Page last updated: 2024-09-27

Angiitis, Central Nervous System

Inflammation of blood vessels within the central nervous system. Primary vasculitis is usually caused by autoimmune or idiopathic factors, while secondary vasculitis is caused by existing disease process. Clinical manifestations are highly variable but include HEADACHE; SEIZURES; behavioral alterations; INTRACRANIAL HEMORRHAGES; TRANSIENT ISCHEMIC ATTACK; and BRAIN INFARCTION. (From Adams et al., Principles of Neurology, 6th ed, pp856-61)

Synonyms(14)

Synonym
Secondary CNS Vasculitis
Postzoster Arteritis
Angiitis, Central Nervous System
Cerebral Vasculitis
Central Nervous System Angiitis
CNS Vasculitis
Granulomatous Arteritis
Cerebral Angiitis
Central Nervous System Vasculitis
Primary CNS Vasculitis
Primary Central Nervous System Vasculitis
Granulomatous Angiitis
Vasculitis, CNS, Secondary
Vasculitis, Central Nervous System

Research Excerpts

Overview

ExcerptReference
"Cerebral vasculitis is usually treated with monthly glucocorticoid and cyclophosphamide boluses separated by continuous glucocorticoid therapy."( Ajlani, H; Meddeb, N; Mrabet, D; Sahli, H; Sellami, S, 2007)
"Primary CNS vasculitis is an acutely acquired inflammatory disease with severe neurological deficits and sequelae which may have a fatal outcome."( Herlin, T; Pradsgaard, DØ; Stausbøl-Grøn, B; Østergaard, JR, 2010)
"Cerebral vasculitis is a rare and severe condition, posing problems for diagnosis and treatment."( Allibert, R; Kamdem, FK; Lompo, LD; Medeiros, E; Moulin, T; Revenco, E; Vuillier, F, 2012)
"Cerebral vasculitis is a serious, but uncommon inflammatory condition of the blood vessel walls, with an annual incidence of 1-2 per million."( Borowicz-Klementowicz, J; Cox, A; Klementowicz, P; Martin, P, 2018)
"Primary central nervous system vasculitis is confined to the brain and spinal cord."( Burghaus, L; Deckert, M; Fink, GR; Galldiks, N; Kabbasch, C; Langen, KJ; Ruge, MI, 2018)
"CNS vasculitis is a much rarer complication of drug reactions that may manifest as multifocal ischemia on neuroimaging."( Clark, PA; Gray, JT; Peterson, PG; Roth, M, 2020)

Treatment

ExcerptReference
"The herpes zoster induced cerebral vasculitis was hypothesized as no other etiology could be identified after detailed assessment of the cerebral infarction including brain MRI and cerebrospinal fluid study, and as the clinical course responded to antiviral therapy."( Attout, H; Labouret, P; Rahmeh, F; Ziegler, F, 2000)
"She subsequently developed cerebral vasculitis during treatment with oral cyclophosphamide and prednisolone."( Alton, H; Deshpande, PV; Gilbert, R; Milford, DV, 2000)
"A clinical diagnosis of granulomatous angiitis of the central nervous systems (GANS) was made, and corticosteroid therapy was initiated."( Atsuta, N; Hashizume, Y; Motegi, Y; Sobue, G; Yamada, S, 2003)
"In two patients with progressive CNS vasculitis, the treatment was supplemented by intravenous cyclophosphamide and azathioprin, respectively."( Herlin, T; Pradsgaard, DØ; Stausbøl-Grøn, B; Østergaard, JR, 2010)
"To report the development of CNS vasculitis in a patient with multiple sclerosis (MS) treated with daclizumab."( Bielekova, B; Martin, J; McFarland, H; Oh, U; Ohayon, J; Richert, N; Vortmeyer, A, 2013)
"In cases such as this, allergic cerebral vasculitis should be considered in the differential diagnosis because it can be treated if recognized early, thus leading to remission without the development of any sequelae."( Pirisi, M; Rossi, L; Sainaghi, PP; Sola, D, 2013)
"The majority of patients with primary CNS vasculitis responded to treatment."( Brown, RD; Christianson, TJ; Giannini, C; Hunder, GG; Huston, J; Miller, DV; Salvarani, C, 2015)
"In all children, no relapse of cerebral vasculitis occurred during the whole follow-up period and all of them improved while in MMF treatment."( Basile, M; Brambilla, A; Cimaz, R; Cosi, A; Guerrini, R; Rosati, A; Simonini, G, 2017)
"A retrospective diagnosis of BCG-induced central nervous system vasculitis was made and he was treated with high-dose corticosteroids, moxifloxacin, isoniazid, ethambutol, and rifampicin."( Liang, P; Parent, ME; Richer, M, 2018)
"Here, we report a case of central nervous system vasculitis in rheumatoid arthritis (RA) treated successfully with corticosteroid and mycophenolate."( Das, S; Ghosal, A; Purkayastha, S; Sinha, D, 2023)

Research

Studies (263)

TimeframeStudies, This Condition (%)All Conditions %
pre-19901 (0.38)23.3326
1990's1 (0.38)12.5806
2000's110 (41.83)18.1394
2010's113 (42.97)28.8240
2020's38 (14.45)9.53
DrugIndicatedRelationship StrengthStudiesTrials
ammonium hydroxide0low10
choline0low20
salicylic acid0low10
n(g),n(g')-dimethyl-l-arginine0low10
cytosine0low10
nickel0low10
nitrates0low10
oxyquinoline0low10
tyrphostin ag 10240low10
albendazole0low10
albuterol0low10
aspirin0low60
azathioprine0low120
chlorpromazine0low10
dapsone0low10
amphetamine0low30
valproic acid0low20
doxepin0low10
ebselen0low10
etidronate0low10
furosemide0low10
glimepiride0low10
indomethacin0low10
iofetamine0low10
ketoconazole0low10
leflunomide0low10
edaravone0low10
mesalamine0low20
methylphenidate0low10
modafinil0low10
nimodipine0low20
pentoxifylline0low10
praziquantel0low10
thalidomide0low20
ticlopidine0low10
prednisolone0low410
thyroxine0low10
spironolactone0low10
aldosterone0low10
prednisone0low290
methylprednisolone acetate0low10
penicillin g0low30
glutamine0low10
tyrosine0low10
cysteamine0low10
colchicine0low10
cytarabine0low10
medroxyprogesterone acetate0low10
valine0low10
arginine0low10
methylprednisolone0medium421
trolnitrate0low10
deoxycytidine0low10
vancomycin0low10
fluorescein0low10
methylprednisolone hemisuccinate0low10
gadolinium0low80
xenon0low10
trolamine salicylate0low20
phenyl acetate0low10
glutamic acid0low10
amoxicillin0low10
diltiazem0low10
propiconazole0low10
clopidogrel0low10
cidofovir anhydrous0low10
gemcitabine0low10
atorvastatin0low10
lamivudine0low10
fluorodeoxyglucose f180low30
fibrinogen0low10
homocysteine0low10
imatinib mesylate0low10
n,n-dimethylarginine0low10
methotrexate0low50
moxifloxacin0low10
organophosphonates0low10
deflazacort0low10
trimethoprim, sulfamethoxazole drug combination0low10
eplerenone0low10
tacrolimus0low20
cocaine0low30
mycophenolic acid0low170
stilbenes0low10
propylthiouracil0low10
methimazole0low10
telaprevir0low10
indium oxine0low10
cystine0low10
dinoprostone0low10
leukotriene b40low10
montelukast0low10
lisinopril0low10
cefotaxime0low10
mocetinostat0low70
indocyanine green0low20
ro13-99040low30
o-(2-fluoroethyl)tyrosine0low10
minocycline0low10
insulin glargine0low10
cyclosporine0low10
acyclovir0low110
ganciclovir0low10
valacyclovir0low10
olanzapine0low10
allopurinol0low20
valganciclovir0low10
cholestyramine resin0low10
eye0low10

Protein Targets (1,198)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, TYROSYL-DNA PHOSPHODIESTERASE110011
5-hydroxytryptamine receptor 3E0202
acetylcholinesterase120012
TDP1 protein390039
cytochrome P450 2D6140014
v-jun sarcoma virus 17 oncogene homolog (avian)170017
cytochrome P450 2D6 isoform 16006
cellular tumor antigen p53 isoform a9009
cytochrome P450 2C19 precursor9009
cytochrome P450 2C9 precursor8008
thyroid hormone receptor beta isoform a130013
thyroid hormone receptor beta isoform 2310031
huntingtin isoform 24004
peripheral myelin protein 22170017
cytochrome P450 3A4 isoform 1160016
muscarinic acetylcholine receptor M1100010
Gamma-aminobutyric acid receptor subunit pi160016
Polyunsaturated fatty acid lipoxygenase ALOX15B6006
ATP-binding cassette sub-family C member 3036036
Multidrug resistance-associated protein 4036038
5-hydroxytryptamine receptor 3B0202
Bile salt export pump048048
Beta-1 adrenergic receptor0123
5-hydroxytryptamine receptor 1A0325
5-hydroxytryptamine receptor 2C09111
D(2) dopamine receptor0809
5-hydroxytryptamine receptor 2A010111
Gamma-aminobutyric acid receptor subunit beta-1160016
Alpha-1B adrenergic receptor0707
Gamma-aminobutyric acid receptor subunit delta160016
Gamma-aminobutyric acid receptor subunit gamma-2160016
D0505
5-hydroxytryptamine receptor 1A010111
Gamma-aminobutyric acid receptor subunit alpha-5160016
Gamma-aminobutyric acid receptor subunit alpha-3160016
Gamma-aminobutyric acid receptor subunit gamma-1160016
Gamma-aminobutyric acid receptor subunit alpha-2160016
Alpha-1D adrenergic receptor0505
5-hydroxytryptamine receptor 2A09110
5-hydroxytryptamine receptor 2C09110
Gamma-aminobutyric acid receptor subunit alpha-4160016
Gamma-aminobutyric acid receptor subunit gamma-3160016
5-hydroxytryptamine receptor 1B010111
5-hydroxytryptamine receptor 1D0415
Gamma-aminobutyric acid receptor subunit alpha-6160016
5-hydroxytryptamine receptor 1F0415
5-hydroxytryptamine receptor 5A0101
5-hydroxytryptamine receptor 2B0819
Sodium-dependent serotonin transporter018119
5-hydroxytryptamine receptor 7 0415
5-hydroxytryptamine receptor 70303
Alpha-1B adrenergic receptor0202
Glutamate receptor ionotropic, NMDA 1 1518
5-hydroxytryptamine receptor 2B011112
Alpha-1A adrenergic receptor0808
5-hydroxytryptamine receptor 3A0202
Histamine H2 receptor121014
5-hydroxytryptamine receptor 6010010
Beta-2 adrenergic receptor0101
D(2) dopamine receptor0607
Gamma-aminobutyric acid receptor subunit alpha-1161017
Gamma-aminobutyric acid receptor subunit beta-3160016
Gamma-aminobutyric acid receptor subunit beta-2160016
Glutamate receptor ionotropic, NMDA 2A 1518
Glutamate receptor ionotropic, NMDA 2B1518
Glutamate receptor ionotropic, NMDA 2C1518
Glutamate receptor ionotropic, NMDA 2D1518
5-hydroxytryptamine receptor 3D0202
Glutamate receptor ionotropic, NMDA 3B1518
5-hydroxytryptamine receptor 3C0202
GABA theta subunit160016
Canalicular multispecific organic anion transporter 1035035
Gamma-aminobutyric acid receptor subunit epsilon160016
Glutamate receptor ionotropic, NMDA 3A1518
Chain E, Purine nucleoside phosphorylase0101
Chain A, HADH2 protein8008
Chain B, HADH2 protein8008
Chain A, ATP-DEPENDENT DNA HELICASE Q14004
Chain A, Ferritin light chain100010
Thymidine kinase 0303
thioredoxin reductase250025
phosphopantetheinyl transferase140014
GLS protein160016
Smad37007
thyroid stimulating hormone receptor150015
EWS/FLI fusion protein200020
arylsulfatase A130013
euchromatic histone-lysine N-methyltransferase 2380038
activating transcription factor 69009
Histone H2A.x120012
Bloom syndrome protein isoform 1120012
hemoglobin subunit beta2002
atrial natriuretic peptide receptor 1 precursor3003
ubiquitin carboxyl-terminal hydrolase 2 isoform a4004
lamin isoform A-delta10280028
Solute carrier family 22 member 1 0408
Solute carrier family 22 member 60608
Bile salt export pump016016
Purine nucleoside phosphorylase0101
Thymidine kinase, cytosolic0102
POU domain, class 2, transcription factor 20002
Cytochrome P450 2C9 011011
Cytochrome P450 2J20909
Disintegrin and metalloproteinase domain-containing protein 174004
Purine nucleoside phosphorylase0033
Solute carrier family 22 member 60409
Thymidine kinase 0101
Solute carrier family 22 member 80408
Thymidine kinase0202
Chain A, Beta-lactamase8008
Luciferase140014
glp-1 receptor, partial120012
hypoxia-inducible factor 1 alpha subunit100010
RAR-related orphan receptor gamma240024
ATAD5 protein, partial120012
Fumarate hydratase8008
GLI family zinc finger 3220022
AR protein420042
caspase 7, apoptosis-related cysteine protease6006
nuclear receptor subfamily 1, group I, member 3240024
progesterone receptor210021
glucocorticoid receptor [Homo sapiens]340034
retinoic acid nuclear receptor alpha variant 1260026
retinoid X nuclear receptor alpha280028
estrogen-related nuclear receptor alpha320032
farnesoid X nuclear receptor220022
pregnane X nuclear receptor270027
estrogen nuclear receptor alpha530053
polyprotein8008
67.9K protein9009
peroxisome proliferator activated receptor gamma220022
vitamin D (1,25- dihydroxyvitamin D3) receptor210021
caspase-36006
IDH1170017
aryl hydrocarbon receptor230023
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a220022
nuclear receptor subfamily 1, group I, member 29009
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 18008
chromobox protein homolog 1140014
nuclear factor erythroid 2-related factor 2 isoform 2130013
transcriptional regulator ERG isoform 34004
histone deacetylase 9 isoform 34004
heat shock protein beta-19009
mitogen-activated protein kinase 16006
urokinase-type plasminogen activator precursor7007
plasminogen precursor7007
urokinase plasminogen activator surface receptor precursor7007
geminin320032
Vif0001
survival motor neuron protein isoform d130013
muscleblind-like protein 1 isoform 17007
DNA dC->dU-editing enzyme APOBEC-3G isoform 12002
neuropeptide S receptor isoform A8008
Voltage-dependent calcium channel gamma-2 subunit180018
Interferon beta220022
Cellular tumor antigen p53250025
Integrin beta-34116
Integrin alpha-IIb4116
Methionine aminopeptidase0101
Glutamate receptor 2183122
Fatty-acid amide hydrolase 10202
Inositol monophosphatase 13003
ATPase family AAA domain-containing protein 5150015
Ataxin-2180018
regulator of G-protein signaling 4100010
NPYLR7B0011
thyroid stimulating hormone receptor9009
flap endonuclease 1100010
Beta-2 adrenergic receptor0426
60 kDa chaperonin0202
60 kDa heat shock protein, mitochondrial0404
Beta-3 adrenergic receptor0213
Delta-type opioid receptor0112
10 kDa heat shock protein, mitochondrial0404
Thiosulfate sulfurtransferase0404
Beta-2 adrenergic receptor 0013
60 kDa chaperonin 0404
10 kDa chaperonin 0404
Beta-2 adrenergic receptor0224
ATP-dependent phosphofructokinase110011
Sex hormone-binding globulin0022
Corticosteroid-binding globulin0202
Mineralocorticoid receptor 08413
Androgen receptor0809
Mineralocorticoid receptor0303
Solute carrier organic anion transporter family member 1A10102
Guanine nucleotide-binding protein G6006
interleukin 8110011
estrogen receptor 2 (ER beta)170017
ras-related protein Rab-9A5005
nuclear factor erythroid 2-related factor 2 isoform 1300030
Polyphenol oxidase 20407
Hypoxanthine-guanine phosphoribosyltransferase0001
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase 0101
Adenosine receptor A2a0011
Xanthine dehydrogenase/oxidase0202
Nuclear receptor ROR-gamma0101
Xanthine dehydrogenase/oxidase0315
TAR DNA-binding protein 436006
Shiga toxin subunit A0101
Histamine H3 receptor0103
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE260026
Chain A, 2-oxoglutarate Oxygenase9009
Beta-lactamase 0002
Beta-lactamase 0003
Beta-lactamase 0003
Beta-lactamase 0003
apical membrane antigen 1, AMA13003
Beta-lactamase 0003
peptidyl-prolyl cis-trans isomerase NIMA-interacting 17007
DNA polymerase eta isoform 13003
DNA polymerase iota isoform a (long)190019
DNA polymerase kappa isoform 1100010
Beta-lactamase SHV-10003
Beta-lactamase SHV-10003
Beta-lactamase0003
Kappa-type opioid receptor0003
Solute carrier family 15 member 10506
Solute carrier family 15 member 10202
B2 metallo-beta-lactamase 0003
Solute carrier family 15 member 20303
Beta-lactamase 0003
Beta-lactamase 0003
Solute carrier family 15 member 20404
Beta-lactamase 0003
Beta-lactamase 0003
Solute carrier family 22 member 30101
Phenylethanolamine N-methyltransferase0202
Cytochrome P450 2A60202
Substance-P receptor0101
Cytochrome P450 2A50101
Sodium-dependent dopamine transporter09110
5-hydroxytryptamine receptor 60213
5-hydroxytryptamine receptor 5A0213
5-hydroxytryptamine receptor 5B0213
5-hydroxytryptamine receptor 3A0213
Sigma non-opioid intracellular receptor 10404
5-hydroxytryptamine receptor 4 0213
5-hydroxytryptamine receptor 3B0213
Sigma non-opioid intracellular receptor 10112
Chain A, Cruzipain8008
peroxisome proliferator-activated receptor delta220022
tumor necrosis factor1001
vitamin D3 receptor isoform VDRA160016
Cytochrome P450 1A20314
Cytochrome P450 3A4013118
Cytochrome P450 2D60618
Cytochrome P450 2C190909
Nuclear receptor ROR-gamma100010
Potassium voltage-gated channel subfamily H member 2012013
Aurora kinase B0101
Broad substrate specificity ATP-binding cassette transporter ABCG20708
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
NFKB1 protein, partial6006
alpha-galactosidase4004
lethal factor (plasmid)8008
Nitric oxide synthase, endothelial0002
Nitric oxide synthase, brain0102
Nitric oxide synthase, brain 0102
Nitric oxide synthase, inducible0102
Nitric oxide synthase, inducible0013
Cationic amino acid transporter 30101
Chain A, Phospholipase A2 isoform 30011
GTP-binding protein (rab7)0011
ras protein, partial0011
aldehyde dehydrogenase 1 family, member A1180018
hypothetical protein, conserved2002
cytochrome P450 family 3 subfamily A polypeptide 4250025
glucocerebrosidase7007
Rac1 protein0011
cell division cycle 42 (GTP binding protein, 25kDa), partial0011
Prostaglandin-H2 D-isomerase0202
Prostaglandin G/H synthase 1 0405
Prostaglandin G/H synthase 2 0304
Epidermal growth factor receptor0404
Carbonic anhydrase 106010
Carbonic anhydrase 206111
Fatty acid-binding protein, liver0202
Myeloperoxidase0303
Prostaglandin G/H synthase 10506
Seed linoleate 13S-lipoxygenase-10101
Glutathione hydrolase 1 proenzyme0101
Prostaglandin G/H synthase 10404
Adenosine receptor A10304
Adenosine receptor A2a0304
Substance-P receptor0202
Prostaglandin G/H synthase 20819
Urotensin-2 receptor0101
4-aminobutyrate aminotransferase, mitochondrial0101
Ras-related protein Rab-2A0011
Prostaglandin G/H synthase 20404
Rho-associated protein kinase 20202
Nicotinate phosphoribosyltransferase0303
Solute carrier family 22 member 200404
Solute carrier family 22 member 60404
Sigma non-opioid intracellular receptor 118110
SMAD family member 2130013
SMAD family member 3130013
Caspase-73003
caspase-33003
Solute carrier organic anion transporter family member 2B1 0406
3-hydroxy-3-methylglutaryl-coenzyme A reductase0202
ATP-dependent translocase ABCB108011
Insulin receptor 0101
Dipeptidyl peptidase 40101
3-hydroxy-3-methylglutaryl-coenzyme A reductase 0202
Histone deacetylase 10505
Histone deacetylase 20505
Solute carrier organic anion transporter family member 1B30408
Histone deacetylase 60505
Solute carrier organic anion transporter family member 1B106010
Atrial natriuretic peptide receptor 10011
Atrial natriuretic peptide receptor 1 0011
Microtubule-associated protein tau9009
thioredoxin glutathione reductase5005
G150015
P532002
peripheral myelin protein 22 isoform 17007
M-phase phosphoprotein 87007
HLA class I histocompatibility antigen, B alpha chain 150015
Inositol hexakisphosphate kinase 1150015
Protein-arginine deiminase type-40606
cytochrome P450 2C9, partial150015
Beta-lactamase 0002
Beta-lactamase 0002
Beta-lactamase 0102
Beta-lactamase 0002
Metallo-beta-lactamase type 20002
Metallo-beta-lactamase VIM-11 0002
Metallo-beta-lactamase VIM-20002
Beta-lactamase 0002
Metallo-beta-lactamase VIM-19 0002
Beta-lactamase 0002
Beta-lactamase 0002
Metallo-beta-lactamase0002
Beta-lactamase 0102
Albumin03710
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-beta-lactamase VIM-130002
Beta-lactamase 0002
Beta-lactamase 0002
Metallo-beta-lactamase VIM-20002
Beta-lactamase 0001
Beta-lactamase Toho-10002
Solute carrier family 22 member 70104
Metallo-beta-lactamase0001
Beta-lactamase 0001
Metallo-b-lactamase 0002
BlaVIM-1 0002
Beta-lactamase 0002
Beta-lactamase 0002
Carbapenem-hydrolyzing beta-lactamase KPC0002
Beta-lactamase class B VIM-2 0002
Solute carrier family 22 member 110103
Solute carrier family 22 member 80203
Beta-lactamase VIM-1 0002
Solute carrier family 22 member 70102
Proteasome subunit beta type-110001
USP1 protein, partial120012
Thrombopoietin4004
NADPH oxidase 10101
Snq2p0001
Adenylate cyclase type 1 0202
Spike glycoprotein0235
Replicase polyprotein 1ab0235
D(1A) dopamine receptor4004
potassium voltage-gated channel subfamily H member 2 isoform d6006
atrial natriuretic peptide receptor 2 precursor3003
serine/threonine-protein kinase mTOR isoform 15005
histone acetyltransferase KAT2A isoform 1120012
Proteasome subunit alpha type-70001
Transmembrane protease serine 20235
Glutamate receptor ionotropic, NMDA 2D0202
Transient receptor potential cation channel subfamily V member 10101
Glutamate receptor ionotropic, NMDA 3B0202
Voltage-dependent L-type calcium channel subunit alpha-1F0505
5-hydroxytryptamine receptor 40808
Potassium channel subfamily K member 20101
Albumin0011
Major prion protein0011
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10101
Receptor tyrosine-protein kinase erbB-20101
Major prion protein0011
Tyrosine-protein kinase Fyn0202
Procathepsin L0437
Aldo-keto reductase family 1 member B1011011
Muscarinic acetylcholine receptor M20707
Muscarinic acetylcholine receptor M40606
Muscarinic acetylcholine receptor M10202
Muscarinic acetylcholine receptor M30101
Muscarinic acetylcholine receptor M40101
Muscarinic acetylcholine receptor M50101
Muscarinic acetylcholine receptor M50606
Alpha-2A adrenergic receptor015015
Replicase polyprotein 1a0235
Replicase polyprotein 1ab0235
Replicase polyprotein 1ab0437
Cys-loop ligand-gated ion channel0101
Calmodulin-10213
Replicase polyprotein 1ab0437
Muscarinic acetylcholine receptor M20101
Muscarinic acetylcholine receptor M10718
Polyunsaturated fatty acid lipoxygenase ALOX150404
Angiotensin-converting enzyme0505
Sphingomyelin phosphodiesterase0101
Alpha-2B adrenergic receptor012012
Alpha-2C adrenergic receptor010010
D(3) dopamine receptor0303
Alpha-2B adrenergic receptor0505
D(2) dopamine receptor0101
Muscarinic acetylcholine receptor M30808
Proteasome subunit beta type-10001
Substance-K receptor0606
D(1A) dopamine receptor0809
D(4) dopamine receptor0506
D(1B) dopamine receptor0102
Adenylate cyclase type 30202
Alpha-2C adrenergic receptor0505
UDP-glucuronosyltransferase 1A40003
Alpha-2A adrenergic receptor0505
Sodium-dependent noradrenaline transporter 018119
Histamine H2 receptor0808
Alpha-1D adrenergic receptor0606
D(1B) dopamine receptor0202
Proteasome subunit alpha type-10001
Proteasome subunit alpha type-20001
Proteasome subunit alpha type-30001
Proteasome subunit alpha type-40001
Adenylate cyclase type 20202
Adenylate cyclase type 40202
Proteasome subunit beta type-80001
Proteasome subunit beta type-90001
Proteasome subunit alpha type-50001
Proteasome subunit beta type-40001
Proteasome subunit beta type-60001
Proteasome subunit beta type-50001
Trypanothione reductase0202
D(4) dopamine receptor0303
Histamine H1 receptor0214
Melanocortin receptor 40202
Melanocortin receptor 50202
Pleiotropic ABC efflux transporter of multiple drugs0102
Histamine H1 receptor0617
Mu-type opioid receptor0202
D(3) dopamine receptor011012
Sodium channel protein type 1 subunit alpha0202
Sodium channel protein type 4 subunit alpha0202
Adenylate cyclase type 80202
Proteasome subunit beta type-100001
Delta-type opioid receptor0606
Kappa-type opioid receptor0202
Melanocortin receptor 30202
Proteasome subunit beta type-30001
Proteasome subunit beta type-20001
D(1A) dopamine receptor2002
5-hydroxytryptamine receptor 70202
Gastrin/cholecystokinin type B receptor0101
Spike glycoprotein162321
Proteasome subunit alpha type-60012
Calmodulin 0112
Aldehyde oxidase 10101
Sodium channel protein type 7 subunit alpha0202
Voltage-dependent L-type calcium channel subunit alpha-1D 0505
Sodium-dependent dopamine transporter 016117
Adenylate cyclase type 60202
Adenylate cyclase type 50202
Glutamate receptor ionotropic, NMDA 10202
Aldehyde oxidase0202
Glutamate receptor ionotropic, NMDA 2A0202
Glutamate receptor ionotropic, NMDA 2B0202
Voltage-dependent L-type calcium channel subunit alpha-1S0505
Voltage-dependent L-type calcium channel subunit alpha-1C0505
Sodium channel protein type 5 subunit alpha0303
Glutamate receptor ionotropic, NMDA 2C0202
Sodium channel protein type 9 subunit alpha0202
Nuclear receptor subfamily 3 group C member 3 0303
Adenylyl cyclase 7 0202
Proteasome subunit alpha-type 80001
Glutamate receptor ionotropic, NMDA 3A0202
D0101
Sodium channel protein type 2 subunit alpha0202
Proteasome subunit beta type-70001
Angiotensin-converting enzyme 2 0235
Sodium channel protein type 3 subunit alpha0202
Sodium channel protein type 11 subunit alpha0202
Sodium channel protein type 8 subunit alpha0202
Histamine H3 receptor0101
Sodium channel protein type 10 subunit alpha0202
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein0011
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Choline-binding protein0011
Solute carrier family 22 member 10102
Solute carrier family 22 member 20002
Solute carrier family 22 member 20101
Neuronal acetylcholine receptor subunit alpha-30101
Neuronal acetylcholine receptor subunit alpha-40202
Neuronal acetylcholine receptor subunit alpha-20101
Neuronal acetylcholine receptor subunit beta-20202
Neuronal acetylcholine receptor subunit beta-30101
Neuronal acetylcholine receptor subunit beta-40101
Neuronal acetylcholine receptor subunit alpha-50101
Acetylcholinesterase0505
Sodium- and chloride-dependent creatine transporter 10101
Choline O-acetyltransferase 0001
Neuronal acetylcholine receptor subunit alpha-60101
Neuronal acetylcholine receptor subunit alpha-90101
Neuronal acetylcholine receptor subunit alpha-70101
Solute carrier family 22 member 10102
High affinity choline transporter 10101
Neuronal acetylcholine receptor subunit alpha-100101
Solute carrier family 22 member 20102
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase0011
Thymidine kinase0001
nonstructural protein 18008
parathyroid hormone/parathyroid hormone-related peptide receptor precursor4004
Cytochrome P450 2C80405
Cytochrome P450 2B60314
Liver carboxylesterase 10103
Rap guanine nucleotide exchange factor 42002
P2Y purinoceptor 120101
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain H, Fab M82G2, Heavy chain0011
Chain L, Fab M82G2, Light chain0011
Chain H, Fab M82g2, Heavy Chain0011
Chain L, Fab M82g2, Light Chain0011
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit delta0101
Amyloid-beta precursor protein1203
Fatty acid-binding protein, heart0101
Muscarinic acetylcholine receptor M20101
Tryptophan 5-hydroxylase 10101
Gamma-aminobutyric acid receptor subunit alpha-10101
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit gamma-20101
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0303
Gamma-aminobutyric acid receptor subunit beta-30101
Gamma-aminobutyric acid receptor subunit alpha-50101
Sodium-dependent serotonin transporter09111
Gamma-aminobutyric acid receptor subunit alpha-30101
Lysosomal Pro-X carboxypeptidase0101
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit beta-20101
Gamma-aminobutyric acid receptor subunit alpha-40101
Gamma-aminobutyric acid receptor subunit epsilon0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0303
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0404
Leukotriene B4 receptor 10303
Gamma-aminobutyric acid receptor subunit alpha-60101
Sodium-dependent dopamine transporter0202
Gamma-aminobutyric acid receptor subunit gamma-10101
Gamma-aminobutyric acid receptor subunit gamma-30101
Leukotriene B4 receptor 20202
Gamma-aminobutyric acid receptor subunit theta0101
Transporter0606
endonuclease IV6006
PAX80001
pregnane X receptor6006
PPM1D protein7007
nuclear receptor subfamily 0 group B member 10101
steroidogenic factor 10101
caspase-1 isoform alpha precursor3003
Solute carrier family 22 member 30101
Tubulin alpha-1A chain0213
Tubulin beta chain0213
Plasma kallikrein0002
Tubulin beta-4A chain0225
ATP-dependent translocase ABCB10303
Tubulin beta chain0225
Tubulin alpha-3C chain0225
Serine/threonine-protein kinase pim-10101
ATP-dependent translocase ABCB10303
Tubulin alpha-1B chain0225
Tubulin alpha-4A chain0225
Tubulin beta-4B chain0225
Vesicular acetylcholine transporter0101
Tubulin beta-3 chain0225
Tubulin beta-2A chain0225
Tubulin polymerization-promoting protein0011
Tubulin beta-8 chain0225
Tubulin beta-2B chain0202
Tubulin alpha-3E chain0225
Tubulin alpha-1A chain0225
Similar to alpha-tubulin isoform 1 0101
Similar to alpha-tubulin isoform 1 0101
CREB-binding protein1001
Tubulin alpha-1C chain0225
Tubulin beta-6 chain0225
Tubulin beta-2B chain0225
Tubulin beta-1 chain0225
Histone-lysine N-methyltransferase EHMT20202
Glutaminyl-peptide cyclotransferase0101
Histone-lysine N-methyltransferase EHMT10202
LMP1 [Human herpesvirus 4]0002
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0202
transactivating tegument protein VP16 [Human herpesvirus 1]0202
nuclear receptor coactivator 3 isoform a0202
Thymidine kinase 2, mitochondrial0101
Thymidine kinase0101
Thymidylate synthase0203
Thymidine kinase0101
Deoxycytidine kinase0003
Probable deoxycytidylate deaminase0002
Cytidine deaminase0104
E3 ubiquitin-protein ligase Mdm20101
Enoyl-[acyl-carrier-protein] reductase [NADH] 0101
Deoxynucleoside kinase0101
Deoxycytidine kinase0001
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase 0101
bromodomain adjacent to zinc finger domain 2B6006
Dihydrofolate reductase0303
Thymidine kinase 2 0101
AAA family ATPase 0002
Reverse transcriptase/RNaseH 0022
Voltage-dependent L-type calcium channel subunit alpha-1C0303
Voltage-dependent L-type calcium channel subunit alpha-1C0404
Voltage-dependent L-type calcium channel subunit alpha-1D0303
Voltage-dependent L-type calcium channel subunit alpha-1S0303
Potassium voltage-gated channel subfamily A member 10101
prostaglandin E2 receptor EP2 subtype1001
Solute carrier organic anion transporter family member 1A50002
Prostaglandin E2 receptor EP3 subtype0202
Prostaglandin E2 receptor EP4 subtype0202
Prostaglandin E2 receptor EP1 subtype0213
Prostaglandin E2 receptor EP1 subtype0202
Prostaglandin E2 receptor EP4 subtype0213
Prostaglandin F2-alpha receptor0011
Prostaglandin E2 receptor EP4 subtype0112
Prostaglandin E2 receptor EP3 subtype0213
Prostaglandin E2 receptor EP2 subtype0213
Prostacyclin receptor0213
Solute carrier organic anion transporter family member 2A10102
Prostaglandin E2 receptor EP2 subtype0202
Prostaglandin E2 receptor EP2 subtype0112
Solute carrier family 22 member 70001
Solute carrier organic anion transporter family member 2A10001
Solute carrier organic anion transporter family member 1B20001
Histamine H1 receptor0101
Chain A, Putative fructose-1,6-bisphosphate aldolase6006
Chain A, JmjC domain-containing histone demethylation protein 3A5005
RNA polymerase beta subunit (EC 2.7.7.6), partial0101
Nrf21001
RGS121001
15-lipoxygenase, partial5005
Arrestin, beta 10101
MPI protein0101
DNA polymerase III, partial2002
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)7007
isocitrate dehydrogenase 1, partial1001
luciferase1001
pyruvate kinase2002
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase0101
TPA: protein transporter TIM100101
TPA: protein transporter TIM230101
hexokinase0101
hexokinase-4 isoform 12002
hexokinase-1 isoform HKI0011
neutrophil cytosol factor 10101
phosphomannomutase 20101
polyunsaturated fatty acid lipoxygenase ALOX122002
perilipin-50101
glucose-6-phosphate 1-dehydrogenase isoform b0101
fructose-bisphosphate aldolase A1001
phosphoethanolamine/phosphocholine phosphatase isoform 10101
perilipin-10101
glucokinase regulatory protein2002
guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 11001
pyruvate kinase PKM isoform a1001
DNA polymerase beta2002
eukaryotic translation initiation factor 4 gamma 1 isoform 40101
serine/threonine-protein kinase PLK12002
histone-lysine N-methyltransferase 2A isoform 2 precursor4004
eukaryotic translation initiation factor 4E isoform 10101
nuclear receptor ROR-gamma isoform 1110011
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a0101
transient receptor potential cation channel subfamily V member 11001
hexokinase HKDC10011
streptokinase A precursor0022
DNA dC->dU-editing enzyme APOBEC-3F isoform a1001
pyruvate kinase PKM isoform b1001
Sulfhydryl oxidase 10101
Acetylcholinesterase0101
Gamma-butyrobetaine dioxygenase0112
Sodium channel protein type 1 subunit alpha1102
Sodium channel protein type 2 subunit alpha1102
Sodium channel protein type 3 subunit alpha1102
Ornithine decarboxylase1001
Macrophage migration inhibitory factor0202
Neutrophil cytosol factor 10101
Insulin-degrading enzyme0101
Indoleamine 2,3-dioxygenase 10303
Urease subunit alpha0202
Toxin B0101
Endothelin receptor type B2002
Endothelin-1 receptor2002
Caspase-10203
Bifunctional epoxide hydrolase 20202
Alpha-synuclein4105
Methionine aminopeptidase 20202
Urease subunit beta0202
Cholinesterase0101
UDP-glucose 4-epimerase0101
Structural capsid protein 0101
Histone deacetylase 90303
Histone deacetylase 50404
2,3-bisphosphoglycerate-independent phosphoglycerate mutase1001
hypothetical protein CAALFM_CR05890CA0001
H3 histone acetyltransferase0001
large T antigen0202
lysosomal alpha-glucosidase preproprotein2002
replicative DNA helicase0001
recombinase A0011
UDP-glucuronosyltransferase 1A90004
UDP-glucuronosyltransferase 2B170001
UDP-glucuronosyltransferase 2B70104
UDP-glucuronosyltransferase 1-60002
UDP-glucuronosyltransferase 1A1 0204
UDP-glucuronosyltransferase 1A70002
GALC protein2002
Estrogen receptor0639
Glucocorticoid receptor012522
Progesterone receptor08312
Androgen receptor07512
Estrogen receptor beta0538
acid sphingomyelinase2002
Type IV secretion-like conjugative transfer relaxase protein TraI 0101
thyrotropin-releasing hormone receptor3003
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a8008
Carbonic anhydrase 120204
Carbonic anhydrase 30203
Glucose-6-phosphate 1-dehydrogenase0404
Carbonic anhydrase 40305
Carbonic anhydrase 60204
Serum paraoxonase/arylesterase 10202
Corticosteroid 11-beta-dehydrogenase isozyme 10101
Carbonic anhydrase 5A, mitochondrial0204
Carbonic anhydrase 70204
Adenosine receptor A10101
Corticosteroid 11-beta-dehydrogenase isozyme 10101
6-phosphogluconate dehydrogenase, decarboxylating0202
Holo-[acyl-carrier-protein] synthase0101
Sodium/bile acid cotransporter0202
Carbonic anhydrase 90204
Multidrug and toxin extrusion protein 10303
Carbonic anhydrase 130203
G-protein coupled receptor 350112
CDGSH iron-sulfur domain-containing protein 10404
Carbonic anhydrase 140204
Carbonic anhydrase 5B, mitochondrial0204
ClpP2002
Transitional endoplasmic reticulum ATPase0101
Chain A, DEOXYNUCLEOSIDE KINASE0101
Equilibrative nucleoside transporter 10101
Aldo-keto reductase family 1 member C30404
Aldo-keto reductase family 1 member C2 0303
Aldo-keto reductase family 1 member C10303
Chain A, GLUTAMATE RECEPTOR SUBUNIT 20101
Chain A, Glutamate Receptor Subunit 20101
Chain B, Glutamate Receptor Subunit 20101
Chain A, Slr1257 protein0011
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]0101
beta-2 adrenergic receptor1001
Metabotropic glutamate receptor 80202
Metabotropic glutamate receptor 60113
Excitatory amino acid transporter 40101
Glutathione reductase, mitochondrial0202
Bifunctional aspartokinase/homoserine dehydrogenase 10101
Prothrombin0113
ATP-citrate synthase 0101
Glutamate receptor 10314
Glutamate receptor 30314
Glutamate receptor 40314
Glutamate receptor ionotropic, kainate 10213
Metabotropic glutamate receptor 10112
Metabotropic glutamate receptor 20011
Metabotropic glutamate receptor 30011
Metabotropic glutamate receptor 40112
Metabotropic glutamate receptor 50011
Metabotropic glutamate receptor 60011
Metabotropic glutamate receptor 70011
Glutamate receptor ionotropic, kainate 10112
Metabotropic glutamate receptor 50113
Glutamate receptor ionotropic, kainate 20213
Glutamate receptor 10213
Glutamate receptor 20213
Glutamate receptor 30112
Glutamate receptor ionotropic, kainate 30202
Excitatory amino acid transporter 10203
Excitatory amino acid transporter 20203
Excitatory amino acid transporter 30203
Metabotropic glutamate receptor 80011
Glutamate receptor 40213
Excitatory amino acid transporter 3 0001
Glutamate racemase0001
Metabotropic glutamate receptor 80112
Glutamate receptor ionotropic, kainate 40202
Glutamate carboxypeptidase 20101
Glutamate receptor ionotropic, kainate 20112
Glutamate receptor ionotropic, kainate 30101
Metabotropic glutamate receptor 10113
Metabotropic glutamate receptor 20113
Metabotropic glutamate receptor 70113
Metabotropic glutamate receptor 30113
Metabotropic glutamate receptor 40113
Glutamate receptor ionotropic, kainate 50101
Carbonic anhydrase-like protein, putative0003
Glutamate receptor ionotropic, kainate 50202
Glutamate racemase0001
Prolyl 4-hydroxylase0101
Alpha-ketoglutarate-dependent dioxygenase FTO0101
Chain A, Glutamine Binding Protein0011
Neutral amino acid transporter A0101
Asc-type amino acid transporter 10101
Neutral amino acid transporter B(0)0101
Amino acid transporter0101
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10203
DNA repair protein RAD52 homolog isoform a0001
Tyrosine-protein kinase ABL10123
Mast/stem cell growth factor receptor Kit0112
Breakpoint cluster region protein0011
Platelet-derived growth factor receptor alpha0112
Cytochrome P450 3A50102
Chain A, membrane-associated prostaglandin E synthase-20101
Parkin4004
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)2002
Prostaglandin E synthase0101
3',5'-cyclic-AMP phosphodiesterase 0202
Cytochrome c oxidase subunit 20101
Phospholipase A2, major isoenzyme0202
Interleukin-80101
Polyunsaturated fatty acid 5-lipoxygenase0203
Aldo-keto reductase family 1 member B10202
Aldo-keto reductase family 1 member B10202
Aldo-keto reductase family 1 member C40101
Prostaglandin G/H synthase 10101
Sodium- and chloride-dependent GABA transporter 10101
Thromboxane-A synthase 0303
Indoleamine 2,3-dioxygenase 10101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Multidrug resistance-associated protein 1 0102
Prostaglandin G/H synthase 2 0101
Peroxisome proliferator-activated receptor gamma0044
Sodium- and chloride-dependent betaine transporter0101
C-X-C chemokine receptor type 30101
Prostaglandin D2 receptor 0202
Solute carrier organic anion transporter family member 1A30103
Lactoylglutathione lyase0101
Prostaglandin G/H synthase 20102
Uracil nucleotide/cysteinyl leukotriene receptor0202
Sigma intracellular receptor 20101
Prostaglandin G/H synthase 1 0101
Dehydrogenase/reductase SDR family member 90101
P2Y purinoceptor 120101
Cytosolic phospholipase A2 gamma0101
Prostaglandin D2 receptor 20112
Estrogen receptor beta0102
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial0101
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial0202
Cytochrome P450 26A10101
Camphor 5-monooxygenase0001
Chymotrypsinogen A0101
Beta-lactamase0101
Steroid 17-alpha-hydroxylase/17,20 lyase0202
Epoxide hydrolase 10001
Cytochrome P450 2C11 0101
Steroid 21-hydroxylase0101
Aromatase0202
Steroid 17-alpha-hydroxylase/17,20 lyase 0101
Cholesterol side-chain cleavage enzyme, mitochondrial 0101
Cytochrome P450 2A20101
Cytochrome P450 11B1, mitochondrial 0202
Cytochrome P450 11B1, mitochondrial0101
Translocator protein0101
Cytochrome P450 7A1 0101
Cytochrome P450 11B2, mitochondrial0101
Estrogen receptor0102
Gonadotropin-releasing hormone receptor0112
Type-1 angiotensin II receptor0101
Malate dehydrogenase, cytoplasmic0101
Cytochrome P450 4F20101
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial0202
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial0101
Lanosterol 14-alpha demethylase0415
Cytochrome P450 7A10101
Lanosterol 14-alpha demethylase 0202
Hsf1 protein0011
Capsid protein 0112
matrix metalloproteinase 1, partial0011
NPC intracellular cholesterol transporter 1 precursor1001
Dihydroorotate dehydrogenase (quinone), mitochondrial0101
Amine oxidase [flavin-containing] A0101
Dihydroorotate dehydrogenase (quinone), mitochondrial0101
Dihydroorotate dehydrogenase (quinone), mitochondrial0101
Angiotensin-converting enzyme 0202
Type-2 angiotensin II receptor0101
Angiotensin-converting enzyme0101
PINK11001
Glycine receptor subunit alpha-1010010
Androgen receptor0011
Glycine receptor subunit beta010010
Glycine receptor subunit alpha-2010010
Glycine receptor subunit alpha-3010010
Chain A, Breast cancer type 1 susceptibility protein1001
microphthalmia-associated transcription factor isoform 90101
Tumor necrosis factor0202
Neuraminidase0101
Platelet-activating factor receptor1001
Cystathionine gamma-lyase0202
Caspase-72002
Cystine/glutamate transporter0101
Hydroxyacid oxidase 10101
Dopamine beta-hydroxylase 0202
Lactoperoxidase0101
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
dopamine D1 receptor3003
Thymidylate synthase 0101
Thymidylate synthase 0101
importin subunit beta-1 isoform 12002
snurportin-12002
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0203
Dihydrofolate reductase0203
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Thymidylate synthase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
High mobility group protein B10022
Dihydrofolate reductase0101
Thymidylate synthase0101
Dihydrofolate reductase0224
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0101
Folate receptor alpha0101
Histidine decarboxylase0101
Trifunctional purine biosynthetic protein adenosine-30101
Cyclin-dependent kinase 20011
Bifunctional purine biosynthesis protein ATIC0202
Mu-type opioid receptor0101
Kappa-type opioid receptor0101
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
Dihydrofolate reductase0101
Pteridine reductase 10101
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Multidrug resistance associated protein0102
Nuclear receptor subfamily 1 group I member 20055
Nuclear receptor subfamily 1 group I member 20011
GTP-binding nuclear protein Ran isoform 11001
Stromelysin-10112
Matrilysin0101
Multidrug transporter MdfA0101
Matrix metalloproteinase-90101
Protein mono-ADP-ribosyltransferase PARP150101
Histone deacetylase 30404
Nuclear receptor corepressor 10101
Integrin beta-10101
Leukotriene A-4 hydrolase0101
Integrin alpha-40101
Histone deacetylase 40303
Histone deacetylase 70303
Histone deacetylase 11 0303
Histone deacetylase 80314
Nuclear receptor corepressor 20101
Transporter0202
Adenosine receptor A30303
Mitogen-activated protein kinase 140101
Leukotriene C4 synthase0101
Cysteinyl leukotriene receptor 10101
Cysteinyl leukotriene receptor 20101
Cysteinyl leukotriene receptor 10213
DNA gyrase subunit B0101
DNA gyrase subunit A0102
DNA gyrase subunit B0102
DNA topoisomerase 4 subunit A0101
DNA gyrase subunit B0101
DNA topoisomerase 2-alpha0001
Potassium voltage-gated channel subfamily E member 10101
DNA gyrase subunit A0101
Potassium voltage-gated channel subfamily KQT member 10101
DNA gyrase subunit B0203
DNA gyrase subunit A0203
Chain A, Inosine-5'-Monophosphate Dehydrogenase 20101
Inosine-5'-monophosphate dehydrogenase 20202
Inosine-5'-monophosphate dehydrogenase 1 0202
Inosine-5'-monophosphate dehydrogenase0102
UDP-glucuronosyltransferase 1A100001
UDP-glucuronosyltransferase 1A80001
Trace amine-associated receptor 10011
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10001
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10001
Voltage-dependent L-type calcium channel subunit beta-40101
Voltage-dependent P/Q-type calcium channel subunit alpha-1A0101
Voltage-dependent T-type calcium channel subunit alpha-1G0101
Voltage-dependent calcium channel gamma-3 subunit0101
Voltage-dependent T-type calcium channel subunit alpha-1H0101
Cannabinoid receptor 10202
Voltage-dependent L-type calcium channel subunit beta-30101
Voltage-dependent calcium channel subunit alpha-2/delta-10101
Voltage-dependent calcium channel gamma-7 subunit0101
Voltage-dependent N-type calcium channel subunit alpha-1B0101
Voltage-dependent L-type calcium channel subunit beta-10101
Voltage-dependent calcium channel gamma-1 subunit0101
Voltage-dependent L-type calcium channel subunit beta-20101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
Voltage-dependent R-type calcium channel subunit alpha-1E0101
Voltage-dependent calcium channel subunit alpha-2/delta-40101
Transient receptor potential cation channel subfamily A member 10011
Voltage-dependent calcium channel subunit alpha-2/delta-30101
Voltage-dependent calcium channel gamma-8 subunit0101
Bile acid receptor0202
Voltage-dependent calcium channel gamma-6 subunit0101
Voltage-dependent calcium channel subunit alpha-2/delta-20101
Voltage-dependent T-type calcium channel subunit alpha-1I0101
Voltage-dependent calcium channel gamma-4 subunit0101
Voltage-dependent calcium channel gamma-5 subunit0101
Voltage-dependent calcium channel gamma-2 subunit0101
Carbonic anhydrase0102
Sodium/iodide cotransporter0101
Carbonic anhydrase 150203
FAD-linked sulfhydryl oxidase ALR0001
Alpha-1A adrenergic receptor0101
Chain A, Bacterial leucyl aminopeptidase0101
90-kda heat shock protein beta HSP90 beta, partial0101
heat shock protein HSP 90-alpha isoform 20102
26S proteasome non-ATPase regulatory subunit 140101
Thermolysin0203
Cholinesterase0202
72 kDa type IV collagenase0101
Botulinum neurotoxin type A 0101
Catechol O-methyltransferase0101
Catechol O-methyltransferase0101
Methionine aminopeptidase 10101
Glutaminyl-peptide cyclotransferase0101
Vasopressin V2 receptor0112
Oxytocin receptor0224
Vasopressin V1a receptor0101
Vasopressin V1a receptor0213
Vasopressin V1b receptor0112
Vasopressin V1b receptor0101
Oxytocin receptor0101
Oxytocin receptor0011
Vasopressin V2 receptor 0101
Beta-lactamase 0001
Beta-lactamase0001
Solute carrier family 22 member 80102
Beta-lactamase0001
Beta-lactamase 10001
Beta-lactamase0001
Beta-lactamase OXA-100001
Beta-lactamase0001
Beta-lactamase TEM0102
Beta-lactamase0001
Efflux transporter 0001
Beta-lactamase 0001
Class D beta-lactamase0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase IMP-1 0001
Beta-lactamase 0001
vasopressin V1b receptor1001
relaxin receptor 1 isoform 11001
cGMP-dependent 3',5'-cyclic phosphodiesterase0101
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A0101
cGMP-specific 3',5'-cyclic phosphodiesterase0101
Adenosine receptor A2b0101
Chitotriosidase-10213
cGMP-inhibited 3',5'-cyclic phosphodiesterase A0101
Endochitinase B10213
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b0011
luciferase0001
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Glutamine synthetase0011
Nociceptin receptor0011
heat shock protein 90, putative0001
NADH-cytochrome b5 reductase 3 0101
Thyroid peroxidase0101
Taste receptor type 2 member 380012
DNA-directed RNA polymerase subunit beta0101
Solute carrier organic anion transporter family member 1A40102
NH(3)-dependent NAD(+) synthetase0101
Arylacetamide deacetylase0102
Solute carrier organic anion transporter family member 1A20102
Glutathione S-transferase omega-10101
Enoyl-[acyl-carrier-protein] reductase [NADH]0101
DNA-directed RNA polymerase subunit beta0101
chaperonin-containing TCP-1 beta subunit homolog1001
Inhibitor of nuclear factor kappa-B kinase subunit beta0001
5'-AMP-activated protein kinase subunit beta-20001
Polymerase acidic protein0011
Tyrosine-protein phosphatase YopH0101
Prolyl 4-hydroxylase subunit alpha-10101
Tyrosine-protein phosphatase non-receptor type 10103
5'-AMP-activated protein kinase subunit gamma-10001
5'-AMP-activated protein kinase catalytic subunit alpha-20001
5'-AMP-activated protein kinase catalytic subunit alpha-10001
Carbonic anhydrase0101
Ubiquitin-like domain-containing CTD phosphatase 10101
5'-AMP-activated protein kinase subunit gamma-30001
5'-AMP-activated protein kinase subunit gamma-20001
5'-AMP-activated protein kinase subunit beta-10001
Chain A, Mineralocorticoid receptor0101
Chain A, Mineralocorticoid receptor0101
Vpr1001
Tyrosinase0101
NAD(P)H dehydrogenase [quinone] 10001
Serine/threonine-protein kinase mTOR0101
Peptidyl-prolyl cis-trans isomerase FKBP1A0213
Peptidyl-prolyl cis-trans isomerase FKBP1B0011
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform0101
Peptidyl-prolyl cis-trans isomerase FKBP50101
Splicing factor 3B subunit 30101
NS3 protease 0203
Cathepsin L20101
Plasminogen0102
Trypsin-10101
Cathepsin B0101
Neutrophil elastase0102
Chymase0101
Cathepsin S0102
Cathepsin K0101
NS3 protease 0101
Cathepsin F0101
Chymotrypsin-like elastase family member 10101
Cereblon isoform 40202
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0101
DNA-binding protein Ikaros0001
DNA damage-binding protein 10112
Protein cereblon0214
Chain X, Thyroid hormone receptor beta-10011
Chain X, Thyroid hormone receptor beta-10011
Rap guanine nucleotide exchange factor 31001
Transthyretin0102
Thyroid hormone receptor alpha0011
Thyroid hormone receptor beta0011
Proliferating cell nuclear antigen0101
Retinoic acid receptor RXR-alpha0022
Malate dehydrogenase, mitochondrial0101
Solute carrier organic anion transporter family member 4C10101
Monocarboxylate transporter 80001
Solute carrier organic anion transporter family member 1C10001
Chain A, CHORISMATE MUTASE0101
Chain A, TYROSYL-tRNA SYNTHETASE0011
Carbonic anhydrase0001
Large neutral amino acids transporter small subunit 10202
SLC16A10 protein0001
Carbonic anhydrase 0001
Carbonic anhydrase0001
Carbonic anhydrase0001
Carbonic anhydrase 0001
Tubulin--tyrosine ligase0101
Monocarboxylate transporter 100001
Taste receptor type 2 member 140001
Insulin-like growth factor 1 receptor0011
Valacyclovir hydrolase0001
Chain A, Arginase 10101
Cocaine esterase0101
Tissue factor0101
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member B70101
Polyamine deacetylase HDAC100202
NAD-dependent protein deacylase sirtuin-5, mitochondrial0101
D-alanyl-D-alanine dipeptidase0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]