| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 4 | 0 | 0 | 4 |
| Chain A, HADH2 protein | 2 | 0 | 0 | 2 |
| Chain B, HADH2 protein | 2 | 0 | 0 | 2 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | 2 | 0 | 0 | 2 |
| Chain A, 2-oxoglutarate Oxygenase | 4 | 0 | 0 | 4 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | 1 | 0 | 0 | 1 |
| Luciferase | 2 | 0 | 0 | 2 |
| endonuclease IV | 2 | 0 | 0 | 2 |
| 15-lipoxygenase, partial | 4 | 0 | 0 | 4 |
| WRN | 1 | 0 | 0 | 1 |
| RAR-related orphan receptor gamma | 7 | 0 | 0 | 7 |
| USP1 protein, partial | 5 | 0 | 0 | 5 |
| Microtubule-associated protein tau | 4 | 0 | 0 | 4 |
| AR protein | 11 | 0 | 0 | 11 |
| aldehyde dehydrogenase 1 family, member A1 | 6 | 0 | 0 | 6 |
| estrogen receptor 2 (ER beta) | 5 | 0 | 0 | 5 |
| nuclear receptor subfamily 1, group I, member 3 | 8 | 0 | 0 | 8 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 8 | 0 | 0 | 8 |
| retinoid X nuclear receptor alpha | 7 | 0 | 0 | 7 |
| estrogen nuclear receptor alpha | 11 | 0 | 0 | 11 |
| G | 4 | 0 | 0 | 4 |
| cytochrome P450 2D6 | 4 | 0 | 0 | 4 |
| peroxisome proliferator activated receptor gamma | 6 | 0 | 0 | 6 |
| aryl hydrocarbon receptor | 5 | 0 | 0 | 5 |
| thyroid stimulating hormone receptor | 4 | 0 | 0 | 4 |
| Histone H2A.x | 3 | 0 | 0 | 3 |
| polyunsaturated fatty acid lipoxygenase ALOX12 | 1 | 0 | 0 | 1 |
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | 2 | 0 | 0 | 2 |
| chromobox protein homolog 1 | 6 | 0 | 0 | 6 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | 3 | 0 | 0 | 4 |
| potassium voltage-gated channel subfamily H member 2 isoform d | 4 | 0 | 0 | 4 |
| histone deacetylase 9 isoform 3 | 2 | 0 | 0 | 2 |
| importin subunit beta-1 isoform 1 | 3 | 0 | 0 | 3 |
| mitogen-activated protein kinase 1 | 2 | 0 | 0 | 2 |
| flap endonuclease 1 | 1 | 0 | 0 | 1 |
| serine/threonine-protein kinase PLK1 | 1 | 0 | 0 | 1 |
| snurportin-1 | 3 | 0 | 0 | 3 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 9 | 0 | 0 | 9 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | 2 | 0 | 0 | 2 |
| tumor susceptibility gene 101 protein | 1 | 0 | 0 | 1 |
| DNA polymerase eta isoform 1 | 1 | 0 | 0 | 1 |
| DNA polymerase iota isoform a (long) | 3 | 0 | 0 | 3 |
| dual specificity tyrosine-phosphorylation-regulated kinase 1A | 0 | 0 | 0 | 1 |
| geminin | 10 | 0 | 0 | 10 |
| DNA polymerase kappa isoform 1 | 2 | 0 | 0 | 2 |
| Vpr | 2 | 0 | 0 | 2 |
| survival motor neuron protein isoform d | 2 | 0 | 0 | 2 |
| cytochrome P450 3A4 isoform 1 | 3 | 0 | 0 | 3 |
| histone acetyltransferase KAT2A isoform 1 | 2 | 0 | 0 | 2 |
| kelch-like ECH-associated protein 1 | 0 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit pi | 3 | 0 | 0 | 3 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | 1 | 0 | 0 | 1 |
| Interferon beta | 5 | 0 | 0 | 5 |
| HLA class I histocompatibility antigen, B alpha chain | 4 | 0 | 0 | 4 |
| Transthyretin | 0 | 1 | 0 | 1 |
| Gag-Pol polyprotein | 0 | 1 | 0 | 1 |
| Cellular tumor antigen p53 | 10 | 0 | 0 | 10 |
| Apoptosis regulator Bcl-2 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 3 | 0 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit delta | 3 | 0 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 3 | 0 | 0 | 3 |
| D(3) dopamine receptor | 0 | 1 | 0 | 1 |
| Glutamate receptor 1 | 1 | 0 | 0 | 1 |
| Glutamate receptor 2 | 4 | 0 | 0 | 4 |
| Glutamate receptor 3 | 1 | 0 | 0 | 1 |
| Glutamate receptor 4 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 3 | 0 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 3 | 0 | 0 | 3 |
| Amine oxidase [flavin-containing] A | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 3 | 0 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 3 | 0 | 0 | 3 |
| Amine oxidase [flavin-containing] B | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 3 | 0 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 3 | 0 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 3 | 0 | 0 | 3 |
| Histamine H2 receptor | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 3 | 0 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 3 | 0 | 0 | 3 |
| Guanine nucleotide-binding protein G | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 3 | 0 | 0 | 3 |
| Inositol monophosphatase 1 | 1 | 0 | 0 | 1 |
| Induced myeloid leukemia cell differentiation protein Mcl-1 | 0 | 1 | 0 | 1 |
| TAR DNA-binding protein 43 | 2 | 0 | 0 | 2 |
| Cytochrome P450 1B1 | 0 | 1 | 0 | 1 |
| RmtA | 0 | 1 | 0 | 1 |
| Reverse transcriptase/RNaseH | 0 | 1 | 0 | 1 |
| GABA theta subunit | 3 | 0 | 0 | 3 |
| Inositol hexakisphosphate kinase 1 | 4 | 0 | 0 | 4 |
| Protein arginine N-methyltransferase 1 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | 3 | 0 | 0 | 3 |
| cytochrome P450 2C9, partial | 4 | 0 | 0 | 4 |
| phosphoglycerate kinase | 1 | 0 | 0 | 1 |
| Chain A, Beta-lactamase | 2 | 0 | 0 | 2 |
| interleukin 8 | 2 | 0 | 0 | 2 |
| glp-1 receptor, partial | 4 | 0 | 0 | 4 |
| pregnane X receptor | 2 | 0 | 0 | 2 |
| ATAD5 protein, partial | 1 | 0 | 0 | 1 |
| Fumarate hydratase | 3 | 0 | 0 | 3 |
| NFKB1 protein, partial | 1 | 0 | 0 | 1 |
| PPM1D protein | 1 | 0 | 0 | 1 |
| TDP1 protein | 10 | 0 | 0 | 10 |
| GLI family zinc finger 3 | 6 | 0 | 0 | 6 |
| Thrombopoietin | 1 | 0 | 0 | 1 |
| Smad3 | 3 | 0 | 0 | 3 |
| progesterone receptor | 3 | 0 | 0 | 3 |
| glucocorticoid receptor [Homo sapiens] | 6 | 0 | 0 | 6 |
| retinoic acid nuclear receptor alpha variant 1 | 7 | 0 | 0 | 7 |
| estrogen-related nuclear receptor alpha | 8 | 0 | 0 | 8 |
| farnesoid X nuclear receptor | 2 | 0 | 0 | 2 |
| pregnane X nuclear receptor | 6 | 0 | 0 | 6 |
| polyprotein | 3 | 0 | 0 | 3 |
| 67.9K protein | 6 | 0 | 0 | 6 |
| Parkin | 1 | 0 | 0 | 1 |
| peroxisome proliferator-activated receptor delta | 5 | 0 | 0 | 5 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | 3 | 0 | 0 | 3 |
| arylsulfatase A | 1 | 0 | 0 | 1 |
| IDH1 | 3 | 0 | 0 | 3 |
| euchromatic histone-lysine N-methyltransferase 2 | 5 | 0 | 0 | 5 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 6 | 0 | 0 | 6 |
| activating transcription factor 6 | 2 | 0 | 0 | 2 |
| Bloom syndrome protein isoform 1 | 2 | 0 | 0 | 2 |
| peripheral myelin protein 22 isoform 1 | 1 | 0 | 0 | 1 |
| hemoglobin subunit beta | 1 | 0 | 0 | 1 |
| cellular tumor antigen p53 isoform a | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform 2 | 7 | 0 | 0 | 7 |
| huntingtin isoform 2 | 1 | 0 | 0 | 1 |
| ras-related protein Rab-9A | 1 | 0 | 0 | 1 |
| serine/threonine-protein kinase mTOR isoform 1 | 2 | 0 | 0 | 2 |
| urokinase-type plasminogen activator precursor | 4 | 0 | 0 | 4 |
| plasminogen precursor | 4 | 0 | 0 | 4 |
| urokinase plasminogen activator surface receptor precursor | 4 | 0 | 0 | 4 |
| peripheral myelin protein 22 | 5 | 0 | 0 | 5 |
| muscarinic acetylcholine receptor M1 | 1 | 0 | 0 | 1 |
| lamin isoform A-delta10 | 6 | 0 | 0 | 6 |
| Integrin beta-3 | 1 | 0 | 0 | 1 |
| Integrin alpha-IIb | 1 | 0 | 0 | 1 |
| Adenosine receptor A3 | 0 | 1 | 0 | 1 |
| DNA (cytosine-5)-methyltransferase 1 | 0 | 1 | 0 | 1 |
| Adenosine receptor A2a | 0 | 1 | 0 | 1 |
| Adenosine receptor A1 | 0 | 1 | 0 | 1 |
| D(1A) dopamine receptor | 2 | 0 | 0 | 2 |
| Nuclear receptor ROR-gamma | 3 | 0 | 0 | 3 |
| Spike glycoprotein | 4 | 0 | 0 | 4 |
| Multidrug and toxin extrusion protein 1 | 0 | 1 | 0 | 1 |
| Histone-lysine N-methyltransferase EHMT2 | 0 | 1 | 0 | 1 |
| ATPase family AAA domain-containing protein 5 | 3 | 0 | 0 | 3 |
| Ataxin-2 | 4 | 0 | 0 | 4 |
| ATP-dependent phosphofructokinase | 2 | 0 | 0 | 2 |
| apical membrane antigen 1, AMA1 | 1 | 0 | 0 | 1 |
| thyroid stimulating hormone receptor | 2 | 0 | 0 | 2 |
| EWS/FLI fusion protein | 6 | 0 | 0 | 6 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | 2 | 0 | 0 | 2 |
| ubiquitin carboxyl-terminal hydrolase 2 isoform a | 2 | 0 | 0 | 2 |
| lethal factor (plasmid) | 1 | 0 | 0 | 1 |
| ATP-binding cassette sub-family C member 3 | 0 | 4 | 0 | 4 |
| Multidrug resistance-associated protein 4 | 0 | 4 | 0 | 4 |
| Bile salt export pump | 0 | 4 | 0 | 4 |
| Matrix metalloproteinase-9 | 0 | 1 | 0 | 1 |
| Disintegrin and metalloproteinase domain-containing protein 17 | 2 | 0 | 0 | 2 |
| Canalicular multispecific organic anion transporter 1 | 0 | 3 | 0 | 3 |
| Carbonic anhydrase 1 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 2 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 4 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 15 | 0 | 1 | 0 | 1 |
| thioredoxin reductase | 6 | 0 | 0 | 6 |
| phosphopantetheinyl transferase | 4 | 0 | 0 | 4 |
| LMP1 [Human herpesvirus 4] | 0 | 0 | 0 | 2 |
| thyroid hormone receptor beta isoform a | 1 | 0 | 0 | 1 |
| nuclear receptor coactivator 1 isoform 1 [Homo sapiens] | 0 | 1 | 0 | 1 |
| transactivating tegument protein VP16 [Human herpesvirus 1] | 0 | 1 | 0 | 1 |
| nuclear receptor coactivator 3 isoform a | 0 | 1 | 0 | 1 |
| Thymidine kinase 2, mitochondrial | 0 | 1 | 0 | 1 |
| Voltage-dependent calcium channel gamma-2 subunit | 3 | 0 | 0 | 3 |
| Thymidine kinase, cytosolic | 0 | 1 | 0 | 2 |
| Thymidine kinase | 0 | 1 | 0 | 1 |
| Thymidylate synthase | 0 | 0 | 0 | 1 |
| Cytochrome P450 3A4 | 0 | 1 | 0 | 1 |
| Thymidine kinase | 0 | 1 | 0 | 1 |
| Deoxycytidine kinase | 0 | 0 | 0 | 1 |
| Probable deoxycytidylate deaminase | 0 | 0 | 0 | 1 |
| Cytidine deaminase | 0 | 1 | 0 | 2 |
| E3 ubiquitin-protein ligase Mdm2 | 0 | 1 | 0 | 1 |
| Enoyl-[acyl-carrier-protein] reductase [NADH] | 0 | 1 | 0 | 1 |
| Thymidine kinase | 0 | 1 | 0 | 1 |
| Deoxynucleoside kinase | 0 | 1 | 0 | 1 |
| heat shock protein beta-1 | 2 | 0 | 0 | 2 |
| GTP-binding nuclear protein Ran isoform 1 | 1 | 0 | 0 | 1 |
| Rap guanine nucleotide exchange factor 3 | 1 | 0 | 0 | 1 |
| Glutathione S-transferase P | 0 | 1 | 0 | 1 |
| Alpha-tocopherol transfer protein | 0 | 0 | 1 | 1 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 3 | 0 | 0 | 3 |
| corticotropin-releasing hormone receptor 2 | 0 | 1 | 1 | 2 |
| corticotropin releasing factor-binding protein | 0 | 1 | 1 | 2 |
| glycogen synthase kinase-3 beta isoform 1 | 0 | 0 | 2 | 2 |
| 5'-nucleotidase | 0 | 1 | 0 | 1 |
| Adenosine receptor A3 | 0 | 1 | 0 | 1 |
| Adenosine deaminase | 0 | 0 | 0 | 2 |
| Glycogen phosphorylase, muscle form | 0 | 1 | 0 | 1 |
| Pancreatic alpha-amylase | 0 | 1 | 0 | 1 |
| Beta-glucuronidase | 0 | 1 | 0 | 1 |
| Beta-glucuronidase | 0 | 1 | 0 | 1 |
| High mobility group protein B1 | 0 | 0 | 1 | 1 |
| Tyrosine-protein phosphatase non-receptor type 1 | 0 | 1 | 0 | 1 |
| Corticosteroid 11-beta-dehydrogenase isozyme 1 | 0 | 1 | 1 | 2 |
| Corticosteroid 11-beta-dehydrogenase isozyme 1 | 0 | 1 | 1 | 2 |
| High mobility group protein B1 | 0 | 0 | 0 | 1 |
| Corticosteroid 11-beta-dehydrogenase isozyme 2 | 0 | 1 | 1 | 2 |
| Canalicular multispecific organic anion transporter 1 | 0 | 1 | 0 | 1 |
| Solute carrier organic anion transporter family member 1B3 | 0 | 1 | 0 | 1 |
| Solute carrier organic anion transporter family member 1B2 | 0 | 1 | 0 | 1 |
| Solute carrier organic anion transporter family member 1B1 | 0 | 1 | 0 | 1 |
| Chain A, Uracil Phosphoribosyltransferase | 0 | 0 | 1 | 1 |
| Chain B, Uracil Phosphoribosyltransferase | 0 | 0 | 1 | 1 |
| Chain C, Uracil Phosphoribosyltransferase | 0 | 0 | 1 | 1 |
| 2-dehydropantoate 2-reductase | 0 | 0 | 1 | 1 |
| Ras-related protein Rab-7a | 0 | 0 | 1 | 1 |
| 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9 | 0 | 2 | 0 | 2 |
| Chain A, AMINOPEPTIDASE | 0 | 1 | 0 | 1 |
| Chain A, AMINOPEPTIDASE | 0 | 1 | 0 | 1 |
| Chain A, Leucine Aminopeptidase | 0 | 1 | 0 | 1 |
| Alkaline phosphatase, tissue-nonspecific isozyme | 0 | 1 | 0 | 1 |
| Intestinal-type alkaline phosphatase | 0 | 1 | 0 | 1 |
| Large neutral amino acids transporter small subunit 1 | 0 | 1 | 0 | 1 |
| Proton-coupled amino acid transporter 1 | 0 | 1 | 0 | 2 |
| Phospholipase A-2-activating protein | 0 | 1 | 0 | 1 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | 2 | 0 | 0 | 2 |
| GLS protein | 1 | 0 | 0 | 1 |
| thioredoxin glutathione reductase | 1 | 0 | 0 | 1 |
| caspase 7, apoptosis-related cysteine protease | 1 | 0 | 0 | 1 |
| glucocerebrosidase | 1 | 0 | 0 | 1 |
| caspase-3 | 1 | 0 | 0 | 1 |
| Caspase-7 | 1 | 0 | 0 | 1 |
| caspase-3 | 1 | 0 | 0 | 1 |
| Large neutral amino acids transporter small subunit 1 | 0 | 1 | 0 | 1 |
| GALC protein | 1 | 0 | 0 | 1 |
| beta-2 adrenergic receptor | 1 | 0 | 0 | 1 |
| lysosomal alpha-glucosidase preproprotein | 1 | 0 | 0 | 1 |
| mu-type opioid receptor isoform MOR-1 | 0 | 0 | 1 | 1 |
| 5-hydroxytryptamine receptor 2A | 0 | 0 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-4 | 1 | 0 | 0 | 1 |
| Neuronal acetylcholine receptor subunit beta-2 | 1 | 0 | 0 | 1 |
| SMAD family member 2 | 2 | 0 | 0 | 2 |
| SMAD family member 3 | 2 | 0 | 0 | 2 |
| nuclear receptor subfamily 1, group I, member 2 | 1 | 0 | 0 | 1 |
| nuclear receptor ROR-gamma isoform 1 | 3 | 0 | 0 | 3 |
| Flavin reductase (NADPH) | 0 | 0 | 1 | 1 |
| Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR | 0 | 0 | 1 | 1 |
| Chain A, Cruzipain | 1 | 0 | 0 | 1 |
| acetylcholinesterase | 1 | 0 | 0 | 1 |
| vitamin D3 receptor isoform VDRA | 1 | 0 | 0 | 1 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | 1 | 0 | 0 | 1 |
| Retinol-binding protein 4 | 0 | 0 | 1 | 1 |
| Beta-lactoglobulin | 0 | 0 | 1 | 1 |
| Amyloid-beta precursor protein | 0 | 1 | 0 | 1 |
| Alpha-synuclein | 0 | 1 | 0 | 1 |
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 1 | 0 | 0 | 1 |
| Serine/threonine-protein kinase D3 | 0 | 0 | 1 | 1 |
| Protein kinase C gamma type | 0 | 1 | 1 | 2 |
| Protein kinase C beta type | 0 | 1 | 1 | 2 |
| Luciferin 4-monooxygenase | 0 | 0 | 1 | 1 |
| Protein kinase C alpha type | 0 | 1 | 1 | 2 |
| Beta-1 adrenergic receptor | 0 | 1 | 0 | 1 |
| Protein kinase C eta type | 0 | 0 | 1 | 1 |
| Protein kinase C iota type | 0 | 0 | 1 | 1 |
| Protein kinase C epsilon type | 0 | 1 | 1 | 2 |
| Protein kinase C theta type | 0 | 0 | 1 | 1 |
| Protein kinase C zeta type | 0 | 0 | 1 | 1 |
| Protein kinase C delta type | 0 | 1 | 1 | 2 |
| Serine/threonine-protein kinase D1 | 0 | 0 | 1 | 1 |
| Ras guanyl-releasing protein 3 | 0 | 0 | 1 | 1 |
| Chain A, Ferritin light chain | 1 | 0 | 0 | 1 |
| acid sphingomyelinase | 1 | 0 | 0 | 1 |
| HLA class I histocompatibility antigen, A alpha chain | 0 | 0 | 1 | 1 |
| Dipeptidyl peptidase 4 | 0 | 1 | 0 | 1 |
| Histamine H1 receptor | 0 | 0 | 1 | 1 |
| Adenosylhomocysteinase | 0 | 1 | 0 | 1 |
| RNA-directed RNA polymerase | 0 | 1 | 1 | 2 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |