| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| glp-1 receptor, partial | 1 | 0 | 0 | 1 |
| TDP1 protein | 1 | 0 | 0 | 1 |
| AR protein | 3 | 0 | 0 | 3 |
| IDH1 | 1 | 0 | 0 | 1 |
| potassium voltage-gated channel subfamily H member 2 isoform d | 2 | 0 | 0 | 2 |
| geminin | 3 | 0 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit pi | 0 | 1 | 0 | 1 |
| ATP-binding cassette sub-family C member 3 | 0 | 3 | 0 | 3 |
| Multidrug resistance-associated protein 4 | 0 | 3 | 0 | 3 |
| Bile salt export pump | 0 | 4 | 0 | 4 |
| Cellular tumor antigen p53 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 0 | 1 | 0 | 1 |
| Translocator protein | 0 | 1 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit delta | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 1A | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 0 | 1 | 0 | 1 |
| Cholecystokinin receptor type A | 0 | 1 | 0 | 1 |
| Gastrin/cholecystokinin type B receptor | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 0 | 1 | 0 | 1 |
| Histamine H1 receptor | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 0 | 1 | 0 | 1 |
| GABA theta subunit | 0 | 1 | 0 | 1 |
| Canalicular multispecific organic anion transporter 1 | 0 | 3 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit epsilon | 0 | 1 | 0 | 1 |
| Mas-related G-protein coupled receptor member X2 | 0 | 0 | 3 | 3 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 1 | 0 | 0 | 1 |
| phosphopantetheinyl transferase | 1 | 0 | 0 | 1 |
| regulator of G-protein signaling 4 | 1 | 0 | 0 | 1 |
| DNA polymerase kappa isoform 1 | 1 | 0 | 0 | 1 |
| 5-hydroxytryptamine receptor 2A | 0 | 2 | 0 | 2 |
| Delta-type opioid receptor | 0 | 2 | 0 | 3 |
| Kappa-type opioid receptor | 0 | 3 | 2 | 6 |
| Mu-type opioid receptor | 0 | 3 | 1 | 7 |
| Kappa-type opioid receptor | 0 | 3 | 2 | 6 |
| Mu-type opioid receptor | 0 | 3 | 2 | 6 |
| Delta-type opioid receptor | 0 | 3 | 2 | 6 |
| Kappa-type opioid receptor | 0 | 3 | 1 | 4 |
| Kappa-type opioid receptor | 0 | 4 | 2 | 7 |
| Mu-type opioid receptor | 0 | 3 | 0 | 3 |
| RAR-related orphan receptor gamma | 1 | 0 | 0 | 1 |
| aldehyde dehydrogenase 1 family, member A1 | 2 | 0 | 0 | 2 |
| estrogen receptor 2 (ER beta) | 2 | 0 | 0 | 2 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 1 | 0 | 0 | 1 |
| EWS/FLI fusion protein | 1 | 0 | 0 | 1 |
| retinoic acid nuclear receptor alpha variant 1 | 1 | 0 | 0 | 1 |
| farnesoid X nuclear receptor | 1 | 0 | 0 | 1 |
| estrogen nuclear receptor alpha | 2 | 0 | 0 | 2 |
| aryl hydrocarbon receptor | 1 | 0 | 0 | 1 |
| thyrotropin-releasing hormone receptor | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform 2 | 1 | 0 | 0 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 2 | 0 | 0 | 2 |
| Solute carrier family 22 member 6 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 12 | 0 | 1 | 0 | 2 |
| Bile salt export pump | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 1 | 0 | 1 | 0 | 2 |
| Carbonic anhydrase 2 | 0 | 1 | 0 | 2 |
| Albumin | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 3 | 0 | 1 | 0 | 1 |
| Glucose-6-phosphate 1-dehydrogenase | 0 | 1 | 0 | 1 |
| Cytochrome P450 2C9 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 4 | 0 | 1 | 0 | 2 |
| Carbonic anhydrase 6 | 0 | 1 | 0 | 2 |
| Serum paraoxonase/arylesterase 1 | 0 | 1 | 0 | 1 |
| Corticosteroid 11-beta-dehydrogenase isozyme 1 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 5A, mitochondrial | 0 | 1 | 0 | 2 |
| Carbonic anhydrase 7 | 0 | 1 | 0 | 2 |
| Adenosine receptor A1 | 0 | 1 | 0 | 1 |
| Corticosteroid 11-beta-dehydrogenase isozyme 1 | 0 | 1 | 0 | 1 |
| Cytochrome P450 2J2 | 0 | 1 | 0 | 1 |
| 6-phosphogluconate dehydrogenase, decarboxylating | 0 | 2 | 0 | 2 |
| Spike glycoprotein | 1 | 0 | 0 | 1 |
| Holo-[acyl-carrier-protein] synthase | 0 | 1 | 0 | 1 |
| Solute carrier organic anion transporter family member 2A1 | 0 | 1 | 0 | 1 |
| Sodium/bile acid cotransporter | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 9 | 0 | 1 | 0 | 2 |
| Multidrug and toxin extrusion protein 1 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 13 | 0 | 1 | 0 | 2 |
| G-protein coupled receptor 35 | 0 | 1 | 1 | 2 |
| CDGSH iron-sulfur domain-containing protein 1 | 0 | 2 | 0 | 2 |
| Carbonic anhydrase 14 | 0 | 1 | 0 | 2 |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 5B, mitochondrial | 0 | 1 | 0 | 2 |
| USP1 protein, partial | 1 | 0 | 0 | 1 |
| GLI family zinc finger 3 | 1 | 0 | 0 | 1 |
| glucocorticoid receptor [Homo sapiens] | 2 | 0 | 0 | 2 |
| retinoid X nuclear receptor alpha | 1 | 0 | 0 | 1 |
| estrogen-related nuclear receptor alpha | 1 | 0 | 0 | 1 |
| activating transcription factor 6 | 1 | 0 | 0 | 1 |
| lethal(3)malignant brain tumor-like protein 1 isoform I | 1 | 0 | 0 | 1 |
| lamin isoform A-delta10 | 2 | 0 | 0 | 2 |
| TAR DNA-binding protein 43 | 1 | 0 | 0 | 1 |
| 5-hydroxytryptamine receptor 3E | 0 | 0 | 1 | 1 |
| acetylcholinesterase | 1 | 0 | 0 | 1 |
| cytochrome P450 2D6 | 1 | 0 | 0 | 1 |
| euchromatic histone-lysine N-methyltransferase 2 | 1 | 0 | 0 | 1 |
| cytochrome P450 2D6 isoform 1 | 1 | 0 | 0 | 1 |
| D(1A) dopamine receptor | 1 | 0 | 0 | 1 |
| muscarinic acetylcholine receptor M1 | 1 | 0 | 0 | 1 |
| Solute carrier family 22 member 1 | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 4 | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 3B | 0 | 0 | 1 | 1 |
| Albumin | 0 | 0 | 1 | 1 |
| Myeloperoxidase | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 2C | 0 | 1 | 0 | 1 |
| Alpha-2A adrenergic receptor | 0 | 2 | 1 | 3 |
| Cytochrome P450 2D6 | 0 | 2 | 0 | 2 |
| D(2) dopamine receptor | 0 | 2 | 0 | 2 |
| Alpha-1B adrenergic receptor | 0 | 1 | 0 | 1 |
| D | 0 | 1 | 0 | 1 |
| D(3) dopamine receptor | 0 | 1 | 0 | 1 |
| Alpha-2B adrenergic receptor | 0 | 1 | 0 | 1 |
| D(2) dopamine receptor | 0 | 1 | 0 | 1 |
| Alpha-2C adrenergic receptor | 0 | 1 | 0 | 1 |
| Acetylcholinesterase | 0 | 1 | 0 | 1 |
| Alpha-2A adrenergic receptor | 0 | 1 | 0 | 1 |
| Alpha-1D adrenergic receptor | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 3A | 0 | 1 | 0 | 1 |
| D(1B) dopamine receptor | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 2A | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 2C | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 1B | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 1D | 0 | 1 | 0 | 1 |
| D(4) dopamine receptor | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 1F | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 2B | 0 | 1 | 0 | 1 |
| D(3) dopamine receptor | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 3A | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 2B | 0 | 2 | 0 | 2 |
| Alpha-1A adrenergic receptor | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 3A | 0 | 0 | 1 | 1 |
| 5-hydroxytryptamine receptor 7 | 0 | 2 | 0 | 2 |
| D(2) dopamine receptor | 0 | 2 | 0 | 2 |
| Lactoperoxidase | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 4 | 0 | 1 | 0 | 2 |
| 5-hydroxytryptamine receptor 3D | 0 | 0 | 1 | 1 |
| 5-hydroxytryptamine receptor 3C | 0 | 0 | 1 | 1 |
| 5-hydroxytryptamine receptor 3B | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 3B | 0 | 2 | 0 | 2 |
| Opioid receptor, delta 1b | 0 | 1 | 0 | 1 |
| Acetylcholinesterase | 0 | 1 | 0 | 1 |
| Opioid receptor homologue | 0 | 1 | 0 | 1 |
| ATP-dependent translocase ABCB1 | 0 | 1 | 0 | 1 |
| Acyl-CoA desaturase 1 | 0 | 1 | 0 | 1 |
| ATP-dependent translocase ABCB1 | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M1 | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M3 | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M4 | 0 | 1 | 0 | 1 |
| Cytochrome P450 3A4 | 0 | 1 | 1 | 2 |
| Muscarinic acetylcholine receptor M5 | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M2 | 0 | 1 | 0 | 1 |
| Histidine decarboxylase | 0 | 0 | 1 | 1 |
| ATP-dependent translocase ABCB1 | 0 | 1 | 0 | 1 |
| Proteinase-activated receptor 1 | 0 | 1 | 1 | 2 |
| Sodium-dependent serotonin transporter | 0 | 1 | 0 | 1 |
| Delta-type opioid receptor | 0 | 2 | 1 | 4 |
| UDP-glucuronosyltransferase 1A3 | 0 | 0 | 0 | 1 |
| Mu-type opioid receptor | 0 | 2 | 1 | 5 |
| Nociceptin receptor | 0 | 1 | 0 | 1 |
| Mu-type opioid receptor | 0 | 1 | 0 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | 0 | 1 | 0 | 1 |
| Beta-2 adrenergic receptor | 0 | 1 | 0 | 1 |
| Mu-type opioid receptor | 0 | 1 | 0 | 1 |
| Sigma non-opioid intracellular receptor 1 | 0 | 1 | 0 | 1 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |