| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION | 0 | 0 | 1 | 1 |
| Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION | 0 | 0 | 1 | 1 |
| Chain H, Fab M82G2, Heavy chain | 0 | 0 | 1 | 1 |
| Chain L, Fab M82G2, Light chain | 0 | 0 | 1 | 1 |
| Chain H, Fab M82g2, Heavy Chain | 0 | 0 | 1 | 1 |
| Chain L, Fab M82g2, Light Chain | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | 0 | 1 | 0 | 1 |
| Amyloid-beta precursor protein | 0 | 1 | 0 | 1 |
| Fatty acid-binding protein, heart | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M2 | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M1 | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 2C | 0 | 2 | 0 | 2 |
| Tryptophan 5-hydroxylase 1 | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 2A | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 0 | 1 | 0 | 1 |
| D | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 1A | 0 | 1 | 0 | 1 |
| Alpha-2B adrenergic receptor | 0 | 1 | 0 | 1 |
| Alpha-2C adrenergic receptor | 0 | 1 | 0 | 1 |
| Alpha-2A adrenergic receptor | 0 | 1 | 0 | 1 |
| Liver carboxylesterase 1 | 0 | 0 | 0 | 1 |
| Sodium-dependent noradrenaline transporter | 0 | 4 | 0 | 4 |
| Sodium-dependent dopamine transporter | 0 | 2 | 0 | 2 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 1B | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 1D | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 1F | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 2B | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 6 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 0 | 1 | 0 | 1 |
| Sodium-dependent serotonin transporter | 0 | 2 | 0 | 2 |
| Sodium-dependent serotonin transporter | 0 | 2 | 0 | 3 |
| 5-hydroxytryptamine receptor 7 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 5A | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 5B | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 3A | 0 | 1 | 0 | 1 |
| Lysosomal Pro-X carboxypeptidase | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 0 | 1 | 0 | 1 |
| D(2) dopamine receptor | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 2A | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 2B | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 2C | 0 | 1 | 0 | 1 |
| Sodium-dependent dopamine transporter | 0 | 2 | 0 | 2 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 0 | 1 | 0 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 0 | 1 | 0 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | 0 | 2 | 0 | 2 |
| Leukotriene B4 receptor 1 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 0 | 1 | 0 | 1 |
| Sodium-dependent dopamine transporter | 0 | 2 | 0 | 2 |
| Glutamate receptor ionotropic, NMDA 2D | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 4 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 3B | 0 | 1 | 0 | 1 |
| Sigma non-opioid intracellular receptor 1 | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 3B | 0 | 1 | 0 | 1 |
| Leukotriene B4 receptor 2 | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 3A | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit theta | 0 | 1 | 0 | 1 |
| Transporter | 0 | 2 | 0 | 2 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 1 | 0 | 0 | 1 |
| Chain A, Beta-lactamase | 1 | 0 | 0 | 1 |
| thioredoxin reductase | 1 | 0 | 0 | 1 |
| RAR-related orphan receptor gamma | 2 | 0 | 0 | 2 |
| GLS protein | 1 | 0 | 0 | 1 |
| TDP1 protein | 2 | 0 | 0 | 2 |
| Microtubule-associated protein tau | 1 | 0 | 0 | 1 |
| AR protein | 2 | 0 | 0 | 2 |
| aldehyde dehydrogenase 1 family, member A1 | 1 | 0 | 0 | 1 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | 1 | 0 | 0 | 1 |
| IDH1 | 1 | 0 | 0 | 1 |
| euchromatic histone-lysine N-methyltransferase 2 | 1 | 0 | 0 | 1 |
| chromobox protein homolog 1 | 1 | 0 | 0 | 1 |
| mitogen-activated protein kinase 1 | 1 | 0 | 0 | 1 |
| flap endonuclease 1 | 1 | 0 | 0 | 1 |
| geminin | 1 | 0 | 0 | 1 |
| cytochrome P450 3A4 isoform 1 | 1 | 0 | 0 | 1 |
| muscarinic acetylcholine receptor M1 | 1 | 0 | 0 | 1 |
| lamin isoform A-delta10 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | 1 | 0 | 0 | 1 |
| Potassium channel subfamily K member 3 | 0 | 1 | 0 | 1 |
| ATP-binding cassette sub-family C member 3 | 0 | 3 | 0 | 3 |
| Multidrug resistance-associated protein 4 | 0 | 3 | 0 | 3 |
| Potassium channel subfamily K member 2 | 0 | 1 | 0 | 1 |
| Bile salt export pump | 0 | 3 | 0 | 3 |
| Sodium channel protein type 1 subunit alpha | 0 | 1 | 0 | 1 |
| Sodium channel protein type 2 subunit alpha | 0 | 1 | 0 | 1 |
| Sodium channel protein type 3 subunit alpha | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 1 | 0 | 0 | 1 |
| Potassium voltage-gated channel subfamily A member 5 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 1 | 0 | 0 | 1 |
| Sodium channel protein type 4 subunit alpha | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 1 | 0 | 0 | 1 |
| Sodium channel protein type 5 subunit alpha | 0 | 1 | 0 | 1 |
| Sodium channel protein type 9 subunit alpha | 0 | 1 | 0 | 1 |
| Potassium voltage-gated channel subfamily D member 2 | 0 | 1 | 0 | 1 |
| Potassium channel subfamily K member 18 | 0 | 1 | 0 | 1 |
| GABA theta subunit | 1 | 0 | 0 | 1 |
| Canalicular multispecific organic anion transporter 1 | 0 | 3 | 0 | 3 |
| Multidrug and toxin extrusion protein 1 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | 1 | 0 | 0 | 1 |
| Sodium channel protein type 3 subunit alpha | 0 | 1 | 0 | 1 |
| luciferase | 0 | 0 | 0 | 1 |
| hypoxia-inducible factor 1 alpha subunit | 1 | 0 | 0 | 1 |
| GLI family zinc finger 3 | 1 | 0 | 0 | 1 |
| progesterone receptor | 1 | 0 | 0 | 1 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 1 | 0 | 0 | 1 |
| glucocorticoid receptor [Homo sapiens] | 1 | 0 | 0 | 1 |
| retinoic acid nuclear receptor alpha variant 1 | 1 | 0 | 0 | 1 |
| estrogen-related nuclear receptor alpha | 1 | 0 | 0 | 1 |
| pregnane X nuclear receptor | 1 | 0 | 0 | 1 |
| estrogen nuclear receptor alpha | 2 | 0 | 0 | 2 |
| aryl hydrocarbon receptor | 1 | 0 | 0 | 1 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 1 | 0 | 0 | 1 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | 1 | 0 | 0 | 1 |
| nuclear receptor subfamily 1, group I, member 2 | 1 | 0 | 0 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | 1 | 0 | 0 | 1 |
| Voltage-dependent calcium channel gamma-2 subunit | 1 | 0 | 0 | 1 |
| Interferon beta | 1 | 0 | 0 | 1 |
| Fatty acid-binding protein, liver | 0 | 1 | 0 | 1 |
| Estrogen receptor | 0 | 2 | 0 | 2 |
| Glucocorticoid receptor | 0 | 2 | 1 | 8 |
| Cellular tumor antigen p53 | 1 | 0 | 0 | 1 |
| Progesterone receptor | 0 | 2 | 0 | 3 |
| Glucocorticoid receptor | 0 | 1 | 1 | 2 |
| Glucocorticoid receptor | 0 | 0 | 1 | 1 |
| Glycine receptor subunit alpha-1 | 0 | 2 | 0 | 2 |
| Corticosteroid-binding globulin | 0 | 1 | 0 | 1 |
| Mineralocorticoid receptor | 0 | 2 | 1 | 3 |
| Androgen receptor | 0 | 2 | 0 | 2 |
| Cytochrome P450 2C9 | 0 | 1 | 0 | 1 |
| Glutamine synthetase | 0 | 0 | 1 | 1 |
| Androgen receptor | 0 | 1 | 0 | 1 |
| Glutamate receptor 2 | 1 | 0 | 0 | 1 |
| Glycine receptor subunit beta | 0 | 2 | 0 | 2 |
| Glycine receptor subunit alpha-2 | 0 | 2 | 0 | 2 |
| Glycine receptor subunit alpha-3 | 0 | 2 | 0 | 2 |
| Histamine H1 receptor | 0 | 0 | 1 | 1 |
| Prostaglandin G/H synthase 2 | 0 | 1 | 0 | 1 |
| Nociceptin receptor | 0 | 0 | 1 | 1 |
| Cytochrome P450 2J2 | 0 | 1 | 0 | 1 |
| Estrogen receptor beta | 0 | 2 | 0 | 2 |
| ATPase family AAA domain-containing protein 5 | 1 | 0 | 0 | 1 |
| Ataxin-2 | 1 | 0 | 0 | 1 |
| EWS/FLI fusion protein | 1 | 0 | 0 | 1 |
| Voltage-dependent calcium channel subunit alpha-2/delta-1 | 0 | 1 | 0 | 2 |
| Voltage-dependent calcium channel subunit alpha-2/delta-2 | 0 | 1 | 0 | 1 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |