Page last updated: 2024-09-27

Stenosis, Pulmonary Artery

Narrowing of the PULMONARY ARTERIES.

Synonyms(1)

Synonym
Stenosis, Pulmonary Artery

Research

Studies (9)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's0 (0.00)12.5806
2000's0 (0.00)18.1394
2010's4 (44.44)28.8240
2020's5 (55.56)9.53
DrugIndicatedRelationship StrengthStudiesTrials
azathioprine0low10
isoniazid0low10
mexiletine0low10
prednisolone0low10
cycloheximide0low10
fluorodeoxyglucose f180low10
methotrexate0low10
elastin0low30
entecavir0low10
guanine0low10

Protein Targets (311)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE4004
Chain A, TYROSYL-DNA PHOSPHODIESTERASE2002
Chain A, Ferritin light chain2002
interleukin 82002
acetylcholinesterase1001
thioredoxin reductase2002
phosphopantetheinyl transferase3003
RAR-related orphan receptor gamma4004
SMAD family member 21001
ATAD5 protein, partial3003
Fumarate hydratase2002
SMAD family member 31001
TDP1 protein5005
GLI family zinc finger 34004
Microtubule-associated protein tau2002
AR protein5005
thioredoxin glutathione reductase1001
nuclear receptor subfamily 1, group I, member 34004
EWS/FLI fusion protein4004
glucocorticoid receptor [Homo sapiens]3003
retinoic acid nuclear receptor alpha variant 14004
retinoid X nuclear receptor alpha3003
estrogen-related nuclear receptor alpha4004
farnesoid X nuclear receptor3003
pregnane X nuclear receptor2002
estrogen nuclear receptor alpha5005
G1001
polyprotein2002
P532002
peroxisome proliferator-activated receptor delta3003
peroxisome proliferator activated receptor gamma3003
arylsulfatase A1001
IDH13003
euchromatic histone-lysine N-methyltransferase 23003
aryl hydrocarbon receptor4004
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a3003
thyroid stimulating hormone receptor1001
activating transcription factor 62002
v-jun sarcoma virus 17 oncogene homolog (avian)3003
Histone H2A.x3003
Bloom syndrome protein isoform 12002
peripheral myelin protein 22 isoform 11001
hemoglobin subunit beta1001
cellular tumor antigen p53 isoform a3003
thyroid hormone receptor beta isoform 24004
heat shock protein beta-11001
nuclear factor erythroid 2-related factor 2 isoform 14004
DNA polymerase iota isoform a (long)2002
geminin4004
peripheral myelin protein 222002
survival motor neuron protein isoform d3003
cytochrome P450 3A4 isoform 13003
M-phase phosphoprotein 82002
muscleblind-like protein 1 isoform 12002
muscarinic acetylcholine receptor M11001
lamin isoform A-delta102002
Gamma-aminobutyric acid receptor subunit pi3003
ATP-binding cassette sub-family C member 30606
Multidrug resistance-associated protein 40607
Bile salt export pump0303
Voltage-dependent calcium channel gamma-2 subunit4004
Bile salt export pump0606
Interferon beta3003
HLA class I histocompatibility antigen, B alpha chain 1001
Cellular tumor antigen p534004
Gamma-aminobutyric acid receptor subunit beta-13003
Gamma-aminobutyric acid receptor subunit delta3003
Gamma-aminobutyric acid receptor subunit gamma-23003
Glutamate receptor 24004
Gamma-aminobutyric acid receptor subunit alpha-53003
Gamma-aminobutyric acid receptor subunit alpha-33003
Gamma-aminobutyric acid receptor subunit gamma-13003
Gamma-aminobutyric acid receptor subunit alpha-23003
Gamma-aminobutyric acid receptor subunit alpha-43003
Gamma-aminobutyric acid receptor subunit gamma-33003
Gamma-aminobutyric acid receptor subunit alpha-63003
Nuclear receptor ROR-gamma2002
Gamma-aminobutyric acid receptor subunit alpha-13003
Gamma-aminobutyric acid receptor subunit beta-33003
Gamma-aminobutyric acid receptor subunit beta-23003
GABA theta subunit3003
Inositol hexakisphosphate kinase 11001
Canalicular multispecific organic anion transporter 10606
ATPase family AAA domain-containing protein 54004
Ataxin-24004
Gamma-aminobutyric acid receptor subunit epsilon3003
Protein-arginine deiminase type-40202
cytochrome P450 2C9, partial1001
glp-1 receptor, partial1001
pregnane X receptor1001
USP1 protein, partial2002
PPM1D protein1001
Smad31001
aldehyde dehydrogenase 1 family, member A12002
estrogen receptor 2 (ER beta)2002
progesterone receptor3003
67.9K protein3003
vitamin D (1,25- dihydroxyvitamin D3) receptor3003
RPL19A0011
Spike glycoprotein0011
Replicase polyprotein 1ab0011
NPC intracellular cholesterol transporter 1 precursor1001
chromobox protein homolog 13003
thyroid hormone receptor beta isoform a1001
nuclear factor erythroid 2-related factor 2 isoform 23003
nuclear factor NF-kappa-B p105 subunit isoform 11001
ras-related protein Rab-9A1001
heat shock protein HSP 90-alpha isoform 20001
urokinase-type plasminogen activator precursor1001
plasminogen precursor1001
urokinase plasminogen activator surface receptor precursor1001
nuclear receptor ROR-gamma isoform 12002
transactivating tegument protein VP16 [Human herpesvirus 1]0202
COUP transcription factor 2 isoform a0101
lethal factor (plasmid)1001
Transmembrane protease serine 20011
Glucose transporter0101
Hexose transporter 1 0101
Procathepsin L0011
Polyunsaturated fatty acid 5-lipoxygenase0101
Replicase polyprotein 1a0011
Replicase polyprotein 1ab0011
Replicase polyprotein 1ab0011
Replicase polyprotein 1ab0011
Solute carrier family 2, facilitated glucose transporter member 10101
Alpha-synuclein1001
Spike glycoprotein2013
Eukaryotic initiation factor 4A-I0101
Peptidyl-prolyl cis-trans isomerase FKBP1A0202
Peptidyl-prolyl cis-trans isomerase FKBP30101
Peptidyl-prolyl cis-trans isomerase FKBP40101
TAR DNA-binding protein 432002
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 10101
Hypoxia-inducible factor 1-alpha0101
Endothelial PAS domain-containing protein 10101
Angiotensin-converting enzyme 2 0011
Peptidyl-prolyl cis-trans isomerase FKBP140101
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 40101
heat shock protein 90, putative0001
Capsid protein 0011
Purine nucleoside phosphorylase0202
Hypoxanthine-guanine phosphoribosyltransferase0001
Ricin0101
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase0011
Purine nucleoside phosphorylase 0012
Shiga toxin subunit A0101
Guanine deaminase0001
Chain A, 2-oxoglutarate Oxygenase2002
Luciferase1001
GLS protein1001
cytochrome P450 family 3 subfamily A polypeptide 42002
bromodomain adjacent to zinc finger domain 2B1001
3-oxoacyl-[acyl-carrier-protein] synthase 3 0101
cytochrome P450 2D6 isoform 11001
potassium voltage-gated channel subfamily H member 2 isoform d1001
histone acetyltransferase KAT2A isoform 12002
N-glycosylase/DNA lyase0101
Polyphenol oxidase 20101
Myeloperoxidase0101
Cytochrome P450 1A20101
Formamidopyrimidine-DNA glycosylase0101
Cytochrome P450 3A40101
DNA gyrase subunit A0101
DNA gyrase subunit B0101
Cytochrome P450 2C80101
Cytochrome P450 2A60101
Macrophage migration inhibitory factor0101
Cytochrome P450 2C190101
Endonuclease III-like protein 10101
DNA gyrase subunit B0101
DNA gyrase subunit A0101
Enoyl-[acyl-carrier-protein] reductase [NADH]0102
Pantothenate synthetase0101
Isocitrate lyase0101
Putative FAD-containing monooxygenase MymA0101
Dihydrofolate reductase0202
Endonuclease 8-like 10101
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain A, HADH2 protein1001
Chain B, HADH2 protein1001
acid sphingomyelinase1001
dopamine D1 receptor1001
ClpP1001
15-lipoxygenase, partial1001
Thymidylate synthase 0101
alpha-galactosidase1001
Thymidylate synthase 0101
polyunsaturated fatty acid lipoxygenase ALOX121001
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 11001
vitamin D3 receptor isoform VDRA1001
transcriptional regulator ERG isoform 31001
importin subunit beta-1 isoform 11001
DNA polymerase beta1001
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0101
flap endonuclease 11001
snurportin-11001
peptidyl-prolyl cis-trans isomerase NIMA-interacting 12002
DNA polymerase eta isoform 11001
DNA polymerase kappa isoform 11001
caspase-1 isoform alpha precursor1001
nuclear receptor coactivator 3 isoform a0101
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0203
Dihydrofolate reductase0203
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Tyrosine-protein kinase ABL10011
Carbonic anhydrase 20011
Thymidylate synthase0202
Integrin beta-31001
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Thymidylate synthase0202
Integrin alpha-IIb1001
5-hydroxytryptamine receptor 2C0102
High mobility group protein B10011
Dihydrofolate reductase0101
Thymidylate synthase0101
Dihydrofolate reductase0224
Glucose-6-phosphate 1-dehydrogenase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0101
5-hydroxytryptamine receptor 2A0101
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Dihydrofolate reductase0202
Histidine decarboxylase0101
Trifunctional purine biosynthetic protein adenosine-30101
Cyclin-dependent kinase 20011
Bifunctional purine biosynthesis protein ATIC0202
Multidrug resistance-associated protein 1 0001
Delta-type opioid receptor0101
Mu-type opioid receptor0101
Kappa-type opioid receptor0101
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
6-phosphogluconate dehydrogenase, decarboxylating0101
Caspase-71001
Solute carrier organic anion transporter family member 1A30001
Pteridine reductase 10101
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Solute carrier family 22 member 60001
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Solute carrier family 22 member 200101
Dihydrofolate reductase 0101
Solute carrier family 22 member 80001
Solute carrier family 22 member 60101
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Multidrug resistance associated protein0102
Solute carrier organic anion transporter family member 1B30001
Solute carrier family 22 member 110001
Broad substrate specificity ATP-binding cassette transporter ABCG20001
ATP-dependent phosphofructokinase2002
cytochrome P450 2D61001
D(1A) dopamine receptor1001
Potassium channel subfamily K member 30101
Voltage-dependent L-type calcium channel subunit alpha-1F0101
Potassium channel subfamily K member 20101
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0101
Cytochrome P450 2C9 0202
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 4 subunit alpha0101
5-hydroxytryptamine receptor 2B0202
Cytochrome P450 2J20202
Sodium channel protein type 7 subunit alpha0101
Voltage-dependent L-type calcium channel subunit alpha-1D 0101
Potassium voltage-gated channel subfamily H member 20101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Sodium channel protein type 5 subunit alpha0101
Sodium channel protein type 9 subunit alpha0202
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0101
Sodium channel protein type 11 subunit alpha0101
Sodium channel protein type 8 subunit alpha0101
Sodium channel protein type 10 subunit alpha0101
luciferase0001
hypoxia-inducible factor 1 alpha subunit1001
nuclear receptor subfamily 1, group I, member 21001
Fatty acid-binding protein, liver0101
Estrogen receptor0202
Glucocorticoid receptor0218
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Glycine receptor subunit alpha-10202
Corticosteroid-binding globulin0101
Mineralocorticoid receptor 0213
Androgen receptor0202
Glutamine synthetase0011
Androgen receptor0101
Glycine receptor subunit beta0202
Glycine receptor subunit alpha-20202
Glycine receptor subunit alpha-30202
Histamine H1 receptor0011
Prostaglandin G/H synthase 20101
Nociceptin receptor0011
Estrogen receptor beta0202
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]