| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| Chain A, Cruzipain | 1 | 0 | 0 | 1 |
| RAR-related orphan receptor gamma | 6 | 0 | 0 | 6 |
| SMAD family member 2 | 3 | 0 | 0 | 3 |
| SMAD family member 3 | 3 | 0 | 0 | 3 |
| GLI family zinc finger 3 | 4 | 0 | 0 | 4 |
| AR protein | 5 | 0 | 0 | 5 |
| caspase 7, apoptosis-related cysteine protease | 1 | 0 | 0 | 1 |
| estrogen receptor 2 (ER beta) | 5 | 0 | 0 | 5 |
| nuclear receptor subfamily 1, group I, member 3 | 6 | 0 | 0 | 6 |
| glucocorticoid receptor [Homo sapiens] | 5 | 0 | 0 | 5 |
| retinoic acid nuclear receptor alpha variant 1 | 6 | 0 | 0 | 6 |
| retinoid X nuclear receptor alpha | 6 | 0 | 0 | 6 |
| estrogen-related nuclear receptor alpha | 4 | 0 | 0 | 4 |
| pregnane X nuclear receptor | 5 | 0 | 0 | 5 |
| estrogen nuclear receptor alpha | 4 | 0 | 0 | 4 |
| peroxisome proliferator-activated receptor delta | 4 | 0 | 0 | 4 |
| peroxisome proliferator activated receptor gamma | 4 | 0 | 0 | 4 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | 3 | 0 | 0 | 3 |
| caspase-3 | 1 | 0 | 0 | 1 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 3 | 0 | 0 | 3 |
| Caspase-7 | 2 | 0 | 0 | 2 |
| vitamin D3 receptor isoform VDRA | 3 | 0 | 0 | 3 |
| thyroid hormone receptor beta isoform a | 1 | 0 | 0 | 1 |
| caspase-3 | 2 | 0 | 0 | 2 |
| thyroid hormone receptor beta isoform 2 | 6 | 0 | 0 | 6 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 5 | 0 | 0 | 5 |
| geminin | 4 | 0 | 0 | 4 |
| Voltage-dependent calcium channel gamma-2 subunit | 3 | 0 | 0 | 3 |
| Solute carrier organic anion transporter family member 2B1 | 0 | 0 | 0 | 1 |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 0 | 4 | 0 | 4 |
| Cellular tumor antigen p53 | 6 | 0 | 0 | 6 |
| ATP-dependent translocase ABCB1 | 0 | 4 | 0 | 4 |
| Insulin receptor | 0 | 2 | 0 | 2 |
| Glutamate receptor 2 | 3 | 0 | 0 | 3 |
| Dipeptidyl peptidase 4 | 0 | 1 | 0 | 1 |
| Prostaglandin G/H synthase 2 | 0 | 3 | 0 | 3 |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 0 | 2 | 0 | 2 |
| Histone deacetylase 1 | 0 | 1 | 0 | 1 |
| Histone deacetylase 2 | 0 | 1 | 0 | 1 |
| Solute carrier organic anion transporter family member 1B3 | 0 | 0 | 0 | 1 |
| Histone deacetylase 6 | 0 | 1 | 0 | 1 |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | 0 | 1 | 0 | 1 |
| Solute carrier organic anion transporter family member 1B1 | 0 | 2 | 0 | 3 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 1 | 0 | 0 | 1 |
| USP1 protein, partial | 3 | 0 | 0 | 3 |
| TDP1 protein | 4 | 0 | 0 | 4 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 6 | 0 | 0 | 6 |
| G | 6 | 0 | 0 | 6 |
| cytochrome P450 2D6 | 4 | 0 | 0 | 4 |
| euchromatic histone-lysine N-methyltransferase 2 | 2 | 0 | 0 | 2 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | 5 | 0 | 0 | 5 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | 4 | 0 | 0 | 4 |
| potassium voltage-gated channel subfamily H member 2 isoform d | 3 | 0 | 0 | 3 |
| DNA polymerase kappa isoform 1 | 1 | 0 | 0 | 1 |
| lamin isoform A-delta10 | 3 | 0 | 0 | 3 |
| Interferon beta | 6 | 0 | 0 | 6 |
| HLA class I histocompatibility antigen, B alpha chain | 6 | 0 | 0 | 6 |
| Aldo-keto reductase family 1 member B1 | 0 | 6 | 0 | 6 |
| Alpha-2A adrenergic receptor | 0 | 6 | 0 | 6 |
| Cytochrome P450 2D6 | 0 | 2 | 0 | 2 |
| Acetylcholinesterase | 0 | 2 | 0 | 2 |
| Sodium-dependent noradrenaline transporter | 0 | 6 | 0 | 6 |
| Sodium-dependent serotonin transporter | 0 | 4 | 0 | 4 |
| Enoyl-[acyl-carrier-protein] reductase [NADH] | 0 | 1 | 0 | 1 |
| Inositol hexakisphosphate kinase 1 | 6 | 0 | 0 | 6 |
| Sigma non-opioid intracellular receptor 1 | 0 | 4 | 0 | 4 |
| cytochrome P450 2C9, partial | 6 | 0 | 0 | 6 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | 1 | 0 | 0 | 1 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | 2 | 0 | 0 | 2 |
| Chain A, Ferritin light chain | 2 | 0 | 0 | 2 |
| Luciferase | 1 | 0 | 0 | 1 |
| endonuclease IV | 1 | 0 | 0 | 1 |
| glp-1 receptor, partial | 1 | 0 | 0 | 1 |
| thioredoxin reductase | 1 | 0 | 0 | 1 |
| 15-lipoxygenase, partial | 1 | 0 | 0 | 1 |
| hypoxia-inducible factor 1 alpha subunit | 3 | 0 | 0 | 3 |
| ATAD5 protein, partial | 1 | 0 | 0 | 1 |
| Fumarate hydratase | 2 | 0 | 0 | 2 |
| NFKB1 protein, partial | 1 | 0 | 0 | 1 |
| GLS protein | 1 | 0 | 0 | 1 |
| PPM1D protein | 1 | 0 | 0 | 1 |
| Microtubule-associated protein tau | 1 | 0 | 0 | 1 |
| Thrombopoietin | 1 | 0 | 0 | 1 |
| Smad3 | 2 | 0 | 0 | 2 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 1 | 0 | 0 | 1 |
| thyroid stimulating hormone receptor | 1 | 0 | 0 | 1 |
| progesterone receptor | 2 | 0 | 0 | 2 |
| regulator of G-protein signaling 4 | 2 | 0 | 0 | 2 |
| isocitrate dehydrogenase 1, partial | 1 | 0 | 0 | 1 |
| EWS/FLI fusion protein | 4 | 0 | 0 | 4 |
| nonstructural protein 1 | 1 | 0 | 0 | 1 |
| farnesoid X nuclear receptor | 4 | 0 | 0 | 4 |
| polyprotein | 2 | 0 | 0 | 2 |
| bromodomain adjacent to zinc finger domain 2B | 2 | 0 | 0 | 2 |
| arylsulfatase A | 1 | 0 | 0 | 1 |
| alpha-galactosidase | 1 | 0 | 0 | 1 |
| pyruvate kinase | 1 | 0 | 0 | 1 |
| heat shock protein 90 | 0 | 0 | 1 | 1 |
| IDH1 | 2 | 0 | 0 | 2 |
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 1 | 0 | 0 | 1 |
| calcineurin A1, putative | 0 | 0 | 1 | 1 |
| aryl hydrocarbon receptor | 1 | 0 | 0 | 1 |
| thyroid stimulating hormone receptor | 1 | 0 | 0 | 1 |
| activating transcription factor 6 | 3 | 0 | 0 | 3 |
| thyrotropin-releasing hormone receptor | 1 | 0 | 0 | 1 |
| nuclear receptor subfamily 1, group I, member 2 | 2 | 0 | 0 | 2 |
| Histone H2A.x | 3 | 0 | 0 | 3 |
| beta-2 adrenergic receptor | 0 | 0 | 1 | 1 |
| Bloom syndrome protein isoform 1 | 1 | 0 | 0 | 1 |
| cytochrome P450 2D6 isoform 1 | 1 | 0 | 0 | 1 |
| peripheral myelin protein 22 isoform 1 | 1 | 0 | 0 | 1 |
| cellular tumor antigen p53 isoform a | 1 | 0 | 0 | 1 |
| cytochrome P450 2C19 precursor | 1 | 0 | 0 | 1 |
| cytochrome P450 2C9 precursor | 1 | 0 | 0 | 1 |
| chromobox protein homolog 1 | 1 | 0 | 0 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | 2 | 0 | 0 | 2 |
| heat shock protein beta-1 | 3 | 0 | 0 | 3 |
| huntingtin isoform 2 | 1 | 0 | 0 | 1 |
| mitogen-activated protein kinase 1 | 2 | 0 | 0 | 2 |
| flap endonuclease 1 | 1 | 0 | 0 | 1 |
| ubiquitin carboxyl-terminal hydrolase 2 isoform a | 1 | 0 | 0 | 1 |
| ras-related protein Rab-9A | 1 | 0 | 0 | 1 |
| heat shock protein HSP 90-alpha isoform 2 | 0 | 0 | 0 | 1 |
| urokinase-type plasminogen activator precursor | 2 | 0 | 0 | 2 |
| plasminogen precursor | 2 | 0 | 0 | 2 |
| urokinase plasminogen activator surface receptor precursor | 2 | 0 | 0 | 2 |
| nuclear receptor ROR-gamma isoform 1 | 2 | 0 | 0 | 2 |
| lethal(3)malignant brain tumor-like protein 1 isoform I | 1 | 0 | 0 | 1 |
| peripheral myelin protein 22 | 2 | 0 | 0 | 2 |
| survival motor neuron protein isoform d | 1 | 0 | 0 | 1 |
| cytochrome P450 3A4 isoform 1 | 1 | 0 | 0 | 1 |
| M-phase phosphoprotein 8 | 1 | 0 | 0 | 1 |
| streptokinase A precursor | 0 | 0 | 1 | 1 |
| muscarinic acetylcholine receptor M1 | 1 | 0 | 0 | 1 |
| neuropeptide S receptor isoform A | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | 1 | 0 | 0 | 1 |
| Solute carrier family 22 member 1 | 0 | 1 | 0 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | 2 | 0 | 0 | 2 |
| Intermediate conductance calcium-activated potassium channel protein 4 | 0 | 1 | 0 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 4 | 0 | 2 | 0 | 2 |
| Transient receptor potential cation channel subfamily M member 2 | 0 | 1 | 0 | 1 |
| Bile salt export pump | 0 | 3 | 0 | 3 |
| Epidermal growth factor receptor | 0 | 1 | 0 | 1 |
| Chymotrypsinogen A | 0 | 1 | 0 | 1 |
| Beta-lactamase | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 2 | 0 | 1 | 0 | 1 |
| Glucocorticoid receptor | 0 | 2 | 0 | 2 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 0 | 1 | 0 | 1 |
| Receptor tyrosine-protein kinase erbB-2 | 0 | 1 | 0 | 1 |
| Steroid 17-alpha-hydroxylase/17,20 lyase | 0 | 1 | 0 | 1 |
| Integrin beta-3 | 1 | 0 | 0 | 1 |
| Histidine-rich protein PFHRP-II | 0 | 1 | 0 | 1 |
| Estrogen receptor | 0 | 0 | 1 | 1 |
| Tyrosine-protein kinase Fyn | 0 | 1 | 0 | 1 |
| Heme oxygenase 1 | 0 | 1 | 0 | 1 |
| ATP-dependent translocase ABCB1 | 0 | 2 | 0 | 2 |
| Epoxide hydrolase 1 | 0 | 0 | 0 | 1 |
| Glycine receptor subunit alpha-1 | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M2 | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M4 | 0 | 2 | 0 | 2 |
| Integrin alpha-IIb | 1 | 0 | 0 | 1 |
| Beta-1 adrenergic receptor | 0 | 2 | 0 | 2 |
| Cytochrome P450 3A4 | 0 | 2 | 0 | 3 |
| Adenosine receptor A3 | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M1 | 0 | 2 | 0 | 2 |
| Aromatase | 0 | 1 | 0 | 1 |
| Cytochrome P450 2C9 | 0 | 2 | 1 | 3 |
| Beta-3 adrenergic receptor | 0 | 2 | 0 | 2 |
| D(2) dopamine receptor | 0 | 2 | 0 | 2 |
| Androgen receptor | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 1 | 0 | 0 | 1 |
| Alpha-1B adrenergic receptor | 0 | 2 | 0 | 2 |
| Alpha-2B adrenergic receptor | 0 | 2 | 0 | 2 |
| Potassium-transporting ATPase subunit beta | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 1 | 0 | 0 | 1 |
| Potassium-transporting ATPase alpha chain 1 | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 1A | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 1 | 0 | 0 | 1 |
| Muscarinic acetylcholine receptor M3 | 0 | 2 | 0 | 2 |
| Glycine receptor subunit beta | 0 | 2 | 0 | 2 |
| ATP-dependent translocase ABCB1 | 0 | 2 | 0 | 2 |
| Substance-K receptor | 0 | 2 | 0 | 2 |
| D(1A) dopamine receptor | 0 | 2 | 0 | 2 |
| D(4) dopamine receptor | 0 | 2 | 0 | 2 |
| Potassium voltage-gated channel subfamily A member 3 | 0 | 1 | 0 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | 0 | 1 | 0 | 1 |
| Glycine receptor subunit alpha-2 | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 1 | 0 | 0 | 1 |
| Heme oxygenase 2 | 0 | 1 | 0 | 1 |
| Glycine receptor subunit alpha-3 | 0 | 2 | 0 | 2 |
| Thromboxane-A synthase | 0 | 1 | 0 | 1 |
| Histamine H2 receptor | 0 | 2 | 0 | 2 |
| C-X-C chemokine receptor type 1 | 0 | 1 | 0 | 1 |
| Alpha-1D adrenergic receptor | 0 | 2 | 0 | 2 |
| Substance-P receptor | 0 | 2 | 0 | 2 |
| Platelet-activating factor receptor | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 2A | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 2C | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 1 | 0 | 0 | 1 |
| 5-hydroxytryptamine receptor 1B | 0 | 2 | 0 | 2 |
| Indoleamine 2,3-dioxygenase 1 | 0 | 1 | 0 | 1 |
| Adenosine receptor A2a | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 1 | 0 | 0 | 1 |
| Vasopressin V2 receptor | 0 | 1 | 0 | 1 |
| Adenosine receptor A1 | 0 | 2 | 0 | 2 |
| Cytochrome P450 2C19 | 0 | 2 | 0 | 2 |
| Histamine H1 receptor | 0 | 2 | 0 | 2 |
| Mu-type opioid receptor | 0 | 2 | 0 | 2 |
| D(3) dopamine receptor | 0 | 2 | 0 | 2 |
| Alpha-synuclein | 1 | 0 | 0 | 1 |
| Malate dehydrogenase, cytoplasmic | 0 | 1 | 0 | 1 |
| Delta-type opioid receptor | 0 | 2 | 0 | 2 |
| Kappa-type opioid receptor | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 2B | 0 | 2 | 0 | 2 |
| Alpha-1A adrenergic receptor | 0 | 2 | 0 | 2 |
| Histamine H2 receptor | 2 | 0 | 0 | 2 |
| 5-hydroxytryptamine receptor 6 | 0 | 2 | 0 | 2 |
| C-C chemokine receptor type 4 | 0 | 1 | 0 | 1 |
| Transitional endoplasmic reticulum ATPase | 0 | 1 | 0 | 1 |
| Spike glycoprotein | 4 | 0 | 0 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 1 | 0 | 0 | 1 |
| Guanine nucleotide-binding protein G | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 1 | 0 | 0 | 1 |
| Disintegrin and metalloproteinase domain-containing protein 17 | 1 | 0 | 0 | 1 |
| Cytochrome P450 144 | 0 | 0 | 3 | 3 |
| Steroid C26-monooxygenase | 0 | 0 | 3 | 3 |
| Cytochrome P450 130 | 0 | 0 | 1 | 1 |
| Cytochrome P450 130 | 0 | 0 | 1 | 1 |
| Steroid C26-monooxygenase | 0 | 0 | 3 | 3 |
| Mycocyclosin synthase | 0 | 0 | 1 | 1 |
| Lanosterol 14-alpha demethylase | 0 | 0 | 1 | 1 |
| Sodium-dependent dopamine transporter | 0 | 2 | 0 | 2 |
| Potassium voltage-gated channel subfamily H member 2 | 0 | 2 | 0 | 2 |
| TAR DNA-binding protein 43 | 2 | 0 | 0 | 2 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | 0 | 2 | 0 | 2 |
| Nuclear receptor subfamily 1 group I member 3 | 0 | 2 | 0 | 2 |
| Lanosterol 14-alpha demethylase | 0 | 1 | 0 | 1 |
| Sterol 14-alpha demethylase | 0 | 0 | 2 | 2 |
| Estrogen receptor beta | 0 | 0 | 1 | 1 |
| Indoleamine 2,3-dioxygenase 2 | 0 | 1 | 0 | 1 |
| Rap guanine nucleotide exchange factor 4 | 1 | 0 | 0 | 1 |
| GABA theta subunit | 1 | 0 | 0 | 1 |
| ATPase family AAA domain-containing protein 5 | 2 | 0 | 0 | 2 |
| Bile acid receptor | 0 | 1 | 0 | 1 |
| 14-alpha sterol demethylase | 0 | 0 | 2 | 2 |
| Ataxin-2 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit epsilon | 1 | 0 | 0 | 1 |
| Cysteinyl leukotriene receptor 1 | 0 | 2 | 0 | 2 |
| HSP40, subfamily A [Plasmodium falciparum 3D7] | 0 | 0 | 0 | 1 |
| heat shock protein 90, putative | 0 | 0 | 0 | 1 |
| ATP-dependent phosphofructokinase | 1 | 0 | 0 | 1 |
| GALC protein | 1 | 0 | 0 | 1 |
| Chain A, Beta-lactamase | 1 | 0 | 0 | 1 |
| PINK1 | 1 | 0 | 0 | 1 |
| Parkin | 1 | 0 | 0 | 1 |
| photoreceptor-specific nuclear receptor | 0 | 1 | 0 | 1 |
| serine/threonine-protein kinase PLK1 | 1 | 0 | 0 | 1 |
| transactivating tegument protein VP16 [Human herpesvirus 1] | 0 | 1 | 0 | 1 |
| DNA dC->dU-editing enzyme APOBEC-3G isoform 1 | 1 | 0 | 0 | 1 |
| ATP-binding cassette sub-family C member 3 | 0 | 2 | 0 | 2 |
| Multidrug resistance-associated protein 4 | 0 | 2 | 0 | 2 |
| Nuclear receptor subfamily 4 group A member 2 | 0 | 0 | 1 | 1 |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 0 | 1 | 0 | 1 |
| Sigma non-opioid intracellular receptor 1 | 0 | 1 | 0 | 1 |
| Canalicular multispecific organic anion transporter 1 | 0 | 2 | 0 | 2 |
| cystic fibrosis transmembrane conductance regulator | 0 | 1 | 0 | 1 |
| C-8 sterol isomerase | 0 | 1 | 0 | 1 |
| Squalene monooxygenase | 0 | 1 | 0 | 1 |
| Squalene monooxygenase | 0 | 2 | 0 | 2 |
| 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase | 0 | 1 | 0 | 1 |
| Sterol 14-alpha-demethylase | 0 | 0 | 1 | 1 |
| 14-alpha sterol demethylase | 0 | 0 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1F | 0 | 1 | 0 | 1 |
| Cholesterol side-chain cleavage enzyme, mitochondrial | 0 | 0 | 1 | 1 |
| Lanosterol 14-alpha demethylase | 0 | 0 | 1 | 1 |
| Cytochrome P450 2B6 | 0 | 1 | 0 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1D | 0 | 1 | 0 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1S | 0 | 1 | 0 | 1 |
| 14-alpha sterol demethylase | 0 | 0 | 1 | 1 |
| Cholesterol 24-hydroxylase | 0 | 2 | 1 | 3 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |