY, 1986) |
| "A patient with seizures, coma and respiratory depression after pentazocine overdose was treated successfully with naloxone and artificial ventilation." | ( Bear, R; Gesztes, T; Roytblat, L, 1986) |
| "Seven neonatal patients with severe seizures unresponsive to conventional anticonvulsant therapy were treated with lorazepam." | ( Deshmukh, A; Mangurten, HH; Schnitzler, E; Wittert, W, 1986) |
| "Duration of freedom from seizures following acute therapy was independent of LOR dosage." | ( Crawford, TO; Mitchell, WG; Snodgrass, SR, 1987) |
| "Generalized convulsive seizures can be triggered by sensory stimuli in animals treated with subthreshold levels of convulsant drugs." | ( Caspary, DM; Faingold, CL; Hoffmann, WE, 1985) |
| "Psychosis and/or seizures following the administration of intramuscular penicillin G procaine have not been reported in the pediatric literature to our knowledge." | ( D'Angelo, L; Silber, TJ, 1985) |
| "We studied 15 children with complex partial seizures in whom one or more seizure type was exacerbated during treatment with carbamazepine." | ( Hosey, LC; Snead, OC, 1985) |
| "In this model, tonic-clonic seizures are easily elicited by handling and the effects of administration of carbamazepine (CBZ), phenytoin (DPH), phenobarbital (PB), diazepam, valproic acid (VPA) and ethosuximide were quantitatively evaluated." | ( Abbott, LC; Bennett, GD; Finnell, RH; Taylor, SM, 1985) |
| "Three adolescent patients with severe seizure disorders were treated with phenacemide." | ( Baska, RE; Duggan, E; Hellerstein, S; Hoffman, L; Lea, K, 1986) |
| "However, the incidence of convulsions was increased by FLA-63 in rats pretreated with the catecholamine precursor L-dihydroxyphenylalanine." | ( Blask, DE; Stockmeier, CA, 1986) |
| "In four patients the seizure followed the institution of maprotiline therapy by less than three weeks." | ( Bryan, GE; Gunderson, CH; Jabbari, B; Marsh, EE, 1985) |
| "The appearance of convulsion induced by I-nicotine in mice was also inhibited by pretreatment with d-nicotine." | ( Ishikawa, T; Nagata, M; Osumi, Y, 1985) |
| "The binding sites from seizure sensitive and resistant mice were equally affected by treatment with dithiothreitol, trypsin or heat." | ( Collins, AC; Marks, MJ; Miner, LL, 1985) |
| "The latency to clonic convulsion was dramatically affected by prior shock treatment, and the direction of this change depended upon the escapability/inescapability of the shock." | ( Alpern, HP; Drugan, RC; Maier, SF; McIntyre, TD, 1985) |
| "These prolonged seizures remained with chronic (10 days) treatment but an anticonvulsant effect of phenytoin (40 and 75 mg/kg) also emerged, shown by a decrease in the incidence of seizures." | ( File, SE; Pellow, S; Wilks, L, 1985) |
| "Grand mal seizures were observed in unanesthetized animals (+/-SD) 133+/-37 min after administration of insulin, at a time when brain glucose was normal, but brain tissue content of Na(+), K(+), osmoles, and water was significantly greater than normal." | ( Arieff, AI; Doerner, T; Massry, SG; Zelig, H, 1974) |
| "The treatment was found to prevent seizures induced by pentylenetetrazol." | ( Mizutani, A; Sano, M; Seto-Ohshima, A, 1984) |
| "The rise in seizure threshold still occurred when animals were pretreated with alpha-methyl-p-tyrosine (200 mg ." | ( Cowen, PJ; Green, AR; Nutt, DJ, 1981) |
| "Changes in leptazol (pentetrazol) seizure susceptibility after successive treatments of mice with tryptophol, a neutral metabolite of indoleamine, in combination with ethanol have been examined." | ( Fukumori, R; Kitagawa, H; Minegishi, A; Satoh, T, 1981) |
| "In mice, running, clonic and tonic convulsions and lethality were assessed following transcorneal (electroshock) current or convulsant drugs, each administered alone and after cannabidiol (CBD) pretreatment." | ( Benedito, MA; Carlini, EA; Consroe, P; Leite, JR; Mechoulam, R, 1982) |
| "tremor, myoclonus and convulsions, successively appear, have been studied in fed and fasted rats with and without pretreatment with 2-amino-7-phosphonoheptanoic acid (180 mg/kg)." | ( Halsey, MJ; Meldrum, BS; Wardley-Smith, B, 1984) |
| "Generalized tonic-clonic convulsions appeared with typical changes in the electroencephalogram 7-35 s after administration of the epileptogenic drugs." | ( Goitein, KJ; Shohami, E, 1983) |
| "Except for single seizure episodes in five patients, GAG therapy was well tolerated." | ( Agid, Y; Böhlen, P; Bonnet, AM; Chazot, G; Coquillat, G; Fischer, C; Koch-Weser, J; Schechter, PJ; Tell, G, 1981) |
| "Following these treatments, seizure thresholds to these drugs were measured by an IV infusion method to minimise problems of systemic uptake and metabolism of the drugs." | ( Batts, CC; Cowen, PJ; Grahame-Smith, DG; Green, AR; Nutt, DJ, 1982) |
| "Electroconvulsive seizures administered during the period of fetal benzodiazepine (BZ) binding site proliferation (days 16, 18 and 20 in gestation) significantly decreased the density of cerebral cortical benzodiazepine binding sites in exposed pups up to 21 days postnatal age." | ( Gallager, DW; Wakeman, EA, 1982) |
| "Administration of THC during the seizure-insensitive period resulted in genotype-dependent alternations in photocell activity and sprawling." | ( Consroe, P; Fish, BS, 1983) |
| "We think this decline is caused by seizures since phenobarbital pretreatment prevented the appearance of limbic seizures and blocked the receptor decline." | ( Dasheiff, RM; Fanelli, RJ; Kraus, VM; McNamara, JO, 1983) |
| "These electrographic seizures were not opiate specific since this activity occurred undiminished in naltrexone-pretreated animals and was even potentiated in animals pretreated for 6 days with increasingly higher doses of systemic morphine." | ( Frenk, H; Mayer, DJ; Miller, J; Watkins, LR, 1984) |
| "More animals with clonic seizures were seen in the DPA-treated group which had been subjected to selective depletion of spinal serotonin or treated with methysergide than in DPA-treated controls." | ( Bendotti, C; Lazarova, M; Samanin, R, 1983) |
| "The role of forebrain noradrenaline in seizures induced by electrical stimulation of the anterior neocortex (kindling) was investigated in control rats and rats pretreated with bilateral injections of 6-hydroxydopamine (6-OHDA) into the mesencephalic trajectory of the dorsal tegmental noradrenergic bundle." | ( Altman, IM; Corcoran, ME, 1983) |
| "Six cases of convulsive seizures occurring during treatment with viloxazine notified to the Committee on Safety of Medicines (CSM) and two other cases from Japan were reviewed." | ( Edwards, JG; Glen-Bott, M, 1984) |
| "In the case of picrotoxin induced convulsive seizures where there is an alteration at the GABA receptor level, ther is a lack of efficiency after nDPA treatment which increases GABA at the synaptic level." | ( Ciesielski, L; Mandel, P; Simler, S, 1981) |
| "Six cats with stable seizure thresholds were treated with 150 mg/kg of chloramphenicol or its cogener, thiamphenicol, at 12-h intervals over a 30-h period." | ( Belsito, O; Bowersox, SS; Shouse, MN, 1984) |
| "Using treatments which produce generalized seizures (electroconvulsive shock, strychnine, and flurothyl) and gamma amino-butyric acid (GABA) antagonists (picrotoxin, bicuculline, and pentylentetrazol), the ED50 for seizures was determined in the selected lines." | ( Crabbe, JC; McSwigan, JD; Young, ER, 1984) |
| "In animals displaying lidocaine-kindled convulsions there were marked increases in glucose utilization in either the hippocampus and amygdala or in perirhinal cortical areas during the seizure administration; these animals also displayed long-lasting increases in irritable behavior." | ( Ingvar, DH; Kennedy, C; Miyaoka, M; Post, RM; Shinohara, M; Sokoloff, L; Squillace, K; Suda, S, 1984) |
| "A study of the effects of MNPC on convulsions induced by chemicals which interfere with GABA-mediated neurotransmission was carried out in the mouse, with MNPC being administered by subcutaneous injection 30, 60 or 90 min prior to challenge with bicuculline." | ( Crider, AM; Hinko, CN; Seibert, K, 1984) |
| "In the maximal pentetrazol seizures test in rats denzimol showed a profile similar to that of phenytoin and carbamazepine, but different from that of barbiturates and benzodiazepines so that it is suggested that its clinical application would be that of "grand mal" and psychomotor type seizures therapy." | ( Barbadoro, E; Graziani, G; Testa, R; Tirone, F, 1983) |
| "The intensity of sound-induced convulsions in the genetically epilepsy-prone rat (GEPR) was reduced in a dose related fashion by intracerebroventricular administration of dobutamine, (beta 1 agonist), terbutaline (beta 2 agonist) or phenylephrine (alpha 1 agonist)." | ( Dailey, JW; Jobe, PC; Ko, KH, 1984) |
| "Protection against sound-induced seizures occurred after intraventricular administration of (+/-)cis-2,3-piperidine dicarboxylic acid (0." | ( Collins, JF; Croucher, MJ; Meldrum, BS, 1984) |
| "In the same animals the occurrence of clonic seizures was scored as to time of onset and severity for 20 min after drug administration." | ( Carney, JM; Johnson, P; Rennert, OM; Seale, TW, 1984) |
| "Amygdaloid kindled generalized convulsion was reversibly blocked despite continued afterdischarge generation by amygdaloid stimulation for about 60 h following intracerebral administration of gabaculine, a GABA-transaminase inhibitor, into the substantia innominata (SI) ipsilateral to the side of amygdaloid kindling." | ( Okamoto, M; Wada, JA, 1984) |
| "A progressive development of seizure activity after this treatment was observed." | ( Diehl, RG; Gotwo, T; Smialowski, A, 1984) |
| "Electrographic seizure activity was recorded shortly following naxolone injections in artificially ventilated, methadone-treated stump-tailed macaques." | ( Beck, EC; Dustmann, RE; Shearer, DE; Snyder, EW, 1980) |
| "Methionine alone did not induce convulsions when administered by various routes in dosages of 250--13,000 mg/kg, although larger doses of methionine (500--4,000 mg/kg) decreased behavioral activity." | ( Freed, WJ; Gillin, JC; Luchins, DJ; Taylor, SP; Wyatt, RJ, 1980) |
| "These seizures are indistinguishable in quality from those induced by pentylenetetrazol (PTZ), and pretreatment with low doses of caffeine potentiates PTZ-induced seizures." | ( Marangos, PJ; Martino, AM; Paul, SM; Skolnick, P, 1981) |
| "The sensitivity to insulin hypoglycemic convulsions has been shown to decrease at early times (16 and 24 hr) and increase at later times (1 week) after gold thioglucose (GTG) treatment." | ( Fish, KW; Holliday, JF; Luby, JL; Marrazzi, MA, 1981) |
| "We also treated a single case of tonic-clonic seizure after intracranial spill of metrizamide in a patient without a history of seizure disorder, and a case of myoclonus following a thoracic metrizamide myelogram that showed a highgrade block." | ( Hayward, JN; Killebrew, K; Scatliff, JH; Whaley, RA, 1983) |
| "5 Factors that might predispose to seizures include relevant family and past medical history, starting treatment, a change in dose, benzodiazepine withdrawal and concomitant treatment with other drugs that have epileptogenic properties." | ( Edwards, JG; Glen-Bott, M, 1983) |
| "The slowed rate of seizure development was not significant if the kindling stimuli were initiated 6 days posthaloperidol treatment nor if 10-mg doses of haloperidol were used for 30 days." | ( Gee, KW; Hollinger, MA; Killam, EK, 1983) |
| "Since the effectiveness of seizure prophylaxis has not been established, the authors suggest that anticonvulsant drugs be administered only after an early seizure has occurred." | ( Bean, JR; Haack, D; Norton, JA; Rapp, RP; Tibbs, PA; Young, B, 1983) |
| "It appeared to inhibit seizure activity, subsequently allowing the patient to be treated with hyperbaric oxygen." | ( Weaver, LK, 1983) |
| "On day 3 a convulsion was induced by electricity in half of the rats (controls and barbital-treated) and 1 h later the sensitivity to hexobarbital was determined with a threshold test." | ( Wahlström, G, 1983) |
| "During seizure threshold determinations, aminophylline pretreatment markedly prolonged afterdischarge durations without significantly changing seizure severity or threshold." | ( Albertson, TE; Bowyer, JF; Joy, RM; Stark, LG, 1983) |
| "A total of 26 neonates with seizures had an EEG while on phenobarbital therapy." | ( Bickford, RB; Coen, RW; Scholl, ML; Staudt, F, 1982) |
| "No significant changes in seizure-grade distribution, as compared to controls, were observed in any of the TCT- or TPhT-treated groups at any of the time points examined." | ( Doctor, SV; Fox, DA, 1982) |
| "As a seizure was observed in two of our cases after administration of this barbiturate, an EEG study was performed." | ( Ginet, J; Meigner, M; Nogues, B; Souron, R; Vecchierini-Blineau, MF, 1982) |
| "Furthermore, post-decapitation convulsions were eliminated in DSP-4 treated animals." | ( Asin, KE; Fibiger, HC; Wirtshafter, D, 1982) |
| "Prominal reduced the severity of convulsions in pp'DDT-treated animals." | ( Jaffery, FN; Matin, MA; Siddiqui, RA, 1981) |
| "Epileptiform seizures resistant to treatment with diazepam and barbiturates were frequent and probably not solely caused by cerebral ischaemia." | ( Holm, HA; Kittang, E; Laake, K; Refstad, SO, 1981) |
| "The maximal seizure was induced by administering an electric shock through the eyes." | ( Fujii, T; Hironaka, T; Morimoto, S; Nakanishi, H; Ohtaki, Y, 1981) |
| "Behavioral seizures reappeared 2 to 3 days after termination of GAG treatment." | ( Myslobodsky, MS; Valenstein, ES, 1980) |
| "The rate and pattern of seizure development provoked by repeated electrical stimulation of the amygdala (kindling) was assessed in rats that had been pretreated with intracerebral injections of the selective catecholaminergic neurotoxin 6-hydroxy-dopamine." | ( Corcoran, ME; Mason, ST, 1980) |
| "Convulsive seizures occurred only after the im doses that were lethal, but they were observed after administration of iv doses that were nonlethal." | ( Henry, MC; Levine, BS; Port, CD; Rosen, E, 1980) |
| "A progression from encephalopathy to seizures was observed following aminophylline administration." | ( Chu, NS, 1981) |
| "When seizures were preceded by antihypertensive treatment with the alpha-adrenergic antagonist, phentolamine, peak blood pressure tended to remain near the baseline level and lower than sham-injected controls." | ( Kanter, RK; Sauro, MD; Strauss, JA, 1995) |
| "El mouse convulsions were inhibited by oral administration of citalopram for 2 weeks." | ( Kabuto, H; Kurimoto, T; Mori, A; Takei, M; Yokoi, I, 1994) |
| "Felbamate was also potent to prevent seizures induced by administration of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA), an AMPA/kainate receptor agonist (ED50 = 11." | ( Aguglia, U; Bertorelli, R; De Sarro, A; De Sarro, G; Ongini, E, 1994) |
| "The kainate-elicited convulsions and NO formation were attenuated in animals pretreated with either 7-nitroindazole, a specific inhibitor of neuronal NO synthase, or diazepam." | ( Busse, R; Mordvintcev, PI; Mülsch, A; Nielsen, EO; Olesen, SP; Scheel-Krüger, J; Vanin, AF, 1994) |
| "There was no difference in seizure duration before or after D-NA administration." | ( Albrecht, RF; Baughman, VL; Pelligrino, DA; Theard, MA; Wang, Q, 1995) |
| "We investigated whether the severity of convulsions evoked by kainic acid and pilocarpine is modified in nitric oxide synthase inhibitor-treated rats." | ( Barbier, P; Corsini, GU; Donati, E; Fumagalli, F; Maggio, R; Racagni, G; Riva, M, 1995) |
| "Behavioral characteristics of seizures have age-dependent features, which suggests that effective treatment of seizures may be age-specific as well." | ( Moshé, SL; Ortíz, J; Ptachewich, Y; Shinnar, S; Velísek, L; Velísková, J, 1995) |
| "A newborn girl with seizures was, after repeated conventional anticonvulsive treatment, cured by pyridoxine administration." | ( Bosschaart, AN; Hageman, G; Tummers, RF; van Waarde, WM, 1995) |
| "The fluoxetine effect on HIP seizures was also assessed following long-term treatment with gepirone, a 5-HT1A receptor agonist." | ( Hasegawa, H; Nakamura, M; Shiraishi, J; Wada, Y, 1995) |
| "In patients without seizures before therapy, seizures occurred during therapy in 5 of 82 patients (6%) receiving meropenem and in 1 of 86 patients (1%) receiving cefotaxime (95% confidence interval: -0." | ( Dagan, R; Klugman, KP, 1995) |
| "Patients with ALL and seizures were identified retrospectively by review of the records of all pediatric ALL patients who were diagnosed and treated during the years 1983 through March 1993 in a large tertiary-care hospital." | ( Eviatar, L; Grossman, R; Karayalycin, G; Lanzkowsky, P; Maytal, J; Schaul, N; Shende, AC; Yusuf, FH, 1995) |
| "We compared the duration of seizure activity and cognitive recovery profiles after different doses of methohexital, propofol, and etomidate administered to induce hypnosis prior to ECT." | ( Avramov, MN; Husain, MM; White, PF, 1995) |
| "PTZ-induced convulsions were partly antagonized by the GVG treatment." | ( Sayin, U; Timmerman, W; Westerink, BH, 1995) |
| "Spontaneous recurrent seizures are registered during the long-term period following the systemic administration of PILO in rats." | ( Cavalheiro, EA; Leite, JP, 1995) |
| "This was indicated by a higher mean convulsion score, increased number of mice responding with convulsions, and induction of seizures in animals pretreated with a subepileptic dose of pentylenetetrazol." | ( Ashkenazi, S; Dinari, G; Weizman, A; Yuhas, Y, 1995) |
| "administration." | ( Baron, BM; Chapman, AG; Dürmüller, N; Harrison, BL; Meldrum, BS; Parvez, N, 1995) |
| "We report two cases of seizures and one case of hand cramping and finger paresthesia after starting foscarnet therapy with no evidence of predisposing risk factors, such as serum laboratory abnormalities, renal dysfunction, or known central nervous system (CNS) involvement." | ( Liu, YQ; Lor, E, 1994) |
| "To assess whether electrically induced seizures are indeed required for the appearance of the blunted pineal response to isoproterenol, pineal and serum melatonin levels were measured after isoproterenol stimulation in rats treated with ECS (80 mA, 0." | ( Amaro, S; d'Istria, M; De Luca, B; Maj, M; Monteleone, P; Serino, I, 1994) |
| "Five of 6 patients developing seizures received anticonvulsant and supportive treatment with resolution of neurologic abnormalities." | ( Bernaudin, F; Bunin, N; Johnson, FL; Lenarsky, C; Ohene-Frempong, K; Powars, D; Souillet, G; Sullivan, KM; Vannier, JP; Walters, MC, 1995) |
| "Generalized and partial seizures with secondary generalization were observed during ifosfamide-mesna (IFO) treatment in a patient with lung epidermoid carcinoma." | ( Farisse, P; Somma-Mauvais, H; Viallat, JR, 1994) |
| "Pentylenetetrazole-induced seizure thresholds were similar in mice treated for 14 days with lorazepam or alprazolam, 2 mg/kg/day." | ( Byrnes, JJ; Greenblatt, DJ; Miller, LG; Shader, RI, 1993) |
| "The latency of the audiogenic seizures was prolonged by bromocriptine treatment." | ( Akarsu, ES; Kayaalp, SO; Uzbay, IT, 1994) |
| "Infusions were started 5 min before seizures were induced with flurothyl 3% administered for either 45 (n = 10) or 75 (n = 10) min." | ( Ahdab-Barmada, M; Clyde, C; Kofke, WA; Nemoto, E; Rose, M, 1993) |
| "Reliable clonic seizures were obtained by administering the proconvulsive dopamine D1 agonist SKF 38393 (10 mg/kg i." | ( Alam, AM; Starr, MS, 1994) |
| "The mRNA levels were increased during seizures in the order of c-fos > jun-B > c-jun > jun-D in the hippocampus and jun-B > c-fos > c-jun > jun-D in the cortex, and were increased for a longer duration as well as to a greater extent than after administration of pilocarpine alone." | ( Jope, RS; Williams, MB, 1994) |
| "Despite insignificant changes in seizure latency, chronic pretreatment with CPA increased the incidence of clonic/tonic episodes and end-point mortality." | ( Carter, M; Jacobson, KA; Ji, XD; Paul, IA; Von Lubitz, DK, 1994) |
| "In L-NAME-treated rats, seizure activity occurred about 10 min sooner than in control rats, and status epilepticus was inevitably followed by a flat electroencephalogram and sudden death." | ( Borredon, J; Pinard, E; Rigaud-Monnet, AS; Seylaz, J, 1994) |
| "He had been treated with valproate for seizures since the age of 2 years." | ( Brichard, B; Cornu, G; Ninane, J; Scheiff, JM; Vermylen, C, 1994) |
| "However, seizures associated with clozapine treatment occur at a rate of about three percent." | ( Frankenburg, FR; Toth, P, 1994) |
| "Four patients had generalized seizures only with meperidine administration, all of whom had nonfocal EEG and radiological studies." | ( Ballas, SK; Gzesh, DJ; Liu, JE, 1994) |
| "Ten (5 men, 5 women) had at least one seizure during clozapine treatment." | ( Claussen, AM; Wilson, WH, 1994) |
| "The frequency of spontaneous recurrent seizures was monitored during and after phenobarbital therapy." | ( Chronopoulos, A; Gatt, A; Holmes, GL; Hyde, P; Liu, Z; Mikati, MA; Stafstrom, CE; Thurber, S; Werner, S, 1994) |
| "Two patients developed seizure immediately after flumazenil administration that aimed to reverse the prolonged sedative effect of diazepam." | ( Hseu, SS; Hsing, CH; Lee, TY; Ng, KO; Tang, GJ, 1994) |
| "He had a single grand mal seizure 37 days following retreatment with quinine intravenously, which resulted in rapid clearance of fever and parasitemia, in addition to mefloquine." | ( Aoki, M; Kamei, K; Miyashita, T; Nishiya, H; Ohyatsu, I; Ono, Y; Shibuya, T; Sugiyama, H; Tokumura, Y; Yamaguchi, M, 1994) |
| "The anti-seizure efficacy of intraperitoneally administered anticonvulsants and Ca++ antagonists to CF-1 mice was tested using these models." | ( Cramer, CL; Knowles, MA; Palmer, GC; Stagnitto, ML, 1994) |
| "Phenytoin is frequently used to treat seizure episodes in critically ill patients." | ( Kronfol, NO; Lau, AH, 1994) |
| "Mice selectively bred to be Withdrawal Seizure-Prone (WSP) or Seizure-Resistant (WSR) after chronic ethanol administration have been reported to be differentially sensitive to the anticonvulsant and proconvulsant effects on alcohol withdrawal of drugs interacting with glutamate receptors." | ( Crabbe, J; Dorow, J; Young, ER, 1994) |
| "However, DOPS significantly potentiated seizures induced by imipramine in disulfiram-pretreated animals." | ( Amabeoku, GJ, 1993) |
| "The behavioral pattern of convulsion produced by pentylenetetrazol was similar to that produced by systemic administration of BW373U86." | ( Chang, KJ; Comer, SD; De Costa, BR; Hoenicke, EM; McNutt, RW; Mosberg, HI; Sable, AI; Woods, JH, 1993) |
| "Development of kindled seizures was significantly faster in the intermittently treated group (P < 0." | ( Allerup, P; Barry, DI; Bolwig, TG; Bruhn, T; Glenthøj, B; Hemmingsen, R, 1993) |
| "F-721 was effective against MES seizures following oral administration to mice (ED50: 31." | ( Albertson, T; Drust, EG; Pong, SF; Skeen, GA; Stark, LG; Swinyard, EA; White, HS; Wolf, HH, 1993) |
| "Isolated seizures can be treated with phenytoïne or phenobarbital, while active seizures must be treated with diazepam." | ( Floret, D, 1993) |
| "1S,3R-ACPD-induced seizures were antagonized by systemic administration of dantrolene, an inhibitor of intracellular calcium mobilization, but not by the ionotropic glutamate antagonists MK-801 or GYKI-52466." | ( Fix, AS; McDonald, JW; Schoepp, DD; Tizzano, JP, 1993) |
| "Age, sex, race, seizure type, seizure focus, age at onset, duration of epileptic illness, reasons for discontinuing treatment, other medications, and response to treatment of seizures, psychiatric symptoms, and behavioral symptoms were recorded." | ( Burns, RL; Jenkins, PL; Vallini, AD, 1993) |
| "Meperidine has been associated with seizure activity when administered via traditional routes." | ( Hagmeyer, KO; Mauro, LS; Mauro, VF, 1993) |
| "This case report describes seizures and encephalopathy in a nine year-old boy treated with iodoquinol for amebiasis." | ( Fisher, AK; Szabo, S; Walter, FG, 1993) |
| "Susceptibility to generalized seizures was then tested using the volatile convulsant flurothyl; at both doses of MK801, flurothyl seizure latency was significantly greater in pretreated animals." | ( Holmes, GL; Stafstrom, CE; Thompson, JL, 1993) |
| "In pargyline pretreated GEPR-9s, seizure severity fell and the fraction of animals exhibiting an anticonvulsant response increased progressively as the dose of norepinephrine was increased." | ( Bettendorf, AF; Dailey, JW; Jobe, PC; Kahle, EH; Mishra, PK, 1993) |
| "To report a case of reversible seizures and mental status changes in a dialysis patient given preventive isoniazid therapy." | ( Asnis, DS; Bhat, JG; Melchert, AF, 1993) |
| "Using this novel method of seizure threshold determination, it was found that systemically administered diphenylhydantoin and carbamazepine elevated the threshold for ATPA and had negligible effects on the threshold for kainate and NMDA." | ( Steppuhn, KG; Turski, L, 1993) |
| "Theophylline-induced seizures have significant morbidity and mortality and are difficult to treat." | ( Glenn, GM; Kelly, P; Krober, MS; McCarty, J; Weir, M, 1995) |
| "However, the tonic seizures induced by L-Cysteine were prevented by pretreatment with N(G)-nitro-L-arginine." | ( Yamamoto, H, 1996) |
| "To isolate seizure-related genes, we applied differential screening technique to the cDNA library which constructed from primary cultured cerebral cortical cells treated with pentylenetetrazol (PTZ)." | ( Kajiwara, K; Kimura, M; Nagawawa, H; Ookuri, T; Shimizu-Nishikawa, S; Sugaya, E, 1996) |
| "Acute treatment of breakthrough seizures and clusters of seizures at home with rectal BZDs (usually DZP, 0." | ( Mitchell, WG, 1996) |
| "Epileptic seizures (ES) and nonepileptic seizures (NES) often coexist in patients with treatment-refractory seizures." | ( Alper, K; Devinsky, O; Kothari, M; Luciano, D; Sanchez-Villaseñor, F; Vazquez, B, 1996) |
| "However, the limbic seizures induced by 1 were blocked by systemically administered 2a in a dose-dependent manner (EC50 = 271 mg/kg, ip)." | ( Bond, A; Campbell, JB; Griffey, K; Howe, T; Johnson, BG; Lodge, D; Monn, JA; Paschal, JW; Salhoff, CR; Schoepp, DD; Spangle, LA; Tizzano, JP; Valli, MJ; Wright, RA, 1996) |
| "However, the incidence of seizures induced by potassium cyanide was significantly inhibited by preadministration of melatonin (20 mg/kg, s." | ( Tang, HW; Yamamoto, H, 1996) |
| "Further evaluation of the postictal seizure suppression immediately after a fully kindled seizure demonstrated that morphine-pretreated rats had a decreased sensitivity to subsequent kindling stimulations." | ( Ackermann, RF; Engel, J; Rocha, L, 1996) |
| "A similar increase in seizure prevalence, noted as a kindling effect, was observed in cocaethylene-treated animals tested with cocaethylene in that 90% of the mice exhibited status epilepticus on the last test day." | ( Meehan, SM; Schechter, MD, 1996) |
| "Rotational behavior and convulsions were prevented by intrastriatal preadministration of MK-801 and attenuated by preadministration of succinate." | ( Begnini, J; da Costa, E; de Bastiani, J; de Mello, CF; Jiménez-Bernal, RE; Rubin, MA; Wajner, M, 1996) |
| "The treatment had no effect on the seizure threshold for picrotoxin." | ( Chiu, TH; Rosenberg, HC; Zhao, TJ, 1996) |
| "Cocaine use can reduce seizure threshold in patients with underlying epilepsy as a direct toxic effect or indirectly by contributing to poor compliance with antiepileptic drug treatment, poor diet, or poor sleep habits." | ( Daras, M; Koppel, BS; Samkoff, L, 1996) |
| "In all seizure paradigms, KYNA levels in the dialysate began to rise within 1 h and gradually reached a plateau approximately 4 h after administration of the convulsants." | ( Schwarcz, R; Wu, HQ, 1996) |
| "L-NA (100 mg/kg, IP) suppressed clonic seizure as well as tonic seizure in bicuculline-treated (3." | ( Endo, T; Hara, S; Iwata, N; Kano, S; Kuriiwa, F; Mukai, T, 1996) |
| "Subjects with a seizure history were prophylactically treated with tapering doses of chlordiazepoxide." | ( Worner, TM, 1996) |
| "During medical treatment, symptomatic seizures occurred in three cases." | ( Hashi, K; Niwa, J; Tanabe, S, 1996) |
| "Starting vigabatrin treatment reduced seizure frequency by > 50%, from six to seven per month to three." | ( Behar, KL; Mattson, RH; Petroff, OA; Rothman, DL, 1996) |
| "The increase in seizure severity was evidenced by a significant increase in the incidence of tonic convulsions in 5,7-DHT treated animals (53% in treated animals compared to 0% in vehicle treated controls) over the testing period." | ( Browning, RA; Clough, RW; Dailey, JW; Jobe, PC; Maring-Smith, ML; Statnick, MA; Wang, C, 1996) |
| "However, other side effects of seizures, sedation, neuroleptic malignant syndrome and cardiovascular, hematologic, endocrinological, and weight gain problems remain as clinical management challenges posed by existing antipsychotic drug therapy." | ( Casey, DE, 1996) |
| "Audiogenic seizures could be induced in all treatment groups 12 h after withdrawal." | ( Davidson, M; Matsumoto, I; Otsuki, M; Wilce, PA, 1996) |
| "Treatment was dictated by the cat's seizure frequency and by the underlying cause." | ( McDonell, W; Parent, JM; Quesnel, AD, 1997) |
| "Results suggest that severity of seizure disorder in cats is not a good predictor of outcome and that aggressive treatment is often rewarding, even in the most severe cases." | ( McDonell, W; Parent, JM; Quesnel, AD, 1997) |
| "On the other hand, no difference in seizure susceptibility was found between homozygous and heterozygous mutants when strychnine was administered." | ( Miyakawa, T; Niki, H; Tateishi, K; Yagi, T, 1996) |
| "A saline-treated group gave a 100% seizures response, while the group treated with NR1 antisense probe gave a 7% seizure response to the sound stimulus." | ( Chapman, AG; Meldrum, BS; Woodburn, VL; Woodruff, GN, 1996) |
| "In one patient with intractable seizures, the therapy was not effective." | ( Aihara, M; Hatakeyama, K; Hinohara, Y; Kamiya, Y; Kanemura, H; Nakazawa, S; Sata, Y; Shimoda, C, 1997) |
| "Nicardipine remarkably inhibited epileptic seizures induced by combined treatment with enoxacin (p." | ( Kamei, C; Kitazumi, K; Ohishi, H; Okumura, Y; Sugimoto, Y, 1996) |
| "Limbic seizures were provoked in freely moving rats by intrahippocampal administration of the muscarinic receptor agonist pilocarpine via a microdialysis probe (10 mM for 40 min at 2 microliters/min)." | ( Ebinger, G; Michotte, Y; Smolders, I; Van Belle, K, 1997) |
| "Furthermore, seizure latencies after the administration of an ED100 dose of NMDA (150 mg/kg) were significantly higher in antisense treated animals compared to vehicle controls." | ( Adan, J; Capdevila, JL; Martínez, JM; Piulats, J; Tarrason, G; Trullas, R; Zapata, A, 1997) |
| "In adults without a seizure history, seizures were observed only in patients treated with high dose chlorambucil; however, in adults with a seizure history, lower doses as used in pulse therapy also caused seizures." | ( Cooper, DL; Khan, KK; Salloum, E, 1997) |
| "Intrastriatal injection of ET-1 caused seizures and barrel rolling which were prevented by pretreatment with the N-methyl-D-aspartate (NMDA) receptor antagonist MK-801 and attenuated by the nitric-oxide synthase inhibitor N omega-nitro-L-arginine (L-NNA)." | ( Morton, AJ; Reynolds, DS; Sullivan, AM; Thomas, KL, 1996) |
| "Pretreatment with diazepam blocked the seizures as well as the elevation of BDNF mRNA." | ( Gall, CM; Kornblum, HI; Sankar, R; Shin, DH; Wasterlain, CG, 1997) |
| "To compare treatment of ongoing seizures using intramuscular (IM) midazolam versus intravenous (IV) diazepam." | ( Altieri, MA; Chamberlain, JM; Futterman, C; Ochsenschlager, DW; Waisman, Y; Young, GM, 1997) |
| "The decrease in the seizure threshold for pentylenetetrazole during diazepam withdrawal was inhibited by pretreatment with MK-801 ((+)-5-methyl-10,11-dihydro-5H-dibenzo(a,d)cycloheptan-5,10-imine maleate), 7-chlorokynurenic acid and ifenprodil." | ( Misawa, M; Suzuki, T; Tsuda, M, 1997) |
| "Generalized tonic-clonic seizures observed in EP mice were inhibited by valproate, administered 1 h prior to testing, in a dose-response fashion." | ( Alexiuk, NA; Vriend, JP, 1996) |
| "The overall frequency of seizures during muromonab-CD3 administration is 6%." | ( Lawrence, KR; Monaco, AP; Rahamtulla, AF; Seifeldin, RA, 1997) |
| "The incidence of seizures in rats receiving cocaine or lidocaine individually was significantly reduced by pre-treatment with dextromethorphan but not DNQX." | ( Abdel-Rahman, MS; Barat, SA, 1997) |
| "Propofol consistently reduces the seizure duration during electroconvulsive therapy, its use has been successful in controlling refractory status epilepticus and in animals it offers a strong protection against lignocaine- or pentylene-tetrazol-induced epilepsy." | ( Borgeat, A, 1997) |
| "One patient experienced a seizure immediately after administration of naloxone." | ( Anderson, DL; Benson, BE; Gorman, SE; Ruskosky, DR; Spiller, HA; Stancavage, MM; Villalobos, D, 1997) |
| "Opinions vary as to which 'neonatal seizures' should be treated and which should not be." | ( Caballar-Gonzaga, FJ; Dierkes, T; Koenigsberger, MR, 1997) |
| "Two patients died following seizures, but three patients recovered following prompt treatment with parenteral midazolam infusions and rotation to alternative opioids." | ( Hagen, N; Swanson, R, 1997) |
| "I report the occurrence of seizure activity after the inadvertent administration of 4 mg/kg of tramadol to a child." | ( Tobias, JD, 1997) |
| "In rats susceptible to audiogenic seizures, intraperitoneal administration of both GABAB receptor antagonists, at doses which suppressed absence seizures, facilitated the elicitation of sound-induced tonic seizures." | ( Bernasconi, R; Boehrer, A; Marescaux, C; Simler, S; Vergnes, M, 1997) |
| "The phrase alcohol withdrawal seizures (AWS) refers to seizures that result from the withdrawal of alcohol after a period of chronic alcohol administration." | ( Tan, CY; Weaver, DF, 1997) |
| "After initiation of therapy, seizures resolved after 2." | ( Bai, AN; Cao, YM; Chui, W; Gao, DY; Ge, ZL; Jiao, FY; Li, HR; Lieu, NS; Liu, SB; Liu, ZY; Takuma, Y; Wu, S; Zhang, XK, 1997) |
| "However, the seizure-producing dose of cocaine was decreased dose dependently in rats that received naltrindole, regardless of the route of administration, naloxone, or naltrexone." | ( Gordon, FJ; Holtzman, SG; Patterson, AB, 1997) |
| "(2) Neurophysiologically, the increased seizure susceptibility to pentylenetetrazol treatment reached a maximum at four days post-trimethyltin and then declined after five days post-trimethyltin." | ( Akaike, M; Ishida, N; Kanai, H; Kato, N; Kuroda, Y; Masui, A; McEwen, BS; Sadamatsu, M; Tsutsumi, S; Watanabe, Y, 1997) |
| "Although seizures may be a feature of the disease being treated, antibiotics should be considered possible causes of seizures, particularly if suggested by temporal relationships between seizure activity and drug administration." | ( Wallace, KL, 1997) |
| "rats with a pentylenetetrazole-induced seizure score of 3 or more on a seizure scale ranging from 0 to 6) and death rate compared with those obtained for rats pre-treated with an equivalent intraperitoneal dose (140 mg kg-1) of acepifylline ('equivalent dose' referred to here denotes the theophylline content of the two preparations)." | ( Chakrabarti, A; Garg, SK; Saini, HK, 1997) |
| "This treatment controlled seizures in 86% of patients (49/57), on average within 40 minutes (median, 30 min; range, 10-120 min), at a mean infusion rate of 0." | ( Banerjee, S; Singhi, P; Singhi, S, 1998) |
| "The lidocaine levels at seizure threshold were increased in the propofol-treated rats: 16." | ( DiFazio, CA; Lee, VC; Moscicki, JC, 1998) |
| "The potential for convulsions induced by the coadministration of ciprofloxacin (CPFX) and foscarnet (PFA) may be due not to a change in the distribution of CPFX to the brain but to a potential CPFX-induced inhibition of gamma-aminobutyric acid (GABA)-GABA(A) receptor binding in the presence of PFA." | ( Iga, T; Kawakami, JI; Matsuo, H; Nagata, A; Ryu, M; Sawada, Y; Uchida, T; Yamamoto, K, 1998) |
| "Pentylenetetrazol (PTZ) seizure threshold was determined in the rat during recovery from anesthesia induced by intravenous administration of propofol (20 mg/kg) or thiopentone (30 mg/kg)." | ( Hasan, Z, 1997) |
| "The increase in seizure sensitivity of repeatedly withdrawn mice was prevented by treatment with the NMDA receptor antagonist CGP 39551 (20 mg/kg, i." | ( Dunworth, SJ; Stephens, DN, 1998) |
| "Drug-induced exacerbation of seizures is a serious and common clinical problem that is often unrecognized or overlooked by the treating physician." | ( Avanzini, G; Dulac, O; Gram, L; Perucca, E, 1998) |
| "The suppression of the convulsions by 7-nitroindazole was not reversed by the pretreatment of L-arginine." | ( Masukawa, T; Nakanishi, K; Natsuki, R, 1998) |
| "One child presented with a seizure and cortical venous drainage that were treated immediately." | ( Balousek, PA; Ciricillo, SF; Dowd, CF; Edwards, MS; Halbach, VV; Higashida, RT, 1998) |
| "These results show that tonic or tonic-clonic seizures induced by TMPP administration (0." | ( Jung, AE; Lindsey, JW; Narayanan, TK; Ritchie, GD, 1998) |
| "long-term occurrence of spontaneous, generalized seizures and motor convulsions) following a latent period after the initial treatment." | ( Buckmaster, PS; Dudek, FE; Hellier, JL; Patrylo, PR, 1998) |
| "A case of tonic-clonic seizures following chloroquine treatment for leprosy reactions in a Nigerian male is reported." | ( Ebenso, BE, 1998) |
| "To do so, the maximal electroshock seizure test in mice (an experimental model predicting drug efficacy in the treatment of human generalized tonic-clonic seizures) was employed to (1) quantify changes in the protective efficacy and potency of felbamate produced by adjunct drugs and (2) assess the ability of aminophylline and caffeine to affect protective efficacy afforded by a submaximal protective dose of felbamate against maximal electroshock-induced seizures." | ( Borowicz, K; Czuczwar, SJ; Gasior, M; Kleinrok, Z; Przybyłko, M; Swiader, M; Turski, WA, 1998) |
| "During the first 4 weeks of therapy seizure recurrence was seen in 9." | ( Baranwal, AK; Khandelwal, N; Singhi, PD; Singhi, SC, 1998) |
| "Audiogenic seizures caused a marked induction of c-fos messenger RNA (mRNA) in septal nucleus, bed nucleus of stria terminalis, amygdaloid nuclei, peripeduncular nucleus, and inferior colliculus, which was almost completely blocked by the pretreatment with MK-801." | ( Higashiyama, A; Ishida, N; Kato, N; Kuroda, Y; McEwen, BS; Nishimura, T; Yasuda, S, 1998) |
| "Successful treatment of seizure disorders in small animals requires proper patient assessment, understanding the principles of antiepileptic drug (AED) therapy, designing a strategy for pharmacotherapy, and plans for emergency treatment." | ( Podell, M, 1998) |
| "The clonic convulsions were not modified by MgCl2 treatment." | ( Lazarini, CA; Vassilieff, I, 1998) |
| "Chemically kindled clonic seizures were observed in 100% of TMPP or FG-7142 and 50% of PTZ treated rats by the thirtieth dosing." | ( Cassell, J; Lin, J; Nordholm, AF; Ritchie, GD; Rossi, J, 1998) |
| "Diastat treatment reduced median seizure frequency (p = 0." | ( Cereghino, JJ; Kriel, RL; Mitchell, WG; Murphy, J; Rosenfeld, WE; Trevathan, E, 1998) |
| "We describe four infants whose seizures were treated with intravenous fosphenytoin." | ( Caviness, VS; Krishnamoorthy, KS; Soman, TB; Takeoka, M, 1998) |
| "Treatment was with anti-seizure, anti-viral, and immunomodulating medication." | ( Stübgen, JP, 1998) |
| "These audiogenic seizures were differently modified by MK-801 and NBQX; while intraperitoneal MK-801 equally inhibited running fit (RF) and generalized tonic-clonic seizure (GTCS), NBQX administered into cisterna ambiens significantly inhibited RF but not GTCS." | ( Higashiyama, A; Ishida, N; Kato, N; Yasuda, S, 1998) |
| "Dizocilpine alone had no effect on seizure induction and did not potentiate the anticonvulsive effect of lorazepam when coadministered with lorazepam." | ( Fahey, JM; Greenblatt, DJ; Pratt, JS; Pritchard, GA; Shader, RI, 1999) |
| "Because of the convulsions, the treatment was discontinued." | ( Bouvy, M; Heeringa, M; Kuster, JA; Meyboom, RH, 1998) |
| "Continuous seizures of more than 5 min duration were randomly treated with buccal midazolam or rectal diazepam." | ( Besag, FM; Neville, BG; Scott, RC, 1999) |
| "Buccal midazolam was used to treat 40 seizures in 14 students, and rectal diazepam 39 seizures in 14 students." | ( Besag, FM; Neville, BG; Scott, RC, 1999) |
| "All children who presented in a convulsion, including convulsive status epilepticus, to the accident and emergency department over a 12-month period and who required treatment, were reviewed retrospectively to identify the effectiveness and safety of a specific treatment protocol." | ( Appleton, RE; Garr, RE; Molyneux, EM; Robson, WJ, 1999) |
| "A newborn infant with seizures of unknown etiology that were refractory to treatment with phenobarbitone, phenytoin, midazolam, clonazepam, and vigabatrin is reported." | ( Antony, JH; Barr, PA; Buettiker, VE, 1999) |
| "The most important factor determining seizure recurrence was continued therapy, which was the case for barbiturates, phenytoin and valproate." | ( Chadwick, D, 1999) |
| "Drug-induced seizures have occurred and will continue to occur as healthcare professionals exceed recommended dosing guidelines to treat critically ill patients." | ( Hunter, WJ, 1993) |
| "Furthermore, the latency of convulsions in mice induced by administration of theophylline at a higher dose (240 mg/kg, i." | ( Chisaki, K; Hayashi, H; Komatsu, Y; Sanae, F, 1999) |
| "By measuring the latency to generalized seizures after beta-CCM administration to A/J and C57BL6/J mice and their progeny, we estimated a heritability of 0." | ( Gershenfeld, HK; Li, X; Neumann, PE; Paul, SM; St Jean, PL, 1999) |
| "administration in relief of seizures, e." | ( Bechgaard, E; Gizurarson, S; Gudbrandsson, FK; Jónsson, H, 1999) |
| "All 30 of the control mice had seizures followed by death compared to 11 seizures and 7deaths in the 15 treatment mice." | ( Brubacher, JR; Hoffman, RS; Lachmanen, D; Ravikumar, PR, 1999) |
| "Isoniazid-induced seizures respond poorly to anticonvulsants but well to pyridoxine (Vitamin B6); theophylline produces difficult-to-treat seizures with substantial morbidity and mortality." | ( Bonner, AB; Peterson, SL; Weir, MR, 1999) |
| "Rats presenting partial seizures showed no alterations in the immunostaining pattern compared with saline-treated animals." | ( Cavalheiro, EA; Funke, MG; Naffah-Mazzacoratti, MG; Sanabria, ER, 1999) |
| "Neonates whose seizures were not controlled by the assigned drug were then treated with both drugs." | ( Alvin, J; Armatti, S; Gardiner, JC; Minnigh, B; Painter, MJ; Paneth, N; Scher, MS; Stein, AD; Wang, Z, 1999) |
| "When combined treatment is considered, seizure control was achieved in 17 (57 percent) of the neonates assigned to receive phenobarbital first and 18 (62 percent) of those assigned to receive phenytoin first (P=0." | ( Alvin, J; Armatti, S; Gardiner, JC; Minnigh, B; Painter, MJ; Paneth, N; Scher, MS; Stein, AD; Wang, Z, 1999) |
| "Compounds 4a,b and 5a-c antagonize seizures induced by AMPA and kainate (KA) and their anticonvulsant activity is reversed by pretreatment with aniracetam." | ( Baraldi, M; De Micheli, C; De Sarro, A; De Sarro, G; Grasso, S; Micale, N; Puia, G; Zappalà, M, 1999) |
| "Electroconvulsive shock (ECS) seizures provide an animal analog of electroconvulsive therapy (ECT)." | ( Burnham, WM; Cottrell, GA; Gombos, Z; Mendonça, A, 1999) |
| "Medical records were reviewed for seizure and medication history, diagnostic test results, types of treatment, hospitalization costs, and outcome of hospital visits." | ( Bateman, SW; Parent, JM, 1999) |
| "The authors believe that diencephalic seizures can present with a spectrum of autonomic features, and treatment should be tailored with the appropriate pharmacologic blockade." | ( Conway, EJ; DaRosso, RC; Epstein, FJ; Goh, KY; Muszynski, CA, 1999) |
| "In saline-treated controls, hypoxic seizures were most frequent at 15 days (80% of pups) and 20 days (60%) of age." | ( Allred, E; Holtzman, D; Jensen, F; Khait, I; Kraft, R; Mulkern, R; Rand, T, 1999) |
| "In contrast to the seizure activity and wide-spread neuronal degeneration following kainate treatment, injections of lidocaine did not produce neuronal death within three days." | ( Chae, HJ; Cho, SB; Gwag, BJ; Jin, BG; Kang, JS; Kim, HR; Won, SJ, 1999) |
| "Interestingly, convulsions which were observed in the NMDA-treated rats were almost totally suppressed by bilobalide." | ( Chatterjee, SS; Hilgert, M; Klein, J; Lehr, M; Weichel, O, 1999) |
| "Vigabatrin improves seizure control as add-on therapy for refractory partial seizures and may produce therapeutic benefits in the treatment of infantile spasms." | ( Gidal, BE; Gilman, JT; Privitera, MD; Sheth, RD, 1999) |
| "All animals developed seizures following this treatment." | ( Copeland, T; McDonough, JH; McMonagle, J; Shih, TM; Zoeffel, D, 1999) |
| "Sensitivity to PTZ-induced seizures and lethality was not affected in mice with a history of repeated treatment with ganaxolone, diazepam, or valproate." | ( Beekman, M; Carter, RB; Gasior, M; Ungard, JT; Witkin, JM, 2000) |
| "Cocaine-induced convulsions were observed following pretreatment with various doses of the following 5-HT(2) antagonists: mianserin, metergoline, MDL 11939, and methiothepin." | ( George, FR; Kreifeldt, MJ; O'Dell, LE; Ritz, MC, 2000) |
| "PD 123319 did not change the seizure threshold both in theophylline-untreated and -treated mice." | ( Georgiev, V; Kambourova, T; Tchekalarova, J, 2000) |
| "Potentiation of convulsions by BSO treatment was recovered by supplying GSH (10 nmol, i." | ( Abe, K; Nakanishi, K; Saito, H, 2000) |
| "We report convulsions induced by short-term metronidazole therapy used in conventional doses for Clostridium difficile colitis in an elderly patient with chronic renal failure." | ( Beloosesky, Y; Grinblat, J; Grosman, B; Marmelstein, V, 2000) |
| "It is noteworthy that the antiseizure potency of the combined treatment (diazepam 1." | ( Borowicz, KK; Czuczwar, SJ; Kleinrok, Z, 2000) |
| "Bupivacaine seizure doses in 7-NI and L-NAME pretreated animals were similar to control but significantly different from each other." | ( Heavner, JE; Shi, B, 2000) |
| "Sound induced convulsions in DBA/2 mice were dose-dependently inhibited by all compounds (administered intraperitoneal, i." | ( Dalby, NO, 2000) |
| "To study the seizure-induced activation of glutamate decarboxylase, we investigated the expression of both embryonic and adult glutamate decarboxylase messenger RNAs in the adult rat hippocampus after kainic acid administration by semi-quantitative reverse transcription-coupled polymerase chain reaction, in situ hybridization and immunoblotting." | ( Hoertnagl, B; Kartarova, Z; Somogyi, R; Sperk, G; Szabó, G, 2000) |
| "The tonic convulsions appeared 5-6 h after MSO administration, without brain glycogen content variations during the preconvulsive period." | ( Ardourel, M; Bernard-Helary, K; Cloix, JF; Hévor, T; Lapouble, E, 2000) |
| "Treatment with oral L-serine abolished seizures and improved psychomotor development, hyperexcitability, head growth, cortical and subcortical hypotrophy, and hypomyelination of the brain on MRI scans." | ( Aracil, A; Artuch, R; García González, MM; Jaeken, J; Pineda, M; Santos, S; Van Schaftingen, E; Vilaseca, MA, 2000) |
| "A significant decrease in seizure susceptibility could be observed in BCCA treated mice compared with sham-operated controls." | ( Kleinrok, Z; Rejdak, K; Rejdak, R; Sieklucka-Dziuba, M, 2000) |
| "Most children with symptoms of convulsions are taken to the health center, but are more likely than children with simple malaria to receive traditional treatments as well." | ( Baume, C; Helitzer, D; Kachur, SP, 2000) |
| "In one dog, seizures kept recurring after periods of successful control following administration of propofol." | ( Grasmueck, S; Steffen, F, 2000) |
| "However, the attenuation of severe seizures by a single PRA, PHEN, DZP, or PHB cotreatment was accompanied by a decrease in the brain COCA concentration." | ( Fukui, Y; Hayase, T; Yamamoto, K; Yamamoto, Y, 2000) |
| "ICV administered DHEAS induced seizures in a dose-dependent way." | ( Bidziński, A; Członkowska, AI; Krzaścik, P; Płaźnik, A; Siemiatkowski, M; Sienkiewicz-Jarosz, H; Szyndler, J, 2000) |
| "The authors reviewed the occurrence of seizures in patients with epilepsy who had all their antiepileptic medications discontinued during an 8-week period, converted to gabapentin monotherapy, and observed for 26 weeks as part of the gabapentin trial #945-082." | ( DeToledo, JC; Garofalo, EA; Greiner, M; Lowe, MR; Ramsay, RE, 2000) |
| "In a general population, risk of seizure may be associated with long-term therapy with tramadol or the presence of cofactors, or confined to a small sensitive population subset." | ( Alderfer, R; Anderson, G; Blough, D; Drinkard, CR; Gardner, JS; Graham, D; Shatin, D, 2000) |
| "Animals which developed seizures were treated for 3 days with rofecoxib (10 mg/kg, i." | ( Kunz, T; Oliw, EH, 2001) |
| "To report development of a seizure after administration of ropivacaine." | ( Alardo, JP; Bisschop, DY; Germain, ML; Just, BY; Millart, HG; Razgallah, B; Trenque, TC, 2001) |
| "High rate of seizure recurrence mandates therapy of solitary seizure in patients with HIV infection." | ( Chadha, DS; Handa, A; Sharma, SK; Singh, AP; Varadarajulu, P, 2000) |
| "However, the increase in convulsion thresholds and lethal doses was much greater for GABAergic antagonists (PIC, BIC, and PTZ) than non-GABAergic convulsants (STY, 4AP, and NMDA) following 2000 mg/kg TCE administration." | ( Chen, HH; Chiu, TH; Shih, CL, 2001) |
| "We experienced a case of convulsion following the combination of single oral administration of enoxacine before an emergency operation and single postoperative intravenous administration of flurbiprofen axetil." | ( Kaneko, A; Machida, K; Mizuno, J; Sugimoto, S; Tsutsui, T; Zushi, N, 2001) |
| "The drug significantly reduced seizure frequency compared with placebo in children with partial-onset epilepsy after 16 weeks of double-blind adjunctive treatment (33." | ( McClellan, K; Ormrod, D, 2001) |
| "VNS effectively reduced seizure severity in both capsaicin- and vehicle-treated rats as compared with their non-VNS baselines." | ( Handforth, A; Krahl, SE; Senanayake, SS, 2001) |
| "She presented repetitive generalized convulsions with metabolic acidosis, treated with diazepam and 7." | ( Hamabe, Y; Kiyota, K, 2001) |
| "MP administration (150 mg/kg, i." | ( Giraldez, L; Girardi, E; Rodríguez de Lores Arnaiz, G; Vanore, G, 2001) |
| "All rats had stage 5 convulsions 24 hr after cessation of the administration of dipotassium clorazepate and diazepam." | ( Amano, K; Deshimaru, M; Katsuragi, S; Miyakawa, T; Miyazaki, C; Ogata, A; Takamatsu, J, 2001) |
| "Six dogs with partial seizures or partial seizure-like activity were treated with the antiepileptic drug felbamate between 1993 and 1998." | ( March, P; Podell, M; Ruehlmann, D, 2001) |
| "Phenylephrine increased seizure duration in ECS-treated rats, and also enhanced recall in both true and sham ECS groups." | ( Anand, A; Andrade, C; Guido, S; Sudha, S; Venkataraman, BV, 2001) |
| "We describe a prolonged seizure occurring during the first treatment of a course of ECT in an adult patient receiving long-term bupropion therapy, lithium, and venlafaxine." | ( Conway, CR; Nelson, LA, 2001) |
| "Furthermore, seizure activity on kainic acid administration was markedly increased in mutant mice and was accompanied by heightened immediate early gene (c-fos) expression throughout the brain." | ( Davies, B; Davies, CH; Kearns, IR; Lathe, R; Ure, J, 2001) |
| "The interval until convulsion due to picrotoxin was also prolonged by the administration of DMP combined with diazepam and valproic acid (VPA)." | ( Aoyagi, Y; Ohta, A; Watanabe, Y; Yamada, K, 2001) |
| "Sixteen patients with pharmacoresistant partial seizures undergoing presurgical evaluation were randomized in this double-blind, placebo-controlled, parallel-group Losigamone monotherapy study under continuous video-EEG monitoring." | ( Dienel, A; Feichtinger, M; Hopp, P; Kerling, F; Kirchner, A; Pauli, E; Stefan, H; Wang, Y; Zhou, D, 2001) |
| "To report two cases of seizures following administration of levofoxacin and ciprofloxacin." | ( Kushner, JM; Peckman, HJ; Snyder, CR, 2001) |
| "As generalized seizures such as absence and myoclonus were counted in only one trial, results do not address the treatment of these seizure types." | ( Marson, AG; Tudur Smith, C; Williamson, PR, 2001) |
| "During limbic status epilepticus, only seizures in the sensorimotor cortex were markedly attenuated a few minutes after 14C-ZNS administration." | ( Akaike, K; Fukumoto, S; Imamura, S; Takigawa, M; Tanaka, S; Tojo, H, 2001) |
| "To provide data on the incidence of seizures and response to anticonvulsant therapies, a cohort of 90 term infants with hypoxic-ischemic encephalopathy treated at our institution between January 1, 1995, and July 1, 1999, was reviewed." | ( Armstrong, DL; Battin, MR, 2001) |
| "Control had initial "drop-off" seizure burst rates over time; seizure bursts in the treatment groups were compared to these rates." | ( Engebretsen, KM; Harris, CR; Holger, JS, 2002) |
| "Rate of seizure occurrence after initial treatment was higher in infants with cortical hypometabolism on the second PET, but the difference was not statistically significant." | ( Ishigaki, T; Itomi, K; Natsume, J; Negoro, T; Okumura, A; Tadokoro, M; Takada, H; Watanabe, K, 2002) |
| "These seizures were completely abolished by the simultaneous administration of melatonin (20 mg/kg, ip), a potent scavenger of hydroxyl radical." | ( Mohanan, PV; Yamamoto, HA, 2002) |
| "The reduced seizure threshold confirm the modulatory role exerted by progesterone on central nervous system excitability, and may be relevant in epileptic patients undergoing antifungal therapy." | ( Acevedo, X; Bustamante, D; Miranda, HF; Pesce, ME; Pinardi, G, 2001) |
| "Furthermore, brain seizure activity recorded following 1 h MCAo and 72 h of recovery in injured rats was either completely blocked (30 min pre-MCAo treatment) or significantly reduced (30 min post-MCAo treatment) with RS100642 (1." | ( Tortella, FC; Williams, AJ, 2002) |
| "Recurrent seizures were treated with diazepam and broad complex tachycardia was successfully treated with adenosine." | ( Ali, I; Casey, PB; Cassidy, N; Tracey, JA, 2002) |
| "Clinical seizures after venlafaxine treatment have occasionally been reported when the drug was used at very high doses or in combination with other medications." | ( Agustine, PE; Do Monte, FH; Lanziotti, VM; Russi, M; Santos, JG, 2002) |
| "Propofol anesthesia increases the seizure threshold of patients receiving electroconvulsive therapy." | ( Nishihara, F; Saito, S, 2002) |
| "In the other 10 babies electrographic seizures increased after treatment, whereas electroclinical seizures reduced." | ( Binnie, CD; Boylan, GB; Morton, M; Pressler, RM; Rennie, JM; Wilson, G, 2002) |
| "Here, we report a case who sustained convulsion immediately after administration of epidural ropivacaine." | ( Cherng, CH; Ho, ST; Wong, CS, 2002) |
| "Higher prevalence of seizures in large dogs, compared with smaller dogs, may be caused by administration of larger total volumes of contrast agent per volume of CSF." | ( Barone, G; Shofer, FS; Steinberg, SA; Ziemer, LS, 2002) |
| "Specifically, seizure induction by KA injection into the amygdala induces tPA activity and cell death in both hippocampi, and unilateral treatment of rats with neuroserpin, a natural inhibitor of tPA in the brain, enhances neuronal survival in both hippocampi." | ( Bugge, TH; Coleman, TA; Lawrence, DA; Mitola, D; Moore, E; Sandkvist, M; Wu, JY; Yepes, M, 2002) |
| "Seventy three patients presenting with seizures and showing SSECTL on cranial CT scans (plain and contrast) were randomized into group A (6 months therapy) and group B (2 years therapy)." | ( Arora, A; Lal, V; Prabhakar, S; Sawhney, IM; Thussu, A, 2002) |
| "A pentylenetetrazole seizure test was administered 15 min after the injections." | ( Burnham, WM; Likhodii, SS, 2002) |
| "The thresholds for the clonic seizures induced after intravenous administration of pentylenetetrazole (PTZ) or bicuculline were assessed in mice weighing 23-30 g." | ( Dehpour, AR; Homayoun, H; Khavandgar, S, 2002) |
| "In another experiment, WDS and seizures were monitored after KA treatment alone or in combination with L-NA." | ( Koylu, EO; Manev, H; Pogun, S; Uz, T, 2002) |
| "Of the 56 seizures treated, 30 received lorazepam, 19 diazepam, and seven both drugs." | ( Dooley, JM; Harrison, R; Stewart, WA, 2002) |
| "Furthermore, it antagonized in vivo seizures induced by icv administration of AMPA or kainate (KA)." | ( De Micheli, C; De Sarro, A; De Sarro, G; Ferreri, G; Grasso, S; Micale, N; Puja, G; Toma, L; Zappalà, M, 2002) |
| "Cocaine kindled seizures were developed in male, Swiss-Webster mice by daily administration of 60 mg/kg cocaine for 5 days." | ( Gasior, M; Hartman, T; Schad, C; Shippenberg, T; Slusher, BS; Witkin, JM; Zapata, A, 2002) |
| "Cefoselis (50 microg/animal)-induced convulsions were prevented by pretreatment with 5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine (MK-801), diazepam and phenobarbital (ED(50) values (mg/kg) of 0." | ( Matsuoka, N; Mochizuki, Y; Mutoh, S; Sugimoto, M; Terai, T; Uchida, I; Yamazaki, S, 2002) |
| "Neurotoxicity manifesting as convulsions is a recognised complication of the administration of local anaesthetic drugs as part of a regional anaesthetic technique." | ( Pirotta, D; Sprigge, J, 2002) |
| "To determine the risk of seizure recurrence after a first seizure due to neurocysticercosis (NC) and to evaluate risk factors for seizure recurrence, including the influence of antihelminthic treatment." | ( Carpio, A; Hauser, WA, 2002) |
| "Gastrodin reduced the seizure score in the treated group, although the immunoreactivities of GABA synthetic enzymes and GABA transporters were unaltered in gastrodin-treated animals." | ( An, SJ; Baek, NI; Choi, SY; Hwang, IK; Jung, SJ; Kang, TC; Kim, SK; Kwon, OS; Lee, HY; Park, SK; Won, MH, 2003) |
| "GM1 pretreatment decreased MMA-induced convulsions (GM1-MMA: 6." | ( Bonini, JS; de Oliveira, TG; Dutra-Filho, CS; Fighera, MR; Frussa-Filho, R; Mello, CF; Rocha, JB; Rubin, MA, 2003) |
| "This subset experiences more seizures prior to the initiation of treatment, is more likely to be treated initially with a noncarbamazepine medication, and tends to have a higher frequency of associated conditions." | ( Al-Twajri, WA; Shevell, MI, 2002) |
| "Overall, 59% of the animals had seizures terminated within 30 min of the biperiden administration." | ( Byers, CE; Capacio, BR; Caro, ST; McDonough, JH, 2003) |
| "Whether better control of neonatal seizures leads to a reduction in neurodisability in childhood cannot be determined until more effective treatments are found." | ( Boylan, GB; Rennie, JM, 2003) |
| "Moreover, seizure duration was not dependent on the time of ECT administration in the time window between one and 6 minutes after loss of consciousness." | ( Brock-Utne, JG; Debattista, C; Lemmens, HJ; Levi, DC, 2003) |
| "To report a seizure occurring secondary to meperidine treatment despite normal renal and central nervous system (CNS) function, and to provide a review of meperidine's role in pain management, including its use in pancreatitis and sphincter of Oddi dysfunction." | ( Hubbard, GP; Wolfe, KR, 2003) |
| "Five minutes after the start of EEG seizures, animals were treated im with different doses of anticholinergics or benzodiazepines and observed for seizure termination." | ( Duniho, SM; McDonough, JH; Shih, TM, 2003) |
| "Garenoxacin did not induce any convulsions at intravenous doses up to 60 mg/kg in combination with 200 mg/kg oral administration of fenbufen in mice, and its convulsant activity was weaker than those of enoxacin, norfloxacin, ciprofloxacin, alatrofloxacin and ofloxacin." | ( Fukuda, H; Kawamura, Y; Morita, Y; Nakamura, T; Soumi, K, 2003) |
| "We report a case of postpartum convulsions due to a benign cerebral angiopathy occurring after bromocriptine therapy to suppress lactation." | ( Burckard, E; Combourieu, E; Escarment, J; Felten, D; Patrigeon, RG, 2003) |
| "Guanosine prevented seizures in 40% and death in 50% on mice treated with i." | ( Elisabetsky, E; Frizzo, ME; Izquierdo, I; Schmidt, AP; Souza, DO; Vinadé, ER, 2003) |
| "Nicotine-induced seizures were blocked by cotreatment with either the nonselective antagonist mecamylamine or the alpha7*-selective antagonist methyllycaconitine." | ( Collins, AC; Dobelis, P; Hutton, S; Lu, Y, 2003) |
| "The antiseizure potency of the ketamine/carbamazepine combination was comparable to that of carbamazepine alone administered at 20 mg/kg, while the effect of ketamine/valproate was comparable to the efficacy of valproate alone at 100 mg/kg." | ( Borowicz, KK; Czuczwar, SJ, 2003) |
| "Treatment of seizures in pediatric patients is complicated by the fact that the etiology of the disorder and the pharmacokinetics, efficacy, and safety of antiepileptic drugs (AEDs) may differ from that in adults." | ( Dulac, O; Glauser, TA, 2003) |
| "Patients who achieved adequate seizure control with levetiracetam as add-on therapy in a double-blind, placebo-controlled study entered a monotherapy phase of the trial in which the baseline AED was gradually withdrawn." | ( Ben-Menachem, E, 2003) |
| "The proportion of children who had seizures was significantly lower in the treated group compared with the control group at 3 months (10% versus 32%; P=." | ( Dua, T; Kalra, V; Kumar, V, 2003) |
| "The risk for oxygen-induced convulsions during routine hyperbaric treatment of most routine conditions is extremely low." | ( Atik, D; Hampson, N, 2003) |
| "Two groups of children with salaam seizures were studied-16 treated with routine anticonvulsants (control group) and 20 who had hydrocortisone added to their routine medication (Cortef-plus group)." | ( CROWTHER, DL, 1964) |
| "Since convulsions associated with the concurrent administration of enoxacin and fenbufen were reported in 1986, the concurrent administration of quinolones and anti-inflammatory drugs has been regulated to be contraindicated or carefully administered." | ( Hori, S; Igarashi, T; Iida, N; Kaneda, M; Kizu, J; Tajima, H; Tsuda, J, 2003) |
| "With pentylenetetrazol (PTZ) induced seizures pre-treated by CBZ, or SR-3, both CBZ and SR-3 were equally effective in providing seizure control and both were superior to the saline control." | ( Mostofsky, DI; Rabinovitz, S; Yehuda, S, 2004) |
| "Measures to treat seizures, hypoglycaemia, electrolyte anomalies and hyperthermia are the therapeutic goals." | ( Refstad, S, 2003) |
| "We have shown that electroconvulsive seizure (ECS), used for the treatment of severe depression, induces proliferation of both neuronal and nonneuronal cells in the adult rat hippocampus." | ( Ekdahl, CT; Hellsten, J; Tingström, A; Wennström, M, 2003) |
| "After several reports of new-onset seizures in children treated with oral baclofen at our institution, we reviewed our experience regarding possible effects of baclofen on seizure induction in a childhood movement disorders program over a 2-year period." | ( Hansel, CR; Hansel, DE; Hoon, AH; Johnston, MV; Levey, EB; Madden, L; Reinhardt, EM; Shindle, MK, 2003) |
| "In this population of adults with seizure disorders, CBZ-ERC twice daily was well tolerated during 12 to 36 months of open-label treatment,with no increase in seizure frequency or decrease in quality of life." | ( Garnett, WR; Hogan, RE; Thadani, VM, 2003) |
| "An 8 year old boy with partial seizures developed maculopapular rashes with itching on day 15 of carbamazepine therapy." | ( Kalita, J; Misra, UK; Rathore, C, 2003) |
| "In patients with seizures due to viable parenchymal cysts, antiparasitic therapy decreases the burden of parasites and is safe and effective, at least in reducing the number of seizures with generalization." | ( Del Brutto, OH; Evans, CA; Garcia, HH; Gilman, RH; Gonzalez, AE; Herrera, G; Martinez, SM; Moulton, LH; Pretell, EJ, 2004) |
| "After 3 years seizure-free period, he had repeated HMS, seven to eight attacks per day, after initiation L-thyroxine treatment." | ( Aydin, A; Baklan, B; Cemeroglu, AP, 2004) |
| "To report a case of seizure activity following gatifloxacin administration during treatment of urosepsis in an intensive care unit." | ( Lederman, JR; Quigley, CA, 2004) |
| "The alterations in clonic seizure threshold, induced by pentylenetetrazole, following the induction of intestinal inflammation by the administration of two consecutive daily oral doses of croton oil, was evaluated in mice." | ( Bahadori, M; Dehpour, AR; Demehri, S; Homayoun, H; Honar, H; Riazi, K, 2004) |
| "Rats treated with ketamine following seizure onset were virtually indistinguishable from nonepileptic controls on a variety of behavioral tasks that included tests on learning, memory, and anxiety." | ( Fournier, NM; Persinger, MA, 2004) |
| "Electroconvulsive seizures, an animal model for electroconvulsive treatment, induce a strong increase in neurogenesis in the dentate gyrus of adult rats." | ( Bengzon, J; Hellsten, J; Mohapel, P; Tingström, A; Wennström, M, 2004) |
| "In naloxone-treated group, the rats' seizure duration and seizure grade [(5." | ( Chang, XZ; Qin, J; Shan, Y; Yang, ZX, 2004) |
| "The antiseizure activity of progesterone in PRKO mice was reversed by pretreatment with finasteride, a 5alpha-reductase inhibitor that blocks the metabolism of progesterone to allopregnanolone." | ( Castaneda, DC; O'Malley, BW; Reddy, DS; Rogawski, MA, 2004) |
| "The prediction of seizure thresholds in electroconvulsive therapy (ECT) remains problematic." | ( Kiyama, S; Nakaoji, T; Ochiai, R; Takeda, J; Yamada, T, 2004) |
| "Repeated seizures were induced in male Wistar rats by daily administration of 3-mercaptopropionic acid (MP) 45 mg/kg i." | ( Brusco, A; García-Rivello, H; Girardi, E; Lazarowski, A; Ramos, AJ, 2004) |
| "Epileptic seizures have been reported in patients on imipenem/cilastatin (Imi/Cil) therapy." | ( Lovic, OS; Susic, V; Zivanovic, D, 2004) |
| "At our institution, new-onset seizures in children on chemotherapy are treated with gabapentin, a nonhepatic enzyme inducer." | ( Hunt, DL; Khan, RB; Thompson, SJ, 2004) |
| "To report a case of loss of seizure control due to hypocalcemia resulting from long-term treatment with phenytoin and phenobarbital." | ( Al-Busairi, WA; Al-Bustan, MA; Al-Mulla, FA; Ali, FE, 2004) |
| "Hypocalcemic seizures are uncommon and underdiagnosed complications of long-term therapy with AEDs." | ( Al-Busairi, WA; Al-Bustan, MA; Al-Mulla, FA; Ali, FE, 2004) |
| "The sustained seizures were subsequently treated with diazepam (10 mg/kg) and pentobarbital (30 mg/kg) and finally terminated 25 min after onset." | ( Aas, P; Andersen, JM; Myhrer, T; Nguyen, NH, 2004) |
| "Differentiation of pseudoseizures from epileptic seizures and hysterical stridor from asthma is key to the treatment of patients." | ( Kaufman, KR; Mohebati, A; Sotolongo, A, 2004) |
| "Nonconvulsive seizures (NCSs) after traumatic and ischemic brain injury are often refractory to antiepileptic drug therapy and are associated with a decline in patient outcome." | ( Hartings, JA; Lu, XM; Moreton, JE; Tortella, FC; Williams, AJ, 2004) |
| "We used "two-hit" rodent seizure model to study the long-term effect of perinatal hypoxia on later kainate (KA) seizure-induced neuronal damage and investigated the therapeutic efficacy of a postseizure treatment protocol in reversing the conditioning effect of early-life seizures." | ( Jensen, FE; Koh, S; Simpson, JN; Tibayan, FD, 2004) |
| "There were three seizures in the first week after initiating glargine therapy." | ( Buckingham, B; Tan, CY; Wilson, DM, 2004) |
| "Age, number of seizures, duration of AED therapy, occurrence of breakthrough seizures, administration of albendazole, and presence of a calcific residue of the SCCG on the CT scan were studied as prognostic factors to predict recurrence of seizures." | ( Jeyaseelan, L; Rajshekhar, V, 2004) |
| "When fed to seizure-prone Mongolian gerbils (Meriones unguiculatus) in a model of epilepsy, hispidulin (10 mg kg(-1) body weight (BW) per day) and diazepam (2 mg kg(-1) BW per day) markedly reduced the number of animals suffering from seizures after 7 days of treatment (30 and 25% of animals in the respective treatment groups, vs 80% in the vehicle group)." | ( Baur, R; Kavvadias, D; Qaiser, MZ; Rausch, WD; Rice-Evans, C; Riederer, P; Sand, P; Schreier, P; Sigel, E; Youdim, KA, 2004) |
| "The authors report a case of convulsion during intra-arterial selective infusion of fasudil hydrochloride (FSD) for treatment of vasospasm following subarachnoid hemorrhage (SAH)." | ( Date, I; Nakashimia, H; Ohmoto, T; Ono, S; Sasahara, W; Sugiu, K; Tokunaga, K, 2004) |
| "The clinical seizures resolved after administration of phenobarbital with normalization of the EEG several days later." | ( Goodkin, HP; Tramonte, JJ, 2004) |
| "Human seizure disorders are a major health concern due to the large number of affected individuals, the potentially devastating consequences of untreated seizure occurrences, and the lack of an effective treatment for all patients." | ( Lin, F; Tan, JS; Tanouye, MA, 2004) |
| "The threshold for the clonic seizures (CST) induced by acute intravenous administration of gamma-aminobutyric acid (GABA)-antagonist pentylenetetrazole (PTZ) was assessed in male and female mice." | ( Dehghani, M; Dehpour, AR; Gaskari, SA; Homayoun, H; Honar, H; Rashidi, N; Riazi, K; Sadeghipour, H, 2004) |
| "Three children being treated for seizures with vigabatrin showed definite clinical findings of peripheral retinal nerve fiber layer atrophy, with relative sparing of the central or macular portion of the retina and relative nasal optic nerve atrophic changes." | ( Buncic, JR; Logan, WJ; MacKeen, LD; Munn, JR; Panton, CM; Westall, CA, 2004) |
| "To report a case of seizure activity associated with oral codeine phosphate administered for analgesia in an elderly woman with end-stage renal disease." | ( Kao, SM; Kuo, SC; Lin, YC; Yang, YH, 2004) |
| "The numbers of spontaneous seizures per day during a 15 min observation interval were recorded for each rat during the treatment period and during an additional 30 days when only tap water was given." | ( Peredery, O; Persinger, MA, 2004) |
| "One of them, soman, can induce severe epileptic seizures and brain damage for which therapy is incomplete." | ( Carpentier, P; Dorandeu, F; Foquin, A; Lallement, G, 2004) |
| "Compared to vehicle, seizures were dramatically reduced in cultures treated with NR2B selective antagonists and slightly increased in cultures treated with moderate-affinity uncompetitive or high-affinity competitive antagonists." | ( Bausch, SB; Wang, XM, 2004) |
| "Soman induced profound limbic convulsions and 30% mortality, leading to increased blood-brain barrier permeability, neural injuries, learning and memory impairments, and physical incapacitation of survived rats pretreated with HI-6." | ( Che, JH; Choi, EK; Ha, YC; Hur, GH; Hwang, SY; Jang, JY; Kim, DJ; Kim, J; Kim, JC; Kim, YB; Park, D; Seong, YH; Shin, S; Yon, JM, 2004) |
| "Seven days post-seizure, the ECS group showed significantly more locomotion following intraperitoneal administration of apomorphine (0." | ( Burnham, WM; Sahebgharani, M; Zarrindast, MR, 2004) |
| "He developed generalized tonic clonic seizures just before the biopsy and was treated with IV midazolam 1 mg and thiopental 60 mg." | ( Agarwal, A; Dhiraaj, S; Pandey, R; Raza, M; Saxena, R; Singh, PK, 2005) |
| "If epilepsy developed, the seizures were less frequent in DZP-treated animals compared to the vehicle group (median 16." | ( Kharatishvili, I; Lukasiuk, K; Narkilahti, S; Nissinen, J; Pitkänen, A, 2005) |
| "The emergency treatment of seizures is an important practical issue, in particular the therapy of status epilepticus." | ( Peters, CN; Pohlmann-Eden, B, 2005) |
| "The therapeutic goal was persistent seizure control, defined as successful interruption of clinical seizure activity within less than 15 min, followed by seizure freedom during intravenous therapy for at least 12h." | ( Peters, CN; Pohlmann-Eden, B, 2005) |
| "One year later he again suffered from convulsions and was treated with carbamazepine in another hospital." | ( Matsushita, H; Sugama, Y; Uji, M, 2005) |
| "The duration and frequency of seizure activities and electrographic seizure onset of 41 patients totally withdrawing from CBZ monotherapy (n = 20), LTG monotherapy (n = 10) and CBZ + LTG combined therapy (n = 11) were intensively studied by therapeutic intensive seizure analysis (TISA) method." | ( Koebnick, C; Pauli, E; Stefan, H; Tilz, C; Wang, B; Wang-Tilz, Y, 2005) |
| "Generalized tonic-clonic seizures are a rare complication of levofloxacin therapy." | ( Christie, MJ; Sikaneta, TG; Tam, PY; Ting, RH; Wong, K, 2005) |
| "After treatment, 8 patients were seizure-free, and 11 others had > or =50% improvement in seizure control, including 11 of the 28 patients for whom treatment with six or more antiepileptic drugs was insufficient." | ( Brotherton, T; Santos, CC, 2005) |
| "The reduction in seizure frequency using ELB138 in dogs with newly diagnosed idiopathic epilepsy was comparable to the reduction in dogs treated either with phenobarbital or primidone." | ( Rieck, S; Rundfeldt, C; Tipold, A, 2006) |
| "The antiseizure effect of tested combinations was not sex-dependent and not reversed by hydrocortisone pretreatment." | ( Borowicz, KK; Czuczwar, SJ, 2005) |
| "The thresholds for the clonic seizures induced by the intravenous administration of gamma-aminobutyric acid (GABA)-antagonist, pentylenetetrazole (PTZ) were assessed in mice." | ( Dehpour, AR; Ebrahimkhani, MR; Ghaffari, K; Homayoun, H; Honar, H; Jannati, A; Kiani, S; Noorian, AR; Rashidi, N; Riazi, K, 2005) |
| "Dyskinesias and seizures are both medically refractory disorders for which cannabinoid-based treatments have shown early promise as primary or adjunctive therapy." | ( Adrian, R; Baratta, J; Giuffrida, A; Piomelli, D; Solbrig, MV, 2005) |
| "Electroconvulsive seizure (ECS)-treatment, a model for electroconvulsive therapy (ECT) has been shown to induce proliferation of endothelial cells in the dentate gyrus (DG) of adult rats." | ( Arvidsson, A; Ekstrand, J; Hellsten, J; Jansson, L; Tingström, A; Wennström, M; West, MJ, 2005) |
| "The latency and incidence of seizures were recorded by an observer who was uninformed of the estrous cycle and dietary treatment conditions of the rats." | ( Frye, CA; Harney, JP; Rhodes, ME; Talluri, J, 2005) |
| "The relative incidence of seizures during the first 28 days of treatment was 3." | ( Britton, J; Farrington, P; Godfrey, C; Hubbard, R; Lewis, S; Smeeth, L; Smith, C; West, J, 2005) |
| "Furthermore, the inhibition of seizure expression in SERs was still apparent 5 weeks after termination of LEV treatment." | ( Ishihara, K; Ji-qun, C; Nagayama, T; Sasa, M; Serikawa, T; Yan, HD, 2005) |
| "QA administration induced seizures in rats and was able to stimulate synaptosomal L-[3H]glutamate release." | ( Abud, J; Schmidt, AP; Souza, DO; Tasca, CI; Tavares, RG, 2005) |
| "Propofol may decrease seizure duration in electroconvulsive therapy." | ( Akcaboy, EY; Akcaboy, ZN; Bayam, G; Dikmen, B; Dilbaz, N; Gogus, N; Yigitbasł, B, 2005) |
| "access at the time of convulsions were randomised into 2 groups and treated with either intramuscular midazolam or intravenous diazepam for control of seizures." | ( Deshmukh, CT; Shah, I, 2005) |
| "There were no seizures in the treated group." | ( Coulter-Smith, SD; Geary, M; O'Donovan, M; Singh, J, 2005) |
| "All animals developed seizures subsequent to this treatment." | ( Li, JX; Liu, KL; Liu, YQ; Ruan, JX; Wang, YA; Yue, YJ; Zheng, JQ; Zhou, WX, 2005) |
| "There was no evidence of any seizure-like convulsions when ARD-353 was administered to mice either i." | ( Chang, KJ; Gengo, PJ; Gross, GJ; Holt, JD; O'Neill, SJ; Pendergast, W; Watson, MJ; Wei, K, 2006) |
| "10/15 patients remained seizure-free on the ketogenic diet in monotherapy." | ( Binder, S; Gertsen, E; Hertzberg, C; Klepper, J; Leferink, M; Leiendecker, B; Näke, A; Scheffer, H; Voit, T; Willemsen, MA, 2005) |
| "Following KA-induced seizures, severe neuronal cell damage was observed in the CA1 and CA3 subfields of hippocampal 3 days after KA administration." | ( Matsumoto, K; Murakami, Y; Sumanont, Y; Tohda, M; Vajragupta, O; Watanabe, H, 2006) |
| "Fifteen of the sixteen patients had no seizures after the administration of carbamazepine." | ( Furukawa, S; Hayashi, T; Ichiyama, T; Matsufuji, H; Nishikawa, M; Suenaga, N, 2005) |
| "Total seizure duration of 720+/-50 s after single PTZ administration (80 mg/kg i." | ( Bahçekapili, N; Sarper Diler, A; Uzüm, G; Ziya Ziylan, Y, 2006) |
| "Therapeutic measures included seizure prophylaxis with phenytoin and total brain radiation therapy of brain metastases from bronchial carcinoma." | ( Loewe, R; Pickl, WF; Stingl, G; Wagner, SN; Wöhrl, S, 2005) |
| "A patient with a history of seizures controlled with long-term carbamazepine therapy developed seizures when he started treatment with oxycodone CR at recommended doses." | ( Brill, S; Gurevich, B; Klein, M; Lifshitz, M; Lottan, M; Rudich, Z; Weksler, N, 2005) |
| "Centrally mediated seizures are a common consequence of exposure to organophosphates (OP) despite conventional treatment with atropine and an oxime." | ( Chapman, S; Gilat, E; Kadar, T, 2006) |
| "Electroconvulsive seizure (ECS)-treatment, an animal model for the antidepressant treatment electroconvulsive therapy, can enhance proliferation of glial cells." | ( Ekstrand, J; Hellsten, J; Lindgren, H; Tingström, A; Wennström, M, 2006) |
| "Pentylenetetrazole-induced seizures in rats treated with L-NAME caused a significant increase in Evans blue dye extravasation into cerebral cortex, diencephalon and cerebellum, as compared with seizures evoked by pentylenetetrazole injection to L-NAME-untreated rats (P<0." | ( Ahishali, B; Arican, N; Elmas, I; Kalayci, R; Kaya, M; Kucuk, M, 2006) |
| "Pentylenetetrazole-induced seizure threshold was increased with the administration of 2 and 10 mg/kg zolpidem as well as with lorazepam." | ( Fahey, JM; Grassi, JM; Greenblatt, DJ; Reddi, JM, 2006) |
| "Without avizafone in the combination, seizures induced by 3 or 4 x LD(50) of soman could not be terminated unless an adjunct therapy consisting of procyclidine (6 mg/kg), diazepam (10 mg/kg), and pentobarbital (30 kg/kg) was given, and the mortality rate was comparatively high (78%)." | ( Aas, P; Enger, S; Myhrer, T, 2006) |
| "Moreover, the duration and severity of seizures developed by htTG transgenics in response to kainic acid administration were significantly more pronounced than those observed in WT mice." | ( Johnson, GV; Roth, KA; Tucholski, J, 2006) |
| "As far as seizure recurrence was concerned, a lower number (16% versus 33%) of intravenous methyl prednisolone treated patient had recurrence, the difference was insignificant." | ( Agarwal, A; Garg, RK; Kar, AM; Prakash, S; Shukla, R; Singh, MK; Verma, R, 2006) |
| "There was no relationship between seizures after etomidate administration and prior seizure history (p = 0." | ( Gaines, BA; Herr, SM; King, C; Pitetti, RD; Roth, KR; Zuckerbraun, NS, 2006) |
| "Pentylenetetrazol (PTZ)-induced seizure in rats, a relevant model of human absence and of generalized tonic-clonic epilepsy, was used to stimulate seizure activity within 30 s of administration while collecting continuous, high-resolution, multislice images at subsecond intervals." | ( Brevard, ME; Ferris, CF; King, JA; Kulkarni, P, 2006) |
| "Treatment with ESM blocked seizures, decreasing PTZ-induced activation in most forebrain areas." | ( Brevard, ME; Ferris, CF; King, JA; Kulkarni, P, 2006) |
| "Treatment to terminate the seizures necessitated intubation and ventilation, and cooling measures brought the temperature within normal limits." | ( Duffy, MR; Swart, M, 2006) |
| "Recurrent spontaneous motor seizures after repeated low-dose systemic treatment with kainate: assessment of a rat model of temporal lobe epilepsy." | ( Castillo, CG; Freed, WJ; Giordano, M; Mendoza, S, 2006) |
| "In addition, convulsive seizure activity was induced by systemic administration of either 4-aminopyridine (4-AP; 10 mg/kg, i." | ( Henry, M; Hescheler, J; Kamp, M; Krieger, A; Radhakrishnan, K; Schneider, T; Weiergräber, M, 2006) |
| "Intranasal lorazepam stopped convulsions within 10 min in 60 (75%) episodes treated (absolute risk 0." | ( Ahmad, S; Ellis, JC; Kamwendo, H; Molyneux, E, 2006) |
| "Acute seizures following brain injury have been associated with a worsening of patient outcome, but they are often undiagnosed and untreated when they occur without motor convulsions." | ( Bautista, CC; Chen, RW; Dave, JR; Hartings, JA; Lu, XC; Tortella, FC; Williams, AJ, 2006) |
| "Magnetic seizure therapy (MST) was developed as an alternative therapy that could reduce postseizure side effects through the induction of more "focal" seizure activity." | ( Amos, Q; Downing, M; Husain, MM; Lisanby, SH; McClintock, S; Stool, L; Thornton, L; White, PF; Zhang, Y, 2006) |
| "Norfloxacin provoked clonic convulsions in rats treated concomitantly with biphenylacetic acid, a major metabolite of the nonsteroidal anti-inflammatory drug fenbufen." | ( Chen, BY; Cheng, NN; Li, XT; Tang, WL; Wang, YM; Zhang, LR, 2006) |
| "Although electroconvulsive seizures (ECS) are widely used as a treatment for severe depression, the working mechanism of ECS remains unclear." | ( Christensen, DZ; Kristiansen, H; Mikkelsen, JD; Olesen, MV; Woldbye, DP, 2006) |
| "Following a literature review, a seizure management training package was developed to enhance the implementation of a trial treatment protocol for the administration of intranasal midazolam (INM)." | ( Coulthard, K; Harbord, M; Kay, D; Kyrkou, M; Kyrkou, N, 2006) |
| "Furthermore, we investigated whether convulsions elicited by intrastriatal MMA administration are accompanied by striatal protein carbonyl content increase and changes in Na(+),K(+)-ATPase activity in rat striatum." | ( Coelho, RC; de Carvalho Myskiw, J; Ferreira, AP; Fighera, MR; Fiorenza, NG; Furian, AF; Mello, CF; Oliveira, MS; Petry, JC; Royes, LF, 2007) |
| "Limbic seizures were evoked in freely moving rats by intrahippocampal administration of pilocarpine via a microdialysis probe." | ( Clinckers, R; Ebinger, G; Meurs, A; Michotte, Y; Smolders, I, 2006) |
| "The rapid onset of seizure development following injection was most likely due to inadvertent intravascular administration." | ( Dorf, E; Holstege, CP; Kelsey, J; Kuntz, AF, 2006) |
| "SCH 23390 protected against seizures, increased the latency to first seizure and reduced the mortality of the animals treated with pilocarpine Theses results suggest that dopamine receptor system receptor subtypes exert opposite functions on the regulation of convulsive activity." | ( Fonteles, MM; Freitas, RM; Sousa, FC; Vasconcelos, SM; Viana, GS, 2006) |
| "Early treatment of prolonged seizures with rectal diazepam has been the method of choice in order to avoid this complication." | ( Batista, D; Bausà, T; Elias, C; Font, D; Hijano, A; Melendez, R; Rocha, A, 2006) |
| "We treated 52 prolonged seizures in 10 patients enrolled in the study." | ( Batista, D; Bausà, T; Elias, C; Font, D; Hijano, A; Melendez, R; Rocha, A, 2006) |
| "Following 6 stage-5 once daily convulsive seizures, guanfacine or idazoxan were re-administered." | ( McIntyre, DC; Shin, RS, 2007) |
| "We studied daily rhythms of chronic seizure activity and behavior in adult rats and mice treated with the cholesterol biosynthesis inhibitor AY-9944 (AY) during early postnatal development." | ( Bercovici, E; Cortez, MA; Mistry, N; Persad, V; Serbanescu, I; Shukla, R; Snead, OC; Stewart, LS, 2006) |
| "There was no difference in onset of seizure time between the pyridoxine-treated group of rats and the control rats." | ( Cameron, D; Chase, PB; Fernandez, MC; Roe, DJ; Walter, FG; Wolfson, M, 2006) |
| "The relationship between seizure duration and bispectral index (BIS) has not been studied well in modified electroconvulsive therapy (mECT)." | ( Minami, T; Miyazaki, S; Morimoto, K; Muratani, T; Shimizu, S; Tanaka, M, 2006) |
| "In addition, convulsions induced by lithium-methomyl treatment were associated with widespread neurodegeneration of limbic structures." | ( Blaszczak, P; Calderazzo, L; Cavalheiro, EA; Dekundy, A; Kaminski, RM; Parada-Turska, J; Turski, WA, 2007) |
| "In general, seizure length does not correlate with clinical outcome with electroconvulsive therapy (ECT), but whether markedly short seizures are still therapeutic is unknown." | ( Brady, BM; Hooten, WM; Laurila, DR; Lewis, CL; Marienau, ME; Niemeyer, KD; Rasmussen, KG; Schroeder, DR; Spackman, TM; Sun, NM, 2006) |
| "In this post hoc analysis, individual seizure counts from four double-blind trials of adjunctive treatment with levetiracetam were analyzed by non-linear mixed-effects modeling (NONMEM)." | ( Snoeck, E; Stockis, A, 2007) |
| "LEV was considered effective if seizure cessation or >75% seizure reduction occurred in the 24 h after starting LEV (compared with the previous 48 h), requiring no further antiepileptic drug (AED) treatment." | ( Amaro, S; Carreño, M; Delgado, R; Donaire, A; Falip, M; Maestro, I; Toledo, M, 2006) |
| "The onset of tonic seizures induced by strychnine was increased between 40-140% in the case of the coground system depending on dose and time of carbamazepine administration." | ( Adibkia, K; Anoush, M; Barzegar-Jalali, A; Barzegar-Jalali, M; Hanaee, J; Nayebi, AM; Sistanizad, M; Valizadeh, H, 2006) |
| "Review of the spontaneous reports on convulsions showed that patients with nephropathy, patients over 75 years and patients with a history of convulsive diseases were more likely to develop convulsions during LVX therapy." | ( Kawai, H; Komiya, M; Matsumoto, T; Nakayasu, T; Shimada, J; Yamaguchi, H; Yokoyama, H, 2007) |
| "We monitored the onset of seizures in patients undergoing osmotic disruption of BBB (BBBD) followed by intraarterial chemotherapy (IAC) to treat primary brain lymphomas." | ( Angelov, L; Diglaw, T; Fazio, V; Franic, L; Granata, T; Hallene, K; Hernandez, N; Janigro, D; Marchi, N; Masaryk, T; Najm, I, 2007) |
| "Treatment with PHT led to complete seizure control in two animals and a >50% reduction of seizure frequency in three other rats, which were considered PHT responders." | ( Bethmann, K; Brandt, C; Löscher, W, 2007) |
| "We investigated whether electroconvulsive seizure (ECS) in rats stimulates cellular proliferation in the PFC immediately and four weeks after the treatments." | ( Carlezon, WA; Cohen, BM; Dow, AL; Edwin, F; Eisch, AJ; Heckers, S; Ongür, D; Patel, TB; Pohlman, J, 2007) |
| "Theophylline-associated seizures (TAS) are considered a neurologic emergency, as they can sometimes be intractable and difficult to stop with standard treatments such as intravenous administration of diazepam." | ( Yoshikawa, H, 2007) |
| "The time-series records of seizures and processes of drug administrations were investigated." | ( Enoki, H; Matsubayashi, R; Matsubayashi, T; Nagasaki, R; Nakashima, Y; Ohro, Y; Takeda, S; Yokota, T, 2007) |
| "In two patients, seizures were resistant to single-dose CH therapy, and their doses of CH were 33." | ( Enoki, H; Matsubayashi, R; Matsubayashi, T; Nagasaki, R; Nakashima, Y; Ohro, Y; Takeda, S; Yokota, T, 2007) |
| "We report a case of neonatal seizures after lidocaine administration for circumcision." | ( Finkelstein, Y; Koren, G; Railton, C; Rezvani, M; Verjee, Z, 2007) |
| "Treatment of tumor-induced seizures is often inadequate with traditional antiepileptic drugs (AED) due to a variety of factors, including activation of glutamatergic NMDA receptors, alterations of neuronal input pathways, and tumor growth." | ( Dalton, J; Goldlust, S; Newton, HB; Pearl, D, 2007) |
| "Transient seizures were observed in the K/DET treated animals during induction." | ( Jago, M; Stegmann, GF, 2006) |
| "In 1929, yi jing (pestilent convulsion) was prevalent in Shanghai, Yan Cangshan, a noted modern physician, was active in treating and rescuing the patients." | ( Wu, WQ, 2006) |
| "Thus, the Li-pilocarpine seizure model may, despite its lack of face validity, be a biochemical marker for a model of mania treatment in animals." | ( Belmaker, RH; Bersudsky, Y, 2007) |
| "Each patient was without seizure on levetiracetam monotherapy, and there were no adverse effects." | ( Rotenberg, JS; Shoemaker, MT, 2007) |
| "Mortality rate and seizure score of p38alpha(+/-) mice administered with kainate were significantly reduced compared with the case of wild-type (WT) mice." | ( Furuya, M; Hama, H; Kasuya, Y; Kimura, S; Kuwaki, T; Matsuo, Y; Mizuhashi, S; Nakamura, A; Namiki, K; Sudo, T; Tokuhara, N; Yano, S, 2007) |
| "The relative risk of seizure remission in treatment versus control was 1." | ( Mazumdar, M; Pandharipande, P; Poduri, A, 2007) |
| "Sevoflurane-induced seizures are most often described during mask induction of anesthesia when high concentrations of the volatile agent are administered concomitant with alveolar hyperventilation." | ( Iqbal, Z; Kumar, V; Markan, S; Mohanram, A; Pagel, PS, 2007) |
| "Minor motor seizures from the 10th month onwards are successfully treated with Valproate." | ( Creemers, JW; Mullaart, RA; Reimer, A; Wortmann, SB, 2008) |
| "Theophylline-associated seizures (TAS) are considered a neurologic emergency, as they can sometimes be intractable and difficult to stop with standard treatments such as intravenous administration of diazepam." | ( Yoshikawa, H, 2007) |
| "The significant proportion of seizure-free cases (27%) on duotherapy is suggesting the usefulness of combination therapy in achieving seizure-freedom in epilepsies refractory to single drug treatment." | ( Auvinen, A; Keränen, T; Kharazmi, E; Peltola, J; Peltola, M; Raitanen, J, 2008) |
| "In patients presenting with seizures due to single viable parenchymal neurocysticercosis, albendazole hastens the resolution of SSECTL if treatment is given in the early phase of the illness." | ( Chattopadhyay, A; Khandelwal, N; Sawhney, IM; Thussu, A, 2008) |
| "The hypocalcaemia and seizure activity had resolved with medical therapy, with normal calcium levels and no seizures for a month." | ( Rewari, V; Sethi, D, 2007) |
| "Neonatal seizures appeared at 21 hours and empiric anticonvulsive and antimicrobial treatment was started." | ( Gardiner, J; Kaczala, GW; Messer, MA; Poskitt, KJ; Prendiville, JS; Senger, C, 2008) |
| "Acute "silent" seizures after brain injury are associated with a worsening of patient outcome and are often refractory to anti-epileptic drug (AED) therapy." | ( Gryder, D; Hartings, JA; Tortella, FC; Williams, AJ, 2008) |
| "They show, in two rodent seizure models, that leptin administered directly to the brain or nasal epithelium suppresses seizures via direct effects on glutamate neurotransmission in the hippocampus." | ( Diano, S; Horvath, TL, 2008) |
| "A subsample of 67 adult patients with partial seizures participating in a randomized, double-blind study comparing the cognitive effects of adjunctive lamotrigine (LTG) and adjunctive topiramate (TPM) was administered Performance On-Line (POL) in addition to a battery of neuropsychological tests at baseline, week 8 and week 16 of treatment." | ( Blum, DE; Caldwell, PT; Drazkowski, JF; Hammer, AE; Kustra, RP; Mills, KC, 2008) |
| "The role of PGE(2) in the convulsions induced by PTZ was further investigated by administering anti-PGE(2) antibodies (4 microg/2 microl, i." | ( Bohrer, D; Castelli, M; Cavalheiro, EA; Ferreira, J; Fighera, MR; Fiorenza, NG; Furian, AF; Machado, P; Mello, CF; Oliveira, MS; Royes, LF; Veiga, M, 2008) |
| "In infants with idiopathic low seizure threshold and fever, theophylline administration might possibly trigger a seizure." | ( Izumi, T; Korematsu, S; Miyahara, H; Nagakura, T; Suenobu, S, 2008) |
| "REM sleep rebound and reduced seizure threshold) upon treatment discontinuation is reported for GABA(A) receptor allosteric modulators acting via the benzodiazepine binding site, e." | ( Anderson, NJ; Cremers, TI; Ebert, B; Fahey, JM; Rasmussen, S; Sánchez, C; Vogel, V, 2008) |
| "Since seizure duration can influence the therapeutic effect of ect it is advisable to use bilateral electrode placement in patients with cardiovascular risk factors and to administer esmolol prior to seizure induction." | ( Birkenhäger, TK; Bruijn, JA; Groenland, TH; Kusuma, A; Mulder, PG; Pluijms, EM; van den Broek, WW, 2008) |
| "While propofol is known to shorten seizures during electroconvulsive therapy, in our previous study on patients with schizophrenia, there was no need for more frequent restimulations when using propofol compared with etomidate." | ( Gábor, G; Judit, T; Zsolt, I, 2007) |
| "After etomidate induction, seizure durations registered either by EEG or by EMG were longer than propofol treated cases (EEG: 49." | ( Gábor, G; Judit, T; Zsolt, I, 2007) |
| "This is a report of a jacksonian seizure in a non-psychotic manic patient who was treated with right prefrontal high frequency rTMS concomitant to pharmacotherapy." | ( Papadimitriou, GN; Psarros, C; Sakkas, P; Soldatos, CR; Theleritis, CG, 2008) |
| "Duration of seizure also significantly increased in propofol (5 mg/kg) treated group, but at 2 mg/kg of propofol treatment, no significant difference was observed." | ( Medhi, B; Prakash, A; Puri, A; Saikia, B, 2008) |
| "Both the patients developed seizures of various types that have been successfully treated with zonisamide." | ( Amamiya, S; Araki, A; Fujieda, K; Kajihama, A; Ohinata, J; Sugai, R; Suzuki, N; Takahashi, S; Tanaka, H, 2008) |
| "We determined if seizure induction and seizure-induced cell death are affected differentially in young adult, mature, and aged male C57BL/6J and FVB/NJ mice administered the excitotoxin, kainic acid." | ( Bloom, CS; Chancer, ZO; Lorenzana, A; McCord, MC; Schauwecker, PE, 2008) |
| "Occurrence of seizures following long-term oral administration of caffeine (0." | ( Costentin, J; El Yacoubi, M; Ledent, C; Parmentier, M; Vaugeois, JM, 2008) |
| "Decontamination and appropriate seizure or muscle fasciculation control were the basis of treatment." | ( Dymond, NL; Swift, IM, 2008) |
| "Notwithstanding the reduction in seizure severity, cell death (60-90% of cell loss in KA-treated animals) in limbic regions was unchanged by herbimycin A and K252a." | ( Mello, LE; Queiroz, CM, 2008) |
| "Tardive seizure is a serious adverse reaction of electroconvulsive therapy (ECT)." | ( Isse, K; Nakamura, M; Saito, T; Watari, M, 2008) |
| "Data collected included demographics, seizure type, etiology of seizures, age at onset of seizures and at initiation of LTG treatment, number of antiepileptic drugs (AEDs) prior to LTG, dose of LTG, length of follow-up, treatment response, and adverse events." | ( Hardison, HH; Khurana, DS; Kothare, SV; Legido, A; Marks, HG; Melvin, JJ; Piñol-Ripoll, G; Valencia, I, 2009) |
| "Because of myoclonic jerks and generalized seizures, benzodiazepines were administered." | ( Beyrau, R; Bodmer, M; Burkard, T; Haschke, M; Krähenbühl, S; Kummer, O, 2008) |
| "A single dose of MDZ terminated convulsions in all (100%), 9/12 (75%) and 5/8 (63%) children following IV, IM and buccal administration." | ( Edwards, G; Kokwaro, GO; Muchohi, SN; Newton, CR; Ogutu, BR; Ward, SA, 2008) |
| "To estimate the rate of new-onset seizure in ADHD patients in relation to ADHD pharmacotherapy." | ( Holdridge, KC; Hornbuckle, K; Johannes, CB; McAfee, AT; Walker, AM, 2008) |
| "Incidence of seizure was calculated for observation time during treatment with atomoxetine and stimulants/bupropion." | ( Holdridge, KC; Hornbuckle, K; Johannes, CB; McAfee, AT; Walker, AM, 2008) |
| "Sixteen were seizure-free during treatment and not included in the conditional analysis." | ( Briggs, DE; French, JA; Lee, CM; Spiegel, K, 2008) |
| "Three patients presented seizures during ertapenem therapy." | ( Abusada, NJ; Fica, AE, 2008) |
| "While 47 of the cases were seizure-free on pyridoxine monotherapy, over time, eight other cases also required the concomitant use of anticonvulsants for effective seizure control, while the remainder continued to have recurrent seizures, despite the use of pyridoxine and multiple anticonvulsants." | ( Basura, GJ; Gospe, SM; Hagland, SP; Wiltse, AM, 2009) |
| "Although it is controversial that seizure duration can influence the efficacy of electroconvulsive therapy (ECT), a missed or brief seizure is considered less effective ECT." | ( Inoue, A; Kano, A; Miyaoka, H; Nakajima, K; Okutomi, T; Sawayama, E; Sawayama, T; Takahashi, M, 2008) |
| "It is characterized by infantile seizures refractory to anticonvulsive treatments, microcephaly, delays in mental and motor development, spasticity, ataxia, dysarthria and other paroxysmal neurologic phenomena, often occurring prior to meals." | ( Cano, A; Chabrol, B; Ticus, I, 2008) |
| "VPC inhibits 4-AP-induced seizures and hearing loss, even after post-treatment, at a concentration about 10 times lower than CBZ." | ( Nekrassov, V; Sitges, M, 2008) |
| "We studied 23 patients with cancer and seizures treated with levetiracetam." | ( Fisher, PG; Partap, S, 2009) |
| "Pyridoxine-dependent seizures are a rare condition recognized when numerous seizures respond to pyridoxine treatment and recur on pyridoxine withdrawal." | ( Jakobs, C; Jozwiak, S; Kacinski, M; Kaczorowska, M; Kmiec, T; Kroczka, S; Salomons, GS; Struys, EA, 2008) |
| "Current treatments involve seizure suppression using antiepileptic drugs (AEDs); however, many patients remain refractory to current treatments or suffer serious side effects." | ( Batts, TW; Bertram, EH; Brown, ML; Hargus, NJ; Jones, PJ; Merrick, EC; Patel, MK; Stables, JP; Wang, Y, 2009) |
| "Because of poor seizure even at maximum electrical dosage, aminophylline was administered just before initiating electroconvulsive therapy." | ( Kaneko, S; Katagai, H; Kikuchi, A; Yasui-Furukori, N, 2009) |
| "Consecutive seizures in each animal were (1) treated with active rTMS, (2) treated with sham rTMS, or (3) were untreated." | ( Birnbaum, D; Harrington, M; Jensen, FE; Muller, P; Pascual-Leone, A; Riviello, JJ; Rotenberg, A, 2008) |
| "Patients with brain tumors and seizures should be treated with non-enzyme-inducing antiepileptic drugs (AED)." | ( Novy, J; Rossetti, AO; Stupp, R, 2009) |
| "Cocaine-induced paroxysmal activity and convulsions were evaluated in rats surgically implanted with radiotelemetry devices (N=6 per treatment group)." | ( Baladi, MG; Cooper, ZD; Jutkiewicz, EM; Narasimhan, D; Sunahara, RK; Woods, JH, 2009) |
| "In untreated controls, the percent of seizure induced by CC50 and percent of death among mice having convulsions were 50 and 20, respectively." | ( Küçükhüseyin, C; Yillar, DO, 2008) |
| "Experimental acute seizure in mice was induced by intraperitoneal injection of KA (30 mg/kg), and mice were provided for experiments after 48 h of KA treatment." | ( Honda, N; Nishimura, A; Shibata, N; Sugioka, N; Takada, K, 2008) |
| "Folinic acid-responsive seizures and pyridoxine-dependent epilepsy are two treatable causes of neonatal epileptic encephalopathy." | ( Gallagher, RC; Hyland, K; Jakobs, C; Mercimek-Mahmutoglu, S; Plecko, B; Rosenberg, EH; Salomons, GS; Scharer, G; Stockler-Ipsiroglu, S; Struys, EA; Van Hove, JL; Waters, PJ, 2009) |
| "There was a dramatic reduction in seizure frequency with rapamycin therapy." | ( Butler, IJ; Koenig, MK; Muncy, J, 2009) |
| "Daily repeated epileptic seizures were induced for 12 days by intraperitoneal administration of 4-aminopyridine (4-AP; 4." | ( Bakos, M; Borbély, S; Czégé, D; Dobó, E; Mihály, A; Molnár, E; Szucs, B; Világi, I; Vincze, A, 2009) |
| "Hippocampal EEG seizures were continuously monitored before, during and after treatment." | ( Aronica, E; Gorter, JA; Holtman, L; Queiroz, CM; van Schaik, R; van Vliet, EA, 2009) |
| "Talampanel treatment suppressed seizures in a dose-dependent manner, with maximal effect at 7." | ( Aujla, PK; Fetell, MR; Jensen, FE, 2009) |
| "Differential effects of postseizure treatment on functions of the thyroid, pancreas, and spleen were indicated." | ( Blomme, CG; Dupont, MJ; George, KR; Mazzuchin, A; Persinger, MA; Rico, T; St-Pierre, LS; Stewart, LS, 2009) |
| "Scopolamine treatment caused convulsions only in the animals given solid food in the first 30 min; no convulsions were observed in the animals given slurry food, liquid food ad libitum, gavage, or placebo." | ( Kara, I; Nurten, A; Ozen, I; Ozerman, B, 2009) |
| "After repeated treatment the PTZ seizure threshold was not different between the two drugs, while differences in sedation became larger than after the acute treatment." | ( Pericić, D; Vlainić, J, 2009) |
| "Finally, audiogenic seizures could be induced in wild-type mice by coadministering CGP 46381 and the mGluR5-positive allosteric modulator 3-cyano-N-(1,2 diphenyl-1H-pyrazol-5-yl) benzamide." | ( Hampson, DR; Heximer, SP; Pacey, LK, 2009) |
| "We describe an 11-year-old girl with a seizure disorder who developed fever, rash, rhabdomyolysis, and multiorgan failure 2 weeks after commencing a transition from sodium valproate to lamotrigine therapy." | ( Dargan, PI; Ferguson, LP; Hood, JL; Tibby, SM, 2009) |
| "Neonatal seizures have devastating consequences for brain development and are inadequately treated by available antiepileptics." | ( Barnett, SM; Kahle, KT; Sassower, KC; Staley, KJ, 2009) |
| "Although seizures in brain tumor patients are common, the knowledge on optimal anti-seizure therapy in this patient group is limited." | ( Rijsman, RM; Taphoorn, MJ; van Breemen, MS; Vecht, CJ; Walchenbach, R; Zwinkels, H, 2009) |
| "The duration of NMDA seizures was longer after acute MA administration relative to animals without acute MA pretreatment in both control groups." | ( Bernásková, K; Matejovská, I; Rokyta, R; Schutová, B; Slamberová, R, 2009) |
| "Ciprofloxacin-associated seizures (CAS) occur most commonly in patients with special risk factors that may cause accumulation of drug (high doses of the drug, old age, renal insufficiency, drug interactions) or that may decrease the threshold of epileptogenic activity (electrolyte abnormalities, history of seizures, electroconvulsive therapy)." | ( Agbaht, K; Bayraktar, M; Bitik, B; Piskinpasa, S; Topeli, A, 2009) |
| "This type of seizures never appeared in caffeine-treated 25-day-old animals." | ( Kubová, H; Mares, P; Tchekalarova, J, 2009) |
| "She developed generalized seizures shortly after the administration of flumazenil." | ( Pedersen, LM; Petersen, M; Søndergaard, I, 2009) |
| "We compared the seizure activity as well as seizure lethality in 2- and 6-month-old mice, transgenic for the above-mentioned point mutation, and their wildtype littermates and found that mice harboring the hN141I mutation showed a relative resistance to excitotoxic treatment." | ( Gunther, T; Hüll, M; Schüle, R; Schulte, EC; Slawik, H, 2009) |
| "The presence of multiple seizures prior to medical treatment has been suggested as a potential predictor of poor outcome." | ( Brandt, C; Löscher, W, 2010) |
| "Before treatment with PB, average seizure frequency in PB nonresponders was significantly higher than seizure frequency in responders, which, however, was due to six nonresponders that exhibited > 3 seizures per day." | ( Brandt, C; Löscher, W, 2010) |
| "The second child in family B developed seizures on the seventh day, because pyridoxine maintenance therapy had not been instituted after birth." | ( Been, JV; Bok, LA; Jakobs, C; Rijper, EA; Struys, EA; Willemsen, MA, 2010) |
| "The results suggest that seizure activity is necessary for the expression of depression-like behavioral symptoms and confirm that epileptogenesis can be prevented by early and chronic treatment." | ( Kulikov, MA; Kuznetsova, GD; Sarkisova, KY; van Luijtelaar, G, 2010) |
| "Neonatal seizures in which hypoxic-ischemic encephalopathy is the main triggering etiology have a challenging diagnosis and limited efficacy of treatment." | ( Dacosta, JC; de Oliveira, IM; Dolganov, A; Greggio, S; Henriques, JA; Menegat, FD; Rosa, RM, 2009) |
| "Clonic seizures were rare in NMDA-treated P25 rats, but valproate pretreatment increased their incidence significantly." | ( Kubová, H; Mares, P, 2010) |
| "On day 15, seizure susceptibility was tested by administration of pentylenetetrazole (40 mg/kg i." | ( Avti, PK; Chakrabarti, A; Khanduja, KL; Medhi, B; Prakash, A, 2009) |
| "Theophylline-associated seizures (TAS) often progress to prolonged or treatment-resistant convulsions." | ( Fukuda, M; Hino, H; Ishii, E; Kuzume, K; Morimoto, T; Suzuki, Y, 2010) |
| "Tonic flexion convulsion was occurred three fifth in the wild type mice group by administration of PTZ, but tonic flexion was not observed in NCX1 knockout mice groups." | ( Baba, A; Honda, K; Iwamoto, T; Kaneko, E; Kita, S; Komuro, I; Matsuda, T; Saito, R; Takano, Y; Tanaka, Y, 2009) |
| "Accordingly, the risk of occurrence of convulsion related to TBPM-PI administration was low compared to IPM/CS administration, and TBPM-PI was considered to be less potential to induce convulsions in clinical use." | ( Kurata, Y; Kurosawa, T; Nawa, T; Shibasaki, S; Suzuki, H; Yagi, Y, 2009) |
| "This study of LEV versus PHT for seizure prevention in the NSICU showed improved long-term outcomes of LEV-treated patients vis-à-vis PHT-treated patients." | ( Lindsell, CJ; Sangha, KS; Shutter, LA; Szaflarski, JP, 2010) |
| "Furthermore, a strong reduction of seizure activity and cytokine production was observed in animals treated with anti-c-Jun siRNAs." | ( Cardoso, AL; Costa, P; Culmsee, C; de Almeida, LP; de Lima, MC; Plesnila, N; Simões, S; Wagner, E, 2010) |
| "PTZ-induced seizure severity is decreased in FRAXAD mice pre-treated with the mGluR(5) antagonist MPEP." | ( Malter, JS; Westmark, CJ; Westmark, PR, 2009) |
| "After 5 days of admission, clonic convulsions that progressed to generalized seizures were noted following the intravenous administration of the tranexamic acid." | ( Chen, HC; Chen, SC; Huang, MS; Wang, CS; Yang, CJ, 2011) |
| "Food intake triggers convulsions in fasted mice and rats treated with antimuscarinic drugs, scopolamine or atropine." | ( Baran, E; Enginar, N; Karamürsel, Y; Nurten, A; Zengin, A, 2010) |
| "Results showed that seizures alter reference memory when compared to saline-treated animals." | ( de Freitas, RM; de Sales Santos, IM; Feitosa, CM, 2010) |
| "The average latency to onset of clonic seizure was prolonged by 1 time and the average PTZ threshold increased 1 time in the nifedipine, the levetiracetam and the flumazenil treatment groups." | ( Bian, FZ; Wang, L; Wang, YH; Wang, YX, 2010) |
| "Onset of convulsions and death were observed in rats with increased CYP2E1 activity, whereas convulsions and death did not appear in rats within 1 h after treatment with AN alone." | ( Aschner, M; Fangan, H; Guangwei, X; Rongzhu, L; Shizhong, W; Suhua, W; Wenrong, X; Xiaowu, Z; Ye, Z, 2010) |
| "Median percent reductions in seizure frequency per 28 days from baseline to maintenance (intention-to-treat, ITT) were 37." | ( Biton, V; Chung, S; Doty, P; Hebert, D; Krauss, G; Rudd, GD; Sperling, MR, 2010) |
| "At present, neonatal seizures are usually treated with Phenobarbital (PB) despite the limited efficacy and the potential risk this treatment holds for the developing brain." | ( Bast, T; Bussmann, C; Ebinger, F; Fürwentsches, A; Philippi, H; Pöschl, J; Ramantani, G; Rating, D; Schubert, S, 2010) |
| "Five patients remained seizure free after 3 months with ongoing LEV monotherapy." | ( Bast, T; Bussmann, C; Ebinger, F; Fürwentsches, A; Philippi, H; Pöschl, J; Ramantani, G; Rating, D; Schubert, S, 2010) |
| "asiatica; and PTZ-induced seizure rats pretreated with diazepam (2mg/kg body wt)." | ( Chetan, PS; Lokanatha, V; Prasad, KS; Rajendra, W; Visweswari, G, 2010) |
| "In Experiment 3, in the seizure-tested animals, subcutaneous administration of 400mg/kg of DHA significantly increased latency to PTZ seizure onset 1 hour postinjection relative to the saline- and OA-injected controls, which did not differ significantly from each other (P>0." | ( Bala, S; Burnham, WM; Jeffrey, MA; Taha, AY; Taha, NM, 2010) |
| "After PTZ administration, mice showed myoclonic seizure (MCL) and clonic seizure (CL) in order." | ( Fujiwara, A; Kamei, C; Takechi, K; Watanabe, Y, 2010) |
| "Based on their seizure scores during treatment and in a screening test performed 2 weeks post-treatment, the PTZ-treated animals were retrospectively divided into the kindled group and the unkindled group." | ( Fang, F; Lei, H, 2010) |
| "One to seven seizures were recognized before starting CBZ or Lidocaine therapy, followed by complete cessation in 57 episodes and one or two recurrent seizures in five." | ( Komatsu, M; Kubota, T; Nakajima, M; Okumura, A; Shimakawa, S; Tanabe, T, 2011) |
| "Five patients (83%) experienced generalized seizures during concurrent VPA-carbapenem treatment, including two with no prior history of seizures or epilepsy." | ( Golightly, LK; Jones, MA; Kick, SD; Tobin, JK, 2009) |
| "Rats had seizure epilepticus in 30 min after administrated of pilocarpine." | ( Jiang, W; Li, XW; Wang, Y; Wei, D; Zhang, SJ, 2010) |
| "Seizure behaviors or duration of seizure were not changed significantly by DBS treatment." | ( Hashizume, K; Hori, T; Kato, K; Maehara, M; Okada, Y; Tanaka, T; Urino, T, 2010) |
| "We report 3 cases of clinical seizure activity associated with nitrous oxide administration for pediatric procedural sedation." | ( Doescher, JS; Zier, JL, 2010) |
| "This noninferiority analysis compares seizure outcomes and side effects in patients with glioma treated with phenytoin and levetiracetam monotherapy." | ( Anderson, SK; Lachance, DH; Merrell, RT; Meyer, FB, 2010) |
| "The stimulus dose and the seizure duration of ECT treatments with concurrent LMT (≥200 mg/d) were compared with the stimulus dose and seizure duration of ECT treatments without concurrent LMT." | ( Demunter, H; Peuskens, J; Roelens, Y; Sienaert, P; Van Heeringen, C; Vansteelandt, K, 2011) |
| "Missed seizures, however, occurred more frequently during ECT treatments with concurrent LMT." | ( Demunter, H; Peuskens, J; Roelens, Y; Sienaert, P; Van Heeringen, C; Vansteelandt, K, 2011) |
| "Kainate-induced seizure behavior progressed further in OVX rats, but was attenuated in prolactin-treated rats, both intact and OVX, compared to vehicle-treated rats." | ( Cerbón, M; Morales, T; Tejadilla, D, 2010) |
| "There was neither improvement in seizure nor any significant changes in lipid peroxidation and antioxidant enzyme levels in etoricoxib-treated group." | ( Khanduja, KL; Medhi, B; Pandhi, P; Rao, RS, 2010) |
| "In the pentylenetetrazole-induced seizure model, the administration of 1 mg/kg and 2 mg/kg amlodipine protected 33 percent of the animals from mortality, and 67 percent were protected with the administration of 4 mg/kg." | ( Sathyanarayana Rao, KN; Subbalakshmi, NK, 2010) |
| "The time of seizure control averaged 40+/-32 minutes in the midazolam group compared with 69+/-24 minutes in the diazepam group after maintenance treatment (P<0." | ( Tang, RH; Zhou, JB, 2010) |
| "The median time to seizure was compared between observers told the animal received placebo and those told the animal received active treatment." | ( Cleveland, NR; Heard, KJ; Krier, S, 2010) |
| "The reported median time to seizure was similar for observers told that the animals were treated with placebo and those told they were treated with study medication." | ( Cleveland, NR; Heard, KJ; Krier, S, 2010) |
| "Eight infants with seizures were treated with phenytoin from 2 weeks to 3 months of age." | ( Banwell, B; Cheng, A; Freeman, D; Levin, S; Rieder, M; Seabrook, JA, 2010) |
| "A 5-month-old boy with migrating partial seizures in infancy acquired bromoderma 4 weeks after initiating potassium bromide (KBr) therapy (60mg/kg/day)." | ( Komaki, H; Kosaka, M; Nabatame, S; Nakagawa, E; Saito, Y; Sakuma, H; Sasaki, M; Sugai, K; Uchiyama, K, 2010) |
| "The greatest attenuation of convulsive seizures, to a level consisting only of motor excitation, was obtained in 60% of the rats between 1 and 2 h after administration." | ( Lukomskaya, NY; Magazanik, LG; Oganesyan, GA; Vataev, SI; Zhabko, EP, 2010) |
| "Thirty-three subjects with nonzero nonepileptic seizure rates at baseline were included in intent-to-treat analysis of the primary outcome." | ( Blum, AS; Keitner, GI; LaFrance, WC; Machan, JT; Miller, IW; Papandonatos, GD; Ryan, CE, 2010) |
| "Delay in onset of PTZ-induced seizures with CZMME compared with positive control and placebo-treated groups confirmed the improved brain uptake." | ( Ambikanandan, M; Ankur, K; Florence, K; Kumar, BA; Kumar, MA; Manisha, L, 2011) |
| "Sex, age, familial history, type of seizures and AED treatment were noted and EEG monitoring, MRI and CT scanning, and developmental and psychomotor evolution were investigated." | ( Caraballo, R; Cersósimo, R; Flesler, S; Sakr, D, 2010) |
| "A reduction in seizure frequency by 50% of the baseline was considered as 'response' (significant change), meriting further continuation of pyridoxine therapy." | ( Gulati, S; Kalra, V; Mishra, D; Saha, N; Seth, R, 2010) |
| "To determine the threshold for clonic seizures, PTZ was administered intravenously." | ( Asghari-Roodsari, A; Dehpour, AR; Javadi-Paydar, M; Khodadad, TK; Lesani, A; Norouzi, A; Shirkhodaei, M, 2010) |
| "In the remaining animals that exhibited seizures, KB-R7943 pretreatment delayed the onset of seizures and status epilepticus, and reduced seizure severity." | ( Martinez, Y; N'Gouemo, P, 2010) |
| "At the dose administered, non-seizure and sustained seizure responses were observed in both agent groups and in the tabun-exposed group some subjects experienced an unsustained seizure response." | ( Acon-Chen, C; McDonough, JH; O'Donnell, JC; Shih, TM, 2010) |
| "The trend to increased seizure frequency in the tranexamic acid group may be a direct consequence of this treatment, consistent with other recently published reports." | ( Berman, M; Cardone, D; Dunning, J; Gerrard, C; Jenkins, D; Klein, A; Sharples, L; Tsui, S; Vuylsteke, A, 2010) |
| "Behavioral and electroencephalographic seizures were monitored for 20 min following pentetrazol administration." | ( Fukuhara, S; Kaida, Y; Kamei, C; Takechi, K; Uehara, T; Watanabe, Y, 2011) |
| "In vivo, KA administration induced seizures and the same neurodegenerative events exhibited in vitro." | ( Alapafuja, SO; Bahr, BA; Butler, D; Hwang, J; Karanian, DA; Makriyannis, A; Naidoo, V; Nikas, SP; Vadivel, SK; Wood, JT; Zhao, J, 2011) |
| "The attenuation in the drop of NMDA seizure threshold (percentage of reversal) was 58 and 20 % upon acute intraperitoneal administrations of magnesium chloride hexahydrate (28 mg magnesium/kg) and the antioxidant ebselen (20 mg/kg), respectively." | ( Agnani, G; Bac, P; Delplanque, B; Durlach, J; German-Fattal, M; Maurois, P; Pages, N; Poupaert, J; Vamecq, J, 2009) |
| "Therapy is often unnecessary and seizures spontaneously end at puberty." | ( Fusco, L; Specchio, N; Trivisano, M; Vigevano, F, 2010) |
| "To examine seizure thresholds, increasing doses of pilocarpine were administered to adult mice and seizures were scored behaviorally." | ( Aaron, G; Asik, K; Briggs, SW; Lombroso, P; Naegele, J; Walker, J, 2011) |
| "Neonatal seizures are often refractory to treatment with initial antiseizure medications." | ( Abend, NS; Clancy, RR; Dlugos, DJ; Gutierrez-Colina, AM; Monk, HM, 2011) |
| "All patients had seizure disorders that were treated with anticonvulsants." | ( Moldovan, K; Pouratian, N; Schiff, D; Shaffrey, ME; Sherman, JH; Starke, RM; Yeoh, HK, 2011) |
| "The data of the patients treated for seizures (convulsions, epileptic seizures, disturbance of consciousness and epileptic seizures in children with neurodevelopmental disability) in the Pediatrics Clinic of the University Clinical Center of Tuzla were retrospectively analyzed during 2008 in relation to seasonal distribution, admission time (month, week, admission moment, day in a week, time of the day) and the lunar cycle." | ( Hadzic, BC; Hadzic, D; Mladina, N; Numanovic, A, 2010) |
| "Clinical seizure remission within 10 min of drug administration was found in 80% of the intravenous group as compared to 83." | ( Arya, R; Gulati, S; Kabra, M; Kalra, V; Sahu, JK, 2011) |
| "We describe here how behavioural seizures can be triggered in adult zebrafish by the administration of kainate and are very similar to those observed in rodent models." | ( Alfaro, JM; Burgos, JS; Ripoll-Gómez, J, 2011) |
| "Acute seizures are readily recognizable episodes requiring urgent treatment." | ( Chen, YI; Chiang, LM; Chou, ML; Deng, ST; Hung, PC; Lin, KL; Shen, HH; Tseng, CH; Wang, HS, 2011) |
| "Seizures or seizure-like phenomena which are mostly convulsive have been observed during the induction, maintenance and withdrawal phases of propofol administration." | ( Abou-Khalil, B; Arain, A; Patton, T; Smithson, K; Sonmezturk, HH; Zubair, S, 2011) |
| "To assess clonic seizure threshold, pentylenetetrazole (PTZ) was administered intravenously." | ( Baradaran, N; Dehpour, AR; Dehpour, S; Kabiri, T; Moezi, L; Shafaroodi, H, 2011) |
| "An increase in seizure frequency subsequent to generic substitution was associated with polytherapy compared to monotherapy (3." | ( Chaluvadi, S; Chiang, S; Friedman, DE; Goldsmith, CE; Tran, L, 2011) |
| "In humans, melatonin may attenuate seizures, and it is most effective in the treatment of juvenile intractable epilepsy." | ( Banach, M; Borowicz, KK; Gurdziel, E; Jędrych, M, 2011) |
| "In 3 out of 13 rats, limbic convulsive seizures, which were not related to the time of drug administration, were observed after 5-8 days." | ( Perescis, MF; van Luijtelaar, G; van Rijn, CM; Vinogradova, L, 2011) |
| "Electrical stimulation to control seizures may be an additive therapy." | ( Besio, WG; Koka, K; Liu, X; Medvedev, AV; Wang, L, 2011) |
| "Neonatal stroke presents with seizures that are usually treated with phenobarbital." | ( Comi, AM; Johnston, MV; Kadam, SD; Markowitz, GJ; Smith, DR, 2011) |
| "He experienced convulsions from day 4 and was administered anticonvulsants." | ( Hagioka, S; Maeyama, H; Morimoto, N; Nagae, M; Naito, H; Okada, D; Okahara, S, 2011) |
| "Clinical data (including preoperative seizure history), radiological data, surgical treatment, antiepileptic treatment were retrospectively reviewed." | ( Ciccarino, P; d'Avella, D; Del Moro, G; Della Puppa, A; Denaro, L; Lombardi, G; Manara, R; Rossetto, M; Rotilio, A; Scienza, R, 2011) |
| "Here, we report three cases of seizures that developed after the administration of zoledronic acid." | ( Gruber, M; Hamann, C; Hofbauer, LC; Rachner, TD; Tsourdi, E; Ziemssen, T, 2011) |
| "After treatment with levetiracetam, seizures recurred and intravenous loading with valproic acid was administered, but resulted in a rapid increase in international normalized ratio (INR) to 7." | ( Giraldo, EA; Wijdicks, EF; Yoon, HW, 2011) |
| "Patients reported an increase in seizure activity to their neurologists after treatment was switched from Keppra to generic levetiracetam formulations." | ( Fitzgerald, CL; Jacobson, MP, 2011) |
| "The latency to the onset of the first seizure induced by PTZ was significantly increased by ICV administration of MgSO₄ at a dose of 100 µg compared to the control treatment." | ( Futuro Neto, Hde A; Nakamura-Palacios, EM; Oliveira, LD; Oliveira, RW, 2011) |
| "A by-treatment difference in incident seizures was not detected." | ( Boaz, M; Dabby, R; Gilad, R; Lampl, Y; Sadeh, M, 2011) |
| "LEV administrations in preseizure-manifesting SERs reduced the decrease of CA3 neurons and mossy fibers sprouting at 10-11 weeks of age in both group A and B." | ( Arita, K; Hanaya, R; Kumafuji, K; Kurisu, K; Sasa, M; Serikawa, T; Sugata, S; Tokudome, M, 2011) |
| "Three epileptic seizures occurred during anticonvulsive therapy in the LEV group, and two in the VPA group, including one non-convulsive status epilepticus (NCSE)." | ( Bjeljac, M; Keller, E; Mink, S; Muroi, C; Seule, M, 2011) |
| "End of seizure episode (clinically) was defined as cessation of visible epileptic phenomenon or return of purposeful response to external stimuli within 15 min of drug administration." | ( Gathwala, G; Goel, M; Mittal, K; Singh, J, 2012) |
| "In the latter rats, audiogenic running seizures reappeared for at least two weeks after the end of treatment." | ( Shatskova, AB; van Rijn, CM; Vinogradova, LV, 2011) |
| "However, generalized seizures occurred in a significantly lesser proportion of subjects in the treatment group (n = 3, 15." | ( Khandelwal, N; Lal, V; Medhi, B; Modi, M; Prabhakar, S; Singla, M, 2011) |
| "Demographic and seizure characteristics were similar in treatment and control groups." | ( de Souza, A; Kovoor, JM; Nalini, A; Siddalingaiah, HS; Thennarasu, K; Yeshraj, G, 2011) |
| "The frequency of prior seizure in flumazenil-treated patients was 30 times higher (8." | ( Cooper, G; Dyas, J; Routledge, PA; Thompson, JP; Veiraiah, A, 2012) |
| "Finally, we showed that kainate induced seizures and glycemia were not modified by spadin treatments." | ( Borsotto, M; Coppola, T; Gandin, C; Heurteaux, C; Labbal, F; Mazella, J; Moha Ou Maati, H; Veyssiere, J; Widmann, C, 2012) |
| "However, in those mice that do develop seizures, the pathological changes (neuronal cell loss, inflammation [perivascular cuffing, gliosis, activated microglia/macrophages]), and the numbers of virus infected cells in minocycline-treated or IL-6-deficient chimeric mice are very similar." | ( Fujinami, RS; Kennett, NJ; Libbey, JE; White, HS; Wilcox, KS, 2011) |
| "The mainstay of treatment for seizures is medical therapy with antiepileptic drugs." | ( Grant, R; Kerrigan, S, 2011) |
| "This seizure-suppressant effect of combination gene therapy with Y5 receptors and neuropeptide Y was significantly stronger as compared to neuropeptide Y overexpression alone." | ( Ängehagen, M; Christiansen, SH; Gøtzsche, CR; Kokaia, M; Nikitidou, L; Olesen, MV; Sørensen, AT; Sørensen, G; Woldbye, DP, 2012) |
| "CHV considerably enhanced the seizure activity leading to changes in clinically determined parameters of the treatment course: the necessity for increasing the electric charge, for re-stimulations (trend) and for bilateral stimulations was lower in the CHV group as compared to the UHV group." | ( Gillmann, B; Grözinger, M; Haeck, M; Janouschek, H, 2011) |
| "Levetiracetam also provided seizure control relative to placebo as adjunctive therapy in patients with idiopathic generalized epilepsy with myoclonic seizures or GTC seizures." | ( Lyseng-Williamson, KA, 2011) |
| "Efficacy results are reported for all seizure types [intention-to-treat (ITT) population, N = 217] and subpopulations with tonic-clonic (n = 152), myoclonic (n = 121), and/or absence (n = 70) seizures at baseline." | ( Delanty, N; Jones, J; Tonner, F, 2012) |
| "(1) they had more severe KA-induced seizures than apoE2 and 3 mice, (2) they exhibited neuron loss in hippocampus that was higher than in apoE2, 3 and WT mice, (3) KA administration resulted in higher counts of their head drops in the cross-area of elevated plus-maze, (4) they showed lower KA-induced rearing activity than apoE2 mice in the open-field test, (5) their KA-induced microglial expression of MHC-II and CD86 was elevated compared to apoE3 mice, (6) the KA-induced increase of microglial iNOS was higher than that in the other groups of mice, and (7) the TNF-α and IL-6 expression was decreased 7 days after KA application compared to untreated mice and mice treated 1 day with KA." | ( Adem, A; Mao, XJ; Mix, E; Pham, T; Winblad, B; Zhang, HL; Zhang, XM; Zheng, XY; Zhu, J, 2012) |
| "Midazolam was administered with seizure resolution." | ( Cole, JB; Gross, EA; Smith, SW; Stellpflug, SJ, 2011) |
| "In pilocarpine-induced seizures, the EUG-treated rats showed no shorter seizure latency but a lower seizure severity and mortality than the control rats." | ( Chow, JC; Huang, CW; Tsai, JJ; Wu, SN, 2012) |
| "Secondly, the number of seizures induced by pentylenetetrazole (PTZ) was quantified in rats following chronic sodium selenate treatment via drinking water." | ( Chen, T; Corcoran, NM; Grundy, R; Hovens, CM; Jones, NC; Nguyen, T; O'Brien, TJ; Velakoulis, D, 2012) |
| "Oxygen toxicity seizures (OTS) are a known complication of hyperbaric oxygen therapy (HBOT)." | ( Banham, ND, 2011) |
| "The median percent reduction in weekly seizure frequency over the treatment period was 59." | ( Cho, YW; Heo, K; Kim, KS; Kim, OJ; Kim, SE; Kim, SH; Lee, BI; Lee, JH; Lee, SJ; Park, SP; Shin, DJ; Song, HK; Yi, SD, 2012) |
| "MDR1 T allele carriers in the seizure reoccurrence (SR) group of GS and FS were high compared with the well-controlled seizure group (with no seizures after treatment)." | ( Bhiladvala, D; Chaudhari, JR; Das, UN; Hasan, Q; Jaleel, MA; Kaipa, PR; Ponnala, S, 2012) |
| "Therapy of seizure activity following exposure to the nerve agent soman (GD) includes treatment with the anticonvulsant diazepam (DZP), an allosteric modulator of γ-aminobutyric acid A (GABA(A)) receptors." | ( Kelley, NR; Lee, RB; Lumley, LA; Moffett, MC; Schultz, MK; Schwartz, JE; Stone, MF; Wright, LK, 2012) |
| "The CD₅₀ values for clonic and tonic seizures after oral administration were 0." | ( Banks, CN; Bruun, DA; Dhir, A; Hammock, BD; Inceoglu, B; Lein, PJ; McCoy, MR; Rogawski, MA; Sanborn, JR; Zolkowska, D, 2012) |
| "The enhanced anti-seizure and neuroprotective effect achieved by disruption of the A1R/neurabin/RGS4 complex is elicited by the on-site and on-demand release of endogenous adenosine, and does not require administration of A1R ligands." | ( Chen, Y; Cottingham, C; Greengard, P; Jiao, K; Liu, Y; McMahon, L; Wang, Q, 2012) |
| "Anti-seizure prophylaxis is routinely utilized during busulfan administration for HSCT." | ( Bajwa, RP; Gross, TG; Pai, V; Skeens, M; Soni, S; Termuhlen, AM, 2012) |
| "To determine the threshold for clonic seizures, PTZ was administered intravenously." | ( Adabi Mohazab, R; Dehpour, AR; Delfan, B; Javadi-Paydar, M, 2012) |
| "To investigate the frequency of seizures associated with acepromazine administration when used as a premedicant with methadone for dogs undergoing myelography." | ( Drynan, EA; Gray, P; Raisis, AL, 2012) |
| "She had an acute onset of a generalized seizure and coma on the fourth day after chemotherapy." | ( Chen, CH; Chen, JS; Cheng, CY; Deng, ST; Lin, YC, 2011) |
| "When tested at 3-9 weeks after seizure/control treatment, seizure as compared to control rats showed no difference in finding a hidden platform in the water maze, but were deficient in learning and maintaining consecutive criterion performance in the 8-arm radial arm maze." | ( Boon, F; Boyce, R; Cain, DP; Crutchley, M; Leung, LS; Ma, J; Tsai, ML, 2012) |
| "Adults with a history of seizure who used Dilantin Kapseals 100 mg extended phenytoin sodium, USP, capsules and whose therapy was interchanged to Taro Pharmaceuticals' AB-rated generic extended phenytoin sodium capsules, USP, 100 mg between July 2007 and May 2008 were included." | ( Bentley, WH; Delate, T; Kinikar, SA; Menaker-Wiener, CM, 2012) |
| "The individual time-course of the seizure threshold (ST) in electroconvulsive therapy is mostly unknown." | ( Hoyer, C; Janke, C; Kranaster, L; Lederbogen, F; Lewien, A; Sartorius, A, 2012) |
| "Innovative treatments of epileptic seizures are needed to improve the outcome of epilepsy." | ( Ikeda, H; Imai, K; Kubota, Y; Susa, F; Takahashi, Y; Yamazaki, E, 2013) |
| "Oxidative stress induced by seizures was also attenuated as indicated by significant increase in GSH and decrease in MDA levels in HEOM treated groups." | ( Kumar Gupta, Y; Mehla, J; Pahuja, M, 2012) |
| "In a kainic acid (KA)-induced seizure model in mice, hippocampal CA1 pyramidal cells undergo delayed neuronal death at day 3-4 following systemic KA administration." | ( Kinoshita, C; Kinoshita, Y; Morrison, RS; Schwartzkroin, PA; Wenzel, HJ, 2012) |
| "Current standard therapy for seizure prophylaxis in Neuro-surgical patients involves the use of Phenytoin (PHY)." | ( Ghauri, AA; Khan, AA; Shamim, MS; Zafar, SN, 2012) |
| "The results show enhancement of seizure severity with significant reduction in GABA levels upon PTX treatment that were reversed by its combination with sodium valproate." | ( Kamal, SM, 2012) |
| "We investigated the seizures induced by electroshock using increasing-current delivery in 3- or 4-week-old rats, and found that the threshold-current of tonic extensor seizures was elevated with age in weeks in the vehicle-treatment groups." | ( Kanda, T; Takizawa, F; Tamura, T; Yamada, K, 2012) |
| "The quantitative evaluation in the MES seizures after oral administration into rats showed that the most active were 1-[{4-(4-fluorophenyl)-piperazin-1-yl}-methyl]-3-(2-bromophenyl)-pyrrolidine-2,5-dione (14) with ED(50) of 7." | ( Kamiński, K; Obniska, J; Rzepka, S, 2012) |
| "In our patient, seizures immediately stopped upon initiation of vigabatrin treatment, and his development and neurological examination at one year are normal." | ( Fluss, J; Korff, CM; Picard, F; Vulliemoz, S, 2012) |
| "The frequency of seizures among acutely poisoned adults who are administered flumazenil has not been well established." | ( Cantrell, FL; Clark, RF; Kreshak, AA; Tomaszewski, CA, 2012) |
| "Total spike number and the generalized seizure duration were reduced in the carbenoxolone treated group compared to the PTZ group." | ( Acar, MD; Bagirici, F; Marangoz, C; Sefil, F, 2012) |
| "On the contrary, we observed seizures and mortality in fluoxetine-treated Ts65Dn mice, raising the possibility of a drug × genotype interaction with respect to these adverse treatment outcomes." | ( Ehninger, D; Heinen, M; Hettich, MM; Paesler, K; Ryan, DP; Schnell, S, 2012) |
| "In addition, the convulsion onset time was significantly delayed by apigenin administration." | ( Ahn, SY; Han, JY; Hong, JT; Kim, CS; Kim, HC; Kim, SK; Oh, KW; Yoo, SK, 2012) |
| "The only seizure test where short-term rapamycin treatment protected mice was against tonic hindlimb extension in the MES threshold test, though this protection waned with longer rapamycin treatment." | ( Dolce, A; Hardwick, JM; Hartman, AL; Santos, P, 2012) |
| "In the flurothyl seizure model only the 4-h pretreatment with RAP was anticonvulsant in the both age groups." | ( Chachua, T; DeSantis, K; Nesheiwat, L; Poon, KL; Velíšek, L; Velíšková, J; Yum, MS, 2012) |
| "Five minutes after initiation of convulsions, MGS, CRM, or MDZ were administered." | ( Bloch-Shilderman, E; Brandeis, R; Egoz, I; Grauer, E; Katalan, S; Lazar, S; Rabinovitz, I; Raveh, L, 2013) |
| "In order to analyze the dynamics of seizure-induced elemental changes, the samples taken from seizure-experiencing animals 3 h and 1, 4, and 7 days after proconvulsive agent administration were analyzed." | ( Appel, K; Chwiej, J; Gzielo-Jurek, K; Janeczko, K; Kutorasinska, J; Setkowicz, Z; Simon, R; Uram, L, 2012) |
| "The SE incidence, SE latency and seizure severity as well as mortality were significantly reduced after treatment with a-asarone at different doses." | ( Chen, QX; Li, C; Li, XW; Miao, JK; Wu, XM; Zhang, XP, 2013) |
| "A 54-year-old Asian man developed seizure activity requiring emergent intubation during his initial cetuximab infusion for the treatment of metastatic colorectal cancer." | ( Bell, WA; McClellan, NH, 2012) |
| "Drug-induced seizures are in view of a constantly ageing population and increasingly frequent polypharmacotherapy an increasing problem in daily routine praxis." | ( Block, F; Dafotakis, M, 2013) |
| "At P40, KA-induced seizures and neuronal loss were significantly diminished in rats previously treated with LEV." | ( Chang, M; Fitzgerald, E; Folkerth, RD; Jensen, FE; Kosaras, B; Murphy, A; Talos, DM, 2013) |
| "During convulsions, Zn treatment did not show any protective effect on BBB permeability." | ( Demir, G; Oztaş, B; Seker, FB; Yalçın, IE; Yorulmaz, H, 2013) |
| "Furthermore, the reduced seizure and excitotoxicity and normal spatial learning exhibited in TRPC5 KO mice suggest that TRPC5 is a promising novel molecular target for new therapy." | ( Abramowitz, J; Birnbaumer, L; Flockerzi, V; Freichel, M; Gottschall, PE; Howell, MD; Phelan, KD; Rhee, SW; Shwe, UT; Wu, H; Zheng, F, 2013) |
| "The reduction in seizure count was also evident following insulin induced hypoglycemia with the triheptanoin treated group having significantly less SWDs than control animals under similar low blood glucose conditions." | ( Borges, K; Kim, TH; Petrou, S; Reid, CA, 2013) |
| "We examined the seizure susceptibility of these mice to determine if the presence (BXD29-Trl4(lps-2J)/J) or absence (C57BL/10J) of p-ACC, in strains with MCD, confers a differential response to chemi-convulsive treatment." | ( Gabel, LA; Ibanez, N; Manglani, M; Ramos, RL; Roberts, J; Rosen, GD, 2013) |
| "Neonatal seizures can lead to later life epilepsy and neurobehavioral deficits, and there are no treatments to prevent these sequelae." | ( Fitzgerald, EF; Huganir, RL; Hunganir, RL; Jensen, FE; Klein, PM; Rakhade, SN; Sun, H; Zhou, C, 2012) |
| "The patients who had a single seizure at the time of consultation were, in principle, followed without any treatment, and those with repeated seizures were treated with intravenous injection of 10 mg/kg PB." | ( Ban, H; Takami, Y, 2012) |
| "PB was administered after a single seizure in one patient, and the remainder were treated after 2-7 seizures, no patient had repeated seizures." | ( Ban, H; Takami, Y, 2012) |
| "Further, E-64d-pretreated seizure rats (EXP2) showed a significant downregulation of mRNA expression of PRG-1, PRG-3 and PRG-5, cathepsin B and ApoE, as well as up-regulated nSMase and ANX7 in hippocampus when compared with EXP1 rats." | ( Feng, X; Ni, H; Ren, SY; Sun, Q; Tian, T; Zhang, LL, 2013) |
| "Pilocarpine-induced seizure increased p47 immunofluorescence in the plasma membrane of hippocampal neurons at 12h post-insult and apocynin treatment prevented this increase." | ( Choi, BY; Choi, HC; Chung, TN; Jang, BG; Kim, HS; Kim, JH; Sohn, M; Song, HK; Suh, SW, 2013) |
| "Aminoguanidine increased the initial seizure and latency until death, and administration of 1400W did not have an effect." | ( Cavalcante Melo, FH; de Carvalho Lima, CN; de França Fonteles, MM; Freire Vasconcelos, L; Leite Dias, M; Moura Rocha, NF; Rodrigues Carvalho, AM; Soares Lopes, K; Vasconcelos Rios, ER, 2013) |
| "When (sub)clinical seizures are treated, there is no consensus about the most appropriate treatment for neonatal seizures and how to assess the efficacy of treatment." | ( de Vries, LS; Hellström-Westas, L; van Rooij, LG, 2013) |
| "We pretreated mice with MG before seizure induction with picrotoxin or pilocarpine and then assessed seizures behaviorally or by electroencephalography (EEG)." | ( Distler, MG; Escayg, A; Gorfinkle, N; Palmer, AA; Papale, LA; Termini, J; Winawer, MR; Wuenschell, GE, 2013) |
| "This case documents a generalized tonic-clonic seizure in a 15-year-old girl after receiving 60 mg of methohexital and numerous prior episodes of bitemporal electroconvulsive therapy." | ( Rasmussen, KG; Swintak, CC; Vande Voort, JL; Wall, CA, 2013) |
| "Although antiseizure medication is the first-line treatment for epilepsy, currently available medications are ineffective in a significant percentage of patients and have not clearly been demonstrated to have disease-specific effects for epilepsy." | ( McDaniel, SS; Rensing, NR; Wong, M; Zhang, B, 2013) |
| "ESX treatment significantly reduced seizures in GAERS during the treatment phase, and this effect was maintained during the 12-week posttreatment phase (p < 0." | ( Blumenfeld, H; Dezsi, G; Jones, NC; O'Brien, TJ; Ozturk, E; Powell, KL; Stanic, D, 2013) |
| "Thirteen of 14 children became seizure-free with treatment." | ( Agostinelli, S; Capovilla, G; Chiarelli, F; Coppola, G; Curatolo, P; Foiadelli, T; Grosso, S; Parisi, P; Prezioso, G; Romeo, A; Savasta, S; Spalice, A; Striano, P; Verrotti, A, 2013) |
| "Neonates whose seizures were not controlled by the assigned drug were then crossed over to be treated with other drug in same dose." | ( Chawla, D; Goel, SP; Pathak, G; Pathak, U; Upadhyay, A, 2013) |
| "During the follow-up study, the seizure severity increased in animals treated with 0." | ( Firoozabadi, SM; Javan, M; Mirnajafi-Zadeh, J; Mongabadi, S; Shojaei, A, 2013) |
| "We examined seizure activity on the real time and amplitude integrated EEG records of 14 full-term infants with perinatal asphyxial encephalopathy treated within 12 h of birth with 30% inhaled xenon for 24 h combined with 72 h of moderate systemic hypothermia." | ( Azzopardi, D; Edwards, AD; Griffiths, J; Kapetanakis, A; Mathieson, SR; Rennie, JM; Robertson, NJ, 2013) |
| "In addition, the seizures resulted in up-regulation of Drp1 expression and mdivi-1 treatment had no effect on the expression." | ( Lian, Y; Wang, C; Wu, C; Xie, N; Zhang, H; Zhang, Q, 2013) |
| "The treatment of neonatal seizures has not changed significantly over the last 50 years despite advances in antiepileptic drug (AED) development for older children and adults." | ( Mangum, B; Pressler, RM, 2013) |
| "We present a female with seizures one month after delivery who had borderline elevated liver enzymes prior to the initiation of OXC treatment." | ( Bielen, A; Bielen, I; Marusić, M; Planjar-Prvan, M; Sruk, A, 2013) |
| "Cefepime or meropenem-associated convulsions were defined according to the following criteria: (1) administration or dose escalation of diazepam, phenytoin, phenobarbital and thiamylal given via the intravenous route (2) convulsions recorded in medical records during administration of cefepime or meropenem." | ( Araki, H; Suemaru, K; Takechi, K; Tanaka, A; Tanaka, M; Watanabe, S, 2013) |
| "The prevalence of convulsions was significantly greater in the cefepime treated group than in the meropenem-treated group." | ( Araki, H; Suemaru, K; Takechi, K; Tanaka, A; Tanaka, M; Watanabe, S, 2013) |
| "Treatment of neonatal seizures still relies primarily on phenobarbital, despite an estimated efficacy of less than 50% and concern over neurodegenerative side effects." | ( Ågren, J; Flink, R; Hellström-Westas, L; Lundqvist, M; Wickström, R, 2013) |
| "Twenty-two patients developed convulsions, which was the most common complication during therapy." | ( Alaygut, D; Bolat, F; Cevit, Ö; Doğan, MT; Gültekin, A; Güven, AS; Içağasoğlu, FD; Oflaz, MB; Özdemir, G, 2013) |
| "To analyze seizure control, dose adjustments, and other changes of antiepileptic drug (AED) treatment during pregnancy in a large cohort of women with epilepsy entering pregnancy on monotherapy with carbamazepine, lamotrigine, phenobarbital, or valproate." | ( Battino, D; Bonizzoni, E; Craig, J; Lindhout, D; Perucca, E; Sabers, A; Tomson, T; Vajda, F, 2013) |
| "Data collected included overall seizure frequency, frequency of prolonged seizures, and use of rescue medications and emergency room (ER)/hospital visits in the year preceding stiripentol initiation, and with stiripentol therapy." | ( Chancharme, L; Chugani, H; de Menezes, MS; Devinsky, O; Franz, DN; Hamiwka, L; Hernandez, A; Laux, L; Le Guern, ME; Mikati, MA; Morse, RP; Saneto, RP; Sullivan, J; Valencia, I; Wirrell, EC, 2013) |
| "AEA and WIN both reduced absence seizures independently from the brain focal site of infusion while, conversely, rimonabant increased absence seizures but only when focally administered to the ventroposteromedial thalamic nucleus (VPM)." | ( Calignano, A; Citraro, R; De Sarro, G; Ngomba, RT; Nicoletti, F; Russo, E; Scicchitano, F; Whalley, BJ, 2013) |
| "Sublingual lorazepam stopped seizures within 10 minutes of administration in 56% of children compared with intrarectal diazepam in 79% (P < ." | ( Dubru, JM; Kahamba, DM; Kokolomani, J; Malu, CK; Mayamba, RM; Misson, JP; Mukampunga, C; Musalu, EM; Walker, TD; Wilmshurst, JM, 2014) |
| "Hypothermia reduced seizure burden during and after treatment in all cases." | ( Buttram, S; Guilliams, K; Miller, B; Pineda, J; Rosen, M; Shoykhet, M; Zempel, J, 2013) |
| "Handling-evoked and spontaneous convulsive seizures were observed in many BoNT/B-treated animals but not in vehicle-treated controls." | ( Bröer, S; Gernert, M; Rogawski, MA; Zolkowska, D, 2013) |
| "Optimal treatment of seizures in AS remains undetermined." | ( Gurnett, CA; Kasasbeh, AS; Smyth, MD, 2014) |
| "The most favorable seizure outcome was seen in a patient with partial agenesis of the corpus callosum treated with CC." | ( Gurnett, CA; Kasasbeh, AS; Smyth, MD, 2014) |
| "Understanding how seizures spread throughout the brain is an important problem in the treatment of epilepsy, especially for implantable devices that aim to avert focal seizures before they spread to, and overwhelm, the rest of the brain." | ( Hall, D; Kuhlmann, L, 2013) |
| "To provide two-year seizure and neuropsychological outcomes in patients treated by stereotactic radiofrequency amygdalohippocampectomy (SAHE), an alternative, minimally invasive method for the treatment of mesial temporal lobe epilepsy (MTLE)." | ( Kramska, L; Liscak, R; Lukavsky, J; Malikova, H; Vojtech, Z, 2013) |
| "Valproate treatment suppressed seizures by 80% in GAERS (p<0." | ( Dedeurwaerdere, S; Elms, J; Morris, MJ; O'Brien, TJ; Powell, KL; van Raay, L, 2013) |
| "Recently, seizures in dogs have been proposed as a translational platform for human therapeutic trials on new epilepsy treatments." | ( Hoffmann, K; Löscher, W; Potschka, H; Töllner, K; Twele, F, 2013) |
| "FTA significantly increased the seizure latency and decreased the mortality in PTZ-treated mice." | ( Cui, R; Li, B; Li, Y; Liu, L; Song, Y; Tang, F; Wang, L; Wang, Y; Zhao, J; Zhou, Y, 2013) |
| "The precise metabolic cause of the seizures remains unknown and pyridoxine treatment apparently does not cure the epilepsy." | ( Abeling, NGGM; Bosch, AM; Cobben, JM; de Roo, MGA; Duran, M; Koelman, JHTM; Majoie, CB; Poll-The, BT, 2014) |
| "The treatment profile for epilepsy, seizure control, and maternal and neonatal outcomes in both groups were compared using Chi-square test or Fisher's exact test and Mann-Whitney U test." | ( Abe, K; Hamada, H; Minakami, H; Obata-Yasuoka, M; Yamada, T; Yoshikawa, H, 2014) |
| "Although seizures have been reported in interferon-treated patients with multiple sclerosis and in a variety of malignancies, the epileptogenic potential of interferon-α in the treatment of HCV infection is considered minimal." | ( Antinori, S; Cattaneo, D; Falvella, FS; Gervasoni, C; Magni, C; Milazzo, L; Peri, AM; Vidale, S, 2013) |
| "Hence, seizure prophylaxis is routinely utilized during BU administration for stem cell transplantation (SCT)." | ( Aricò, M; Caselli, D; Cesaro, S; Cicalese, MP; Faraci, M; Lo Nigro, L; Locatelli, F; Longoni, D; Maximova, N; Menconi, MC; Nesi, F; Paolicchi, O; Podda, M; Prete, A; Ripaldi, M; Rosati, A; Santarone, S; Ziino, O, 2014) |
| "Neonatal seizures are often refractory to treatment with initial antiseizure medications." | ( Ariguloglu, EA; Koklu, E; Koklu, S, 2014) |
| "There was a tendency towards lower seizure rate in the O2-treated group at one month after pilocarpine-induced SE." | ( Groeneweg, L; Kirschstein, T; Köhling, R; Müller, L; Müller, S; Sellmann, T; Tokay, T, 2014) |
| "Six patients had no prior history of seizures, and 1 patient with a prior history was not taking AED therapy at the time of presentation." | ( Beran, RG; Cordato, DJ; Malkan, A; Patel, V, 2014) |
| "Thirteen cats had no additional seizures after initiation of PB treatment." | ( Barnes Heller, HL; Finnerty, KE; Giovanella, CJ; Lau, VW; Mercier, MN; Rylander, H, 2014) |
| "However, the effects of the seizures, as well as possible treatment strategies, have yet to be elucidated, particularly in juvenile or insulin-dependent diabetes mellitus (IDDM)." | ( Carlen, PL; del Campo, M; El-Hayek, Y; Giacca, A; Hazrati, L; Maheandiran, M; Mylvaganam, S; Sugumar, S; Wu, C; Zhang, L, 2013) |
| "Metabolic encephalopathy in the form of seizures can result from many inborn errors of metabolism and considering the large number of disorders causing metabolic encephalopathy, enzyme assays or conventional molecular tests are expensive and take considerably long period of time which results in delayed treatment." | ( Adıyaman, G; Biberoğlu, G; Çiftci, B; Ezgu, F; Gökmenoğlu, H; Hasanoğlu, A; Kasapkara, Ç; Küçükçongar, A; Topçu, B; Tümer, L, 2014) |
| "Latency and probability of PTZ-induced seizures were shorter and higher respectively, in hyperthermia-treated animals compared to controls." | ( Abdeen, Z; Al Shawaaf, F; Al-Ansari, S; Alsaffar, Y; Hassan, Z; Kamal, A; Mandeel, M; Rajab, E, 2014) |
| "However, the treatment of some seizure types and novel drug formulations deserve further advances in epilepsy research." | ( Citraro, R; De Sarro, G; Franco, V; Grillo, E; Iudice, A; Russo, E, 2014) |
| "We therefore conclude that a seizure reduction of >50% following dietary treatment is not a suitable criterion for identifying patients with GLUT1-DS, as these patients generally achieve complete seizure freedom shortly after diet initiation." | ( Haavardsholm, KC; Nakken, KO; Ramm-Pettersen, A; Selmer, KK, 2014) |
| "It was found that seizures, tachycardia, nerve damage, clinical symptoms, brain injuries and mortality induced by such lethal toxin were effectively prevented by the prophylactic patch treatment up to certain LD50 level." | ( Banerjee, S; Chattopadhyay, P; Ghosh, A; Gogoi, J; Pathak, MP; Veer, V, 2014) |
| "Repeated treatment with electroconvulsive seizure (ECS) induces changes in histone acetylation, expression of various genes, and intrabrain cellular changes, including neurogenesis." | ( Ahn, YM; Kim, SH; Kim, YS; Park, HG; Park, S; Yu, HS, 2014) |
| "All the seizure parameters were significantly reduced when phenobarbital (3 mg/kg) was administered prior to the application of the non-effective pattern of LFS." | ( Asgari, A; Atapour, N; Mirnajafi-Zadeh, J; Moradi, H; Semnanian, S; Shojaei, A, 2014) |
| "The brain seizure, not the method of induction, is the essential element in the efficacy of convulsive therapy." | ( Fink, M, 2014) |
| "Mean seizure severity and cumulative seizure duration proved to be comparable between vehicle- and L-701,324-treated mice." | ( Aronica, E; Gorter, J; Potschka, H; Salvamoser, JD; Soerensen, J; van Vliet, EA; Zellinger, C, 2014) |
| "Current treatments for seizure emergencies, such as status epilepticus, include intravenous or rectal administration of benzodiazepines." | ( Georg, GI; Kapoor, M; Lis, L; Siegel, RA; Winter, T, 2014) |
| "Severe metabolic acidosis and seizure have been described, but the use of renal replacement therapy has not been studied in the context of overdose." | ( Al-Abri, SA; Anderson, IB; Colby, JM; Olson, KR; Pedram, F, 2015) |
| "Despite reports of seizures, coma, and death associated with its use as well as banning of its environmental use by the Environmental Protection Agency (EPA), the US Food and Drug Administration (FDA) still allows treatment with lindane as a second-line scabicide and pediculicide." | ( Kelley, M; Olson, KR; Russell, JL; Walson, PD; Wiles, DA, 2015) |
| "We have reported significantly higher convulsion prevalence in patients treated with cefepime than in those treated with meropenem." | ( Araki, H; Suemaru, K; Takechi, K; Tanaka, A; Tanaka, M; Watanabe, S, 2014) |
| "In addition to seizure suppression in vivo, GS967 treatment greatly improved the survival of Scn2a(Q54) mice, prevented hilar neuron loss, and suppressed the development of hippocampal mossy fiber sprouting." | ( Anderson, LL; Bush, WS; Frankel, WN; George, AL; Hawkins, NA; Kearney, JA; Nath, RD; Petersohn, AA; Rajamani, S; Thompson, CH; Vanoye, CG, 2014) |
| "On admission, he redeveloped convulsions and loading doses of phenytoin, phenobarbitone and midazolam were administered." | ( David, HS; Rajavelu, KK; Sampath, S; Sivathanu, S, 2014) |
| "In this KA-induced seizure model, the systemic administration of GL 30 min before KA administration significantly suppressed neuronal cell death and markedly suppressed gliosis and proinflammatory marker inductions." | ( Jin, Y; Kim, ID; Lee, JK; Luo, L, 2014) |
| "Pretreatment with stansin 6 inhibited convulsions in rats from kainic acid-induced seizures, reduced the degeneration pattern in the CA3 region, decreased astrocytic reactivity, and reduced the expression of IL-1β and TNF-α induced by kainic acid." | ( Aguilar-Guadarrama, B; Aguirre-Moreno, A; Campos-Peña, V; Castillo-España, P; Estrada-Soto, S; León-Rivera, I; Navarrete-Vázquez, G; Rios, MY; Rivera-Leyva, JC; Villeda-Hernández, J, 2014) |
| "Psychogenic nonepileptic seizures, the most common conversion disorder, are as disabling as epilepsy and are not adequately addressed or treated by mental health clinicians." | ( Baird, GL; Barry, JJ; Blum, AS; Frank Webb, A; Keitner, GI; LaFrance, WC; Machan, JT; Miller, I; Szaflarski, JP, 2014) |
| "Five patients became seizure-free on LCM monotherapy following withdrawal of their initial treatment." | ( Brodie, MJ; Kelly, K; Parker, P; Stephen, LJ, 2014) |
| "torvum leaves is used to treat epileptic seizures." | ( Bock, M; Buenafe, OE; Challal, S; Crawford, AD; Dayrit, FM; de Witte, PA; Esguerra, CV; Harvey, AL; Kloeti, W; Lerche, H; Maljevic, S; Marcourt, L; Queiroz, EF; Wolfender, JL, 2014) |
| "Here, we evaluated various behavioral seizure abnormalities in neonatal rats (Sprague-Dawley; postnatal day 9) after an intraperitoneal administration of NMDA." | ( Chopra, K; Dhir, A, 2015) |
| "In another experiment, seizure threshold with tramadol was investigated in rats intracerebroventricularly administered with either a serotonin receptor antagonist (methysergide) or saline (n = 6)." | ( Fujimoto, Y; Funao, T; Mori, T; Nishikawa, K; Suehiro, K; Takahashi, R, 2015) |
| "Pretreatment significantly affected seizure threshold and serotonin fluctuations." | ( Fujimoto, Y; Funao, T; Mori, T; Nishikawa, K; Suehiro, K; Takahashi, R, 2015) |
| "Although a rational time-frame of seizure prophylactic treatment with LEV for after TBI is not well established, clinical prophylaxis with LEV often includes treatment duration similar to clinical treatment guidelines with Phenytoin." | ( Fowler, L; Hurwitz, M; Wagner, AK; Zou, H, 2015) |
| "Animals with spontaneous recurrent seizures induced by pilocarpine administration were implanted with movable microelectrodes in the right anterior and posterior hippocampus to evaluate the effects of gap junction blockers administered in the entorhinal cortex." | ( Medina-Ceja, L; Ventura-Mejía, C, 2014) |
| "Thirty minutes of seizure activity is usually the time period used in longstanding definitions of CSE but it is not acceptable to wait for 30 minutes before treatment." | ( Chin, RF, 2014) |
| "Finally, using multiple in vivo seizure models, we identify potent lead candidates for the treatment of epilepsy." | ( Cano-Jaimez, M; Chang, P; Close, AJ; McEvoy, JP; Spencer, J; Walker, MC; Williams, RS; Williams, S; Zuckermann, AM, 2015) |
| "After adjustment for seizure burden, neonates managed during the Neonatal Neurocritical Care Service era, on average, received 30 mg/kg less cumulative phenobarbital (95% confidence interval 15-46 mg/kg) and were on maintenance 5 fewer days (95% confidence interval 3-8 days) than those who were treated prior to implementation of the service." | ( Bonifacio, SL; Glass, HC; Kuzniewicz, MW; McCulloch, CE; Wietstock, SO, 2015) |
| "A patient presented with convulsive seizures when sodium valproate (VPA) and tebipenem pivoxil (Orapenem) were co-administered accidentally." | ( Miki, A; Nakamoto, N; Satoh, H; Sawada, Y; Shihyakugari, A, 2015) |
| "He experienced convulsive seizures the day after beginning co-administration." | ( Miki, A; Nakamoto, N; Satoh, H; Sawada, Y; Shihyakugari, A, 2015) |
| "The ESES phenomenon and seizures were observed before and after treatment." | ( Bao, X; Chang, X; Chen, J; Fu, N; Ji, T; Jiang, Y; Liu, X; Qin, J; Wang, S; Wu, Y; Xiong, H; Yang, Z; Zhang, Y, 2014) |
| "Both medication were effective for seizure control and no significant difference was found between successful treatments after administering the medication (P = 0." | ( Azizi Malamiri, R; Fayezi, A; Jafari, M; Maraghi, E; Momen, AA; Nikkhah, A; Riahi, K, 2015) |
| "The 6 Hz model of focal seizures has been increasingly used to identify anticonvulsant compounds with potential activity against therapy-resistant epilepsy, but the protective response to anticonvulsants in this model could be dependent on experimental conditions and selection of mouse strains." | ( Kaminski, RM; Leclercq, K, 2015) |
| "Because seizures reappeared during tapering the dosage of PB, potassium bromide (KBr) at a daily dose of 80 mg/kg was additionally administrated." | ( Aiba, H; Okumura, Y; Watanabe, S, 2014) |
| "Although inactive in acute seizure tests, repeated administration of SAR127303 delays the acquisition and decreases kindled seizures in mice, indicating that the drug slows down epileptogenesis, a finding deserving further investigation to evaluate the potential of MAGL inhibitors as antiepileptics." | ( Arlt, H; Augé, F; Avenet, P; Beeské, S; Bergis, OE; Bert, L; Bertrand, T; Brittain, S; Didier, M; Escoubet, J; Even, L; Françon, D; George, P; Griebel, G; He, T; Houtmann, J; Jacquet, A; Leroy, T; Lopez-Grancha, M; Menet, V; Michot, N; Mikol, V; Pichat, P; Rak, A; Redon, N; Sun, F; Tolstykh, T; Vallée, F; Wiederschain, D; Yu, Q; Zhang, B, 2015) |
| "PTZ-kindled mice showed high seizure activity, hippocampal neuronal loss, and expression of growth-associated phosphoprotein (GAP-43) compared with saline-treated mice." | ( Alhaj, MW; Moustafa, YM; Zaitone, SA, 2015) |
| "PTZ administration induces absence-seizures at low dose, and generalised convulsive seizures at higher dose." | ( Anderson, P; Argyropoulos, A; Hannan, AJ; Hill-Yardin, EL; Hosie, S; O'Brien, TJ; Rind, G, 2015) |
| "The reported cases achieved control of seizures with adjunctive LCM treatment and were afterwards converted to monotherapy." | ( Papacostas, SS, 2015) |
| "Only 29% of LEV-treated animals had seizures compared to all controls following a latent period that was similar in duration." | ( Avoli, M; Behr, C; Lévesque, M, 2015) |
| "There was no apparent change of the seizure initiation pattern when kainic acid was coadministrated with AM404, URB597 or AM251." | ( Aliev, R; Kitchigina, V; Shubina, L, 2015) |
| "Post-traumatic seizures can exacerbate injurious outcomes of severe brain trauma, yet effective treatments are limited owing to the complexity of the pathology underlying the concomitant occurrence of both events." | ( Bridson, GW; Chen, Z; Graham, PB; Leung, LY; Lu, XC; Shear, DA; Tortella, FC; Uttamsingh, V, 2015) |
| "Treatment-resistant seizures affect about a third of patients suffering from epilepsy." | ( Afrikanova, T; Buenafe, OE; Crawford, AD; De Prins, A; de Witte, PA; Esguerra, CV; Kaminski, RM; Langlois, M; Leclercq, K; Rospo, CC; Smolders, I; Van Eeckhaut, A, 2015) |
| "Food intake triggers convulsions in fasted BALB/c mice and Wistar albino rats treated with antimuscarinic drugs, scopolamine or atropine." | ( Çağla, B; Enginar, N; Nurten, A; Türkmen, AZ, 2015) |
| "LF was administrated 7 d before seizure induction (pre-treatment) or 24 h after seizure induction (post-treatment) for 7 d." | ( Chen, DJ; Liu, FR; Liu, JX; Wang, YZ; Xie, QM; Yang, XJ; Zeng, LH, 2015) |
| "We report a case of isoniazid induced convulsions in 35 years old male alcoholic and smoker patient receiving intensive phase therapy for pulmonary tuberculosis." | ( Aiwale, AS; Barvaliya, MJ; Jha, PR; Patel, UA; Tripathi, C, 2015) |
| "Ethosuximide (250 mg/kg) reduced seizure severity in mice undergoing ethanol withdrawal with concurrent PTZ treatment (20 mg/kg)." | ( Godwin, DW; Masicampo, ML; Riegle, MA; Shan, HQ; Xu, V, 2015) |
| "However, the incidence of seizures induced by pentylenetetrazole significantly decreased in the groups administered systematically with 40 and 80 mg/kg of mefloquine." | ( Ballesteros-Zebadúa, P; Franco-Pérez, J; Manjarrez-Marmolejo, J, 2015) |
| "Furthermore, the melatonin-pretreated seizure rats (Mel + RS) exhibited a significantly upregulated expression of calcium/calmodulin-dependent protein kinase II α (CaMKIIα), acetyl-Coenzyme A acetyltransferase 1 (ACAT1), ZnT-1, metallothionein 1 (MT-1), nSMase and Cathepsin-E, compared with the RS rats." | ( Feng, X; Ni, H; Sun, BL; Sun, Q; Tian, T, 2015) |
| "Anti-seizure drugs are the most commonly employed treatment option for epilepsy and these generally provide effective management of seizures." | ( Pilitsis, JG; Shin, DS; Smith, AB; Yu, W, 2015) |
| "Most seizure emergencies occur outside of the hospital, and there is a need for treatment interventions that can be administered quickly and safely by nonclinical caregivers." | ( Kälviäinen, R, 2015) |
| "The threshold for seizure induction with progressive intravenous infusion of pentylenetrazole (PTZ) was evaluated in anesthetized Wistar rats two hours after a single 1 ml intragastric administration of BD-AcAc2 (i." | ( Arnold, P; Coppola, G; D'Agostino, D; Monda, M; Pilla, R; Viggiano, A, 2015) |
| "She experienced seizures on the third day of her hospitalization and was treated with anticonvulsant drugs." | ( Afroze, F; Ahmed, T; Chisti, MJ; Das, SK; Faruque, AS; Huq, S; Islam, MM; Matin, FB; Sarker, SA; Shahrin, L, 2015) |
| "In most cases, either the seizure or the medications used to treat the seizure may contribute to cognitive and psychosocial difficulties of various degrees of severity." | ( Blakeley, J; Piotrowski, AF, 2015) |
| "Evaluation for reversible causes of seizure activity along with anticonvulsant administration is generally the standard of care for breakthrough seizures." | ( Dewberry, RG; Pula, T; Vasagar, B; Verma, BR, 2015) |
| "How aggressively these seizures should be treated is unclear." | ( Husain, AM, 2015) |
| "The median time after EEG seizure onset before administration of in-MDZ was 2." | ( Bauer, S; Belke, M; Fründ, D; Kay, L; Knake, S; Reif, PS; Rosenow, F; Strzelczyk, A, 2015) |
| "Thirty mice that developed seizures were randomly divided into three groups and administered PHT as well as the following treatments: saline (negative control); verapamil (20 mg/kg, positive control); and G." | ( Chen, SL; Fan, Q; Ma, H; Zhang, C, 2015) |
| "Epilepsy is a highly prevalent seizure disorder which tends to progress in severity and become refractory to treatment." | ( Akula, KK; Boison, D; Coffman, SQ; Lusardi, TA; Masino, SA; Ruskin, DN, 2015) |
| "Importantly, chronic seizures in the mouse model of TLE were robustly suppressed by systemic administration of the GlyT1 inhibitor LY2365109." | ( Aronica, E; Boison, D; Bright, KA; Gorter, J; Hanthorn, M; Lytle, NK; Shen, HY; van Vliet, EA, 2015) |
| "In a kainate-induced murine seizure model, administration of a dose of an M-channel inhibitor that did not affect kainate-induced seizure transiently eliminated the anticonvulsant effects of VPA." | ( Greene, DL; Hoshi, N; Kang, S; Kay, HY; Kosenko, A, 2015) |
| "In a seizure model where mice received intracerebellar kainic acid injections, Houttuyniae Herba water extract treatment resulted in a lower seizure stage score, ameliorated cognitive impairment, protected neuronal cells against kainic acid-induced toxicity, and suppressed neuronal degeneration in the hippocampus." | ( Hong, SI; Jeong, HU; Kim, HG; Oh, MS, 2015) |
| "The results of seizure scoring and histopathological findings in the hippocampus revealed a more pronounced response to the same administered TMT dose in juvenile mice, compared with that in adult mice." | ( Im, HI; Kang, S; Kim, J; Kim, JC; Kim, SH; Lee, S; Moon, C; Park, K; Shin, T; Son, Y; Takayama, C; Yang, M, 2015) |
| "Evidence regarding symptomatic seizures from fluoroquinolones only relies on case reports and case series with most reports for ciprofloxacin in patients with renal dysfunction, mental disorders, prior seizures, or coadministered theophylline." | ( Rüegg, S; Sutter, R; Tschudin-Sutter, S, 2015) |
| "All of the patients remained seizure-free during levetiracetam treatment." | ( Chen, CL; Chen, NC; Chuang, YC; Lin, CH; Lin, TK; Tsai, MH, 2015) |
| "Acute seizures were treated with intranasal midazolam." | ( Heimans, JJ; Koekkoek, JA; Postma, TJ; Reijneveld, JC; Taphoorn, MJ, 2016) |
| "Maternal separation increased the seizure threshold, and administration of anticonvulsant/proconvulsant doses of morphine (1 and 30 mg/kg, respectively) reversed the impact of MS." | ( Alijanpour, S; Amini-Khoei, H; Amiri, S; Dehpour, AR; Haj-Mirzaian, A; Hassanipour, M; Mehr, SE; Mohammadi-Asl, A; Rahimi-Balaei, M; Shirzadian, A, 2015) |
| "Sleep architecture and seizures were assessed using continuous video-electroencephalography-electromyography recordings in Kcna1-null mice treated with vehicle or the dual orexin receptor antagonist, almorexant (100 mg/kg, intraperitoneally)." | ( Johnson, C; Matthews, SA; Roundtree, HM; Samson, KK; Simeone, KA; Simeone, TA, 2016) |
| "The risk of seizure recurrence with six months treatment compared with 12 to 24 months treatment was not statistically significant (odds ratio (OR) 1." | ( Mathew, A; Sharma, M; Singh, T, 2015) |
| "For those presenting with seizures, there is no reliable evidence regarding the duration of treatment required." | ( Mathew, A; Sharma, M; Singh, T, 2015) |
| "Using the maximal electroshock seizure (MES) as a model of tonic-clonic generalized seizures, we report that mice treated with TTA-A2 (0." | ( Chemin, J; Forichon, L; Françon, D; Gangarossa, G; Lerat, B; Lerner-Natoli, M; Lory, P; Sakkaki, S; Valjent, E, 2016) |
| "In the two animal models of seizures, the pretreatment of the IF (25, 50 and 75 mg/kg) with flumazenil blocked the anticonvulsant effect, suggesting that the mechanism of action of this ester derived of ferulic acid may be related to activity in the benzodiazepine-binding site of the GABAA receptor (γ-aminobutyric acid, type A)." | ( De Sousa, DP; Freitas, RM; Islam, MT; Junior, AL; Machado, KC; Oliveira, GL, 2015) |
| "The number of seizure events, severity of seizures, and seizure duration were then compared between the two treatment groups." | ( Bauquier, SH; Chen, Y; Cook, MJ; Halliday, AJ; Jiang, JL; Lai, A; McLean, KJ; Moulton, S; Sui, Y; Wallace, GG; Yue, Z, 2015) |
| "For nearly 30% of people with epilepsy, seizures are not controlled by current treatments." | ( Brigo, F; Igwe, SC; Storti, M, 2015) |
| "Treatment was judged effective when seizure frequencies fell by ⩾75%." | ( Abe, S; Igarashi, A; Ikeno, M; Nakahara, E; Nakazawa, M; Okumura, A; Shimizu, T; Takasu, M, 2016) |
| "We aimed to analyze the value of seizure reduction and radiological response as prognostic markers of survival in patients with low-grade glioma (LGG) treated with temozolomide (TMZ) chemotherapy." | ( Dirven, L; Heimans, JJ; Koekkoek, JA; Postma, TJ; Reijneveld, JC; Taphoorn, MJ; Vos, MJ, 2016) |
| "Efficacy of the KD (defined as 50% seizure reduction) was evaluated after three months of treatment and related to the AEDs used." | ( Catsman-Berrevoets, CE; Desadien, R; Neuteboom, RF; van der Louw, EJ; van der Sijs, H; Vehmeijer, FO, 2015) |
| "Patients with seizure and abnormal findings on electroencephalography after initial treatments had lower fractional anisotropy and higher radial diffusivity." | ( Ando, N; Azuma, Y; Fukasawa, T; Ishihara, N; Ito, Y; Kawai, H; Kidokoro, H; Kubota, T; Naganawa, S; Natsume, J; Ogawa, C; Sakaguchi, Y; Takeuchi, T; Tsuji, T; Yamamoto, H, 2016) |
| "Recurrent seizures had a significant effect on HRQoL, a subtle effect on cognitive performance, and no effect on psychological symptoms over one year in newly diagnosed or previously untreated adults with partial epilepsy." | ( Heo, K; Kim, MJ; Kim, OJ; Kim, SO; Lee, BI; Lee, HW; Lee, SA; Shin, DJ; Song, HK, 2015) |
| "The primary outcome was recurrent convulsions after completion of MgSO4 therapy." | ( Anjum, S; Garg, N; Goel, N; Mohsin, Z; Sharma, R, 2016) |
| "To report a case of refractory seizures following congenital portosystemic shunt (CPSS) ligation that regained normal neurologic and hepatic function with novel treatment." | ( Giordano, P; Heidenreich, DC; Kirby, BM, 2016) |
| "The proportion of different seizure classes, as well as the number of SRS/day were calculated for the vehicle and treatment period." | ( Ali, I; Amhaoul, H; Bhattacharya, A; Bielen, K; Ceusters, M; Dedeurwaerdere, S; Kumar-Singh, S; Lord, B; Missault, S; Mola, M; Rech, J; Szewczyk, K; Van Eetveldt, A, 2016) |
| "Phenytoin is a common medication for seizure treatment and prophylaxis in the intensive care unit (ICU)." | ( Barletta, JF; Bikin, DS; Buckley, MS; Reeves, BA, 2016) |
| "The threshold for seizure induction with progressive intravenous infusion of pentylenetrazole (PTZ) was evaluated in anesthetized Wistar rats after a ten-day oral administration of BD-AcAc2 (gavage)." | ( Arnold, P; Coppola, G; D'Agostino, D; Monda, M; Pilla, R; Viggiano, A; Zeppa, P, 2016) |
| "Felbamate was approved in 1993 to treat partial seizures with and without secondary generalization in adults and in Lennox-Gastaut Syndrome in children." | ( Devinsky, O; Friedman, D; Kothare, SV; Shah, YD; Singh, K, 2016) |
| "Electroconvulsive seizures (ECS), an animal model of electroconvulsive therapy, strongly stimulate hippocampal neurogenesis, but it is not known how this relates to the therapeutic effect or to the unwanted cognitive side effects." | ( Ekstrand, J; Grahm, M; Höglund, P; Johansson, M; Svensson, M; Tingström, A, 2016) |
| "LEV3D treatment attenuated seizure activity with significant reductions in NCS incidence (54%), frequency, duration, and delayed latency to seizure onset compared to vehicle treatment." | ( Caudle, KL; Lu, XC; Mountney, A; Shear, DA; Tortella, FC, 2016) |
| "Although spontaneous behavioral seizures have been reported previously in this mouse model, the observation of seizures and death consequential to fluoxetine treatment is new." | ( de Nijs, L; Hoogland, G; Prickaerts, J; Rutten, BP; Sierksma, AS; Steinbusch, HW; van den Hove, DL; van Leeuwen, FW; Vanmierlo, T, 2016) |
| "Antitumour therapy can contribute to seizure control, and antiepileptic drugs might have beneficial effects on tumours." | ( Huberfeld, G; Vecht, CJ, 2016) |
| "Pretreatment with LU suppressed seizure induction, duration, and severity following PTZ injection, reversed cognitive impairment, reduced neuronal and oxidative stress damage, and increased phosphoactivation of PKA and CREB as well as BDNF expression." | ( Chang, YN; Fu, T; Liu, JQ; Qu, ZZ; Wang, WP; Zhen, JL, 2016) |
| "Reflex epileptic seizures can often be prevented by avoidance or modification of triggers or by prophylactic benzodiazepine administration." | ( Guaranha, M; Lin, K; Wolf, P, 2016) |
| "The maximum seizure burden evaluated 1 h before each phenobarbitone dose (T-1) was compared to seizure burden in periods of increasing duration after each phenobarbitone dose had been administered (T+1, T+2 to seizure offset)." | ( Boylan, GB; Livingstone, V; Low, E; Mathieson, SR; Rennie, JM; Ryan, AC; Stevenson, NJ, 2016) |
| "Phenobarbitone significantly reduced seizures within 1 h of administration as assessed with continuous multi-channel EEG monitoring in neonates." | ( Boylan, GB; Livingstone, V; Low, E; Mathieson, SR; Rennie, JM; Ryan, AC; Stevenson, NJ, 2016) |
| "However, intermittent seizures were recorded on electroencephalogram from 6 h after diazepam treatment until 24 h, but had disappeared after 15 days." | ( Ardourel, MY; Calas, AG; Herzine, A; Lauga, F; Menuet, A; Montécot-Dubourg, C; Mortaud, S; Palomo, J; Pâris, A; Perche, A; Perche, O; Pichon, J; Richard, O, 2016) |
| "The pivotal trials demonstrated that seizure control following conversion from other AEDs was superior for eslicarbazepine acetate monotherapy (1200 or 1600 mg once daily) compared with a pseudo-placebo historical control." | ( Dhillon, S; Shirley, M, 2016) |
| "Patients with any type of seizure or epilepsy syndrome were recruited in 16 neurological and neuropediatric centers in Germany if the treating physician decided to administer LCM-iv for any reason." | ( Bös, M; Bösel, J; Burghaus, L; Dziewas, R; Evers, S; Kellinghaus, C; Kraft, A; Lammers, T; Lang, N; Lange, M; Ruf, S; Sabolek, M; Schmitt, FC; Schubert-Bast, S; Stephani, U; van Baalen, A; Weber, Y, 2016) |
| "Studies were included if they reported seizure frequency data pertaining to levetiracetam use in patients with brain tumors as either monotherapy or as an add on agent." | ( Nasr, ZG; Paravattil, B; Wilby, KJ, 2016) |
| "Effects on seizure threshold and locomotion were studied using C57BL/6N mice and compared with saline-treated controls." | ( Haider, M; Hering, S; Hintersteiner, J; Khom, S; Luger, D; Mihovilovic, MD; Pototschnig, G; Schwarzer, C, 2016) |
| "SAHA pretreatment increased seizure latency and decreased seizure scores." | ( Hu, QP; Mao, DA, 2016) |
| "The increased frequency of seizures may enable raised awareness of clinicians for potential complications and treatment adjustments perioperatively early at clinical admission." | ( Eicker, SO; Emami, P; Lamszus, K; Matschke, J; Mohme, M; Regelsberger, J; Westphal, M, 2016) |
| "Firstly, seizure latency induced by pentylenetetrazole was significantly prolonged 6 weeks after brain injury in group of SR141716A treatment." | ( Liu, C; Wang, X; Wang, Y; Wei, N; Zhang, C; Zhang, JG; Zhang, K; Zhao, B, 2016) |
| "After treatment, convulsions were suppressed and daily life continued, but intellectual impairment and high-level dysfunction remained." | ( Endo, W; Haginoya, K; Kitamura, T; Nishio, T; Numata, Y; Ohura, T; Takayanagi, M; Uchida, T, 2016) |
| "Chronotherapy tailored to the patients' seizure susceptibility patterns may improve care in epilepsy patients as differential dosing may allow for higher overall treatment doses at times of greatest seizure susceptibility without increased side effects at other times." | ( Fernández, IS; Jackson, M; Kadish, NE; Klehm, J; Loddenkemper, T; Manganaro, S; Thome-Souza, S, 2016) |
| "In the present study soman-induced seizures were also substantially prevented when the animals were intravenously treated with tariquidar post-poisoning, in addition to HI-6 and atropine." | ( Hamelink, J; Joosen, MJA; Klaassen, SD; van den Berg, RM; Vester, SM, 2016) |
| "After treatment, median seizure frequency reduction was 50% overall, 50% in children, and 33% in adults; 44% in primary generalized, 38% in secondarily generalized, and 33% in partial seizures." | ( Devinsky, O; Friedman, D; Kothare, SV; Luciano, D; Shah, YD; Singh, K, 2016) |
| "The effect of 5-HTP administration on seizure-induced mortality evoked by acoustic stimulation or by PTZ was investigated in DBA/1 mice." | ( Cotten, JF; Feng, HJ; Xue, Q; Yang, X; Zhang, H; Zhao, H, 2016) |
| "This toxicity, which manifested as seizures, bradycardia, hypotension, nausea, and emesis, was rapidly recognized and appropriately treated, with a good clinical outcome for the patient." | ( Nicholas, E; Thornton, MD, 2016) |
| "• For seizures with duration of more than 5 min, the administration of anticonvulsive rescue medication is recommended." | ( Bernhard, MK; Bertsche, A; Bertsche, T; Frontini, R; Hoppe, SC; Kaune, A; Kiess, W; Merkenschlager, A; Neininger, MP; Schumacher, PM; Syrbe, S, 2016) |
| "Remission of recurrent, unprovoked seizures can be achieved in two-thirds of cases by treatment with anticonvulsant medication, surgical resection, and/or nerve/brain electrode stimulation." | ( Beyer, BS; Ferland, RJ; Herron, BJ; Kadiyala, SB; Nalwalk, JW; Papandrea, D; Yannix, JQ, 2016) |
| "Here, we suggest that triggering limbic seizures with low doses of PTZ in pilocarpine-treated marmosets might provide a more effective basis for the development of AED." | ( Blanco, MM; Cinini, SM; Lima, TZ; Mello, LE; Pontes, JC; Queiroz, CM, 2016) |
| "The effect of chronic seizures and ASD administration on cognitive performance in NOPR was also determined with corneal-kindled mice." | ( Barker-Haliski, ML; Mau, MJ; Underwood, TK; Vanegas, F; White, HS, 2016) |
| "Understanding the seizure-inducing mechanisms of TBI is of the utmost importance, because these seizures are often resistant to traditional first- and second-line anti-seizure treatments." | ( Cotrina, ML; Gu, S; He, X; Huang, JH; Liu, W; Nedergaard, M; Shapiro, LA; Wang, EW; Wang, F; Wang, W; Wang, X, 2017) |
| "Higher ≥50% and ≥75% responder and seizure freedom rates were observed in lacosamide-treated patients vs placebo." | ( Du, X; Hong, Z; Inoue, Y; Liao, W; Meng, H; Tennigkeit, F; Wang, W; Wang, X; Zhang, L; Zhou, L, 2016) |
| "an acute anti-seizure effect after IV LCM was especially evident when it was first used - (SC) or second line (established SE) treatment." | ( Avolio, C; Carapelle, E; d'Orsi, G; Di Claudio, MT; Mancini, D; Martino, T; Pacillo, F; Pascarella, MG; Specchio, LM; Trivisano, M, 2016) |
| "Improved seizure control was maintained for 4 years in the majority of patients with TSC with medically refractory epilepsy treated with everolimus." | ( Agricola, K; Capal, J; Franz, DN; Holland-Bouley, K; Krueger, DA; Mays, M; Talley, CM; Tudor, C; Wilfong, AA, 2016) |
| "Neonatal seizures are a common problem in the neonatal intensive care unit and are frequently treated with antiepileptic drugs." | ( Ahmad, KA; Ahmad, SF; Bennett, MM; Clark, RH; Desai, SJ; Ng, YT; Tolia, VN, 2017) |
| "After 12 hours of seizure free period of the initial loading dose of phenobarbitone, one group received IV maintenance therapy and other 'no maintenance' (saline as placebo)." | ( Gupta, P; Saxena, P; Sharma, S; Singh, A; Upadhyay, A; Vishnubatla, S, 2016) |
| "Cysticidal therapy leads to better seizure control and increased resolution of lesions on short-term follow-up." | ( Deo, B; Khandelwal, NK; Malhi, P; Singhi, P; Suthar, R, 2017) |
| "Side effects and seizure frequency when phenobarbital was administered every 12 hours or 8 hours were compared." | ( Barnett, CR; De Risio, L; Stabile, F, 2017) |
| "Treatment-related seizures were associated with leukoencephalopathy and decreased neuropsychological performance." | ( Ashford, JM; Cheng, C; Conklin, HM; Glass, JO; Jeha, S; Laningham, FH; Nassar, SL; Pui, CH; Reddick, WE; Zhou, Y, 2017) |
| "In PTZ-induced acute seizures model, behavioral assay showed that chronic metformin treatment decreased the mortality, and LFPs recording showed that chronic metformin treatment shortened the duration of generalized tonic-clonic seizures and prolonged the duration of postictal depression." | ( Hu, Y; Li, Y; Wang, X; Yang, Y; Zhang, Y; Zheng, F; Zhu, B, 2017) |
| "Importantly, GR1 demonstrated anti-seizure properties and reduced post-seizure hyperexcitability in neonatal mice, highlighting its drug candidate potential for treating epilepsies and other neurological diseases involving network hyperexcitability." | ( Coughlin, DJ; Lutz, GJ; Lykens, NM; Reddi, JM; Tallent, MK, 2017) |
| "Obestatin treatment reduced the average seizure score, decreased the occurrence and duration of generalized tonic-clonic seizures, presenting with a shorter latency to their onset." | ( Akakın, D; Atal, SS; Kervancıoğlu Demirci, E; Koyuncuoğlu, T; Üren, D; Vızdıklar, C; Yeğen, BÇ; Yıldırım, Ç; Yılmaz, H; Yüksel, M, 2017) |
| "Understanding how the brain responds to seizures is important for development of new treatment strategies for epilepsy, a neurological condition characterized by recurrent and unprovoked seizures." | ( Beattie, CE; Berberoglu, MA; Duy, PQ; Hall, CW, 2017) |
| "Distinctive seizure-like events (SLEs) are induced in the olfactory regions by acute treatment of both tangential brain slices and the isolated guinea pig brain with the potassium channel blocker 4-aminopyridine." | ( Chikhladze, M; de Curtis, M; Gnatkovsky, V; Milesi, G; Morbin, M; Saccucci, S; Tassi, L; Uva, L, 2017) |
| "156,539 benzodiazepine-treated seizures were identified." | ( Meurer, WJ; Shtull-Leber, E; Silbergleit, R, 2017) |
| "The events leading to seizure generation and epileptogenesis remain largely unknown, hindering development of new treatments." | ( Binder, DK; Fiacco, TA; Murphy, TR, 2017) |
| "Motor seizure frequency, quality of life, and adverse events were recorded from the eighth week of the pretreatment period, eight weeks after starting maintenance dose (week 14), and the most recent visit." | ( Comi, AM; Kaplan, EH; Offermann, EA; Sievers, JW, 2017) |
| "The presence of subclinical seizures, monotherapy treatment failure, and distribution of seizure burden (including status epilepticus) was similar in preterm and term neonates." | ( Abend, NS; Bonifacio, SL; Chang, T; Chu, CJ; Cilio, MR; Glass, HC; Massey, SL; Shellhaas, RA; Soul, JS; Tsuchida, TN; Wusthoff, CJ, 2017) |
| "The present study examined seizure clusters as a primary outcome in patients receiving treatment for PNES." | ( Baird, GL; Harlow, LL; LaFrance, WC; Machan, JT, 2017) |
| "CORM-A1, administered before or during seizures, greatly improved the outcome of seizures on cerebrovascular functions in both male and female piglets." | ( Fedinec, AL; Leffler, CW; Liu, J; Parfenova, H; Pourcyrous, M, 2017) |
| "Decrease of both the frequency of seizures and the incidence of ADRs after TDM implementation suggests that TDM may have given clinicians the opportunity to achieve more optimal patient treatment." | ( Brozmanova, H; Grundmann, M; Kacirova, I; Koristkova, B, 2017) |
| "The search for new treatments for seizures and epilepsy relies upon studies in animal models of epilepsy." | ( Anbazhagan, A; Chen, M; Reutens, DC; Tieng, QM, 2017) |
| "Mean seizure stages or generalized seizure durations in the 10 and 20 mg/kg lamotrigine pretreated groups were significantly lower or shorter when received 3 times of pentylenetetrazole after the washout period." | ( Chen, Y; Fang, Z; He, X; Sun, Q; Zhou, L, 2017) |
| "Repetitive and continuous seizures that do not respond to benzodiazepines require second line therapy." | ( Alunday, RL; Bussmann, S; Lee, T; Sarangarm, P; Seifert, SA; Smolinske, SC; Warrick, BJ, 2018) |
| "Eleven GCSE patients (65%) remained seizure free after LEV therapy." | ( Alunday, RL; Bussmann, S; Lee, T; Sarangarm, P; Seifert, SA; Smolinske, SC; Warrick, BJ, 2018) |
| "Patients developing seizures during their ertapenem treatment course were identified as case patients." | ( Cho, HL; Hsiao, CY; Huang, YJ; Hung, MC; Hung, SC; Lai, LF; Lee, YC; Tong, SH; Wang, JT, 2017) |
| "The development of ertapenem-associated seizures may occur more frequently and much earlier due to its widespread use in treating drug-resistant pathogens, especially when these pathogens emerged worldwide." | ( Cho, HL; Hsiao, CY; Huang, YJ; Hung, MC; Hung, SC; Lai, LF; Lee, YC; Tong, SH; Wang, JT, 2017) |
| "We induced generalized tonic-clonic seizures with the administration of 60 mg/kg pentylenetetrazole (PTZ) in male Wistar Albino rats." | ( Ateş, N; Dede, F; Eraldemir, FC; Karadenizli, S; Özsoy, ÖD; Şahin, D, 2017) |
| "Caffeine pretreatment did not change seizure latency and seizure duration." | ( Ateş, N; Dede, F; Eraldemir, FC; Karadenizli, S; Özsoy, ÖD; Şahin, D, 2017) |
| "The intensity of seizures in pretreated mice varied significantly according to circadian stage." | ( Aouam, K; Ben-Attia, M; Boughattas, NA; Dridi, I; Khedhaier, WBC; Reinberg, A, 2017) |
| "For effective control of seizures, antiepileptic drugs (AEDs) are administered at higher dose which is associated with several adverse effects." | ( Gupta, YK; Joshi, D; Kaleekal, T; Kumar, R; Sarangi, SC, 2017) |
| "Treatment for refractory seizures included benzodiazepines and eventual intubation and sedation with propofol." | ( Ovakim, DH; Powell, JD; Thompson, J, 2018) |
| "Recurrent and prolonged seizures are harmful for the developing brain, emphasizing the importance of early seizure recognition and effective therapy." | ( Brilstra, E; Cilio, MR; de Vries, LS; Mendes Ribeiro, J; Striano, P; Vilan, A; Weckhuysen, S; Weeke, LC, 2017) |
| "Semiology, seizure frequency, and therapy were assessed for all patients." | ( Bisulli, F; Ferri, L; Gramegna, LL; Licchetta, L; Lodi, R; Naldi, I; Rizzo, G; Testa, C; Tinuper, P; Tonon, C, 2017) |
| "Tonic seizures with high-voltage discharges over the contralateral cerebral hemisphere and secondary generalization were successfully treated with phenobarbital." | ( Bohner, G; Bührer, C; Dame, C; Mühlbacher, T, 2018) |
| "The onset and frequency of the convulsions, as well as fatality, were dependent on the amount of Urografin® administered." | ( Ezaki, J; Kibayashi, K; Shimada, R, 2017) |
| "Pretreatment with genistein delayed seizure onset, reduced the seizure duration, improved oxidative stress profile, decreased estrogen receptor expression, reduced apoptosis, and improved the histopathological pattern." | ( Elsayed, AA; Ibrahim, BMM; Khalifa, AE; Menze, ET; Sabri, NA; Tadros, MG, 2018) |
| "A 77-year-old man developed a seizure after administration of enzalutamide." | ( Iwanishi, T; Kobayashi, M; Koida, Y; Komori, K; Ono, Y; Yumiba, S, 2017) |
| "We assessed the seizure vulnerability and anxiety responses following the chronic co-administration of, and withdrawal from, caffeine and ethanol in male rats." | ( Alele, PE; Matovu, D, 2018) |
| "A neonate with prolonged seizures was administered PB." | ( Graudins, A; Johnstone, LM; Le Page, AK; Roehr, CC; Stewart, AE, 2018) |
| "In the strychnine-induced seizure test, PSE treatment did not significantly affect the latency to convulsions and time until death when compared to controls." | ( Abotsi, WKM; Boakye-Gyasi, E; Daanaa, S; Woode, E, 2018) |
| "The cat remained seizure free with no recurrence of the aforementioned concerns after reinstitution of phenobarbital treatment." | ( Collinet, A; Sammut, V, 2017) |
| "Epileptic seizures are refractory to treatment in approximately one-third of patients despite the recent introduction of many newer antiepileptic drugs (AEDs)." | ( Dash, A; Desudchit, T; Leung, H; Lim, KS; Tiamkao, S; Tsai, JJ; Wu, T, 2018) |
| "Neonatal seizures are treated with phenobarbital and prolonged treatment does not prevent postneonatal epilepsy." | ( Beatty, CW; Gust, J; Hamiwka, L; Natarajan, N, 2018) |
| "She was treated with CsA and developed seizures, progressive loss of consciousness, and visual disturbance on the 7th day of treatment." | ( Gavrilovici, C; Miron, I; Munteanu, M; Stârcea, M, 2018) |
| "Despite the development of newer anti-seizure medications over the past 50 years, 30-40% of patients with epilepsy remain refractory to treatment." | ( de la Hoz, CL; Gavrilovici, C; Ibhazehiebo, K; Kaushik, G; Kim, DY; Kurrasch, DM; Ma, SC; Meza Santoscoy, PL; Nath, N; Rehak, R; Rho, JM; Scott, L, 2018) |
| "Caffeine can increase seizure susceptibility and protect from seizures, depending on the dose, administration type (chronic or acute), and the developmental stage at which caffeine exposure started." | ( Bauer, PR; Sander, JW; Schuitema, I; van Koert, RR; Visser, GH, 2018) |
| "Seven days postseizure, saline-treated animals were found to have reduced left ventricular function, increased fibrotic scarring, and an elevated risk of aconitine-induced arrhythmias." | ( Harrison, JC; Kerr, DS; McCann, DM; Millen, RN; Read, MI; Sammut, IA, 2018) |
| "Attenuation of seizure with diazepam offered no cardiac protection; however, coadministration of atenolol with diazepam prevented the development of seizure-induced cardiac dysfunction." | ( Harrison, JC; Kerr, DS; McCann, DM; Millen, RN; Read, MI; Sammut, IA, 2018) |
| "Some patients reported less vigorous seizures, shorter duration of seizures, shorter time to recovery, and other positive side effects of CBD treatment." | ( Neubauer, D; Osredkar, D; Perković Benedik, M, 2018) |
| "excellent seizure outcome group and not-excellent seizure outcome group after methylprednisolone treatment." | ( Bian, KG; Gong, P; Liu, XY; Qian, P; Xue, J; Yang, HP; Yang, ZX, 2018) |
| "Mean seizure frequency was compared between the 3-month baseline period and subsequent 3-month treatment period." | ( Andres, E; Hamer, H; Kerling, F; Winterholler, M, 2018) |
| "A total of 174 children with generalized seizures on VPA therapy were enrolled." | ( Fang, F; Feng, W; Gao, B; Mei, S; Wu, X; Yang, W; Yu, Y; Zhao, Z; Zhu, L, 2018) |
| "In children with generalized seizures on VPA therapy, polymorphisms of UGT2B7, CYP3A4, and SCN1A genes were associated with seizure reduction." | ( Fang, F; Feng, W; Gao, B; Mei, S; Wu, X; Yang, W; Yu, Y; Zhao, Z; Zhu, L, 2018) |
| "Clinical response (number of seizures per week) was evaluated on third and sixth month of the therapy." | ( Ali, N; Nazish, H; Shakir, S, 2018) |
| "FR180204 had no significant effect on seizure parameters when administered at the dose of 1 μg/μl in kindled group of animals." | ( Dehghan, S; Komaki, A; Mardani, P; Mirnajafi-Zadeh, J; Oryan, S; Sarihi, A; Shojaei, A, 2018) |
| "For nearly 30% of people with epilepsy, seizures are not controlled by current treatments." | ( Bragazzi, NL; Brigo, F; Igwe, SC, 2018) |
| "Serotonin syndrome and seizures can be effectively treated by administering benzodiazepines, providing supportive care, and discontinuing tramadol and other contributing agents." | ( Dale, W; Danovitch, I; Hassamal, S; Miotto, K, 2018) |
| "To assess seizure activity, we employed 2 in vivo mouse models of epilepsy, intravenous (iv) pentylenetetrazol (PTZ) and hippocampal electrical kindling, in the presence or absence of Sema4D treatment." | ( Acker, DWM; Kang, M; Paradis, S; Wong, I, 2018) |
| "midazolam as first-line treatment for seizures." | ( Dao, K; Diezi, M; Giannoni, E; Lebon, S; Roulet-Perez, E, 2018) |
| "There were a total of 38 seizures in 33 patients when all treatment pressures were examined." | ( Sherlock, S; Tabah, A; Way, M, 2018) |
| "Of the patients, total number of seizures and seizure control rates 6 months before and 3 and 6 months after the add-on treatment were compared." | ( Acar, T; Aras, YG, 2018) |
| "TTA-P2 (10 mg/kg) reduced seizure severity in mice undergoing alcohol WD with concurrent PTZ treatment (20 mg/kg)." | ( Godwin, DW; Masicampo, ML; Shan, HQ; Speagle, M; Xu, V, 2018) |
| "To predict the probability of a seizure-free (SF) state in patients with epilepsy (PWEs) after treatment with levetiracetam and to identify the clinical and electroencephalographic (EEG) factors that affect outcomes." | ( Han, JY; Han, X; He, GN; Huang, DL; Wang, N; Zhang, JH; Zhang, Y; Zhao, D; Zhao, HW; Zhao, T; Zhu, XR, 2018) |
| "Flurothyl-induced seizures (RS group) produced long-term abnormal neurobehavior, which was improved with leptin treatment." | ( Jin, MF; Li, LL; Li, YC; Ni, H; Zhao, DJ, 2018) |
| "Organophosphate (OP) induced seizures are commonly treated with anticholinergics, oximes and anticonvulsants." | ( Cornelissen, AS; Hesseling, P; Joosen, MJA; Klaassen, SD; Lucassen, PJ; Meerhoff, GF; Vester, SM, 2018) |
| "Responder rate (≥50% seizure frequency reduction) and seizure freedom rate (seizure freedom at least since prior visit) were assessed after 3, 6 and 12 months of ESL treatment and at last visit." | ( Delanty, N; Holtkamp, M; McMurray, R; Sales, F; Serratosa, J; Villanueva, V, 2019) |
| "When tested 3-4 days after five stage-5 seizures, 10 mg/kg naloxone-treated rats, as compared to saline-treated rats, showed a statistically significant loss of gating of hippocampal auditory evoked potentials, and significant reduction of startle response amplitude, but non-significant differences in prepulse inhibition and methamphetamine-induced locomotion." | ( Leung, LS; Ma, J, 2019) |
| "BACKGROUND Recurrent seizure in patients with magnesium sulfate-treated eclampsia is very rare and requires meticulous management due to poor prognosis." | ( Achmadi, A; Aldika Akbar, MI; Harsono, AAH; Joewono, HT, 2018) |
| "Side-effects such as hypersensitivity, convulsion and arrhythmia were also recorded in the patients and infants in group A within 24 h after aminophylline administration." | ( Chen, T; Ni, X; Wang, W; Yang, CJ; Yu, WY, 2019) |
| "Patient selection for seizure prophylaxis after traumatic brain injury (TBI) and duration of anti-epileptic drug treatment for patients with early post-traumatic seizures (PTS), remain plagued with uncertainty." | ( Anwar, F; Belli, A; Bulters, D; Chari, A; Coles, J; Duncan, JS; Ercole, A; Ham, T; Hutchinson, PJ; Kolias, AG; Lecky, F; Manford, M; Marson, AG; McMahon, C; Mee, H; Tudur-Smith, C; Turner, C; Uff, C; Wilson, MH, 2019) |
| "These data suggest that convulsive seizures can be obtained in FPI-treated rats when NSS is used as an inclusion criterion to select rats with severe injury." | ( Kelly, W; MacWilliams, Z; Patterson, D; Poulsen, A; Poulsen, D; Rau, T; Smith, D, 2018) |
| "After identification of seizures, infants were treated with PHB or LEV at the discretion of treating physicians." | ( Chanlaw, T; Cho, A; Garg, M; Hussain, SA; Rao, LM; Sankar, R; Zaki, T, 2018) |
| "Our lab has demonstrated that TBI or seizure-induced oxidative injury and neuronal death were reduced by apocynin treatment." | ( Choi, BY; Choi, HC; Hong, DK; Jeong, JH; Kang, BS; Kang, DH; Kho, AR; Lee, SH; Song, HK; Suh, SW, 2018) |
| "An increased frequency of seizures was observed in three cases after the second year of treatment." | ( Canpolat, M; Coskun, A; Gumus, H; Kumandas, S; Per, H, 2018) |
| "He had a history of neonatal seizures, had been stabilized with vigabatrin, and was seizure free without treatment for several months." | ( Amad, A; Corfiotti, C; Ferrafiat, V; Jardri, R; Leroy, A; Medjkane, F; Nguyen The Tich, S, 2018) |
| "The results showed reduction in the seizure score, percentage of kindled rats and neurological damage score in DMF treated rats." | ( Banerjee, D; Bhatia, A; Chakrabarti, A; Kumari, P; Saha, L; Singh, J; Singh, N, 2019) |
| "The 6-Hz psychomotor seizure induced ultra-structural changes in both cortex and hippocampus in mice treated with PCPA." | ( Jahan, K; Pillai, KK; Vohora, D, 2019) |
| "Eighty-nine children with focal seizures on VPA therapy were enrolled." | ( Fang, F; Feng, W; Gao, B; Han, J; Li, J; Mei, S; Wu, Y; Yu, Y; Zhao, Z; Zhu, L, 2019) |
| "We evaluated the acute antiseizure effect of CBD in the maximal electroshock seizure, 6-Hz psychomotor seizure, and pentylenetetrazol acute seizure tests, as well as the corneal kindling model of chronic seizures in mice following intraperitoneal administration." | ( Barker-Haliski, M; Bazelot, M; Glyn, S; Jones, N; McNeish, AJ; Patra, PH; Sandhu, H; Whalley, BJ; White, HS; Williams, CM, 2019) |
| "CBD was effective in a battery of acute seizure models in both mice and rats following intraperitoneal administration." | ( Barker-Haliski, M; Bazelot, M; Glyn, S; Jones, N; McNeish, AJ; Patra, PH; Sandhu, H; Whalley, BJ; White, HS; Williams, CM, 2019) |
| "Epileptic seizures are frequent in patients with glioblastoma, and anticonvulsive treatment is often necessary." | ( Bergner, C; Hörnschemeyer, J; Kirschstein, T; Köhling, R; Krause, BJ; Lange, F; Linnebacher, M; Mullins, CS; Porath, K; Weßlau, K, 2019) |
| "The treatment of choice for CAE with absence seizures only is ethosuximide." | ( Kessler, SK; McGinnis, E, 2019) |
| "The EEG-recorded seizure activity was also evaluated in two treatment protocols." | ( Atanasova, D; Galchev, T; Kortenska, L; Lazarov, N; Marinov, P; Shishmanova-Doseva, M; Tchekalarova, J, 2019) |
| "Treatment of seizures in the neonatal patient is urgent and time sensitive." | ( Anderson, J; Arboleda, N; Calleo, V, 2018) |
| "After an episode of clonic seizures on day 11, phenobarbitone was administered intravenously at a loading dose of 20 mg/kg followed by maintenance doses of 6 mg/kg per day in 2 divided doses for 5 days." | ( Dudeja, S; Dutta, S; Krishnamurthy, B; Pattanaik, S, 2019) |
| "Epilepsy is marked by seizures that are a manifestation of excessive brain activity and is symptomatically treatable by anti-epileptic drugs (AEDs)." | ( Choo, BKM; Johan Arief, MFB; Kumari, Y; Kundap, UP; Othman, I; Shaikh, MF; Wong, CP; Yap, JL, 2019) |
| "DFP triggered rapid and sustained seizure behavior irrespective of PB pretreatment, and there was no significant difference in average seizure behavior score during the first 4 h following injection between DFP animals pretreated with PB or not." | ( Bruun, DA; Guignet, M; Harvey, DJ; Lein, PJ, 2019) |
| "He had seizures since the newborn period and he had been treated with phenobarbital but there was no favorable response to therapy." | ( Alan, B; Ceylaner, S; Kasapkara, CS; Kurt, ANÇ; Nergız, ME; Özlü, SG; Yılmaz, S, 2019) |
| "In this study, mice in which epileptic seizures were induced by administering picrotoxin (PTX) were used as a case group, and mice injected with saline were employed as the control group." | ( He, Z; Li, D; Li, P; Li, Y; Liang, L; Luo, X; Ma, J; Qin, L; Sun, Y; Zhou, X, 2019) |
| "Five patients who had seizures after administration of normal saline were administered 10 mg/kg of PB, and no patients had a seizure thereafter." | ( Nakagawa, T; Takami, Y, 2019) |
| "Thereafter, PTZ seizure threshold was measured in control and treated rats, and different brain regions were analyzed for levels of oxidative stress biomarkers." | ( Al Yacoub, ON; Alomari, MA; Alrabadi, NN; Alzoubi, KH; Banihani, SA; Hasan, ZA; Khabour, OF; Mayyas, FA, 2019) |
| "against strychnine induced convulsions model, at 1, 7, 15 and 30th day of treatment." | ( Fatima, A; Maqbool, S; Sadaf, R; Younus, I, 2019) |
| "Rats with KA-induced seizures showed longer average escape latency and decreases in the number of platform crossings and average time spent in the target quadrant in the Morris water maze; ISL pretreatment reversed this decline in cognitive impairment and increased the protein levels of synaptophysin, postsynaptic density-95 and brain-derived neurotrophic factor while reducing the number of Fluoro Jade B-positive cells, microglia, and astrocytes; cleaved-Caspase-3 and -9 protein levels; and tumor necrosis factor-α, interleukin (IL)-1β, and IL-18 production." | ( Chen, O; Huang, S; Liu, J; Wang, Y; Xue, J; Zhu, W; Zhu, X, 2019) |
| "Furthermore, KN-93 is able to attenuate seizure behaviors by preventing its effects on neuron loss, so, it is valuable for the treatment of epileptic seizures." | ( Ebrahimi, F; Khamse, S; Mohammadian Haftcheshmeh, S; Mohseni-Moghaddam, P; Navid Hamidi, M; Roghani, M; Sadr, SS; Zamani, E, 2019) |
| "Unlike the seizure induced by PTZ, or pilocarpine, induction of seizure by PTZ + pilocarpine was resistant to phenytoin and sodium valproate treatment." | ( Jand, A; Mousavi-Hasanzadeh, M; Palizvan, MR; Rezaeian-Varmaziar, H; Shafaat, O, 2019) |
| "Neonatal seizures are different from adult seizures, and many antiepileptic drugs that are effective in adults often fail to treat neonates." | ( Bai, Y; Chen, G; Dong, F; Feng, M; Huo, Q; Li, ST; Long, C; Lüscher, B; Ren, L; Wang, GL; Wang, Y; Wu, G; Wu, Z, 2019) |
| "Rapid control of seizure activity is important to minimize neuronal injury and the resulting neurological and behavioral disorders; however, early treatment will not be possible after mass release of OPs or NAs." | ( Bealer, SL; Dudek, FE; Pouliot, W; Roach, B; Spampanato, J, 2019) |
| "MDZ-induced seizure suppression was equivalent in magnitude regardless of treatment delay (ie, seizure duration)." | ( Bealer, SL; Dudek, FE; Pouliot, W; Roach, B; Spampanato, J, 2019) |
| "The patient has remained seizure-free for 23 months and demonstrated an excellent response to pulsed dye laser treatment." | ( López-Gutiérrez, JC; Sánchez-Carpintero, I; Triana Junco, PE, 2019) |
| "We found reduced seizure worries over time among people with epilepsy allocated to either generic switch or continued treatment with brand LEV." | ( Källén, K; Olsson, P; Reimers, A, 2019) |
| "Patients with focal seizures taking ESL monotherapy had excellent retention, high seizure-free rates, and good tolerability up to 2 years." | ( Alvarez, BM; Baiges, JJ; Bermejo, P; Bertol, V; Bonet, M; Castro-Vilanova, MD; Esteve, P; Galiano, ML; Garcés, M; Giner, P; Hampel, K; López-González, FJ; Massot-Tarrús, A; Mauri, JÁ; Montoya, J; Ojeda, J; Poza, JJ; Quiroga-Subirana, P; Rodríguez-Osorio, X; Rodriguez-Uranga, JJ; Ruiz-Giménez, J; Toledo, M; Tortosa-Conesa, D; Villanueva, V, 2019) |
| "KA-induced seizure score and elevations of glutamate release in rat hippocampi were inhibited by pretreatment with dexmedetomidine." | ( Chiu, KM; Lee, MY; Lin, TY; Lu, CW; Wang, MJ; Wang, SJ, 2019) |
| "A higher incidence of convulsions and loss of the righting reflex, and decreased rates of survival, as well as elevated CYP2E1 activity, were observed in diabetic rats treated with AN when compared to those in non-diabetic rats, suggesting that diabetes confers susceptibility to the acute toxicity of AN." | ( Dong, Y; Jiang, Y; Li, F; Lu, R; Wang, S; Xing, G; Yang, B, 2021) |
| "Thirty term neonates with seizures were randomized to receive PB or LEV; the Hammersmith Neonatal Neurological Examination (HNNE) was used at baseline (T0) and again one month after the initial treatment (T1)." | ( Barbagallo, M; Corsello, G; Falsaperla, R; Mauceri, L; Pavone, P; Pisani, F; Ruggieri, M; Vitaliti, G, 2019) |
| "The intractable seizures showed complete but transient responsiveness to pyridoxal phosphate and finally controlled by valproate treatment." | ( Chu, VL; Fung, CW; Kwong, AK; Rodenburg, RJT; Smeitink, J, 2019) |
| "On day 15 of injury, seizures were induced by administration of a GABAA receptor antagonist, pentylenetetrazole (PTZ, 30 mg/kg)." | ( Ghadiri, T; Hajali, V; Khodagholi, F; Vakilzadeh, G, 2019) |
| "The effect of treatments on seizure severity was recorded using Racine scale." | ( Adeyemi, OO; Afolayan, OO; Ajayi, AM; Ben-Azu, B; Ishola, IO; James, AB; Ojo, ES; Umukoro, S, 2019) |
| "To evaluate safety- and seizure-related outcomes with repeated intermittent use of a novel formulation of midazolam administered as a single-dose nasal spray (MDZ-NS) in the outpatient treatment of patients experiencing seizure clusters (SCs)." | ( Detyniecki, K; Meng, TC; Pullman, WE; Sequeira, DJ; Van Ess, PJ; Wheless, JW, 2019) |
| "The association between seizure outcomes and treatment over time demonstrated lack of linearity and heterogeneity, requiring the inclusion of time-treatment interaction terms for valid modeling." | ( Carpio, A; Chang, M; Hauser, WA; Jaramillo, A; Kelvin, EA; Romo, ML; Zhang, H, 2019) |
| "RSE was defined as seizure continuing after the first- and second-line treatments." | ( Choi, JY; Hong, JM; Huh, K; Kim, BG; Kim, TJ, 2019) |
| "Early recognition and treatment of seizures is essential for optimal patient outcomes." | ( Abramson, TM; Kearl, YL; Loza-Gomez, A; Rose, E, 2019) |
| "Due to refractory tonic seizures with a frequency of 1 to 4 per day, we initiated cannabidiol (CBD) treatment, raising it to a daily dose of 200 mg." | ( Bast, T; Stiller, B; Wiemer-Kruel, A, 2019) |
| "LEV monotherapy stopped seizures in only a small portion of cases." | ( Courchia, B; Del-Moral, T; Kurtom, W; Pensirikul, A; Sosenko, I, 2019) |
| "Furthermore, PTZ evoked seizure severity was considerably decreased, while latency to clonic-like seizure was increased in adult zebrafish group treated with 100 nM of LY294002." | ( Kumari, S; Mazumder, AG; Singh, D, 2019) |
| "When spontaneous seizures were recorded by continuous (24/7) video-EEG recording starting 6 weeks after termination of treatment, no effects on incidence or frequency of seizures were observed." | ( Anjum, M; Brandt, C; Gericke, B; Hillmann, P; Kaczmarek, E; Löscher, W; Schidlitzki, A; Theilmann, W; Twele, F; Welzel, L, 2020) |
| "Lidocaine is used to treat neonatal seizures refractory to other anticonvulsants." | ( de Haan, TR; Egberts, TCG; Favié, LMA; Groenendaal, F; Huitema, ADR; Nuytemans, DHGM; Rademaker, CMA; Rijken, M; Simons, SHP; van den Broek, MPH; van Straaten, HLM, 2020) |
| "Though atonic seizures were observed during the treatment, it disappeared after isoniazid discontinuation and pyridoxal phosphate administration." | ( Hatoya, S; Hirai, K; Kanegi, R; Nabetani, T; Sugiura, K; Tanaka, T; Wada, Y; Yasugi, M, 2019) |
| "Thus, CXCR7 may regulate epileptic seizures and represents a novel target for antiepileptic treatments." | ( Chen, Y; Deng, J; Liu, X; Liu, Y; Ou, S; Tan, C; Wang, T; Xu, T; Yang, J; Yu, X; Yuan, J, 2019) |
| "In adults with focal seizures, adjunctive BRV treatment does not affect plasma concentrations of the evaluated AEDs but increases carbamazepine epoxide metabolite." | ( Moseley, BD; Otoul, C; Staelens, L; Stockis, A, 2019) |
| "Overall, a uniquely different seizure response profile was detected in the C57BL/6J strain with few observable instances of seizure response despite repeated convulsant administration by two mechanisms." | ( Adhikari, A; Copping, NA; Petkova, SP; Silverman, JL, 2019) |
| "Epileptic seizures are frequent in patients with glioma, and anticonvulsive treatment is often indicated." | ( Kirschstein, T; Köhling, R; Krause, BJ; Lange, F; Mayer, J; Porath, K; Resch, T, 2020) |
| "Audiogenic seizure-prone mice can be protected from seizure-associated death by exposure to an oxygen atmosphere or treatment with selective serotonergic reuptake inhibitors (SSRIs)." | ( Banerjee, A; Gurevich, R; Kollmar, R; Mooney, S; Silverman, JB; Stewart, M; Sundaram, K; Tromblee, J, 2020) |
| "Controlling seizures is essential during GBM treatment because they are often present and closely associated with the quality of life of GBM patients." | ( Chang, MJ; Min, KL; Ryu, JY, 2019) |
| "We examined 122 voluntary reports of seizures (n = 114) and neurological symptoms (syncope, n = 7; and tremor, n = 1) in 123 ENDS users (one report contained information on two users) received by the Food and Drug Administration between December 1, 2010, and June 30, 2019." | ( Faulcon, LM; Limpert, J; Murphy, I; Rudy, S; Wang, B, 2020) |
| "Incidence of olanzapine-induced seizures (OIS) is low with monotherapy." | ( Chachar, AS; Mansoor, M; Mesiya, MH, 2019) |
| "Mean reduction in weekly seizure frequency was greater at the best point of seizure control within the first year than at two months of treatment with CBD, regardless of concomitant CLB usage (all p > 0." | ( Anagnos, CJ; Bruno, PL; Savage, TE; Skirvin, LA; Sourbron, J; Thiele, EA; Wolper, ES, 2020) |
| "We found no significant differences in seizure frequency, duration, severity, or administered KA doses before SE between the groups." | ( Bayat, A; Jones, A; Joshi, S; Koubeissi, MZ; Xiao, X, 2020) |
| "For focal MRE, seizures originate in the epileptogenic zone (EZ), which is the minimum amount of cortex that must be treated to be seizure free." | ( Bulacio, J; Costacurta, J; Fitzgerald, Z; Hu, K; Li, A; Martinez-Gonzalez, J; Palepu, A; Sarma, SV, 2019) |
| "Neonatal seizures are difficult to diagnose and, when they are, tradition dictates first line treatment is phenobarbital." | ( Alix, JJP; Gossling, L; Hart, AR; Stavroulakis, T, 2020) |
| "EPO pretreatment decreased seizure severity and prolonged seizure latency." | ( Akgün-Dar, K; Kaptan, Z; Kapucu, A; Üzüm, G, 2020) |
| "Eliminating or reducing seizures is a main goal of epilepsy treatment, and clinicians rely mainly on patient self-report regarding seizure frequency." | ( Chen, H; Koubeissi, M, 2020) |
| "VGB was administered for 3 and 7 days." | ( Czuczwar, SJ; Krzyżanowski, M; Świąder, K; Świąder, MJ; Wróbel, A; Zakrocka, I; Łuszczki, JJ, 2020) |
| "NMDA-induced seizures consisted of wild running-like behavior (WRLB), flexion seizures (FSs), clonic seizures (CSs), GTCSs, and tonic seizures (TSs); these seizures were observed in both control-treated and PAE-treated, male and female, P7 and P15 rats." | ( Cho, SJ; Khandai, P; Li, T; Lovinger, DM; Luta, G; N'Gouemo, P; Newton, J, 2020) |
| "We examined whether post-seizure anti-inflammatory treatment with dexamethasone after early-life seizures could decrease future seizure susceptibility and ameliorate heightened microglia activation and cell injury in response to later-life seizures." | ( Fox, P; Koh, S; Mithal, DS; Sanchez, RM; Somogyi, JR; Vien, AC, 2020) |
| "Other patients benefit from seizure control by drug therapy at the expense of dose-related toxicity and side effects." | ( Alam, O; Nazar, S; Siddiqui, N, 2020) |
| "Cessation of seizure occurred in 61% of the intramuscular and 46% of the buccal treatment groups, (P = 0." | ( Al Jawala, SA; Alansari, K; Barkat, M; Mohamed, AH; Othman, SA, 2020) |
| "Secondary outcomes included seizure freedom and rescue medication use within 12 h of trial medication administration." | ( Greve, B; Moseley, BD; Sadek, A; Szaflarski, JP; Varner, JA; Williams, P, 2020) |
| "Eleven of 45 patients had a seizure within 12 h of trial medication administration (LZP 5/15 [median time to next seizure: 5." | ( Greve, B; Moseley, BD; Sadek, A; Szaflarski, JP; Varner, JA; Williams, P, 2020) |
| "Appropriate treatment of neonatal seizures with an effective therapy is important in reducing long-term neurologic disabilities." | ( Akisu, M; Aktan, G; Altun Köroğlu, Ö; Dokurel Cetin, İ; Gokben, S; Kanmaz, S; Kultursay, N; Serin, HM; Simsek, E; Tekgul, H; Terek, D; Yalaz, M; Yilmaz, S, 2021) |
| "The overall incidence of seizure during methylphenidate treatment was 4·4 per 10 000 patient-years." | ( Besag, FMC; Coghill, D; Cross, JH; Ip, P; Lau, WCY; Man, KKC; Wong, ICK, 2020) |
| "The incidence of seizures was higher in the period immediately after the start of methylphenidate treatment than in the non-exposed period." | ( Besag, FMC; Coghill, D; Cross, JH; Ip, P; Lau, WCY; Man, KKC; Wong, ICK, 2020) |
| "For nearly 30% of people with epilepsy, seizures are not controlled by current treatments." | ( Bragazzi, NL; Brigo, F; Igwe, SC, 2020) |
| "Despite appropriate antiseizure drug (ASD) treatment, around two-thirds of dogs with idiopathic epilepsy (IE) have seizures long-term and 20-30per cent of affected dogs remain poorly controlled." | ( Añor, S; Conboy, L; de la Fuente, C; Ferreira, A; Gandini, G; Jean-Philippe, C; Luchsinger, E; Menchetti, M; Molina, J; Montoliu, P; Ribeiro, JC; Spycher, A; Varejão, A; Volk, HA; Wenger-Riggenbach, B; Wrzosek, MA; Zanghi, B, 2020) |
| "Exposure, seizure outcomes, and treatment-emergent adverse events (TEAEs) were analyzed." | ( Inoue, Y; Kaneko, S; Krauss, GL; Laurenza, A; Malhotra, M; Patten, A; Rektor, I; Wechsler, RT; Williams, B, 2020) |
| "In the chronic model of seizure, 30 min after the treatment with gamma-decanolactone, mice received pentylenetetrazole once every third day." | ( Fontenla, JA; Gonçalves, DA; Krebs, C; Luft, JG; Pereira, P; Pflüger, P; Regner, GG, 2020) |
| "The few in-ED seizures occurred before medication administration." | ( Barbic, D; Chiu, I; Duley, S; Grafstein, E; Grunau, B; Innes, G; Kestler, A; Lane, DJ; Miles, I; Moe, J; Nolan, S; Scheuermeyer, FX; Slaunwhite, A; Sljivic, I; Ti, L; Yan, A, 2020) |
| "The diagnosis was delayed, coma and convulsions were severe manifestations continuous renal replacement therapy (CRRT) was effective in the treatment of severe cases, and all 6 cases were cured." | ( Chen, W; Chen, ZJ; Fan, XK; Xiang, TX; Yang, LL; Zhong, BT, 2020) |
| "A dose-dependent biphasic seizure modulation of morphine was demonstrated in the acute treatment with morphine; acute treatment at a dose of 0." | ( Aghaei, I; Bahremand, T; Dehpour, AR; Ejtemaei-Mehr, S; Rahimi, N; Shafaroodi, H; Shayan, M; Zamanian, G, 2020) |
| "Automatic seizure detection technology not only reduces workloads of neurologists for epilepsy diagnosis but also is of great significance for treatments of epileptic patients." | ( Hu, X; Leng, Y; Xu, F; Yuan, K; Yuan, Q; Yuan, S, 2020) |
| "All dogs experienced seizure activity in the initial 24 h following extubation and were treated with various anticonvulsant protocols; no patients experienced documented seizures after 48 h of discontinuation from MV." | ( Cortellini, S; Donaldson, RE; Humm, K, 2020) |
| "The relationships between seizure severity change and patient characteristics, changes in seizure frequency, and health-related quality of life (HRQoL) may be important for determining the overall impact of medication therapy on patients with epilepsy." | ( Anastassopoulos, KP; Colman, S; Cramer, JA; Grinnell, T; Mehta, D; Williams, GR, 2020) |
| "Inaccurate subjective seizure counting poses treatment and diagnostic challenges and thus suboptimal quality in epilepsy management." | ( Baud, M; Cook, M; Duun-Henriksen, J; Friedman, D; Heasman, JM; Kjaer, TW; Kouvas, G; Peltola, J; Richardson, MP; Zibrandtsen, IC, 2020) |
| "Phenytoin was administered, and seizures disappeared." | ( Hanaoka, R; Taniguchi, Y, 2021) |
| "Eliciting a generalized seizure is essential to electroconvulsive therapy (ECT), but there is still a need to understand how patient and session variables interact to generate a seizure of adequate quality." | ( Chiavaro da Fonseca, R; Magalhães, PVS; Martini, M; Patusco, LM; Tedeschi, EA; Zahler, S, 2021) |
| "This study examined childhood seizure treatment in a rural area in Japan." | ( Ando, H; Kido, S; Kidokoro, H; Natsume, J; Shiraki, A; Takahashi, Y; Yasui, M, 2021) |
| "We considered etiology, seizure duration, and treatment according to the specialties of the doctors providing initial care." | ( Ando, H; Kido, S; Kidokoro, H; Natsume, J; Shiraki, A; Takahashi, Y; Yasui, M, 2021) |
| "We extracted 236 seizure events: 40 initially treated by pediatricians, 16 by a mobile doctor team, and 180 by other doctors." | ( Ando, H; Kido, S; Kidokoro, H; Natsume, J; Shiraki, A; Takahashi, Y; Yasui, M, 2021) |
| "In rural Japan, many children with seizures are initially treated by doctors other than pediatricians or emergency physicians, and they require a longer time to achieve seizure cessation." | ( Ando, H; Kido, S; Kidokoro, H; Natsume, J; Shiraki, A; Takahashi, Y; Yasui, M, 2021) |
| "On a follow-up visit, six months later, seizure control and tolerance to the chosen treatment were recorded." | ( Baraldés-Rovira, M; Gallego, Y; Mauri-Capdevila, G; Purroy, F; Quílez, A; Sanahuja, J, 2020) |
| "Because theophylline-associated seizures are a major concern, we suggest an evaluation of low-dose theophylline for treating patients with severe pallid breath-holding spells without febrile convulsions or epilepsy before proceeding with permanent pacemaker insertion." | ( Asakai, H; Oda, Y; Sato, A, 2021) |
| "The distinction between acute convulsive seizure and status epilepticus can be misconstrued resulting in BZD administration prior to a patient meeting criteria of status epilepticus." | ( Gopal, M; Greene-Chandos, D; Hamed, M; Hussein, O; Kamdar, HA; Peters, E; Sawalha, K; Shanmugam, K; Smetana, KS; Thakur, G; Yasin, R, 2020) |
| "25 patients had TXA-related seizures postoperatively and were started on anticonvulsant therapy, giving an incidence of 2." | ( Barrow, L; Jenkins, D; Ng, CY; Tan, Z; Valchanov, K, 2020) |
| "Time of follow-up, seizure frequency during early treatment, compliance, annual cost for epilepsy treatment and annual income were related to the seizure outcome." | ( Chen, D; Deng, Y; He, J; He, YJ; Liu, L; Zhou, D; Zhu, LN, 2020) |
| "In addition to these epileptiform seizure-like events, DFP-exposed larvae showed increased neuronal apoptosis, which were both partially alleviated by diazepam treatment, suggesting a causal link between neuronal hyperexcitation and cell death." | ( Bar, O; Brenet, A; Dal-Bo, G; Dupuis, N; Hassan-Abdi, R; Igert, A; Nachon, F; Romain, C; Saurat, D; Somkhit, J; Soussi-Yanicostas, N; Taudon, N; Yanicostas, C, 2020) |
| "The time to the first clinical seizure was significantly longer with preventive than conventional treatment [RCT: 364 days (95% confidence interval [CI] = 223-535) vs 124 days (95% CI = 33-149); OLT: 426 days (95% CI = 258-628) vs 106 days (95% CI = 11-149)]." | ( Aronica, E; Benova, B; Borkowska, J; Curatolo, P; de Ridder, J; Domańska-Pakieła, D; Feucht, M; Głowacka-Walas, J; Hertzberg, C; Hulshof, H; Jansen, AC; Jansen, F; Jóźwiak, S; Kotulska, K; Krsek, P; Kwiatkowski, DJ; Lagae, L; Moavero, R; Nabbout, R; Riney, K; Sadowski, K; Scholl, T; Sijko, K; Weschke, B; Wojdan, K, 2021) |
| "These children had failed to achieve seizure freedom with available treatment options and were ineligible to participate in randomized controlled trials that only included patients with Lennox-Gastaut and Dravet syndromes." | ( Diamond, MP; Flamini, JR; Linder, DF; Long, SA; Moretz, K; Park, YD; Pope, J, 2020) |
| "Cannabidiol safety, changes in seizure type, frequency, and seizure-free days were evaluated for children aged 1-18 years (at time of consent) as an adjunctive treatment for 36 months." | ( Diamond, MP; Flamini, JR; Linder, DF; Long, SA; Moretz, K; Park, YD; Pope, J, 2020) |
| "Decreases in major seizure frequency and an increase in seizure-free days compared with baseline were reported during treatment." | ( Diamond, MP; Flamini, JR; Linder, DF; Long, SA; Moretz, K; Park, YD; Pope, J, 2020) |
| "Total seizure burden varied widely, with much higher seizure burden in treatment versus control groups (median = 3." | ( Bergin, AM; Dong, M; Fortuno, CR; Hayes, B; Jensen, FE; Krishnamoorthy, K; O'Reilly, D; Rofeberg, V; Singh, A; Soul, JS; Staley, KJ; Stopp, C; Vinks, AA; Wypij, D, 2021) |
| "The antiseizure drugs commonly used as first- and second-line treatments for neonatal seizures display poor efficacy." | ( Culjat, M; Forcelli, PA; Huizenga, MN, 2021) |
| "All untreated rat pups had seizures within 10 minutes after termination of asphyxia." | ( Ala-Kurikka, T; Gailus, B; Hampel, P; Johne, M; Kaila, K; Löscher, W; Römermann, K; Theilmann, W, 2021) |
| "Herein, we investigated the anti-seizure effect by administering KD and a lactic acid bacteria (LAB) in murine model of chemically induced seizures." | ( Eor, JY; Kim, SH; Kwak, MJ; Son, YJ; Tan, PL, 2021) |
| "PB therapy for the management of seizures in newborns and children might be associated with poisoning." | ( Balali-Mood, M; Darchini-Maragheh, E; Ghorani-Azam, A; Riahi-Zanjani, B; Sadeghi, M, 2021) |
| "Electrographic seizure prevalence was 14% (95% confidence interval, 10%-19%; 39/278) in the entire cohort and 13% (95% confidence interval, 7%-21%) in the subgroup of patients meeting the primary outcome of the Established Status Epilepticus Treatment Trial (clinical treatment success within 60 minutes of randomization)." | ( Bleck, TP; Chamberlain, JM; Elm, JJ; Kapur, J; Rosenthal, ES; Shinnar, S; Silbergleit, R; Underwood, E; Zehtabchi, S, 2022) |
| "Electrographic seizures may occur in patients who stop seizing clinically after treatment of convulsive status epilepticus." | ( Bleck, TP; Chamberlain, JM; Elm, JJ; Kapur, J; Rosenthal, ES; Shinnar, S; Silbergleit, R; Underwood, E; Zehtabchi, S, 2022) |
| "We also examined the degree of seizure severity and the modulation of pro-inflammatory cytokines in the treated animals." | ( Bremm Padilha, R; de Lima Rosa, G; Dias de Oliveira Amaral, V; Muliterno Domingues, A; Muller Guzzo, E; Simon Coitinho, A, 2021) |
| "The mean seizure-free time after the sulthiame treatment was 27." | ( Aydın, K; Kılıç, B; Tekin, HG; Topçu, Y; Turanlı, G, 2021) |
| "In the penicillin-induced seizure model, 1, 5, or 10 mg/kg vortioxetine administration significantly decreased mean spike frequency." | ( Aygun, H; Ayyildiz, M, 2021) |
| "Patients had focal-onset seizures despite treatment with one to three ASMs and were 18 years of age and older." | ( Coe, P; Elizebath, R; Gutierrez, EG; Krauss, GL; Yang, J; Zhang, E, 2021) |
| "When administered repeatedly, seizures were suppressed during the entire day." | ( Baekelandt, V; Boon, P; Carrette, E; Delbeke, J; Desloovere, J; Goossens, MG; Larsen, LE; Meurs, A; Raedt, R; Sprengers, M; Van den Haute, C; Vanhove, C; Verstraete, AG; Vonck, K; Wadman, W, 2021) |
| "Such capability can greatly increase seizure freedom rate in surgically treated drug resistant epilepsy cases." | ( Battaglia, DI; Bianchi, F; Chieffo, DPR; Fuggetta, F; Quintiliani, M; Ramaglia, A; Tamburrini, G, 2021) |
| "Rescue therapy for seizure clusters has focused on the use of benzodiazepines." | ( Carrazana, E; Cloyd, J; Haut, S; Rabinowicz, AL, 2021) |
| "In particular, tonic seizures (in a subset of 23 children) were reduced (24-hour tonic seizure count pre-treatment was 8 [4-13] and 3 [1-5] post-treatment EEG#1, p=0." | ( Gofshteyn, JS; Gourley, D; Grinspan, Z; J, JL; K, KG; Marquis, BO; Nangia, S, 2021) |
| "Adults with uncontrolled focal seizures despite treatment with 1-3 antiepileptic drugs/antiseizure medications (AEDs/ASMs) were randomized 1:1:1:1 to placebo or cenobamate 100, 200, or 400 mg once daily." | ( Ferrari, L; Nisman, A; Rosenfeld, WE, 2021) |
| "Steroid treatment may improve seizure outcomes, but the mechanism remains unknown." | ( Jackson, MR; Lee, K; Loring, KE; Mattiske, T; Noebels, JL; Shoubridge, C; Zysk, A, 2021) |
| "In male Wistar rats, seizures were induced with a single administration of pilocarpine (60 mg/kg; i." | ( El-Sahar, AE; El-Sayed, SS; El-Yamany, MF; Salem, HA, 2021) |
| "Patients achieving seizure-freedom during the treatment period were 14." | ( Wang, C; Wang, J; Zhang, L, 2021) |
| "Presentation of first seizure, diagnostic workup, treatment, and impact should be considered individually based on continuously updated knowledge of treating physicians." | ( Carrizosa-Moog, J; Jiménez-Villegas, MJ; Lozano-García, L, 2021) |
| "Minor and major seizures were induced after each MP administration." | ( Frías-Soria, CL; Orozco-Suárez, S; Pérez-Pérez, D; Rocha, L, 2021) |
| "The patients were grouped by seizure subgroups, antiepileptic treatment used, electroencephalography characteristics, and seizure treatment response." | ( Baklan, B; Mermi Dibek, D; Öztura, İ, 2022) |
| "Busulfan is associated with tonic-clonic seizures in ~10% of patients if administered without seizure prophylaxis." | ( Garrity, L; Hughes, K; Lane, A; Nelson, AS; Teusink-Cross, A, 2021) |
| "His blood pressure and seizures were successfully treated during hospital admission, with complete resolution of his neurological deficits." | ( Anne, M; Muralidharan, R; White, JD, 2021) |
| "The antiseizure drug, carbamazepine (CBZ), and the antiabsence drug, ethosuximide (ETX), were administered separately to determine if they selectively suppressed unilateral- versus bilateral-onset SWDs, respectively." | ( Barth, DS; Dudek, FE; Poulsen, DJ; Smith, ZZ; Tatum, S; Taylor, JA, 2021) |
| "Fenfluramine (FFA), an antiseizure medication (ASM) indicated for treating convulsive seizures in Dravet syndrome, was assessed in six patients (five female; 83%) with CDD whose seizures had failed 5-12 ASMs or therapies." | ( Conway, E; Devinsky, O; King, L; Price, D; Schwartz, D, 2021) |
| "For the double-blind studies, baseline seizure frequency, number of baseline AEDs, baseline seizure type, baseline concomitant enzyme-inducing AEDs (EIAEDs), baseline carbamazepine, lamotrigine, or valproic acid, age at diagnosis, time since diagnosis, etiology, and perampanel plasma concentration were included individually with study treatment." | ( Ben-Menachem, E; Krauss, GL; Laurenza, A; Malhotra, M; Patten, A; Wechsler, RT; Williams, B, 2021) |
| "Patients treated 3397 seizure episodes (moderate frequency, 14." | ( Biton, V; Carrazana, E; Cascino, GD; Desai, J; Dlugos, D; Hogan, RE; Liow, K; Mauney, W; Miller, I; Rabinowicz, AL; Segal, EB; Sperling, MR; Tarquinio, D; Vazquez, B; Wheless, JW, 2021) |
| "We analyzed the effect of CBD on seizure frequencies and concomitant antiepileptic drug (AED) use at 1 year after starting treatment and the most recent study visit." | ( Bruno, PL; Fleming, B; Grinspoon, R; Patel, S; Skirvin, LA; Thiele, EA; Wade, C; Wolper, E, 2021) |
| "After re-administration of LCM, the seizures and epileptic discharges clearly disappeared." | ( Maruyama, H; Morino, H; Neshige, S; Ohshita, T; Shishido, T; Ueno, H; Yamada, H, 2021) |
| "Future trials on neonatal antiseizure medication therapy should include continuous electroencephalogram (EEG) monitoring as standard of care and enrol a homogenous population with similar seizure aetiology." | ( Bhulani, A; Hooper, RG; Ramaswamy, VV; Satodia, P; Wahid, RM, 2021) |
| "Data were pooled from patients with focal seizures on 1-2 concomitant antiseizure medications (ASMs) randomized to BRV 50, 100, 200 mg/day, or placebo in 3 phase 3 trials (N01252 [NCT00490035], N01253 [NCT00464269], and N01358 [NCT01261325]) with a 12-week treatment period." | ( Elmoufti, S; Heo, K; Hur, B; Kim, SE; Laloyaux, C; Lee, SA; Lee, SK, 2021) |
| "Oxygen toxicity seizures (OTS) are a well-recognised complication of hyperbaric oxygen treatment (HBOT)." | ( Banham, N; Bonnington, S; Foley, K; Gawthrope, I, 2021) |
| "The rate of oxygen toxicity seizures in a monoplace chamber is not significantly higher than for treatment in the multiplace chamber." | ( Banham, N; Bonnington, S; Foley, K; Gawthrope, I, 2021) |
| "Furthermore, Nestorone treatment caused seizure exacerbation in the WT epileptic animals, but not in the PRKO epileptic animals." | ( Batabyal, T; Joshi, S; Kapur, J; Labuz, A; Shiono, S; Sun, H; Williamson, J, 2021) |
| "Benzodiazepines are the mainstay of seizure rescue medication; for decades, rectally administered diazepam was the only approved rescue medication for seizure clusters outside the hospital setting." | ( Bougher, G; Brooks, L; Dean, P; O'Hara, K; Santilli, N; Shinnar, R, 2021) |
| "Better seizure control was found in children both in the whole cohort (without seizure 49% vs 37% adults), as well as in monotherapy (56% vs 44%), in children with PL 5-20 mg/L vs <5 mg/L (65% vs 44%) and in children with PL 5-10 mg/L vs <2 mg/L (63 vs 14%)." | ( Brozmanova, H; Grundmann, M; Kacirova, I; Koristkova, B, 2022) |
| "The potential antiseizure effects of fenfluramine were first identified in patients with photosensitive epilepsy in the 1980s but it was not rigorously explored as a treatment option until 30 years later." | ( Simmons, R; Sullivan, J, 2021) |
| "Sustained reductions in drop and total seizure frequency were observed for up to 156 weeks, demonstrating long-term benefits of CBD treatment for patients with LGS." | ( Checketts, D; Chin, RF; Devinsky, O; Dunayevich, E; Gil-Nagel, A; Gunning, B; Halford, JJ; Mazurkiewicz-Bełdzińska, M; Mitchell, W; Patel, AD; Scott Perry, M; Thiele, EA; Weinstock, A, 2021) |
| "Neither seizure nor mortality was observed in co-administration of probiotics with DZP." | ( Kangi, S; Najimi, S; Rahimi, HR; Sabouri, S, 2021) |
| "We treated frontal lobe onset seizures with a D2R agonist sumanirole, and it suppressed seizures." | ( Brodovskaya, A; Kapur, J, 2021) |
| "The anti-seizure and anti-depressive effects of 21 days of LCM administration were studied in this model." | ( Agarwal, S; Nirwan, N; Vohora, D; Vyas, P, 2021) |
| "In the acute PTZ convulsion test, treatment with rapamycin showed a significant increase in seizure latency and decreased seizure severity without any change in seizure incidence." | ( Rana, AK; Sharma, A; Sharma, S; Singh, D, 2022) |
| "Real-time continuous tracking of seizure state is necessary to develop feedback neuromodulation therapy that can prevent or terminate a seizure early." | ( Ahmadi, MB; Azgomi, HF; Contreras-Vidal, JL; Craik, A; Faghih, RT; Francis, JT; Parekh, S; Pati, S; Steele, AG, 2021) |
| "Treatment with finasteride increased seizure susceptibility and depression due to decreased progesterone and elevated estrogen levels coupled with decreased monoamine and elevated corticosterone levels." | ( Goel, RK; Pahwa, P; Singh, T, 2022) |
| "Patients with uncontrolled focal seizures taking stable doses of one to three ASMs were administered increasing doses of cenobamate (12." | ( Abou-Khalil, B; Aboumatar, S; Bhatia, P; Biton, V; Klein, P; Krauss, GL; Rosenfeld, WE; Sperling, MR; Vossler, DG; Wechsler, R, 2021) |
| "Patients with uncontrolled focal seizures taking stable doses of 1-3 antiseizure medications (ASMs) were administered increasing daily doses of cenobamate (12." | ( Abou-Khalil, B; Aboumatar, S; Bhatia, P; Biton, V; Ferrari, L; Grall, M; Klein, P; Krauss, GL; Rosenfeld, WE; Sperling, MR; Vossler, DG; Wechsler, R, 2021) |
| "The primary endpoint was seizure-freedom rate during Maintenance Period in the modified Intent-to-Treat (mITT) Analysis Set (patients who had ≥1 post-dose efficacy measurement during Maintenance Period); safety was monitored." | ( Hiramatsu, H; Husni, RE; Ngo, LY; Patten, A; Senokuchi, H; Watanabe, K; Yamamoto, T, 2022) |
| "Initial seizures observed in young rats during the 60 min after administration of pilocarpine (Pilo) were delayed and attenuated by pretreatment with a non-convulsive dose of methionine sulfoximine (MSO)." | ( Albrecht, J; Aldana, BI; Belfiori-Carrasco, LF; Czarnecka, AM; Obara-Michlewska, M; Pawlik, MJ; Popek, MP, 2021) |
| "Phenobarbital was the most common seizure treatment, but seizures were often refractory to initial antiseizure medication." | ( Abend, NS; Bonifacio, S; Chang, T; Chu, C; Cilio, MR; Glass, HC; Lemmon, ME; Massey, SL; McCulloch, CE; Shellhaas, RA; Soul, JS; Thomas, C; Wusthoff, CJ; Xiao, R, 2022) |
| "Regarding time to seizure cessation after midazolam (n = 326) or BDZ (n = 322) administration, there is no significant difference between the two groups {(mean difference = -0." | ( Chhabra, R; Gupta, LK; Gupta, R, 2021) |
| "In case of insufficient seizure control, subsequent treatment phases with other target serum levels followed." | ( Kadish, NE; Lehmann, I; May, TW; Stephani, U; Wiegand, G, 2021) |
| "Many individuals continue to have seizures despite medical and surgical treatments, suggesting new antiepileptic/anticonvulsant drugs are required." | ( Liu, D; Wang, Y, 2022) |
| "In the search for new antiseizure drugs (ASDs) to treat epilepsy, it is yet unclear which types of coumarins are particularly interesting as a systematic analysis has not been reported." | ( Budzyńska, B; Copmans, D; de Witte, PAM; Jóźwiak, K; Kozioł, E; Skalicka-Woźniak, K, 2021) |
| "In about 30% of patients, the seizures are resistant to current treatments; so more effective treatments are urgently needed." | ( Bankstahl, J; Bankstahl, M; Bloms-Funke, P; Kneip, C; Löscher, W; Schröder, W, 2022) |
| "The primary endpoint was a lower focal seizure frequency during the maintenance therapy period." | ( Akiyama, T; Fujita, A; Inoue, Y; Kada, A; Kakita, A; Kato, M; Miyake, N; Nakagawa, E; Saito, AM; Shiraishi, H; Takahashi, Y; Tohyama, J, 2022) |
| "The focal seizure frequency reduced by 25% in all patients during the maintenance therapy period and by a median value of 17%, 28%, and 23% during the 1-4-, 5-8-, and 9-12-week periods." | ( Akiyama, T; Fujita, A; Inoue, Y; Kada, A; Kakita, A; Kato, M; Miyake, N; Nakagawa, E; Saito, AM; Shiraishi, H; Takahashi, Y; Tohyama, J, 2022) |
| "Their demographic findings, seizure aetiology, pre-treatment and post-treatment electroencephalography findings, treatment responses and any side effects of the drugs given were assessed in these patients." | ( Aslan, M; Gungor, S, 2022) |
| "Rate of epileptic seizures after initiation of amantadine treatment was numerically higher in the amantadine group (amantadine: 10." | ( Balk, S; Gerner, ST; Giede-Jeppe, A; Huttner, HB; Jäger, J; Kallmünzer, B; Kuramatsu, JB; Madzar, D; Mueller, T; Rühl, L; Schwab, S; Sembill, JA; Sprügel, MI, 2022) |
| "Overall, median time to seizure cessation from drug administration varied from 2 to 15 min." | ( Aucott, L; Booth, C; Brazzelli, M; Counsell, C; Cruickshank, M; Imamura, M; Manson, P; Scotland, G, 2022) |
| "The proportion of seizure clusters treated with a second dose over time was consistently low across 24 h: 0-4 h, 152 (3." | ( Carrazana, E; Cascino, GD; Dlugos, D; Hogan, RE; Liow, K; Rabinowicz, AL; Sperling, MR; Wheless, JW, 2022) |
| "In addition, seizures were treatable in all patients with PS with a small dose of midazolam (0." | ( Ishiguro, A; Kawakami, S; Kubota, M; Nagata, C; Terashima, H, 2022) |
| "PS was characterized by 1) convulsive seizures shorter than 15 min, 2) seizures treatable with small doses of midazolam, and 3) autonomic symptoms." | ( Ishiguro, A; Kawakami, S; Kubota, M; Nagata, C; Terashima, H, 2022) |
| "The treatment of seizure disorders with currently available pharmacotherapeutic agents is not optimal due to the failure of some patients to respond, coupled with occurrences of side effects." | ( Al-Tannak, NF; Hemdan, A; Kamal, HJ; Phillips, OA, 2022) |
| "Regarding seizure control, it might be suggested that patients with epilepsy treated with PGB should avoid taking CAF." | ( Chwedorowicz, R; Czuczwar, SJ; Raszewski, G; Łukawski, K, 2022) |
| "This antiseizure action was recapitulated when JW-65 was administered after pilocarpine-induced behavioral seizures were well established and was confirmed by time-locked electroencephalographic monitoring and synchronized video." | ( Boda, VK; Hou, R; Jiang, J; Li, L; Li, W; Nagib, MM; Wu, Z; Yasmen, N; Yu, Y; Zhang, S, 2022) |
| "STP effects on absence seizures were quantified by electroencephalographic recording in two animal models: rats treated with a low dose of pentylenetetrazol (20 mg/kg ip) and rats from the WAG/Rij strain." | ( Heulard, I; Reversat, L; Riban, V; Si Hocine, H; Verleye, M, 2022) |
| "To evaluate the effect on seizure frequency of add-on telmisartan treatment in dogs with refractory idiopathic epilepsy." | ( Chai, O; Friedman, A; Gibeon, L; Hanael, E; Konstanitin, L; Rapaport, K; Ruggeri, M; Shamir, MH, 2022) |
| "Telmisartan has the potential to reduce seizure frequency when administered as an add-on antiepileptic drug in dogs with refractory idiopathic epilepsy." | ( Chai, O; Friedman, A; Gibeon, L; Hanael, E; Konstanitin, L; Rapaport, K; Ruggeri, M; Shamir, MH, 2022) |
| "We evaluated the seizure occurrences during 0-3, 4-6, and 7-12 months from the treatment initiation and the last 6 months of the follow-up." | ( Enoki, H; Fujii, Y; Fujimoto, A; Motoi, H; Okanishi, T; Sakuma, S; Shiraishi, H; Yazaki, K, 2022) |
| "Of the patients, 39%, 67% and 72% were seizure-free during 0-3, 4-6, and 7-12 months from treatment initiation, respectively." | ( Enoki, H; Fujii, Y; Fujimoto, A; Motoi, H; Okanishi, T; Sakuma, S; Shiraishi, H; Yazaki, K, 2022) |
| "More than thirty antiseizure medications (ASMs) are available for treating epilepsy." | ( Elmer, S; Reddy, DS, 2022) |
| "The primary outcome was change in convulsive seizure frequency from the pre-treatment baseline to the stable optimal dose phase." | ( Anderson, C; Devinsky, O; Friedman, D; Hamlin, T; Marmanillo, A; Ryan, D; Todd, G; Wilken, P, 2022) |
| "Brivaracetam (BRV) is an anti-seizure drug for the treatment of focal and generalized epileptic seizures shown to augment short-term synaptic fatigue by slowing down synaptic vesicle recycling rates in control animals." | ( Han, X; Sun, Z; Xing, H; Xu, S; Yang, S, 2022) |
| "Secondary outcomes were: seizure freedom, treatment withdrawal for any reason, treatment withdrawal due to adverse events, the proportion of participants who experienced any adverse events, and drug interactions." | ( Bresnahan, R; Marson, AG; Panebianco, M, 2022) |
| "The coil method detected 19-21 Hz seizure activity after PTZ administration." | ( Chang, WJ; Lu, HC; Shyu, BC; Wei Huang, AC, 2022) |
| "We measured seizure reduction, median reduction in seizure frequency, median dose, responder rate, and treatment-emergent adverse events." | ( Karkare, S; Kothare, SV; Shah, YD; Varughese, RT, 2022) |
| "The use of resveratrol in treating seizures has been reported in recent studies." | ( Aggarwal, NB; Akhter, J; Arora, I; Asad, M; Hoda, U; Rastogi, S; Samim, M; Siddiqui, MA, 2022) |
| "We optimized a locomotor-based seizure assay in zebrafish with pentylenetetrazol (PTZ) as the pharmacological proconvulsant to generate a therapeutic window in which proconvulsant-treated zebrafish larvae could be discriminated from a non-treated control." | ( Luyten, W; Panda, SK; Shaw, PAG; Stanca, A, 2022) |
| "PB treatment significantly reduced seizures." | ( Akin, AT; Aygun, H; Karabulut, D; Kızılaslan, N; Sumbul, O, 2023) |
| "Clinical data, frequency of seizure types and treatments were collected from caregivers and medical records in 42 children." | ( Bjurulf, B; Hallböök, T; Kolbjer, S; Reilly, C; Sigurdsson, GV; Thunström, S, 2022) |
| "We review common toxins that cause seizure, their mechanisms, associated toxidromes, and treatments." | ( Phillips, HN; Tormoehlen, L, 2022) |
| "≥50% reduction in drop seizure frequency from baseline and occurrence of treatment-emergent adverse events (TEAEs) were the primary efficacy and safety outcomes." | ( Ameen, R; Bansal, D; Devi, N; Madaan, P; Sahu, JK, 2022) |
| "Efficacy was assessed by comparing seizure frequency before and after initiating STM therapy." | ( Bautista, C; Cachia, P; Caraballo, RH; Espeche, A; Fortini, S; Galicchio, S; Gallo, A; Gamboni, B; Reyes Valenzuela, G; Semprino, M, 2022) |
| "An inadequate seizure occasionally occurs during a course of acute electroconvulsive therapy (ECT) under the maximum approved electrical stimulation in Japan of 504 mC." | ( Gon, J; Iwamoto, T; Kurata, A; Shimizu, H; Wada, K, 2022) |
| "We induced seizure using intravenous administration of PTZ." | ( Amini-Khoei, H; Boroujeni, SN; Lorigooini, Z; Rahimi-Madiseh, M; Taji, M, 2022) |
| "Cenobamate is an antiseizure medication (ASM) approved in Europe as adjunctive therapy for adults with inadequately controlled focal seizures." | ( Ben-Menachem, E; Brandt, C; García Morales, I; Rosenfeld, WE; Santamarina, E; Serratosa, JM; Steinhoff, BJ, 2022) |
| "The primary outcome was the absence of seizures and improvement in the level of consciousness 1 hour after study drug administration." | ( Chamberlain, JM; Coralic, Z; Kapur, J; Olson, KR; Overbeek, D; Silbergleit, R, 2022) |
| "AEDs were administered 30 min before seizure induction once intragastrically at conditionally effective (ED50) and sub-effective (½ ED50) doses: sodium valproate and topiramate - at doses of 300 and 150 mg/kg; levetiracetam - at doses of 100 and 50 mg/kg." | ( Mishchenko, M; Shtrygol, D; Shtrygol, S; Tsyvunin, V, 2022) |
| "Intrathecal administration of antiseizure drugs (ASDs) e." | ( Buschhoff, AS; de Mooij-van Malsen, JG; Scherließ, R; Schiffelholz, T; Stephani, U; Wulff, P, 2022) |
| "The effect of ASDs on seizures measured by the Racine scale is less pronounced in both investigated AD models and suggests that seizures of young AD mice are more difficult to treat." | ( Aourz, N; Barker-Haliski, M; Bjerke, M; De Bundel, D; Engelborghs, S; Nagels, G; Smolders, I; Vande Vyver, M, 2022) |
| "PER was associated with reduction in myoclonic seizure frequency in patients with myoclonic seizures treated in everyday clinical practice." | ( Alsaadi, T; Carreño, M; D'Souza, W; Di Bonaventura, C; McMurray, R; Mohanraj, R; Montoya, J; Shastri, O; Villanueva, V; Yamamoto, T, 2022) |
| "The impact of seizure clusters and the use of intermittent rescue therapy for clusters on the quality of life (QoL) of patients with epilepsy has not been widely studied." | ( Carrazana, E; Cramer, JA; Davis, C; Faught, E; Misra, SN; Rabinowicz, AL, 2022) |
| "In this case, the patient had an epileptic seizure while on enzalutamide treatment." | ( Demir, O; Demirag, G, 2023) |
| "AED prophylaxis in seizure-naïve BTRE patients is not recommended, but AED treatment should be initiated after a first seizure has occurred." | ( Koekkoek, JAF; Taphoorn, MJB; van der Meer, PB, 2022) |
| "The most commonly reported seizure-related benefits (> 50 % of participants) of FFA treatment included a reduction in seizure activity, fewer seizure triggers, and shorter post-ictal recovery." | ( Amtmann, D; Galer, BS; Gammaitoni, AR; Jensen, MP; Salem, R; Wilkie, D, 2022) |
| "Despite introduction of several antiseizure medications over the past two decades, treatment options for childhood absence epilepsy (CAE) and juvenile absence epilepsy (JAE) remain limited." | ( Bast, T; Cleveland, JM; Elshoff, JP; Floricel, F; Morita, D; Schulz, AL, 2022) |
| "Use of EEG capture in addition to seizure diaries offers a robust mechanism of detecting seizure activity and measuring treatment effect." | ( Bast, T; Cleveland, JM; Elshoff, JP; Floricel, F; Morita, D; Schulz, AL, 2022) |
| "The acute seizure in childhood is a medical emergency which is usually managed by benzodiazepines used as a first line of therapy." | ( Ghosh, T; Roy, UK; Rudra, N, 2021) |
| "We evaluated long-term seizure control, for VPA, LEV, LTG mono and combination therapy." | ( Castro, LHM; Pipek, HZ; Pipek, LZ, 2022) |
| "Evidence for treating seizures in AS mainly derives from low-quality studies." | ( Samanta, D, 2022) |
| "There is still no consensus on seizure therapy, owing to poor scientific evidence." | ( Bedetti, L; Berardi, A; Casa Muttini, ED; Cavalleri, F; Ferrari, F; Guidotti, I; Lugli, L; Ori, L; Pugliese, M; Roversi, MF; Stefanelli, F, 2022) |
| "Therapy for neonatal seizures should be prompt and tailored, based on semeiology, mirror of the underlying cause, and cEEG features." | ( Bedetti, L; Berardi, A; Casa Muttini, ED; Cavalleri, F; Ferrari, F; Guidotti, I; Lugli, L; Ori, L; Pugliese, M; Roversi, MF; Stefanelli, F, 2022) |
| "Up to 30% of people with epilepsy have seizures that are resistant to currently available antiepileptic drugs and require treatment with multiple antiepileptic drugs in combination." | ( Bresnahan, R; Dong, J; Geng, J; Martin-McGill, KJ; Ni, H; Shi, LL, 2022) |
| "These seizures result from cyclic changes in circulating progesterone and estradiol levels and there is no effective treatment for this form of intractable epilepsy." | ( Dhillon, HK; Goel, RK; Singh, T, 2022) |
| "Inadequate control of seizures by VPA monotherapy and post-operative status epilepticus are closely related to a significant excitatory rebound after VPA injection (rebound electrodes≧5/64, p = 0." | ( Chen, L; Cui, Z; Guo, Y; Jiang, S; Ke, Z; Liu, Y; Mao, Y; Tong, Y; Wang, D; Wu, Z; Zhang, H; Zhu, Z; Zou, X, 2022) |
| "Progression of seizure severity and duration were compared between treatment groups and wildtype mice (WT)." | ( Chan, J; Jones, NC; Kwan, P; Shen, Y; Silva, JC, 2022) |
| "Beyond effectiveness for aborting seizure clusters, no data exist on how intermittent rescue therapy may impact the long-term natural course of seizure clusters." | ( Carrazana, E; Davis, C; Misra, SN; Peters, JM; Rabinowicz, AL; Rao, VR; Sperling, MR, 2022) |
| "Increased time between seizure clusters may reflect a previously unrecognized beneficial effect of intermittent rescue therapy." | ( Carrazana, E; Davis, C; Misra, SN; Peters, JM; Rabinowicz, AL; Rao, VR; Sperling, MR, 2022) |
| "These electrographic seizures and the ensuing hyperoxic episodes are associated with deficits in working memory and motor coordination that were reversible through attenuation of the posttraumatic and postictal (postseizure) hyperoxia, via administration of a vasoconstricting agent, the calcium channel agonist Bay K8644." | ( Malik, H; Mychasiuk, R; Teskey, GC; Wolff, MD, 2022) |
| "The primary goal of treatment for seizure clusters is cessation of the cluster to avoid progression to more severe conditions, such as prolonged seizures and status epilepticus." | ( Detyniecki, K; Gidal, B, 2022) |
| "Only 67-78% of PWE received anti-seizure medication (ASM) treatment in the community-based studies, mostly monotherapy with phenobarbital, phenytoin or carbamazepine." | ( Amos, A; Escheu, G; Harrison, W; Hauke, P; Kaducu, J; Keller, L; Matuja, W; Ngowi, BJ; Ovuga, E; Pfausler, B; Richter, V; Schmidt, V; Schmutzhard, E; Stelzle, D; Welte, TM; Winkler, AS, 2022) |
| "PWE suffer from high seizure rates and subsequent injuries, as well as from socio-economic consequences due to insufficient ASM treatment." | ( Amos, A; Escheu, G; Harrison, W; Hauke, P; Kaducu, J; Keller, L; Matuja, W; Ngowi, BJ; Ovuga, E; Pfausler, B; Richter, V; Schmidt, V; Schmutzhard, E; Stelzle, D; Welte, TM; Winkler, AS, 2022) |
| "PGES following generalized seizures induced by electroconvulsive therapy (ECT) has been previously linked to antidepressant response." | ( Avidan, MS; Brian Hickman, L; Ching, S; Farber, NB; Guay, CS; Hogan, RE; Huels, ER; Kafashan, M; Kelz, MB; Labonte, AK; Mashour, GA; Maybrier, H; Palanca, BJA; Subramanian, S, 2022) |
| "The total seizure duration in the asphyxia+ganaxolone group was less than the untreated asphyxia group." | ( Allison, BJ; Bennet, L; Boyd, BJ; Castillo-Melendez, M; Fahey, MC; Hirst, JJ; Hunt, RW; Jenkin, G; Malhotra, A; McDonald, C; Mihelakis, J; Miller, SL; Nitsos, I; Pham, Y; Sutherland, AE; Walker, DW; Wong, F; Yawno, T, 2022) |
| "Ganaxolone provided better seizure control than phenobarbital in this perinatal asphyxia model and was neuroprotective for the newborn brain, affording a new therapeutic opportunity for treatment of neonatal seizures." | ( Allison, BJ; Bennet, L; Boyd, BJ; Castillo-Melendez, M; Fahey, MC; Hirst, JJ; Hunt, RW; Jenkin, G; Malhotra, A; McDonald, C; Mihelakis, J; Miller, SL; Nitsos, I; Pham, Y; Sutherland, AE; Walker, DW; Wong, F; Yawno, T, 2022) |
| "Patients with uncontrolled focal seizures taking stable doses of 1-3 antiseizure medications were administered increasing doses of cenobamate (12." | ( Aboumatar, S; Biton, V; Ferrari, L; Rosenfeld, WE; Wechsler, R, 2022) |
| "Quercetin pretreatment alleviates seizure-like behaviors and cognitive impairment in KA-induced epileptic mice." | ( Bentley, R; Hu, G; Jiang, X; Lowe, S; Mei, H; Sun, C; Wu, Y; Xie, R; Zhao, W, 2022) |
| "The maximal seizure stage (SS), stage 2 and 4 latency (S2L, S4L), stage 4 and 5 duration (S4D, S5D), and seizure duration (SD) were all assessed 20 min after PTZ administration by observation." | ( Giahi, M; Hosseinmardi, N; Janahmadi, M; Tavassoli, Z, 2022) |
| "About 7/18 (39%) of patients showed seizure-free with pyridoxine (PN) or pyridoxal-5'-phosphate treatment." | ( Gong, P; Jiao, X; Niu, Y; Xu, Z; Yang, Z; Zhang, Y, 2023) |
| "Exposure, retention, seizure outcomes, and treatment-emergent adverse events (TEAEs) were analyzed." | ( Malhotra, M; Patten, A; Piña-Garza, JE; Rosenfeld, W; Villanueva, V; Yoshinaga, H, 2022) |
| "The median number of seizures per month before CBD treatment was 11, and after CBD treatment was 2." | ( Navarro, CE, 2023) |
| "The incidence of seizure after craniotomy for tumor resection is low regardless of duration of therapy." | ( Cibula, J; Eisenschenk, S; Ghiaseddin, A; Heaton, S; Hodik, M; McGrew, N; Melnick, K; Murad, G; Rahman, M; Roper, S; Smith, J; Wang, Y, 2023) |
| "Perampanel a third-generation antiseizure medication, belongs to a new promising class of drugs called AMPA receptor antagonists, approved to treat focal-onset seizures with or without focal to bilateral tonic clonic seizures and primary generalized tonic-clonic seizures." | ( Abou-Setta, AM; Aboulatta, L; Aloud, B; Askin, N; Eltonsy, S; Lavu, A; Rabbani, R; Shouman, W; Zarychanski, R, 2022) |
| "The key outcomes were reduction in seizure frequency, differences in 50% responder rates, adverse events, and interactions with clobazam as co-therapy." | ( Aparasu, R; Estes, E; Reddy, DS; Talwar, A, 2023) |
| "Novel and effective antiseizure medications are needed to treat refractory and rare forms of epilepsy." | ( Reddy, DS, 2023) |
| "The primary outcome was assigned as the seizure cessation rate within 30 min of the administration of the study drug." | ( Asami, M; Egawa, S; Fukuda, Y; Hoshiyama, E; Inoue, Y; Ishikawa, E; Kaneko, J; Kimura, A; Kondo, Y; Maruo, K; Marushima, A; Matsumaru, Y; Mochizuki, M; Nakamoto, H; Nakamura, K; Takahashi, Y; Uchida, M; Unemoto, K; Yamada, T; Yonekawa, C, 2023) |
| "Differentiating epileptic seizures from other causes of Transient Loss of Consciousness (TLOC) remains a challenge in the Emergency Department (ED), where it may lead to erroneous administration of anti-epileptic drugs." | ( Martinez, S; Patel, J; Pourmand, A; Tran, QK; Wright, H, 2022) |
| "Electroencephalography, seizure diary, patient caregivers' global impression, serum inflammatory markers and neuropsychological evaluation were performed at baseline and after each treatment phase." | ( Ayash, TA; Berrahmoune, S; Corriveau, I; Dassi, C; Myers, KA; Osterman, B; Poulin, C; Schiller, K; Sébire, G; Shevell, MI; Simard-Tremblay, E, 2023) |
| "Treatment of seizure clusters endeavors to prevent additional seizures and avoid progression to conditions such as prolonged seizures and status epilepticus." | ( Gidal, BE; Kotloski, RJ, 2022) |
| "Only rats that presented tonic-clonic seizures during the first 1-5 min after PTZ treatment were included in the study." | ( González-Burgos, I; Guevara, MÁ; Hernández-González, M; Romero-Guerrero, C, 2022) |
| "A total of 1108 seizures were recorded in 130 subjects, of which 110 (65 seizures in 23 subjects in IN group; 45 seizures in 18 subjects in IM group) seizures required midazolam administration and were included in final analysis." | ( Appukuttan, R; Mehta, S; Ramanujan, B; Shaikh, RG; Singh, RK; Tripathi, M; Vibha, D, 2022) |
| "Primary outcome was antiseizure medication (ASM) treatment failure for any reason, and secondary outcomes were treatment failure due to uncontrolled seizures and due to adverse effects." | ( Dirven, L; Koekkoek, JAF; Maschio, M; Taphoorn, MJB; van der Meer, PB, 2023) |
| "Treatment failure due to uncontrolled seizures did not differ significantly between EIASMs and LEV (aHR = 1." | ( Dirven, L; Koekkoek, JAF; Maschio, M; Taphoorn, MJB; van der Meer, PB, 2023) |
| "Primary outcome was antiseizure medication (ASM) treatment failure for any reason, and secondary outcomes were treatment failure due to uncontrolled seizures and due to adverse effects." | ( Dirven, L; Koekkoek, JAF; Maschio, M; Taphoorn, MJB; van der Meer, PB, 2023) |
| "Treatment failure due to uncontrolled seizures did not differ significantly between EIASMs and LEV (aHR = 1." | ( Dirven, L; Koekkoek, JAF; Maschio, M; Taphoorn, MJB; van der Meer, PB, 2023) |
| "Primary outcome was antiseizure medication (ASM) treatment failure for any reason, and secondary outcomes were treatment failure due to uncontrolled seizures and due to adverse effects." | ( Dirven, L; Koekkoek, JAF; Maschio, M; Taphoorn, MJB; van der Meer, PB, 2023) |
| "Treatment failure due to uncontrolled seizures did not differ significantly between EIASMs and LEV (aHR = 1." | ( Dirven, L; Koekkoek, JAF; Maschio, M; Taphoorn, MJB; van der Meer, PB, 2023) |
| "It was shown that the latency of generalized seizures increased after administration of both lamotrigine and LY341495." | ( Bashkatova, VG; Bogdanova, NG; Nazarova, GA; Sudakov, SK, 2022) |
| "It was shown that the latency of generalized seizures increased after administration of both lamotrigine and LY341495." | ( Bashkatova, VG; Bogdanova, NG; Nazarova, GA; Sudakov, SK, 2022) |
| "It was shown that the latency of generalized seizures increased after administration of both lamotrigine and LY341495." | ( Bashkatova, VG; Bogdanova, NG; Nazarova, GA; Sudakov, SK, 2022) |
| "Efficacy variables were derived from seizure-related changes, and tolerability and safety variables from reported treatment-emergent adverse events (TEAEs), BRV withdrawal, and changes to questionnaire scores." | ( Cavill, R; Manuel, M; Naddell, S; Sieradzan, K; White, P, 2023) |
| "Efficacy variables were derived from seizure-related changes, and tolerability and safety variables from reported treatment-emergent adverse events (TEAEs), BRV withdrawal, and changes to questionnaire scores." | ( Cavill, R; Manuel, M; Naddell, S; Sieradzan, K; White, P, 2023) |
| "Recurrence of seizures was observed 30 min after ILE, and the seizures disappeared after re-administration of ILE." | ( Imai, T; Iwabuchi, S; Kinoshita, K; Matsuoka, M, 2023) |
| "Recurrence of seizures was observed 30 min after ILE, and the seizures disappeared after re-administration of ILE." | ( Imai, T; Iwabuchi, S; Kinoshita, K; Matsuoka, M, 2023) |
| "Among neonates with seizures, differences across treatment groups in median maximal hourly seizure burden were assessed using adjusted quantile regression models." | ( Ahmad, KA; Bonifacio, SL; Comstock, BA; Glass, HC; Gonzalez, FF; Heagerty, PJ; Juul, SE; Maitre, N; Massey, SL; Mayock, DE; Mietzsch, U; Natarajan, N; Numis, AL; Sokol, GM; Thomas, C; Van Meurs, KP; Wu, YW; Wusthoff, CJ, 2023) |
| "Among neonates with seizures, differences across treatment groups in median maximal hourly seizure burden were assessed using adjusted quantile regression models." | ( Ahmad, KA; Bonifacio, SL; Comstock, BA; Glass, HC; Gonzalez, FF; Heagerty, PJ; Juul, SE; Maitre, N; Massey, SL; Mayock, DE; Mietzsch, U; Natarajan, N; Numis, AL; Sokol, GM; Thomas, C; Van Meurs, KP; Wu, YW; Wusthoff, CJ, 2023) |
| "Treatment-emergent AEs included seizures (33%), headache (37%), and focal neurologic symptoms (28%)." | ( Abedi, M; Aiken, RD; Bota, DA; Bota, PG; Carrillo, JA; Dillman, RO; Duma, CM; Hsieh, C; Hsu, FPK; Keirstead, HS; Kesari, S; Kong, XT; LaRocca, RV; Nistor, GI; Piccioni, DE; Taylor, TH, 2022) |
| "Treatment-emergent AEs included seizures (33%), headache (37%), and focal neurologic symptoms (28%)." | ( Abedi, M; Aiken, RD; Bota, DA; Bota, PG; Carrillo, JA; Dillman, RO; Duma, CM; Hsieh, C; Hsu, FPK; Keirstead, HS; Kesari, S; Kong, XT; LaRocca, RV; Nistor, GI; Piccioni, DE; Taylor, TH, 2022) |
| "Since arrhythmia often accompanies seizures, patients suffering from epilepsy are frequently co-treated with antiepileptic and antiarrhythmic drugs." | ( Banach, M; Borowicz-Reutt, K, 2022) |
| "The role of stiripentol (STP) in seizure treatment in this population is not well understood." | ( Aungaroon, G; Franz, DN; Horn, PS; Mehta, A, 2023) |
| "Early onset of PTZ-induced seizure-like behavioural scores, the heightened intensity of seizure and reduced latency in different scores were found in PG and CPFX-administered groups." | ( Ramachandran, B; Sivarajan, D, 2023) |
| "The time to reach individual baseline seizure count was longer in patients with focal seizures receiving ESL as a first (Arm 1) versus later (Arm 2) adjunctive therapy (p = 0." | ( Aboumatar, S; Cantu, D; Grinnell, T; Krishnaiengar, SR; Zhang, Y, 2023) |
| "Cenobamate is an antiseizure medication (ASM) approved for the treatment of partial-onset seizures in adults." | ( Bien, CG; Brandt, C; Elakkary, S; Hagemann, A; Klimpel, D, 2023) |
| "In order to induce seizures, PTZ was administered intravenously." | ( Amini-Khoei, H; Korani, MS; Lorigooini, Z; Rahimi-Madiseh, M; Tahmasebi Dehkordi, H; Tavakoli, Z, 2023) |
| "During the motor seizure associated with electroconvulsive therapy (ECT), the muscles of the trunk and limbs contract forcefully and repetitively, predisposing to injuries to muscles, joints, teeth, and bones." | ( Andrade, C, 2023) |
| "In this study, we investigated the antiseizure effects of 5 and 10 mg/kg doses of tacrolimus treatment priorly to pentylenetetrazol (PTZ) induction of seizures in rats." | ( Egilmez, CB; Erbas, O; Erdogan, MA; Pazarlar, BA, 2023) |
| "2-deoxy-D-glucose has acute antiseizure actions in multiple in vivo and in vitro seizure models, including models of SE induced by the chemo convulsants pilocarpine and kainic acid, suggesting that focal enhanced delivery of 2DG to ictal brain circuits is a potential novel anticonvulsant intervention for the treatment of SE." | ( Fountain, NB; Sutula, TP, 2023) |
| "We aimed to explore the possible antiseizure effects of APN pretreatment and underlying molecular mechanisms in a rat model of TLE induced by KA." | ( Ahmadi, S; Hashemi, P, 2023) |
| "These patients received ACTH with antiseizure medication therapy for the first time and were regularly followed up for more than six months at our hospital." | ( Gao, Z; Geng, G; Liu, Y; Meng, Y; Ren, Y; Shi, J; Zhang, H, 2023) |
| "The mean seizure frequency significantly decreased five hours after BRV administration (a 79." | ( Chavarría, B; Principe, A; Rocamora, R; Sanabria, A; Zucca, R, 2023) |
| "From 225 patients, 169 (75%) had good seizure control, with most (60%) receiving monotherapy." | ( Bittar Guaranha, MS; Duarte, JTC; Guilhoto, LM; Hackbart, BA; Marques, VD; Peixoto-Santos, JE; Yacubian, EMT, 2023) |
| "Five individuals had daily seizures at baseline and experienced at least 50% seizure reduction with treatment, sustained in four." | ( Kelly, M; Knight, D; Mahida, S; Olson, HE; Poduri, A, 2023) |
| "The administration of TMP reduced the seizure score and percentage of kindled animals dose-dependently." | ( Danduga, RCSR; Kanakaraju, VK; Kandaswamy, S; Kola, PK; Polopalli, S; Shaik, HB, 2023) |
| "30 min before the seizure-induced procedure, NAC was administered at doses of 300 and 600 mg/kg as pretreatment to investigate anti-seizure and anti-oxidative effects." | ( Azak Pazarlar, B; Bilister Egilmez, C; Erbas, O; Erdogan, MA, 2023) |
| "Efficacy was measured by comparing seizure frequency before and after initiating STM therapy." | ( Adi, J; Cachia, P; Caraballo, R; Chacón, S; Espeche, A; Fortini, S; Galichio, S; Gallo, A; Gamboni, B; Reyes, G; Semprino, M, 2023) |
| "Efficacy was assessed by comparing seizure frequency before and after initiating CBD therapy." | ( Cachia, P; Caraballo, RH; Chacón, S; Espeche, A; Fasulo, L; Fortini, S; Galicchio, S; Gallo, A; Gamboni, B; Reyes Valenzuela, G; Semprino, M; Silva, W, 2023) |
| "Post-traumatic seizure (PTS) prophylaxis is recommended in patients with traumatic brain injury (TBI) at high risk for PTSs, but consensus on the optimal pharmacologic therapy has not yet been established." | ( Atwood, R; Bradley, M; Elster, E; Walker, P; Walper, D, 2023) |
| "Patients with a first unprovoked GTC seizure and evidence of GSWDs on EEG have a high risk of recurrence if left untreated." | ( Beaini, S; Beydoun, A; Hmeimess, G; Hotait, M; Jomaa, N; Nasreddine, W; Wazne, J, 2023) |
| "Spontaneous recurrent seizures appeared only in midazolam-treated rats, at three and six months postexposure in males and only at six months in females." | ( Apland, JP; Aroniadou-Anderjaska, V; Braga, MF; Figueiredo, TH; Rossetti, K, 2023) |
| "However, the seizure onset age, positive WES results, and number of ASMs before PER administration were not significantly." | ( Feng, J; Jin, W; Li, Y; Miao, P; Su, Q; Wang, S; Wang, Y; Xu, S; Yu, L; Zhu, X, 2023) |
| "Mean seizure frequency/28 days in the Full Analysis Set (n = 61) was comparable for adjunctive and monotherapy (0." | ( Kim, DW; Kim, KK; Lee, WG; Lee, Y; Lim, SC; Park, J; Seo, DW; Shon, YM, 2023) |
| "Drug treatment aims to stop eclampsia seizures and prevent reoccurrence of convulsions and complications." | ( Laskowska, M, 2023) |
| "Concomitant antiseizure medications (ASMs) with a statistically significant effect on the apparent systemic clearance (CL/F) of cenobamate in the PopPK model were used to compare simulated patient plasma exposures (area under the plasma concentration vs time curve [AUC]) following monotherapy versus adjunctive therapy." | ( Ferrari, L; Kamin, M; Rosenfeld, WE; Vashi, V, 2023) |
| "At the same points, seizure-free rates of PER monotherapy were 69%, 63% and 52%, and responder rates were 69%, 66% and 61%, respectively." | ( Feng, J; Guo, Y; Miao, P; Xu, S; Xu, ZY; Zheng, Y, 2023) |
| "Patients had good retention, seizure-free and responder rates, and relatively low AEs rate at a low dose of PER treatment." | ( Feng, J; Guo, Y; Miao, P; Xu, S; Xu, ZY; Zheng, Y, 2023) |
| "Severity of seizures were quantified for an hour and treated with midazolam (3 mg/kg, i." | ( Almanza, A; Bryant, E; Carlo, AM; Corson, BE; Gage, M; Kharate, M; Mafuta, C; Massey, N; Meyer, C; Ostrander, M; Rao, NS; Samidurai, M; Showman, L; Thippeswamy, T; Trevino, L; Vasanthi, SS; Wachter, L; Wang, C; Wohlgemuth, M, 2023) |
| "Both seizures and movement disorders can be highly treatment-refractory." | ( Appavu, B; Fahey, MC; Gamble, S; Heim, J; Kim, S; Kruer, MC; Lewis, SA; Mangum, T; Marku, I; Myers, SJ; Pankratz, M; Rosenberg, RB; Shetty, S; Stitt, G; Wilfong, AA; Zhao, N, 2023) |
| "Mean seizure class did not differ between the treatment groups." | ( Ali, I; Brady, RD; Braine, E; Casillas-Espinosa, PM; Cheng, JY; Fukushima, K; Haskali, MB; Hudson, MR; Jones, NC; Jupp, B; Kwan, P; Major, B; Mychasiuk, R; O'Brien, TJ; Sachdev, P; Shultz, SR; Silva, J; Thergarajan, P; Vivash, L; Wright, DK; Yamakawa, GR, 2023) |
| "Finally, convulsions in Toledo voles were reduced or prevented by treatment with the anti-epileptic drug levetiracetam." | ( Burkett, JP; Kile, KB; Lloyd, EAR; Neifer, AE; Neifer, KL; Swain, CC; Wischmeier, JN, 2023) |
| "The average number of seizures per month during the previous 3 months before CNB treatment was 19." | ( Aguilar-Castillo, MJ; Cabezudo-García, P; Carreño, M; Ciano-Petersen, NL; Estivill-Torrús, G; García-Martín, G; Gutierrez-Cardo, AL; López-Moreno, Y; Oliver, B; Ortega-Pinazo, J; Ramírez-García, T; Rodríguez-Uranga, JJ; Romero-Godoy, J; Sanchez-Godoy, L; Serrano-Castro, PJ, 2023) |
| "The median time from urgent seizure onset to IV treatment administration was 60." | ( Asensio, M; Campos, D; Castillo, A; Chavarria, B; Escalza, I; Falip, M; Fernández-Cabrera, A; Garcés, M; García-Morales, I; Gifreu, A; Giménez, J; Guillén, V; Hampel, K; Hernández Pérez, G; Juiz-Fernández, Á; Martínez, AB; Massot, M; Montoya, J; Parejo-Carbonell, B; Rocamora, R; Rodriguez-Osorio, X; Rubio-Nazábal, E; Ruiz-Giménez, J; Santamarina, E; Sayas, D; Villanueva, V, 2023) |
| "Seizure frequency (seizures/month; sz/m), blood tests including concentrations of ZNS and β-hydroxybutyric acid, and owner's visual analogue scale score were collected from all dogs for both treatment periods." | ( Hasegawa, D; Nakatsuka, K; Zanghi, B, 2023) |
| "Besides antiseizure medications, other treatments such as vagal nerve stimulation, responsive neurostimulation, and deep brain stimulation are likely safe." | ( Harris, KM; Hope, OA, 2023) |
| "Tonic-clonic seizures were evoked experimentally in mice after systemic (ip) administration of the respective doses of ISOP, BOR, and classic ASMs." | ( Bojar, H; Chmielewski, J; Florek-Łuszczki, M; Jankiewicz, K; Skalicka-Woźniak, K; Łuszczki, JJ, 2023) |
| "However, with chronic treatment, antiseizure effects are lost as tolerance develops." | ( Deking, L; Feja, M; Felmy, F; Gernert, M; Javadova, A; MacKeigan, D; Meller, S; Veenhuis, A, 2023) |
| "The primary outcome was postoperative seizures occurring within 7 days after surgery, analyzed in both the intention-to-treat and per-protocol populations." | ( Li, S; Liu, M; Peng, Y; Sessler, DI; Wu, Y; Yan, X; Yang, J; Zeng, M; Zhang, L; Zhou, D, 2024) |
| "In neonates who achieve seizure control after the first loading dose of phenobarbital, maintenance therapy compared to no maintenance ASM may have little or no effect on all-cause mortality before discharge, mortality by 18 to 24 months, neurodevelopmental disability by 18 to 24 months and epilepsy post-discharge (low-certainty evidence)." | ( Abiramalatha, T; Brigo, F; Hartmann, H; Pressler, R; Ramaswamy, VV; Thanigainathan, S, 2023) |
| "However, the severity of seizures was significantly reduced after treatment." | ( Diespirov, GP; Griflyuk, AV; Kalita, AD; Postnikova, TY; Sinyak, DS; Zaitsev, AV; Zubareva, OE, 2023) |