Page last updated: 2024-09-27

Peste-des-Petits-Ruminants

A highly fatal contagious disease of goats and sheep caused by PESTE-DES-PETITS-RUMINANTS VIRUS. The disease may be acute or subacute and is characterized by stomatitis, conjunctivitis, diarrhea, and pneumonia.

Synonyms(2)

Synonym
Pseudorinderpest
Peste-des-Petits-Ruminants

Research

Studies (68)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's0 (0.00)12.5806
2000's12 (17.65)18.1394
2010's37 (54.41)28.8240
2020's19 (27.94)9.53
DrugIndicatedRelationship StrengthStudiesTrials
formaldehyde0low10
uracil0low10
chloroquine0low10
leflunomide0low10
2-naphthol0low10
silver0low10
cerium0low10
gold0low20
ammonium chloride0low10
ribavirin0low20
brequinar0low10
azauracil0low10
nsc-1727550low10
biotin0low30
wortmannin0low10
n-acetylneuraminic acid0low10
mycophenolic acid0low10
ovalbumin0low10
phenylephrine hydrochloride0low40
morantel0low10
cellulose0low10
sybr green i0low30
guanosine triphosphate0low10
guanosine0low10
eye0low60
concanavalin a0low10

Protein Targets (313)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Luciferase2002
RAR-related orphan receptor gamma7007
GLI family zinc finger 34004
AR protein5005
estrogen receptor 2 (ER beta)2002
nuclear receptor subfamily 1, group I, member 34004
progesterone receptor3003
retinoic acid nuclear receptor alpha variant 13003
retinoid X nuclear receptor alpha3003
pregnane X nuclear receptor3003
estrogen nuclear receptor alpha7007
peroxisome proliferator-activated receptor delta3003
aryl hydrocarbon receptor3003
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a4004
v-jun sarcoma virus 17 oncogene homolog (avian)2002
Histone H2A.x3003
thyroid hormone receptor beta isoform 24004
nuclear factor erythroid 2-related factor 2 isoform 15005
DNA repair and recombination protein RadA0011
Voltage-dependent calcium channel gamma-2 subunit5005
Cellular tumor antigen p534004
Cytochrome P450 1A20202
Cytochrome P450 2A60101
Sulfotransferase 1A1 0001
Glutamate receptor 25106
Cytochrome P450 2A50101
Sulfotransferase 1E10001
Sulfotransferase 1A10001
Sulfotransferase 2A10001
Chain A, Avidin0011
Chain A, Protein (streptavidin)0011
Chain B, Protein (streptavidin)0011
Chain A, Streptavidin0011
Chain D, Streptavidin0011
Chain A, Streptavidin0011
Chain D, Streptavidin0011
Chain A, Streptavidin0011
Chain D, Streptavidin0011
Chain A, Streptavidin Complex With Biotin0011
Chain D, Circularly Permuted Core-streptavidin E51/a460011
Chain A, Core-streptavidin0011
Chain D, Core-streptavidin0011
Chain A, Core-streptavidin0011
Chain D, Core-streptavidin0011
Chain A, Core-streptavidin0011
Chain D, Core-streptavidin0011
Chain A, Core-streptavidin0011
Chain D, Core-streptavidin0011
Chain A, Avidin0011
Chain A, Streptavidin0011
Chain B, Streptavidin0011
Chain A, Streptavidin0011
Chain B, Streptavidin0011
Chain A, JmjC domain-containing histone demethylation protein 3A1001
apical membrane antigen 1, AMA11001
nonstructural protein 10101
green fluorescent protein, partial0101
vitamin D3 receptor isoform VDRA2002
insulin-degrading enzyme isoform 10011
Streptavidin0011
Receptor-type tyrosine-protein phosphatase beta0001
Dihydroorotate dehydrogenase 0101
Dihydrofolate reductase0101
Dihydroorotate dehydrogenase (quinone), mitochondrial0202
Dihydroorotate dehydrogenase (quinone), mitochondrial0202
thioredoxin reductase3003
PPM1D protein2002
TDP1 protein7007
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase0101
euchromatic histone-lysine N-methyltransferase 24004
Spike glycoprotein0123
Replicase polyprotein 1ab0123
glucose-6-phosphate 1-dehydrogenase isoform b0101
flap endonuclease 11001
Transmembrane protease serine 20123
ATP-binding cassette sub-family C member 30404
Multidrug resistance-associated protein 40404
Bile salt export pump0404
Dihydrofolate reductase 0101
DNA ligase0101
Interferon beta2002
Riboflavin-binding protein0011
Major prion protein0011
Amyloid-beta precursor protein0101
Histidine-rich protein PFHRP-II0102
Procathepsin L0123
Muscarinic acetylcholine receptor M20101
Muscarinic acetylcholine receptor M40101
Cytochrome P450 3A40101
Muscarinic acetylcholine receptor M50101
Alpha-2A adrenergic receptor0101
Replicase polyprotein 1a0123
Replicase polyprotein 1ab0123
Replicase polyprotein 1ab0123
Spike glycoprotein0101
Replicase polyprotein 1ab0123
Muscarinic acetylcholine receptor M10101
Ribosyldihydronicotinamide dehydrogenase [quinone]0101
Alpha-2B adrenergic receptor0101
Alpha-2C adrenergic receptor0101
DNA ligase 10101
Muscarinic acetylcholine receptor M30101
Serine/threonine-protein kinase mTOR0213
Nuclear receptor subfamily 4 group A member 20011
Beta-secretase 10101
Spike glycoprotein1124
Calcium-dependent protein kinase 10011
MO15-related protein kinase Pfmrk 0101
DNA ligase A0101
Potassium voltage-gated channel subfamily H member 20202
Sigma intracellular receptor 20101
Phosphoethanolamine N-methyltransferase0101
Canalicular multispecific organic anion transporter 10404
Ataxin-24004
Sigma non-opioid intracellular receptor 10101
Angiotensin-converting enzyme 2 0123
Cysteine proteinase falcipain 2a 0101
Cysteine proteinase falcipain 2a 0101
Chain A, Membrane lipoprotein tmpC0011
Chain A, Membrane lipoprotein tmpC0011
Chain A, Membrane lipoprotein tmpC0011
Chain A, ATP-DEPENDENT DNA HELICASE Q12002
Purine nucleoside phosphorylase0001
Adenosylhomocysteinase0104
Chain A, Uracil Phosphoribosyltransferase0011
Chain B, Uracil Phosphoribosyltransferase0011
Chain C, Uracil Phosphoribosyltransferase0011
phosphopantetheinyl transferase3003
67.9K protein3003
2-dehydropantoate 2-reductase0011
Ras-related protein Rab-7a0011
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 90202
acetylcholinesterase2002
glp-1 receptor, partial3003
matrix metalloproteinase 1, partial0011
hypoxia-inducible factor 1 alpha subunit1001
ATAD5 protein, partial1001
Fumarate hydratase1001
USP1 protein, partial1001
Thrombopoietin2002
caspase 7, apoptosis-related cysteine protease1001
cytochrome P450 family 3 subfamily A polypeptide 42002
EWS/FLI fusion protein1001
nonstructural protein 11001
glucocorticoid receptor [Homo sapiens]3003
estrogen-related nuclear receptor alpha4004
farnesoid X nuclear receptor3003
G1001
cytochrome P450 2D61001
polyprotein1001
Parkin1001
P531001
vitamin D (1,25- dihydroxyvitamin D3) receptor2002
arylsulfatase A2002
pyruvate kinase1001
caspase-31001
IDH13003
activating transcription factor 62002
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a2002
nuclear receptor subfamily 1, group I, member 21001
Bloom syndrome protein isoform 12002
NPC intracellular cholesterol transporter 1 precursor1001
peripheral myelin protein 22 isoform 12002
cellular tumor antigen p53 isoform a1001
cytochrome P450 2C19 precursor1001
cytochrome P450 2C9 precursor1001
thyroid hormone receptor beta isoform a2002
nuclear factor erythroid 2-related factor 2 isoform 24004
histone deacetylase 9 isoform 31001
heat shock protein beta-11001
huntingtin isoform 21001
ras-related protein Rab-9A1001
DNA polymerase iota isoform a (long)2002
urokinase-type plasminogen activator precursor3003
plasminogen precursor3003
urokinase plasminogen activator surface receptor precursor3003
nuclear receptor ROR-gamma isoform 11001
geminin6006
peripheral myelin protein 223003
survival motor neuron protein isoform d3003
cytochrome P450 3A4 isoform 13003
histone acetyltransferase KAT2A isoform 11001
muscarinic acetylcholine receptor M12002
lamin isoform A-delta104004
neuropeptide S receptor isoform A1001
Gamma-aminobutyric acid receptor subunit pi3003
Dihydroorotate dehydrogenase (quinone), mitochondrial0101
Bile salt export pump0101
HLA class I histocompatibility antigen, B alpha chain 1001
Integrin beta-31001
Aldo-keto reductase family 1 member B10202
Integrin alpha-IIb1001
Gamma-aminobutyric acid receptor subunit beta-13003
Gamma-aminobutyric acid receptor subunit delta3003
Gamma-aminobutyric acid receptor subunit gamma-23003
Gamma-aminobutyric acid receptor subunit alpha-53003
Gamma-aminobutyric acid receptor subunit alpha-33003
Amine oxidase [flavin-containing] A0101
Endothelin receptor type B1001
Gamma-aminobutyric acid receptor subunit gamma-13003
Gamma-aminobutyric acid receptor subunit alpha-23003
Sodium-dependent noradrenaline transporter 0202
Endothelin-1 receptor1001
Gamma-aminobutyric acid receptor subunit alpha-43003
Gamma-aminobutyric acid receptor subunit gamma-33003
Gamma-aminobutyric acid receptor subunit alpha-63003
Histamine H2 receptor1001
Gamma-aminobutyric acid receptor subunit alpha-13003
Gamma-aminobutyric acid receptor subunit beta-33003
Gamma-aminobutyric acid receptor subunit beta-23003
Sodium-dependent dopamine transporter 0202
GABA theta subunit3003
Inositol hexakisphosphate kinase 11001
ATPase family AAA domain-containing protein 52002
Gamma-aminobutyric acid receptor subunit epsilon3003
Protein-arginine deiminase type-40101
cytochrome P450 2C9, partial1001
Chain A, Inosine-5'-Monophosphate Dehydrogenase 20101
Chain A, HADH2 protein1001
Chain B, HADH2 protein1001
Chain A, 2-oxoglutarate Oxygenase2002
SMAD family member 21001
SMAD family member 31001
aldehyde dehydrogenase 1 family, member A13003
peroxisome proliferator activated receptor gamma3003
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 11001
lethal factor (plasmid)1001
UDP-glucuronosyltransferase 1A90001
Inosine-5'-monophosphate dehydrogenase 20202
Glutamate receptor 10101
Glutamate receptor 30101
Glutamate receptor 40101
Inosine-5'-monophosphate dehydrogenase 1 0202
UDP-glucuronosyltransferase 1A1 0001
Sodium-dependent serotonin transporter0101
Peroxisome proliferator-activated receptor gamma0011
Alpha-synuclein2002
TAR DNA-binding protein 433003
Inosine-5'-monophosphate dehydrogenase0102
UDP-glucuronosyltransferase 1A70001
UDP-glucuronosyltransferase 1A100001
UDP-glucuronosyltransferase 1A80001
Sialidase-40101
Sialidase-10101
Sialidase-30101
Sialidase-20101
GALC protein1001
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)1001
thyroid stimulating hormone receptor1001
beta-2 adrenergic receptor1001
lysosomal alpha-glucosidase preproprotein1001
mu-type opioid receptor isoform MOR-10011
chromobox protein homolog 12002
Vpr2002
5-hydroxytryptamine receptor 2A0011
Neuronal acetylcholine receptor subunit alpha-41001
Neuronal acetylcholine receptor subunit beta-21001
NS5 0011
interleukin 81001
thyroid stimulating hormone receptor1001
alpha-galactosidase1001
glycogen synthase kinase-3 beta isoform 10011
Voltage-dependent L-type calcium channel subunit alpha-1F0101
Rap guanine nucleotide exchange factor 31001
Polymerase basic protein 20011
RNA-directed RNA polymerase catalytic subunit0011
Polymerase acidic protein0011
Adenosine receptor A30101
Adenosine receptor A2a0101
Adenosine receptor A10101
Nuclear receptor ROR-gamma1001
Voltage-dependent L-type calcium channel subunit alpha-1D 0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Adenosine receptor A10101
Genome polyprotein0011
Chain A, Uracil-DNA Glycosylase0101
Protein cereblon0202
Nrf21001
WRN1001
GLS protein1001
Microtubule-associated protein tau1001
Smad31001
regulator of G-protein signaling 41001
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
transcriptional regulator ERG isoform 31001
importin subunit beta-1 isoform 11001
heat shock protein HSP 90-alpha isoform 20001
snurportin-11001
peptidyl-prolyl cis-trans isomerase NIMA-interacting 11001
GTP-binding nuclear protein Ran isoform 11001
DNA dC->dU-editing enzyme APOBEC-3G isoform 11001
endoribonuclease toxin MazF0011
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform0112
Serine/threonine-protein kinase PLK40101
Myosin light chain kinase, smooth muscle0101
Metabotropic glutamate receptor 10101
Phosphatidylinositol 3-kinase regulatory subunit alpha0101
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform0213
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform0112
Phosphatidylinositol 4-kinase alpha0101
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0112
Serine/threonine-protein kinase PLK10202
Guanine nucleotide-binding protein G1001
DNA-dependent protein kinase catalytic subunit0101
Inositol monophosphatase 11001
Myosin light chain kinase, smooth muscle0101
Phosphoinositide 3-kinase regulatory subunit 50101
Phosphatidylinositol 4-kinase type 2-alpha0101
Serine/threonine-protein kinase PLK30202
Serine/threonine-protein kinase PLK20101
Phosphatidylinositol 4-kinase beta0101
heat shock protein 90, putative0001
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]