Piscirickettsiaceae Infections

Infections with bacteria of the family PISCIRICKETTSIACEAE, causing septicemic disease of salmonid fish (SALMONIDAE). Piscirickettsia-like bacteria are also associated with disease syndromes in non-salmonid fish.

Synonyms(2)

Synonym
Piscirickettsiosis
Piscirickettsiaceae Infections

Research Excerpts

Overview

Excerpt	Reference
"Piscirickettsiosis is a fish disease caused by the facultative intracellular bacterium, Piscirickettsia salmonis."	( Avendaño-Herrera, R; Levipan, HA, 2021)

Context

Excerpt	Reference
"Diagnosis of piscirickettsiosis has traditionally been based upon identification of typical pathological changes by histological investigation, with confirmation by immunohistochemistry on formalin-fixed, paraffin-embedded tissues."	( Bordevik, M; Colquhoun, DJ; Karatas, S; Mikalsen, J; Steinum, TM; Taksdal, T, 2008)

Research

Studies (28)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	0 (0.00)	23.3326
1990's	0 (0.00)	12.5806
2000's	7 (25.00)	18.1394
2010's	13 (46.43)	28.8240
2020's	8 (28.57)	9.53

Drug	Relationship Strength	Studies
formaldehyde	low	1
nitrates	low	1
deferoxamine	low	1
guaifenesin	low	2
iodixanol	low	1
carbostyril	low	1
gold	low	1
ferric nitrate	low	1
thiamphenicol	low	5
florfenicol	low	5
glycogen	low	1
selenium	low	1
chitosan	low	1
oxytetracycline, anhydrous	low	3
agar	low	2
bassianolide	low	3
ferric ammonium citrate	low	1

Protein Targets (163)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, Putative fructose-1,6-bisphosphate aldolase	2	0	0	2
Chain A, serum paraoxonase	0	1	0	1
nuclear receptor ROR-gamma isoform 1	1	0	0	1
DNA polymerase kappa isoform 1	2	0	0	2
Carbonic anhydrase 12	0	1	0	1
Carbonic anhydrase 1	0	2	0	2
Carbonic anhydrase 2	0	2	0	2
Carbonic anhydrase 3	0	1	0	1
Neutrophil cytosol factor 1	0	1	0	1
Carbonic anhydrase 4	0	2	0	2
Carbonic anhydrase 6	0	1	0	1
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Carbonic anhydrase 7	0	1	0	1
Carbonic anhydrase 9	0	1	0	1
Carbonic anhydrase 13	0	1	0	1
Poly [ADP-ribose] polymerase tankyrase-2	0	1	0	1
Carbonic anhydrase 14	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	1	0	1
TDP1 protein	3	0	0	3
apical membrane antigen 1, AMA1	2	0	0	2
67.9K protein	1	0	0	1
IDH1	1	0	0	1
nuclear factor erythroid 2-related factor 2 isoform 2	1	0	0	1
DNA polymerase iota isoform a (long)	3	0	0	3
urokinase-type plasminogen activator precursor	1	0	0	1
plasminogen precursor	1	0	0	1
urokinase plasminogen activator surface receptor precursor	1	0	0	1
geminin	3	0	0	3
Lysine-specific demethylase 4A	0	1	0	1
Guanine nucleotide-binding protein G	1	0	0	1
Hypoxia-inducible factor 1-alpha	0	0	1	1
Methylcytosine dioxygenase TET2	0	1	0	1
Deoxyhypusine hydroxylase	0	1	0	1
GLI family zinc finger 3	1	0	0	1
nuclear receptor subfamily 1, group I, member 3	2	0	0	2
estrogen-related nuclear receptor alpha	2	0	0	2
estrogen nuclear receptor alpha	2	0	0	2
transcriptional regulator ERG isoform 3	2	0	0	2
twin arginine protein translocation system - TatA protein	0	0	0	1
30S ribosomal protein S6	0	1	0	1
30S ribosomal protein S7	0	1	0	1
50S ribosomal protein L15	0	1	0	1
50S ribosomal protein L10	0	1	0	1
50S ribosomal protein L11	0	1	0	1
50S ribosomal protein L7/L12	0	1	0	1
50S ribosomal protein L19	0	1	0	1
50S ribosomal protein L1	0	1	0	1
50S ribosomal protein L20	0	1	0	1
50S ribosomal protein L27	0	1	0	1
50S ribosomal protein L28	0	1	0	1
50S ribosomal protein L29	0	1	0	1
50S ribosomal protein L31	0	1	0	1
50S ribosomal protein L31 type B	0	1	0	1
50S ribosomal protein L32	0	1	0	1
50S ribosomal protein L33	0	1	0	1
50S ribosomal protein L34	0	1	0	1
50S ribosomal protein L35	0	1	0	1
50S ribosomal protein L36	0	1	0	1
30S ribosomal protein S10	0	1	0	1
30S ribosomal protein S11	0	1	0	1
30S ribosomal protein S12	0	1	0	1
30S ribosomal protein S13	0	1	0	1
30S ribosomal protein S16	0	1	0	1
30S ribosomal protein S18	0	1	0	1
30S ribosomal protein S19	0	1	0	1
30S ribosomal protein S20	0	1	0	1
30S ribosomal protein S2	0	1	0	1
30S ribosomal protein S3	0	1	0	1
30S ribosomal protein S4	0	1	0	1
30S ribosomal protein S5	0	1	0	1
30S ribosomal protein S8	0	1	0	1
30S ribosomal protein S9	0	1	0	1
50S ribosomal protein L13	0	1	0	1
50S ribosomal protein L14	0	1	0	1
50S ribosomal protein L16	0	1	0	1
50S ribosomal protein L23	0	1	0	1
30S ribosomal protein S15	0	1	0	1
50S ribosomal protein L17	0	1	0	1
50S ribosomal protein L21	0	1	0	1
50S ribosomal protein L30	0	1	0	1
50S ribosomal protein L6	0	1	0	1
30S ribosomal protein S14	0	1	0	1
30S ribosomal protein S17	0	1	0	1
30S ribosomal protein S1	0	1	0	1
50S ribosomal protein L18	0	1	0	1
50S ribosomal protein L2	0	1	0	1
50S ribosomal protein L3	0	1	0	1
50S ribosomal protein L24	0	1	0	1
50S ribosomal protein L4	0	1	0	1
50S ribosomal protein L22	0	1	0	1
50S ribosomal protein L5	0	1	0	1
30S ribosomal protein S21	0	1	0	1
50S ribosomal protein L25	0	1	0	1
50S ribosomal protein L36 2	0	1	0	1
SMAD family member 2	1	0	0	1
SMAD family member 3	1	0	0	1
farnesoid X nuclear receptor	1	0	0	1
flap endonuclease 1	2	0	0	2
Bile salt export pump	0	2	0	2
Rap guanine nucleotide exchange factor 3	2	0	0	2
RAR-related orphan receptor gamma	1	0	0	1
cytochrome P450 family 3 subfamily A polypeptide 4	2	0	0	2
Cellular tumor antigen p53	1	0	0	1
Carbonic anhydrase	0	1	0	1
Sodium/iodide cotransporter	0	1	0	1
Carbonic anhydrase 15	0	1	0	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	1	0	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	1	0	0	1
Chain A, Beta-lactamase	1	0	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	1	0	0	1
Chain A, 2-oxoglutarate Oxygenase	1	0	0	1
Chain A, ATP-DEPENDENT DNA HELICASE Q1	1	0	0	1
thioredoxin reductase	1	0	0	1
WRN	1	0	0	1
phosphopantetheinyl transferase	1	0	0	1
USP1 protein, partial	1	0	0	1
GLS protein	1	0	0	1
Microtubule-associated protein tau	1	0	0	1
Valosin-containing protein	0	1	0	1
AR protein	1	0	0	1
thioredoxin glutathione reductase	1	0	0	1
aldehyde dehydrogenase 1 family, member A1	1	0	0	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	1	0	0	1
regulator of G-protein signaling 4	1	0	0	1
pregnane X nuclear receptor	1	0	0	1
cytochrome P450 2D6	2	0	0	2
bromodomain adjacent to zinc finger domain 2B	1	0	0	1
euchromatic histone-lysine N-methyltransferase 2	1	0	0	1
aryl hydrocarbon receptor	1	0	0	1
thyroid stimulating hormone receptor	1	0	0	1
v-jun sarcoma virus 17 oncogene homolog (avian)	1	0	0	1
Histone H2A.x	1	0	0	1
lysosomal alpha-glucosidase preproprotein	1	0	0	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	1	0	0	1
vitamin D3 receptor isoform VDRA	1	0	0	1
chromobox protein homolog 1	2	0	0	2
thyroid hormone receptor beta isoform a	1	0	0	1
microphthalmia-associated transcription factor isoform 9	0	1	0	1
importin subunit beta-1 isoform 1	1	0	0	1
DNA polymerase beta	1	0	0	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	1	0	0	1
eukaryotic translation initiation factor 4 gamma 1 isoform 4	0	1	0	1
serine/threonine-protein kinase PLK1	1	0	0	1
snurportin-1	1	0	0	1
nuclear factor erythroid 2-related factor 2 isoform 1	1	0	0	1
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	1	0	0	1
DNA polymerase eta isoform 1	1	0	0	1
eukaryotic translation initiation factor 4E isoform 1	0	1	0	1
muscleblind-like protein 1 isoform 1	1	0	0	1
histone acetyltransferase KAT2A isoform 1	1	0	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	0	0	1
Neuronal acetylcholine receptor subunit alpha-4	1	0	0	1
Neuronal acetylcholine receptor subunit beta-2	1	0	0	1
Serum paraoxonase/arylesterase 1	0	1	0	1
phosphoglycerate kinase	1	0	0	1
EWS/FLI fusion protein	1	0	0	1
retinoid X nuclear receptor alpha	1	0	0	1
streptokinase A precursor	0	0	1	1
ATP-binding cassette sub-family C member 3	0	1	0	1
Multidrug resistance-associated protein 4	0	1	0	1
Estrogen receptor	0	0	1	1
Estrogen receptor beta	0	0	1	1
Canalicular multispecific organic anion transporter 1	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

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