Telangiectasia, Hereditary Hemorrhagic

An autosomal dominant vascular anomaly characterized by telangiectases of the skin and mucous membranes and by recurrent gastrointestinal bleeding. This disorder is caused by mutations of a gene (on chromosome 9q3) which encodes endoglin, a membrane glycoprotein that binds TRANSFORMING GROWTH FACTOR BETA.

Synonym
Telangiectasia, Hereditary Hemorrhagic

Excerpt	Reference
"Hereditary hemorrhagic telangiectasia is an autosomal inherited defect."	( Berlin, MS; Cahan, LD; Hieshima, GB; Pribram, HW, 1977)
"Hereditary hemorrhagic telangiectasia is a rare autosomal dominant inherited disease characterized by vascular dysplasia."	( Bloomfield, GS; Kiyeng, JC; Koech, C; Siika, A, 2016)
"Hereditary hemorrhagic telangiectasia is an autosomal dominant vascular disorder caused by heterozygous, loss-of-function mutations in 4 transforming growth factor beta (TGFβ) pathway members, including the central transcriptional mediator of the TGFβ pathway, Smad4."	( Crist, AM; Garai, J; Klein, C; Lee, AR; Meadows, SM; Thoele, J; Ullmer, C; Zabaleta, J; Zhou, X, 2019)
"Hereditary hemorrhagic telangiectasia is a rare vascular genetic disease."	( Beaudoin, M; Bergerot, C; Bréant, V; Colombet, B; Decullier, E; Dupuis-Girod, S; Fargeton, AE; Faure, F; Letievant, JC; Philouze, P; Pitiot, V, 2019)

Excerpt	Reference
"Hereditary hemorrhagic telangiectasia has been underreported for many years."	( Collins, C; Flanagan, BA; Parra, S, 2012)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	137 (27.35)	23.3326
1990's	38 (7.58)	12.5806
2000's	121 (24.15)	18.1394
2010's	162 (32.34)	28.8240
2020's	43 (8.58)	9.53

Drug	Relationship Strength	Studies	Trials
ammonium hydroxide	low	3	0
beta-alanine	low	1	0
salicylic acid	low	2	0
dimethyl sulfoxide	low	1	0
dalteparin	low	1	0
histamine	low	2	0
phytic acid	low	2	0
niacinamide	low	1	0
niacin	low	2	0
nitrites	low	1	0
4-aminobenzoic acid	low	1	0
acetaminophen	low	1	0
diatrizoic acid	low	2	0
aspirin	low	9	0
bupivacaine	low	1	0
busulfan	low	1	0
caffeine	low	1	0
carbazochrome	medium	2	1
cimetidine	low	1	0
citalopram	low	1	0
clonidine	low	1	0
cyclofenil	low	1	0
cyproheptadine	low	1	0
diphenhydramine	low	1	0
dipyridamole	low	1	0
fenfluramine	low	1	0
fluorouracil	low	2	0
furosemide	low	1	0
gentamicin	low	2	0
halothane	low	1	0
iofetamine	low	1	0
iohexol	low	1	0
iothalamic acid	low	1	0
ioversol	low	1	0
2-propanol	low	1	0
metformin	low	1	0
metronidazole	low	1	0
activins	low	1	0
nifedipine	low	1	0
oxymetazoline	low	1	0
krypton	low	1	0
thalidomide	medium	29	1
ticlopidine	low	1	0
tranexamic acid	medium	24	3
estriol	medium	8	3
floxuridine	low	1	0
norethindrone acetate	low	1	0
lynestrenol	low	1	0
prednisone	low	4	0
adrenochrome	medium	2	1
alanine	low	1	0
aspartic acid	low	2	0
ethinyl estradiol	medium	10	1
aminopyrine	low	1	0
methyltestosterone	low	2	0
adenosine diphosphate	low	2	0
bromodeoxyuridine	low	1	0
phenylephrine	low	1	0
tyrosine	low	1	0
methylene blue	low	1	0
norethindrone	medium	4	1
norethynodrel	low	5	0
histidine	low	1	0
threonine	low	1	0
mestranol	low	6	0
tryptophan	low	1	0
isoleucine	low	1	0
pantothenic acid	medium	1	1
pyrroles	low	1	0
meglumine	low	2	0
indazoles	medium	6	1
alpha-aminopyridine	low	1	0
acetylcysteine	medium	1	1
vancomycin	low	1	0
aminorex	low	1	0
fluorescein	low	1	0
sulfur hexafluoride	low	1	0
doxifluridine	low	1	0
enbucrilate	low	2	0
iridium	low	3	0
manganese	low	7	0
neodymium	low	2	0
platinum	medium	1	1
technetium	low	5	0
titanium	low	1	0
tungsten	low	1	0
argon	medium	7	1
gadolinium	low	1	0
holmium	low	1	0
yttrium	low	2	0
ferrous sulfate	medium	4	1
silver nitrate	low	1	0
trolamine salicylate	low	2	0
tetradecanoylphorbol acetate	low	1	0
danazol	low	1	0
carbimazole	low	1	0
4-methoxyamphetamine	low	1	0
transferrin	medium	3	1
glucaric acid	low	1	0
amoxicillin	low	2	0
sq-11725	low	1	0
ng-nitroarginine methyl ester	low	2	0
propiconazole	low	2	0
paroxetine	low	1	0
simvastatin	low	1	0
raloxifene hydrochloride	low	1	0
cicletanine	low	1	0
itraconazole	medium	1	1
clopidogrel	low	1	0
dexfenfluramine	low	1	0
iridium radioisotopes	low	2	0
xenon radioisotopes	low	1	0
3,7-dimethyl-7-octen-1-ol	low	1	0
nicotine	low	1	0
fibrinogen	low	5	0
pyrimidine dimers	low	1	0
glucuronic acid	low	1	0
bosentan anhydrous	low	4	0
dexpanthenol	medium	1	1
bazedoxifene	low	1	0
lactitol	low	1	0
erlotinib hydrochloride	low	1	0
dabigatran	low	2	0
sorafenib	low	1	0
lenalidomide	low	1	0
cortisone	low	2	0
trimethoprim, sulfamethoxazole drug combination	low	1	0
fibrin	low	1	0
bradykinin	low	1	0
elastin	low	2	0
inositol 3-phosphate	low	14	0
betadex	low	1	0
tacrolimus	low	2	0
afimoxifene	low	1	0
melphalan	low	1	0
flavin-adenine dinucleotide	low	1	0
polidocanol	low	4	0
ferlixit	low	1	0
leuprolide	low	1	0
dienestrol	low	1	0
tamoxifen	medium	9	2
nadp	low	1	0
ranitidine	low	1	0
nitinol	low	2	0
alpha-chymotrypsin	low	1	0
bilirubin	low	1	0
dinoprostone	low	1	0
11-cis-retinal	low	1	0
rutin	low	7	0
zeaxanthin	medium	1	1
genistein	low	1	0
clavulanic acid	low	1	0
zinostatin	low	1	0
phenylephrine hydrochloride	low	27	0
sirolimus	low	2	0
deamino arginine vasopressin	low	2	0
iloprost	low	1	0
n-(n-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester	low	1	0
su 11248	low	1	0
aluminum	low	2	0
cysteine	low	2	0
radium	low	2	0
aminorex fumarate	low	1	0
everolimus	low	1	0
axitinib	low	1	0
gadolinium dtpa	low	2	0
beraprost	low	1	0
u 62840	low	1	0
lu 208075	low	2	0
hydralazine 4-anisaldehyde hydrazone	low	1	0
amoxicillin-potassium clavulanate combination	low	1	0
ezetimibe, simvastatin drug combination	low	1	0
rivaroxaban	low	2	0
apixaban	low	1	0
technetium tc 99m disofenin	low	1	0
indocyanine green	low	1	0
nad	low	1	0
buparlisib	low	1	0
sodium tetradecyl sulfate	medium	1	1
ro13-9904	low	1	0
glycolipids	low	1	0
interleukin-8	low	1	0
natriuretic peptide, brain	low	1	0
ascorbic acid	low	2	0
dicumarol	low	1	0
warfarin	low	5	0
phenprocoumon	low	1	0
transforming growth factor beta	low	78	0
technetium tc 99m sulfur colloid	low	1	0
ferric oxide, saccharated	low	1	0
adrenomedullin	low	1	0
thromboplastin	low	1	0
levoleucovorin	low	1	0
folic acid	low	1	0
sildenafil citrate	low	2	0
nintedanib	low	2	0
eye	low	11	0

Protein Targets (1,806)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, Retinaldehyde-binding protein 1	0	0	1	1
Chain A, Retinaldehyde-binding protein 1	0	0	1	1
hypoxia-inducible factor 1 alpha subunit	19	0	0	19
RAR-related orphan receptor gamma	45	0	0	45
GLI family zinc finger 3	49	0	0	49
AR protein	67	0	0	67
aldehyde dehydrogenase 1 family, member A1	32	0	0	32
retinoic acid nuclear receptor alpha variant 1	53	0	0	53
retinoid X nuclear receptor alpha	40	0	0	40
estrogen nuclear receptor alpha	77	0	0	77
peroxisome proliferator-activated receptor delta	26	0	0	26
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	31	0	0	31
activating transcription factor 6	24	0	0	24
v-jun sarcoma virus 17 oncogene homolog (avian)	29	0	0	29
Histone H2A.x	20	0	0	20
thyroid hormone receptor beta isoform a	18	0	0	18
heat shock protein beta-1	22	0	0	22
nuclear factor erythroid 2-related factor 2 isoform 1	47	0	0	47
lamin isoform A-delta10	35	0	0	35
Voltage-dependent calcium channel gamma-2 subunit	29	0	0	29
Glutamate receptor 2	29	0	0	29
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	27	0	0	27
Genome polyprotein	0	0	1	1
USP1 protein, partial	21	0	0	21
thyroid stimulating hormone receptor	23	0	0	23
glucocorticoid receptor [Homo sapiens]	53	0	0	53
chromobox protein homolog 1	21	0	0	21
transcriptional regulator ERG isoform 3	5	0	0	5
geminin	49	0	0	49
Polyphenol oxidase 2	0	5	0	7
Cellular tumor antigen p53	43	0	0	43
Thiopurine S-methyltransferase	0	1	0	1
Succinate-semialdehyde dehydrogenase, mitochondrial	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Cytochrome P450 1B1	0	2	0	2
Dihydropteroate synthase	0	0	1	1
5-hydroxytryptamine receptor 2C	0	2	1	3
5-hydroxytryptamine receptor 2A	0	5	1	6
5-hydroxytryptamine receptor 1A	0	16	4	21
5-hydroxytryptamine receptor 1B	0	15	2	17
5-hydroxytryptamine receptor 1D	0	1	2	3
5-hydroxytryptamine receptor 1F	0	1	2	3
5-hydroxytryptamine receptor 2B	0	2	1	3
5-hydroxytryptamine receptor 6	0	0	1	1
Sodium-dependent serotonin transporter	0	21	3	24
Sodium-dependent serotonin transporter	0	7	2	9
5-hydroxytryptamine receptor 7	0	1	1	2
5-hydroxytryptamine receptor 5A	0	0	1	1
5-hydroxytryptamine receptor 5B	0	0	1	1
5-hydroxytryptamine receptor 3A	0	0	1	1
5-hydroxytryptamine receptor 4	0	0	1	1
5-hydroxytryptamine receptor 3B	0	0	1	1
ATAD5 protein, partial	15	0	0	15
GLS protein	16	0	0	16
Microtubule-associated protein tau	26	0	0	26
Smad3	12	0	0	12
nuclear receptor subfamily 1, group I, member 3	40	0	0	40
progesterone receptor	34	0	0	34
EWS/FLI fusion protein	32	0	0	32
estrogen-related nuclear receptor alpha	53	0	0	53
peroxisome proliferator activated receptor gamma	36	0	0	36
aryl hydrocarbon receptor	15	0	0	15
thyroid hormone receptor beta isoform 2	54	0	0	54
peripheral myelin protein 22	22	0	0	22
cytochrome P450 3A4 isoform 1	16	0	0	16
Gamma-aminobutyric acid receptor subunit pi	16	1	2	19
ATP-binding cassette sub-family C member 3	0	31	0	31
Multidrug resistance-associated protein 4	0	31	0	33
Solute carrier family 22 member 6	0	7	0	7
Carbonic anhydrase 12	0	3	0	9
UDP-glucuronosyltransferase 1A9	0	0	0	1
Bile salt export pump	0	10	0	10
Bile salt export pump	0	52	0	52
Cytochrome P450 2B1	0	1	0	2
Cytochrome P450 1A1	0	0	0	1
Carbonic anhydrase 1	0	10	0	19
Carbonic anhydrase 2	0	10	0	20
Myoglobin	0	1	0	1
Cytochrome P450 1A1	0	0	1	2
Cytochrome P450 1A2	0	5	0	6
Prostaglandin G/H synthase 1	0	4	0	4
Carbonic anhydrase 3	0	3	0	8
Cytochrome P450 3A4	0	18	1	19
Cytochrome P450 2D6	0	10	1	11
Cytochrome P450 2C9	0	15	1	16
Polyunsaturated fatty acid lipoxygenase ALOX15	0	6	0	6
Gamma-aminobutyric acid receptor subunit beta-1	16	1	2	19
Sulfotransferase 1A1	0	0	0	1
Gamma-aminobutyric acid receptor subunit delta	16	1	2	19
Gamma-aminobutyric acid receptor subunit gamma-2	16	1	2	19
UDP-glucuronosyltransferase 1-6	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	16	1	2	19
Gamma-aminobutyric acid receptor subunit alpha-3	16	1	2	19
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	1	0	3
Carbonic anhydrase 4	0	4	0	10
Prostaglandin G/H synthase 1	0	6	0	6
Carbonic anhydrase 6	0	3	0	9
Gamma-aminobutyric acid receptor subunit gamma-1	16	1	2	19
Gamma-aminobutyric acid receptor subunit alpha-2	16	1	2	19
Gamma-aminobutyric acid receptor subunit alpha-4	16	1	2	19
Gamma-aminobutyric acid receptor subunit gamma-3	16	1	2	19
Gamma-aminobutyric acid receptor subunit alpha-6	16	1	2	19
Carbonic anhydrase 5A, mitochondrial	0	3	0	9
Prostaglandin G/H synthase 2	0	4	5	10
Carbonic anhydrase 7	0	4	0	10
Nuclear receptor ROR-gamma	9	0	0	9
Cytochrome P450 2J2	0	11	0	11
Gamma-aminobutyric acid receptor subunit alpha-1	16	2	2	20
Gamma-aminobutyric acid receptor subunit beta-3	16	1	2	19
Gamma-aminobutyric acid receptor subunit beta-2	16	1	2	19
Carbonic anhydrase 9	0	5	0	11
GABA theta subunit	16	1	2	19
Canalicular multispecific organic anion transporter 1	0	30	0	30
Carbonic anhydrase 15	0	3	0	7
Carbonic anhydrase 13	0	3	0	8
Gamma-aminobutyric acid receptor subunit epsilon	16	1	2	19
Carbonic anhydrase 14	0	3	0	9
Carbonic anhydrase 5B, mitochondrial	0	3	0	9
toxin B	0	0	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	11	0	0	11
Chain A, 2-oxoglutarate Oxygenase	15	0	0	15
Chain A, ATP-DEPENDENT DNA HELICASE Q1	5	0	0	5
acetylcholinesterase	19	0	0	19
dopamine D1 receptor	3	0	0	3
15-lipoxygenase, partial	7	0	0	7
pregnane X receptor	12	0	0	12
phosphopantetheinyl transferase	21	0	0	21
NFKB1 protein, partial	6	0	0	6
Thrombopoietin	6	0	0	6
regulator of G-protein signaling 4	15	0	0	15
farnesoid X nuclear receptor	35	0	0	35
vitamin D (1,25- dihydroxyvitamin D3) receptor	30	0	0	30
arylsulfatase A	14	0	0	14
euchromatic histone-lysine N-methyltransferase 2	41	0	0	41
Bloom syndrome protein isoform 1	12	0	0	12
D(1A) dopamine receptor	10	0	0	10
flap endonuclease 1	9	0	0	9
survival motor neuron protein isoform d	16	0	0	16
muscarinic acetylcholine receptor M1	14	0	0	14
Histone deacetylase 3	0	1	0	1
Histone deacetylase 4	0	1	0	1
Guanine nucleotide-binding protein G	4	0	0	4
Histone deacetylase 1	0	1	0	1
Histone deacetylase 7	0	1	0	1
Histone deacetylase 2	0	1	0	1
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 11	0	1	0	1
Ataxin-2	30	0	0	30
Histone deacetylase 8	0	1	0	1
Histone deacetylase 6	0	1	0	1
Histone deacetylase 9	0	1	0	1
Histone deacetylase 5	0	1	0	1
ATP-dependent phosphofructokinase	17	0	0	17
Chain A, Heat Shock Protein 90	0	0	1	1
Chain A, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain B, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, Myosin Ie Heavy Chain	0	0	1	1
Chain A, Preprotein translocase secA	0	0	1	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Phosphoribosylformylglycinamidine synthase	0	1	0	1
Chain A, nucleoside diphosphate kinase A	0	0	1	1
Chain B, nucleoside diphosphate kinase A	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A, Kinesin-like protein KIF11	0	1	0	1
HPr kinase/phosphorylase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 7	0	0	6	6
ATP-dependent molecular chaperone HSP82	0	0	0	1
Heat shock protein HSP 90-alpha	0	1	3	5
Heat shock protein HSP 90-beta	0	1	1	3
2-dehydropantoate 2-reductase	0	1	1	2
Heat shock 70 kDa protein 1A	0	1	1	2
Endoplasmic reticulum chaperone BiP	0	0	1	1
Heat shock cognate 71 kDa protein	0	0	1	1
Pyruvate kinase PKM	0	0	0	1
Pyruvate kinase PKLR	0	0	0	1
Endoplasmin	0	0	0	1
Heat shock cognate 71 kDa protein	0	0	1	1
5'-nucleotidase	0	1	0	1
Mu-type opioid receptor	0	7	2	9
Delta-type opioid receptor	0	3	2	5
Kappa-type opioid receptor	0	7	2	9
Endoplasmin	0	1	1	2
P2Y purinoceptor 2	0	0	1	1
Phosphatidylinositol 4-kinase alpha	0	3	0	3
P2X purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2X purinoceptor 1	0	0	1	1
P2X purinoceptor 4	0	1	1	2
P2X purinoceptor 5	0	0	1	1
P2X purinoceptor 6	0	0	1	1
P2X purinoceptor 3	0	0	1	1
Inositol monophosphatase 1	8	0	0	8
Heat shock protein 75 kDa, mitochondrial	0	1	0	1
P2Y purinoceptor 6	0	0	1	1
Phosphatidylinositol 4-kinase type 2-beta	0	3	0	3
P2Y purinoceptor 11	0	0	1	1
Phosphatidylinositol 4-kinase type 2-alpha	0	3	0	3
P2Y purinoceptor 12	0	0	1	1
Sensor protein kinase WalK	0	1	0	1
Phosphatidylinositol 4-kinase beta	0	4	6	10
P2X purinoceptor 2	0	0	1	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	18	0	0	18
TDP1 protein	49	0	0	49
vitamin D3 receptor isoform VDRA	14	0	0	14
DNA polymerase kappa isoform 1	13	0	0	13
histone acetyltransferase KAT2A isoform 1	11	0	0	11
Chain A, Beta-lactamase	12	0	0	12
Chain A, Ferritin light chain	20	0	0	20
glp-1 receptor, partial	14	0	0	14
SMAD family member 2	17	0	0	17
SMAD family member 3	17	0	0	17
apical membrane antigen 1, AMA1	6	0	0	6
caspase 7, apoptosis-related cysteine protease	10	0	0	10
estrogen receptor 2 (ER beta)	33	0	0	33
nonstructural protein 1	7	0	0	7
pregnane X nuclear receptor	38	0	0	38
67.9K protein	11	0	0	11
glucocerebrosidase	10	0	0	10
bromodomain adjacent to zinc finger domain 2B	14	0	0	14
caspase-3	10	0	0	10
IDH1	15	0	0	15
thyroid stimulating hormone receptor	21	0	0	21
thyrotropin-releasing hormone receptor	6	0	0	6
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	24	0	0	24
Caspase-7	5	0	0	5
caspase-3	5	0	0	5
ubiquitin-conjugating enzyme E2 N	0	2	0	2
nuclear factor NF-kappa-B p105 subunit isoform 1	2	0	0	2
DNA polymerase iota isoform a (long)	13	0	0	13
urokinase-type plasminogen activator precursor	13	0	0	13
plasminogen precursor	13	0	0	13
urokinase plasminogen activator surface receptor precursor	13	0	0	13
nuclear receptor ROR-gamma isoform 1	18	0	0	18
neuropeptide S receptor isoform A	5	0	0	5
Phospholipase D2	0	1	0	1
Estrogen receptor	0	18	4	24
Aromatase	0	5	0	5
Estrogen-related receptor gamma	0	2	1	3
Phospholipase D1	0	2	0	2
Estrogen receptor beta	0	8	3	11
ATPase family AAA domain-containing protein 5	23	0	0	23
Alanine racemase, biosynthetic	0	0	0	1
5-hydroxytryptamine receptor 1D	0	1	0	5
Glutamate receptor ionotropic, NMDA 1	0	5	1	10
Proton-coupled amino acid transporter 1	0	4	0	4
Adenosine deaminase	0	0	0	1
Carbonic anhydrase 4	0	0	0	4
Botulinum neurotoxin type A	0	1	0	1
Neutrophil cytosol factor 1	0	1	0	1
Nitric oxide synthase, endothelial	0	2	0	2
Nitric oxide synthase, brain	0	3	0	3
Nitric oxide synthase, brain	0	1	0	1
Nitric oxide synthase, inducible	0	2	0	2
Kappa-type opioid receptor	0	0	1	2
Mu-type opioid receptor	0	3	1	4
Tyrosine-protein kinase	0	0	1	1
Luciferase	15	0	0	15
interleukin 8	7	0	0	7
thioredoxin reductase	20	0	0	20
cytochrome P450 family 3 subfamily A polypeptide 4	37	0	0	37
G	30	0	0	30
histone deacetylase 9 isoform 3	4	0	0	4
Interferon beta	38	0	0	38
HLA class I histocompatibility antigen, B alpha chain	30	0	0	30
Nicotinate phosphoribosyltransferase	0	3	0	3
Inositol hexakisphosphate kinase 1	30	0	0	30
cytochrome P450 2C9, partial	30	0	0	30
ORF73	0	0	1	1
Beta-lactamase	0	1	0	2
Beta-lactamase	0	1	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase	0	0	0	1
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	4	0	0	4
DNA polymerase eta isoform 1	2	0	0	2
Beta-lactamase SHV-1	0	1	0	2
Beta-lactamase SHV-1	0	2	0	3
Beta-lactamase	0	1	0	2
Solute carrier family 15 member 1	0	2	0	2
Solute carrier family 15 member 1	0	1	0	1
B2 metallo-beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	1	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase	0	1	0	2
Solute carrier family 15 member 2	0	1	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase	0	0	0	1
Chain A, Coagulation factor X (EC 3.4.21.6) (Stuart factor) (Stuart-Prower factor)	0	1	0	1
Coagulation factor X	0	1	0	1
Prothrombin	0	4	0	4
Coagulation factor X	0	5	0	5
Trypsin-1	0	2	0	2
Trypsin-2	0	2	0	2
Trypsin-3	0	2	0	2
Spike glycoprotein	37	0	1	38
Chain A, Hyaluronidase, phage associated	0	1	0	1
thioredoxin glutathione reductase	8	0	0	8
nuclear factor erythroid 2-related factor 2 isoform 2	12	0	0	13
lethal(3)malignant brain tumor-like protein 1 isoform I	1	0	0	1
lethal factor (plasmid)	13	0	0	13
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	2	0	3
Urease	0	2	0	2
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	1	0	1
Alpha-2B adrenergic receptor	0	13	3	17
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
cytochrome P450 2C19 precursor	11	0	0	11
Metabotropic glutamate receptor 6	0	0	1	1
Excitatory amino acid transporter 4	0	1	0	1
Glutamate transporter homolog	0	0	1	1
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	1	0	1
Excitatory amino acid transporter 1	0	1	0	1
Excitatory amino acid transporter 2	0	1	0	1
Excitatory amino acid transporter 3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	4	1	9
Glutamate receptor ionotropic, NMDA 2B	0	4	1	9
Glutamate receptor ionotropic, NMDA 2C	0	4	1	9
Metabotropic glutamate receptor 1	0	0	1	1
Metabotropic glutamate receptor 2	0	0	1	1
Carbonic anhydrase-like protein, putative	0	0	0	5
Glutamate receptor ionotropic, NMDA 2D	0	4	1	9
Glutamate receptor ionotropic, NMDA 3B	0	4	1	9
Glutamate receptor ionotropic, NMDA 3A	0	4	1	9
Chain A, Phospholipase A2 isoform 3	0	0	1	1
Chain A, HADH2 protein	12	0	0	12
Chain B, HADH2 protein	12	0	0	12
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
hypothetical protein, conserved	4	0	0	4
cytochrome P450 2D6	30	0	0	30
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	7	0	0	7
Prostaglandin-H2 D-isomerase	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Epidermal growth factor receptor	0	8	8	16
Fatty acid-binding protein, liver	0	2	0	2
Integrin beta-3	6	1	0	7
Myeloperoxidase	0	3	0	3
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Integrin alpha-IIb	6	1	0	7
Glutathione hydrolase 1 proenzyme	0	1	0	1
Adenosine receptor A1	0	3	0	7
Adenosine receptor A2a	0	5	1	11
Substance-P receptor	0	4	0	4
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Ras-related protein Rab-2A	0	0	1	1
Prostaglandin G/H synthase 2	0	2	0	2
Rho-associated protein kinase 2	0	1	0	1
Solute carrier family 22 member 20	0	3	0	3
Solute carrier family 22 member 6	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	12	1	13
Sigma non-opioid intracellular receptor 1	0	1	1	2
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	2	0	2
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	2	0	2
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	2	0	2
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	2	0	2
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	2	0	2
Leukotriene C4 synthase	0	0	5	5
PPM1D protein	13	0	0	13
tyrosine-protein kinase Yes	6	0	0	6
Bone morphogenetic protein receptor type-1B	0	0	8	8
Cell division cycle 7-related protein kinase	0	0	6	6
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	0	3	6	9
Serine/threonine-protein kinase PLK4	0	4	8	12
Serine/threonine-protein kinase 25	0	0	5	5
ATP-dependent RNA helicase DDX3X	0	0	8	8
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	0	0	6	6
Pyridoxal kinase	0	0	8	8
Citron Rho-interacting kinase	0	0	8	8
Serine/threonine-protein kinase RIO3	0	0	5	5
Dual specificity mitogen-activated protein kinase kinase 7	0	0	5	5
Serine/threonine-protein kinase Chk1	0	2	8	10
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	5	6
Peripheral plasma membrane protein CASK	0	0	5	5
Aurora kinase A	0	2	8	10
Cyclin-G-associated kinase	0	0	8	8
Serine/threonine-protein kinase DCLK1	0	0	5	5
Inhibitor of nuclear factor kappa-B kinase subunit alpha	0	0	5	5
Muscle, skeletal receptor tyrosine-protein kinase	0	0	5	5
Ephrin type-B receptor 6	0	0	7	7
Peroxisomal acyl-coenzyme A oxidase 3	0	0	8	8
Mitogen-activated protein kinase 13	0	0	5	5
3-phosphoinositide-dependent protein kinase 1	0	0	5	5
Mitogen-activated protein kinase kinase kinase 13	0	0	5	5
Death-associated protein kinase 3	0	0	5	5
Receptor-interacting serine/threonine-protein kinase 2	0	1	8	9
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	8	8
NUAK family SNF1-like kinase 1	0	1	5	6
Dynamin-like 120 kDa protein, mitochondrial	0	0	8	8
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	0	0	5	5
Tyrosine-protein kinase JAK2	0	0	7	7
Eukaryotic translation initiation factor 5B	0	0	5	5
Rho-associated protein kinase 2	0	0	8	8
Serine/threonine-protein kinase ULK1	0	0	8	8
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	8	8
Ribosomal protein S6 kinase alpha-5	0	0	8	8
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	8	8
Ribosomal protein S6 kinase alpha-4	0	0	8	8
Serine/threonine-protein kinase 16	0	0	8	8
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	0	0	5	5
Serine/threonine-protein kinase PAK 3	0	0	5	5
Cyclin-dependent kinase-like 5	0	0	7	7
Serine/threonine-protein kinase 17B	0	0	5	5
Serine/threonine-protein kinase 10	0	0	8	8
Serine/threonine-protein kinase D3	0	1	9	10
Cyclin-dependent kinase 14	0	0	5	5
Structural maintenance of chromosomes protein 2	0	0	8	8
Mitogen-activated protein kinase kinase kinase 6	0	0	8	8
Serine/threonine-protein kinase OSR1	0	0	5	5
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	8	8
Serine/threonine-protein kinase LATS1	0	0	8	8
Serine/threonine-protein kinase PAK 4	0	2	8	10
Serine/threonine-protein kinase Chk2	0	1	5	6
Tyrosine-protein kinase ABL1	0	7	9	17
RAF proto-oncogene serine/threonine-protein kinase	0	3	5	8
Receptor tyrosine-protein kinase erbB-2	0	4	5	9
High affinity nerve growth factor receptor	0	0	7	7
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	6	6
ADP/ATP translocase 2	0	0	8	8
Protein kinase C beta type	0	2	9	11
Insulin receptor	0	3	8	11
Tyrosine-protein kinase Lck	0	4	8	12
Tyrosine-protein kinase Fyn	0	2	8	10
Cyclin-dependent kinase 1	0	3	8	11
Glycogen phosphorylase, liver form	0	0	8	8
Tyrosine-protein kinase Fes/Fps	0	0	8	8
Macrophage colony-stimulating factor 1 receptor	0	3	5	8
Adenine phosphoribosyltransferase	0	0	6	6
Tyrosine-protein kinase Yes	0	0	8	8
Tyrosine-protein kinase Lyn	0	1	8	9
Proto-oncogene tyrosine-protein kinase receptor Ret	0	3	8	11
Insulin-like growth factor 1 receptor	0	1	8	9
Signal recognition particle receptor subunit alpha	0	0	7	7
Cytochrome c1, heme protein, mitochondrial	0	0	8	8
Hepatocyte growth factor receptor	0	2	7	9
Tyrosine-protein kinase HCK	0	2	8	10
Proto-oncogene tyrosine-protein kinase ROS	0	0	5	5
Platelet-derived growth factor receptor beta	0	6	8	14
Tyrosine-protein kinase Fgr	0	0	7	7
Wee1-like protein kinase 2	0	0	5	5
Uncharacterized serine/threonine-protein kinase SBK3	0	0	5	5
Serine/threonine-protein kinase A-Raf	0	1	7	8
Mast/stem cell growth factor receptor Kit	0	6	5	11
Glycogen phosphorylase, brain form	0	1	8	9
Breakpoint cluster region protein	0	2	9	12
Serine/threonine-protein kinase pim-1	0	0	8	8
Fibroblast growth factor receptor 1	0	5	8	13
DNA topoisomerase 2-alpha	0	0	7	7
Cyclin-dependent kinase 4	0	3	8	11
ADP/ATP translocase 3	0	0	8	8
Inosine-5'-monophosphate dehydrogenase 2	0	0	8	8
Proto-oncogene tyrosine-protein kinase Src	0	4	8	12
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	8	8
Insulin receptor-related protein	0	0	5	5
Serine/threonine-protein kinase B-raf	0	3	9	12
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	8	8
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	2	8	10
Platelet-derived growth factor receptor alpha	0	5	5	10
Tyrosine-protein kinase Fer	0	0	8	8
Protein kinase C alpha type	0	3	9	12
cAMP-dependent protein kinase catalytic subunit alpha	0	1	8	9
Vascular endothelial growth factor receptor 1	0	6	5	11
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	8	8
Interferon-induced, double-stranded RNA-activated protein kinase	0	0	5	5
Casein kinase II subunit alpha'	0	0	8	8
Ras-related protein Rab-6A	0	0	7	7
Serine/threonine-protein kinase MAK	0	0	5	5
Cyclin-dependent kinase 11B	0	0	5	5
Ephrin type-A receptor 1	0	0	8	8
Fibroblast growth factor receptor 2	0	2	5	7
Receptor tyrosine-protein kinase erbB-3	0	0	5	5
Multifunctional protein ADE2	0	0	8	8
Fibroblast growth factor receptor 4	0	1	5	6
Fibroblast growth factor receptor 3	0	1	5	6
cAMP-dependent protein kinase catalytic subunit gamma	0	0	7	7
cAMP-dependent protein kinase catalytic subunit beta	0	0	8	8
Ferrochelatase, mitochondrial	0	0	8	8
Ribosomal protein S6 kinase beta-1	0	0	8	8
Tyrosine-protein kinase JAK1	0	0	8	8
Protein kinase C eta type	0	1	6	7
Cyclin-dependent kinase 2	0	4	8	12
Beta-adrenergic receptor kinase 1	0	1	9	10
Probable ATP-dependent RNA helicase DDX6	0	0	8	8
Activin receptor type-2A	0	0	5	5
Mitogen-activated protein kinase 3	0	1	8	9
MAP/microtubule affinity-regulating kinase 3	0	0	8	8
Deoxycytidine kinase	0	0	8	8
Mitogen-activated protein kinase 1	0	2	8	10
Ephrin type-A receptor 2	0	0	8	8
Ephrin type-A receptor 3	0	0	5	5
Ephrin type-A receptor 8	0	0	5	5
Ephrin type-B receptor 2	0	0	8	8
Leukocyte tyrosine kinase receptor	0	0	5	5
Non-receptor tyrosine-protein kinase TYK2	0	0	8	8
UMP-CMP kinase	0	0	4	4
Phosphatidylethanolamine-binding protein 1	0	0	6	6
Wee1-like protein kinase	0	0	8	8
Heme oxygenase 2	0	0	8	8
Tyrosine-protein kinase receptor UFO	0	1	5	6
Mitogen-activated protein kinase 4	0	0	5	5
S-adenosylmethionine synthase isoform type-2	0	0	7	7
DnaJ homolog subfamily A member 1	0	0	8	8
RAC-alpha serine/threonine-protein kinase	0	3	8	11
RAC-beta serine/threonine-protein kinase	0	0	8	8
G protein-coupled receptor kinase 4	0	0	5	5
Dual specificity protein kinase TTK	0	0	8	8
DNA replication licensing factor MCM4	0	0	8	8
Myosin-10	0	0	7	7
Tyrosine-protein kinase receptor Tie-1	0	0	5	5
Vascular endothelial growth factor receptor 3	0	6	5	11
Vascular endothelial growth factor receptor 2	0	9	6	16
Dual specificity mitogen-activated protein kinase kinase 2	0	0	8	8
Receptor-type tyrosine-protein kinase FLT3	0	4	8	13
Bone morphogenetic protein receptor type-1A	0	0	8	8
Activin receptor type-1B	0	0	8	8
TGF-beta receptor type-1	0	0	8	8
Serine/threonine-protein kinase receptor R3	0	0	6	6
TGF-beta receptor type-2	0	0	7	7
Electron transfer flavoprotein subunit beta	0	0	6	6
Tyrosine-protein kinase CSK	0	1	8	9
Glycine--tRNA ligase	0	0	8	8
Protein kinase C iota type	0	1	9	10
Exosome RNA helicase MTR4	0	0	8	8
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	4	7	11
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	3	6	9
Serine/threonine-protein kinase mTOR	0	8	8	16
Megakaryocyte-associated tyrosine-protein kinase	0	0	5	5
Tyrosine-protein kinase Tec	0	0	8	8
Tyrosine-protein kinase TXK	0	0	5	5
Tyrosine-protein kinase ABL2	0	1	8	9
Tyrosine-protein kinase FRK	0	0	8	8
G protein-coupled receptor kinase 6	0	0	7	7
Tyrosine-protein kinase ZAP-70	0	0	5	5
Tyrosine-protein kinase SYK	0	1	8	9
26S proteasome regulatory subunit 6B	0	0	8	8
Mitogen-activated protein kinase 8	0	0	8	8
Mitogen-activated protein kinase 9	0	0	8	8
Dual specificity mitogen-activated protein kinase kinase 4	0	1	5	6
Dual specificity mitogen-activated protein kinase kinase 3	0	0	8	8
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	8	8
Casein kinase I isoform alpha	0	2	8	10
Casein kinase I isoform delta	0	0	8	8
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	4	6	10
MAP kinase-activated protein kinase 2	0	0	8	8
Cyclin-dependent kinase 8	0	1	5	6
Elongation factor Tu, mitochondrial	0	0	8	8
Choline-phosphate cytidylyltransferase A	0	0	5	5
Cysteine--tRNA ligase, cytoplasmic	0	0	6	6
Casein kinase I isoform epsilon	0	0	8	8
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	8	8
Dual specificity protein kinase CLK1	0	0	7	7
Dual specificity protein kinase CLK2	0	0	8	8
Dual specificity protein kinase CLK3	0	0	7	7
Glycogen synthase kinase-3 alpha	0	0	8	8
Glycogen synthase kinase-3 beta	0	1	8	9
Cyclin-dependent kinase 7	0	0	8	8
Cyclin-dependent kinase 9	0	0	8	8
Ras-related protein Rab-27A	0	0	8	8
Tyrosine-protein kinase Blk	0	0	5	5
Interleukin-1 receptor-associated kinase 1	0	0	8	8
Ribosomal protein S6 kinase alpha-3	0	1	8	9
Cytoplasmic tyrosine-protein kinase BMX	0	1	5	6
cAMP-dependent protein kinase catalytic subunit PRKX	0	0	5	5
Serine/threonine-protein kinase Nek2	0	1	8	9
Serine/threonine-protein kinase Nek3	0	0	8	8
Serine/threonine-protein kinase Nek4	0	0	5	5
Tyrosine-protein kinase JAK3	0	0	5	5
Dual specificity mitogen-activated protein kinase kinase 6	0	0	8	8
Serine/threonine-protein kinase PLK1	0	6	7	13
Death-associated protein kinase 1	0	1	5	6
LIM domain kinase 1	0	0	8	8
LIM domain kinase 2	0	0	8	8
Mitogen-activated protein kinase 12	0	0	5	5
Mitogen-activated protein kinase 10	0	2	8	10
Tyrosine--tRNA ligase, cytoplasmic	0	0	7	7
5'-AMP-activated protein kinase subunit gamma-1	0	0	8	9
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	1	5	7
Ephrin type-B receptor 3	0	0	8	8
Ephrin type-A receptor 5	0	0	8	8
Ephrin type-B receptor 4	0	2	8	10
Ephrin type-B receptor 1	0	0	5	5
Ephrin type-A receptor 4	0	0	8	8
Adenylate kinase 2, mitochondrial	0	0	8	8
Adenosine kinase	0	0	8	8
Hormonally up-regulated neu tumor-associated kinase	0	0	5	5
Serine/threonine-protein kinase SIK1	0	0	5	5
Receptor-interacting serine/threonine-protein kinase 4	0	0	5	5
Ras-related protein Rab-10	0	0	8	8
Cell division control protein 2 homolog	0	0	5	5
Actin-related protein 3	0	0	8	8
Actin-related protein 2	0	0	8	8
Calcium-dependent protein kinase 1	0	0	5	5
GTP-binding nuclear protein Ran	0	0	8	8
Casein kinase II subunit alpha	0	0	5	5
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	0	0	5	5
SRSF protein kinase 2	0	0	5	5
Casein kinase I isoform gamma-2	0	0	7	7
Mitogen-activated protein kinase kinase kinase 9	0	0	5	5
Serine/threonine-protein kinase PknB	0	0	5	5
Cyclin-dependent kinase 3	0	0	7	7
Cyclin-dependent kinase-like 1	0	0	5	5
Cyclin-dependent kinase 6	0	1	8	9
Cyclin-dependent-like kinase 5	0	0	8	8
Cyclin-dependent kinase 16	0	0	8	8
Cyclin-dependent kinase 17	0	0	7	7
ATP-dependent 6-phosphofructokinase, platelet type	0	0	8	8
Protein kinase C epsilon type	0	2	6	8
Dual specificity mitogen-activated protein kinase kinase 1	0	1	8	9
Angiopoietin-1 receptor	0	2	5	7
Mitogen-activated protein kinase kinase kinase 10	0	0	5	5
DNA topoisomerase 2-beta	0	0	8	8
Protein kinase C theta type	0	1	9	10
Activin receptor type-1	0	0	8	8
Macrophage-stimulating protein receptor	0	0	8	8
Focal adhesion kinase 1	0	1	8	9
Protein kinase C zeta type	0	1	7	8
Protein kinase C delta type	0	2	9	11
Tyrosine-protein kinase BTK	0	0	8	8
Tyrosine-protein kinase receptor TYRO3	0	0	5	5
Cyclin-dependent kinase 18	0	0	6	6
Activated CDC42 kinase 1	0	0	8	8
Epithelial discoidin domain-containing receptor 1	0	0	8	8
Tyrosine-protein kinase ITK/TSK	0	0	5	5
Myotonin-protein kinase	0	0	5	5
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	8	8
Mitogen-activated protein kinase kinase kinase 12	0	0	5	5
Tyrosine-protein kinase Mer	0	1	6	7
Serine/threonine-protein kinase 4	0	0	8	8
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	1	8	10
Serine/threonine-protein kinase PAK 1	0	0	5	5
Dual specificity mitogen-activated protein kinase kinase 5	0	0	8	8
Mitogen-activated protein kinase 7	0	0	7	7
Serine/threonine-protein kinase PAK 2	0	0	8	8
Serine/threonine-protein kinase 3	0	0	8	8
Mitogen-activated protein kinase kinase kinase 1	0	0	8	8
cGMP-dependent protein kinase 2	0	0	5	5
Integrin-linked protein kinase	0	0	7	7
Rho-associated protein kinase 1	0	0	8	8
Non-receptor tyrosine-protein kinase TNK1	0	0	8	8
Serine/threonine-protein kinase PRP4 homolog	0	0	5	5
Receptor-interacting serine/threonine-protein kinase 1	0	2	5	7
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	0	5	5
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	8	8
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	8	8
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	8	8
Activin receptor type-2B	0	0	8	8
Bone morphogenetic protein receptor type-2	0	0	8	8
Protein-tyrosine kinase 6	0	0	8	8
cGMP-dependent protein kinase 1	0	0	8	8
Cyclin-dependent kinase 13	0	0	8	8
Calcium/calmodulin-dependent protein kinase type 1	0	0	5	5
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	8	8
Protein-tyrosine kinase 2-beta	0	0	8	8
Maternal embryonic leucine zipper kinase	0	2	8	10
Structural maintenance of chromosomes protein 1A	0	0	8	8
Chromodomain-helicase-DNA-binding protein 4	0	0	8	8
Peroxisomal acyl-coenzyme A oxidase 1	0	0	8	8
Serine/threonine-protein kinase D1	0	1	6	7
Serine/threonine-protein kinase 38	0	0	6	6
Receptor tyrosine-protein kinase erbB-4	0	0	5	5
Ribosomal protein S6 kinase alpha-2	0	0	5	5
Ephrin type-A receptor 7	0	0	7	7
Delta(24)-sterol reductase	0	0	8	8
Ribosomal protein S6 kinase alpha-1	0	1	8	9
Dual specificity testis-specific protein kinase 1	0	0	8	8
Myosin light chain kinase, smooth muscle	0	1	8	9
Mitogen-activated protein kinase 11	0	0	8	8
Serine/threonine-protein kinase STK11	0	0	8	8
Rhodopsin kinase GRK1	0	1	5	6
NT-3 growth factor receptor	0	0	5	5
Serine/threonine-protein kinase N1	0	0	8	8
Serine/threonine-protein kinase N2	0	0	8	8
Mitogen-activated protein kinase 14	0	3	8	11
Calcium/calmodulin-dependent protein kinase type IV	0	0	8	8
Mitogen-activated protein kinase kinase kinase 11	0	0	8	8
BDNF/NT-3 growth factors receptor	0	0	5	5
Mitogen-activated protein kinase 6	0	0	5	5
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	0	0	5	5
Discoidin domain-containing receptor 2	0	2	8	10
AP2-associated protein kinase 1	0	1	8	9
Myosin light chain kinase 3	0	0	7	7
Serine/threonine-protein kinase SBK1	0	0	5	5
Mitogen-activated protein kinase kinase kinase 19	0	0	5	5
Putative heat shock protein HSP 90-beta 2	0	0	8	8
Serine/threonine-protein kinase TNNI3K	0	1	5	6
Leucine-rich repeat serine/threonine-protein kinase 2	0	1	5	6
Serine/threonine-protein kinase MRCK alpha	0	0	8	8
Serine/threonine-protein kinase MRCK gamma	0	0	7	7
Acyl-CoA dehydrogenase family member 10	0	0	7	7
Serine/threonine-protein kinase Nek5	0	0	5	5
Serine/threonine-protein kinase N3	0	0	7	7
Serine/threonine-protein kinase ULK3	0	0	8	8
Dual serine/threonine and tyrosine protein kinase	0	0	5	5
Mitogen-activated protein kinase kinase kinase 15	0	0	5	5
Uncharacterized protein FLJ45252	0	0	8	8
Acyl-CoA dehydrogenase family member 11	0	0	8	8
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	7	7
Serine/threonine-protein kinase MARK2	0	0	8	8
ATP-dependent RNA helicase DHX30	0	0	7	7
Serine/threonine-protein kinase TAO1	0	0	8	8
STE20-related kinase adapter protein alpha	0	0	8	8
Myosin-14	0	0	8	8
AarF domain-containing protein kinase 1	0	0	8	8
Serine/threonine-protein kinase tousled-like 2	0	0	5	5
Serine/threonine-protein kinase 32C	0	0	5	5
Serine/threonine-protein kinase pim-3	0	0	5	5
ATP-dependent RNA helicase DDX42	0	0	6	6
Serine/threonine-protein kinase VRK2	0	0	5	5
Myosin light chain kinase family member 4	0	0	5	5
Homeodomain-interacting protein kinase 1	0	1	5	6
Calcium/calmodulin-dependent protein kinase type 1D	0	0	5	5
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	8	8
Cyclin-dependent kinase-like 3	0	0	5	5
MAP kinase-activated protein kinase 5	0	0	7	7
Serine/threonine-protein kinase BRSK2	0	0	5	5
Serine/threonine-protein kinase NIM1	0	0	5	5
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	0	0	2	2
Serine/threonine-protein kinase ULK2	0	0	5	5
Misshapen-like kinase 1	0	0	6	6
Serine/threonine-protein kinase DCLK2	0	0	5	5
Calcium/calmodulin-dependent protein kinase kinase 1	0	0	5	5
Casein kinase I isoform alpha-like	0	0	5	5
Homeodomain-interacting protein kinase 4	0	1	5	6
Myosin-IIIa	0	0	5	5
Ankyrin repeat and protein kinase domain-containing protein 1	0	0	5	5
Serine/threonine-protein kinase Nek11	0	0	5	5
Atypical kinase COQ8A, mitochondrial	0	0	8	8
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	8	8
Mitogen-activated protein kinase 15	0	0	8	8
Serine/threonine-protein kinase Nek9	0	0	8	8
Serine/threonine-protein kinase BRSK1	0	0	5	5
Serine/threonine-protein kinase 35	0	0	5	5
Serine/threonine-protein kinase Nek7	0	0	6	6
Rhodopsin kinase GRK7	0	0	5	5
Serine/threonine-protein kinase 32A	0	0	5	5
Myosin-IIIb	0	0	5	5
ATP-dependent RNA helicase DDX1	0	0	8	8
Dual specificity tyrosine-phosphorylation-regulated kinase 2	0	0	5	5
Cyclin-dependent kinase-like 2	0	0	5	5
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	8	8
Serine/threonine-protein kinase Sgk3	0	0	5	5
Atypical kinase COQ8B, mitochondrial	0	0	5	5
Aurora kinase B	0	1	8	9
MAP/microtubule affinity-regulating kinase 4	0	0	8	8
Calcium/calmodulin-dependent protein kinase type 1G	0	0	6	6
Serine/threonine-protein kinase Nek1	0	0	8	8
Cyclin-dependent kinase 15	0	0	5	5
PAS domain-containing serine/threonine-protein kinase	0	0	7	7
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	8	8
EKC/KEOPS complex subunit TP53RK	0	0	8	8
SRSF protein kinase 1	0	0	5	5
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	8	8
Mitogen-activated protein kinase kinase kinase 5	0	0	8	8
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	0	0	5	5
Mitogen-activated protein kinase kinase kinase 3	0	0	8	8
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	8	8
Serine/threonine-protein kinase RIO1	0	0	5	5
MAP kinase-interacting serine/threonine-protein kinase 1	0	0	5	5
Serine/threonine-protein kinase RIO2	0	0	5	5
Cyclin-dependent kinase 19	0	1	5	6
Transient receptor potential cation channel subfamily M member 6	0	0	5	5
Testis-specific serine/threonine-protein kinase 1	0	0	5	5
Serine/threonine-protein kinase 33	0	0	5	5
Nucleolar GTP-binding protein 1	0	0	8	8
Serine/threonine-protein kinase D2	0	0	8	8
Serine/threonine-protein kinase DCLK3	0	0	5	5
NUAK family SNF1-like kinase 2	0	0	7	7
RNA cytidine acetyltransferase	0	0	8	8
Serine/threonine-protein kinase SIK2	0	0	8	8
Myosin light chain kinase 2, skeletal/cardiac muscle	0	0	5	5
STE20-like serine/threonine-protein kinase	0	0	8	8
Serine/threonine-protein kinase TAO3	0	0	8	8
Homeodomain-interacting protein kinase 2	0	1	5	6
Tyrosine-protein kinase Srms	0	0	5	5
Homeodomain-interacting protein kinase 3	0	1	5	6
Serine/threonine-protein kinase PLK3	0	4	5	9
dCTP pyrophosphatase 1	0	0	8	8
Dual specificity protein kinase CLK4	0	0	7	7
MAP kinase-interacting serine/threonine-protein kinase 2	0	1	5	6
Serine/threonine-protein kinase Nek6	0	0	5	5
Casein kinase I isoform gamma-1	0	0	8	8
Serine/threonine-protein kinase PAK 6	0	1	5	6
SNF-related serine/threonine-protein kinase	0	0	5	5
Serine/threonine-protein kinase LATS2	0	0	5	5
Serine/threonine-protein kinase 36	0	0	5	5
Phenylalanine--tRNA ligase beta subunit	0	0	8	8
BMP-2-inducible protein kinase	0	0	8	8
Obg-like ATPase 1	0	0	7	7
Midasin	0	0	8	8
Interleukin-1 receptor-associated kinase 4	0	0	8	8
Serine/threonine-protein kinase 32B	0	0	5	5
Mitogen-activated protein kinase kinase kinase 20	0	0	8	8
Cyclin-dependent kinase 12	0	0	8	8
Serine/threonine-protein kinase PLK2	0	4	5	9
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	7	7
Serine/threonine-protein kinase MARK1	0	0	5	5
Serine/threonine-protein kinase pim-2	0	0	5	5
Serine/threonine-protein kinase PAK 5	0	1	5	6
Serine/threonine-protein kinase 26	0	0	8	8
eIF-2-alpha kinase GCN2	0	0	5	5
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	7	7
Serine/threonine-protein kinase NLK	0	0	8	8
Serine/threonine-protein kinase 17A	0	0	5	5
STE20/SPS1-related proline-alanine-rich protein kinase	0	0	5	5
Ephrin type-A receptor 6	0	0	5	5
5'-AMP-activated protein kinase subunit gamma-2	0	0	8	9
Serine/threonine-protein kinase TBK1	0	2	8	10
Septin-9	0	0	8	8
Death-associated protein kinase 2	0	0	5	5
Ribosomal protein S6 kinase alpha-6	0	0	8	8
TRAF2 and NCK-interacting protein kinase	0	0	8	8
Serine/threonine-protein kinase tousled-like 1	0	0	5	5
Serine/threonine-protein kinase TAO2	0	0	8	8
Long-chain-fatty-acid--CoA ligase 5	0	0	6	6
ALK tyrosine kinase receptor	0	1	5	6
SRSF protein kinase 3	0	0	5	5
Serine/threonine-protein kinase ICK	0	0	7	7
Cyclin-dependent kinase 11A	0	0	5	5
Aurora kinase C	0	0	5	5
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	0	5	5
RAC-gamma serine/threonine-protein kinase	0	0	8	8
Serine/threonine-protein kinase 38-like	0	0	6	6
Microtubule-associated serine/threonine-protein kinase 1	0	0	5	5
Serine/threonine-protein kinase SIK3	0	0	8	8
Mitogen-activated protein kinase kinase kinase 2	0	0	8	8
Thyroid hormone receptor-associated protein 3	0	0	6	6
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	6	6
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	8	8
Receptor-interacting serine/threonine-protein kinase 3	0	1	8	9
Serine/threonine-protein kinase MRCK beta	0	0	8	8
Interleukin-1 receptor-associated kinase 3	0	0	8	8
Serine/threonine-protein kinase 24	0	0	7	7
Casein kinase I isoform gamma-3	0	0	8	8
Mitogen-activated protein kinase kinase kinase 4	0	0	8	8
Replicase polyprotein 1ab	0	2	1	3
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Chain A, D-MALTODEXTRIN BINDING PROTEIN	0	0	1	1
Chain A, Limit Dextrinase	0	0	1	1
Chain A, Solute-binding protein	0	0	1	1
Chain A, Solute-binding protein	0	0	1	1
Chain B, SusD	0	0	1	1
Chain A, SusD	0	0	1	1
Chain A, SusD	0	0	1	1
Chain A, Alpha-hemolysin	0	0	1	1
Chain B, Alpha-hemolysin	0	0	1	1
Chain C, Alpha-hemolysin	0	0	1	1
Chain D, Alpha-hemolysin	0	0	1	1
Chain E, Alpha-hemolysin	0	0	1	1
Chain F, Alpha-hemolysin	0	0	1	1
Chain G, Alpha-hemolysin	0	0	1	1
potassium voltage-gated channel subfamily H member 2 isoform d	14	0	0	14
Chain A, Putative fructose-1,6-bisphosphate aldolase	7	0	0	7
Chain A, Cruzipain	5	0	0	5
caspase-1 isoform alpha precursor	2	0	0	2
Caspase-7	2	0	0	2
Solute carrier organic anion transporter family member 1B3	0	4	0	5
Solute carrier organic anion transporter family member 1B1	0	7	0	8
Nuclear receptor subfamily 1 group I member 2	0	0	4	4
Endothelin receptor type B	1	3	1	5
Endothelin receptor type B	0	4	1	5
Endothelin-1 receptor	0	4	1	5
Endothelin-1 receptor	1	2	2	5
Endothelin receptor type B	0	0	1	1
Deoxyhypusine synthase	0	1	0	1
Sodium/bile acid cotransporter	0	3	0	3
Endothelin-1 receptor	0	1	0	1
Angiotensin-converting enzyme	0	0	0	1
B2 bradykinin receptor	0	1	0	1
B2 bradykinin receptor	0	4	1	7
B1 bradykinin receptor	0	1	0	1
Olfactory receptor 51E2	0	0	3	3
nuclear receptor subfamily 1, group I, member 2	7	0	0	7
cellular tumor antigen p53 isoform a	9	0	0	9
Nuclear hormone receptor family member daf-12	0	0	1	1
serine/threonine-protein kinase mTOR isoform 1	6	0	0	6
oxysterols receptor LXR-beta isoform 1	0	0	1	1
Thymidine kinase, cytosolic	0	1	0	1
Thymidine phosphorylase	0	0	0	2
Thymidylate kinase	0	1	0	1
Thymidine kinase	0	0	0	2
Thymidylate kinase	0	2	0	2
Chain A, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	1	0	1
Fumarate hydratase	12	0	0	12
polyprotein	12	0	0	12
Membrane-associated progesterone receptor component 1	0	0	4	4
Cytochrome P450 2C8	0	4	0	4
Cytochrome P450 2B6	0	7	0	7
Nucleoside diphosphate kinase B	0	0	1	1
Phosphatidylinositol 3-kinase regulatory subunit alpha	0	1	0	1
Cytochrome P450 2C19	0	9	0	9
Aldo-keto reductase family 1 member C3	0	2	0	2
DNA-dependent protein kinase catalytic subunit	0	4	1	5
Potassium voltage-gated channel subfamily H member 2	0	19	0	19
Rab-like protein 3	0	0	5	5
Phosphatidylinositol 3-kinase catalytic subunit type 3	0	1	1	2
Phosphoinositide 3-kinase regulatory subunit 5	0	1	0	1
Dual specificity testis-specific protein kinase 2	0	0	4	4
Serine/threonine-protein kinase mTOR	0	2	0	2
Isoleucine--tRNA ligase, mitochondrial	0	0	5	5
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	1	0	1
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	0	3	3
Potassium channel subfamily K member 9	0	1	0	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	3	0	0	3
Matrix metalloproteinase-9	0	1	0	1
Disintegrin and metalloproteinase domain-containing protein 17	3	0	0	3
Chain A, Glycogen Phosphorylase	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Chitinase	0	1	0	1
atrial natriuretic peptide receptor 1 precursor	3	0	0	3
DNA polymerase beta	5	0	0	5
Glycogen phosphorylase, muscle form	0	1	0	1
Renin	0	1	0	1
Cholinesterase	0	2	0	2
Glycogen phosphorylase, liver form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Replicase polyprotein 1ab	0	1	1	2
Adenosine receptor A3	0	10	1	11
Amine oxidase [flavin-containing] A	0	4	0	4
Acetylcholinesterase	0	6	0	6
Amine oxidase [flavin-containing] B	0	4	0	4
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	3	0	3
Adenosine receptor A3	0	1	0	1
Adenosine receptor A2a	0	10	2	13
Adenosine receptor A2b	0	1	0	2
Adenosine receptor A2b	0	2	1	4
Adenosine receptor A1	0	7	1	10
Vasopressin V2 receptor	0	0	0	1
Adenosine receptor A2a	0	1	0	1
Adenosine receptor A1	0	2	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Adenylate cyclase type 1	0	0	0	1
Chitotriosidase-1	0	1	0	1
Serine-protein kinase ATM	0	1	0	1
Serine/threonine-protein kinase ATR	0	1	3	4
Adenosine receptor A2b	0	1	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	1	2	3
Endochitinase B1	0	1	0	1
Muscarinic acetylcholine receptor	0	0	0	1
Phosphodiesterase	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	9	0	9
Guanine deaminase	0	1	0	1
Lactoperoxidase	0	1	0	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	13	0	0	13
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	9	0	0	9
importin subunit beta-1 isoform 1	5	0	0	5
mitogen-activated protein kinase 1	7	0	0	7
snurportin-1	5	0	0	5
Glucocorticoid receptor	0	20	1	22
Glycine receptor subunit alpha-1	0	20	0	20
Androgen receptor	0	21	0	21
Glycine receptor subunit beta	0	20	0	20
Glycine receptor subunit alpha-2	0	20	0	20
Glycine receptor subunit alpha-3	0	20	0	20
alpha-galactosidase	2	0	0	2
M-phase phosphoprotein 8	9	0	0	9
Solute carrier family 22 member 1	0	1	0	1
Solute carrier family 22 member 2	0	6	0	9
Solute carrier family 22 member 1	0	9	0	13
Solute carrier family 22 member 2	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	3	0	3
ATP-dependent translocase ABCB1	0	3	0	3
ATP-dependent translocase ABCB1	0	12	3	15
Potassium-transporting ATPase alpha chain 1	0	1	0	1
ATP-dependent translocase ABCB1	0	3	0	3
Histamine H2 receptor	0	7	2	9
Histamine H1 receptor	0	1	3	5
Histamine H2 receptor	10	2	2	15
Potassium-transporting ATPase subunit beta	0	1	0	1
Aldehyde oxidase	0	3	0	3
Solute carrier family 22 member 6	0	2	0	3
Solute carrier family 22 member 1	0	6	0	8
Multidrug and toxin extrusion protein 2	0	4	0	4
Solute carrier family 22 member 8	0	3	0	5
Multidrug and toxin extrusion protein 1	0	10	0	10
Histamine H4 receptor	0	4	2	6
Solute carrier family 22 member 11	0	1	0	2
Solute carrier family 22 member 2	0	5	0	6
Solute carrier family 22 member 4	0	1	0	1
Solute carrier family 22 member 8	0	2	0	2
NPC intracellular cholesterol transporter 1 precursor	5	0	0	5
Sodium-dependent noradrenaline transporter	0	3	0	3
5-hydroxytryptamine receptor 4	0	16	0	16
Aldo-keto reductase family 1 member B1	0	17	0	17
Tryptophan 5-hydroxylase 1	0	1	0	1
Angiotensin-converting enzyme	0	10	0	10
Aldo-keto reductase family 1 member B1	0	2	0	2
Aromatase	0	1	0	1
Sodium-dependent noradrenaline transporter	0	16	2	18
Sodium-dependent dopamine transporter	0	3	0	3
Alpha-1D adrenergic receptor	0	10	3	14
5-hydroxytryptamine receptor 2C	0	17	1	18
Histamine H1 receptor	0	8	3	11
5-hydroxytryptamine receptor 2B	0	13	1	14
5-hydroxytryptamine receptor 7	0	3	0	3
Sodium-dependent dopamine transporter	0	11	1	12
Sigma intracellular receptor 2	0	1	0	1
Sodium-dependent serotonin transporter	0	3	0	3
Sodium-dependent dopamine transporter	0	2	0	2
Nuclear receptor subfamily 3 group C member 3	0	10	0	10
Transporter	0	7	1	9
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	2	0	2
Neutrophil elastase	0	2	0	2
Beta-lactamase OXA-1	0	1	0	1
Beta-lactamase TEM	0	2	0	3
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Class D beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Metallo-b-lactamase	0	0	0	1
Beta-lactamase	0	1	0	1
Carbapenem-hydrolyzing beta-lactamase KPC	0	2	0	2
Beta-lactamase class B VIM-2	0	0	0	1
Beta-1 adrenergic receptor	0	1	3	5
Alpha-1B adrenergic receptor	0	0	2	2
cytochrome P450 2D6 isoform 1	9	0	0	9
cytochrome P450 2C9 precursor	5	0	0	5
Membrane primary amine oxidase	0	1	0	1
5-hydroxytryptamine receptor 3A	0	0	1	1
Solute carrier family 22 member 3	0	3	0	4
5-hydroxytryptamine receptor 1A	0	3	1	4
Alpha-2A adrenergic receptor	0	16	5	22
Alpha-1B adrenergic receptor	0	13	1	14
Alpha-1A adrenergic receptor	0	2	2	4
Alpha-2C adrenergic receptor	0	13	4	18
D	0	2	0	2
D(3) dopamine receptor	0	3	0	3
Alpha-2B adrenergic receptor	0	6	2	8
Alpha-2C adrenergic receptor	0	6	2	8
Alpha-2A adrenergic receptor	0	6	2	8
Alpha-1D adrenergic receptor	0	6	1	7
D(1B) dopamine receptor	0	2	0	2
Alpha-2B adrenergic receptor	0	1	0	3
D(4) dopamine receptor	0	2	0	2
Delta-type opioid receptor	0	2	1	3
Alpha-1A adrenergic receptor	0	4	5	10
Alpha-1B adrenergic receptor	0	3	4	8
Alpha-1A adrenergic receptor	0	14	2	16
D(2) dopamine receptor	0	3	0	3
Alpha-2C adrenergic receptor	0	1	0	3
Alpha-2A adrenergic receptor	0	1	0	3
Alpha-2A adrenergic receptor	0	2	0	2
Nischarin	0	2	0	2
Nischarin	0	2	0	2
Liver carboxylesterase 1	0	0	0	1
Rap guanine nucleotide exchange factor 4	3	0	0	3
P2Y purinoceptor 12	0	1	0	1
endonuclease IV	3	0	0	3
peripheral myelin protein 22 isoform 1	8	0	0	8
Sex hormone-binding globulin	0	0	7	7
Corticosteroid-binding globulin	0	2	0	2
Potassium voltage-gated channel subfamily A member 1	0	1	1	2
TAR DNA-binding protein 43	10	0	0	10
huntingtin isoform 2	7	0	0	7
atrial natriuretic peptide receptor 2 precursor	3	0	0	3
chaperonin GroEL	2	0	0	2
Polyunsaturated fatty acid lipoxygenase ALOX15B	7	0	0	7
Muscarinic acetylcholine receptor M2	0	9	1	11
Muscarinic acetylcholine receptor M4	0	10	0	11
Muscarinic acetylcholine receptor M1	0	3	0	3
Muscarinic acetylcholine receptor M3	0	2	0	2
Muscarinic acetylcholine receptor M4	0	3	0	3
Muscarinic acetylcholine receptor M5	0	2	0	2
Muscarinic acetylcholine receptor M5	0	10	0	11
Muscarinic acetylcholine receptor M2	0	2	0	2
Glycogen phosphorylase, muscle form	0	1	0	1
Muscarinic acetylcholine receptor M1	0	9	1	11
D(2) dopamine receptor	0	5	1	6
Muscarinic acetylcholine receptor M3	0	11	1	13
D(1A) dopamine receptor	0	7	1	8
UDP-glucuronosyltransferase 1A4	0	0	0	3
5-hydroxytryptamine receptor 2A	0	15	1	16
5-hydroxytryptamine receptor 2C	0	1	0	1
5-hydroxytryptamine receptor 7	0	3	1	4
D(3) dopamine receptor	0	6	0	6
UDP-glucuronosyltransferase 1A3	0	0	0	1
5-hydroxytryptamine receptor 6	0	9	1	10
D(2) dopamine receptor	0	1	0	1
Histone-lysine N-methyltransferase SETD7	0	2	0	2
Plasminogen	0	3	1	4
Coagulation factor XII	0	2	0	2
Tissue-type plasminogen activator	0	1	0	1
Vitamin K-dependent protein C	0	1	0	1
Serine protease hepsin	0	1	0	1
Rap guanine nucleotide exchange factor 3	3	0	0	3
Beta-3 adrenergic receptor	0	8	3	11
Substance-K receptor	0	4	0	4
Vasopressin V2 receptor	0	1	1	2
Oxytocin receptor	0	0	1	1
Vasopressin V1a receptor	0	2	2	4
Vasopressin V1b receptor	0	1	1	2
Translocator protein	0	1	0	1
Vasopressin V2 receptor	0	1	1	2
NAD	0	1	0	1
NAD	0	1	0	2
ATP phosphoribosyltransferase	0	1	0	1
Proprotein convertase subtilisin/kexin type 7	0	2	0	2
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
Integrase	0	2	0	2
G-protein coupled receptor 35	0	2	2	4
Estrogen receptor 1	0	0	1	1
TPA: protein transporter TIM10	0	1	0	1
beta-2 adrenergic receptor	3	0	0	3
lysosomal alpha-glucosidase preproprotein	8	0	0	8
polyunsaturated fatty acid lipoxygenase ALOX12	2	0	0	2
GTP-binding nuclear protein Ran isoform 1	3	0	0	3
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	3	0	0	3
Neuronal acetylcholine receptor subunit alpha-4	5	2	2	10
Neuronal acetylcholine receptor subunit beta-2	5	2	2	10
Alpha-synuclein	6	1	0	7
Cereblon isoform 4	0	5	0	5
Insulin-like growth factor-binding protein 5	0	0	1	1
Choline O-acetyltransferase	0	1	0	1
Protein cereblon	0	6	2	11
prostaglandin E2 receptor EP2 subtype	1	0	0	1
Solute carrier organic anion transporter family member 1A5	0	0	0	1
Prostaglandin E2 receptor EP3 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	0	1
Prostaglandin E2 receptor EP1 subtype	0	2	3	5
Prostaglandin E2 receptor EP1 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	2	1	3
Prostaglandin F2-alpha receptor	0	0	1	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP3 subtype	0	3	1	4
Prostaglandin E2 receptor EP2 subtype	0	2	3	5
Prostacyclin receptor	0	4	3	7
Solute carrier organic anion transporter family member 2A1	0	1	0	3
Solute carrier family 22 member 7	0	0	0	2
Prostaglandin E2 receptor EP2 subtype	0	1	0	1
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier family 22 member 7	0	0	0	1
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier organic anion transporter family member 1B2	0	0	0	1
Solute carrier family 22 member 7	0	0	0	1
Histamine N-methyltransferase	0	0	0	1
Sodium channel protein type 5 subunit alpha	0	6	0	6
Calcium release-activated calcium channel protein 1	0	1	0	1
Protein orai-2	0	1	0	1
Protein orai-3	0	1	0	1
Histamine H3 receptor	0	1	0	2
Chain A, Breast cancer type 1 susceptibility protein	1	0	0	1
acid sphingomyelinase	4	0	0	4
RGS12	1	0	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
DNA polymerase III, partial	2	0	0	2
isocitrate dehydrogenase 1, partial	2	0	0	2
LANA	0	0	0	1
NPYLR7B	0	0	1	1
serine-protein kinase ATM isoform a	2	0	0	2
guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1	1	0	0	1
serine/threonine-protein kinase PLK1	4	0	0	4
eyes absent homolog 2 isoform a	2	0	0	2
heat shock protein HSP 90-alpha isoform 2	0	1	0	2
histone-lysine N-methyltransferase 2A isoform 2 precursor	6	0	0	6
tumor susceptibility gene 101 protein	1	0	0	1
muscleblind-like protein 1 isoform 1	6	0	0	6
DNA dC->dU-editing enzyme APOBEC-3F isoform a	1	0	0	1
kelch-like ECH-associated protein 1	0	0	0	2
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Multidrug resistance-associated protein 5	0	1	0	1
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta	0	1	0	1
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	1	0	1
3',5'-cyclic-AMP phosphodiesterase	0	1	0	1
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha	0	1	0	1
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	1	0	1
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta	0	1	0	1
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	2	0	2
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	1	0	1
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	0	1	0	1
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	2	0	2
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	1	0	1
Exopolyphosphatase PRUNE1	0	1	0	1
Equilibrative nucleoside transporter 1	0	2	0	2
Single-stranded DNA cytosine deaminase	1	0	0	1
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 7B	0	1	0	1
Phosphodiesterase	0	1	0	1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	1	0	1
Uridine phosphorylase 1	0	0	0	1
Serine/threonine-protein kinase B-raf	0	2	0	2
Motilin receptor	0	0	1	1
low molecular weight phosphotyrosine protein phosphatase isoform c	0	1	0	1
streptokinase A precursor	0	0	3	3
Motilin receptor	0	1	1	2
30S ribosomal protein S6	0	1	1	2
30S ribosomal protein S7	0	1	1	2
50S ribosomal protein L15	0	1	1	2
Albumin	0	3	4	7
60 kDa chaperonin	0	1	0	1
50S ribosomal protein L10	0	1	1	2
50S ribosomal protein L11	0	1	1	2
50S ribosomal protein L7/L12	0	1	1	2
50S ribosomal protein L19	0	1	1	2
50S ribosomal protein L1	0	1	1	2
50S ribosomal protein L20	0	1	1	2
50S ribosomal protein L27	0	1	1	2
50S ribosomal protein L28	0	1	1	2
50S ribosomal protein L29	0	1	1	2
50S ribosomal protein L31	0	1	1	2
50S ribosomal protein L31 type B	0	1	1	2
50S ribosomal protein L32	0	1	1	2
50S ribosomal protein L33	0	1	1	2
50S ribosomal protein L34	0	1	1	2
50S ribosomal protein L35	0	1	1	2
50S ribosomal protein L36	0	1	1	2
30S ribosomal protein S10	0	1	1	2
30S ribosomal protein S11	0	1	1	2
30S ribosomal protein S12	0	1	1	2
30S ribosomal protein S13	0	1	1	2
30S ribosomal protein S16	0	1	1	2
30S ribosomal protein S18	0	1	1	2
30S ribosomal protein S19	0	1	1	2
30S ribosomal protein S20	0	1	1	2
30S ribosomal protein S2	0	1	1	2
30S ribosomal protein S3	0	1	1	2
30S ribosomal protein S4	0	1	1	2
30S ribosomal protein S5	0	1	1	2
30S ribosomal protein S8	0	1	1	2
30S ribosomal protein S9	0	1	1	2
50S ribosomal protein L13	0	1	1	2
50S ribosomal protein L14	0	1	1	2
50S ribosomal protein L16	0	1	1	2
50S ribosomal protein L23	0	1	1	2
30S ribosomal protein S15	0	1	1	2
50S ribosomal protein L17	0	1	1	2
50S ribosomal protein L21	0	1	1	2
50S ribosomal protein L30	0	1	1	2
50S ribosomal protein L6	0	1	1	2
30S ribosomal protein S14	0	1	1	2
30S ribosomal protein S17	0	1	1	2
30S ribosomal protein S1	0	1	1	2
50S ribosomal protein L18	0	1	1	2
60 kDa heat shock protein, mitochondrial	0	2	0	2
Chitinase B	0	1	0	1
Low molecular weight phosphotyrosine protein phosphatase	0	1	0	1
50S ribosomal protein L2	0	1	1	2
50S ribosomal protein L3	0	1	1	2
50S ribosomal protein L24	0	1	1	2
50S ribosomal protein L4	0	1	1	2
50S ribosomal protein L22	0	1	1	2
10 kDa heat shock protein, mitochondrial	0	2	0	2
50S ribosomal protein L5	0	1	1	2
30S ribosomal protein S21	0	1	1	2
50S ribosomal protein L25	0	1	1	2
Thiosulfate sulfurtransferase	0	2	0	2
Lanosterol 14-alpha demethylase	0	2	0	2
50S ribosomal protein L36 2	0	1	1	2
60 kDa chaperonin	0	2	0	2
10 kDa chaperonin	0	2	0	2
UDP-glucuronosyltransferase 2B7	0	0	0	2
Solute carrier organic anion transporter family member 1A1	0	1	0	1
Lanosterol 14-alpha demethylase	0	0	1	1
UDP-glucuronosyltransferase 1A10	0	0	0	1
Vpr	4	0	0	4
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	2	0	2
Sulfotransferase 1A1	0	2	1	4
Nuclear receptor subfamily 1 group I member 3	0	1	0	1
Potassium voltage-gated channel subfamily E member 1	0	3	0	3
Potassium voltage-gated channel subfamily KQT member 1	0	3	0	3
Regulatory-associated protein of mTOR	0	2	0	2
Target of rapamycin complex subunit LST8	0	2	0	2
Potassium voltage-gated channel subfamily D member 3	0	3	0	3
interferon gamma precursor	0	0	0	2
Sodium/nucleoside cotransporter 2	0	1	0	1
Thymidylate synthase	0	3	0	3
Chain A, Uracil Phosphoribosyltransferase	0	1	0	1
Skn7p	0	0	0	1
hemoglobin subunit beta	1	0	0	1
Solute carrier family 22 member 8	0	0	0	1
Amyloid-beta precursor protein	1	2	0	3
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	1
Chain A, Dihydrofolate reductase	0	0	1	1
Thymidylate synthase	0	2	0	2
Dihydrofolate reductase	0	0	1	1
Aldo-keto reductase family 1 member B1	0	3	0	3
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Solute carrier organic anion transporter family member 1A3	0	1	0	1
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Multidrug resistance associated protein	0	0	0	1
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Serum paraoxonase/arylesterase 1	0	1	0	1
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Holo-[acyl-carrier-protein] synthase	0	1	0	1
CDGSH iron-sulfur domain-containing protein 1	0	2	0	2
Chain A, Estrogen receptor 1 (alpha)	0	1	0	1
Chain A, Transthyretin	0	0	1	1
Chain A, Transthyretin	0	0	1	1
BRCA1	1	0	0	1
Neuraminidase	0	3	0	3
Parkin	4	0	0	4
P53	2	0	0	2
Alpha-mannosidase	0	1	0	1
pyruvate kinase	2	0	0	2
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	4	0	0	4
hexokinase-4 isoform 1	1	0	0	1
glucokinase regulatory protein	1	0	0	1
glycogen synthase kinase-3 beta isoform 1	0	0	2	2
ras-related protein Rab-9A	5	0	0	5
pyruvate kinase PKM isoform b	1	0	0	1
Maltase-glucoamylase, intestinal	0	2	0	2
Steroid hormone receptor ERR2	0	1	0	1
Pancreatic triacylglycerol lipase	0	1	0	1
Triosephosphate isomerase	0	1	0	1
Transthyretin	0	1	0	1
Ornithine decarboxylase	1	0	0	1
Androgen receptor	0	1	0	2
Sialidase	0	2	0	2
Solute carrier family 2, facilitated glucose transporter member 1	0	1	0	1
Tyrosinase	0	1	0	1
Steroid hormone receptor ERR1	0	2	0	2
Ornithine decarboxylase	0	1	0	1
Cystic fibrosis transmembrane conductance regulator	0	0	2	2
17-beta-hydroxysteroid dehydrogenase type 1	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 4	0	1	0	1
G2/mitotic-specific cyclin-B1	0	2	0	2
Dipeptidyl peptidase 4	0	1	0	1
Amine oxidase [flavin-containing] A	0	1	0	1
Amine oxidase [flavin-containing] A	0	1	0	1
G1/S-specific cyclin-D1	0	2	0	2
Thromboxane-A synthase	0	3	0	3
Cruzipain	0	2	0	2
DNA (cytosine-5)-methyltransferase 1	0	1	0	1
Dipeptidyl peptidase 4	0	3	0	3
Proteasome subunit beta type-5	0	1	0	1
Cystic fibrosis transmembrane conductance regulator	0	0	1	1
Testosterone 17-beta-dehydrogenase 3	0	1	0	1
17-beta-hydroxysteroid dehydrogenase type 2	0	1	0	1
Acetylcholinesterase	0	1	0	1
Alpha-glucosidase MAL32	0	1	0	1
Signal transducer and activator of transcription 3	0	1	0	1
Quinone oxidoreductase	0	0	0	1
Xanthine dehydrogenase/oxidase	0	3	0	3
Oxysterols receptor LXR-beta	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Xanthine dehydrogenase/oxidase	0	2	0	2
MO15-related protein kinase Pfmrk	0	1	0	1
Oxysterols receptor LXR-alpha	0	1	0	1
Tissue alpha-L-fucosidase	0	1	0	1
Substance-K receptor	0	2	0	2
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)	0	1	0	1
Prenyltransferase homolog	0	0	0	1
Carboxylic ester hydrolase	0	1	0	2
Dipeptidyl peptidase 3	0	1	0	1
DNA (cytosine-5)-methyltransferase 3-like	0	1	0	1
Sialidase-2	0	1	0	1
DNA (cytosine-5)-methyltransferase 3A	0	1	0	1
Glycine receptor subunit alpha-1	0	0	1	1
Sodium- and chloride-dependent glycine transporter 1	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	5	0	5
Serine racemase	0	1	0	1
Sodium- and chloride-dependent glycine transporter 2	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	8	0	9
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Protein (female-specific Histamine Binding Protein 2)	0	0	1	1
aryl hydrocarbon receptor nuclear translocator	0	0	0	1
GALC protein	4	0	0	4
transforming acidic coiled-coil-containing protein 3	0	0	0	1
Plasma kallikrein	0	0	0	4
Macrophage migration inhibitory factor	0	2	0	2
Histamine H1 receptor	0	2	1	3
Metabotropic glutamate receptor 5	0	1	1	2
Carbonic anhydrase	0	1	0	5
Carbonic anhydrase	0	0	0	5
Histamine H3 receptor	0	1	0	1
Histamine N-methyltransferase	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	2	0	2
Carbonic anhydrase	0	0	0	5
Carbonic anhydrase	0	0	0	5
Carbonic anhydrase	0	0	0	5
Carbonic anhydrase	0	0	0	5
Equilibrative nucleoside transporter 4	0	0	0	1
Carbonic anhydrase 13	0	0	0	2
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	0	1
Histamine H3 receptor	0	1	2	3
Chain A, HISTIDINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Histidine-binding periplasmic protein	0	0	1	1
Nrf2	1	0	0	1
luciferase	2	0	0	2
pyruvate kinase PKM isoform a	2	0	0	2
phosphoglycerate kinase	2	0	0	2
Prostacyclin receptor	0	1	1	2
Prostaglandin D2 receptor	0	0	2	2
Chain A, Cell Division Protein Kinase 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, Cell Division Protein Kinase 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, Cell Division Protein Kinase 2	0	1	0	1
DNA repair and recombination protein RadA	0	0	1	1
Indoleamine 2,3-dioxygenase 1	0	1	1	3
Cyclin-A2	0	1	0	1
Cyclin-A1	0	1	0	1
Cytochrome P450 144	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Trans-sialidase	0	0	0	1
Bromodomain-containing protein 4	0	1	0	1
DNA-binding protein Ikaros	0	0	1	4
DNA damage-binding protein 1	0	2	1	3
Zinc finger protein Aiolos	0	0	1	1
Gonadotropin-releasing hormone receptor	0	1	0	1
Gonadotropin-releasing hormone receptor	0	2	0	2
PINK1	2	0	0	2
Large neutral amino acids transporter small subunit 1	0	1	0	1
cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 7	0	0	0	1
Cannabinoid receptor 1	0	2	0	2
Dihydrofolate reductase	0	3	0	3
Chain E, Fibrin beta chain	0	1	0	1
T cell receptor, partial	1	0	0	1
luteinizing hormone receptor	1	0	0	1
integrase, partial	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	2	0	0	2
lens epithelium-derived growth factor p75	0	1	0	1
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	1
TSHR protein	1	0	0	1
Apoptotic peptidase activating factor 1	0	1	0	1
neutrophil cytosol factor 1	0	1	0	1
caspase-9 isoform alpha precursor	0	1	0	1
caspase-3 isoform a preproprotein	0	1	0	1
protein AF-9 isoform a	0	0	0	1
replicative DNA helicase	0	0	0	1
recombinase A	0	0	1	1
POsterior Segregation	0	0	1	1
DNA repair protein RAD52 homolog isoform a	0	0	0	1
Glutathione reductase	0	1	0	1
Glutathione reductase, mitochondrial	0	3	0	4
Glycoprotein hormones alpha chain	1	0	0	1
Dihydrolipoyl dehydrogenase, mitochondrial	0	1	0	2
Microtubule-associated protein tau	0	1	1	2
Thioredoxin reductase 1, cytoplasmic	0	1	0	2
Dihydrolipoyl dehydrogenase	0	1	0	2
Zinc finger protein mex-5	0	0	1	1
Thioredoxin reductase	0	1	0	1
Flavodoxin	0	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	5	0	5
Voltage-dependent L-type calcium channel subunit alpha-1D	0	5	0	5
Voltage-dependent L-type calcium channel subunit alpha-1S	0	5	0	5
Presenilin-1	0	1	0	1
Presenilin-2	0	1	0	1
Gamma-secretase subunit APH-1B	0	1	0	1
Nicastrin	0	1	0	1
Gamma-secretase subunit APH-1A	0	1	0	1
Gamma-secretase subunit PEN-2	0	1	0	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
Atrial natriuretic peptide receptor 1	0	1	0	1
Nitric oxide synthase, endothelial	0	1	0	1
Nitric oxide synthase, inducible	0	1	0	1
Collagenase 3	0	1	0	1
Cholesteryl ester transfer protein	0	1	0	1
D-amino-acid oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 3	0	0	1	1
Nicotinamidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	0	1	1
Hydroxycarboxylic acid receptor 2	0	2	1	3
D-aspartate oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	1	1	2
Chain A, NAD-dependent deacetylase	0	1	0	1
Poly [ADP-ribose] polymerase 2	0	1	0	1
NAD-dependent histone deacetylase SIR2	0	1	0	1
Coagulation factor VII	0	1	0	1
Poly [ADP-ribose] polymerase 1	0	1	0	1
Tissue factor	0	1	0	1
Cytochrome P450 3A5	0	2	0	2
NAD-dependent protein deacetylase HST2	0	1	0	1
Fatty-acid amide hydrolase 1	0	2	0	2
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
NAD(+) hydrolase SARM1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-2	0	2	0	2
NAD-dependent protein deacetylase sirtuin-6	0	1	0	1
NAD-dependent protein deacetylase sirtuin-1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	1	0	1
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
NAD-dependent protein deacetylase	0	1	0	1
5-hydroxytryptamine receptor 3E	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
5-hydroxytryptamine receptor 3B	0	1	0	1
Acetylcholine receptor subunit alpha	0	2	1	3
Acetylcholine receptor subunit alpha	0	2	1	3
Acetylcholine receptor subunit beta	0	2	1	3
Acetylcholine receptor subunit gamma	0	2	1	3
Acetylcholine receptor subunit delta	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-3	0	2	2	5
Acetylcholine receptor subunit gamma	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-4	0	1	0	1
Acetylcholine receptor subunit beta	0	2	1	3
Cytochrome P450 2A6	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-2	0	2	2	5
Neuronal acetylcholine receptor subunit beta-3	0	2	2	5
Neuronal acetylcholine receptor subunit beta-4	0	2	2	5
Translocator protein	0	2	0	2
Neuronal acetylcholine receptor subunit beta-2	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-5	0	2	2	5
Cytochrome P450 2A5	0	1	0	1
Acetylcholine receptor subunit beta-like 2	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-5	0	0	1	1
Neuronal acetylcholine receptor subunit beta-4	0	2	1	3
Muscarinic acetylcholine receptor M4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-3	0	2	1	3
Delta-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	2	2	4
Neuronal acetylcholine receptor subunit alpha-6	0	2	2	5
Neuronal acetylcholine receptor subunit alpha-9	0	2	2	5
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
5-hydroxytryptamine receptor 3A	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	2	0	2
Acetylcholine-binding protein	0	1	1	2
Acetylcholine receptor subunit epsilon	0	0	1	1
Neuronal acetylcholine receptor subunit beta-3	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-7	0	2	2	5
Acetylcholine receptor subunit delta	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	1	2
Cytochrome P450 2A13	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-5	0	2	0	2
Liver carboxylesterase B-1	0	1	0	1
5-hydroxytryptamine receptor 3D	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	2	2
Neuronal acetylcholine receptor subunit beta-3	0	2	0	2
Neuronal acetylcholine receptor subunit beta-4	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-3	0	2	0	2
Soluble acetylcholine receptor	0	1	0	1
5-hydroxytryptamine receptor 3C	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-2	0	2	0	2
Neuronal acetylcholine receptor subunit beta-2	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-10	0	2	2	5
Neuronal acetylcholine receptor subunit alpha-6	0	2	0	2
Integrin beta	0	0	1	1
Glycoprotein IIb	0	0	1	1
tumor necrosis factor	1	0	0	1
perilipin-5	0	1	0	1
perilipin-1	0	1	0	1
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Phospholipase A2, membrane associated	0	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	0	3
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Platelet-activating factor receptor	0	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	1	0	1
C-C chemokine receptor type 2	0	2	0	2
Sodium channel protein type 7 subunit alpha	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
C-terminal-binding protein 1	1	0	0	1
Leukotriene B4 receptor 1	0	0	0	1
Sodium channel protein type 9 subunit alpha	0	1	0	1
Potassium channel subfamily K member 2	0	1	0	1
Beta-2 adrenergic receptor	0	1	2	5
Indoleamine 2,3-dioxygenase 2	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Leukotriene B4 receptor 2	0	0	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Sodium channel protein type 11 subunit alpha	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	1	0	1
Sodium channel protein type 10 subunit alpha	0	1	0	1
Platelet-derived growth factor receptor beta	0	3	0	3
Platelet-derived growth factor receptor alpha	0	2	0	2
Vascular endothelial growth factor receptor 2	0	2	0	2
Cyclin-dependent kinase 10	0	0	2	2
Estrogen receptor	0	1	2	4
Progesterone receptor	0	3	2	5
Estrogen receptor beta	0	1	2	4
Alpha-1B adrenergic receptor	0	2	0	2
Alpha-2A adrenergic receptor	0	1	0	1
5-hydroxytryptamine receptor 1B	0	3	1	4
Type II pantothenate kinase	0	0	0	1
Type III pantothenate kinase	0	0	0	1
Quinolone resistance protein NorA	0	1	0	1
Beta-adrenergic receptor kinase 1	0	2	0	2
Potassium voltage-gated channel subfamily A member 3	0	1	0	1
Substance-P receptor	0	3	0	3
Rhodopsin kinase GRK1	0	1	0	1
G protein-coupled receptor kinase 5	0	2	0	2
G protein-coupled receptor kinase 5	0	1	0	1
D(1A) dopamine receptor	2	0	0	2
Envelope glycoprotein	0	0	1	1
P2X purinoceptor 4	0	1	0	1
Beta-adrenergic receptor kinase 1	0	0	0	1
Myosin light chain kinase, smooth muscle	0	0	3	3
Tubulin alpha-1A chain	0	0	3	3
Receptor protein-tyrosine kinase	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
Protease	0	3	0	3
Beta-2 adrenergic receptor	0	4	3	7
Beta-1 adrenergic receptor	0	6	3	9
POU domain, class 2, transcription factor 1	0	0	0	1
Beta-1 adrenergic receptor	0	5	1	7
mu-type opioid receptor isoform MOR-1	0	0	1	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Chain D, PROTEIN (PHOSPHOGLYCERATE MUTASE 1)	0	1	0	1
Chain A, PROTEIN (PHOSPHOGLYCERATE MUTASE 1)	0	1	0	1
Chain A, Beta-arrestin 1	0	0	1	1
heat shock protein 90, putative	0	0	0	1
Beta-2 adrenergic receptor	0	2	0	3
Beta-3 adrenergic receptor	0	2	0	2
Neuromedin-K receptor	0	0	1	1
Type-1 angiotensin II receptor	0	1	1	2
Cholecystokinin receptor type A	0	1	1	2
Beta-1 adrenergic receptor	0	1	0	1
Beta-2 adrenergic receptor	0	1	0	1
Nuclear receptor subfamily 2 group E member 1	0	0	2	2
Prolyl 4-hydroxylase, beta polypeptide	0	0	0	1
HLA class I histocompatibility antigen, A alpha chain	0	0	1	1
Gastric inhibitory polypeptide receptor	0	1	0	1
Chain A, Activated Factor Xa Heavy Chain	0	1	0	1
Suppressor of tumorigenicity 14 protein	0	1	0	1
Genome polyprotein	0	1	0	1
Lysine-specific histone demethylase 1A	0	1	0	1
L-lactate dehydrogenase A chain	0	1	0	1
Chymotrypsinogen A	0	1	0	1
Neuraminidase	0	1	0	1
Bifunctional epoxide hydrolase 2	0	3	0	3
Prolyl endopeptidase	0	1	0	1
Dihydroorotate dehydrogenase	0	1	0	1
Neuromedin-U receptor 2	0	0	1	1
Estrogen receptor beta	0	0	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Polymerase acidic protein	0	0	1	1
Stromelysin-1	0	1	1	2
Tyrosine-protein phosphatase YopH	0	1	0	1
High mobility group protein B1	0	0	1	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	3
Estrogen receptor	0	0	0	1
Cystathionine gamma-lyase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
photoreceptor-specific nuclear receptor	0	1	0	1
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	2	0	2
Insulin receptor	0	1	0	1
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
Eukaryotic translation initiation factor 4E	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	4	2	6
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	2	2
Peptidyl-prolyl cis-trans isomerase FKBP5	0	2	0	2
Uncharacterized aarF domain-containing protein kinase 5	0	0	2	2
Programmed cell death protein 4	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
melanocortin receptor 4	0	1	1	2
Tyrosine-protein kinase ABL1	0	1	0	1
Cyclin-C	0	1	1	2
Vascular endothelial growth factor receptor 3	0	1	0	1
5-hydroxytryptamine receptor 5A	0	1	0	1
Protein delta homolog 1	0	1	2	3
MAP kinase-activated protein kinase 3	0	0	1	1
Vascular endothelial growth factor receptor 2	0	1	0	1
Poly [ADP-ribose] polymerase tankyrase-2	0	0	2	2
RuvB-like 2	0	1	1	2
RuvB-like 1	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	1	0	1
Mast/stem cell growth factor receptor Kit	0	1	0	1
Serine/threonine-protein kinase ULK3	0	0	1	1
Bromodomain-containing protein 9	0	0	1	1
Serine/threonine-protein kinase 3	0	0	1	1
Bromodomain-containing protein 7	0	0	1	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	2	0	2
Splicing factor 3B subunit 3	0	1	0	1
Chain A, CES1 protein	0	1	0	1
Spike glycoprotein	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Transmembrane protease serine 2	0	0	1	1
Lysosomal acid glucosylceramidase	0	0	1	1
Protein kinase C gamma type	0	2	1	3
Protein kinase C alpha type	0	1	0	1
Procathepsin L	0	0	1	1
Protein kinase C delta type	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Replicase polyprotein 1a	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Transcriptional activator protein LuxR	0	1	0	1
D(4) dopamine receptor	0	2	0	2
Melanocortin receptor 4	0	2	0	2
C-8 sterol isomerase	0	1	0	1
Melanocortin receptor 5	0	2	0	2
Melanocortin receptor 3	0	2	0	2
Protein kinase C gamma type	0	1	0	1
Protein kinase C beta type	0	1	0	1
Phospholipase D1	0	1	0	1
Platelet-activating factor acetylhydrolase	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	2	1	3
Protein kinase C eta type	0	1	0	1
Emopamil-binding protein-like	0	1	0	1
Angiotensin-converting enzyme 2	0	0	1	1
7-dehydrocholesterol reductase	0	1	1	2
Protein kinase C theta type	0	1	0	1
Luciferin 4-monooxygenase	0	0	1	1
Ras guanyl-releasing protein 3	0	0	1	1
Chain A, PLASMINOGEN	0	0	1	1
Chain A, PLASMINOGEN	0	0	1	1
Urokinase-type plasminogen activator	0	1	0	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
Tryptophan 2,3-dioxygenase	0	1	0	2
SLC16A10 protein	0	0	0	2
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Tryprostatin B synthase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Monocarboxylate transporter 10	0	0	0	2
Phospholipase A-2-activating protein	0	1	0	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Tubulin--tyrosine ligase	0	1	0	1
Taste receptor type 2 member 14	0	0	0	1
D-alanyl-D-alanine dipeptidase	0	1	0	1
Albumin	0	0	1	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Telangiectasia, Hereditary Hemorrhagic

Synonyms(1)

Research Excerpts

Overview

Context

Research

Studies (501)

Protein Targets (1,806)

Telangiectasia, Hereditary Hemorrhagic

Synonyms(1)

Research Excerpts

Overview

Context

Research

Studies (501)

Drugs Studied (224)

Protein Targets (1,806)