Retinal Dystrophies

A group of disorders involving predominantly the posterior portion of the ocular fundus, due to degeneration in the sensory layer of the RETINA; RETINAL PIGMENT EPITHELIUM; BRUCH MEMBRANE; CHOROID; or a combination of these tissues.

Synonym
Retinal Dystrophies

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	2 (3.33)	23.3326
1990's	0 (0.00)	12.5806
2000's	0 (0.00)	18.1394
2010's	37 (61.67)	28.8240
2020's	21 (35.00)	9.53

Drug	Relationship Strength	Studies
glycine	low	1
taurine	low	1
acetazolamide	low	4
2-propanol	low	2
vigabatrin	low	1
tyrosine	low	1
arginine	low	1
methylprednisolone	low	1
thiophenes	low	4
thiazoles	low	2
deuterium	low	1
triamcinolone	low	1
glutamic acid	low	2
sodium azide	low	1
etoposide	low	1
substance p	low	1
brinzolamide	low	2
fingolimod hydrochloride	low	1
levofloxacin	low	1
darunavir	low	1
glycogen	low	1
meropenem	low	1
retinol	low	4
melphalan	low	1
retinaldehyde	low	1
beta carotene	low	1
11-cis-retinal	low	8
dorzolamide	low	4
topiramate	low	1
casein kinase ii	low	1
oxadiazoles	low	1
ptc 124	low	1
indocyanine green	low	2
phosphatidylcholines	low	1
ubiquinone	low	3
emixustat	low	1
cyclic gmp	low	1
eye	low	9

Protein Targets (615)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, Retinaldehyde-binding protein 1	0	0	1	1
Chain A, Retinaldehyde-binding protein 1	0	0	1	1
hypoxia-inducible factor 1 alpha subunit	4	0	0	4
RAR-related orphan receptor gamma	9	0	0	9
GLI family zinc finger 3	10	0	0	10
AR protein	13	0	0	13
aldehyde dehydrogenase 1 family, member A1	6	0	0	6
retinoic acid nuclear receptor alpha variant 1	10	0	0	10
retinoid X nuclear receptor alpha	10	0	0	10
estrogen nuclear receptor alpha	15	0	0	15
peroxisome proliferator-activated receptor delta	8	0	0	8
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	8	0	0	8
activating transcription factor 6	4	0	0	4
v-jun sarcoma virus 17 oncogene homolog (avian)	4	0	0	4
Histone H2A.x	5	0	0	5
thyroid hormone receptor beta isoform a	2	0	0	2
heat shock protein beta-1	5	0	0	5
nuclear factor erythroid 2-related factor 2 isoform 1	11	0	0	11
lamin isoform A-delta10	5	0	0	5
Voltage-dependent calcium channel gamma-2 subunit	6	0	0	6
Glutamate receptor 2	6	2	1	9
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	4	0	0	4
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Beta-lactamase	1	0	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Class Iii Chitinase Chia1	0	1	0	1
Chain A, Carbonic anhydrase 13	0	1	0	1
Chain A, Carbonic anhydrase II	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase	0	1	0	1
Chain B, Carbonic anhydrase	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase	0	0	0	4
Carbonic anhydrase	0	5	0	5
thioredoxin reductase	9	0	0	9
GALC protein	2	0	0	2
nuclear receptor subfamily 1, group I, member 3	9	0	0	9
cytochrome P450 family 3 subfamily A polypeptide 4	5	0	0	5
glucocorticoid receptor [Homo sapiens]	8	0	0	8
estrogen-related nuclear receptor alpha	12	0	0	12
Carbonic anhydrase	0	4	0	4
Carbonic anhydrase	0	4	0	4
arylsulfatase A	5	0	0	5
Carbonic anhydrase	0	4	0	4
euchromatic histone-lysine N-methyltransferase 2	9	0	0	9
Bloom syndrome protein isoform 1	5	0	0	5
geminin	10	0	0	10
peripheral myelin protein 22	4	0	0	4
survival motor neuron protein isoform d	2	0	0	2
muscleblind-like protein 1 isoform 1	3	0	0	3
Gamma-aminobutyric acid receptor subunit pi	5	1	0	6
ATP-binding cassette sub-family C member 3	0	9	0	9
Multidrug resistance-associated protein 4	0	9	0	10
Carbonic anhydrase	0	4	0	4
Solute carrier family 22 member 6	0	1	0	1
Carbonic anhydrase 12	0	5	1	12
Prolyl endopeptidase	0	2	0	2
Carbonic anhydrase-related protein 11	0	1	0	3
Bile salt export pump	0	10	0	10
Glycogen phosphorylase, muscle form	0	1	0	1
Renin	0	2	0	2
Carbonic anhydrase 1	0	8	1	18
Carbonic anhydrase 2	0	9	4	21
Carbonic anhydrase 2	0	2	0	2
Cytochrome P450 1A2	0	1	0	1
Carbonic anhydrase 3	0	5	1	10
Cathepsin B	0	1	0	1
Cytochrome P450 3A4	0	3	0	4
Steryl-sulfatase	0	1	0	1
5-hydroxytryptamine receptor 2C	0	3	0	3
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	2
Cytochrome P450 2C8	0	2	0	2
Cytochrome P450 2D6	0	1	0	1
Cytochrome P450 2A6	0	1	0	1
Cytochrome P450 2C9	0	3	0	3
5-hydroxytryptamine receptor 2A	0	3	0	3
Androgen receptor	0	4	0	4
Gamma-aminobutyric acid receptor subunit beta-1	5	1	0	6
Translocator protein	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	5	1	0	6
Gamma-aminobutyric acid receptor subunit gamma-2	5	1	0	6
Gamma-aminobutyric acid receptor subunit alpha-5	5	1	0	6
Gamma-aminobutyric acid receptor subunit alpha-3	5	1	0	6
Cannabinoid receptor 1	0	1	0	1
Arachidonate 5-lipoxygenase-activating protein	0	2	0	2
Cytochrome P450 2B6	0	1	0	1
Carbonic anhydrase 4	0	8	1	14
Carbonic anhydrase 6	0	5	1	11
Gamma-aminobutyric acid receptor subunit gamma-1	5	1	0	6
Gamma-aminobutyric acid receptor subunit alpha-2	5	1	0	6
Carbonic anhydrase 5A, mitochondrial	0	4	0	4
Adenosine receptor A1	0	1	0	2
Serum paraoxonase/arylesterase 1	0	2	0	2
Dipeptidyl peptidase 4	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	5	1	0	6
Gamma-aminobutyric acid receptor subunit gamma-3	5	1	0	6
Endochitinase	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	5	1	0	6
Adenosine receptor A2a	0	1	0	2
5-hydroxytryptamine receptor 2B	0	3	0	3
Sodium-dependent serotonin transporter	0	1	0	1
Delta-type opioid receptor	0	4	0	4
Cytochrome P450 2C19	0	2	0	2
Delta-type opioid receptor	0	4	0	4
Mu-type opioid receptor	0	5	0	5
Carbonic anhydrase 5A, mitochondrial	0	6	2	14
Carbonic anhydrase	0	4	0	5
Kappa-type opioid receptor	0	1	0	1
Carbonic anhydrase 7	0	5	1	11
Carbonic anhydrase	0	1	0	1
D(1A) dopamine receptor	1	1	0	2
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Carbonic anhydrase	0	4	0	5
D(2) dopamine receptor	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-1	5	1	0	6
Gamma-aminobutyric acid receptor subunit beta-3	5	1	0	6
Gamma-aminobutyric acid receptor subunit beta-2	5	1	0	6
Cholinesterase	0	1	0	1
Carbonic anhydrase	0	4	0	4
Mu-type opioid receptor	0	4	0	4
Fatty-acid amide hydrolase 1	0	3	0	3
Beta-carbonic anhydrase 1	0	4	0	4
Carbonic anhydrase 2	0	4	0	4
Glutamate receptor ionotropic, NMDA 2B	0	6	2	10
Squalene synthase	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	2	0	2
Carbonic anhydrase 9	0	7	1	14
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase, alpha family	0	4	0	4
Carbonic anhydrase	0	4	0	5
Carbonic anhydrase 3	0	1	0	1
Carbonic anhydrase	0	3	0	5
Carbonic anhydrase	0	4	0	6
Carbonic anhydrase	0	4	0	4
Sigma intracellular receptor 2	0	1	0	1
Delta carbonic anhydrase	0	4	0	4
Sigma non-opioid intracellular receptor 1	0	1	0	1
Renin	0	1	0	1
Carbonic anhydrase	0	4	0	5
Endochitinase A1	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	1
Carbonic anhydrase 13	0	5	1	7
GABA theta subunit	5	1	0	6
Canalicular multispecific organic anion transporter 1	0	10	0	11
Carbonic anhydrase 4	0	7	0	7
Carbonic anhydrase 15	0	4	0	6
Acidic mammalian chitinase	0	1	0	1
Carbonic anhydrase 13	0	5	0	8
Carbonic anhydrase 7	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	5	1	0	6
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase 14	0	5	1	12
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 2, isoform A	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	5	1	12
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	3	0	0	3
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
phosphopantetheinyl transferase	4	0	0	4
NFKB1 protein, partial	3	0	0	3
GLS protein	3	0	0	3
thyroid stimulating hormone receptor	3	0	0	3
alpha-galactosidase	1	0	0	1
cytochrome P450 2C19 precursor	2	0	0	2
chromobox protein homolog 1	5	0	0	5
flap endonuclease 1	1	0	0	1
DNA polymerase iota isoform a (long)	4	0	0	4
muscarinic acetylcholine receptor M1	1	0	0	1
lethal factor (plasmid)	3	0	0	3
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, inducible	0	0	0	1
Nitric oxide synthase, inducible	0	0	1	3
Cationic amino acid transporter 3	0	1	0	1
ATP-dependent phosphofructokinase	3	0	0	3
TDP1 protein	8	0	0	8
core protein, partial	0	1	0	1
histone acetyltransferase KAT2A isoform 1	2	0	0	2
Solute carrier organic anion transporter family member 1B3	0	4	0	4
Solute carrier organic anion transporter family member 1B1	0	2	0	2
Chain A, CARBONIC ANHYDRASE IV	0	1	0	1
cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 7	0	0	0	1
cytochrome P450 2D6	4	0	0	4
bromodomain adjacent to zinc finger domain 2B	2	0	0	2
importin subunit beta-1 isoform 1	2	0	0	2
snurportin-1	2	0	0	2
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
Chain A, Protein kinase CK2, alpha Subunit	0	1	0	1
Chain A, PROTEIN KINASE CK2, alpha SUBUNIT	0	1	0	1
Chain A, Protein Kinase Ck2, Alpha Subunit	0	1	0	1
Chain A, Ferritin light chain	1	0	0	1
endonuclease IV	2	0	0	2
dopamine D1 receptor	1	0	0	1
ATAD5 protein, partial	2	0	0	2
Thrombopoietin	1	0	0	1
Parkin	1	0	0	1
NPC intracellular cholesterol transporter 1 precursor	1	0	0	1
peripheral myelin protein 22 isoform 1	2	0	0	2
mitogen-activated protein kinase 1	2	0	0	2
ras-related protein Rab-9A	1	0	0	1
serine/threonine-protein kinase mTOR isoform 1	1	0	0	1
cytochrome P450 3A4 isoform 1	5	0	0	5
Serine/threonine-protein kinase Sgk1	0	1	0	1
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	1	1	2
Casein kinase II subunit alpha	0	1	0	1
Casein kinase II subunit alpha'	0	2	0	2
Cyclin-A2	0	1	0	1
Cyclin-dependent kinase 2	0	1	0	1
Casein kinase II subunit beta	0	2	0	2
Casein kinase II subunit beta	0	1	0	1
Casein kinase II subunit alpha	0	2	0	2
Cyclin-A1	0	1	0	1
Dual specificity mitogen-activated protein kinase kinase 1	0	1	0	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	1	0	1
Ribosomal protein S6 kinase alpha-1	0	1	0	1
Casein kinase II subunit alpha 3	0	2	0	2
Single-stranded DNA cytosine deaminase	1	0	0	1
Phosphodiesterase	0	1	0	1
Multidrug resistance-associated protein 5	0	0	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	1	0	1
Chain A, Pol Polyprotein	0	1	0	1
Chain A, Pol Polyprotein	0	1	0	1
Chain B, Pol Polyprotein	0	1	0	1
Chain A, Pol Polyprotein	0	1	0	1
Chain B, Pol Polyprotein	0	1	0	1
Chain A, HIV-1 Protease	0	1	0	1
Chain B, HIV-1 Protease	0	1	0	1
Chain A, protease	0	1	0	1
Chain B, protease	0	1	0	1
Chain A, Protease	0	1	0	1
Chain B, Protease	0	1	0	1
Chain A, Protease	0	1	0	1
Chain B, Protease	0	1	0	1
Chain A, Protease	0	1	0	1
Chain B, Protease	0	1	0	1
Chain A, Protease (Retropepsin)	0	0	1	1
Chain B, Protease (Retropepsin)	0	0	1	1
Chain A, Protease (Retropepsin)	0	0	1	1
Chain B, Protease (Retropepsin)	0	0	1	1
Chain A, HIV-1 Protease	0	1	0	1
Chain B, HIV-1 Protease	0	1	0	1
Chain A, HIV-1 Protease	0	1	0	1
Chain B, HIV-1 Protease	0	1	0	1
Chain A, HIV-1 Protease	0	1	0	1
Chain B, HIV-1 Protease	0	1	0	1
Chain A, HIV-1 Protease	0	1	0	1
Chain B, HIV-1 Protease	0	1	0	1
Chain A, HIV-1 Protease	0	1	0	1
Chain B, HIV-1 Protease	0	1	0	1
Chain A, HIV-1 Protease	0	1	0	1
Chain B, HIV-1 Protease	0	1	0	1
Chain A, Protease	0	0	1	1
Chain B, Protease	0	0	1	1
Chain A, Protease	0	0	1	1
Chain B, Protease	0	0	1	1
Chain A, Protease	0	0	1	1
Chain B, Protease	0	0	1	1
Chain A, Protease	0	0	1	1
Chain B, Protease	0	0	1	1
Chain A, Protease	0	0	1	1
Chain B, Protease	0	0	1	1
Chain A, Protease	0	0	1	1
Chain B, Protease	0	0	1	1
Chain A, Protease	0	0	1	1
Chain B, Protease	0	0	1	1
Chain A, Protease	0	0	1	1
Chain B, Protease	0	0	1	1
Chain A, Protease	0	0	1	1
Chain B, Protease	0	0	1	1
Chain A, Protease	0	0	1	1
Chain B, Protease	0	0	1	1
Chain A, Protease	0	0	1	1
Chain B, Protease	0	0	1	1
Chain A, Protease	0	0	1	1
Chain B, Protease	0	0	1	1
Chain A, Protease	0	1	0	1
Chain B, Protease	0	1	0	1
Chain A, HIV-1 protease	0	0	1	1
Chain B, HIV-1 protease	0	0	1	1
Chain A, HIV-1 protease	0	0	1	1
Chain B, HIV-1 protease	0	0	1	1
Chain A, HIV-1 Protease	0	0	1	1
Chain B, HIV-1 Protease	0	0	1	1
Chain A, Protease	0	0	1	1
Chain B, Protease	0	0	1	1
Chain A, Protease	0	1	0	1
Chain B, Protease	0	1	0	1
Chain A, Protease	0	1	0	1
Chain B, Protease	0	1	0	1
Chain A, Protease	0	1	0	1
Chain B, Protease	0	1	0	1
Chain A, Protease	0	1	0	1
Chain B, Protease	0	1	0	1
Chain A, Protease	0	1	0	1
Chain B, Protease	0	1	0	1
Chain A, HIV-1 protease	0	1	0	1
Chain B, HIV-1 protease	0	1	0	1
Chain A, HIV-1 protease	0	1	0	1
Chain B, HIV-1 protease	0	1	0	1
Chain A, HIV-1 protease	0	1	0	1
Chain B, HIV-1 protease	0	1	0	1
Chain A, Protease	0	0	1	1
Chain B, Protease	0	0	1	1
Chain A, Pol polyprotein	0	1	0	1
Chain B, Pol polyprotein	0	1	0	1
EWS/FLI fusion protein	5	0	0	5
pregnane X nuclear receptor	11	0	0	11
G	5	0	0	5
nuclear receptor subfamily 1, group I, member 2	3	0	0	3
potassium voltage-gated channel subfamily H member 2 isoform d	4	0	0	4
Interferon beta	6	0	0	6
HLA class I histocompatibility antigen, B alpha chain	5	0	0	5
Gag-Pol polyprotein	0	1	0	1
ATP-dependent translocase ABCB1	0	3	0	5
Replicase polyprotein 1ab	0	1	0	1
Replicase polyprotein 1ab	0	1	0	1
Gag-Pol polyprotein	0	0	1	1
Potassium voltage-gated channel subfamily E member 1	0	1	0	1
Alpha-1B adrenergic receptor	0	1	0	1
Alpha-1D adrenergic receptor	0	1	0	1
Alpha-1A adrenergic receptor	0	1	0	1
Potassium voltage-gated channel subfamily KQT member 1	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Sodium channel protein type 5 subunit alpha	0	1	0	1
Protease	0	2	0	4
Inositol hexakisphosphate kinase 1	5	0	0	5
Gag-Pol polyprotein	0	1	0	1
Potassium voltage-gated channel subfamily D member 3	0	1	0	1
Protease	0	2	2	5
cytochrome P450 2C9, partial	5	0	0	5
Chain A, CARBONIC ANHYDRASE II	0	1	0	1
Chain A, CARBONIC ANHYDRASE II	0	1	0	1
Chain A, CARBONIC ANHYDRASE II	0	1	0	1
Androgen receptor	0	1	0	1
glp-1 receptor, partial	4	0	0	4
SMAD family member 2	5	0	0	5
SMAD family member 3	5	0	0	5
caspase 7, apoptosis-related cysteine protease	3	0	0	3
progesterone receptor	5	0	0	5
67.9K protein	1	0	0	1
peroxisome proliferator activated receptor gamma	5	0	0	5
vitamin D (1,25- dihydroxyvitamin D3) receptor	5	0	0	5
caspase-3	3	0	0	3
LMP1 [Human herpesvirus 4]	0	0	0	1
thyroid stimulating hormone receptor	4	0	0	4
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	3	0	0	3
nuclear factor erythroid 2-related factor 2 isoform 2	4	0	0	4
thyroid hormone receptor beta isoform 2	5	0	0	5
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	1	0	1
urokinase-type plasminogen activator precursor	2	0	0	2
plasminogen precursor	2	0	0	2
urokinase plasminogen activator surface receptor precursor	2	0	0	2
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
nuclear receptor coactivator 3 isoform a	0	1	0	1
Prothrombin	0	0	1	2
Regulatory protein E2	0	0	1	1
Cellular tumor antigen p53	6	0	0	6
ATP-dependent translocase ABCB1	0	1	0	1
DNA topoisomerase 1	0	1	0	2
DNA topoisomerase 2-alpha	0	1	1	7
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
DNA topoisomerase 2	0	0	0	1
ATP-dependent translocase ABCB1	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	0	0	1
Glutamate receptor ionotropic, NMDA 1	0	4	2	8
Caspase-3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	4	2	8
Glutamate receptor ionotropic, NMDA 2C	0	4	2	8
DNA topoisomerase 2-alpha	0	0	0	1
DNA topoisomerase 2-beta	0	1	1	8
Glutamate receptor ionotropic, NMDA 2D	0	4	2	8
Tubulin beta-2B chain	0	1	0	1
Integrase	0	2	0	2
Similar to alpha-tubulin isoform 1	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	4	2	8
ATPase family AAA domain-containing protein 5	6	0	0	6
Ataxin-2	6	0	0	6
Glutamate receptor ionotropic, NMDA 3A	0	4	2	8
Sphingosine 1-phosphate receptor 1	0	0	1	1
RCG53912, isoform CRA_a	0	0	0	1
Sphingosine kinase 1	0	0	0	1
Sphingosine kinase 2	0	0	0	1
Sphingosine kinase 1	0	0	0	1
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
regulator of G-protein signaling 4	2	0	0	2
beta-2 adrenergic receptor	1	0	0	1
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	1	0	0	1
Metabotropic glutamate receptor 8	0	2	0	2
Metabotropic glutamate receptor 6	0	1	1	3
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Excitatory amino acid transporter 4	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Glutathione reductase, mitochondrial	0	2	0	2
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
Integrin beta-3	1	0	1	2
Integrin alpha-IIb	1	0	1	2
ATP-citrate synthase	0	1	0	1
Glutamate receptor 1	0	2	1	3
Glutamate receptor 3	0	2	1	3
Glutamate receptor 4	0	2	1	3
Glutamate receptor ionotropic, kainate 1	0	2	1	3
Metabotropic glutamate receptor 1	0	1	1	2
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 5	0	0	1	1
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Glutamate receptor ionotropic, kainate 1	0	1	1	2
Metabotropic glutamate receptor 5	0	1	1	3
Glutamate receptor ionotropic, kainate 2	0	2	1	3
Glutamate receptor 1	0	2	1	3
Glutamate receptor 2	0	2	1	3
Glutamate receptor 3	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	2	0	2
Excitatory amino acid transporter 1	0	2	0	3
Excitatory amino acid transporter 2	0	2	0	3
Excitatory amino acid transporter 3	0	2	0	3
Metabotropic glutamate receptor 8	0	0	1	1
Glutamate receptor 4	0	2	1	3
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Glutamate receptor ionotropic, kainate 4	0	2	0	2
Glutamate carboxypeptidase 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	1	0	1
Glutamate receptor ionotropic, kainate 2	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	1	0	1
Metabotropic glutamate receptor 1	0	1	1	3
Metabotropic glutamate receptor 2	0	1	1	3
Metabotropic glutamate receptor 7	0	1	1	3
Metabotropic glutamate receptor 3	0	1	1	3
Metabotropic glutamate receptor 4	0	1	1	3
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Glutamate receptor ionotropic, kainate 5	0	1	0	1
Carbonic anhydrase-like protein, putative	0	0	0	2
Glutamate receptor ionotropic, kainate 5	0	2	0	2
Glutamate racemase	0	0	0	1
Prolyl 4-hydroxylase	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
Glycine receptor subunit alpha-1	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent glycine transporter 1	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	2	0	2
Proton-coupled amino acid transporter 1	0	2	0	2
Serine racemase	0	1	0	1
Olfactory receptor 51E2	0	0	1	1
Sodium- and chloride-dependent glycine transporter 2	0	1	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	1	0	0	1
Chain A, 2-oxoglutarate Oxygenase	1	0	0	1
Replicase polyprotein 1ab	0	1	0	1
CAAX prenyl protease 2 isoform 2	0	0	0	1
DNA polymerase beta	1	0	0	1
streptokinase A precursor	0	0	2	2
Bile salt export pump	0	1	0	1
Tubulin beta-4A chain	0	1	0	1
Tubulin beta chain	0	1	0	1
Tubulin alpha-3C chain	0	1	0	1
Spike glycoprotein	2	0	0	2
Tubulin alpha-1B chain	0	1	0	1
Tubulin alpha-4A chain	0	1	0	1
Tubulin beta-4B chain	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA primase	0	1	0	1
Tubulin beta-3 chain	0	1	0	1
Tubulin beta-2A chain	0	1	0	1
Tubulin beta-8 chain	0	1	0	1
Tubulin alpha-3E chain	0	1	0	1
Tubulin alpha-1A chain	0	1	0	1
Multidrug and toxin extrusion protein 1	0	1	0	1
Tubulin alpha-1C chain	0	1	0	1
Tubulin beta-6 chain	0	1	0	1
Tubulin beta-2B chain	0	1	0	1
Tubulin beta-1 chain	0	1	0	1
15-lipoxygenase, partial	3	0	0	3
Fumarate hydratase	1	0	0	1
USP1 protein, partial	3	0	0	3
thioredoxin glutathione reductase	2	0	0	2
Smad3	2	0	0	2
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	3	0	0	3
estrogen receptor 2 (ER beta)	5	0	0	5
farnesoid X nuclear receptor	3	0	0	3
polyprotein	1	0	0	1
glucocerebrosidase	2	0	0	2
aryl hydrocarbon receptor	4	0	0	4
Caspase-7	2	0	0	2
caspase-3	2	0	0	2
Nuclear receptor ROR-gamma	4	0	0	4
TAR DNA-binding protein 43	1	0	0	1
Large neutral amino acids transporter small subunit 1	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase type 2	0	0	1	2
Metallo-beta-lactamase VIM-11	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Metallo-beta-lactamase VIM-19	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase TEM	0	0	0	1
B2 metallo-beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-13	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	1	2
Metallo-b-lactamase	0	0	0	1
Beta-lactamase IMP-1	0	0	0	1
BlaVIM-1	0	0	0	1
Beta-lactamase	0	0	0	1
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	1
Histamine H3 receptor	0	0	0	1
Beta-lactamase class B VIM-2	0	0	1	2
Beta-lactamase	0	0	0	1
Beta-lactamase VIM-1	0	0	0	1
acetylcholinesterase	4	0	0	4
PPM1D protein	1	0	0	1
nonstructural protein 1	1	0	0	1
IDH1	2	0	0	2
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Glucocorticoid receptor	0	4	0	4
Glycine receptor subunit alpha-1	0	4	0	4
Glycine receptor subunit beta	0	4	0	4
Glycine receptor subunit alpha-2	0	4	0	4
Glycine receptor subunit alpha-3	0	4	0	4
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Luciferase	3	0	0	3
histone deacetylase 9 isoform 3	1	0	0	1
nuclear receptor ROR-gamma isoform 1	3	0	0	3
Flavin reductase (NADPH)	0	0	1	1
Chain A, Cellular retinoic acid-binding protein 2	0	0	1	1
Chain A, Cellular retinoic acid-binding protein 2	0	0	1	1
interleukin 8	2	0	0	2
pregnane X receptor	3	0	0	3
cellular tumor antigen p53 isoform a	1	0	0	1
Aldo-keto reductase family 1 member B10	0	0	0	2
Amyloid-beta precursor protein	0	2	0	2
Aldo-keto reductase family 1 member B1	0	0	0	1
Alpha-synuclein	0	2	0	2
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR	0	0	1	1
Chain A, Cruzipain	2	0	0	2
Microtubule-associated protein tau	1	0	0	1
vitamin D3 receptor isoform VDRA	1	0	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	1	0	0	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	1	0	0	1
Retinol-binding protein 4	0	0	1	1
Beta-lactoglobulin	0	0	1	1
Disintegrin and metalloproteinase domain-containing protein 17	1	0	0	1
Laccase	0	1	0	1
DNA polymerase kappa isoform 1	2	0	0	2
Substance-P receptor	0	2	0	2
Neuromedin-K receptor	0	0	1	1
Substance-K receptor	0	1	1	2
Substance-K receptor	0	2	0	2
Substance-P receptor	0	2	1	3
Neuromedin-K receptor	0	1	1	2
Substance-P receptor	0	1	0	1
Substance-K receptor	0	1	0	1
Substance-K receptor	0	1	0	1
Growth hormone secretagogue receptor type 1	0	0	1	1
Mas-related G-protein coupled receptor member X2	0	0	1	1
Sodium- and chloride-dependent taurine transporter	0	1	0	1
Chain A, Carbonic anhydrase 1	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Chain A, HADH2 protein	1	0	0	1
Chain B, HADH2 protein	1	0	0	1
procathepsin L isoform 1 preproprotein	0	1	0	1
Cytochrome P450 2J2	0	1	0	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Polyphenol oxidase 2	0	0	0	1
Plasma kallikrein	0	0	0	1
SLC16A10 protein	0	0	0	1
Tubulin--tyrosine ligase	0	1	0	1
Monocarboxylate transporter 10	0	0	0	1
Taste receptor type 2 member 14	0	0	0	1
D(1A) dopamine receptor	1	0	0	1
Gamma-aminobutyric acid type B receptor subunit 2	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Gamma-aminobutyric acid type B receptor subunit 1	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research

Studies (60)

Protein Targets (615)

Retinal Dystrophies

Synonyms(1)

Research

Studies (60)

Drugs Studied (44)

Protein Targets (615)