Page last updated: 2024-09-27

Scleredema Adultorum

A diffuse, non-pitting induration of the skin of unknown etiology that occurs most commonly in association with diabetes mellitus, predominantly in females. It typically begins on the face or head and spreads to other areas of the body, sometimes involving noncutaneous tissues. Often it is preceded by any of various infections, notably staphylococcal infections. The condition resolves spontaneously, usually within two years of onset. (From Dorland, 27th ed)

Synonyms(1)

Synonym
Scleredema Adultorum

Research

Studies (65)

TimeframeStudies, This Condition (%)All Conditions %
pre-199043 (66.15)23.3326
1990's6 (9.23)12.5806
2000's3 (4.62)18.1394
2010's12 (18.46)28.8240
2020's1 (1.54)9.53
DrugIndicatedRelationship StrengthStudiesTrials
carnitine0low20
salicylic acid0low10
chlorpromazine0low10
dimercaprol0low20
hydroxychloroquine0low10
khellin0low30
procaine0low10
tolmetin0low10
prednisolone0low60
hydroxyproline0low10
prednisone0low30
ethinyl estradiol0low10
colchicine0low10
tryptophan0low10
vinyl chloride0low10
methylprednisolone0low20
penicillin v0low10
pyrazines0low10
d-alpha tocopherol0low50
tocopherols0low10
trolamine salicylate0low30
triamcinolone0low10
propiconazole0low10
methotrexate0low50
cortisone0low30
bortezomib0low20
glycogen0low10
inositol 3-phosphate0low10
pentazocine0low10
retinol0low10
melphalan0low10
bromochloroacetic acid0low20
unithiol0low20
tamoxifen0low10
dermatan sulfate0low10
alprostadil0low10
clobetasol0low20
chondroitin0low20
ascorbic acid0low10
hyaluronoglucosaminidase0low10
cyclosporine0low10
chondroitin sulfates0low20
allopurinol0low10
eye0low20

Protein Targets (802)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
interleukin 86006
TDP1 protein190019
AR protein260026
thyroid stimulating hormone receptor6006
estrogen receptor 2 (ER beta)140014
progesterone receptor180018
glucocorticoid receptor [Homo sapiens]220022
estrogen-related nuclear receptor alpha230023
estrogen nuclear receptor alpha260026
IDH1100010
euchromatic histone-lysine N-methyltransferase 2150015
Bloom syndrome protein isoform 14004
transcriptional regulator ERG isoform 33003
thyroid hormone receptor beta isoform 2160016
ras-related protein Rab-9A6006
nuclear factor erythroid 2-related factor 2 isoform 1220022
geminin180018
survival motor neuron protein isoform d7007
lamin isoform A-delta10150015
ATP-binding cassette sub-family C member 3017018
Multidrug resistance-associated protein 4017020
Polyphenol oxidase 20304
Voltage-dependent calcium channel gamma-2 subunit130013
Bile salt export pump022022
Hypoxanthine-guanine phosphoribosyltransferase0001
Cellular tumor antigen p53210021
Glutamate receptor 2130013
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase 0101
Adenosine receptor A2a0415
Xanthine dehydrogenase/oxidase0202
Nuclear receptor ROR-gamma0101
Xanthine dehydrogenase/oxidase0315
Purine nucleoside phosphorylase0011
TAR DNA-binding protein 437007
Canalicular multispecific organic anion transporter 1017017
Shiga toxin subunit A0101
Histamine H3 receptor0101
peroxisome proliferator activated receptor gamma170017
Thromboxane-A synthase 0303
Prostaglandin E2 receptor EP3 subtype0202
Prostaglandin E2 receptor EP4 subtype0213
Prostaglandin E2 receptor EP1 subtype0202
Prostacyclin receptor0112
Nuclear receptor subfamily 4 group A member 20011
Solute carrier organic anion transporter family member 2A10102
Nuclear receptor subfamily 4 group A member 20011
Nuclear receptor subfamily 4 group A member 20011
Prostaglandin E2 receptor EP2 subtype0213
Solute carrier organic anion transporter family member 2A10001
Solute carrier organic anion transporter family member 2B10101
Solute carrier organic anion transporter family member 3A10001
Chain A, Hyaluronidase, phage associated0101
acetylcholinesterase6006
RAR-related orphan receptor gamma200020
GLI family zinc finger 3170017
thioredoxin glutathione reductase8008
cytochrome P450 family 3 subfamily A polypeptide 4150015
retinoic acid nuclear receptor alpha variant 1190019
vitamin D (1,25- dihydroxyvitamin D3) receptor160016
chromobox protein homolog 1120012
nuclear factor erythroid 2-related factor 2 isoform 29009
lethal(3)malignant brain tumor-like protein 1 isoform I2002
lethal factor (plasmid)5005
Pancreatic alpha-amylase0202
Albumin0101
Urease0101
Prolyl 4-hydroxylase subunit alpha-10001
Tyrosinase0101
Alpha-2B adrenergic receptor0516
Spike glycoprotein71311
Hyaluronate lyase0101
Prolyl hydroxylase EGLN20001
Egl nine homolog 10001
Prolyl hydroxylase EGLN30001
Hypoxia-inducible factor 1-alpha inhibitor0001
Solute carrier family 23 member 10101
pregnane X receptor8008
farnesoid X nuclear receptor130013
pregnane X nuclear receptor170017
aryl hydrocarbon receptor120012
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a150015
nuclear receptor subfamily 1, group I, member 25005
thyroid hormone receptor beta isoform a7007
galanin receptor type 30101
Glucocorticoid receptor014221
Glycine receptor subunit alpha-1014014
Glycine receptor subunit beta014014
Glycine receptor subunit alpha-2014014
Glycine receptor subunit alpha-3014014
ORF730011
Chain H, Proteasome component PUP10101
Chain I, Proteasome component PUP30101
Chain K, Proteasome component PRE20101
Chain L, Proteasome component C50101
Chain K, Proteasome component PRE20101
Chain L, Proteasome component C50101
Proteasome subunit beta type-110102
Fumarate hydratase6006
PPM1D protein6006
caspase 7, apoptosis-related cysteine protease5005
nuclear receptor subfamily 1, group I, member 3140014
EWS/FLI fusion protein6006
retinoid X nuclear receptor alpha170017
polyprotein6006
peroxisome proliferator-activated receptor delta110011
caspase-35005
Histone H2A.x5005
Caspase-74004
caspase-34004
heat shock protein beta-19009
26S proteasome non-ATPase regulatory subunit 110101
26S proteasome non-ATPase regulatory subunit 120101
26S proteasome non-ATPase regulatory subunit 140101
Proteasome subunit alpha type-70102
Histone deacetylase 30101
26S proteasome non-ATPase regulatory subunit 30101
Carbonic anhydrase 120305
Prothrombin0202
Chymotrypsinogen A0101
Carbonic anhydrase 10507
Carbonic anhydrase 20518
Interferon beta140014
Carbonic anhydrase 30304
Cathepsin B0101
Neutrophil elastase0101
Cathepsin G0202
Lysosomal protective protein0101
Chymotrypsinogen B0101
26S proteasome regulatory subunit 6A0101
Nuclear factor NF-kappa-B p105 subunit0101
Proteasome subunit beta type-10103
Carbonic anhydrase 40406
Carbonic anhydrase 60305
Chymase0101
Proteasome subunit alpha type-10102
Proteasome subunit alpha type-20102
Proteasome subunit alpha type-30102
Proteasome subunit alpha type-40102
Proteasome subunit beta type-80102
Proteasome subunit beta type-80101
Proteasome subunit beta type-90102
Proteasome subunit alpha type-50102
Proteasome subunit beta type-40102
Proteasome subunit beta type-60102
Proteasome subunit beta type-50204
Carbonic anhydrase 5A, mitochondrial0305
26S proteasome regulatory subunit 70101
Lon protease homolog, mitochondrial0101
Proteasome subunit beta type-100102
Carbonic anhydrase 70305
26S proteasome regulatory subunit 6B0101
26S proteasome non-ATPase regulatory subunit 80101
Proteasome subunit beta type-30102
Proteasome subunit beta type-20103
26S proteasome non-ATPase regulatory subunit 70101
26S proteasome non-ATPase regulatory subunit 40101
26S proteasome complex subunit SEM10101
Proteasome subunit alpha type-60113
26S proteasome regulatory subunit 40101
26S proteasome regulatory subunit 80101
26S proteasome regulatory subunit 10B0101
Beta-carbonic anhydrase 10101
Nuclear factor NF-kappa-B p100 subunit 0101
Transcription factor p650101
26S proteasome non-ATPase regulatory subunit 20101
Histone deacetylase 10101
26S proteasome non-ATPase regulatory subunit 60101
Proteasomal ubiquitin receptor ADRM10101
Carbonic anhydrase 90305
ATP-dependent Clp protease proteolytic subunit0112
Carbonic anhydrase 130101
NACHT, LRR and PYD domains-containing protein 3 0101
Proteasome subunit alpha-type 80102
Histone deacetylase 20101
ATPase family AAA domain-containing protein 5110011
Proteasome subunit beta type-70102
26S proteasome non-ATPase regulatory subunit 10101
Ataxin-2120012
Carbonic anhydrase 150304
Histone deacetylase 80101
Histone deacetylase 60101
Carbonic anhydrase 140305
26S proteasome non-ATPase regulatory subunit 130101
Carbonic anhydrase 5B, mitochondrial0305
aldehyde dehydrogenase 1 family, member A19009
thyroid stimulating hormone receptor8008
Nuclear receptor ROR-gamma81110
Chain A, angiotensin converting enzyme0101
Chain A, angiotensin converting enzyme0101
Chain A, HADH2 protein5005
Chain B, HADH2 protein5005
Chain A, 2-oxoglutarate Oxygenase5005
15-lipoxygenase, partial4004
phosphopantetheinyl transferase8008
Microtubule-associated protein tau9009
Thrombopoietin3003
Metallo-beta-lactamase type 20112
peripheral myelin protein 22 isoform 15005
M-phase phosphoprotein 87007
transient receptor potential cation channel subfamily V member 11001
Renin0101
Neprilysin0101
Neprilysin0101
Leukotriene A-4 hydrolase0213
EEF1AKMT4-ECE2 readthrough transcript protein0101
Angiotensin-converting enzyme 0213
Angiotensin-converting enzyme0607
Leukotriene A-4 hydrolase0101
Thymidine phosphorylase0011
Prostaglandin G/H synthase 10505
Prostaglandin G/H synthase 20516
Endothelin-converting enzyme 10101
Succinyl-diaminopimelate desuccinylase0202
Angiotensin-converting enzyme0202
Solute carrier family 15 member 10202
Beta-lactamase TEM0101
Mu-type opioid receptor0011
Beta-lactamase 0203
Beta-lactamase 0202
Angiotensin-converting enzyme 2 0235
Beta-lactamase class B VIM-2 0112
ATP-dependent phosphofructokinase7007
Solute carrier family 22 member 50001
Solute carrier family 22 member 50001
Solute carrier family 22 member 160001
Solute carrier family 22 member 210001
Solute carrier family 22 member 50001
GALC protein2002
apical membrane antigen 1, AMA13003
Solute carrier family 22 member 60404
Multidrug resistance-associated protein 1 0103
Solute carrier family 15 member 10303
Solute carrier family 15 member 20202
Solute carrier family 22 member 60304
Solute carrier family 15 member 20101
Solute carrier family 22 member 80304
Solute carrier family 22 member 80101
Chain A, TYROSYL-DNA PHOSPHODIESTERASE5005
thioredoxin reductase110011
ATAD5 protein, partial5005
USP1 protein, partial9009
NFKB1 protein, partial2002
Smad35005
NADPH oxidase 10101
G8008
cytochrome P450 2D64004
67.9K protein7007
Snq2p0001
Adenylate cyclase type 1 0202
v-jun sarcoma virus 17 oncogene homolog (avian)9009
Spike glycoprotein0134
Replicase polyprotein 1ab0134
cytochrome P450 2D6 isoform 16006
cellular tumor antigen p53 isoform a5005
D(1A) dopamine receptor2002
vitamin D3 receptor isoform VDRA8008
potassium voltage-gated channel subfamily H member 2 isoform d3003
histone deacetylase 9 isoform 32002
mitogen-activated protein kinase 13003
atrial natriuretic peptide receptor 2 precursor2002
serine/threonine-protein kinase mTOR isoform 13003
DNA polymerase kappa isoform 13003
peripheral myelin protein 227007
cytochrome P450 3A4 isoform 1100010
histone acetyltransferase KAT2A isoform 15005
muscarinic acetylcholine receptor M14004
Gamma-aminobutyric acid receptor subunit pi100010
Solute carrier family 22 member 1 0101
Polyunsaturated fatty acid lipoxygenase ALOX15B3003
Transmembrane protease serine 20134
Glutamate receptor ionotropic, NMDA 2D0101
Transient receptor potential cation channel subfamily V member 10101
Glutamate receptor ionotropic, NMDA 3B0101
Voltage-dependent L-type calcium channel subunit alpha-1F0101
Bile salt export pump0606
5-hydroxytryptamine receptor 40404
Potassium channel subfamily K member 20101
Epidermal growth factor receptor0303
HLA class I histocompatibility antigen, B alpha chain 8008
Albumin0437
Albumin0011
Major prion protein0011
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10101
Receptor tyrosine-protein kinase erbB-20202
Major prion protein0011
Integrin beta-34004
Cytochrome P450 1A20213
Tyrosine-protein kinase Fyn0202
Procathepsin L0235
Aldo-keto reductase family 1 member B10606
Muscarinic acetylcholine receptor M20718
Muscarinic acetylcholine receptor M40505
ATP-dependent translocase ABCB106110
Muscarinic acetylcholine receptor M10304
Muscarinic acetylcholine receptor M30304
Muscarinic acetylcholine receptor M40304
Integrin alpha-IIb4004
5-hydroxytryptamine receptor 1A0101
5-hydroxytryptamine receptor 2C0203
Muscarinic acetylcholine receptor M50304
Muscarinic acetylcholine receptor M50606
Alpha-2A adrenergic receptor0505
Replicase polyprotein 1a0134
Replicase polyprotein 1ab0134
Replicase polyprotein 1ab0235
Cys-loop ligand-gated ion channel0101
Calmodulin-10213
Replicase polyprotein 1ab0437
Cytochrome P450 2D60213
Muscarinic acetylcholine receptor M20304
Muscarinic acetylcholine receptor M10628
Cytochrome P450 2C9 0505
Polyunsaturated fatty acid lipoxygenase ALOX150202
D(2) dopamine receptor0405
5-hydroxytryptamine receptor 2A0202
Gamma-aminobutyric acid receptor subunit beta-1100010
Alpha-1B adrenergic receptor0606
Sphingomyelin phosphodiesterase0101
Gamma-aminobutyric acid receptor subunit delta100010
Gamma-aminobutyric acid receptor subunit gamma-2100010
Alpha-2C adrenergic receptor0303
D0202
D(3) dopamine receptor0202
5-hydroxytryptamine receptor 1A0404
Alpha-2B adrenergic receptor0202
Gamma-aminobutyric acid receptor subunit alpha-5100010
Gamma-aminobutyric acid receptor subunit alpha-3100010
D(2) dopamine receptor0101
Muscarinic acetylcholine receptor M30505
Substance-K receptor0404
D(1A) dopamine receptor0405
D(4) dopamine receptor0405
D(1B) dopamine receptor0102
Adenylate cyclase type 30202
Alpha-2C adrenergic receptor0202
UDP-glucuronosyltransferase 1A40002
Alpha-2A adrenergic receptor0202
Gamma-aminobutyric acid receptor subunit gamma-1100010
Gamma-aminobutyric acid receptor subunit alpha-2100010
Alpha-1D adrenergic receptor0202
Sodium-dependent noradrenaline transporter 0606
Sodium-dependent dopamine transporter0303
Histamine H2 receptor0404
Alpha-1D adrenergic receptor0606
D(1B) dopamine receptor0202
Adenylate cyclase type 20202
Adenylate cyclase type 40202
5-hydroxytryptamine receptor 2A0404
5-hydroxytryptamine receptor 2C0404
Gamma-aminobutyric acid receptor subunit alpha-4100010
Gamma-aminobutyric acid receptor subunit gamma-3100010
5-hydroxytryptamine receptor 1B0404
Trypanothione reductase0202
Gamma-aminobutyric acid receptor subunit alpha-6100010
D(4) dopamine receptor0202
5-hydroxytryptamine receptor 2B0101
Histamine H1 receptor0112
Sodium-dependent serotonin transporter0606
Melanocortin receptor 40404
5-hydroxytryptamine receptor 7 0101
Melanocortin receptor 50404
Pleiotropic ABC efflux transporter of multiple drugs0102
5-hydroxytryptamine receptor 70101
Histamine H1 receptor0202
Mu-type opioid receptor0707
Glutamate receptor ionotropic, NMDA 1 0102
D(3) dopamine receptor0405
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 4 subunit alpha0101
Adenylate cyclase type 80202
Delta-type opioid receptor0404
Kappa-type opioid receptor0707
5-hydroxytryptamine receptor 2B0404
Melanocortin receptor 30404
Alpha-1A adrenergic receptor0606
Histamine H2 receptor6006
D(1A) dopamine receptor2002
5-hydroxytryptamine receptor 60404
5-hydroxytryptamine receptor 70101
Cytochrome P450 2J20404
Gastrin/cholecystokinin type B receptor0101
D(2) dopamine receptor0203
Calmodulin 0112
Gamma-aminobutyric acid receptor subunit alpha-1100010
Gamma-aminobutyric acid receptor subunit beta-3100010
Gamma-aminobutyric acid receptor subunit beta-2100010
Aldehyde oxidase 10101
Glutamate receptor ionotropic, NMDA 2A 0102
Glutamate receptor ionotropic, NMDA 2B0102
Glutamate receptor ionotropic, NMDA 2C0102
Sodium channel protein type 7 subunit alpha0101
Voltage-dependent L-type calcium channel subunit alpha-1D 0101
Sodium-dependent dopamine transporter 0606
Adenylate cyclase type 60202
Adenylate cyclase type 50202
Glutamate receptor ionotropic, NMDA 10101
Aldehyde oxidase0303
Potassium voltage-gated channel subfamily H member 20606
Glutamate receptor ionotropic, NMDA 2A0101
Glutamate receptor ionotropic, NMDA 2B0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Sodium channel protein type 5 subunit alpha0101
Glutamate receptor ionotropic, NMDA 2C0101
Sodium channel protein type 9 subunit alpha0101
Glutamate receptor ionotropic, NMDA 2D0102
Nuclear receptor subfamily 3 group C member 3 0404
Adenylyl cyclase 7 0202
Glutamate receptor ionotropic, NMDA 3A0101
Glutamate receptor ionotropic, NMDA 3B0102
GABA theta subunit100010
Inositol hexakisphosphate kinase 18008
D0101
Sodium channel protein type 2 subunit alpha0101
Sigma non-opioid intracellular receptor 10606
Gamma-aminobutyric acid receptor subunit epsilon100010
Sodium channel protein type 3 subunit alpha0101
Glutamate receptor ionotropic, NMDA 3A0102
Sodium channel protein type 11 subunit alpha0101
Sodium channel protein type 8 subunit alpha0101
Histamine H3 receptor0101
Sodium channel protein type 10 subunit alpha0101
cytochrome P450 2C9, partial8008
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE6006
Chain A, Beta-lactamase4004
Chain A, Ferritin light chain4004
Luciferase4004
endonuclease IV2002
PAX80002
hypoxia-inducible factor 1 alpha subunit7007
glucocerebrosidase4004
activating transcription factor 66006
nuclear receptor subfamily 0 group B member 10101
cytochrome P450 2C19 precursor3003
cytochrome P450 2C9 precursor3003
flap endonuclease 14004
steroidogenic factor 10101
muscleblind-like protein 1 isoform 14004
caspase-1 isoform alpha precursor2002
neuropeptide S receptor isoform A2002
Solute carrier family 22 member 30101
Tubulin alpha-1A chain0213
Tubulin beta chain0213
Plasma kallikrein0002
Tubulin beta-4A chain0225
ATP-dependent translocase ABCB10202
Tubulin beta chain0225
Cytochrome P450 3A40606
Tubulin alpha-3C chain0225
Serine/threonine-protein kinase pim-10101
ATP-dependent translocase ABCB10202
Tubulin alpha-1B chain0225
Tubulin alpha-4A chain0225
Tubulin beta-4B chain0225
Vesicular acetylcholine transporter0101
Tubulin beta-3 chain0225
Tubulin beta-2A chain0225
Tubulin polymerization-promoting protein0011
Tubulin beta-8 chain0225
Tubulin beta-2B chain0202
Tubulin alpha-3E chain0225
Tubulin alpha-1A chain0225
Similar to alpha-tubulin isoform 1 0101
Similar to alpha-tubulin isoform 1 0101
CREB-binding protein1001
Tubulin alpha-1C chain0225
Tubulin beta-6 chain0225
Tubulin beta-2B chain0225
Tubulin beta-1 chain0225
dopamine D1 receptor2002
GLS protein4004
regulator of G-protein signaling 44004
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a6006
atrial natriuretic peptide receptor 1 precursor1001
Sex hormone-binding globulin0022
Corticosteroid-binding globulin0202
Potassium voltage-gated channel subfamily A member 10011
Multidrug and toxin extrusion protein 10404
importin subunit beta-1 isoform 14004
snurportin-14004
GTP-binding nuclear protein Ran isoform 12002
Rap guanine nucleotide exchange factor 31001
Glutathione S-transferase P0101
Alpha-tocopherol transfer protein0011
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
Chain A, Cruzipain3003
SMAD family member 26006
SMAD family member 36006
STAT3, partial0101
alpha-galactosidase2002
NPC intracellular cholesterol transporter 1 precursor2002
tumor necrosis factor1001
parathyroid hormone/parathyroid hormone-related peptide receptor precursor3003
signal transducer and activator of transcription 1-alpha/beta isoform alpha0101
nuclear receptor ROR-gamma isoform 17007
Solute carrier organic anion transporter family member 1A40102
Sodium/potassium-transporting ATPase subunit alpha-1 0202
Sodium/potassium-transporting ATPase subunit beta-10202
Sodium/potassium-transporting ATPase subunit alpha-20101
Sodium/potassium-transporting ATPase subunit alpha-3 0101
Sodium/potassium-transporting ATPase subunit beta-1 0101
Sodium/potassium-transporting ATPase subunit alpha-30101
Sodium/potassium-transporting ATPase subunit beta-20101
Sodium/potassium-transporting ATPase subunit alpha-20202
Sodium/potassium-transporting ATPase subunit alpha-10101
Sodium/potassium-transporting ATPase subunit beta-30101
Sodium/potassium-transporting ATPase subunit gamma0101
Sodium/potassium-transporting ATPase subunit alpha-40101
Sodium/potassium-transporting ATPase subunit alpha-40101
Solute carrier organic anion transporter family member 4C10001
Solute carrier organic anion transporter family member 4C10001
Solute carrier organic anion transporter family member 1A40001
Solute carrier organic anion transporter family member 1B30304
Solute carrier organic anion transporter family member 1B10303
Nuclear receptor subfamily 1 group I member 20022
lysosomal alpha-glucosidase preproprotein1001
urokinase-type plasminogen activator precursor2002
plasminogen precursor2002
urokinase plasminogen activator surface receptor precursor2002
Vpr1001
Solute carrier family 22 member 20101
Cytochrome P450 2B10101
Estrogen receptor0629
Neuronal acetylcholine receptor subunit alpha-41102
Adenosine receptor A30404
Neuronal acetylcholine receptor subunit beta-21102
Androgen receptor0707
Cytochrome P450 2B60202
UDP-glucuronosyltransferase 1A1 0102
3-oxo-5-alpha-steroid 4-dehydrogenase 1 0101
Sulfotransferase 1A10214
Nuclear receptor subfamily 1 group I member 3 0101
Multidrug and toxin extrusion protein 20101
Estrogen receptor beta0527
thyrotropin-releasing hormone receptor2002
Glucose-6-phosphate 1-dehydrogenase0202
Serum paraoxonase/arylesterase 10202
Corticosteroid 11-beta-dehydrogenase isozyme 10101
Adenosine receptor A10101
Corticosteroid 11-beta-dehydrogenase isozyme 10101
6-phosphogluconate dehydrogenase, decarboxylating0202
Holo-[acyl-carrier-protein] synthase0101
Sodium/bile acid cotransporter0101
Carbonic anhydrase 130204
G-protein coupled receptor 350112
CDGSH iron-sulfur domain-containing protein 10202
Broad substrate specificity ATP-binding cassette transporter ABCG20203
Chain A, Type Iii Chloramphenicol Acetyltransferase0101
streptokinase A precursor0022
Estrogen receptor0023
Guanine nucleotide-binding protein G3003
Estrogen receptor beta0023
Canalicular multispecific organic anion transporter 10203
large T antigen0101
Genome polyprotein 0101
Sigma intracellular receptor 20202
Cyclic GMP-AMP synthase0101
Toll-like receptor 90101
Toll-like receptor 70101
Neutral amino acid transporter A0101
Asc-type amino acid transporter 10101
Neutral amino acid transporter B(0)0101
Proton-coupled amino acid transporter 10101
Amino acid transporter0101
Chain A, membrane-associated prostaglandin E synthase-20101
Chain A, Putative fructose-1,6-bisphosphate aldolase1001
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)6006
Parkin1001
bromodomain adjacent to zinc finger domain 2B5005
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)2002
DNA polymerase iota isoform a (long)5005
Prostaglandin-H2 D-isomerase0101
Prostaglandin E synthase0101
Prostaglandin G/H synthase 1 0102
Prostaglandin G/H synthase 2 0102
3',5'-cyclic-AMP phosphodiesterase 0101
Solute carrier organic anion transporter family member 2B1 0202
Cytochrome c oxidase subunit 20101
Phospholipase A2, major isoenzyme0101
Prostaglandin G/H synthase 10203
Interleukin-80202
Androgen receptor0213
Polyunsaturated fatty acid 5-lipoxygenase0102
Aldo-keto reductase family 1 member B10202
Aldo-keto reductase family 1 member B10101
Aldo-keto reductase family 1 member C40101
Prostaglandin G/H synthase 10101
Sodium- and chloride-dependent GABA transporter 10101
Adenosine receptor A10101
Indoleamine 2,3-dioxygenase 10101
Caspase-10001
Nitric oxide synthase, inducible0101
Adenosine receptor A2a0101
Substance-P receptor0202
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Bifunctional epoxide hydrolase 20101
Prostaglandin G/H synthase 2 0101
Peroxisome proliferator-activated receptor gamma0011
Aldo-keto reductase family 1 member C30202
Sodium- and chloride-dependent betaine transporter0101
C-X-C chemokine receptor type 30101
Aldo-keto reductase family 1 member C2 0101
Prostaglandin D2 receptor 0202
Solute carrier organic anion transporter family member 1A30102
Prostaglandin G/H synthase 20202
Lactoylglutathione lyase0202
Aldo-keto reductase family 1 member C10101
Prostaglandin G/H synthase 20102
Uracil nucleotide/cysteinyl leukotriene receptor0202
Solute carrier family 22 member 70002
Sigma intracellular receptor 20202
Rho-associated protein kinase 20101
Prostaglandin G/H synthase 1 0101
Nicotinate phosphoribosyltransferase0202
Dehydrogenase/reductase SDR family member 90101
P2Y purinoceptor 120101
Cytosolic phospholipase A2 gamma0101
Prostaglandin D2 receptor 20112
Carbonic anhydrase0102
glp-1 receptor, partial4004
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 13003
Cytochrome P450 1A10202
Cytochrome P450 2C190101
Cytochrome P450 1B10101
Large neutral amino acids transporter small subunit 1 0101
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
acid sphingomyelinase1001
ClpP1001
Thymidylate synthase 0101
Thymidylate synthase 0101
polyunsaturated fatty acid lipoxygenase ALOX121001
DNA polymerase beta1001
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0101
peptidyl-prolyl cis-trans isomerase NIMA-interacting 12002
DNA polymerase eta isoform 11001
transactivating tegument protein VP16 [Human herpesvirus 1]0101
nuclear receptor coactivator 3 isoform a0101
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0405
Dihydrofolate reductase0203
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Tyrosine-protein kinase ABL10011
Thymidylate synthase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Thymidylate synthase0202
High mobility group protein B10022
Dihydrofolate reductase0101
Thymidylate synthase0101
Dihydrofolate reductase0224
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0101
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Dihydrofolate reductase0202
Histidine decarboxylase0101
Trifunctional purine biosynthetic protein adenosine-30101
Cyclin-dependent kinase 20011
Bifunctional purine biosynthesis protein ATIC0202
Delta-type opioid receptor0101
Mu-type opioid receptor0101
Kappa-type opioid receptor0101
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
Caspase-71001
Dihydrofolate reductase0101
Pteridine reductase 10101
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Trifunctional purine biosynthetic protein adenosine-30101
Solute carrier family 22 member 200202
Dihydrofolate reductase 0101
Solute carrier family 22 member 60202
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Multidrug resistance associated protein0102
Solute carrier family 22 member 110001
Protein-arginine deiminase type-40101
nonstructural protein 12002
Nuclear receptor subfamily 1 group I member 20011
Solute carrier family 22 member 80101
Beta-lactamase OXA-70001
Sigma non-opioid intracellular receptor 10101
Chain A, JmjC domain-containing histone demethylation protein 3A2002
serine-protein kinase ATM isoform a1001
arylsulfatase A4004
Cytochrome P450 2A60112
Muscarinic acetylcholine receptor M10011
Muscarinic acetylcholine receptor DM10101
Cytochrome P450 2A130112
luciferase0001
Fatty acid-binding protein, liver0101
Progesterone receptor0304
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Mineralocorticoid receptor 0213
Glutamine synthetase0011
Nociceptin receptor0011
heat shock protein HSP 90-alpha isoform 20001
heat shock protein 90, putative0001
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR0011
ubiquitin carboxyl-terminal hydrolase 2 isoform a1001
Retinol-binding protein 40011
Beta-lactoglobulin0011
Amyloid-beta precursor protein0101
Alpha-synuclein1102
Disintegrin and metalloproteinase domain-containing protein 171001
chaperonin-containing TCP-1 beta subunit homolog1001
Estrogen receptor beta0001
Inhibitor of nuclear factor kappa-B kinase subunit beta0001
5'-AMP-activated protein kinase subunit beta-20001
Polymerase acidic protein0011
Stromelysin-10112
Tyrosine-protein phosphatase YopH0101
Prolyl 4-hydroxylase subunit alpha-10101
Tyrosine-protein phosphatase non-receptor type 10103
Estrogen receptor0001
Acetylcholinesterase0101
Cystathionine gamma-lyase0101
5'-AMP-activated protein kinase subunit gamma-10001
5'-AMP-activated protein kinase catalytic subunit alpha-20001
5'-AMP-activated protein kinase catalytic subunit alpha-10001
Carbonic anhydrase0101
Ubiquitin-like domain-containing CTD phosphatase 10101
5'-AMP-activated protein kinase subunit gamma-30001
5'-AMP-activated protein kinase subunit gamma-20001
5'-AMP-activated protein kinase subunit beta-10001
Chain A, CES1 protein0101
DNA polymerase III, partial1001
interferon gamma precursor0001
ubiquitin-conjugating enzyme E2 N0101
Serine/threonine-protein kinase D30101
Lysosomal acid glucosylceramidase0011
Protein kinase C gamma type0101
Protein kinase C alpha type0101
Protein kinase C beta type0101
Tyrosine-protein kinase Lck0101
Beta-1 adrenergic receptor0202
Protein kinase C delta type0101
Protein kinase C epsilon type0101
Protein kinase C zeta type0101
Polyunsaturated fatty acid 5-lipoxygenase0101
Steroid hormone receptor ERR10101
Transcriptional activator protein LuxR0101
Beta-3 adrenergic receptor0202
Protein kinase C alpha type0101
Protein kinase C eta type0101
Substance-P receptor0202
B2 bradykinin receptor0202
Adenosine receptor A10202
C-8 sterol isomerase0101
Protein kinase C iota type0101
Estrogen-related receptor gamma0101
Protein kinase C gamma type0101
Protein kinase C beta type0101
Phospholipase D1 0101
Protein kinase C epsilon type0101
Protein kinase C theta type0101
Protein kinase C zeta type0101
Protein kinase C delta type0101
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform0101
Platelet-activating factor acetylhydrolase0101
Phospholipase D10101
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0213
Serine/threonine-protein kinase D10101
Protein kinase C eta type0101
Emopamil-binding protein-like0101
7-dehydrocholesterol reductase0112
Protein kinase C theta type0101
procathepsin L isoform 1 preproprotein0101
Chain A, Trp Rna-binding Attenuation Protein0011
Chain K, Trp Rna-binding Attenuation Protein0011
Chain B, tryptophanyl-tRNA synthetase0011
Chain C, Tryptophanyl-tRNA synthetase II0011
histone-lysine N-methyltransferase 2A isoform 2 precursor1001
Myeloperoxidase0101
Alkaline phosphatase, tissue-nonspecific isozyme0101
Intestinal-type alkaline phosphatase0101
Indoleamine 2,3-dioxygenase 10102
Tryptophan 2,3-dioxygenase0102
Carbonic anhydrase0001
Large neutral amino acids transporter small subunit 10101
SLC16A10 protein0001
Carbonic anhydrase 0001
Carbonic anhydrase-like protein, putative0001
Tryprostatin B synthase0001
Carbonic anhydrase0001
Carbonic anhydrase0001
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase0011
Carbonic anhydrase 0001
Monocarboxylate transporter 100001
Phospholipase A-2-activating protein0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]