Pyelonephritis, Xanthogranulomatous

A chronic inflammatory condition of the KIDNEY resulting in diffuse renal destruction, a grossly enlarged and nonfunctioning kidney associated with NEPHROLITHIASIS and KIDNEY STONES.

Synonym
Xanthogranulomatous Pyelonephritis
Pyelonephritis, Xanthogranulomatous

Excerpt	Reference
"Xanthogranulomatous pyelonephritis is a rare disease that may mimic various renal lesions, especially renal tumors, in its focal form."	( Coquillat, P; Dalsoglio, S; Descotes, JL; Michel, A; Mollier, S; Pasquier, D; Rambeaud, JJ, 1995)
"Xanthogranulomatous pyelonephritis is a particular form of chronic pyelonephritis."	( Benouachane, T; Khattab, M; Msefer-Alaoui, F; Outarahout, O, 1998)
"Focal xanthogranulomatous pyelonephritis is an unusual form of chronic renal infection that is difficult to diagnose prior to surgery."	( Andrianne, R; Boverie, J; de Leval, J; Reul, O; Waltregny, D, 2001)
"Xanthogranulomatous pyelonephritis is an uncommon disease in children."	( Chang, JW; Chen, SJ; Chin, TW; Chu, YK; Pan, CC; Tiu, CM; Tsai, H; Yang, LY, 2004)
"Xanthogranulomatous pyelonephritis is frequently associated with urinary tract obstruction or nephrolithiasis."	( Chen, ML; Ho, CI; Wen, YK, 2008)
"Xanthogranulomatous pyelonephritis is a chronic, inflammatory disease of the kidney rarely found in the pediatric population."	( Chalmers, D; Kim, C; Marietti, S, 2010)
"Xanthogranulomatous pyelonephritis is an uncommon disorder of the kidney that is characterised by chronic inflammation and extensive destruction of the involved kidney usually associated with renal calculus and obstruction."	( Datta, B; Datta, C; Pahari, DK, 2014)
"Xanthogranulomatous pyelonephritis is a rare form of chronic pyelonephritis in which the involved areas of the kidneys are destroyed and replaced by foam cells."	( Garrido-Abad, P; Platas-Sancho, A; Rodríguez-Cabello, MÁ; Vera-Berón, R, 2018)
"Xanthogranulomatous pyelonephritis is a rare disease that was often accompanied with urinary obstruction."	( Liu, Y; Tong, G; Wen, Z, 2022)

Excerpt	Reference
"In this first report of xanthogranulomatous pyelonephritis in a patient with leukemia and splenic abscess, we provide a short review of xanthogranulomatous pyelonephritis successfully treated with antibiotics only."	( Chen, ML; Ho, CI; Wen, YK, 2008)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	4 (11.76)	23.3326
1990's	6 (17.65)	12.5806
2000's	12 (35.29)	18.1394
2010's	10 (29.41)	28.8240
2020's	2 (5.88)	9.53

Drug	Relationship Strength	Studies
pk 11195	low	1
cefuroxime	low	2
ciprofloxacin	low	4
pentetic acid	low	1
guaifenesin	low	1
ofloxacin	low	1
sulfamethoxazole	low	1
trimethoprim	low	2
prednisolone	low	1
framycetin	low	1
cephalexin	low	1
cefmetazole	low	1
captopril	low	1
pefloxacin	low	1
cephalosporin c	low	1
fluorodeoxyglucose f18	low	3
voriconazole	low	1
levofloxacin	low	1
technetium tc 99m pentetate	low	1
trimethoprim, sulfamethoxazole drug combination	low	2
clindamycin	low	1
amoxicillin-potassium clavulanate combination	low	2
crizotinib	low	1
ro13-9904	low	2
epidermal growth factor	low	1

Protein Targets (860)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, angiotensin converting enzyme	0	1	0	1
Chain A, angiotensin converting enzyme	0	1	0	1
Chain A, HADH2 protein	4	0	0	4
Chain B, HADH2 protein	4	0	0	4
Chain A, 2-oxoglutarate Oxygenase	5	0	0	5
15-lipoxygenase, partial	2	0	0	2
phosphopantetheinyl transferase	2	0	0	2
Microtubule-associated protein tau	3	0	0	3
Thrombopoietin	1	0	0	1
AR protein	5	0	0	5
thioredoxin glutathione reductase	1	0	0	1
cytochrome P450 family 3 subfamily A polypeptide 4	5	0	0	5
Metallo-beta-lactamase type 2	0	1	1	2
euchromatic histone-lysine N-methyltransferase 2	7	0	0	7
peripheral myelin protein 22 isoform 1	3	0	0	3
chromobox protein homolog 1	2	0	0	2
M-phase phosphoprotein 8	2	0	0	2
transient receptor potential cation channel subfamily V member 1	1	0	0	1
lamin isoform A-delta10	3	0	0	3
ATP-binding cassette sub-family C member 3	0	9	0	9
Multidrug resistance-associated protein 4	0	9	0	9
Bile salt export pump	0	11	0	11
Prothrombin	0	1	0	1
Renin	0	1	0	1
Neprilysin	0	1	0	1
Neprilysin	0	1	0	1
Leukotriene A-4 hydrolase	0	2	1	3
EEF1AKMT4-ECE2 readthrough transcript protein	0	1	0	1
Angiotensin-converting enzyme	0	2	1	3
Angiotensin-converting enzyme	0	2	0	3
Leukotriene A-4 hydrolase	0	1	0	1
Thymidine phosphorylase	0	0	1	1
Prostaglandin G/H synthase 1	0	1	0	1
Prostaglandin G/H synthase 2	0	2	1	3
Endothelin-converting enzyme 1	0	1	0	1
Succinyl-diaminopimelate desuccinylase	0	2	0	2
Angiotensin-converting enzyme	0	2	0	2
Solute carrier family 15 member 1	0	2	0	2
Beta-lactamase TEM	0	1	0	1
Mu-type opioid receptor	0	1	1	2
TAR DNA-binding protein 43	2	0	0	2
Beta-lactamase	0	2	0	3
Canalicular multispecific organic anion transporter 1	0	9	0	9
Beta-lactamase	0	2	0	2
Angiotensin-converting enzyme 2	0	1	0	1
Beta-lactamase class B VIM-2	0	1	1	2
ATP-dependent phosphofructokinase	3	0	0	3
Solute carrier family 22 member 8	0	1	0	1
Insulin-degrading enzyme	0	1	0	1
Solute carrier family 15 member 1	0	3	0	3
Solute carrier family 15 member 2	0	2	0	2
Solute carrier family 15 member 2	0	2	0	3
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	2	0	0	2
Chain A, Putative fructose-1,6-bisphosphate aldolase	2	0	0	2
TDP1 protein	7	0	0	7
aldehyde dehydrogenase 1 family, member A1	6	0	0	6
glucocorticoid receptor [Homo sapiens]	4	0	0	4
bromodomain adjacent to zinc finger domain 2B	1	0	0	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	3	0	0	3
vitamin D3 receptor isoform VDRA	1	0	0	1
mitogen-activated protein kinase 1	2	0	0	2
nuclear factor erythroid 2-related factor 2 isoform 1	3	0	0	3
Solute carrier family 22 member 6	0	2	0	2
Interferon beta	4	0	0	4
B2 metallo-beta-lactamase	0	0	0	1
Solute carrier family 22 member 8	0	1	0	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	2	0	0	2
Chain A, Cruzipain	1	0	0	1
EWS/FLI fusion protein	6	0	0	6
cytochrome P450 2C9 precursor	1	0	0	1
Gamma-aminobutyric acid receptor subunit pi	1	4	1	6
Cytochrome P450 1A2	0	1	0	1
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
Cytochrome P450 3A4	0	4	0	4
DNA gyrase subunit B	0	1	0	2
DNA gyrase subunit A	0	2	0	5
DNA gyrase subunit B	0	2	0	5
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	2
DNA topoisomerase 4 subunit A	0	1	0	2
Cytochrome P450 2D6	0	1	0	1
DNA topoisomerase 2-alpha	0	1	1	5
Cytochrome P450 2C9	0	4	0	4
Gamma-aminobutyric acid receptor subunit beta-1	1	4	1	6
Gamma-aminobutyric acid receptor subunit delta	1	4	1	6
Gamma-aminobutyric acid receptor subunit gamma-2	1	4	1	6
Gamma-aminobutyric acid receptor subunit alpha-5	1	4	1	6
Gamma-aminobutyric acid receptor subunit alpha-3	1	4	1	6
DNA gyrase subunit A	0	1	0	2
Gamma-aminobutyric acid receptor subunit gamma-1	1	4	1	6
Gamma-aminobutyric acid receptor subunit alpha-2	1	4	1	6
Gamma-aminobutyric acid receptor subunit alpha-4	1	4	1	6
Gamma-aminobutyric acid receptor subunit gamma-3	1	4	1	6
Gamma-aminobutyric acid receptor subunit alpha-6	1	4	1	6
Cytochrome P450 2C19	0	2	0	2
Multidrug resistance protein MdtK	0	0	1	1
Histamine H2 receptor	2	0	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	1	4	1	6
Gamma-aminobutyric acid receptor subunit beta-3	1	4	1	6
Gamma-aminobutyric acid receptor subunit beta-2	1	4	1	6
DNA gyrase subunit B	0	2	0	3
DNA gyrase subunit A	0	3	0	4
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	0	0	1
Potassium voltage-gated channel subfamily H member 2	0	7	0	8
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	1
Integrase	0	1	0	1
GABA theta subunit	1	4	1	6
Gamma-aminobutyric acid receptor subunit epsilon	1	4	1	6
Protein-arginine deiminase type-4	0	3	0	3
Leukotriene C4 synthase	0	0	1	1
Fumarate hydratase	2	0	0	2
PPM1D protein	1	0	0	1
G	2	0	0	2
cytochrome P450 2D6	1	0	0	1
polyprotein	2	0	0	2
tyrosine-protein kinase Yes	1	0	0	1
Bone morphogenetic protein receptor type-1B	0	0	1	1
Membrane-associated progesterone receptor component 1	0	0	1	1
Cell division cycle 7-related protein kinase	0	0	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	0	0	1	1
Serine/threonine-protein kinase PLK4	0	0	1	1
Serine/threonine-protein kinase 25	0	0	1	1
ATP-dependent RNA helicase DDX3X	0	0	1	1
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	0	0	1	1
Pyridoxal kinase	0	0	1	1
Citron Rho-interacting kinase	0	0	1	1
Serine/threonine-protein kinase RIO3	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 7	0	0	1	1
Serine/threonine-protein kinase Chk1	0	0	1	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	1	1
Peripheral plasma membrane protein CASK	0	0	1	1
Aurora kinase A	0	0	1	1
Cyclin-G-associated kinase	0	0	1	1
Serine/threonine-protein kinase DCLK1	0	0	1	1
Inhibitor of nuclear factor kappa-B kinase subunit alpha	0	0	1	1
Muscle, skeletal receptor tyrosine-protein kinase	0	0	1	1
Ephrin type-B receptor 6	0	0	1	1
Peroxisomal acyl-coenzyme A oxidase 3	0	0	1	1
Mitogen-activated protein kinase 13	0	0	1	1
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2	0	1	0	1
3-phosphoinositide-dependent protein kinase 1	0	0	1	1
Mitogen-activated protein kinase kinase kinase 13	0	0	1	1
Death-associated protein kinase 3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 7	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 2	0	0	1	1
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	1	1
NUAK family SNF1-like kinase 1	0	0	1	1
Dynamin-like 120 kDa protein, mitochondrial	0	0	1	1
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	0	0	1	1
Tyrosine-protein kinase JAK2	0	1	1	2
Eukaryotic translation initiation factor 5B	0	0	1	1
Rho-associated protein kinase 2	0	0	1	1
Serine/threonine-protein kinase ULK1	0	0	1	1
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	1	1
Ribosomal protein S6 kinase alpha-5	0	0	1	1
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	1	1
Ribosomal protein S6 kinase alpha-4	0	0	1	1
Serine/threonine-protein kinase 16	0	0	1	1
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	0	0	1	1
Serine/threonine-protein kinase PAK 3	0	0	1	1
Cyclin-dependent kinase-like 5	0	0	1	1
Serine/threonine-protein kinase 17B	0	0	1	1
Serine/threonine-protein kinase 10	0	0	1	1
Serine/threonine-protein kinase D3	0	0	1	1
Cyclin-dependent kinase 14	0	0	1	1
Structural maintenance of chromosomes protein 2	0	0	1	1
Mitogen-activated protein kinase kinase kinase 6	0	0	1	1
Sodium-dependent phosphate transport protein 2B	0	1	0	1
Serine/threonine-protein kinase OSR1	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	1	1
Serine/threonine-protein kinase LATS1	0	0	1	1
Serine/threonine-protein kinase PAK 4	0	0	1	1
Serine/threonine-protein kinase Chk2	0	0	1	1
Tyrosine-protein kinase ABL1	0	1	1	2
Tyrosine-protein kinase ABL1	0	1	0	1
Epidermal growth factor receptor	0	1	1	2
HLA class I histocompatibility antigen, B alpha chain	2	0	0	2
RAF proto-oncogene serine/threonine-protein kinase	0	0	1	1
HLA class II histocompatibility antigen gamma chain	0	1	0	1
Receptor tyrosine-protein kinase erbB-2	0	1	1	2
High affinity nerve growth factor receptor	0	1	1	2
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	1	1
ADP/ATP translocase 2	0	0	1	1
Protein kinase C beta type	0	0	1	1
Insulin receptor	0	1	1	2
Tyrosine-protein kinase Lck	0	1	1	2
Tyrosine-protein kinase Fyn	0	1	1	2
Cyclin-dependent kinase 1	0	1	1	2
Glycogen phosphorylase, liver form	0	0	1	1
Nucleophosmin	0	1	0	1
Tyrosine-protein kinase Fes/Fps	0	0	1	1
Macrophage colony-stimulating factor 1 receptor	0	1	1	2
Adenine phosphoribosyltransferase	0	0	1	1
Tyrosine-protein kinase Yes	0	0	1	1
Tyrosine-protein kinase Lyn	0	0	1	1
Proto-oncogene tyrosine-protein kinase receptor Ret	0	1	1	2
Insulin-like growth factor 1 receptor	0	1	1	2
Signal recognition particle receptor subunit alpha	0	0	1	1
Cytochrome c1, heme protein, mitochondrial	0	0	1	1
Hepatocyte growth factor receptor	0	2	1	3
Tyrosine-protein kinase HCK	0	0	1	1
Proto-oncogene tyrosine-protein kinase ROS	0	2	1	3
Platelet-derived growth factor receptor beta	0	1	1	2
Tyrosine-protein kinase Fgr	0	1	1	2
Wee1-like protein kinase 2	0	0	1	1
Uncharacterized serine/threonine-protein kinase SBK3	0	0	1	1
Androgen receptor	0	3	0	3
Serine/threonine-protein kinase A-Raf	0	0	1	1
Mast/stem cell growth factor receptor Kit	0	0	1	1
Glycogen phosphorylase, brain form	0	0	1	1
Breakpoint cluster region protein	0	0	1	1
Serine/threonine-protein kinase pim-1	0	0	1	1
Fibroblast growth factor receptor 1	0	1	1	2
Cyclin-dependent kinase 4	0	0	1	1
ADP/ATP translocase 3	0	0	1	1
Inosine-5'-monophosphate dehydrogenase 2	0	0	1	1
Proto-oncogene tyrosine-protein kinase Src	0	1	1	2
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	1	1
Insulin receptor-related protein	0	0	1	1
G2/mitotic-specific cyclin-B1	0	1	0	1
Serine/threonine-protein kinase B-raf	0	0	1	1
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	1	1
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	0	1	1
Platelet-derived growth factor receptor alpha	0	1	1	2
Tyrosine-protein kinase Fer	0	0	1	1
Protein kinase C alpha type	0	0	1	1
cAMP-dependent protein kinase catalytic subunit alpha	0	0	1	1
Vascular endothelial growth factor receptor 1	0	1	1	2
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	1	1
Interferon-induced, double-stranded RNA-activated protein kinase	0	0	1	1
Casein kinase II subunit alpha'	0	0	1	1
Ras-related protein Rab-6A	0	0	1	1
Serine/threonine-protein kinase MAK	0	0	1	1
Cyclin-dependent kinase 11B	0	0	1	1
Ephrin type-A receptor 1	0	0	1	1
Fibroblast growth factor receptor 2	0	0	1	1
Receptor tyrosine-protein kinase erbB-3	0	0	1	1
Multifunctional protein ADE2	0	0	1	1
Fibroblast growth factor receptor 4	0	0	1	1
Fibroblast growth factor receptor 3	0	1	1	2
cAMP-dependent protein kinase catalytic subunit gamma	0	0	1	1
cAMP-dependent protein kinase catalytic subunit beta	0	0	1	1
Ferrochelatase, mitochondrial	0	0	1	1
Ribosomal protein S6 kinase beta-1	0	1	1	2
Tyrosine-protein kinase JAK1	0	1	1	2
Protein kinase C eta type	0	0	1	1
Cyclin-dependent kinase 2	0	0	1	1
Beta-adrenergic receptor kinase 1	0	0	1	1
Probable ATP-dependent RNA helicase DDX6	0	0	1	1
Activin receptor type-2A	0	0	1	1
Mitogen-activated protein kinase 3	0	0	1	1
MAP/microtubule affinity-regulating kinase 3	0	0	1	1
Deoxycytidine kinase	0	0	1	1
Mitogen-activated protein kinase 1	0	0	1	1
Ephrin type-A receptor 2	0	1	1	2
Ephrin type-A receptor 3	0	0	1	1
Ephrin type-A receptor 8	0	0	1	1
Ephrin type-B receptor 2	0	1	1	2
Leukocyte tyrosine kinase receptor	0	0	1	1
Non-receptor tyrosine-protein kinase TYK2	0	1	1	2
UMP-CMP kinase	0	0	1	1
Phosphatidylethanolamine-binding protein 1	0	0	1	1
Wee1-like protein kinase	0	0	1	1
Heme oxygenase 2	0	0	1	1
Tyrosine-protein kinase receptor UFO	0	1	1	2
Mitogen-activated protein kinase 4	0	0	1	1
S-adenosylmethionine synthase isoform type-2	0	0	1	1
DnaJ homolog subfamily A member 1	0	0	1	1
RAC-alpha serine/threonine-protein kinase	0	0	1	1
RAC-beta serine/threonine-protein kinase	0	1	1	2
G protein-coupled receptor kinase 4	0	0	1	1
Dual specificity protein kinase TTK	0	0	1	1
DNA replication licensing factor MCM4	0	0	1	1
Myosin-10	0	0	1	1
Tyrosine-protein kinase receptor Tie-1	0	0	1	1
Vascular endothelial growth factor receptor 3	0	0	1	1
Vascular endothelial growth factor receptor 2	0	1	1	2
Dual specificity mitogen-activated protein kinase kinase 2	0	0	1	1
Receptor-type tyrosine-protein kinase FLT3	0	1	1	2
Bone morphogenetic protein receptor type-1A	0	0	1	1
Activin receptor type-1B	0	0	1	1
TGF-beta receptor type-1	0	0	1	1
Serine/threonine-protein kinase receptor R3	0	0	1	1
TGF-beta receptor type-2	0	0	1	1
Electron transfer flavoprotein subunit beta	0	0	1	1
Tyrosine-protein kinase CSK	0	0	1	1
Glycine--tRNA ligase	0	0	1	1
Protein kinase C iota type	0	0	1	1
Exosome RNA helicase MTR4	0	0	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	0	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	0	1	1
Serine/threonine-protein kinase mTOR	0	0	1	1
Megakaryocyte-associated tyrosine-protein kinase	0	0	1	1
Tyrosine-protein kinase Tec	0	0	1	1
Tyrosine-protein kinase TXK	0	0	1	1
Tyrosine-protein kinase ABL2	0	0	1	1
Tyrosine-protein kinase FRK	0	0	1	1
G protein-coupled receptor kinase 6	0	0	1	1
Tyrosine-protein kinase ZAP-70	0	0	1	1
Tyrosine-protein kinase SYK	0	0	1	1
26S proteasome regulatory subunit 6B	0	0	1	1
Mitogen-activated protein kinase 8	0	0	1	1
Mitogen-activated protein kinase 9	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 4	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 3	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	1	1
Casein kinase I isoform alpha	0	0	1	1
Casein kinase I isoform delta	0	0	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	0	1	1
MAP kinase-activated protein kinase 2	0	0	1	1
Cyclin-dependent kinase 8	0	0	1	1
Elongation factor Tu, mitochondrial	0	0	1	1
Choline-phosphate cytidylyltransferase A	0	0	1	1
Cysteine--tRNA ligase, cytoplasmic	0	0	1	1
Casein kinase I isoform epsilon	0	0	1	1
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	1	1
Dual specificity protein kinase CLK1	0	0	1	1
Dual specificity protein kinase CLK2	0	0	1	1
Dual specificity protein kinase CLK3	0	0	1	1
Glycogen synthase kinase-3 alpha	0	0	1	1
Glycogen synthase kinase-3 beta	0	0	1	1
Cyclin-dependent kinase 7	0	1	1	2
Cyclin-dependent kinase 9	0	0	1	1
Ras-related protein Rab-27A	0	0	1	1
Tyrosine-protein kinase Blk	0	0	1	1
Interleukin-1 receptor-associated kinase 1	0	0	1	1
Ribosomal protein S6 kinase alpha-3	0	0	1	1
Cytoplasmic tyrosine-protein kinase BMX	0	1	1	2
cAMP-dependent protein kinase catalytic subunit PRKX	0	0	1	1
Serine/threonine-protein kinase Nek2	0	0	1	1
Serine/threonine-protein kinase Nek3	0	0	1	1
Serine/threonine-protein kinase Nek4	0	0	1	1
Tyrosine-protein kinase JAK3	0	1	1	2
Dual specificity mitogen-activated protein kinase kinase 6	0	0	1	1
Serine/threonine-protein kinase PLK1	0	0	1	1
Death-associated protein kinase 1	0	0	1	1
LIM domain kinase 1	0	0	1	1
LIM domain kinase 2	0	0	1	1
Mitogen-activated protein kinase 12	0	0	1	1
Mitogen-activated protein kinase 10	0	0	1	1
Tyrosine--tRNA ligase, cytoplasmic	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	1	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	1	1
Ephrin type-B receptor 3	0	0	1	1
Ephrin type-A receptor 5	0	0	1	1
Ephrin type-B receptor 4	0	1	1	2
Ephrin type-B receptor 1	0	0	1	1
Ephrin type-A receptor 4	0	0	1	1
Adenylate kinase 2, mitochondrial	0	0	1	1
Adenosine kinase	0	0	1	1
Hormonally up-regulated neu tumor-associated kinase	0	0	1	1
Serine/threonine-protein kinase SIK1	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 4	0	0	1	1
Ras-related protein Rab-10	0	0	1	1
Cell division control protein 2 homolog	0	0	1	1
Actin-related protein 3	0	0	1	1
Actin-related protein 2	0	0	1	1
Calcium-dependent protein kinase 1	0	0	1	1
GTP-binding nuclear protein Ran	0	0	1	1
Casein kinase II subunit alpha	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	0	0	1	1
SRSF protein kinase 2	0	0	1	1
Casein kinase I isoform gamma-2	0	0	1	1
Mitogen-activated protein kinase kinase kinase 9	0	0	1	1
ALK tyrosine kinase receptor	0	1	0	1
Serine/threonine-protein kinase PknB	0	0	1	1
Cyclin-dependent kinase 3	0	0	1	1
Cyclin-dependent kinase-like 1	0	0	1	1
Cyclin-dependent kinase 6	0	0	1	1
Cyclin-dependent-like kinase 5	0	0	1	1
Cyclin-dependent kinase 16	0	0	1	1
Cyclin-dependent kinase 17	0	0	1	1
ATP-dependent 6-phosphofructokinase, platelet type	0	0	1	1
Protein kinase C epsilon type	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 1	0	0	1	1
Angiopoietin-1 receptor	0	1	1	2
Mitogen-activated protein kinase kinase kinase 10	0	0	1	1
Angiopoietin-1 receptor	0	1	0	1
DNA topoisomerase 2-beta	0	0	1	1
Protein kinase C theta type	0	0	1	1
Activin receptor type-1	0	0	1	1
Macrophage-stimulating protein receptor	0	1	1	2
Focal adhesion kinase 1	0	0	1	1
Protein kinase C delta type	0	0	1	1
Tyrosine-protein kinase BTK	0	1	1	2
Tyrosine-protein kinase receptor TYRO3	0	1	1	2
Cyclin-dependent kinase 18	0	0	1	1
Activated CDC42 kinase 1	0	0	1	1
Epithelial discoidin domain-containing receptor 1	0	0	1	1
Tyrosine-protein kinase ITK/TSK	0	0	1	1
Myotonin-protein kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	1	1
Mitogen-activated protein kinase kinase kinase 12	0	0	1	1
Tyrosine-protein kinase Mer	0	1	1	2
Serine/threonine-protein kinase 4	0	0	1	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	1	1
Serine/threonine-protein kinase PAK 1	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 5	0	0	1	1
Mitogen-activated protein kinase 7	0	0	1	1
Serine/threonine-protein kinase PAK 2	0	0	1	1
Serine/threonine-protein kinase 3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 1	0	0	1	1
cGMP-dependent protein kinase 2	0	0	1	1
Integrin-linked protein kinase	0	0	1	1
Rho-associated protein kinase 1	0	0	1	1
Non-receptor tyrosine-protein kinase TNK1	0	0	1	1
Serine/threonine-protein kinase PRP4 homolog	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 1	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	1	1
Activin receptor type-2B	0	0	1	1
Bone morphogenetic protein receptor type-2	0	0	1	1
Protein-tyrosine kinase 6	0	0	1	1
cGMP-dependent protein kinase 1	0	0	1	1
Cyclin-dependent kinase 13	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1	0	0	1	1
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	1	1
Protein-tyrosine kinase 2-beta	0	0	1	1
Maternal embryonic leucine zipper kinase	0	0	1	1
Structural maintenance of chromosomes protein 1A	0	0	1	1
Chromodomain-helicase-DNA-binding protein 4	0	0	1	1
Lysine--tRNA ligase	0	1	0	1
Peroxisomal acyl-coenzyme A oxidase 1	0	0	1	1
Cyclin-dependent kinase 10	0	0	1	1
Serine/threonine-protein kinase D1	0	1	1	2
Serine/threonine-protein kinase 38	0	0	1	1
Receptor tyrosine-protein kinase erbB-4	0	0	1	1
Ribosomal protein S6 kinase alpha-2	0	0	1	1
Ephrin type-A receptor 7	0	0	1	1
Delta(24)-sterol reductase	0	0	1	1
Ribosomal protein S6 kinase alpha-1	0	0	1	1
Dual specificity testis-specific protein kinase 1	0	0	1	1
Myosin light chain kinase, smooth muscle	0	0	1	1
Mitogen-activated protein kinase 11	0	0	1	1
Serine/threonine-protein kinase STK11	0	0	1	1
Rhodopsin kinase GRK1	0	0	1	1
NT-3 growth factor receptor	0	0	1	1
Serine/threonine-protein kinase N1	0	0	1	1
Serine/threonine-protein kinase N2	0	1	1	2
Mitogen-activated protein kinase 14	0	1	1	2
Calcium/calmodulin-dependent protein kinase type IV	0	0	1	1
Mitogen-activated protein kinase kinase kinase 11	0	0	1	1
BDNF/NT-3 growth factors receptor	0	1	1	2
Mitogen-activated protein kinase 6	0	0	1	1
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	0	0	1	1
Discoidin domain-containing receptor 2	0	0	1	1
AP2-associated protein kinase 1	0	0	1	1
Myosin light chain kinase 3	0	0	1	1
Uncharacterized aarF domain-containing protein kinase 5	0	0	1	1
Serine/threonine-protein kinase SBK1	0	0	1	1
Mitogen-activated protein kinase kinase kinase 19	0	0	1	1
Putative heat shock protein HSP 90-beta 2	0	0	1	1
Serine/threonine-protein kinase TNNI3K	0	0	1	1
Rab-like protein 3	0	0	1	1
Leucine-rich repeat serine/threonine-protein kinase 2	0	0	1	1
Sigma intracellular receptor 2	0	1	0	1
Serine/threonine-protein kinase MRCK alpha	0	0	1	1
Macrophage-stimulating protein receptor	0	1	0	1
Serine/threonine-protein kinase MRCK gamma	0	0	1	1
Acyl-CoA dehydrogenase family member 10	0	0	1	1
Serine/threonine-protein kinase Nek5	0	0	1	1
Serine/threonine-protein kinase N3	0	0	1	1
Serine/threonine-protein kinase ULK3	0	0	1	1
Dual serine/threonine and tyrosine protein kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 15	0	0	1	1
Uncharacterized protein FLJ45252	0	0	1	1
Acyl-CoA dehydrogenase family member 11	0	0	1	1
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	1	1
Serine/threonine-protein kinase MARK2	0	0	1	1
ATP-dependent RNA helicase DHX30	0	0	1	1
Serine/threonine-protein kinase TAO1	0	0	1	1
STE20-related kinase adapter protein alpha	0	0	1	1
Myosin-14	0	0	1	1
AarF domain-containing protein kinase 1	0	0	1	1
Serine/threonine-protein kinase tousled-like 2	0	0	1	1
Serine/threonine-protein kinase 32C	0	0	1	1
Serine/threonine-protein kinase pim-3	0	0	1	1
ATP-dependent RNA helicase DDX42	0	0	1	1
Serine/threonine-protein kinase VRK2	0	0	1	1
Myosin light chain kinase family member 4	0	0	1	1
Homeodomain-interacting protein kinase 1	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1D	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 3	0	1	1	2
Cyclin-dependent kinase-like 3	0	0	1	1
MAP kinase-activated protein kinase 5	0	0	1	1
Serine/threonine-protein kinase BRSK2	0	0	1	1
Serine/threonine-protein kinase NIM1	0	0	1	1
Serine/threonine-protein kinase ULK2	0	0	1	1
Misshapen-like kinase 1	0	0	1	1
Serine/threonine-protein kinase DCLK2	0	0	1	1
Calcium/calmodulin-dependent protein kinase kinase 1	0	0	1	1
Casein kinase I isoform alpha-like	0	0	1	1
Mixed lineage kinase domain-like protein	0	0	1	1
Homeodomain-interacting protein kinase 4	0	0	1	1
Myosin-IIIa	0	0	1	1
Ankyrin repeat and protein kinase domain-containing protein 1	0	0	1	1
Serine/threonine-protein kinase Nek11	0	0	1	1
Atypical kinase COQ8A, mitochondrial	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	1	1
Mitogen-activated protein kinase 15	0	0	1	1
Serine/threonine-protein kinase Nek9	0	0	1	1
Serine/threonine-protein kinase BRSK1	0	0	1	1
Serine/threonine-protein kinase 35	0	0	1	1
Serine/threonine-protein kinase Nek7	0	0	1	1
Rhodopsin kinase GRK7	0	0	1	1
Serine/threonine-protein kinase 32A	0	0	1	1
Myosin-IIIb	0	0	1	1
ATP-dependent RNA helicase DDX1	0	0	1	1
Inositol hexakisphosphate kinase 1	2	0	0	2
Dual specificity tyrosine-phosphorylation-regulated kinase 2	0	0	1	1
Cyclin-dependent kinase-like 2	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	1	1
Serine/threonine-protein kinase Sgk3	0	0	1	1
Atypical kinase COQ8B, mitochondrial	0	0	1	1
Aurora kinase B	0	0	1	1
MAP/microtubule affinity-regulating kinase 4	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1G	0	0	1	1
Serine/threonine-protein kinase Nek1	0	0	1	1
Cyclin-dependent kinase 15	0	0	1	1
PAS domain-containing serine/threonine-protein kinase	0	0	1	1
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	1	1
EKC/KEOPS complex subunit TP53RK	0	0	1	1
Dual specificity testis-specific protein kinase 2	0	0	1	1
SRSF protein kinase 1	0	0	1	1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 5	0	0	1	1
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	0	0	1	1
Mitogen-activated protein kinase kinase kinase 3	0	0	1	1
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	1	1
Serine/threonine-protein kinase RIO1	0	0	1	1
MAP kinase-interacting serine/threonine-protein kinase 1	0	0	1	1
Serine/threonine-protein kinase RIO2	0	0	1	1
Cyclin-dependent kinase 19	0	0	1	1
Transient receptor potential cation channel subfamily M member 6	0	0	1	1
Testis-specific serine/threonine-protein kinase 1	0	0	1	1
Serine/threonine-protein kinase 33	0	0	1	1
Nucleolar GTP-binding protein 1	0	0	1	1
Serine/threonine-protein kinase D2	0	0	1	1
Serine/threonine-protein kinase DCLK3	0	0	1	1
NUAK family SNF1-like kinase 2	0	0	1	1
RNA cytidine acetyltransferase	0	0	1	1
Serine/threonine-protein kinase SIK2	0	0	1	1
Myosin light chain kinase 2, skeletal/cardiac muscle	0	0	1	1
STE20-like serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase TAO3	0	0	1	1
Homeodomain-interacting protein kinase 2	0	0	1	1
Tyrosine-protein kinase Srms	0	0	1	1
Homeodomain-interacting protein kinase 3	0	0	1	1
Serine/threonine-protein kinase PLK3	0	0	1	1
dCTP pyrophosphatase 1	0	0	1	1
Dual specificity protein kinase CLK4	0	0	1	1
MAP kinase-interacting serine/threonine-protein kinase 2	0	0	1	1
Echinoderm microtubule-associated protein-like 4	0	1	0	1
Serine/threonine-protein kinase Nek6	0	0	1	1
Casein kinase I isoform gamma-1	0	0	1	1
Serine/threonine-protein kinase PAK 6	0	0	1	1
SNF-related serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase LATS2	0	0	1	1
Serine/threonine-protein kinase 36	0	0	1	1
Phenylalanine--tRNA ligase beta subunit	0	0	1	1
Isoleucine--tRNA ligase, mitochondrial	0	0	1	1
BMP-2-inducible protein kinase	0	0	1	1
Obg-like ATPase 1	0	0	1	1
Midasin	0	0	1	1
Aurora kinase A-interacting protein	0	1	0	1
Interleukin-1 receptor-associated kinase 4	0	0	1	1
Serine/threonine-protein kinase 32B	0	0	1	1
Mitogen-activated protein kinase kinase kinase 20	0	0	1	1
Cyclin-dependent kinase 12	0	0	1	1
Serine/threonine-protein kinase PLK2	0	0	1	1
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	1	1
Serine/threonine-protein kinase MARK1	0	0	1	1
Serine/threonine-protein kinase pim-2	0	0	1	1
Serine/threonine-protein kinase PAK 5	0	0	1	1
Serine/threonine-protein kinase 26	0	0	1	1
eIF-2-alpha kinase GCN2	0	0	1	1
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	1	1
Serine/threonine-protein kinase NLK	0	0	1	1
Phosphatidylinositol 4-kinase beta	0	0	1	1
Serine/threonine-protein kinase 17A	0	0	1	1
STE20/SPS1-related proline-alanine-rich protein kinase	0	0	1	1
Ephrin type-A receptor 6	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	1	1
Serine/threonine-protein kinase TBK1	0	0	1	1
Septin-9	0	0	1	1
Death-associated protein kinase 2	0	0	1	1
Ribosomal protein S6 kinase alpha-6	0	0	1	1
TRAF2 and NCK-interacting protein kinase	0	0	1	1
Serine/threonine-protein kinase tousled-like 1	0	0	1	1
Serine/threonine-protein kinase TAO2	0	0	1	1
Long-chain-fatty-acid--CoA ligase 5	0	0	1	1
ALK tyrosine kinase receptor	0	3	2	5
SRSF protein kinase 3	0	0	1	1
Serine/threonine-protein kinase ICK	0	0	1	1
Cyclin-dependent kinase 11A	0	0	1	1
Aurora kinase C	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	0	1	1
RAC-gamma serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase 38-like	0	0	1	1
Microtubule-associated serine/threonine-protein kinase 1	0	0	1	1
Serine/threonine-protein kinase SIK3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 2	0	0	1	1
Thyroid hormone receptor-associated protein 3	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 3	0	0	1	1
Serine/threonine-protein kinase MRCK beta	0	0	1	1
Interleukin-1 receptor-associated kinase 3	0	0	1	1
Serine/threonine-protein kinase 24	0	0	1	1
Casein kinase I isoform gamma-3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 4	0	0	1	1
cytochrome P450 2C9, partial	2	0	0	2
Menin	0	0	1	1
Lecithin retinol acyltransferase	0	1	0	1
30S ribosomal protein S6	0	1	0	1
30S ribosomal protein S7	0	1	0	1
50S ribosomal protein L15	0	1	0	1
50S ribosomal protein L10	0	1	0	1
50S ribosomal protein L11	0	1	0	1
50S ribosomal protein L7/L12	0	1	0	1
50S ribosomal protein L19	0	1	0	1
50S ribosomal protein L1	0	1	0	1
50S ribosomal protein L20	0	1	0	1
50S ribosomal protein L27	0	1	0	1
50S ribosomal protein L28	0	1	0	1
50S ribosomal protein L29	0	1	0	1
50S ribosomal protein L31	0	1	0	1
50S ribosomal protein L31 type B	0	1	0	1
50S ribosomal protein L32	0	1	0	1
50S ribosomal protein L33	0	1	0	1
50S ribosomal protein L34	0	1	0	1
50S ribosomal protein L35	0	1	0	1
50S ribosomal protein L36	0	1	0	1
30S ribosomal protein S10	0	1	0	1
30S ribosomal protein S11	0	1	0	1
30S ribosomal protein S12	0	1	0	1
30S ribosomal protein S13	0	1	0	1
30S ribosomal protein S16	0	1	0	1
30S ribosomal protein S18	0	1	0	1
30S ribosomal protein S19	0	1	0	1
30S ribosomal protein S20	0	1	0	1
30S ribosomal protein S2	0	1	0	1
30S ribosomal protein S3	0	1	0	1
30S ribosomal protein S4	0	1	0	1
30S ribosomal protein S5	0	1	0	1
30S ribosomal protein S8	0	1	0	1
30S ribosomal protein S9	0	1	0	1
50S ribosomal protein L13	0	1	0	1
50S ribosomal protein L14	0	1	0	1
50S ribosomal protein L16	0	1	0	1
50S ribosomal protein L23	0	1	0	1
30S ribosomal protein S15	0	1	0	1
50S ribosomal protein L17	0	1	0	1
50S ribosomal protein L21	0	1	0	1
50S ribosomal protein L30	0	1	0	1
50S ribosomal protein L6	0	1	0	1
30S ribosomal protein S14	0	1	0	1
30S ribosomal protein S17	0	1	0	1
30S ribosomal protein S1	0	1	0	1
50S ribosomal protein L18	0	1	0	1
Lethal factor	0	1	0	1
50S ribosomal protein L2	0	1	0	1
50S ribosomal protein L3	0	1	0	1
50S ribosomal protein L24	0	1	0	1
50S ribosomal protein L4	0	1	0	1
50S ribosomal protein L22	0	1	0	1
50S ribosomal protein L5	0	1	0	1
30S ribosomal protein S21	0	1	0	1
50S ribosomal protein L25	0	1	0	1
50S ribosomal protein L36 2	0	1	0	1
Protein Rev	0	0	1	1
Aminoglycoside 3'-phosphotransferase	0	0	0	1
Tyrosyl-DNA phosphodiesterase 1	0	1	0	1
SMAD family member 2	1	0	0	1
SMAD family member 3	1	0	0	1
nuclear receptor subfamily 1, group I, member 3	2	0	0	2
farnesoid X nuclear receptor	3	0	0	3
flap endonuclease 1	3	0	0	3
geminin	6	0	0	6
Rap guanine nucleotide exchange factor 3	1	0	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	1	0	0	1
thioredoxin reductase	2	0	0	2
Replicase polyprotein 1ab	0	1	0	1
CAAX prenyl protease 2 isoform 2	0	0	0	1
DNA polymerase beta	1	0	0	1
histone acetyltransferase KAT2A isoform 1	2	0	0	2
streptokinase A precursor	0	0	2	2
Bile salt export pump	0	1	0	1
Tubulin beta-4A chain	0	1	0	1
Tubulin beta chain	0	1	0	1
ATP-dependent translocase ABCB1	0	0	0	1
Tubulin alpha-3C chain	0	1	0	1
Spike glycoprotein	2	0	0	2
Tubulin alpha-1B chain	0	1	0	1
Tubulin alpha-4A chain	0	1	0	1
Tubulin beta-4B chain	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
DNA primase	0	1	0	1
Tubulin beta-3 chain	0	1	0	1
Tubulin beta-2A chain	0	1	0	1
Tubulin beta-8 chain	0	1	0	1
Tubulin alpha-3E chain	0	1	0	1
Tubulin alpha-1A chain	0	1	0	1
Multidrug and toxin extrusion protein 1	0	1	0	1
Tubulin alpha-1C chain	0	1	0	1
Tubulin beta-6 chain	0	1	0	1
Tubulin beta-2B chain	0	1	0	1
Tubulin beta-1 chain	0	1	0	1
Chain A, Ferritin light chain	2	0	0	2
arylsulfatase A	2	0	0	2
STE24	0	0	0	1
nuclear factor erythroid 2-related factor 2 isoform 2	3	0	0	3
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	1	0	0	1
CAAX prenyl protease	0	0	0	1
Trypsin	0	0	0	1
Albumin	0	0	1	1
endonuclease IV	3	0	0	3
RAR-related orphan receptor gamma	4	0	0	4
USP1 protein, partial	1	0	0	1
GALC protein	1	0	0	1
GLI family zinc finger 3	4	0	0	4
thyroid stimulating hormone receptor	2	0	0	2
estrogen receptor 2 (ER beta)	3	0	0	3
nonstructural protein 1	1	0	0	1
estrogen nuclear receptor alpha	5	0	0	5
peroxisome proliferator-activated receptor delta	1	0	0	1
Bloom syndrome protein isoform 1	3	0	0	3
cytochrome P450 2C19 precursor	2	0	0	2
potassium voltage-gated channel subfamily H member 2 isoform d	1	0	0	1
thyroid hormone receptor beta isoform 2	3	0	0	3
peripheral myelin protein 22	1	0	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	1	0	0	1
Cellular tumor antigen p53	3	0	0	3
ATPase family AAA domain-containing protein 5	2	0	0	2
Ataxin-2	2	0	0	2
Chain A, Beta-lactamase	1	0	0	1
regulator of G-protein signaling 4	1	0	0	1
retinoic acid nuclear receptor alpha variant 1	2	0	0	2
retinoid X nuclear receptor alpha	2	0	0	2
estrogen-related nuclear receptor alpha	3	0	0	3
pregnane X nuclear receptor	3	0	0	3
Parkin	1	0	0	1
peroxisome proliferator activated receptor gamma	1	0	0	1
vitamin D (1,25- dihydroxyvitamin D3) receptor	1	0	0	1
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	2	0	0	2
thyroid stimulating hormone receptor	1	0	0	1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	1	0	0	1
prostaglandin E2 receptor EP2 subtype	0	0	0	1
DNA polymerase iota isoform a (long)	1	0	0	1
neuropeptide S receptor isoform A	1	0	0	1
Translocator protein	0	2	1	3
5-hydroxytryptamine receptor 1A	0	0	1	1
Translocator protein	0	2	1	4
Nuclear receptor subfamily 1 group I member 3	0	1	0	1
luciferase	0	0	0	1
hypoxia-inducible factor 1 alpha subunit	1	0	0	1
progesterone receptor	2	0	0	2
aryl hydrocarbon receptor	1	0	0	1
v-jun sarcoma virus 17 oncogene homolog (avian)	1	0	0	1
nuclear receptor subfamily 1, group I, member 2	1	0	0	1
Voltage-dependent calcium channel gamma-2 subunit	1	0	0	1
Fatty acid-binding protein, liver	0	1	0	1
Estrogen receptor	0	2	0	2
Glucocorticoid receptor	0	2	1	8
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Glycine receptor subunit alpha-1	0	2	0	2
Corticosteroid-binding globulin	0	1	0	1
Mineralocorticoid receptor	0	2	1	3
Glutamine synthetase	0	0	1	1
Androgen receptor	0	1	0	1
Glutamate receptor 2	1	0	0	1
Glycine receptor subunit beta	0	2	0	2
Glycine receptor subunit alpha-2	0	2	0	2
Glycine receptor subunit alpha-3	0	2	0	2
Histamine H1 receptor	0	0	1	1
Nociceptin receptor	0	0	1	1
Cytochrome P450 2J2	0	2	0	2
Estrogen receptor beta	0	2	0	2
interleukin 8	2	0	0	2
activating transcription factor 6	1	0	0	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	1	0	0	1
exodeoxyribonuclease V subunit RecD	0	1	0	1
exodeoxyribonuclease V subunit RecB	0	1	0	1
exodeoxyribonuclease V subunit RecC	0	1	0	1
ATP-dependent 6-phosphofructokinase	0	1	0	1
Dihydropteroate synthase	0	1	0	1
5-hydroxytryptamine receptor 2A	0	2	0	2
Dihydrofolate reductase	0	3	0	4
Endothelin-1 receptor	0	1	0	1
Protease	0	1	1	2
Chain A, Dihydrofolate Reductase	0	0	1	1
Chain A, Dihydrofolate reductase	0	1	0	1
Chain A, dihydrofolate reductase (DHFR)	0	1	0	1
Chain A, Dihydrofolate reductase	0	1	0	1
Chain A, Dihydrofolate reductase	0	1	0	1
acetylcholinesterase	1	0	0	1
dopamine D1 receptor	1	0	0	1
ATAD5 protein, partial	1	0	0	1
NFKB1 protein, partial	1	0	0	1
67.9K protein	1	0	0	1
cytochrome P450 3A4 isoform 1	1	0	0	1
muscarinic acetylcholine receptor M1	1	0	0	1
lethal factor (plasmid)	1	0	0	1
Solute carrier family 22 member 1	0	1	0	1
Dihydrofolate reductase	0	1	0	2
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase type 1	0	1	0	2
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Dihydrofolate reductase	0	1	0	1
NH(3)-dependent NAD(+) synthetase	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Dihydrofolate reductase type 1 from Tn4003	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
5-hydroxytryptamine receptor 2B	0	1	0	1
Metabotropic glutamate receptor 5	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Trace amine-associated receptor 5	0	0	1	1
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	2
Dihydrofolate reductase	0	1	0	1
Sterol 14-alpha-demethylase	0	0	1	1
14-alpha sterol demethylase	0	0	1	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Cholesterol side-chain cleavage enzyme, mitochondrial	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
Cytochrome P450 2B6	0	1	0	1
Cytochrome P450 144	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Sterol 14-alpha demethylase	0	0	1	1
14-alpha sterol demethylase	0	0	1	1
14-alpha sterol demethylase	0	0	1	1
Cholesterol 24-hydroxylase	0	2	1	3
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Pyelonephritis, Xanthogranulomatous

Synonyms(2)

Research Excerpts

Overview

Treatment

Research

Studies (34)

Protein Targets (860)

Pyelonephritis, Xanthogranulomatous

Synonyms(2)

Research Excerpts

Overview

Treatment

Research

Studies (34)

Drugs Studied (29)

Protein Targets (860)