Page last updated: 2024-09-27

Osteochondrosis of Spine

A bone disorder involving ossification centers (EPIPHYSES) of the VERTEBRAL COLUMN.

Synonyms(2)

Synonym
Osteochondrosis of Spine
Spinal Osteochondrosis

Research

Studies (5)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's0 (0.00)12.5806
2000's1 (20.00)18.1394
2010's4 (80.00)28.8240
2020's0 (0.00)9.53
DrugIndicatedRelationship StrengthStudiesTrials
niacinamide0medium11
hydroxyproline0low10
radon0low10
trolamine salicylate0low10
fomesafen0low10
endothelin-10low10
flavin mononucleotide0medium11
inosine diphosphate0medium11

Protein Targets (48)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Endothelin-1 receptor0101
Luciferase1001
hypoxia-inducible factor 1 alpha subunit1001
progesterone receptor1001
estrogen-related nuclear receptor alpha2002
pregnane X nuclear receptor1001
estrogen nuclear receptor alpha2002
peroxisome proliferator activated receptor gamma1001
vitamin D (1,25- dihydroxyvitamin D3) receptor2002
Histone H2A.x1001
nuclear factor erythroid 2-related factor 2 isoform 11001
Neutral amino acid transporter A0101
Asc-type amino acid transporter 10101
Neutral amino acid transporter B(0)0101
Proton-coupled amino acid transporter 10101
Amino acid transporter0101
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE1001
Chain A, NAD-dependent deacetylase0101
GLI family zinc finger 31001
glucocorticoid receptor [Homo sapiens]1001
retinoic acid nuclear receptor alpha variant 11001
retinoid X nuclear receptor alpha2002
farnesoid X nuclear receptor1001
aryl hydrocarbon receptor1001
activating transcription factor 61001
Caspase-71001
caspase-31001
geminin1001
histone acetyltransferase KAT2A isoform 11001
Poly [ADP-ribose] polymerase 20101
NAD-dependent histone deacetylase SIR20101
Coagulation factor VII0101
Poly [ADP-ribose] polymerase 10101
Tissue factor0101
Cytochrome P450 3A50101
NAD-dependent protein deacetylase HST20101
Fatty-acid amide hydrolase 10101
Protein mono-ADP-ribosyltransferase PARP150101
NAD(+) hydrolase SARM10101
NAD-dependent protein deacetylase sirtuin-20101
NAD-dependent protein deacetylase sirtuin-60101
NAD-dependent protein deacetylase sirtuin-10101
ATPase family AAA domain-containing protein 51001
Ataxin-21001
NAD-dependent protein deacetylase sirtuin-3, mitochondrial0101
NAD-dependent protein deacylase sirtuin-5, mitochondrial0101
NAD-dependent protein deacetylase 0101
RAR-related orphan receptor gamma1001
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]