Accidental or deliberate use of an OPIOID in excess of normal dosage. It includes overdose for prescription and illicit opioids.
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| "Opioid overdose is a public health emergency in the United States." | ( Davis, CS; Lieberman, AJ, 2021) |
| "Opioid overdose is preventable and reversible." | ( Latkin, C; Likindikoki, S; Mbwambo, J; Nonyane, BAS; Saleem, HT, 2021) |
| "Opioid overdose is a leading cause of death in the United States." | ( Bergstein, RS; King, K; Latimore, AD; Melendez-Torres, GJ, 2021) |
| "Opioid overdoses are a major public health emergency in the United States." | ( Adams, K; Andrews-Higgins, SA; Auritt, V; Back, S; Barkowski, LK; Batty, EJ; Behrooz, MR; Bell, S; Chen, S; Christopher, MC; Coovert, N; Crable, EL; Dasgupta, A; Drainoni, ML; Goddard-Eckrich, D; Goetz, M; Hartman, JL; Heffer, H; Iftikhar, P; Jones, L; Knudsen, HK; Lang, S; Lunze, K; Martin, A; McAlearney, AS; McCrimmon, T; Reedy-Johnson, MK; Roeber, C; Scalise, AL; Sieck, CJ; Walker, DM; Walt, G; Wood, JD; Zito, P, 2022) |
| "Opioid overdoses are responsible for the majority of overdose deaths worldwide." | ( Brumwell, A; Scheibe, A; Shelly, S; Stowe, MJ; Wilson, M, 2022) |
| "Fatal opioid overdose is a significant public health problem with increasing incidence in developed countries." | ( Bradshaw, CA; Fuller, GW; John, A; Jones, J; Jones, M; Snooks, H; Watkins, A, 2022) |
| "Opioid overdose is a leading public health problem in the United States; however, national data on overdose deaths are delayed by several months or more." | ( Bowen, D; Guy, GP; Heuett, WJ; Holland, K; Jones, CM; Pressley, DP; Sumner, SA; Vivolo-Kantor, A; Zwald, ML, 2022) |
| "Fatal and nonfatal opioid overdoses are at record levels, and emergency department (ED) visits may be an opportune time to intervene." | ( Beaudoin, FL; Daly, MM; Hallowell, BD; Jacka, BP; Langdon, KJ; Li, Y; Marshall, BDL; Newman, RA; Peachey, AM; Samuels, EA, 2022) |
| "Opioid overdoses are a leading cause of preventable death in the United States." | ( Becker, WC; Black, AC; D'Onofrio, G; Fiellin, DA; Grau, LE; Greene, C; Hawk, KE; Heimer, R; Howell, BA; Lee, H; Lin, HJ, 2023) |
| "The rate of opioid overdose is markedly elevated after prison release, particularly in the first two weeks." | ( Hartung, DM; Kempany, K; McCracken, CM; Nguyen, T; Waddell, EN, 2023) |
| "Opioid overdose is a leading cause of maternal mortality, yet limited attention has been given to the consequences of opioid use disorder (OUD) in the year following delivery when most drug-related deaths occur." | ( Coulter, RWS; Frankeberger, J; Jarlenski, M; Krans, EE; Mair, C, 2023) |
| "Nonfatal opioid overdose is the leading risk factor for subsequent fatal overdose and represents a critical opportunity to reduce future overdose and mortality." | ( Bagley, SM; Beletsky, L; Carroll, JJ; Formica, SW; Green, TC; Kimmel, SD; Lambert, AM; Rosenbloom, D; Walley, AY; Xuan, Z; Yan, S, 2023) |
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| "Naloxone, the antidote for an opioid overdose, can save the life of an opioid overdose victim if it is readily available and administered quickly." | ( Hill, LG; Holleran Steiker, LK; Kinzly, ML; Mazin, L, 2020) |
| "Peers of individuals at risk of opioid overdose are well-positioned to administer naloxone and prevent overdose death." | ( Hanson, BL; Porter, RR; Terhorst-Miller, H; Zöld, AL, 2020) |
| "Patients with a history of opioid overdose (n = 274) receiving residential addiction treatment in the Midwestern United States completed self-report surveys to classify their most recent opioid overdose as unintentional, actively suicidal (wanted to die), or passively suicidal (didn't care about the risks)." | ( Bohnert, ASB; Fernandez, AC; Gicquelais, RE; Jannausch, M; Sen, S; Thomas, L, 2020) |
| "Over half of opioid overdoses among individuals in addiction treatment involved some degree of suicidal thinking." | ( Bohnert, ASB; Fernandez, AC; Gicquelais, RE; Jannausch, M; Sen, S; Thomas, L, 2020) |
| "In this review, we present trends in opioid overdose rates during this period and discuss how the proliferation of opioid prescribing to treat chronic pain, changes in the heroin and illegally manufactured opioid synthetics markets, and social factors, including deindustrialization and concentrated poverty, contributed to the rise of the overdose epidemic." | ( Cerdá, M; Friedman, SR; Hamilton, L; Keyes, KM; Krawczyk, N; Rudolph, KE, 2021) |
| "Patients may be vulnerable to opioid overdose if they attempt to override the blockade during treatment, at the end of a dosing interval, after missing a dose, or after discontinuing treatment." | ( Akerman, SC; Bloomgren, G; Desai, A; Fratantonio, J; Jain, P; Liles-Burden, MA; Marino, R; McKinnell, K; Sullivan, MA; Vunnava, P; Wenten, M, 2021) |
| "Reporting rates of opioid overdose per 10,000 patients treated were similar among latency groups: 0." | ( Akerman, SC; Bloomgren, G; Desai, A; Fratantonio, J; Jain, P; Liles-Burden, MA; Marino, R; McKinnell, K; Sullivan, MA; Vunnava, P; Wenten, M, 2021) |
| "The 2017 declaration of the opioid overdose epidemic as a public health emergency in the United States enhanced a national focus on effective and sustainable treatments for opioid use disorder (OUD), including multiple options utilizing medication." | ( Carlson, M; Howell, V; Moore, K; Schuman-Olivier, Z; Sharp, A, 2021) |
| "Naloxone effectively reverses opioid overdoses on a physiological level; however, there are outstanding questions on community THN program effectiveness (adverse events, dosing requirements, dose-response between routes of administration) and implementation (accessibility, availability, and affordability)." | ( Ali, F; Buxton, JA; Dhillon, D; Elton-Marshall, T; Ferguson, M; Leece, P; Moustaqim-Barrette, A; Ng, J; Rittenbach, K; Sundvick, K, 2021) |
| "Treatment of prehospital opioid overdose using intranasal naloxone at an initial dose of 0." | ( Brent, C; Bui, P; Herbert, L; Mills, D; Salter, J; Thompson, J; Wagner, D, 2022) |
| "Individuals with a recent ED visit for opioid overdose were in treatment for shorter duration (odds ratio [OR] 0." | ( Au, VYO; Chawar, C; Hillmer, A; Marsh, DC; Rosic, T; Samaan, Z; Sanger, N; Thabane, L; Worster, A, 2021) |
| "Medically treated opioid overdoses identify a population at high risk of subsequent mortality and need for treatment." | ( Crystal, S; Nowels, M; Olfson, M; Samples, H; Treitler, P; Williams, AR, 2021) |
| "Naloxone can reverse opioid overdoses and can be distributed and administered with minimal training." | ( Alavi, M; Christmass, M; Conway, A; Degenhardt, L; Dore, GJ; Dunlop, A; Gilliver, R; Grebely, J; Harrod, ME; Hayllar, J; Henderson, C; Lam, T; Marshall, AD; Montebello, M; Peacock, A; Read, P; Reid, D; Silk, D; Treloar, C; Valerio, H; Whitton, G, 2021) |
| "In response to the opioid overdose crisis, providers were urged to taper and discontinue patients from long-term opioid therapy; however, abrupt discontinuation may lead to poor health outcomes." | ( Beaugard, CA; Chui, KKH; Larochelle, MR; Stopka, TJ; Walley, AY; Young, LD, 2022) |
| "Adults with recreational opioid overdose who developed naloxone-associated pulmonary edema, defined as the acute onset of respiratory distress, hypoxemia, and radiographic pulmonary edema after naloxone administration for opioid intoxication, provided that gas exchange and chest imaging rapidly improved and pulmonary aspiration of gastric contents was not clinically suspected." | ( Kempainen, RR; Kummer, RL; Leatherman, JW; Olives, TD; Prekker, ME, 2022) |
| "Patients with medically-treated opioid overdose are at high risk for subsequent adverse outcomes, including repeat overdose." | ( Crystal, S; Nowels, M; Olfson, M; Samples, H; Treitler, P; Williams, AR, 2022) |
| "The primary outcome was opioid overdose (fatal and non-fatal) while on treatment, with secondary outcomes including opioid overdose (first 30 days of treatment), treatment discontinuation, health-care interactions related to treatment of opioid use disorder, receiving a weekly supply of take-home doses and opioid overdose within 30 days of treatment discontinuation." | ( Antoniou, T; Bozinoff, N; Campbell, T; Gomes, T; Mamdani, M; McCormack, D; Munro, C; Paterson, JM; Sproule, B; Tadrous, M, 2022) |
| "Risk of opioid overdose while on treatment [hazard ratio (HR) = 0." | ( Antoniou, T; Bozinoff, N; Campbell, T; Gomes, T; Mamdani, M; McCormack, D; Munro, C; Paterson, JM; Sproule, B; Tadrous, M, 2022) |
| "Since 2017, an increasing number of opioid overdoses in Oslo, Norway, has been categorized as involving unspecified opioids, as noted in the patient records by the doctor treating the patient." | ( Brekke, M; Iqbal, ZZ; Nguyen, TMT; Vallersnes, OM, 2022) |
| "Identifying Wyoming counties with high opioid overdose vulnerabilities and limited access to overdose treatment can inform public health and harm reduction responses." | ( Fowler, L; Lingwall, C; Newsky, S; Pustz, J; Shrestha, S; Stopka, TJ; Taylor, M; Van Handel, M, 2022) |
| "Higher opioid overdose mortality rates are problematic in rural communities, and there are few prevention, treatment, and recovery resources for individuals experiencing opioid use disorder." | ( Cody, SL; Glenn, CJ; Hines, CB; Newman, S; Sharp-Marbury, R, 2023) |
| "Higher opioid overdose mortality rates are problematic in rural communities, and there are few prevention, treatment, and recovery resources for individuals experiencing opioid use disorder." | ( Cody, SL; Glenn, CJ; Hines, CB; Newman, S; Sharp-Marbury, R, 2023) |
| "Higher opioid overdose mortality rates are problematic in rural communities, and there are few prevention, treatment, and recovery resources for individuals experiencing opioid use disorder." | ( Cody, SL; Glenn, CJ; Hines, CB; Newman, S; Sharp-Marbury, R, 2023) |
| "One of the most robust tools to combat opioid overdose deaths is buprenorphine, a partial opioid agonist, and gold standard medication treatment for OUD, but only 5% of the prescribing workforce possess the required Drug Enforcement Agency (DEA) X waiver." | ( Hailer, L; Jones, KF; O'Reilly Jacob, M; Spetz, J; Tierney, M, 2023) |
| "Clinical opioid overdose risk prediction models can be useful tools to reduce the risk of overdose in patients prescribed long-term opioid therapy (LTOT)." | ( Binswanger, IA; Fairbairn, LM; Glanz, JM; Narwaney, KJ; Nguyen, AP; Wright, L; Zeng, C, 2023) |
| "We obtain annual county-level counts of opioid overdose deaths, treatment admissions for opioid misuse, and newly diagnosed cases of acute and chronic hepatitis C and newly diagnosed HIV from 2014 to 2019." | ( Bonny, A; Hepler, SA; Kline, D; McKnight, E; Miller, WC; Waller, LA, 2023) |
| "Given the ongoing burden of opioid overdoses, continued multipronged efforts are needed to remove barriers to buprenorphine care and increase availability of this lifesaving treatment." | ( Christine, PJ; Larochelle, MR; Lin, LA; McBride, J; Tipirneni, R, 2023) |
| "Opioid use disorder and opioid overdose continue to be significant public health challenges despite the availability of effective treatments." | ( France, CP; Maguire, DR, 2024) |