Ritter Disease

A disease of infants due to group 2 phage type 17 staphylococci that produce an epidermolytic exotoxin. Superficial fine vesicles and bullae form and rupture easily, resulting in loss of large sheets of epidermis.

Synonym
Staphylococcal Scalded Skin Syndrome
Staphylococcal Scalded-Skin Syndrome
Ritter's Disease
Ritter Disease
Scalded Skin Syndrome, Staphylococcal

Excerpt	Reference
"Staphylococcal scalded skin syndrome is a clinical term used for a spectrum of primarily neonatal blistering skin disorders caused by the exfoliative toxins of Staphylococcus aureus."	( Bhutta, ZA; Ladhani, S, 1998)
"Staphylococcal scalded skin syndrome is the term used for a spectrum of primarily neonatal blistering skin diseases caused by the exfoliative toxins, ETA and ETB, of Staphylococcus aureus."	( Evans, RW; Joannou, CL; Ladhani, S; Poston, SM, 1999)
"Staphylococcal scalded skin syndrome is a toxin mediated Staphylococcal infection, the toxin produced by staphylococcus aureus type 2 phage types (55,71,3A,3B,3C)."	( Al-Gadi, MA; Mohammed, AA, 2003)
"Staphylococcal scalded skin syndrome is an exfoliating skin disease which primarily affects children."	( De Vries, A; Haasnoot, PJ, 2018)

Excerpt	Reference
"We report a case of staphylococcal scalded skin syndrome (SSSS) in a 5-year-old girl who had been hospitalized for burn treatment."	( Koga, M; Oh-i, T; Oyake, S, 2001)
"This case report highlights staphylococcal scalded skin syndrome and its treatment, and future challenges."	( De Vries, A; Haasnoot, PJ, 2018)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	13 (16.88)	23.3326
1990's	14 (18.18)	12.5806
2000's	28 (36.36)	18.1394
2010's	14 (18.18)	28.8240
2020's	8 (10.39)	9.53

Drug	Relationship Strength	Studies	Trials
adenine	low	1	0
beta-alanine	medium	1	1
acetaminophen	low	1	0
cefuroxime	low	1	0
gentamicin	low	4	0
hexachlorophene	low	1	0
hydroxychloroquine	low	1	0
indomethacin	low	1	0
isoniazid	low	1	0
leflunomide	low	1	0
pyrimethamine	low	1	0
prednisone	low	3	0
serine	low	1	0
methicillin	low	3	0
cloxacillin	low	3	0
colchicine	low	1	0
oxacillin	low	2	0
nafcillin	low	2	0
isoxazoles	low	1	0
erythromycin	low	2	0
vancomycin	low	6	0
methylprednisolone hemisuccinate	low	1	0
sulfadoxine	low	1	0
dicloxacillin	low	1	0
floxacillin	low	10	0
glutamic acid	low	2	0
fanasil, pyrimethamine drug combination	low	1	0
cephalosporin c	low	5	0
flomoxef	low	1	0
delphinidin	low	1	0
arbekacin	low	2	0
oxazolidin-2-one	low	1	0
panipenem-betamipron	medium	1	1
trimethoprim, sulfamethoxazole drug combination	low	1	0
netilmicin	low	1	0
linezolid	low	1	0
clindamycin phosphate	low	1	0
retinol	low	1	0
mupirocin	low	3	0
clindamycin	low	8	0
dibekacin	low	2	0
sodium bicarbonate	low	1	0
bromochloroacetic acid	low	1	0
fusidic acid	low	3	0
vitamin k semiquinone radical	low	1	0
miocamycin	low	1	0
rokitamycin	low	1	0
phenylephrine hydrochloride	low	4	0
morphine	low	2	0
hr 810	low	1	0
cefotaxime	low	1	0
cefpodoxime proxetil	low	1	0
amoxicillin-potassium clavulanate combination	low	1	0
thiocolchicoside	low	1	0
rifamycins	low	1	0
pci 32765	low	1	0
piperidines	low	1	0
oxytetracycline, anhydrous	low	1	0
calca protein, human	low	1	0
caseins	low	1	0
acyclovir	low	1	0

Protein Targets (1,120)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
RAR-related orphan receptor gamma	12	0	0	12
ATAD5 protein, partial	4	0	0	4
GLS protein	6	0	0	6
Microtubule-associated protein tau	6	0	0	6
Smad3	6	0	0	6
aldehyde dehydrogenase 1 family, member A1	7	0	0	7
thyroid stimulating hormone receptor	7	0	0	7
nuclear receptor subfamily 1, group I, member 3	10	0	0	10
progesterone receptor	8	0	0	8
EWS/FLI fusion protein	9	0	0	9
retinoic acid nuclear receptor alpha variant 1	10	0	0	10
retinoid X nuclear receptor alpha	7	0	0	7
estrogen-related nuclear receptor alpha	13	0	0	13
estrogen nuclear receptor alpha	20	0	0	20
peroxisome proliferator activated receptor gamma	8	0	0	8
aryl hydrocarbon receptor	7	0	0	7
chromobox protein homolog 1	6	0	0	6
thyroid hormone receptor beta isoform 2	12	0	0	12
peripheral myelin protein 22	10	0	0	10
cytochrome P450 3A4 isoform 1	8	0	0	8
Gamma-aminobutyric acid receptor subunit pi	8	0	0	8
ATP-binding cassette sub-family C member 3	0	15	0	15
Multidrug resistance-associated protein 4	0	15	0	15
Solute carrier family 22 member 6	0	5	0	6
Carbonic anhydrase 12	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	0	0	1
Bile salt export pump	0	11	0	11
Voltage-dependent calcium channel gamma-2 subunit	8	0	0	8
Bile salt export pump	0	22	0	22
Cytochrome P450 2B1	0	0	0	1
Cytochrome P450 1A1	0	0	0	1
Carbonic anhydrase 1	0	2	0	3
Carbonic anhydrase 2	0	2	0	3
Myoglobin	0	1	0	1
Cytochrome P450 1A1	0	0	1	2
Cytochrome P450 1A2	0	5	0	7
Prostaglandin G/H synthase 1	0	3	0	4
Carbonic anhydrase 3	0	1	0	1
Cytochrome P450 3A4	0	9	1	12
Cytochrome P450 2D6	0	4	0	5
Cytochrome P450 2C9	0	8	0	10
Polyunsaturated fatty acid lipoxygenase ALOX15	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	8	0	0	8
Sulfotransferase 1A1	0	0	0	1
Gamma-aminobutyric acid receptor subunit delta	8	0	0	8
Gamma-aminobutyric acid receptor subunit gamma-2	8	0	0	8
UDP-glucuronosyltransferase 1-6	0	0	0	1
Glutamate receptor 2	8	2	1	11
Gamma-aminobutyric acid receptor subunit alpha-5	8	0	0	8
Gamma-aminobutyric acid receptor subunit alpha-3	8	0	0	8
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	0	0	1
Carbonic anhydrase 4	0	2	0	2
Prostaglandin G/H synthase 1	0	3	0	3
Carbonic anhydrase 6	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	8	0	0	8
Gamma-aminobutyric acid receptor subunit alpha-2	8	0	0	8
Gamma-aminobutyric acid receptor subunit alpha-4	8	0	0	8
Gamma-aminobutyric acid receptor subunit gamma-3	8	0	0	8
Gamma-aminobutyric acid receptor subunit alpha-6	8	0	0	8
Carbonic anhydrase 5A, mitochondrial	0	2	0	2
Prostaglandin G/H synthase 2	0	4	1	6
Carbonic anhydrase 7	0	1	0	1
Nuclear receptor ROR-gamma	8	0	0	8
Cytochrome P450 2J2	0	5	0	5
Gamma-aminobutyric acid receptor subunit alpha-1	8	0	0	8
Gamma-aminobutyric acid receptor subunit beta-3	8	0	0	8
Gamma-aminobutyric acid receptor subunit beta-2	8	0	0	8
Carbonic anhydrase 9	0	2	0	2
GABA theta subunit	8	0	0	8
Canalicular multispecific organic anion transporter 1	0	15	0	15
Carbonic anhydrase 15	0	1	0	1
Carbonic anhydrase 13	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	8	0	0	8
Carbonic anhydrase 14	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	2	0	2
toxin B	0	0	0	1
Chain E, Purine nucleoside phosphorylase	0	1	0	1
Chain A, HADH2 protein	3	0	0	3
Chain B, HADH2 protein	3	0	0	3
Chain A, ATP-DEPENDENT DNA HELICASE Q1	3	0	0	3
Chain A, Ferritin light chain	4	0	0	4
Thymidine kinase	0	1	0	1
thioredoxin reductase	9	0	0	9
phosphopantetheinyl transferase	10	0	0	10
TDP1 protein	17	0	0	17
arylsulfatase A	3	0	0	3
euchromatic histone-lysine N-methyltransferase 2	11	0	0	11
activating transcription factor 6	4	0	0	4
Histone H2A.x	4	0	0	4
Bloom syndrome protein isoform 1	4	0	0	4
hemoglobin subunit beta	1	0	0	1
atrial natriuretic peptide receptor 1 precursor	1	0	0	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	4	0	0	4
lamin isoform A-delta10	11	0	0	11
Solute carrier family 22 member 1	0	4	0	5
Purine nucleoside phosphorylase	0	3	0	3
Thymidine kinase, cytosolic	0	0	0	1
POU domain, class 2, transcription factor 2	0	0	0	1
Disintegrin and metalloproteinase domain-containing protein 17	2	0	0	2
Purine nucleoside phosphorylase	0	0	1	1
Solute carrier family 22 member 6	0	3	0	4
Thymidine kinase	0	1	0	1
Solute carrier family 22 member 8	0	4	0	6
Thymidine kinase	0	1	0	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	7	0	0	7
Chain A, MTA/SAH nucleosidase	0	1	0	1
Chain A, Ribosome-inactivating protein alpha-trichosanthin	0	0	1	1
Chain A, Ricin A chain	0	0	1	1
Chain A, Ribosome-inactivating protein 3	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
AR protein	18	0	0	18
cytochrome P450 family 3 subfamily A polypeptide 4	9	0	0	9
glucocorticoid receptor [Homo sapiens]	12	0	0	12
pregnane X nuclear receptor	10	0	0	10
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	9	0	0	9
nuclear factor erythroid 2-related factor 2 isoform 2	7	0	0	7
heat shock protein beta-1	5	0	0	5
importin subunit beta-1 isoform 1	2	0	0	2
snurportin-1	2	0	0	2
tumor susceptibility gene 101 protein	1	0	0	1
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
Cyclin-dependent kinase 1	0	1	1	2
Heat shock protein HSP 90-beta	0	1	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
TAR DNA-binding protein 43	3	0	0	3
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Leucine-rich repeat serine/threonine-protein kinase 2	0	2	0	2
ATPase family AAA domain-containing protein 5	7	0	0	7
Ataxin-2	7	0	0	7
regulator of G-protein signaling 4	3	0	0	3
lethal factor (plasmid)	4	0	0	4
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	3	1	4
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	3	1	4
Glutamate receptor ionotropic, NMDA 2B	0	3	1	4
Glutamate receptor ionotropic, NMDA 2C	0	3	1	4
Glutamate receptor ionotropic, NMDA 2D	0	3	1	4
Proton-coupled amino acid transporter 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 3B	0	3	1	4
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	3	1	4
thyroid stimulating hormone receptor	6	0	0	6
nuclear factor erythroid 2-related factor 2 isoform 1	12	0	0	12
Cellular tumor antigen p53	12	0	0	12
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	3
Beta-lactamase	0	1	0	3
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	3
Beta-lactamase	0	1	0	3
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase type 2	0	0	0	2
Metallo-beta-lactamase VIM-11	0	0	0	3
Metallo-beta-lactamase VIM-2	0	0	0	3
Metallo-beta-lactamase VIM-19	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	3
Metallo-beta-lactamase	0	0	0	2
Beta-lactamase	0	1	0	3
Beta-lactamase	0	0	0	1
Solute carrier family 22 member 5	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase SHV-1	0	0	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	2
Kappa-type opioid receptor	0	2	0	5
Solute carrier family 15 member 1	0	7	0	7
Beta-lactamase TEM	0	1	0	2
Beta-lactamase	0	0	0	1
B2 metallo-beta-lactamase	0	0	0	2
Solute carrier family 15 member 2	0	5	0	5
Metallo-beta-lactamase VIM-13	0	0	0	2
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase VIM-2	0	0	0	2
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase	0	0	0	2
Solute carrier family 15 member 2	0	6	0	6
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-b-lactamase	0	0	0	3
BlaVIM-1	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase class B VIM-2	0	0	0	3
Beta-lactamase VIM-1	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Albumin	0	1	6	7
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase Toho-1	0	0	0	1
Solute carrier family 22 member 7	0	1	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	1
Histamine H3 receptor	0	0	0	1
Solute carrier family 22 member 11	0	2	0	2
Solute carrier family 22 member 8	0	3	0	3
Solute carrier family 22 member 7	0	1	0	1
apical membrane antigen 1, AMA1	2	0	0	2
geminin	16	0	0	16
streptokinase A precursor	0	0	7	7
interleukin 8	5	0	0	5
G	5	0	0	5
cytochrome P450 2D6	5	0	0	5
vitamin D (1,25- dihydroxyvitamin D3) receptor	9	0	0	9
alpha-galactosidase	1	0	0	1
cytochrome P450 2C19 precursor	3	0	0	3
DNA polymerase kappa isoform 1	4	0	0	4
survival motor neuron protein isoform d	4	0	0	4
M-phase phosphoprotein 8	2	0	0	2
muscarinic acetylcholine receptor M1	4	0	0	4
Solute carrier family 22 member 1	0	2	0	2
Solute carrier family 22 member 2	0	2	0	3
Solute carrier family 22 member 2	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
Interferon beta	9	0	0	9
HLA class I histocompatibility antigen, B alpha chain	5	0	0	5
ATP-dependent translocase ABCB1	0	5	0	5
ATP-dependent translocase ABCB1	0	6	0	7
Potassium-transporting ATPase alpha chain 1	0	1	0	1
ATP-dependent translocase ABCB1	0	5	0	5
Histamine H2 receptor	0	2	0	2
Histamine H1 receptor	0	0	2	2
Histamine H2 receptor	5	2	1	8
Potassium-transporting ATPase subunit beta	0	1	0	1
Aldehyde oxidase	0	1	0	1
Solute carrier family 22 member 1	0	2	0	2
Multidrug and toxin extrusion protein 2	0	1	0	1
Inositol hexakisphosphate kinase 1	5	0	0	5
Multidrug and toxin extrusion protein 1	0	3	0	3
Histamine H4 receptor	0	1	0	1
Solute carrier family 22 member 2	0	2	0	2
Solute carrier family 22 member 4	0	1	0	1
cytochrome P450 2C9, partial	5	0	0	5
ATP-dependent phosphofructokinase	2	0	0	2
Protein-arginine deiminase type-4	0	2	0	2
Serum paraoxonase/arylesterase 1	0	3	0	3
Tyrosyl-DNA phosphodiesterase 1	0	2	0	2
Solute carrier family 22 member 8	0	5	0	5
Beta-lactamase OXA-7	0	0	0	3
Efflux transporter	0	1	0	1
Beta-lactamase	0	1	0	1
Chain A, Beta-lactamase	4	0	0	4
Luciferase	6	0	0	6
endonuclease IV	1	0	0	1
PAX8	0	0	0	2
pregnane X receptor	5	0	0	5
hypoxia-inducible factor 1 alpha subunit	5	0	0	5
Fumarate hydratase	5	0	0	5
USP1 protein, partial	6	0	0	6
PPM1D protein	3	0	0	3
GLI family zinc finger 3	10	0	0	10
Thrombopoietin	2	0	0	2
estrogen receptor 2 (ER beta)	6	0	0	6
farnesoid X nuclear receptor	5	0	0	5
polyprotein	5	0	0	5
67.9K protein	6	0	0	6
glucocerebrosidase	2	0	0	2
peroxisome proliferator-activated receptor delta	7	0	0	7
IDH1	6	0	0	6
v-jun sarcoma virus 17 oncogene homolog (avian)	7	0	0	7
nuclear receptor subfamily 1, group I, member 2	4	0	0	4
cytochrome P450 2D6 isoform 1	4	0	0	4
nuclear receptor subfamily 0 group B member 1	0	1	0	1
cellular tumor antigen p53 isoform a	3	0	0	3
cytochrome P450 2C9 precursor	3	0	0	3
thyroid hormone receptor beta isoform a	5	0	0	5
atrial natriuretic peptide receptor 2 precursor	1	0	0	1
flap endonuclease 1	3	0	0	3
ras-related protein Rab-9A	3	0	0	3
steroidogenic factor 1	0	1	0	1
muscleblind-like protein 1 isoform 1	2	0	0	2
caspase-1 isoform alpha precursor	1	0	0	1
neuropeptide S receptor isoform A	3	0	0	3
Solute carrier family 22 member 3	0	2	0	2
Tubulin alpha-1A chain	0	2	1	3
Tubulin beta chain	0	2	1	3
Plasma kallikrein	0	0	0	1
Tubulin beta-4A chain	0	2	2	5
Tubulin beta chain	0	2	2	5
Tubulin alpha-3C chain	0	2	2	5
Serine/threonine-protein kinase pim-1	0	1	1	2
Tubulin alpha-1B chain	0	2	2	5
Tubulin alpha-4A chain	0	2	2	5
Tubulin beta-4B chain	0	2	2	5
Vesicular acetylcholine transporter	0	1	0	1
Tubulin beta-3 chain	0	2	2	5
Tubulin beta-2A chain	0	2	2	5
Tubulin polymerization-promoting protein	0	0	1	1
Tubulin beta-8 chain	0	2	2	5
Tubulin beta-2B chain	0	2	0	2
Tubulin alpha-3E chain	0	2	2	5
Tubulin alpha-1A chain	0	2	2	5
Similar to alpha-tubulin isoform 1	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
CREB-binding protein	1	1	0	2
Tubulin alpha-1C chain	0	2	2	5
Tubulin beta-6 chain	0	2	2	5
Tubulin beta-2B chain	0	2	2	5
Tubulin beta-1 chain	0	2	2	5
Epidermal growth factor receptor	0	5	2	7
Vascular endothelial growth factor receptor 2	0	1	0	1
Alpha-synuclein	1	3	0	4
Lactoylglutathione lyase	0	2	0	2
Histone acetyltransferase p300	0	1	0	1
Motilin receptor	0	0	1	1
acid sphingomyelinase	1	0	0	1
low molecular weight phosphotyrosine protein phosphatase isoform c	0	2	0	2
serine/threonine-protein kinase PLK1	3	0	0	3
Motilin receptor	0	1	1	2
Rap guanine nucleotide exchange factor 3	4	0	0	4
30S ribosomal protein S6	0	3	1	4
30S ribosomal protein S7	0	3	1	4
50S ribosomal protein L15	0	3	1	4
60 kDa chaperonin	0	2	0	2
50S ribosomal protein L10	0	3	1	4
50S ribosomal protein L11	0	3	1	4
50S ribosomal protein L7/L12	0	3	1	4
50S ribosomal protein L19	0	3	1	4
50S ribosomal protein L1	0	3	1	4
50S ribosomal protein L20	0	3	1	4
50S ribosomal protein L27	0	3	1	4
50S ribosomal protein L28	0	3	1	4
50S ribosomal protein L29	0	3	1	4
50S ribosomal protein L31	0	3	1	4
50S ribosomal protein L31 type B	0	3	1	4
50S ribosomal protein L32	0	3	1	4
50S ribosomal protein L33	0	3	1	4
50S ribosomal protein L34	0	3	1	4
50S ribosomal protein L35	0	3	1	4
50S ribosomal protein L36	0	3	1	4
30S ribosomal protein S10	0	3	1	4
30S ribosomal protein S11	0	3	1	4
30S ribosomal protein S12	0	3	1	4
30S ribosomal protein S13	0	3	1	4
30S ribosomal protein S16	0	3	1	4
30S ribosomal protein S18	0	3	1	4
30S ribosomal protein S19	0	3	1	4
30S ribosomal protein S20	0	3	1	4
30S ribosomal protein S2	0	3	1	4
30S ribosomal protein S3	0	3	1	4
30S ribosomal protein S4	0	3	1	4
30S ribosomal protein S5	0	3	1	4
30S ribosomal protein S8	0	3	1	4
30S ribosomal protein S9	0	3	1	4
50S ribosomal protein L13	0	3	1	4
50S ribosomal protein L14	0	3	1	4
50S ribosomal protein L16	0	3	1	4
50S ribosomal protein L23	0	3	1	4
30S ribosomal protein S15	0	3	1	4
50S ribosomal protein L17	0	3	1	4
50S ribosomal protein L21	0	3	1	4
50S ribosomal protein L30	0	3	1	4
50S ribosomal protein L6	0	3	1	4
30S ribosomal protein S14	0	3	1	4
30S ribosomal protein S17	0	3	1	4
30S ribosomal protein S1	0	3	1	4
50S ribosomal protein L18	0	3	1	4
60 kDa heat shock protein, mitochondrial	0	4	0	4
Chitinase B	0	1	0	1
Low molecular weight phosphotyrosine protein phosphatase	0	2	0	2
50S ribosomal protein L2	0	3	1	4
50S ribosomal protein L3	0	3	1	4
50S ribosomal protein L24	0	3	1	4
50S ribosomal protein L4	0	3	1	4
50S ribosomal protein L22	0	3	1	4
10 kDa heat shock protein, mitochondrial	0	4	0	4
50S ribosomal protein L5	0	3	1	4
30S ribosomal protein S21	0	3	1	4
50S ribosomal protein L25	0	3	1	4
Potassium voltage-gated channel subfamily H member 2	0	6	0	6
Cytochrome P450 1B1	0	1	0	1
Thiosulfate sulfurtransferase	0	4	0	4
Lanosterol 14-alpha demethylase	0	2	0	2
50S ribosomal protein L36 2	0	3	1	4
60 kDa chaperonin	0	4	0	4
10 kDa chaperonin	0	4	0	4
Chain A, Type Iii Chloramphenicol Acetyltransferase	0	1	0	1
thioredoxin glutathione reductase	4	0	0	4
vitamin D3 receptor isoform VDRA	9	0	0	9
Estrogen receptor	0	0	5	5
Guanine nucleotide-binding protein G	2	0	0	2
Estrogen receptor beta	0	0	5	5
Canalicular multispecific organic anion transporter 1	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	2	0	2
large T antigen	0	2	0	2
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
glp-1 receptor, partial	5	0	0	5
beta-2 adrenergic receptor	2	0	0	2
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	2	0	0	2
Metabotropic glutamate receptor 8	0	2	0	2
Metabotropic glutamate receptor 6	0	1	1	3
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Excitatory amino acid transporter 4	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Glutathione reductase, mitochondrial	0	2	0	2
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
Prothrombin	0	0	1	1
Integrin beta-3	2	0	1	3
Integrin alpha-IIb	2	0	1	3
ATP-citrate synthase	0	1	0	1
Glutamate receptor 1	0	2	1	3
Glutamate receptor 3	0	2	1	3
Glutamate receptor 4	0	2	1	3
Glutamate receptor ionotropic, kainate 1	0	2	1	3
Metabotropic glutamate receptor 1	0	1	1	2
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 5	0	0	1	1
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Glutamate receptor ionotropic, kainate 1	0	1	1	2
Metabotropic glutamate receptor 5	0	1	1	3
Glutamate receptor ionotropic, kainate 2	0	2	1	3
Glutamate receptor 1	0	2	1	3
Glutamate receptor 2	0	2	1	3
Glutamate receptor 3	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	2	0	2
Excitatory amino acid transporter 1	0	2	0	3
Excitatory amino acid transporter 2	0	2	0	3
Excitatory amino acid transporter 3	0	2	0	3
Metabotropic glutamate receptor 8	0	0	1	1
Glutamate receptor 4	0	2	1	3
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Fatty-acid amide hydrolase 1	0	1	0	1
Glutamate receptor ionotropic, kainate 4	0	2	0	2
Glutamate carboxypeptidase 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	1	0	1
Glutamate receptor ionotropic, kainate 2	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	1	0	1
Metabotropic glutamate receptor 1	0	1	1	3
Metabotropic glutamate receptor 2	0	1	1	3
Metabotropic glutamate receptor 7	0	1	1	3
Metabotropic glutamate receptor 3	0	1	1	3
Metabotropic glutamate receptor 4	0	1	1	3
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Glutamate receptor ionotropic, kainate 5	0	1	0	1
Carbonic anhydrase-like protein, putative	0	0	0	1
Glutamate receptor ionotropic, kainate 5	0	2	0	2
Glutamate racemase	0	0	0	1
Prolyl 4-hydroxylase	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	1
Ricin	0	1	0	1
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	0	0	1	1
Purine nucleoside phosphorylase	0	0	1	2
Shiga toxin subunit A	0	1	0	1
Guanine deaminase	0	0	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	2	0	0	2
Chain A, Cruzipain	4	0	0	4
acetylcholinesterase	3	0	0	3
calpain II, partial	0	1	0	1
SUMO-1	0	1	0	1
15-lipoxygenase, partial	3	0	0	3
Mcl-1	0	1	0	1
SMAD family member 2	4	0	0	4
SMAD family member 3	4	0	0	4
Valosin-containing protein	0	2	0	2
TSHR protein	1	0	0	1
Estrogen receptor 1	0	1	0	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	5	0	0	5
PINK1	1	0	0	1
envelope glycoprotein	0	1	0	1
nonstructural protein 1	2	0	0	2
Parkin	3	0	0	3
bromodomain adjacent to zinc finger domain 2B	4	0	0	4
heat shock protein 90	0	0	2	2
heat shock 70kDa protein 1A	0	1	0	1
thyrotropin-releasing hormone receptor	1	0	0	1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	4	0	0	4
Caspase-7	1	0	0	1
galactokinase	1	0	0	1
NPC intracellular cholesterol transporter 1 precursor	2	0	0	2
tumor necrosis factor	1	0	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	1	0	0	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	2	0	0	2
neuropeptide Y receptor type 1	0	0	1	1
neuropeptide Y receptor type 2	0	0	1	1
small ubiquitin-related modifier 2 isoform b precursor	0	1	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	2	0	0	2
caspase-3	1	0	0	1
estrogen receptor beta isoform 1	0	1	0	1
huntingtin isoform 2	2	0	0	2
DNA polymerase beta	2	0	0	2
enteropeptidase precursor	1	0	0	1
nuclear factor NF-kappa-B p105 subunit isoform 1	1	0	0	1
fatty acid synthase	0	1	0	1
eukaryotic translation initiation factor 4 gamma 1 isoform 4	0	2	0	2
heat shock protein HSP 90-alpha isoform 2	0	0	0	1
DNA polymerase eta isoform 1	2	0	0	2
heat shock cognate 71 kDa protein isoform 1	0	1	0	1
DNA polymerase iota isoform a (long)	7	0	0	7
eukaryotic translation initiation factor 4E isoform 1	0	2	0	2
urokinase-type plasminogen activator precursor	4	0	0	4
plasminogen precursor	4	0	0	4
urokinase plasminogen activator surface receptor precursor	4	0	0	4
nuclear receptor ROR-gamma isoform 1	6	0	0	6
Vpr	3	0	0	3
histone acetyltransferase KAT2A isoform 1	6	0	0	6
4-(cytidine 5'-phospho)-2-C-methyl-D-erithritol kinase	1	0	0	1
replicative DNA helicase	0	0	0	1
recombinase A	0	0	1	1
exodeoxyribonuclease V subunit RecD	0	1	0	1
exodeoxyribonuclease V subunit RecB	0	1	0	1
exodeoxyribonuclease V subunit RecC	0	1	0	1
POsterior Segregation	0	0	1	1
heat shock cognate 71 kDa protein isoform 2	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	2	0	0	2
5-hydroxytryptamine receptor 4	0	2	0	2
Urokinase-type plasminogen activator	0	1	0	1
Tissue-type plasminogen activator	0	1	0	1
Receptor tyrosine-protein kinase erbB-2	0	2	1	3
Plasminogen activator inhibitor 1	0	1	0	1
Tyrosine-protein kinase Lck	0	2	1	3
Tyrosine-protein kinase Fyn	0	2	1	3
Urokinase-type plasminogen activator	0	1	0	1
Muscarinic acetylcholine receptor M1	0	2	0	2
Muscarinic acetylcholine receptor M3	0	2	0	2
Muscarinic acetylcholine receptor M4	0	2	0	2
Muscarinic acetylcholine receptor M5	0	2	0	2
Alpha-2A adrenergic receptor	0	4	1	5
Replicase polyprotein 1a	0	1	1	2
Replicase polyprotein 1ab	0	2	1	3
Adenosine receptor A3	0	2	0	2
Replicase polyprotein 1ab	0	2	2	4
Muscarinic acetylcholine receptor M2	0	2	0	2
Endoplasmic reticulum chaperone BiP	0	1	0	1
Macrophage migration inhibitory factor	0	3	0	3
Androgen receptor	0	3	0	3
Alpha-1B adrenergic receptor	0	3	0	3
Alpha-2C adrenergic receptor	0	3	0	3
Substance-K receptor	0	2	0	2
Acetylcholinesterase	0	1	0	1
Sodium-dependent noradrenaline transporter	0	2	1	3
Thromboxane-A synthase	0	2	0	2
Adenosine receptor A1	1	1	0	2
Mitogen-activated protein kinase 3	0	1	1	2
5-hydroxytryptamine receptor 2C	0	2	0	2
Mitogen-activated protein kinase 1	0	1	1	2
Adenosine receptor A2a	0	2	0	2
Sodium-dependent serotonin transporter	0	2	0	2
Cytochrome P450 2C19	0	4	0	6
5-hydroxytryptamine receptor 2B	0	2	0	2
Alpha-1A adrenergic receptor	0	3	0	3
Caspase-7	1	0	0	1
Spike glycoprotein	4	0	1	5
Inositol monophosphatase 1	1	0	0	1
Mitogen-activated protein kinase 14	0	1	1	2
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D	0	1	0	1
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D	0	1	0	1
Rap guanine nucleotide exchange factor 4	2	0	0	2
Zinc finger protein mex-5	0	0	1	1
phosphoglycerate kinase	2	0	0	2
heat shock protein 90, putative	0	0	0	1
M1-family alanyl aminopeptidase	0	1	0	1
hypothetical protein CAALFM_CR05890CA	0	0	0	1
H3 histone acetyltransferase	0	0	0	1
BZLF2	0	1	0	1
Genome polyprotein	0	1	0	1
Spike glycoprotein	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Transmembrane protease serine 2	0	0	1	1
Procathepsin L	0	1	1	2
Muscarinic acetylcholine receptor M2	0	2	0	2
Muscarinic acetylcholine receptor M4	0	1	0	1
Muscarinic acetylcholine receptor M5	0	1	0	1
Replicase polyprotein 1ab	0	0	1	1
Muscarinic acetylcholine receptor M1	0	1	0	1
Alpha-2B adrenergic receptor	0	1	0	1
Muscarinic acetylcholine receptor M3	0	1	0	1
Alpha-1D adrenergic receptor	0	2	0	2
Sigma intracellular receptor 2	0	1	0	1
Cyclic GMP-AMP synthase	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	2	0	2
Angiotensin-converting enzyme 2	0	0	1	1
Toll-like receptor 9	0	1	0	1
Toll-like receptor 7	0	1	0	1
Chain A, membrane-associated prostaglandin E synthase-2	0	1	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	2	0	0	2
Chain A, 2-oxoglutarate Oxygenase	5	0	0	5
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	1	0	0	1
peripheral myelin protein 22 isoform 1	2	0	0	2
serine/threonine-protein kinase mTOR isoform 1	1	0	0	1
Prostaglandin-H2 D-isomerase	0	1	0	1
Prostaglandin E synthase	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	2
Prostaglandin G/H synthase 2	0	1	0	2
3',5'-cyclic-AMP phosphodiesterase	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	4	0	4
Cytochrome c oxidase subunit 2	0	1	0	1
Phospholipase A2, major isoenzyme	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	2	1	0	3
Interleukin-8	0	1	0	1
Androgen receptor	0	2	1	3
Neuronal acetylcholine receptor subunit beta-2	2	1	0	3
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	2
Aldo-keto reductase family 1 member B1	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Aldo-keto reductase family 1 member C4	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Sodium-dependent dopamine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Caspase-1	0	1	0	2
Nitric oxide synthase, inducible	0	1	0	1
Adenosine receptor A2a	0	1	0	1
Substance-P receptor	0	1	0	1
Prostaglandin E2 receptor EP3 subtype	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	1
Bifunctional epoxide hydrolase 2	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Prostaglandin E2 receptor EP1 subtype	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	0	1	1
Aldo-keto reductase family 1 member C3	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	1	0	1
C-X-C chemokine receptor type 3	0	1	0	1
Aldo-keto reductase family 1 member C2	0	1	0	1
Prostaglandin D2 receptor	0	2	0	2
Solute carrier organic anion transporter family member 1A3	0	1	0	1
Prostaglandin G/H synthase 2	0	2	0	2
Aldo-keto reductase family 1 member C1	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	2
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Sigma intracellular receptor 2	0	2	0	2
Prostaglandin E2 receptor EP2 subtype	0	1	0	1
Rho-associated protein kinase 2	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Dehydrogenase/reductase SDR family member 9	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Solute carrier organic anion transporter family member 1B3	0	4	0	5
Cytosolic phospholipase A2 gamma	0	1	0	1
Prostaglandin D2 receptor 2	0	1	1	2
Solute carrier organic anion transporter family member 1B1	0	4	0	5
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
potassium voltage-gated channel subfamily H member 2 isoform d	4	0	0	4
N-glycosylase/DNA lyase	0	1	0	1
Polyphenol oxidase 2	0	1	0	1
Myeloperoxidase	0	1	0	1
Formamidopyrimidine-DNA glycosylase	0	1	0	1
DNA gyrase subunit A	0	2	0	2
DNA gyrase subunit B	0	2	0	2
Cytochrome P450 2C8	0	2	0	3
Cytochrome P450 2A6	0	1	0	1
Endonuclease III-like protein 1	0	1	0	1
DNA gyrase subunit B	0	2	0	2
DNA gyrase subunit A	0	2	0	2
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	2	0	3
Pantothenate synthetase	0	1	0	1
Isocitrate lyase	0	1	0	1
Putative FAD-containing monooxygenase MymA	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Endonuclease 8-like 1	0	1	0	1
matrix metalloproteinase 1, partial	0	0	1	1
caspase 7, apoptosis-related cysteine protease	1	0	0	1
P53	1	0	0	1
pyruvate kinase	1	0	0	1
caspase-3	1	0	0	1
histone deacetylase 9 isoform 3	1	0	0	1
Dihydroorotate dehydrogenase (quinone), mitochondrial	0	1	0	1
Aldo-keto reductase family 1 member B1	0	2	0	2
Amine oxidase [flavin-containing] A	0	3	0	3
Endothelin receptor type B	1	0	0	1
Endothelin-1 receptor	1	0	0	1
Sodium-dependent dopamine transporter	0	2	0	2
Dihydroorotate dehydrogenase (quinone), mitochondrial	0	1	0	1
Dihydroorotate dehydrogenase (quinone), mitochondrial	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	1	0	1
Renin	0	1	0	1
Opioid receptor, delta 1b	0	1	0	1
Acetylcholinesterase	0	2	0	2
Opioid receptor homologue	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Translocator protein	0	0	1	1
Histidine decarboxylase	0	0	1	1
Proteinase-activated receptor 1	0	1	1	2
Sodium-dependent serotonin transporter	0	2	0	2
Delta-type opioid receptor	0	1	0	2
Delta-type opioid receptor	0	2	1	4
Kappa-type opioid receptor	0	2	1	4
Mu-type opioid receptor	0	3	1	7
Kappa-type opioid receptor	0	2	1	4
Mu-type opioid receptor	0	2	1	4
UDP-glucuronosyltransferase 1A3	0	0	0	1
Delta-type opioid receptor	0	2	1	4
Kappa-type opioid receptor	0	2	1	4
Mu-type opioid receptor	0	2	1	5
Nociceptin receptor	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	2	0	2
Beta-2 adrenergic receptor	0	1	0	1
Mas-related G-protein coupled receptor member X2	0	0	1	1
Mu-type opioid receptor	0	1	0	1
Chain A, Isoleucyl-tRNA synthetase	0	1	0	1
twin arginine protein translocation system - TatA protein	0	0	0	1
Isoleucine--tRNA ligase	0	1	0	1
L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase	0	1	0	1
Class D beta-lactamase	0	0	0	1
MecA	0	1	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	3	0	0	3
WRN	1	0	0	1
lysosomal alpha-glucosidase preproprotein	2	0	0	2
transcriptional regulator ERG isoform 3	1	0	0	1
microphthalmia-associated transcription factor isoform 9	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	0	0	1
tyrosine-protein kinase Yes	1	0	0	1
Bone morphogenetic protein receptor type-1B	0	0	1	1
Cell division cycle 7-related protein kinase	0	0	1	1
Serine/threonine-protein kinase PLK4	0	0	1	1
ATP-dependent RNA helicase DDX3X	0	0	1	1
Pyridoxal kinase	0	0	1	1
Citron Rho-interacting kinase	0	0	1	1
Serine/threonine-protein kinase Chk1	0	0	1	1
Aurora kinase A	0	0	1	1
Cyclin-G-associated kinase	0	0	1	1
Ephrin type-B receptor 6	0	0	1	1
Peroxisomal acyl-coenzyme A oxidase 3	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 2	0	0	1	1
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	1	1
Testosterone 17-beta-dehydrogenase 3	0	1	0	1
Dynamin-like 120 kDa protein, mitochondrial	0	0	1	1
Putative nucleoside diphosphate kinase	0	0	1	1
Tyrosine-protein kinase JAK2	0	2	0	2
Rho-associated protein kinase 2	0	0	1	1
Serine/threonine-protein kinase ULK1	0	0	1	1
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	1	1
Ribosomal protein S6 kinase alpha-5	0	0	1	1
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	1	1
Ribosomal protein S6 kinase alpha-4	0	0	1	1
Serine/threonine-protein kinase 16	0	0	1	1
Serine/threonine-protein kinase 10	0	0	1	1
Serine/threonine-protein kinase D3	0	0	1	1
Structural maintenance of chromosomes protein 2	0	0	1	1
Mitogen-activated protein kinase kinase kinase 6	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	1	1
Serine/threonine-protein kinase LATS1	0	0	1	1
Serine/threonine-protein kinase PAK 4	0	0	1	1
Tyrosine-protein kinase ABL1	0	0	1	1
High affinity nerve growth factor receptor	0	0	1	1
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	1	1
ADP/ATP translocase 2	0	0	1	1
Protein kinase C beta type	0	0	1	1
Insulin receptor	0	0	1	1
Glycogen phosphorylase, liver form	0	0	1	1
Tyrosine-protein kinase Fes/Fps	0	0	1	1
Macrophage colony-stimulating factor 1 receptor	0	1	0	1
Adenine phosphoribosyltransferase	0	0	1	1
Tyrosine-protein kinase Yes	0	1	1	2
Tyrosine-protein kinase Lyn	0	1	1	2
Proto-oncogene tyrosine-protein kinase receptor Ret	0	1	1	2
Insulin-like growth factor 1 receptor	0	0	1	1
Signal recognition particle receptor subunit alpha	0	0	1	1
Cytochrome c1, heme protein, mitochondrial	0	0	1	1
Hepatocyte growth factor receptor	0	0	1	1
Tyrosine-protein kinase HCK	0	1	1	2
Platelet-derived growth factor receptor beta	0	1	1	2
Tyrosine-protein kinase Fgr	0	1	0	1
Serine/threonine-protein kinase A-Raf	0	0	1	1
Glycogen phosphorylase, brain form	0	0	1	1
Breakpoint cluster region protein	0	0	1	1
Fibroblast growth factor receptor 1	0	0	1	1
DNA topoisomerase 2-alpha	0	0	1	1
Cyclin-dependent kinase 4	0	0	1	1
ADP/ATP translocase 3	0	0	1	1
Inosine-5'-monophosphate dehydrogenase 2	0	0	1	1
Proto-oncogene tyrosine-protein kinase Src	0	1	1	2
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	1	1
Serine/threonine-protein kinase B-raf	0	0	1	1
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	1	1
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	0	1	1
Tyrosine-protein kinase Fer	0	0	1	1
Protein kinase C alpha type	0	0	1	1
cAMP-dependent protein kinase catalytic subunit alpha	0	0	1	1
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	1	1
Casein kinase II subunit alpha'	0	0	1	1
Ras-related protein Rab-6A	0	0	1	1
Cytochrome P450 2B6	0	1	1	3
Ephrin type-A receptor 1	0	0	1	1
Receptor tyrosine-protein kinase erbB-3	0	1	0	1
Multifunctional protein ADE2	0	0	1	1
Nucleoside diphosphate kinase B	0	0	1	1
cAMP-dependent protein kinase catalytic subunit gamma	0	0	1	1
cAMP-dependent protein kinase catalytic subunit beta	0	0	1	1
Ferrochelatase, mitochondrial	0	0	1	1
Ribosomal protein S6 kinase beta-1	0	0	1	1
Tyrosine-protein kinase JAK1	0	2	1	3
G1/S-specific cyclin-E1	0	1	0	1
Cyclin-dependent kinase 2	0	1	1	2
Beta-adrenergic receptor kinase 1	0	0	1	1
Probable ATP-dependent RNA helicase DDX6	0	0	1	1
MAP/microtubule affinity-regulating kinase 3	0	0	1	1
Deoxycytidine kinase	0	0	1	1
Ephrin type-A receptor 2	0	1	1	2
Ephrin type-B receptor 2	0	0	1	1
Non-receptor tyrosine-protein kinase TYK2	0	0	1	1
Phosphatidylethanolamine-binding protein 1	0	0	1	1
Wee1-like protein kinase	0	0	1	1
Heme oxygenase 2	0	0	1	1
S-adenosylmethionine synthase isoform type-2	0	0	1	1
DnaJ homolog subfamily A member 1	0	0	1	1
RAC-alpha serine/threonine-protein kinase	0	0	1	1
RAC-beta serine/threonine-protein kinase	0	0	1	1
Dual specificity protein kinase TTK	0	0	1	1
DNA replication licensing factor MCM4	0	0	1	1
Myosin-10	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 2	0	1	1	2
Receptor-type tyrosine-protein kinase FLT3	0	2	1	3
Bone morphogenetic protein receptor type-1A	0	0	1	1
Activin receptor type-1B	0	0	1	1
TGF-beta receptor type-1	0	0	1	1
TGF-beta receptor type-2	0	0	1	1
Tyrosine-protein kinase CSK	0	1	1	2
Glycine--tRNA ligase	0	0	1	1
Protein kinase C iota type	0	0	1	1
Exosome RNA helicase MTR4	0	0	1	1
Tyrosine-protein kinase Tec	0	1	1	2
Tyrosine-protein kinase TXK	0	1	1	2
Tyrosine-protein kinase ABL2	0	0	1	1
Tyrosine-protein kinase FRK	0	1	1	2
G protein-coupled receptor kinase 6	0	0	1	1
Tyrosine-protein kinase SYK	0	1	1	2
26S proteasome regulatory subunit 6B	0	0	1	1
Mitogen-activated protein kinase 8	0	0	1	1
Mitogen-activated protein kinase 9	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 3	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	1	1
Casein kinase I isoform delta	0	0	1	1
MAP kinase-activated protein kinase 2	0	0	1	1
Elongation factor Tu, mitochondrial	0	0	1	1
Choline-phosphate cytidylyltransferase A	0	0	1	1
Casein kinase I isoform epsilon	0	0	1	1
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	1	1
Dual specificity protein kinase CLK1	0	0	1	1
Dual specificity protein kinase CLK2	0	0	1	1
Glycogen synthase kinase-3 alpha	0	0	1	1
Glycogen synthase kinase-3 beta	0	0	1	1
Cyclin-dependent kinase 7	0	0	1	1
Cyclin-dependent kinase 9	0	0	1	1
Ras-related protein Rab-27A	0	0	1	1
Tyrosine-protein kinase Blk	0	1	1	2
Interleukin-1 receptor-associated kinase 1	0	0	1	1
Ribosomal protein S6 kinase alpha-3	0	0	1	1
Cytoplasmic tyrosine-protein kinase BMX	0	2	1	3
cAMP-dependent protein kinase catalytic subunit PRKX	0	0	1	1
Serine/threonine-protein kinase Nek2	0	0	1	1
Serine/threonine-protein kinase Nek3	0	0	1	1
Tyrosine-protein kinase JAK3	0	1	1	2
Dual specificity mitogen-activated protein kinase kinase 6	0	0	1	1
Serine/threonine-protein kinase PLK1	0	0	1	1
LIM domain kinase 1	0	0	1	1
LIM domain kinase 2	0	0	1	1
Mitogen-activated protein kinase 10	0	0	1	1
Tyrosine--tRNA ligase, cytoplasmic	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	1	1
Ephrin type-B receptor 3	0	0	1	1
Ephrin type-A receptor 5	0	0	1	1
Ephrin type-B receptor 4	0	0	1	1
Ephrin type-A receptor 4	0	0	1	1
Adenylate kinase 2, mitochondrial	0	0	1	1
Adenosine kinase	0	0	1	1
Ras-related protein Rab-10	0	0	1	1
Actin-related protein 3	0	0	1	1
Actin-related protein 2	0	0	1	1
GTP-binding nuclear protein Ran	0	0	1	1
Casein kinase I isoform gamma-2	0	0	1	1
Cyclin-dependent kinase 3	0	0	1	1
Cyclin-dependent kinase 6	0	0	1	1
Cyclin-dependent-like kinase 5	0	0	1	1
Cyclin-dependent kinase 16	0	0	1	1
Cyclin-dependent kinase 17	0	0	1	1
ATP-dependent 6-phosphofructokinase, platelet type	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 1	0	0	1	1
DNA topoisomerase 2-beta	0	0	1	1
Protein kinase C theta type	0	0	1	1
Activin receptor type-1	0	0	1	1
Macrophage-stimulating protein receptor	0	0	1	1
Focal adhesion kinase 1	0	0	1	1
Protein kinase C delta type	0	0	1	1
Tyrosine-protein kinase BTK	0	2	2	4
Activated CDC42 kinase 1	0	0	1	1
Epithelial discoidin domain-containing receptor 1	0	0	1	1
Tyrosine-protein kinase ITK/TSK	0	1	1	2
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	1	1
Tyrosine-protein kinase Mer	0	0	1	1
Serine/threonine-protein kinase 4	0	0	1	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 5	0	0	1	1
Mitogen-activated protein kinase 7	0	0	1	1
Serine/threonine-protein kinase PAK 2	0	0	1	1
Serine/threonine-protein kinase 3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 1	0	0	1	1
Integrin-linked protein kinase	0	0	1	1
Rho-associated protein kinase 1	0	0	1	1
Non-receptor tyrosine-protein kinase TNK1	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	1	1
Activin receptor type-2B	0	0	1	1
Bone morphogenetic protein receptor type-2	0	0	1	1
Protein-tyrosine kinase 6	0	1	1	2
cGMP-dependent protein kinase 1	0	0	1	1
Cyclin-dependent kinase 13	0	0	1	1
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	1	1
Protein-tyrosine kinase 2-beta	0	0	1	1
Maternal embryonic leucine zipper kinase	0	0	1	1
Structural maintenance of chromosomes protein 1A	0	0	1	1
Chromodomain-helicase-DNA-binding protein 4	0	0	1	1
Serine/threonine-protein kinase 38	0	0	1	1
Receptor tyrosine-protein kinase erbB-4	0	1	1	2
Ephrin type-A receptor 7	0	0	1	1
Delta(24)-sterol reductase	0	0	1	1
Ribosomal protein S6 kinase alpha-1	0	1	1	2
Myosin light chain kinase, smooth muscle	0	0	1	1
Mitogen-activated protein kinase 11	0	0	1	1
Serine/threonine-protein kinase STK11	0	0	1	1
Serine/threonine-protein kinase N1	0	0	1	1
Serine/threonine-protein kinase N2	0	0	1	1
Calcium/calmodulin-dependent protein kinase type IV	0	0	1	1
Mitogen-activated protein kinase kinase kinase 11	0	0	1	1
MAP kinase-activated protein kinase 3	0	0	1	1
Discoidin domain-containing receptor 2	0	0	1	1
AP2-associated protein kinase 1	0	0	1	1
Myosin light chain kinase 3	0	0	1	1
Putative heat shock protein HSP 90-beta 2	0	0	1	1
Rab-like protein 3	0	0	1	1
Serine/threonine-protein kinase MRCK alpha	0	0	1	1
Serine/threonine-protein kinase MRCK gamma	0	0	1	1
Acyl-CoA dehydrogenase family member 10	0	0	1	1
Serine/threonine-protein kinase ULK3	0	0	1	1
Uncharacterized protein FLJ45252	0	0	1	1
Acyl-CoA dehydrogenase family member 11	0	0	1	1
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	1	1
Serine/threonine-protein kinase MARK2	0	0	1	1
ATP-dependent RNA helicase DHX30	0	0	1	1
Serine/threonine-protein kinase TAO1	0	0	1	1
STE20-related kinase adapter protein alpha	0	0	1	1
Myosin-14	0	0	1	1
AarF domain-containing protein kinase 1	0	0	1	1
ATP-dependent RNA helicase DDX42	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	1	1
MAP kinase-activated protein kinase 5	0	0	1	1
Misshapen-like kinase 1	0	0	1	1
Atypical kinase COQ8A, mitochondrial	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	1	1
Mitogen-activated protein kinase 15	0	0	1	1
Serine/threonine-protein kinase Nek9	0	0	1	1
Serine/threonine-protein kinase Nek7	0	0	1	1
ATP-dependent RNA helicase DDX1	0	0	1	1
Nuclear receptor subfamily 4 group A member 3	0	1	0	1
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	1	1
Aurora kinase B	0	0	1	1
MAP/microtubule affinity-regulating kinase 4	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1G	0	0	1	1
Serine/threonine-protein kinase Nek1	0	0	1	1
PAS domain-containing serine/threonine-protein kinase	0	0	1	1
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	1	1
EKC/KEOPS complex subunit TP53RK	0	0	1	1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 5	0	0	1	1
Mitogen-activated protein kinase kinase kinase 3	0	0	1	1
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	1	1
Peroxiredoxin-like 2A	0	1	0	1
Nucleolar GTP-binding protein 1	0	0	1	1
Serine/threonine-protein kinase D2	0	0	1	1
NUAK family SNF1-like kinase 2	0	0	1	1
RNA cytidine acetyltransferase	0	0	1	1
Serine/threonine-protein kinase SIK2	0	0	1	1
STE20-like serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase TAO3	0	0	1	1
dCTP pyrophosphatase 1	0	0	1	1
Dual specificity protein kinase CLK4	0	0	1	1
Platelet glycoprotein VI	0	1	0	1
Casein kinase I isoform gamma-1	0	0	1	1
Serine/threonine-protein kinase PAK 6	0	0	1	1
Phenylalanine--tRNA ligase beta subunit	0	0	1	1
BMP-2-inducible protein kinase	0	0	1	1
Obg-like ATPase 1	0	0	1	1
Midasin	0	0	1	1
Interleukin-1 receptor-associated kinase 4	0	0	1	1
Mitogen-activated protein kinase kinase kinase 20	0	0	1	1
Cyclin-dependent kinase 12	0	0	1	1
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	1	1
Serine/threonine-protein kinase 26	0	0	1	1
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	1	1
Serine/threonine-protein kinase NLK	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	1	1
Serine/threonine-protein kinase TBK1	0	0	1	1
Septin-9	0	0	1	1
Ribosomal protein S6 kinase alpha-6	0	0	1	1
TRAF2 and NCK-interacting protein kinase	0	0	1	1
Serine/threonine-protein kinase TAO2	0	0	1	1
Serine/threonine-protein kinase ICK	0	0	1	1
RAC-gamma serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase SIK3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 2	0	0	1	1
Thyroid hormone receptor-associated protein 3	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 3	0	0	1	1
Serine/threonine-protein kinase MRCK beta	0	0	1	1
Interleukin-1 receptor-associated kinase 3	0	0	1	1
Serine/threonine-protein kinase 24	0	0	1	1
Casein kinase I isoform gamma-3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 4	0	0	1	1
GALC protein	2	0	0	2
mu-type opioid receptor isoform MOR-1	0	0	1	1
5-hydroxytryptamine receptor 2A	0	0	1	1
luciferase	0	0	0	1
Fatty acid-binding protein, liver	0	1	0	1
Estrogen receptor	0	2	0	2
Glucocorticoid receptor	0	4	2	11
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Glycine receptor subunit alpha-1	0	4	0	4
Corticosteroid-binding globulin	0	1	0	1
Mineralocorticoid receptor	0	2	1	3
Glutamine synthetase	0	0	1	1
Glycine receptor subunit beta	0	4	0	4
Glycine receptor subunit alpha-2	0	4	0	4
Glycine receptor subunit alpha-3	0	4	0	4
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
dual specificity protein phosphatase 3	0	1	0	1
tyrosine-protein phosphatase non-receptor type 22 isoform 1	0	1	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Beta-hexosaminidase subunit alpha	0	1	0	2
Beta-hexosaminidase subunit beta	0	1	0	1
Dihydrofolate reductase	0	2	1	4
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Dihydrofolate reductase	0	2	0	2
Substance-K receptor	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Pteridine reductase 1	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Trace amine-associated receptor 5	0	0	1	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Multidrug and toxin extrusion protein 1	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR	0	0	1	1
mitogen-activated protein kinase 1	1	0	0	1
Retinol-binding protein 4	0	0	1	1
Beta-lactoglobulin	0	0	1	1
Amyloid-beta precursor protein	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	1	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
NH(3)-dependent NAD(+) synthetase	0	1	0	1
Arylacetamide deacetylase	0	1	0	2
Solute carrier organic anion transporter family member 1A1	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	1	0	1
Glutathione S-transferase omega-1	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Pyruvate kinase PKM	0	0	1	1
Neutral amino acid transporter A	0	1	0	1
Cholinesterase	0	1	0	1
Neutral amino acid transporter B(0)	0	1	0	1
Amino acid transporter	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Alpha-2B adrenergic receptor	0	1	0	1
Alpha-2C adrenergic receptor	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Alpha-1D adrenergic receptor	0	1	0	1
D-alanyl-D-alanine dipeptidase	0	1	0	1
Transporter	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(5)

Research Excerpts

Overview

Treatment

Research

Studies (77)

Protein Targets (1,120)

Ritter Disease

Synonyms(5)

Research Excerpts

Overview

Treatment

Research

Studies (77)

Drugs Studied (70)

Protein Targets (1,120)