Amnesic Shellfish Poisoning

Poisoning from toxins present in bivalve mollusks that have been ingested. Four distinct types of shellfish poisoning are recognized based on the toxin involved.

Synonym
Shellfish Poisoning
Diarrhetic Shellfish Poisoning
Neurotoxic Shellfish Poisoning
Amnesic Shellfish Poisoning
Paralytic Shellfish Poisoning

Excerpt	Reference
"Paralytic shellfish poisoning is differentiated from other forms of poisioning from marine animals."	( Mills, CG; Popei, K; Rhodes, FA, 1975)
"Paralytic shellfish poisoning is caused by the ingestion of shellfish meat rendered toxic by exposure to a high level of toxic dinoflagellates during the phenomenon of "red tide"."	( Lee, EJ; Tan, CT, 1986)
"Paralytic shellfish poisoning is one of the most severe forms of food poisoning."	( Botana, LM; Garcia Cabado, A; Louzao, MC; Rodriguez Vieytes, M; Vieites Baptista De Sousa, JM, 2003)
"Paralytic shellfish poisoning is a toxic syndrome described in humans following the ingestion of seafood contaminated with saxitoxin and/or its derivatives."	( Botana, LM; Campbell, K; Elliott, CT; Fraga, M; Kawatsu, K; Louzao, MC; Vieytes, MR; Vilariño, N, 2012)
"Diarrhetic shellfish poisoning is a gastrointestinal illness caused by consumption of bivalves contaminated with dinophysistoxins."	( Borchert, J; Duchin, JS; Lloyd, JK; Quintana, HF; Robertson, A, 2013)
"Paralytic shellfish poisoning is caused by a group of paralytic shellfish toxins that are produced by dinoflagellates."	( Eangoor, P; Indapurkar, AS; Knaack, JS; Vakkalanka, M; Yeh, JS, 2017)
"Paralytic shellfish poisoning is caused by saxitoxin and its analogues."	( Jo, H; Kang, GJ; Kim, SH; Shin, C, 2018)
"Paralytic shellfish poisoning is a worldwide problem induced by shellfish contaminated with paralytic shellfish toxins."	( Boundy, MJ; Broadhurst, RB; Finch, SC; Harwood, DT; Munday, JS; Somchit, C; Sprosen, JM; Webb, NG, 2023)

Excerpt	Reference
"Outbreaks of paralytic shellfish poisoning have occurred worldwide."	( Gessner, BD; Middaugh, JP, 1995)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	28 (6.67)	23.3326
1990's	54 (12.86)	12.5806
2000's	60 (14.29)	18.1394
2010's	206 (49.05)	28.8240
2020's	72 (17.14)	9.53

Drug	Relationship Strength	Studies
acetic acid	low	1
ammonium hydroxide	low	1
carbamates	low	3
histamine	low	1
iodine	low	1
methanol	low	2
nitrates	low	1
putrescine	low	1
sulfur dioxide	low	1
uracil	low	4
caffeine	low	1
cyproheptadine	low	1
erythrosine	low	2
furosemide	low	1
kynurenic acid	low	1
tyramine	low	1
tert-butylhydroperoxide	low	1
boric acid	low	1
acrolein	low	1
2-methylpentane	low	1
hexachlorobenzene	low	1
oxazoles	low	1
thiazoles	low	1
kainic acid	low	63
acetylcysteine	low	1
4-aminothiophenol	low	1
sodium hydroxide	low	1
manganese dioxide	low	1
octachloronaphthalene	low	9
mercury	low	2
silver	low	2
cadmium	low	1
gold	low	1
ozone	low	1
fenitrothion	low	1
dobutamine	low	1
tetramethylenedisulfotetramine	low	3
thiazolyl blue	low	1
4-methylumbelliferyl phosphate	low	1
metaperiodate	low	1
geographutoxin i	low	4
3,6-fluorescein diphosphate	low	1
attophos	low	1
benzofurans	low	1
anatoxin a	low	2
ouabain	low	1
casein hydrolysate	low	1
monensin	low	1
neriifolin	low	1
cyanoginosin lr	low	2
cinnamaldehyde	low	1
amygdalin	low	1
curcumin	low	1
ranitidine	low	1
surugatoxin	low	1
safingol	low	1
ovalbumin	low	1
mtt formazan	low	1
sphingosine	low	1
hymecromone	low	1
domoic acid	low	61
ciguatoxins	low	8
calyculin a	low	1
cesium	low	1
mevinphos	low	1
silicon	low	1
phosphorus	low	1
tetrodotoxin	low	28
pectenotoxin 2	low	6
pectenotoxin 1	low	1
formazans	low	1
oregon green 514	low	1
palytoxin	low	4
veratridine	low	2
s-tetradecanoyl-coenzyme a	low	1
yessotoxin	low	9
nodularin	low	1
gramicidin a	low	1
neuropeptide y	low	1
oligonucleotides	low	1
chlorophyll a	low	2
dinophysistoxin 1	low	27
decarbamylsaxitoxin	low	2
azaspiracid	low	20
chitosan	low	2
sodium glutamate	low	1
neosurugatoxin	low	1
atorvastatin calcium	low	2
microcystin	low	3
clay	low	2
brevetoxin	low	16
saxitoxin	low	140
okadaic acid	low	99
caseins	low	1
benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone	low	1
peptide yy	low	1
dinophysistoxin 2	low	22
spirolide a	low	2
gonyautoxin ii	low	3
t-2 toxin	low	1
gymnodimine	low	3
prosurugatoxin	low	1
exudates	low	5
ovatoxin-a	low	1
pinnatoxin f	low	1
pinnatoxin e	low	1

Protein Targets (687)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
retinoic acid nuclear receptor alpha variant 1	12	0	0	12
retinoid X nuclear receptor alpha	12	0	0	12
estrogen-related nuclear receptor alpha	13	0	0	13
pregnane X nuclear receptor	9	0	0	9
Cytochrome P450 2D6	0	0	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	2	0	3
Tyrosine-protein phosphatase non-receptor type 11	0	0	0	1
estrogen nuclear receptor alpha	19	0	0	19
Free fatty acid receptor 3	0	0	1	1
Free fatty acid receptor 2	0	1	1	2
Tyrosine-protein kinase Lck	0	1	1	2
Tyrosine-protein kinase Fyn	0	1	1	2
Fibrinogen C domain-containing protein 1	0	1	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	6	0	0	6
Chain A, 2-oxoglutarate Oxygenase	5	0	0	5
Chain A, ATP-DEPENDENT DNA HELICASE Q1	2	0	0	2
acetylcholinesterase	11	0	0	11
dopamine D1 receptor	3	0	0	3
15-lipoxygenase, partial	2	0	0	2
pregnane X receptor	2	0	0	2
phosphopantetheinyl transferase	11	0	0	11
RAR-related orphan receptor gamma	11	0	0	11
USP1 protein, partial	5	0	0	5
NFKB1 protein, partial	3	0	0	3
Microtubule-associated protein tau	3	0	0	3
Thrombopoietin	1	0	0	1
AR protein	18	0	0	18
regulator of G-protein signaling 4	8	0	0	8
glucocorticoid receptor [Homo sapiens]	12	0	0	12
farnesoid X nuclear receptor	10	0	0	10
vitamin D (1,25- dihydroxyvitamin D3) receptor	9	0	0	9
arylsulfatase A	2	0	0	2
euchromatic histone-lysine N-methyltransferase 2	13	0	0	13
Bloom syndrome protein isoform 1	4	0	0	4
D(1A) dopamine receptor	3	0	0	3
thyroid hormone receptor beta isoform a	6	0	0	6
thyroid hormone receptor beta isoform 2	12	0	0	12
heat shock protein beta-1	7	0	0	7
flap endonuclease 1	3	0	0	3
geminin	15	0	0	15
peripheral myelin protein 22	6	0	0	6
survival motor neuron protein isoform d	4	0	0	4
muscarinic acetylcholine receptor M1	6	0	0	6
Histone deacetylase 3	0	2	0	2
Solute carrier family 22 member 6	0	2	0	2
Histone deacetylase 4	0	2	0	2
Guanine nucleotide-binding protein G	2	0	0	2
Histone deacetylase 1	0	3	0	3
Histone deacetylase 7	0	2	0	2
Histone deacetylase 2	0	3	0	3
Polyamine deacetylase HDAC10	0	2	0	2
Histone deacetylase 11	0	2	0	2
Ataxin-2	7	0	0	7
Histone deacetylase 8	0	3	0	3
Histone deacetylase 6	0	2	0	2
Histone deacetylase 9	0	2	0	2
Histone deacetylase 5	0	2	0	2
ATP-dependent phosphofructokinase	7	0	0	7
aldehyde dehydrogenase 1 family, member A1	11	0	0	11
thyroid stimulating hormone receptor	7	0	0	7
peroxisome proliferator activated receptor gamma	8	0	0	8
nuclear factor erythroid 2-related factor 2 isoform 1	13	0	0	13
Transient receptor potential cation channel subfamily A member 1	0	0	2	3
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	5	0	0	5
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain B, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, tRNA (guanine-N(1)-)-methyltransferase	0	0	1	1
Chain A, Uncharacterized protein MJ0883	0	0	1	1
signal transducer and activator of transcription 6, interleukin-4 induced	1	0	0	1
NPYLR7B	0	0	1	1
IDH1	6	0	0	6
Histone H2A.x	6	0	0	6
glycogen synthase kinase-3 beta isoform 1	0	0	1	1
mitogen-activated protein kinase 1	5	0	0	5
nuclear receptor ROR-gamma isoform 1	5	0	0	5
high affinity choline transporter 1 isoform a	0	1	0	1
Sodium/nucleoside cotransporter 1	0	2	0	2
Calcium dependent protein kinase	0	1	0	1
Mitogen-activated protein kinase kinase kinase 7	0	0	1	1
Sodium/nucleoside cotransporter 2	0	2	0	2
Voltage-dependent calcium channel gamma-2 subunit	10	0	0	10
Rap guanine nucleotide exchange factor 3	2	0	0	2
Purine nucleoside phosphorylase	0	1	0	1
Epidermal growth factor receptor	0	2	0	2
Phosphoglycerate kinase 1	0	1	0	1
Adenosine deaminase	0	0	0	1
Avidin	0	0	1	1
Adenosine deaminase	0	0	0	1
Glyceraldehyde-3-phosphate dehydrogenase	0	2	0	2
Receptor tyrosine-protein kinase erbB-2	0	1	0	1
Insulin receptor	0	0	0	1
Phosphoglycerate kinase 2	0	1	0	1
Heat shock protein HSP 90-alpha	0	1	1	2
Platelet-derived growth factor receptor beta	0	0	0	1
Adenosine receptor A3	0	3	2	6
Heat shock 70 kDa protein 1A	0	1	0	1
Heat shock cognate 71 kDa protein	0	0	1	1
Fibroblast growth factor receptor 1	0	0	0	1
Inosine-5'-monophosphate dehydrogenase 2	0	1	0	1
Endoplasmin	0	1	1	2
Glutamate receptor 2	10	3	1	15
Inosine-5'-monophosphate dehydrogenase 1	0	1	0	1
Fibroblast growth factor receptor 2	0	0	0	1
Fibroblast growth factor receptor 4	0	0	0	1
Fibroblast growth factor receptor 3	0	0	0	1
Streptavidin	0	0	1	1
Adenosylhomocysteinase	0	0	0	1
Adenosine receptor A1	0	3	1	6
Adenosine receptor A3	0	2	0	2
Adenosine receptor A2a	0	3	3	8
Adenosine receptor A2b	0	1	1	4
Adenosine receptor A2b	0	3	1	5
Adenylate kinase 2, mitochondrial	0	1	0	1
Adenosine receptor A1	0	3	3	9
Adenosine receptor A2a	0	3	1	7
Adenylate kinase isoenzyme 1	0	1	0	1
Phosphatidylinositol 4-kinase alpha	0	2	0	3
Adenosine receptor A1	0	2	1	3
Adenosine kinase	0	0	0	1
Adenosine deaminase	0	0	0	1
Equilibrative nucleoside transporter 2	0	2	0	2
Phosphatidylinositol 4-kinase type 2-beta	0	2	0	3
Histone-lysine N-methyltransferase, H3 lysine-79 specific	0	1	0	1
Equilibrative nucleoside transporter 1	0	2	0	2
Phosphatidylinositol 4-kinase type 2-alpha	0	2	0	3
Solute carrier family 28 member 3	0	2	0	2
Adenosine kinase	0	1	0	2
Phosphatidylinositol 4-kinase beta	0	2	0	3
5-methylthioadenosine/S-adenosylhomocysteine deaminase	0	0	0	1
Adenosine transporter 1	0	0	0	1
Acetylcholine receptor subunit alpha	0	1	0	1
Acetylcholine receptor subunit beta	0	1	0	1
Acetylcholine receptor subunit gamma	0	1	0	1
Acetylcholine receptor subunit delta	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-3	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-2	0	1	1	2
Neuronal acetylcholine receptor subunit beta-2	0	2	1	3
Neuronal acetylcholine receptor subunit beta-3	0	1	1	2
Neuronal acetylcholine receptor subunit beta-4	0	2	1	3
Neuronal acetylcholine receptor subunit beta-2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-5	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-6	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-9	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-10	0	1	1	2
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	3	0	0	3
lamin isoform A-delta10	10	0	0	10
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Chain A, Glycogen Phosphorylase	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Chitinase	0	1	0	1
GLS protein	9	0	0	9
GLI family zinc finger 3	10	0	0	10
nuclear receptor subfamily 1, group I, member 3	8	0	0	8
thyroid stimulating hormone receptor	7	0	0	7
v-jun sarcoma virus 17 oncogene homolog (avian)	7	0	0	7
atrial natriuretic peptide receptor 1 precursor	1	0	0	1
chromobox protein homolog 1	7	0	0	7
DNA polymerase beta	3	0	0	3
DNA polymerase kappa isoform 1	7	0	0	7
lethal factor (plasmid)	4	0	0	4
ATP-binding cassette sub-family C member 3	0	2	0	2
Multidrug resistance-associated protein 4	0	2	0	2
Potassium channel subfamily K member 2	0	0	1	1
Bile salt export pump	0	6	0	6
Glycogen phosphorylase, muscle form	0	1	0	1
Renin	0	1	0	1
Carbonic anhydrase 1	0	7	0	9
Carbonic anhydrase 2	0	7	0	10
Cholinesterase	0	2	0	2
Glycogen phosphorylase, liver form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Replicase polyprotein 1ab	0	2	1	3
Replicase polyprotein 1ab	0	3	1	4
Amine oxidase [flavin-containing] A	0	3	0	4
Acetylcholinesterase	0	2	0	2
Amine oxidase [flavin-containing] B	0	5	0	6
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Vasopressin V2 receptor	0	0	0	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Adenosine receptor A2a	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	1	0	1
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Adenylate cyclase type 1	0	0	0	1
Chitotriosidase-1	0	1	0	1
Serine-protein kinase ATM	0	1	0	1
Serine/threonine-protein kinase ATR	0	1	0	1
Adenosine receptor A2b	0	1	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	1	2	3
Endochitinase B1	0	1	0	1
Muscarinic acetylcholine receptor	0	0	0	1
Canalicular multispecific organic anion transporter 1	0	2	0	2
Phosphodiesterase	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	3	0	3
Guanine deaminase	0	1	0	1
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit	0	2	0	2
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B	0	2	0	2
Luciferase	6	0	0	6
interleukin 8	3	0	0	3
67.9K protein	2	0	0	2
shiga toxin 1 variant A subunit	1	0	0	1
shiga toxin 1 B subunit	1	0	0	1
peroxisome proliferator-activated receptor delta	6	0	0	6
aryl hydrocarbon receptor	8	0	0	8
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	10	0	0	10
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	2	0	0	2
Polyphenol oxidase 2	0	1	0	2
Cellular tumor antigen p53	13	0	0	13
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	2
Cell division protein FtsZ	0	1	0	3
Prostaglandin G/H synthase 2	0	2	0	2
Nuclear receptor ROR-gamma	2	0	0	2
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Chain A, Breast cancer type 1 susceptibility protein	1	0	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	3	0	0	3
Chain A, HADH2 protein	5	0	0	5
Chain B, HADH2 protein	5	0	0	5
Chain A, Ferritin light chain	4	0	0	4
Chain A, Cruzipain	2	0	0	2
Nrf2	1	0	0	1
thioredoxin reductase	8	0	0	8
hypoxia-inducible factor 1 alpha subunit	6	0	0	6
SMAD family member 2	6	0	0	6
ATAD5 protein, partial	7	0	0	7
SMAD family member 3	6	0	0	6
TDP1 protein	12	0	0	12
alkaline phosphatase, intestinal	0	1	0	1
thioredoxin glutathione reductase	3	0	0	3
Smad3	2	0	0	2
apical membrane antigen 1, AMA1	5	0	0	5
caspase 7, apoptosis-related cysteine protease	3	0	0	3
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	2	0	0	2
PINK1	1	0	0	1
estrogen receptor 2 (ER beta)	8	0	0	8
progesterone receptor	7	0	0	7
EWS/FLI fusion protein	5	0	0	6
glucocerebrosidase	3	0	0	3
Parkin	2	0	0	2
bromodomain adjacent to zinc finger domain 2B	4	0	0	4
toll-like receptor 9	0	1	0	1
caspase-3	3	0	0	3
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	2	0	0	2
TPA: protein transporter TIM10	0	1	0	1
activating transcription factor 6	9	0	0	9
thyrotropin-releasing hormone receptor	3	0	0	3
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	7	0	0	7
lysosomal alpha-glucosidase preproprotein	3	0	0	3
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein	0	1	0	1
hemoglobin subunit beta	1	0	0	1
cellular tumor antigen p53 isoform a	2	0	0	2
polyunsaturated fatty acid lipoxygenase ALOX12	1	0	0	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	4	0	0	4
perilipin-5	0	1	0	1
vitamin D3 receptor isoform VDRA	5	0	0	5
intestinal alkaline phosphatase precursor	0	1	0	1
perilipin-1	0	1	0	1
potassium voltage-gated channel subfamily H member 2 isoform d	5	0	0	5
transcriptional regulator ERG isoform 3	1	0	0	1
huntingtin isoform 2	3	0	0	3
importin subunit beta-1 isoform 1	4	0	0	4
pyruvate kinase PKM isoform a	1	0	0	1
nuclear factor NF-kappa-B p105 subunit isoform 1	1	0	0	1
snurportin-1	4	0	0	4
histone-lysine N-methyltransferase 2A isoform 2 precursor	2	0	0	2
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	2	0	0	2
tumor susceptibility gene 101 protein	1	0	0	1
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
DNA polymerase iota isoform a (long)	5	0	0	5
urokinase-type plasminogen activator precursor	2	0	0	2
plasminogen precursor	2	0	0	2
urokinase plasminogen activator surface receptor precursor	2	0	0	2
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	1	0	1
cytochrome P450 3A4 isoform 1	1	0	0	1
muscleblind-like protein 1 isoform 1	1	0	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	0	0	1
alkaline phosphatase, germ cell type preproprotein	0	1	0	1
caspase-1 isoform alpha precursor	2	0	0	2
hypothetical protein SA1422	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3F isoform a	1	0	0	1
neuropeptide S receptor isoform A	1	0	0	1
Gamma-aminobutyric acid receptor subunit pi	1	0	0	1
Prostaglandin E synthase	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	2	0	0	2
Acetylcholinesterase	0	2	0	2
Lysine-specific histone demethylase 1A	0	1	0	1
D-amino-acid oxidase	0	1	0	1
Phospholipase A2	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	2	0	2
Amyloid-beta precursor protein	0	1	0	2
Integrin beta-3	1	0	0	1
Neuronal proto-oncogene tyrosine-protein kinase Src	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	2
Heme oxygenase 1	0	1	0	1
Integrin alpha-IIb	1	0	0	1
Glutathione S-transferase P	0	1	0	1
60 kDa chaperonin	0	1	0	1
Microtubule-associated protein tau	0	1	0	2
60 kDa heat shock protein, mitochondrial	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	0	1	0	1
Tissue factor	0	1	0	1
Tyrosinase	0	1	0	1
Aminopeptidase N	0	1	0	1
Aminopeptidase N	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	1	0	0	1
Alpha-1B adrenergic receptor	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	0	2	0	2
Glycogen synthase kinase-3 beta	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	1	0	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	1	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	1	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	1	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	1	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	1	0	0	1
Heme oxygenase 2	0	1	0	1
Alpha-1D adrenergic receptor	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Proteasome subunit beta type-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	1	0	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	1	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	1	0	0	1
17-beta-hydroxysteroid dehydrogenase type 2	0	1	0	1
Alpha-synuclein	1	1	1	3
Alpha-1A adrenergic receptor	0	1	0	1
Histamine H2 receptor	3	0	1	4
Glycogen synthase kinase-3 beta	0	1	0	1
Caspase-7	2	0	0	2
Beta-secretase 1	0	1	1	2
10 kDa heat shock protein, mitochondrial	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	1	0	0	1
Gamma-aminobutyric acid receptor subunit beta-3	1	0	0	1
Gamma-aminobutyric acid receptor subunit beta-2	1	0	0	1
Cholinesterase	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Lactoylglutathione lyase	0	1	0	1
Histone acetyltransferase p300	0	1	0	1
TAR DNA-binding protein 43	3	0	0	3
Serine/threonine-protein kinase PAK 1	0	1	0	1
5-hydroxytryptamine receptor 4	0	0	1	1
Sodium/bile acid cotransporter	0	1	1	2
Nuclear factor erythroid 2-related factor 2	0	0	1	1
Thiosulfate sulfurtransferase	0	1	0	1
Thioredoxin reductase 1, cytoplasmic	0	1	0	1
60 kDa chaperonin	0	1	0	1
10 kDa chaperonin	0	1	0	1
Thioredoxin reductase 3	0	1	0	1
Sortase A	0	1	0	1
GABA theta subunit	1	0	0	1
CREB-binding protein	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3	0	2	0	2
Cysteine protease	0	1	0	1
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
ATPase family AAA domain-containing protein 5	4	0	0	4
Gamma-aminobutyric acid receptor subunit epsilon	1	0	0	1
Thioredoxin reductase 2, mitochondrial	0	1	0	1
CDGSH iron-sulfur domain-containing protein 1	0	4	0	4
Lymphocyte antigen 96	0	0	1	1
Beta lactamase (plasmid)	0	1	0	1
Protein phosphatase 1A	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	0	0	2
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform	0	1	0	1
Solute carrier organic anion transporter family member 1B3	0	0	0	1
Solute carrier organic anion transporter family member 1B1	0	0	0	1
Fumarate hydratase	3	0	0	3
PPM1D protein	2	0	0	2
cytochrome P450 2D6	6	0	0	6
polyprotein	3	0	0	3
cytochrome P450 2D6 isoform 1	1	0	0	1
cytochrome P450 2C19 precursor	4	0	0	4
atrial natriuretic peptide receptor 2 precursor	1	0	0	1
serine/threonine-protein kinase mTOR isoform 1	2	0	0	2
histone acetyltransferase KAT2A isoform 1	5	0	0	5
chaperonin GroEL	1	0	0	1
Sodium-dependent noradrenaline transporter	0	1	0	1
5-hydroxytryptamine receptor 4	0	2	0	2
Interferon beta	4	0	0	4
Aldo-keto reductase family 1 member B1	0	5	0	5
Muscarinic acetylcholine receptor M2	0	2	0	2
Muscarinic acetylcholine receptor M4	0	2	0	2
Muscarinic acetylcholine receptor M1	0	2	0	2
Muscarinic acetylcholine receptor M3	0	1	0	1
Muscarinic acetylcholine receptor M4	0	1	0	1
5-hydroxytryptamine receptor 2C	0	1	1	2
Muscarinic acetylcholine receptor M5	0	1	0	1
Muscarinic acetylcholine receptor M5	0	2	0	2
Alpha-2A adrenergic receptor	0	2	0	2
Muscarinic acetylcholine receptor M2	0	1	0	1
Glycogen phosphorylase, brain form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Muscarinic acetylcholine receptor M1	0	2	0	2
Angiotensin-converting enzyme	0	2	0	2
D(2) dopamine receptor	0	3	0	3
5-hydroxytryptamine receptor 2A	0	2	1	3
Alpha-2B adrenergic receptor	0	4	0	4
Alpha-2C adrenergic receptor	0	2	0	2
D	0	1	0	1
D(3) dopamine receptor	0	1	0	1
5-hydroxytryptamine receptor 1A	0	2	1	3
Muscarinic acetylcholine receptor M3	0	2	0	2
Endothelin receptor type B	0	1	0	1
D(1A) dopamine receptor	0	3	0	4
UDP-glucuronosyltransferase 1A4	0	0	0	1
Sodium-dependent noradrenaline transporter	0	4	0	4
Endothelin receptor type B	0	1	0	1
Histamine H2 receptor	0	3	2	5
Alpha-1D adrenergic receptor	0	4	0	4
D(1B) dopamine receptor	0	1	0	1
5-hydroxytryptamine receptor 2A	0	2	0	2
5-hydroxytryptamine receptor 2C	0	2	0	2
5-hydroxytryptamine receptor 1B	0	2	1	3
D(4) dopamine receptor	0	1	0	1
5-hydroxytryptamine receptor 2B	0	1	1	2
Sodium-dependent serotonin transporter	0	3	0	3
5-hydroxytryptamine receptor 7	0	1	1	2
5-hydroxytryptamine receptor 2C	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
Histamine H1 receptor	0	4	3	7
D(3) dopamine receptor	0	4	0	4
UDP-glucuronosyltransferase 1A3	0	0	0	1
5-hydroxytryptamine receptor 2B	0	2	0	2
5-hydroxytryptamine receptor 6	0	2	0	2
Spike glycoprotein	3	0	0	3
D(2) dopamine receptor	0	1	0	1
D(2) dopamine receptor	0	2	0	2
Potassium voltage-gated channel subfamily H member 2	0	3	0	3
Sodium-dependent serotonin transporter	0	1	0	1
Nuclear receptor subfamily 3 group C member 3	0	2	0	2
Histone-lysine N-methyltransferase SETD7	0	2	0	2
Transporter	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	2	0	2
Sodium channel protein type 9 subunit alpha	0	3	0	3
Chain A, Beta-lactamase	5	0	0	5
glp-1 receptor, partial	2	0	0	2
nuclear factor erythroid 2-related factor 2 isoform 2	1	0	0	1
Vpr	1	0	0	1
Glutathione S-transferase omega-1	0	1	0	1
GALC protein	3	0	0	3
cytochrome P450 family 3 subfamily A polypeptide 4	5	0	0	5
mu-type opioid receptor isoform MOR-1	0	0	1	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Solute carrier family 22 member 1	0	1	0	3
Carbonic anhydrase 12	0	3	0	5
Carbonic anhydrase 3	0	2	0	3
Beta-2 adrenergic receptor	0	2	0	2
Beta-1 adrenergic receptor	0	2	0	2
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
POU domain, class 2, transcription factor 1	0	0	0	1
Carbonic anhydrase 4	0	4	0	6
Carbonic anhydrase 6	0	2	0	4
Carbonic anhydrase 5A, mitochondrial	0	3	0	5
Carbonic anhydrase 7	0	2	0	4
Sodium-dependent dopamine transporter	0	2	0	2
Carbonic anhydrase 9	0	4	0	6
Carbonic anhydrase 13	0	1	0	2
Sigma non-opioid intracellular receptor 1	0	2	0	2
Carbonic anhydrase 15	0	2	0	3
Carbonic anhydrase 14	0	2	0	4
Carbonic anhydrase 5B, mitochondrial	0	2	0	4
Genome polyprotein	0	1	1	2
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
hypothetical protein, conserved	1	0	0	1
G	2	0	0	2
ubiquitin carboxyl-terminal hydrolase 2 isoform a	1	0	0	1
eyes absent homolog 2 isoform a	1	0	0	1
lethal(3)malignant brain tumor-like protein 1 isoform I	2	0	0	2
relaxin receptor 1 isoform 1	1	0	0	1
HLA class I histocompatibility antigen, B alpha chain	2	0	0	2
Flavin reductase (NADPH)	0	0	1	1
Inositol hexakisphosphate kinase 1	2	0	0	2
cytochrome P450 2C9, partial	2	0	0	2
large T antigen	0	1	0	1
Bile salt export pump	0	1	0	1
Albumin	0	1	0	1
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Cytochrome P450 2C9	0	1	0	1
Serum paraoxonase/arylesterase 1	0	1	0	1
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Cytochrome P450 2J2	0	1	0	1
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Holo-[acyl-carrier-protein] synthase	0	1	0	1
Solute carrier organic anion transporter family member 2A1	0	1	0	1
Multidrug and toxin extrusion protein 1	0	1	0	1
Carbonic anhydrase 13	0	1	0	3
G-protein coupled receptor 35	0	3	2	5
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Protein (female-specific Histamine Binding Protein 2)	0	0	1	1
aryl hydrocarbon receptor nuclear translocator	0	0	0	1
transforming acidic coiled-coil-containing protein 3	0	0	0	1
Solute carrier family 22 member 2	0	0	0	1
Solute carrier family 22 member 3	0	1	0	2
Plasma kallikrein	0	0	0	1
Macrophage migration inhibitory factor	0	2	0	2
5-hydroxytryptamine receptor 1D	0	0	0	1
Histamine H1 receptor	0	1	2	3
Histamine H1 receptor	0	2	1	3
Metabotropic glutamate receptor 5	0	1	1	2
Glutamate receptor ionotropic, NMDA 1	0	4	1	7
Carbonic anhydrase	0	1	0	2
Carbonic anhydrase	0	0	0	2
Histamine H3 receptor	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	3	1	6
Glutamate receptor ionotropic, NMDA 2B	0	3	1	6
Glutamate receptor ionotropic, NMDA 2C	0	3	1	6
Histamine N-methyltransferase	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	1	0	1
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase-like protein, putative	0	0	0	1
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	0	0	2
Glutamate receptor ionotropic, NMDA 2D	0	3	1	6
Solute carrier family 22 member 1	0	1	0	2
Carbonic anhydrase	0	0	0	2
Equilibrative nucleoside transporter 4	0	0	0	1
Glutamate receptor ionotropic, NMDA 3B	0	3	1	6
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	0	1
Carbonic anhydrase 4	0	0	0	1
Histamine H4 receptor	0	2	2	4
Histamine H3 receptor	0	1	0	1
Carboxylic ester hydrolase	0	0	0	1
Solute carrier family 22 member 2	0	1	0	2
Glutamate receptor ionotropic, NMDA 3A	0	3	1	6
Histamine H3 receptor	0	1	2	3
alpha-galactosidase	3	0	0	3
cytochrome P450 2C9 precursor	1	0	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Nuclear factor NF-kappa-B p105 subunit	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	1	0	1
Genome polyprotein	0	1	0	1
Testosterone 17-beta-dehydrogenase 3	0	1	0	1
Small conductance calcium-activated potassium channel protein 3	0	1	0	1
Sorbitol dehydrogenase	0	1	0	1
Induced myeloid leukemia cell differentiation protein Mcl-1	0	2	0	2
Oleandomycin glycosyltransferase	0	0	0	1
histone deacetylase 9 isoform 3	1	0	0	1
Chain A, Glutamate receptor 2	0	0	1	1
Chain A, Glutamate receptor 2	0	0	1	1
Chain C, Glutamate receptor 2	0	0	1	1
endonuclease IV	2	0	0	2
Metabotropic glutamate receptor 6	0	0	1	1
Glutamate receptor 1	0	3	1	5
Glutamate receptor 3	0	3	1	5
Glutamate receptor 4	0	3	1	5
Glutamate receptor ionotropic, kainate 1	0	3	1	5
Glutamate receptor ionotropic, kainate 1	0	2	1	3
Metabotropic glutamate receptor 5	0	0	1	1
Glutamate receptor ionotropic, kainate 2	0	3	2	6
Glutamate receptor 1	0	1	1	2
Glutamate receptor 2	0	1	1	2
Glutamate receptor 3	0	0	1	1
Glutamate receptor ionotropic, kainate 3	0	3	0	4
Glutamate receptor 4	0	1	0	1
Glutamate receptor ionotropic, kainate 4	0	3	0	4
Glutamate receptor ionotropic, kainate 2	0	2	1	3
Glutamate receptor ionotropic, kainate 3	0	2	0	2
Glutamate receptor ionotropic, kainate 4	0	1	0	1
Glutamate receptor ionotropic, kainate 5	0	2	0	2
Glutamate receptor ionotropic, kainate 5	0	3	0	4
Mitogen-activated protein kinase 13	0	1	0	1
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Aryl hydrocarbon receptor	0	0	1	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Mitogen-activated protein kinase 12	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	1	0	1
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Mitogen-activated protein kinase 11	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Mitogen-activated protein kinase 14	0	1	0	1
G protein-coupled receptor GPR35	0	0	1	1
Vesicular glutamate transporter 3	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Histamine H3 receptor	0	0	1	2
Neuropeptide Y receptor type 1	0	2	0	2
Neuropeptide Y receptor type 2	0	2	0	2
Sodium/iodide cotransporter	0	1	0	1
Chain H, Igg2b-kappa 40-50 Fab (heavy Chain)	0	1	0	1
Chain L, Igg2b-kappa 40-50 Fab (light Chain)	0	1	0	1
Chain A, Na, K-ATPase alpha subunit	0	0	1	1
STAT3, partial	0	1	0	1
Kruppel-like factor 5	0	1	0	1
NPC intracellular cholesterol transporter 1 precursor	1	0	0	1
peripheral myelin protein 22 isoform 1	1	0	0	1
ras-related protein Rab-9A	1	0	0	1
signal transducer and activator of transcription 1-alpha/beta isoform alpha	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	0	0	1
Solute carrier organic anion transporter family member 1A5	0	0	0	1
Sodium/potassium-transporting ATPase subunit alpha-1	0	2	0	3
Sodium/potassium-transporting ATPase subunit beta-1	0	2	0	3
Sodium/potassium-transporting ATPase subunit alpha-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-2	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	2
Sodium/potassium-transporting ATPase subunit beta-2	0	1	0	2
Solute carrier organic anion transporter family member 1A1	0	0	0	1
Sodium/potassium-transporting ATPase subunit alpha-2	0	2	0	3
Sodium/potassium-transporting ATPase subunit beta-3	0	1	0	2
Sodium/potassium-transporting ATPase subunit gamma	0	1	0	2
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	2
Sodium/potassium-transporting ATPase subunit beta-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	0	0	1
Chain A, PUTRESCINE-BINDING PROTEIN	0	0	1	1
Chain A, S-ADENOSYLMETHIONINE DECARBOXYLASE ALPHA CHAIN	0	1	0	1
Chain B, S-ADENOSYLMETHIONINE DECARBOXYLASE BETA CHAIN	0	1	0	1
Chain A, S-ADENOSYLMETHIONINE DECARBOXYLASE ALPHA CHAIN	0	1	0	1
Chain B, S-ADENOSYLMETHIONINE DECARBOXYLASE BETA CHAIN	0	1	0	1
Ornithine decarboxylase	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
S-adenosylmethionine decarboxylase proenzyme	0	0	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Sphingosine kinase 1	0	2	0	2
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 7 subunit alpha	0	1	0	1
Sodium channel protein type 5 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Sodium channel protein type 11 subunit alpha	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	1	0	1
Sodium channel protein type 10 subunit alpha	0	1	0	1
acid sphingomyelinase	1	0	0	1
C-X-C chemokine receptor type 5 isoform 1	0	1	0	1
ubiquitin-conjugating enzyme E2 N	0	1	0	1
C-C chemokine receptor type 6	0	1	0	1
apelin receptor	0	1	0	1
DNA polymerase eta isoform 1	1	0	0	1
bcl-2-related protein A1	0	1	0	1
streptokinase A precursor	0	0	1	1
Endoglycoceramidase II	0	0	0	1
Protein kinase C alpha type	0	1	0	1
Estrogen receptor	0	0	1	1
Protein kinase C delta type	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
cAMP-dependent protein kinase catalytic subunit alpha	0	1	0	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C beta type	0	1	0	1
Estrogen receptor beta	0	0	1	1
Protein kinase C eta type	0	1	0	1
Sphingosine kinase 2	0	1	0	1
Protein kinase C theta type	0	1	0	1
guanine nucleotide-binding protein subunit alpha-15	0	1	1	2
D(3) dopamine receptor isoform e	1	0	0	1
trace amine-associated receptor 1	0	1	1	2
Phenylethanolamine N-methyltransferase	0	1	0	1
Dopamine beta-hydroxylase	0	0	0	1
5-hydroxytryptamine receptor 1D	0	0	1	1
5-hydroxytryptamine receptor 1F	0	0	1	1
5-hydroxytryptamine receptor 6	0	0	1	1
5-hydroxytryptamine receptor 5A	0	0	1	1
5-hydroxytryptamine receptor 5B	0	0	1	1
5-hydroxytryptamine receptor 3A	0	0	1	1
5-hydroxytryptamine receptor 3A	0	0	1	1
Inositol monophosphatase 1	1	0	0	1
5-hydroxytryptamine receptor 4	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
5-hydroxytryptamine receptor 3B	0	0	1	1
Chain A, Uracil-DNA Glycosylase	0	1	0	1
Protein cereblon	0	2	0	2
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Amnesic Shellfish Poisoning

Synonyms(5)

Research Excerpts

Overview

Context

Research

Studies (420)

Protein Targets (687)

Amnesic Shellfish Poisoning

Synonyms(5)

Research Excerpts

Overview

Context

Research

Studies (420)

Drugs Studied (131)

Protein Targets (687)