Page last updated: 2024-09-27

Phonological Disorder

Persistent difficulty with speech sound production such that it interferes with verbal communication.

Synonyms(2)

Synonym
Phonological Disorder
Speech Sound Disorder

Research

Studies (7)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's0 (0.00)12.5806
2000's0 (0.00)18.1394
2010's4 (57.14)28.8240
2020's3 (42.86)9.53
DrugIndicatedRelationship StrengthStudiesTrials
guaifenesin0low10
glutamine0low10
inositol 3-phosphate0medium31

Protein Targets (25)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, Glutamine Binding Protein0011
thioredoxin reductase1001
15-lipoxygenase, partial1001
GLS protein1001
arylsulfatase A1001
euchromatic histone-lysine N-methyltransferase 21001
Bloom syndrome protein isoform 11001
peripheral myelin protein 22 isoform 11001
flap endonuclease 12002
histone-lysine N-methyltransferase 2A isoform 2 precursor1001
Carbonic anhydrase 10001
Carbonic anhydrase 20001
Neutral amino acid transporter A0101
Asc-type amino acid transporter 10101
Neutral amino acid transporter B(0)0101
Carbonic anhydrase-like protein, putative0001
Amino acid transporter0101
ATP-dependent phosphofructokinase1001
SMAD family member 21001
SMAD family member 31001
nuclear receptor subfamily 1, group I, member 31001
farnesoid X nuclear receptor1001
geminin1001
Bile salt export pump0101
Rap guanine nucleotide exchange factor 31001
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]