Pseudoxanthoma Elasticum

An inherited disorder of connective tissue with extensive degeneration and calcification of ELASTIC TISSUE primarily in the skin, eye, and vasculature. At least two forms exist, autosomal recessive and autosomal dominant. This disorder is caused by mutations of one of the ATP-BINDING CASSETTE TRANSPORTERS. Patients are predisposed to MYOCARDIAL INFARCTION and GASTROINTESTINAL HEMORRHAGE.

Synonym
Pseudoxanthoma Elasticum

Excerpt	Reference
"Pseudoxanthoma elasticum is a genetic disease characterized by progressive mineralization of elastic fibers."	( Baccarani Contri, M; Cingi, MR; De Luca, G; Pasquali Ronchetti, I; Rindi, S; Salvini, R; Tiozzo Costa, R, 1988)
"Pseudoxanthoma elasticum is a rare inherited disorder of the elastic tissue characterised by multisystem manifestations."	( Brichant, JF; Chantraine, F; Clanet, M; Dewandre, PY; Foidart, JM; Peeters, P, 2011)
"Pseudoxanthoma elasticum is an inherited metabolic disorder resulting from ABCC6 gene mutations."	( Bergen, AA; Gorgels, TG; Grimaud, L; Henrion, D; Kauffenstein, G; Labat, C; Lacolley, P; Le Corre, Y; Le Saux, O; Lefthériotis, G; Martin, L; Mauras, Y; Pizard, A; Toutain, B; Vessières, E, 2014)
"Pseudoxanthoma elasticum is a prototype of heritable ectopic mineralization disorders, with phenotypic overlap with generalized arterial calcification of infancy and arterial calcification due to CD73 deficiency."	( Li, Q; Terry, SF; Uitto, J; van de Wetering, K; Váradi, A, 2017)
"Pseudoxanthoma elasticum is an autosomal recessive genodermatosis with variable expression, due to mutations in the ABCC6 or ENPP1 gene."	( Deianova, N; Nollet, L; Van Gils, M; Vanakker, OM; Verly, E, 2019)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	112 (35.78)	23.3326
1990's	37 (11.82)	12.5806
2000's	45 (14.38)	18.1394
2010's	88 (28.12)	28.8240
2020's	31 (9.90)	9.53

Drug	Relationship Strength	Studies	Trials
carbon monoxide	low	1	0
chlorine	low	1	0
cytosine	low	1	0
histamine	low	1	0
niacinamide	low	1	0
nitrates	low	4	0
diphosphoric acid	medium	15	1
thiosulfates	low	2	0
sulfites	low	1	0
thymine	low	1	0
phenytoin	low	1	0
acetaminophen	low	1	0
alendronate	low	2	0
aspirin	low	2	0
benzbromarone	low	2	0
bupivacaine	low	1	0
verapamil	low	1	0
chlorambucil	low	1	0
deferiprone	low	1	0
pentetic acid	low	1	0
dipyridamole	low	1	0
erythrosine	low	8	0
etidronate	medium	11	3
indomethacin	low	2	0
khellin	low	2	0
vitamin k 3	low	1	0
mesalamine	low	1	0
pentoxifylline	low	1	0
phenobarbital	low	1	0
4-phenylbutyric acid	low	2	0
probenecid	low	2	0
pyrimethamine	low	1	0
sodium fluoride	low	2	0
sulfamethazine	low	1	0
sulfamethoxazole	low	1	0
trientine	low	1	0
prednisolone	low	1	0
hydroxyproline	low	12	0
penicillamine	low	16	0
prednisone	low	1	0
isoflurophate	low	1	0
desoxycorticosterone acetate	low	1	0
glutamine	low	2	0
lysine	low	3	0
tubocurarine	low	1	0
galactose	low	1	0
edetic acid	low	2	0
tyrosine	low	1	0
adenosine monophosphate	low	2	0
cytarabine	low	1	0
alizarin	low	1	0
tryptophan	low	3	0
arginine	low	1	0
triamcinolone acetonide	low	1	0
isoprene	low	1	0
pantothenic acid	low	1	0
pyrroles	low	2	0
pyrazines	low	1	0
malondialdehyde	low	2	0
magnesium carbonate	low	1	0
isodesmosine	low	1	0
durapatite	low	1	0
d-alpha tocopherol	low	5	0
fluorescein	low	1	0
lanthanum	low	1	0
technetium	low	1	0
argon	low	1	0
potassium nitrate	low	2	0
tricalcium phosphate	low	4	0
sodium thiosulfate	low	2	0
trolamine salicylate	low	2	0
levamisole	low	1	0
cetylpyridinium chloride anhydrous	low	1	0
glutamic acid	low	1	0
sufentanil	low	1	0
propiconazole	low	1	0
atorvastatin	low	3	0
adenosine	low	4	0
glutathione disulfide	low	1	0
delphinidin	low	1	0
fluorodeoxyglucose f18	low	1	0
brinzolamide	low	1	0
pacein	low	1	0
fibrinogen	low	2	0
marimastat	low	1	0
proline	low	3	0
lanthanum carbonate	low	1	0
bortezomib	low	1	0
calcein am	low	1	0
fibrin	low	1	0
glucosamine	low	1	0
elastin	low	49	0
tretinoin	low	1	0
retinol	low	1	0
melphalan	low	1	0
pyrophosphate	medium	20	1
dermatan sulfate	medium	2	1
hydroxylysine	low	1	0
calcitriol	low	1	0
vitamin k semiquinone radical	low	14	0
leukotriene c4	low	1	0
cholecalciferol	low	1	0
isotretinoin	low	2	0
menaquinone 6	low	1	0
menaquinone 7	low	1	0
latanoprost	low	1	0
arsenic	low	1	0
sulfur	low	1	0
phosphorus	low	13	0
heroin	low	1	0
succinyl-trialanine-4-nitroanilide	low	1	0
verlukast	low	1	0
oxadiazoles	low	1	0
ptc 124	low	1	0
indocyanine green	low	14	0
pituitrin	low	1	0
acid phosphatase	low	1	0
desmosine	low	4	0
angiotensinogen	low	1	0
tannins	low	1	0
oligonucleotides	low	1	0
cellulose	low	1	0
endothelin-1	low	3	0
ro13-9904	low	1	0
cardiovascular agents	low	1	0
glycolipids	low	2	0
chondroitin	low	2	0
heparitin sulfate	low	2	0
ascorbic acid	low	1	0
warfarin	low	2	0
transforming growth factor beta	low	2	0
hyaluronoglucosaminidase	low	4	0
muramidase	low	1	0
chondroitin sulfates	low	3	0
guanine	low	2	0
folic acid	low	1	0
eye	low	16	0

Protein Targets (1,180)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	22	0	0	22
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
mitogen-activated protein kinase 1	10	0	0	10
survival motor neuron protein isoform d	19	0	0	19
Histone deacetylase 3	0	3	0	3
Histone deacetylase 4	0	2	0	2
Histone deacetylase 1	0	4	0	4
Histone deacetylase 7	0	2	0	2
Histone deacetylase 2	0	4	0	4
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 11	0	1	0	1
Histone deacetylase 8	0	3	0	3
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	2	0	2
Histone deacetylase 6	0	4	0	4
Histone deacetylase 9	0	2	0	2
Histone deacetylase 5	0	2	0	2
RAR-related orphan receptor gamma	35	0	0	35
ATAD5 protein, partial	8	0	0	8
GLS protein	14	0	0	14
Microtubule-associated protein tau	24	0	0	24
Smad3	6	0	0	6
aldehyde dehydrogenase 1 family, member A1	28	0	0	28
thyroid stimulating hormone receptor	14	0	0	14
nuclear receptor subfamily 1, group I, member 3	24	0	0	24
progesterone receptor	22	0	0	22
EWS/FLI fusion protein	16	0	0	16
retinoic acid nuclear receptor alpha variant 1	34	0	0	34
retinoid X nuclear receptor alpha	30	0	0	30
estrogen-related nuclear receptor alpha	42	0	0	42
estrogen nuclear receptor alpha	52	0	0	52
peroxisome proliferator activated receptor gamma	25	0	0	25
aryl hydrocarbon receptor	20	0	0	20
chromobox protein homolog 1	17	0	0	17
thyroid hormone receptor beta isoform 2	31	0	0	31
peripheral myelin protein 22	20	0	0	20
cytochrome P450 3A4 isoform 1	13	0	0	13
Gamma-aminobutyric acid receptor subunit pi	13	2	0	15
ATP-binding cassette sub-family C member 3	0	25	0	25
Multidrug resistance-associated protein 4	0	25	0	26
Solute carrier family 22 member 6	0	5	0	5
Carbonic anhydrase 12	0	8	1	15
UDP-glucuronosyltransferase 1A9	0	1	0	2
Bile salt export pump	0	5	0	5
Voltage-dependent calcium channel gamma-2 subunit	23	0	0	23
Bile salt export pump	0	37	0	37
Cytochrome P450 2B1	0	0	0	1
Cytochrome P450 1A1	0	0	0	1
Carbonic anhydrase 1	0	16	1	27
Carbonic anhydrase 2	0	17	2	29
Myoglobin	0	1	0	1
Cytochrome P450 1A1	0	2	1	4
Cytochrome P450 1A2	0	3	1	6
Prostaglandin G/H synthase 1	0	5	0	6
Carbonic anhydrase 3	0	6	1	12
Cytochrome P450 3A4	0	8	1	11
Cytochrome P450 2D6	0	5	1	6
Cytochrome P450 2C9	0	14	1	16
Polyunsaturated fatty acid lipoxygenase ALOX15	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	13	2	0	15
Sulfotransferase 1A1	0	0	0	1
Gamma-aminobutyric acid receptor subunit delta	13	2	0	15
Gamma-aminobutyric acid receptor subunit gamma-2	13	2	0	15
UDP-glucuronosyltransferase 1-6	0	1	0	2
Glutamate receptor 2	24	2	1	27
Gamma-aminobutyric acid receptor subunit alpha-5	13	2	0	15
Gamma-aminobutyric acid receptor subunit alpha-3	13	2	0	15
Arachidonate 5-lipoxygenase-activating protein	0	2	0	2
UDP-glucuronosyltransferase 1A1	0	1	0	2
Carbonic anhydrase 4	0	10	1	16
Prostaglandin G/H synthase 1	0	4	0	4
Carbonic anhydrase 6	0	6	1	12
Gamma-aminobutyric acid receptor subunit gamma-1	13	2	0	15
Gamma-aminobutyric acid receptor subunit alpha-2	13	2	0	15
Gamma-aminobutyric acid receptor subunit alpha-4	13	2	0	15
Gamma-aminobutyric acid receptor subunit gamma-3	13	2	0	15
Gamma-aminobutyric acid receptor subunit alpha-6	13	2	0	15
Carbonic anhydrase 5A, mitochondrial	0	7	1	14
Prostaglandin G/H synthase 2	0	7	1	9
Carbonic anhydrase 7	0	6	1	12
Nuclear receptor ROR-gamma	9	1	1	11
Cytochrome P450 2J2	0	5	0	5
Gamma-aminobutyric acid receptor subunit alpha-1	13	3	0	16
Gamma-aminobutyric acid receptor subunit beta-3	13	2	0	15
Gamma-aminobutyric acid receptor subunit beta-2	13	2	0	15
Carbonic anhydrase 9	0	9	1	16
GABA theta subunit	13	2	0	15
Canalicular multispecific organic anion transporter 1	0	25	0	25
Carbonic anhydrase 15	0	7	0	11
Carbonic anhydrase 13	0	5	0	8
Gamma-aminobutyric acid receptor subunit epsilon	13	2	0	15
Carbonic anhydrase 14	0	6	1	13
Carbonic anhydrase 5B, mitochondrial	0	6	1	13
toxin B	0	0	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	15	0	0	15
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Beta-lactamase	13	0	0	13
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Class Iii Chitinase Chia1	0	1	0	1
Chain A, Carbonic anhydrase 13	0	1	0	1
Chain A, Carbonic anhydrase II	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase	0	1	0	1
Chain B, Carbonic anhydrase	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	3	0	3
thioredoxin reductase	21	0	0	21
GALC protein	6	0	0	6
GLI family zinc finger 3	37	0	0	37
cytochrome P450 family 3 subfamily A polypeptide 4	24	0	0	24
glucocorticoid receptor [Homo sapiens]	38	0	0	38
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	2	0	2
arylsulfatase A	9	0	0	9
Carbonic anhydrase	0	2	0	2
euchromatic histone-lysine N-methyltransferase 2	39	0	0	39
Bloom syndrome protein isoform 1	15	0	0	15
thyroid hormone receptor beta isoform a	13	0	0	13
nuclear factor erythroid 2-related factor 2 isoform 1	30	0	0	30
geminin	31	0	0	31
muscleblind-like protein 1 isoform 1	7	0	0	7
Carbonic anhydrase	0	2	0	2
Prolyl endopeptidase	0	1	0	1
Carbonic anhydrase-related protein 11	0	1	0	2
Glycogen phosphorylase, muscle form	0	1	0	1
Renin	0	2	0	2
Carbonic anhydrase 2	0	2	0	2
Cathepsin B	0	1	0	1
Steryl-sulfatase	0	1	0	1
5-hydroxytryptamine receptor 2C	0	2	0	2
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Cytochrome P450 2C8	0	2	0	2
Cytochrome P450 2A6	0	1	0	1
5-hydroxytryptamine receptor 2A	0	3	0	3
Androgen receptor	0	4	0	4
Translocator protein	0	1	0	1
Cannabinoid receptor 1	0	2	0	2
Cytochrome P450 2B6	0	1	0	1
Carbonic anhydrase 5A, mitochondrial	0	2	0	2
Adenosine receptor A1	0	4	1	7
Serum paraoxonase/arylesterase 1	0	2	0	2
Dipeptidyl peptidase 4	0	1	0	2
Endochitinase	0	1	0	1
Adenosine receptor A2a	0	4	1	7
5-hydroxytryptamine receptor 2B	0	2	0	2
Sodium-dependent serotonin transporter	0	1	0	1
Delta-type opioid receptor	0	3	0	3
Cytochrome P450 2C19	0	4	1	5
Delta-type opioid receptor	0	4	0	4
Mu-type opioid receptor	0	6	0	6
Carbonic anhydrase	0	5	0	8
Kappa-type opioid receptor	0	3	1	4
Carbonic anhydrase	0	1	0	1
D(1A) dopamine receptor	1	1	0	2
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Carbonic anhydrase	0	2	0	6
D(2) dopamine receptor	0	2	0	2
Cholinesterase	0	1	0	1
Carbonic anhydrase	0	2	0	2
Mu-type opioid receptor	0	2	0	2
Fatty-acid amide hydrolase 1	0	3	0	3
Beta-carbonic anhydrase 1	0	3	0	3
Carbonic anhydrase 2	0	2	0	2
Glutamate receptor ionotropic, NMDA 2B	0	4	1	8
Squalene synthase	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase, alpha family	0	2	0	2
Carbonic anhydrase	0	2	0	6
Carbonic anhydrase 3	0	1	0	1
Carbonic anhydrase	0	1	0	6
Carbonic anhydrase	0	2	0	7
Carbonic anhydrase	0	2	0	2
Sigma intracellular receptor 2	0	2	0	2
Delta carbonic anhydrase	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	3	0	3
Renin	0	1	0	1
Carbonic anhydrase	0	2	0	6
Endochitinase A1	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	1
Carbonic anhydrase 13	0	4	1	7
Carbonic anhydrase 4	0	3	0	4
Acidic mammalian chitinase	0	1	0	1
Carbonic anhydrase 7	0	1	0	1
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 2, isoform A	0	1	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	4	0	0	4
Luciferase	13	0	0	13
USP1 protein, partial	21	0	0	21
TDP1 protein	28	0	0	28
AR protein	47	0	0	47
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	24	0	0	24
vitamin D3 receptor isoform VDRA	18	0	0	18
flap endonuclease 1	10	0	0	10
serine/threonine-protein kinase PLK1	5	0	0	5
eyes absent homolog 2 isoform a	3	0	0	3
DNA polymerase eta isoform 1	4	0	0	4
histone acetyltransferase KAT2A isoform 1	14	0	0	14
Rap guanine nucleotide exchange factor 3	7	0	0	7
Cellular tumor antigen p53	32	0	0	32
Rap guanine nucleotide exchange factor 4	4	0	0	4
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain B, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, tRNA (guanine-N(1)-)-methyltransferase	0	0	1	1
Chain A, Uncharacterized protein MJ0883	0	0	1	1
signal transducer and activator of transcription 6, interleukin-4 induced	1	0	0	1
regulator of G-protein signaling 4	12	0	0	12
NPYLR7B	0	0	2	2
IDH1	11	0	0	11
Histone H2A.x	15	0	0	15
glycogen synthase kinase-3 beta isoform 1	0	0	1	1
nuclear receptor ROR-gamma isoform 1	14	0	0	14
high affinity choline transporter 1 isoform a	0	1	0	1
Sodium/nucleoside cotransporter 1	0	2	0	2
Calcium dependent protein kinase	0	1	0	1
Mitogen-activated protein kinase kinase kinase 7	0	0	2	2
Sodium/nucleoside cotransporter 2	0	2	0	2
Purine nucleoside phosphorylase	0	3	0	3
Epidermal growth factor receptor	0	5	0	5
Phosphoglycerate kinase 1	0	1	0	1
Adenosine deaminase	0	0	0	1
Avidin	0	0	1	1
Adenosine deaminase	0	0	0	1
Glyceraldehyde-3-phosphate dehydrogenase	0	2	0	2
Receptor tyrosine-protein kinase erbB-2	0	1	0	1
Insulin receptor	0	0	0	1
Phosphoglycerate kinase 2	0	1	0	1
Heat shock protein HSP 90-alpha	0	1	1	2
Platelet-derived growth factor receptor beta	0	0	0	1
Adenosine receptor A3	0	8	2	11
Heat shock 70 kDa protein 1A	0	1	0	1
Heat shock cognate 71 kDa protein	0	0	1	1
Fibroblast growth factor receptor 1	0	0	0	1
Inosine-5'-monophosphate dehydrogenase 2	0	1	0	1
Endoplasmin	0	1	1	2
Inosine-5'-monophosphate dehydrogenase 1	0	1	0	1
Fibroblast growth factor receptor 2	0	0	0	1
Fibroblast growth factor receptor 4	0	0	0	1
Fibroblast growth factor receptor 3	0	0	0	1
Streptavidin	0	0	1	1
Adenosylhomocysteinase	0	0	0	1
Adenosine receptor A3	0	1	0	1
Adenosine receptor A2a	0	1	2	4
Adenosine receptor A2b	0	1	1	3
Adenosine receptor A2b	0	1	1	2
Adenylate kinase 2, mitochondrial	0	2	0	3
Adenosine receptor A1	0	2	3	6
Adenylate kinase isoenzyme 1	0	2	0	3
Phosphatidylinositol 4-kinase alpha	0	2	0	3
Adenosine receptor A1	0	0	1	1
Adenosine kinase	0	0	0	1
Adenosine deaminase	0	0	0	1
Equilibrative nucleoside transporter 2	0	2	0	2
Phosphatidylinositol 4-kinase type 2-beta	0	2	0	3
Histone-lysine N-methyltransferase, H3 lysine-79 specific	0	1	0	1
Equilibrative nucleoside transporter 1	0	4	0	4
Phosphatidylinositol 4-kinase type 2-alpha	0	2	0	3
Solute carrier family 28 member 3	0	2	0	2
Adenosine kinase	0	1	0	2
Phosphatidylinositol 4-kinase beta	0	2	0	3
5-methylthioadenosine/S-adenosylhomocysteine deaminase	0	0	0	1
Adenosine transporter 1	0	0	0	1
Chain A, Glycogen Phosphorylase B	0	0	1	1
Chain B, Glycogen Phosphorylase B	0	0	1	1
Chain A, ADP-dependent glucokinase	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, phosphodiesterase-nucleotide pyrophosphatase	0	1	0	1
Chain A, GLYCOGEN PHOSPHORYLASE B	0	0	1	1
Chain B, GLYCOGEN PHOSPHORYLASE B	0	0	1	1
Chain A, GLYCOGEN PHOSPHORYLASE B	0	0	1	1
v-jun sarcoma virus 17 oncogene homolog (avian)	14	0	0	14
2'-deoxynucleoside 5'-phosphate N-hydrolase 1	0	1	0	1
2'-deoxynucleoside 5'-phosphate N-hydrolase 1	0	1	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	1	1
Transient receptor potential cation channel subfamily M member 2	0	1	0	1
Alcohol dehydrogenase E chain	0	1	0	1
Alcohol dehydrogenase S chain	0	1	0	1
L-lactate dehydrogenase A chain	0	1	1	2
Adenylate kinase isoenzyme 1	0	0	0	1
Fructose-1,6-bisphosphatase 1	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	3	0	4
Fructose-1,6-bisphosphatase 1	0	1	0	1
2-dehydropantoate 2-reductase	0	1	1	2
Inosine-5'-monophosphate dehydrogenase	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
5'-nucleotidase	0	0	0	1
Choline O-acetyltransferase	0	1	0	1
GTP:AMP phosphotransferase AK3, mitochondrial	0	0	0	1
P2Y purinoceptor 2	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	2	2
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	1	1
Adenylate kinase 2, mitochondrial	0	0	0	1
Glycine--tRNA ligase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	2	2
Adenosine deaminase-like protein	0	0	0	1
Protease	0	3	2	5
P2Y purinoceptor 11	0	0	1	1
Histamine H3 receptor	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	1	1
5'-AMP-activated protein kinase subunit beta-1	0	0	2	2
ATP-dependent phosphofructokinase	12	0	0	12
Chain A, farnesyl pyrophosphate synthase	0	1	0	1
Geranylgeranyl pyrophosphate synthase	0	1	0	1
Farnesyl pyrophosphate synthase	0	4	0	4
Acetylcholinesterase	0	4	1	5
Hypoxanthine-guanine phosphoribosyltransferase	0	1	0	1
Farnesyl pyrophosphate synthase	0	1	0	1
Farnesyl pyrophosphate synthase	0	1	0	1
Chain A, HADH2 protein	11	0	0	11
Chain B, HADH2 protein	11	0	0	11
Chain A, 2-oxoglutarate Oxygenase	12	0	0	12
Chain A, ATP-DEPENDENT DNA HELICASE Q1	6	0	0	6
endonuclease IV	6	0	0	6
15-lipoxygenase, partial	9	0	0	9
WRN	1	0	0	1
estrogen receptor 2 (ER beta)	21	0	0	21
G	16	0	0	16
cytochrome P450 2D6	14	0	0	14
thyroid stimulating hormone receptor	11	0	0	11
polyunsaturated fatty acid lipoxygenase ALOX12	1	0	0	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	9	0	0	9
nuclear factor erythroid 2-related factor 2 isoform 2	13	0	0	15
potassium voltage-gated channel subfamily H member 2 isoform d	12	0	0	12
histone deacetylase 9 isoform 3	3	0	0	3
importin subunit beta-1 isoform 1	7	0	0	7
snurportin-1	7	0	0	7
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	5	0	0	5
tumor susceptibility gene 101 protein	2	0	0	2
DNA polymerase iota isoform a (long)	14	0	0	14
dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	0	1
DNA polymerase kappa isoform 1	9	0	0	9
Vpr	2	0	0	2
kelch-like ECH-associated protein 1	0	0	0	4
Polyunsaturated fatty acid lipoxygenase ALOX15B	6	0	0	6
Interferon beta	22	0	0	22
HLA class I histocompatibility antigen, B alpha chain	16	0	0	16
Transthyretin	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
Apoptosis regulator Bcl-2	0	1	0	1
D(3) dopamine receptor	0	1	0	1
Glutamate receptor 1	1	2	1	4
Glutamate receptor 3	1	2	1	4
Glutamate receptor 4	1	2	1	4
Amine oxidase [flavin-containing] A	0	3	0	3
Amine oxidase [flavin-containing] B	0	2	0	2
Histamine H2 receptor	12	0	1	13
Guanine nucleotide-binding protein G	3	0	0	3
Inositol monophosphatase 1	7	0	0	7
Induced myeloid leukemia cell differentiation protein Mcl-1	0	1	0	1
TAR DNA-binding protein 43	7	0	0	7
Cytochrome P450 1B1	0	2	0	2
RmtA	0	1	0	1
Reverse transcriptase/RNaseH	0	1	0	1
Inositol hexakisphosphate kinase 1	16	0	0	16
Protein arginine N-methyltransferase 1	0	1	0	1
cytochrome P450 2C9, partial	16	0	0	16
phosphoglycerate kinase	1	0	0	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
phosphopantetheinyl transferase	15	0	0	15
NFKB1 protein, partial	5	0	0	5
alpha-galactosidase	3	0	0	3
cytochrome P450 2C19 precursor	9	0	0	9
muscarinic acetylcholine receptor M1	6	0	0	6
lethal factor (plasmid)	6	0	0	6
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, inducible	0	1	0	2
Nitric oxide synthase, inducible	0	0	1	3
Cationic amino acid transporter 3	0	2	0	2
Chain A, Hyaluronidase, phage associated	0	1	0	1
acetylcholinesterase	9	0	0	9
thioredoxin glutathione reductase	13	0	0	13
vitamin D (1,25- dihydroxyvitamin D3) receptor	22	0	0	22
lethal(3)malignant brain tumor-like protein 1 isoform I	2	0	0	2
lamin isoform A-delta10	22	0	0	22
Polyphenol oxidase 2	0	1	0	2
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	1	0	1
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	1	0	1
Alpha-2B adrenergic receptor	0	2	1	3
Spike glycoprotein	15	0	0	15
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
interleukin 8	9	0	0	9
hypothetical protein, conserved	2	0	0	2
glucocerebrosidase	5	0	0	5
peroxisome proliferator-activated receptor delta	22	0	0	22
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
Prostaglandin-H2 D-isomerase	0	2	0	2
Prostaglandin G/H synthase 1	0	2	0	3
Prostaglandin G/H synthase 2	0	2	0	3
Fatty acid-binding protein, liver	0	2	0	2
Integrin beta-3	3	1	1	5
Myeloperoxidase	0	2	0	2
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Integrin alpha-IIb	3	1	1	5
Glutathione hydrolase 1 proenzyme	0	1	0	1
Substance-P receptor	0	3	0	3
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Ras-related protein Rab-2A	0	0	1	1
Prostaglandin G/H synthase 2	0	3	0	3
Rho-associated protein kinase 2	0	2	0	2
Nicotinate phosphoribosyltransferase	0	2	0	2
Solute carrier family 22 member 20	0	2	0	2
Solute carrier family 22 member 6	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	0	1	1
Sigma non-opioid intracellular receptor 1	0	0	1	1
Chain A, Cruzipain	6	0	0	6
SMAD family member 2	13	0	0	13
SMAD family member 3	13	0	0	13
caspase 7, apoptosis-related cysteine protease	6	0	0	6
pregnane X nuclear receptor	26	0	0	26
caspase-3	6	0	0	6
Caspase-7	6	0	0	6
caspase-3	6	0	0	6
Solute carrier organic anion transporter family member 2B1	0	2	0	4
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	2	0	2
ATP-dependent translocase ABCB1	0	6	1	14
Insulin receptor	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Solute carrier organic anion transporter family member 1B3	0	4	0	6
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	4	1	5
Solute carrier organic anion transporter family member 1B1	0	5	0	7
Chain A, Putative fructose-1,6-bisphosphate aldolase	13	0	0	13
calpain II, partial	0	1	0	1
Skn7p	0	0	0	2
hypoxia-inducible factor 1 alpha subunit	13	0	0	13
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	14	0	0	14
envelope glycoprotein	0	1	0	1
nonstructural protein 1	8	0	0	8
farnesoid X nuclear receptor	18	0	0	18
bromodomain adjacent to zinc finger domain 2B	12	0	0	12
photoreceptor-specific nuclear receptor	0	1	0	1
activating transcription factor 6	14	0	0	14
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	11	0	0	11
cytochrome P450 2C9 precursor	8	0	0	8
perilipin-5	0	2	0	2
nuclear receptor corepressor 2 isoform 2	0	1	0	1
perilipin-1	0	2	0	2
heat shock protein beta-1	14	0	0	14
DNA polymerase beta	2	0	0	2
ubiquitin carboxyl-terminal hydrolase 2 isoform a	7	0	0	7
peroxisome proliferator-activated receptor gamma isoform 2	0	1	0	1
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	2	0	2
replicative DNA helicase	0	0	0	1
recombinase A	0	0	1	1
streptokinase A precursor	0	0	2	2
Eyes absent homolog 2	0	3	0	3
Polymerase acidic protein	0	0	1	1
Estrogen receptor	0	0	2	2
60 kDa chaperonin	0	5	0	5
60 kDa heat shock protein, mitochondrial	0	5	0	5
Alpha-1B adrenergic receptor	0	6	0	6
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	1
Mitogen-activated protein kinase 1	0	3	0	3
Multidrug resistance-associated protein 1	0	6	1	9
Alpha-synuclein	2	4	0	6
5-hydroxytryptamine receptor 2B	0	8	0	8
Alpha-1A adrenergic receptor	0	6	0	6
Monocarboxylate transporter 1	0	1	0	1
10 kDa heat shock protein, mitochondrial	0	5	0	5
Disintegrin and metalloproteinase domain-containing protein 17	5	2	0	7
Eyes absent homolog 3	0	1	0	1
Aldo-keto reductase family 1 member C1	0	2	0	2
Mitogen-activated protein kinase 14	0	2	0	2
Thiosulfate sulfurtransferase	0	5	0	5
Solute carrier family 22 member 6	0	4	0	4
60 kDa chaperonin	0	5	0	5
Estrogen receptor beta	0	0	2	2
Monocarboxylate transporter 2	0	1	0	1
10 kDa chaperonin	0	5	0	5
Bile acid receptor	0	0	1	1
Solute carrier family 22 member 12	0	2	0	2
Eyes absent homolog 3	0	1	0	1
Inosine-5'-monophosphate dehydrogenase	0	1	0	1
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	2
M17 leucyl aminopeptidase	0	1	0	1
M1-family alanyl aminopeptidase	0	1	0	1
Chain H, Proteasome component PUP1	0	1	0	1
Chain I, Proteasome component PUP3	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
Proteasome subunit beta type-11	0	1	0	1
Fumarate hydratase	7	0	0	7
PPM1D protein	5	0	0	5
polyprotein	7	0	0	7
nuclear receptor subfamily 1, group I, member 2	5	0	0	5
26S proteasome non-ATPase regulatory subunit 11	0	1	0	1
26S proteasome non-ATPase regulatory subunit 12	0	1	0	1
26S proteasome non-ATPase regulatory subunit 14	0	1	0	1
Proteasome subunit alpha type-7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 3	0	1	0	1
Prothrombin	0	1	1	2
Chymotrypsinogen A	0	1	0	1
Cathepsin B	0	1	0	1
Neutrophil elastase	0	1	0	1
Cathepsin G	0	2	0	2
Lysosomal protective protein	0	2	0	2
Chymotrypsinogen B	0	1	0	1
26S proteasome regulatory subunit 6A	0	1	0	1
Nuclear factor NF-kappa-B p105 subunit	0	1	0	1
Proteasome subunit beta type-1	0	1	0	2
Chymase	0	1	0	1
Proteasome subunit alpha type-1	0	1	0	1
Proteasome subunit alpha type-2	0	1	0	1
Proteasome subunit alpha type-3	0	1	0	1
Proteasome subunit alpha type-4	0	1	0	1
Proteasome subunit beta type-8	0	1	0	1
Proteasome subunit beta type-8	0	1	0	1
Proteasome subunit beta type-9	0	1	0	1
Proteasome subunit alpha type-5	0	1	0	1
Proteasome subunit beta type-4	0	1	0	1
Proteasome subunit beta type-6	0	1	0	1
Proteasome subunit beta type-5	0	2	0	3
26S proteasome regulatory subunit 7	0	1	0	1
Lon protease homolog, mitochondrial	0	1	0	1
Proteasome subunit beta type-10	0	1	0	1
26S proteasome regulatory subunit 6B	0	1	0	1
26S proteasome non-ATPase regulatory subunit 8	0	1	0	1
Proteasome subunit beta type-3	0	1	0	1
Proteasome subunit beta type-2	0	1	0	2
26S proteasome non-ATPase regulatory subunit 7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 4	0	1	0	1
26S proteasome complex subunit SEM1	0	1	0	1
Proteasome subunit alpha type-6	0	1	0	1
26S proteasome regulatory subunit 4	0	1	0	1
26S proteasome regulatory subunit 8	0	1	0	1
26S proteasome regulatory subunit 10B	0	1	0	1
Nuclear factor NF-kappa-B p100 subunit	0	1	0	1
Transcription factor p65	0	1	0	1
26S proteasome non-ATPase regulatory subunit 2	0	1	0	1
26S proteasome non-ATPase regulatory subunit 6	0	1	0	1
Proteasomal ubiquitin receptor ADRM1	0	1	0	1
ATP-dependent Clp protease proteolytic subunit	0	1	1	2
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
Proteasome subunit alpha-type 8	0	1	0	1
ATPase family AAA domain-containing protein 5	16	0	0	16
Proteasome subunit beta type-7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 1	0	1	0	1
Ataxin-2	18	0	0	18
26S proteasome non-ATPase regulatory subunit 13	0	1	0	1
Chain A, CARBONIC ANHYDRASE IV	0	1	0	1
cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 7	0	0	0	1
GTP-binding nuclear protein Ran isoform 1	4	0	0	4
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	0	1	1
Potassium channel subfamily K member 9	0	1	0	1
Chain A, Vitamin D Nuclear Receptor	0	0	1	1
Chain A, Ferritin light chain	10	0	0	10
Vitamin D3 receptor	0	0	1	1
Vitamin D-binding protein	0	0	1	1
Androgen receptor	0	3	1	4
Vitamin D3 receptor	0	2	3	8
Vitamin D3 receptor	0	1	1	3
Retinoic acid receptor RXR-alpha	0	2	3	5
Vitamin D3 receptor	0	0	2	2
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	0	0	1	1
Vitamin D3 receptor	0	1	1	2
Transporter	0	1	0	1
Vitamin D3 receptor A	0	0	2	2
67.9K protein	7	0	0	7
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	3	0	0	3
thyrotropin-releasing hormone receptor	5	0	0	5
Caspase-2	0	0	1	1
Thrombopoietin	3	0	0	3
peripheral myelin protein 22 isoform 1	11	0	0	11
FAD-linked sulfhydryl oxidase ALR	0	0	0	1
urokinase-type plasminogen activator precursor	4	0	0	4
plasminogen precursor	4	0	0	4
urokinase plasminogen activator surface receptor precursor	4	0	0	4
Glycine receptor subunit alpha-1	0	0	1	1
glp-1 receptor, partial	11	0	0	11
LMP1 [Human herpesvirus 4]	0	0	0	2
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	1	0	1
serine/threonine-protein kinase mTOR isoform 1	4	0	0	4
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
nuclear receptor coactivator 3 isoform a	0	1	0	1
Thymidine kinase 2, mitochondrial	0	1	0	1
Thymidine kinase, cytosolic	0	1	0	1
Thymidine kinase	0	1	0	1
Thymidylate synthase	0	2	0	3
Thymidine kinase	0	1	0	1
Deoxycytidine kinase	0	0	0	1
Probable deoxycytidylate deaminase	0	0	0	1
Cytidine deaminase	0	1	0	2
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
Thymidine kinase	0	1	0	1
Deoxynucleoside kinase	0	1	0	1
Deoxycytidine kinase	0	0	0	1
Glutathione S-transferase P	0	1	0	1
Alpha-tocopherol transfer protein	0	0	1	1
apical membrane antigen 1, AMA1	3	0	0	3
Lysine-specific demethylase 6A	0	1	0	1
Lysine-specific demethylase 4A	0	1	0	1
Lysine-specific demethylase 5C	0	1	0	1
Lysine-specific demethylase 2B	0	1	0	1
Deoxyhypusine hydroxylase	0	1	0	1
Lysine-specific demethylase 2A	0	1	0	1
Vascular endothelial growth factor receptor 2	0	1	0	1
Lactoylglutathione lyase	0	2	0	2
Histone acetyltransferase p300	0	1	0	1
CREB-binding protein	0	1	0	1
Ornithine transcarbamylase, mitochondrial	0	1	0	1
Nociceptin receptor	0	1	0	1
Chain A, Breast cancer type 1 susceptibility protein	3	0	0	3
acid sphingomyelinase	3	0	0	3
RGS12	1	0	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
DNA polymerase III, partial	1	0	0	1
isocitrate dehydrogenase 1, partial	1	0	0	1
LANA	0	0	0	1
serine-protein kinase ATM isoform a	2	0	0	2
cytochrome P450 2D6 isoform 1	6	0	0	6
lysosomal alpha-glucosidase preproprotein	4	0	0	4
D(1A) dopamine receptor	1	0	0	1
guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1	1	0	0	1
heat shock protein HSP 90-alpha isoform 2	0	1	0	2
histone-lysine N-methyltransferase 2A isoform 2 precursor	3	0	0	3
caspase-1 isoform alpha precursor	2	0	0	2
DNA dC->dU-editing enzyme APOBEC-3F isoform a	1	0	0	1
neuropeptide S receptor isoform A	2	0	0	2
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	3	0	3
Solute carrier family 22 member 2	0	2	0	3
Solute carrier family 22 member 1	0	5	0	6
Multidrug resistance-associated protein 5	0	1	0	1
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta	0	1	0	1
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	2	0	2
cGMP-specific 3',5'-cyclic phosphodiesterase	0	2	0	2
3',5'-cyclic-AMP phosphodiesterase	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-4	2	1	0	3
Neuronal acetylcholine receptor subunit beta-2	2	1	0	3
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha	0	1	0	1
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	2	0	2
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta	0	1	0	1
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
Caspase-7	2	0	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	2	0	2
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	1	0	1
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	0	1	0	1
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	2	0	2
Exopolyphosphatase PRUNE1	0	1	0	1
Multidrug and toxin extrusion protein 2	0	2	0	2
Multidrug and toxin extrusion protein 1	0	3	0	3
Single-stranded DNA cytosine deaminase	1	0	0	1
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 7B	0	1	0	1
Phosphodiesterase	0	1	0	1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	1	0	1
Amyloid-beta precursor protein	1	3	0	4
Angiotensin-converting enzyme	0	2	0	2
Metallo-beta-lactamase VIM-13	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase VIM-1	0	1	0	1
Endothelin-1 receptor	0	1	0	1
Genome polyprotein	0	1	1	2
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
relaxin receptor 1 isoform 1	2	0	0	2
Flavin reductase (NADPH)	0	0	2	2
large T antigen	0	2	0	2
Type IV secretion-like conjugative transfer relaxase protein TraI	0	1	0	1
Chain A, Uracil Phosphoribosyltransferase	0	1	0	1
pregnane X receptor	6	0	0	6
hemoglobin subunit beta	2	0	0	2
huntingtin isoform 2	2	0	0	2
Solute carrier family 22 member 8	0	1	0	2
Aromatase	0	1	0	1
Chain A, Dihydrofolate reductase	0	0	1	1
Thymidylate synthase	0	2	0	2
Dihydrofolate reductase	0	2	2	5
Aldo-keto reductase family 1 member B1	0	2	0	2
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Solute carrier organic anion transporter family member 1A3	0	2	0	2
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Multidrug resistance associated protein	0	0	0	1
Beta-galactosidase	0	1	0	1
Lipopolysaccharide heptosyltransferase 1	0	1	0	1
PA-I galactophilic lectin	0	0	1	1
Jacalin	0	0	1	1
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
beta-2 adrenergic receptor	2	0	0	2
Metabotropic glutamate receptor 8	0	2	0	2
Metabotropic glutamate receptor 6	0	1	1	3
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Excitatory amino acid transporter 4	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Glutathione reductase, mitochondrial	0	5	0	6
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
ATP-citrate synthase	0	1	0	1
Glutamate receptor ionotropic, kainate 1	0	2	1	3
Metabotropic glutamate receptor 1	0	1	1	2
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 5	0	1	2	3
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Glutamate receptor ionotropic, NMDA 1	0	4	1	8
Glutamate receptor ionotropic, kainate 1	0	1	1	2
Metabotropic glutamate receptor 5	0	1	1	3
Glutamate receptor ionotropic, kainate 2	0	2	1	3
Glutamate receptor 1	0	2	1	3
Glutamate receptor 2	0	2	1	3
Glutamate receptor 3	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	2	0	2
Excitatory amino acid transporter 1	0	2	0	3
Excitatory amino acid transporter 2	0	2	0	3
Excitatory amino acid transporter 3	0	2	0	3
Metabotropic glutamate receptor 8	0	0	1	1
Glutamate receptor 4	0	2	1	3
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Glutamate receptor ionotropic, NMDA 2A	0	3	1	7
Glutamate receptor ionotropic, NMDA 2C	0	3	1	7
Glutamate receptor ionotropic, kainate 4	0	2	0	2
Glutamate carboxypeptidase 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	1	0	1
Glutamate receptor ionotropic, kainate 2	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	1	0	1
Metabotropic glutamate receptor 1	0	1	1	3
Metabotropic glutamate receptor 2	0	1	1	3
Metabotropic glutamate receptor 7	0	1	1	3
Metabotropic glutamate receptor 3	0	1	1	3
Metabotropic glutamate receptor 4	0	1	1	3
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Glutamate receptor ionotropic, kainate 5	0	1	0	1
Carbonic anhydrase-like protein, putative	0	0	0	5
Glutamate receptor ionotropic, NMDA 2D	0	3	1	7
Glutamate receptor ionotropic, kainate 5	0	2	0	2
Glutamate racemase	0	0	0	1
Prolyl 4-hydroxylase	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	3	1	7
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	3	1	7
Chain A, Glutamine Binding Protein	0	0	1	1
Neutral amino acid transporter A	0	3	0	3
Asc-type amino acid transporter 1	0	2	0	2
Neutral amino acid transporter B(0)	0	3	0	3
Amino acid transporter	0	3	0	3
Glutathione reductase	0	0	0	2
Histone-lysine N-methyltransferase EHMT2	0	1	0	1
Histone-lysine N-methyltransferase EHMT1	0	1	0	1
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	1
Ricin	0	1	0	1
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	0	0	1	1
Purine nucleoside phosphorylase	0	0	1	2
Shiga toxin subunit A	0	1	0	1
Guanine deaminase	0	0	0	1
Liver carboxylesterase 1	0	0	0	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Protein (female-specific Histamine Binding Protein 2)	0	0	1	1
aryl hydrocarbon receptor nuclear translocator	0	0	0	1
transforming acidic coiled-coil-containing protein 3	0	0	0	1
Solute carrier family 22 member 3	0	1	0	2
Plasma kallikrein	0	0	0	3
Macrophage migration inhibitory factor	0	2	0	2
Histamine H2 receptor	0	3	2	5
5-hydroxytryptamine receptor 1D	0	0	0	1
Histamine H1 receptor	0	1	3	4
Histamine H1 receptor	0	2	1	3
Histamine H1 receptor	0	2	2	4
Histamine H3 receptor	0	1	0	1
Histamine N-methyltransferase	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	1	0	1
Solute carrier family 22 member 1	0	2	0	3
Equilibrative nucleoside transporter 4	0	0	0	1
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	0	1
Histamine H4 receptor	0	1	2	3
Histamine H3 receptor	0	1	0	1
Carboxylic ester hydrolase	0	0	0	1
Solute carrier family 22 member 2	0	2	0	3
Histamine H3 receptor	0	1	2	3
Glutamine synthetase	0	1	0	1
Proton-coupled amino acid transporter 1	0	2	0	2
Chain A, membrane-associated prostaglandin E synthase-2	0	1	0	1
Parkin	3	0	0	3
ras-related protein Rab-9A	2	0	0	2
M-phase phosphoprotein 8	4	0	0	4
Prostaglandin E synthase	0	1	0	1
Cytochrome c oxidase subunit 2	0	1	0	1
Phospholipase A2, major isoenzyme	0	1	0	1
Albumin	0	1	3	4
Procathepsin L	0	1	0	1
Interleukin-8	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	2
Aldo-keto reductase family 1 member B1	0	2	0	2
Aldo-keto reductase family 1 member C4	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Sodium-dependent dopamine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Thromboxane-A synthase	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	2	0	2
Caspase-1	0	0	0	1
Prostaglandin E2 receptor EP3 subtype	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	0	1
Bifunctional epoxide hydrolase 2	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Prostaglandin E2 receptor EP1 subtype	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	0	1	1
Aldo-keto reductase family 1 member C3	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	1	0	1
C-X-C chemokine receptor type 3	0	1	0	1
Aldo-keto reductase family 1 member C2	0	1	0	1
Prostaglandin D2 receptor	0	2	0	2
Prostaglandin G/H synthase 2	0	1	0	2
Potassium voltage-gated channel subfamily H member 2	0	4	0	4
Uracil nucleotide/cysteinyl leukotriene receptor	0	2	0	2
Solute carrier family 22 member 7	0	1	0	2
Prostaglandin E2 receptor EP2 subtype	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Solute carrier family 22 member 8	0	3	0	3
Dehydrogenase/reductase SDR family member 9	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Cytosolic phospholipase A2 gamma	0	1	0	1
Prostaglandin D2 receptor 2	0	1	1	2
Acetylcholinesterase	0	1	0	1
Acetylcholinesterase	0	0	1	1
Fatty acid synthase	0	1	0	1
Liver carboxylesterase	0	1	0	1
cellular tumor antigen p53 isoform a	3	0	0	3
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	4	0	0	4
Ornithine decarboxylase	0	0	0	2
Retinoic acid receptor alpha	0	2	2	4
Retinoic acid receptor gamma	0	2	2	4
Retinoic acid receptor beta	0	2	2	4
Cellular retinoic acid-binding protein 2	0	0	2	2
Retinoic acid receptor RXR-alpha	0	2	2	4
Retinoic acid receptor RXR-beta	0	2	2	4
Retinoic acid receptor RXR-gamma	0	2	2	4
Cellular retinoic acid-binding protein 1	0	2	0	3
Cellular retinoic acid-binding protein 1	0	0	2	2
Olfactory receptor 51E2	0	1	0	1
Solute carrier organic anion transporter family member 2A1	0	1	0	1
Cysteinyl leukotriene receptor 2	0	0	1	1
Cysteinyl leukotriene receptor 1	0	0	1	1
dopamine D1 receptor	2	0	0	2
atrial natriuretic peptide receptor 1 precursor	2	0	0	2
Alkaline phosphatase, placental type	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	2	0	2
Intestinal-type alkaline phosphatase	0	2	0	2
Intestinal-type alkaline phosphatase	0	1	0	1
5'-nucleotidase	0	1	0	1
Phospholipase A-2-activating protein	0	2	0	2
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, A disintegrin and metalloproteinase with thrombospondin motifs 5	0	1	0	1
Chain A, Catalytic Domain of ADAMTS-5	0	1	0	1
Chain A, A disintegrin and metalloproteinase with thrombospondin motifs 5	0	1	0	1
Zinc metalloproteinase dpy-31	0	1	0	1
Zinc metalloproteinase dpy-31	0	1	0	1
ADAM10	0	1	0	1
disintegrin and metalloproteinase domain-containing protein 17 isoform 1 preproprotein	0	1	0	1
Matrix metalloproteinase-20	0	1	0	1
A disintegrin and metalloproteinase with thrombospondin motifs 4	0	1	0	1
Tumor necrosis factor	0	3	0	3
Interstitial collagenase	0	2	0	3
72 kDa type IV collagenase	0	2	0	3
Stromelysin-1	0	3	0	3
Matrilysin	0	1	0	1
Stromelysin-2	0	1	0	1
Matrix metalloproteinase-9	0	2	0	2
Neutrophil collagenase	0	1	0	1
Macrophage metalloelastase	0	1	0	1
Collagenase 3	0	1	0	2
Matrix metalloproteinase-14	0	1	0	1
Matrix metalloproteinase-15	0	1	0	1
Matrix metalloproteinase-16	0	1	0	1
Matrix metalloproteinase-25	0	1	0	1
Matrix metalloproteinase-26	0	1	0	1
A disintegrin and metalloproteinase with thrombospondin motifs 5	0	1	0	1
Matrix metalloproteinase-24	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	1	0	1
microphthalmia-associated transcription factor isoform 9	0	1	0	1
Neuraminidase	0	1	0	1
Platelet-activating factor receptor	2	0	0	2
Cystathionine gamma-lyase	0	2	0	2
Protein-arginine deiminase type-4	0	2	0	2
Cystine/glutamate transporter	0	1	0	1
Hydroxyacid oxidase 1	0	1	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Glucocorticoid receptor	0	10	2	17
Glycine receptor subunit alpha-1	0	10	0	10
Glycine receptor subunit beta	0	10	0	10
Glycine receptor subunit alpha-2	0	10	0	10
Glycine receptor subunit alpha-3	0	10	0	10
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Chain A, NAD-dependent deacetylase	0	1	0	1
Poly [ADP-ribose] polymerase 2	0	1	0	1
NAD-dependent histone deacetylase SIR2	0	1	0	1
Coagulation factor VII	0	1	0	1
Poly [ADP-ribose] polymerase 1	0	1	0	1
Tissue factor	0	1	0	1
Cytochrome P450 3A5	0	1	0	1
NAD-dependent protein deacetylase HST2	0	1	0	1
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
NAD(+) hydrolase SARM1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-2	0	1	0	1
NAD-dependent protein deacetylase sirtuin-6	0	1	0	1
NAD-dependent protein deacetylase sirtuin-1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	1	0	1
NAD-dependent protein deacetylase	0	1	0	1
Sodium/iodide cotransporter	0	1	0	1
Non-structural protein 1	0	1	0	1
Type II pantothenate kinase	0	0	0	1
Type III pantothenate kinase	0	0	0	1
Succinyl-diaminopimelate desuccinylase	0	1	0	1
vasopressin V1b receptor	1	0	0	1
Cholinesterase	0	1	0	1
Chitotriosidase-1	0	2	1	3
Endochitinase B1	0	2	1	3
Sodium channel protein type 1 subunit alpha	0	2	0	2
Sodium channel protein type 2 subunit alpha	0	2	0	2
Sodium channel protein type 3 subunit alpha	0	2	0	2
Gamma-aminobutyric acid	0	1	0	1
transcriptional regulator ERG isoform 3	1	0	0	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1F	0	2	0	2
Dihydrofolate reductase	0	2	0	2
Sodium channel protein type 2 subunit alpha	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
5-hydroxytryptamine receptor 1A	0	4	0	4
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	1	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1S	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Sodium channel protein type 5 subunit alpha	0	2	0	2
Sodium channel protein type 9 subunit alpha	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
luciferase	0	0	0	1
Estrogen receptor	0	2	0	2
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Corticosteroid-binding globulin	0	1	0	1
Mineralocorticoid receptor	0	2	1	3
Glutamine synthetase	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
Solute carrier organic anion transporter family member 1A4	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Solute carrier organic anion transporter family member 1A1	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	1
Pannexin-1	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	1	0	1
UDP-glucuronosyltransferase 1A7	0	1	0	1
UDP-glucuronosyltransferase 1A10	0	1	0	1
Pannexin-1	0	1	0	1
Solute carrier family 22 member 11	0	2	0	2
Solute carrier family 22 member 8	0	2	0	2
Solute carrier family 22 member 7	0	2	0	2
Glutamate 5-kinase	0	0	0	1
heat shock protein 90, putative	0	0	0	1
dual specificity protein phosphatase 3	0	1	0	1
low molecular weight phosphotyrosine protein phosphatase isoform c	0	1	0	1
tyrosine-protein phosphatase non-receptor type 22 isoform 1	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Solute carrier family 22 member 1	0	1	0	1
Dihydrofolate reductase	0	4	0	4
Beta-hexosaminidase subunit alpha	0	1	0	2
Beta-hexosaminidase subunit beta	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Dihydrofolate reductase	0	3	0	3
Substance-K receptor	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Low molecular weight phosphotyrosine protein phosphatase	0	1	0	1
Pteridine reductase 1	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Trace amine-associated receptor 5	0	0	1	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Multidrug and toxin extrusion protein 1	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Chain A, dATP pyrophosphohydrolase	0	1	0	1
Chain A, Adenylate cyclase type 5	0	1	0	1
Chain B, Adenylate cyclase type 2	0	1	0	1
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR	0	0	1	1
Retinol-binding protein 4	0	0	1	1
Beta-lactoglobulin	0	0	1	1
Kappa-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	0	1	1
exodeoxyribonuclease V subunit RecD	0	1	0	1
exodeoxyribonuclease V subunit RecB	0	1	0	1
exodeoxyribonuclease V subunit RecC	0	1	0	1
ATP-dependent 6-phosphofructokinase	0	1	0	1
Dihydropteroate synthase	0	1	0	1
Endothelin-1 receptor	0	1	0	1
Thymidine phosphorylase	0	1	0	1
Chain A, Nuclear Receptor ROR-beta	0	1	0	1
Ornithine decarboxylase	0	0	0	1
Retinoic acid receptor alpha	0	2	2	7
Retinoic acid receptor beta	0	2	2	7
Retinoic acid receptor gamma	0	2	2	7
Alpha-1A adrenergic receptor	0	1	0	1
Alpha-1D adrenergic receptor	0	1	0	1
Retinoic acid receptor RXR-beta	0	2	2	4
Nuclear receptor ROR-alpha	0	1	0	1
Retinoic acid receptor RXR-gamma	0	2	2	4
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	2	1	3
Indoleamine 2,3-dioxygenase 2	0	1	0	1
Nuclear receptor ROR-beta	0	1	0	1
procathepsin L isoform 1 preproprotein	0	1	0	1
Diamine acetyltransferase 1	0	0	0	1
Thialysine N-epsilon-acetyltransferase	0	0	0	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
Indoleamine 2,3-dioxygenase 1	0	2	0	3
Tryptophan 2,3-dioxygenase	0	1	0	2
Large neutral amino acids transporter small subunit 1	0	2	0	2
SLC16A10 protein	0	0	0	2
Tryprostatin B synthase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Monocarboxylate transporter 10	0	0	0	2
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Tubulin--tyrosine ligase	0	1	0	1
Taste receptor type 2 member 14	0	0	0	1
5-hydroxytryptamine receptor 4	0	2	0	2
Glycoprotein	0	1	0	1
Muscarinic acetylcholine receptor M2	0	0	1	1
ATP-dependent translocase ABCB1	0	1	0	1
Alpha-2A adrenergic receptor	0	2	0	2
ATP-dependent translocase ABCB1	0	1	0	2
Catechol O-methyltransferase	0	1	0	1
Potassium voltage-gated channel subfamily A member 3	0	1	0	1
5-hydroxytryptamine receptor 2A	0	2	0	2
5-hydroxytryptamine receptor 2C	0	2	0	2
5-hydroxytryptamine receptor 1B	0	2	0	2
Sodium-dependent serotonin transporter	0	2	0	2
D(3) dopamine receptor	0	2	0	2
5-hydroxytryptamine receptor 7	0	1	0	1
Chloroquine resistance transporter	0	1	0	1
Aldehyde oxidase 1	0	1	0	1
fructose-bisphosphate aldolase A	1	0	0	1
glyceraldehyde-3-phosphate dehydrogenase isoform 1	1	0	0	1
pyruvate kinase PKM isoform a	1	0	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	0	0	1
Aldehyde oxidase 1	0	1	0	1
Dihydrolipoyl dehydrogenase, mitochondrial	0	0	0	1
Ubiquitin carboxyl-terminal hydrolase isozyme L1	0	1	0	1
Replicase polyprotein 1ab	0	1	0	1
Replicase polyprotein 1ab	0	1	0	1
Pyruvate kinase PKM	0	1	0	1
Ubiquitin carboxyl-terminal hydrolase isozyme L3	0	1	0	1
NAD	0	0	0	2
Protein kinase C alpha type	0	1	0	1
Protein-glutamine gamma-glutamyltransferase 2	0	1	0	1
Dual specificity protein phosphatase 1	0	1	0	1
Trypanothione reductase	0	1	0	3
M-phase inducer phosphatase 1	0	1	0	1
M-phase inducer phosphatase 2	0	1	0	1
M-phase inducer phosphatase 3	0	1	0	1
Tyrosine-protein kinase JAK3	0	1	0	1
Aldehyde oxidase 1	0	1	0	1
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
Aldehyde oxidase	0	1	0	1
Receptor-type tyrosine-protein phosphatase eta	0	1	0	1
Platelet-activating factor acetylhydrolase	0	0	0	1
Receptor protein-tyrosine kinase	0	1	0	1
Aldehyde oxidase 1	0	1	0	1
Dual specificity protein phosphatase 6	0	1	0	1
Ubiquitin carboxyl-terminal hydrolase isozyme L3	0	1	0	1
Ubiquitin carboxyl-terminal hydrolase isozyme L1	0	1	0	1
Aldehyde oxidase 1	0	1	0	1
Albumin	0	0	1	1
Proprotein convertase subtilisin/kexin type 7	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research Excerpts

Overview

Research

Studies (313)

Protein Targets (1,180)

Pseudoxanthoma Elasticum

Synonyms(1)

Research Excerpts

Overview

Research

Studies (313)

Drugs Studied (161)

Protein Targets (1,180)