Page last updated: 2024-09-27

Perineural Cyst

Perineurial cysts commonly found in the SACRAL REGION. They arise from the PERINEURIUM membrane within the SPINAL NERVE ROOTS. The distinctive feature of the cysts is the presence of spinal nerve root fibers within the cyst wall, or the cyst cavity itself.

Synonyms(9)

Synonym
Perineural Cyst
Sacral Tarlov Cysts
Sacral Perineural Cysts
Perineurial Cysts
Perineural Cysts
Sacral Perineural Cyst
Tarlov Cysts
Tarlov Cyst
Perineurial Cyst

Research Excerpts

Overview

ExcerptReference
"Symptomatic sacral perineural cysts are a common cause of chronic pain."( Hao, J; Hu, Z; Jiang, W; Qiu, Q; Shui, W; Zhang, X, 2015)
"Sacral perineural cysts are also known as Tarlov cysts."( Bui, C; Le, K; Mansberg, R; Vamadevan, S, 2017)
"Symptomatic Tarlov cysts are a common cause of chronic pain."( Hao, J; Hu, Z; Jiang, W, 2017)

Research

Studies (9)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's0 (0.00)12.5806
2000's2 (22.22)18.1394
2010's6 (66.67)28.8240
2020's1 (11.11)9.53
DrugIndicatedRelationship StrengthStudiesTrials
lidocaine0low10
methylmethacrylate0low10
technetium tc 99m pentetate0low10
ropivacaine0low10
fibrin0low20
gadolinium dtpa0low10

Protein Targets (53)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE1001
Chain A, Beta-lactamase1001
thioredoxin reductase1001
RAR-related orphan receptor gamma1001
GLS protein1001
TDP1 protein1001
Microtubule-associated protein tau1001
AR protein1001
aldehyde dehydrogenase 1 family, member A12002
vitamin D (1,25- dihydroxyvitamin D3) receptor1001
IDH11001
euchromatic histone-lysine N-methyltransferase 21001
chromobox protein homolog 11001
mitogen-activated protein kinase 11001
flap endonuclease 11001
geminin1001
cytochrome P450 3A4 isoform 11001
muscarinic acetylcholine receptor M11001
lamin isoform A-delta102002
Gamma-aminobutyric acid receptor subunit pi1001
Potassium channel subfamily K member 30202
ATP-binding cassette sub-family C member 30101
Multidrug resistance-associated protein 40101
Potassium channel subfamily K member 20101
Bile salt export pump0202
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0101
Gamma-aminobutyric acid receptor subunit beta-11001
Gamma-aminobutyric acid receptor subunit delta1001
Gamma-aminobutyric acid receptor subunit gamma-21001
Gamma-aminobutyric acid receptor subunit alpha-51001
Gamma-aminobutyric acid receptor subunit alpha-31001
Potassium voltage-gated channel subfamily A member 50101
Gamma-aminobutyric acid receptor subunit gamma-11001
Gamma-aminobutyric acid receptor subunit alpha-21001
Gamma-aminobutyric acid receptor subunit alpha-41001
Gamma-aminobutyric acid receptor subunit gamma-31001
Gamma-aminobutyric acid receptor subunit alpha-61001
Sodium channel protein type 4 subunit alpha0101
Gamma-aminobutyric acid receptor subunit alpha-11001
Gamma-aminobutyric acid receptor subunit beta-31001
Gamma-aminobutyric acid receptor subunit beta-21001
Potassium voltage-gated channel subfamily H member 20101
Sodium channel protein type 5 subunit alpha0101
Sodium channel protein type 9 subunit alpha0101
Potassium voltage-gated channel subfamily D member 20101
Potassium channel subfamily K member 180101
GABA theta subunit1001
Canalicular multispecific organic anion transporter 10101
Multidrug and toxin extrusion protein 10101
Gamma-aminobutyric acid receptor subunit epsilon1001
Sodium channel protein type 3 subunit alpha0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]