Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
Chain A, HADH2 protein | 1 | 0 | 0 | 1 |
Chain B, HADH2 protein | 1 | 0 | 0 | 1 |
hypoxia-inducible factor 1 alpha subunit | 3 | 0 | 0 | 3 |
RAR-related orphan receptor gamma | 3 | 0 | 0 | 3 |
GLI family zinc finger 3 | 2 | 0 | 0 | 2 |
AR protein | 3 | 0 | 0 | 3 |
aldehyde dehydrogenase 1 family, member A1 | 1 | 0 | 0 | 1 |
nuclear receptor subfamily 1, group I, member 3 | 2 | 0 | 0 | 2 |
progesterone receptor | 3 | 0 | 0 | 3 |
retinoic acid nuclear receptor alpha variant 1 | 3 | 0 | 0 | 3 |
estrogen-related nuclear receptor alpha | 4 | 0 | 0 | 4 |
pregnane X nuclear receptor | 2 | 0 | 0 | 2 |
estrogen nuclear receptor alpha | 4 | 0 | 0 | 4 |
thyroid stimulating hormone receptor | 1 | 0 | 0 | 1 |
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | 2 | 0 | 0 | 2 |
v-jun sarcoma virus 17 oncogene homolog (avian) | 2 | 0 | 0 | 2 |
Histone H2A.x | 1 | 0 | 0 | 1 |
potassium voltage-gated channel subfamily H member 2 isoform d | 2 | 0 | 0 | 2 |
thyroid hormone receptor beta isoform 2 | 2 | 0 | 0 | 2 |
heat shock protein beta-1 | 2 | 0 | 0 | 2 |
nuclear factor erythroid 2-related factor 2 isoform 1 | 3 | 0 | 0 | 3 |
ATP-binding cassette sub-family C member 3 | 0 | 4 | 0 | 4 |
Multidrug resistance-associated protein 4 | 0 | 4 | 0 | 4 |
5-hydroxytryptamine receptor 4 | 0 | 6 | 0 | 6 |
Voltage-dependent calcium channel gamma-2 subunit | 3 | 0 | 0 | 3 |
Bile salt export pump | 0 | 5 | 0 | 5 |
Cellular tumor antigen p53 | 4 | 0 | 0 | 4 |
Aldo-keto reductase family 1 member B1 | 0 | 3 | 0 | 3 |
Muscarinic acetylcholine receptor M2 | 0 | 3 | 1 | 4 |
Muscarinic acetylcholine receptor M4 | 0 | 2 | 0 | 2 |
Muscarinic acetylcholine receptor M5 | 0 | 2 | 0 | 2 |
Alpha-2A adrenergic receptor | 0 | 5 | 2 | 8 |
Cytochrome P450 2D6 | 0 | 2 | 0 | 2 |
Muscarinic acetylcholine receptor M1 | 0 | 3 | 1 | 4 |
Alpha-2B adrenergic receptor | 0 | 4 | 1 | 6 |
Glutamate receptor 2 | 3 | 0 | 0 | 3 |
Muscarinic acetylcholine receptor M3 | 0 | 3 | 1 | 4 |
Sodium-dependent noradrenaline transporter | 0 | 2 | 0 | 2 |
Alpha-1D adrenergic receptor | 0 | 4 | 1 | 6 |
5-hydroxytryptamine receptor 2A | 0 | 6 | 1 | 7 |
5-hydroxytryptamine receptor 2C | 0 | 6 | 1 | 7 |
Histamine H1 receptor | 0 | 2 | 0 | 2 |
5-hydroxytryptamine receptor 2B | 0 | 6 | 1 | 7 |
Nuclear receptor ROR-gamma | 3 | 0 | 0 | 3 |
Inositol monophosphatase 1 | 1 | 0 | 0 | 1 |
Sodium-dependent dopamine transporter | 0 | 2 | 0 | 2 |
Canalicular multispecific organic anion transporter 1 | 0 | 4 | 0 | 4 |
Sigma non-opioid intracellular receptor 1 | 0 | 4 | 0 | 4 |
Adenylate cyclase | 0 | 1 | 0 | 1 |
Tyrosine-protein kinase Lck | 0 | 1 | 0 | 1 |
Tyrosine-protein kinase Fyn | 0 | 1 | 0 | 1 |
ATP-dependent translocase ABCB1 | 0 | 1 | 0 | 1 |
Beta-2 adrenergic receptor | 0 | 4 | 1 | 5 |
ATP-dependent translocase ABCB1 | 0 | 4 | 0 | 4 |
Beta-1 adrenergic receptor | 0 | 4 | 1 | 5 |
Cytochrome P450 3A4 | 0 | 2 | 0 | 2 |
D(2) dopamine receptor | 0 | 3 | 1 | 4 |
Alpha-2C adrenergic receptor | 0 | 3 | 2 | 6 |
5-hydroxytryptamine receptor 1A | 0 | 4 | 1 | 6 |
ATP-dependent translocase ABCB1 | 0 | 1 | 0 | 1 |
D(1A) dopamine receptor | 0 | 3 | 1 | 4 |
Sodium-dependent dopamine transporter | 0 | 2 | 0 | 2 |
Thromboxane-A synthase | 0 | 2 | 0 | 2 |
5-hydroxytryptamine receptor 1D | 0 | 1 | 0 | 1 |
5-hydroxytryptamine receptor 1B | 0 | 3 | 1 | 4 |
5-hydroxytryptamine receptor 1B | 0 | 4 | 0 | 4 |
D(3) dopamine receptor | 0 | 2 | 0 | 2 |
5-hydroxytryptamine receptor 5A | 0 | 1 | 0 | 1 |
5-hydroxytryptamine receptor 6 | 0 | 4 | 1 | 5 |
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 1 | 0 | 0 | 1 |
Chain A, membrane-associated prostaglandin E synthase-2 | 0 | 1 | 0 | 1 |
Chain A, Putative fructose-1,6-bisphosphate aldolase | 1 | 0 | 0 | 1 |
Chain A, 2-oxoglutarate Oxygenase | 1 | 0 | 0 | 1 |
Chain A, Cruzipain | 1 | 0 | 0 | 1 |
Luciferase | 2 | 0 | 0 | 2 |
interleukin 8 | 1 | 0 | 0 | 1 |
SMAD family member 2 | 1 | 0 | 0 | 1 |
SMAD family member 3 | 1 | 0 | 0 | 1 |
TDP1 protein | 3 | 0 | 0 | 3 |
Microtubule-associated protein tau | 1 | 0 | 0 | 1 |
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 1 | 0 | 0 | 1 |
estrogen receptor 2 (ER beta) | 1 | 0 | 0 | 1 |
cytochrome P450 family 3 subfamily A polypeptide 4 | 2 | 0 | 0 | 2 |
EWS/FLI fusion protein | 1 | 0 | 0 | 1 |
glucocorticoid receptor [Homo sapiens] | 3 | 0 | 0 | 3 |
retinoid X nuclear receptor alpha | 1 | 0 | 0 | 1 |
farnesoid X nuclear receptor | 2 | 0 | 0 | 2 |
G | 1 | 0 | 0 | 1 |
67.9K protein | 1 | 0 | 0 | 1 |
glucocerebrosidase | 1 | 0 | 0 | 1 |
Parkin | 1 | 0 | 0 | 1 |
bromodomain adjacent to zinc finger domain 2B | 1 | 0 | 0 | 1 |
peroxisome proliferator-activated receptor delta | 1 | 0 | 0 | 1 |
peroxisome proliferator activated receptor gamma | 2 | 0 | 0 | 2 |
vitamin D (1,25- dihydroxyvitamin D3) receptor | 1 | 0 | 0 | 1 |
euchromatic histone-lysine N-methyltransferase 2 | 2 | 0 | 0 | 2 |
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 1 | 0 | 0 | 1 |
aryl hydrocarbon receptor | 2 | 0 | 0 | 2 |
cytochrome P450 2D6 isoform 1 | 1 | 0 | 0 | 1 |
peripheral myelin protein 22 isoform 1 | 1 | 0 | 0 | 1 |
cytochrome P450 2C9 precursor | 1 | 0 | 0 | 1 |
vitamin D3 receptor isoform VDRA | 1 | 0 | 0 | 1 |
thyroid hormone receptor beta isoform a | 2 | 0 | 0 | 2 |
ras-related protein Rab-9A | 1 | 0 | 0 | 1 |
serine/threonine-protein kinase mTOR isoform 1 | 1 | 0 | 0 | 1 |
DNA polymerase iota isoform a (long) | 1 | 0 | 0 | 1 |
nuclear receptor ROR-gamma isoform 1 | 1 | 0 | 0 | 1 |
DNA polymerase kappa isoform 1 | 1 | 0 | 0 | 1 |
M-phase phosphoprotein 8 | 1 | 0 | 0 | 1 |
lamin isoform A-delta10 | 1 | 0 | 0 | 1 |
neuropeptide S receptor isoform A | 1 | 0 | 0 | 1 |
Prostaglandin-H2 D-isomerase | 0 | 1 | 0 | 1 |
Prostaglandin E synthase | 0 | 1 | 0 | 1 |
Solute carrier family 22 member 6 | 0 | 1 | 0 | 1 |
Prostaglandin G/H synthase 1 | 0 | 1 | 0 | 2 |
Prostaglandin G/H synthase 2 | 0 | 1 | 0 | 2 |
3',5'-cyclic-AMP phosphodiesterase | 0 | 1 | 0 | 1 |
Solute carrier organic anion transporter family member 2B1 | 0 | 2 | 0 | 2 |
Cytochrome c oxidase subunit 2 | 0 | 1 | 0 | 1 |
Epidermal growth factor receptor | 0 | 1 | 0 | 1 |
Phospholipase A2, major isoenzyme | 0 | 1 | 0 | 1 |
Interferon beta | 2 | 0 | 0 | 2 |
HLA class I histocompatibility antigen, B alpha chain | 1 | 0 | 0 | 1 |
Albumin | 0 | 1 | 2 | 3 |
Prostaglandin G/H synthase 1 | 0 | 2 | 0 | 3 |
Procathepsin L | 0 | 1 | 0 | 1 |
Neuronal acetylcholine receptor subunit alpha-4 | 0 | 1 | 0 | 1 |
Interleukin-8 | 0 | 1 | 0 | 1 |
Androgen receptor | 0 | 2 | 1 | 3 |
Neuronal acetylcholine receptor subunit beta-2 | 0 | 1 | 0 | 1 |
Polyunsaturated fatty acid 5-lipoxygenase | 0 | 1 | 0 | 2 |
Aldo-keto reductase family 1 member B1 | 0 | 1 | 0 | 1 |
Aldo-keto reductase family 1 member B1 | 0 | 1 | 0 | 1 |
Aldo-keto reductase family 1 member C4 | 0 | 1 | 0 | 1 |
Prostaglandin G/H synthase 1 | 0 | 1 | 0 | 1 |
Prostaglandin G/H synthase 1 | 0 | 1 | 0 | 1 |
Sodium- and chloride-dependent GABA transporter 1 | 0 | 1 | 0 | 1 |
Adenosine receptor A1 | 0 | 1 | 0 | 1 |
Serum paraoxonase/arylesterase 1 | 0 | 1 | 0 | 1 |
Indoleamine 2,3-dioxygenase 1 | 0 | 1 | 0 | 1 |
Caspase-1 | 0 | 0 | 0 | 1 |
Nitric oxide synthase, inducible | 0 | 1 | 0 | 1 |
Adenosine receptor A2a | 0 | 1 | 0 | 1 |
Substance-P receptor | 0 | 1 | 0 | 1 |
Prostaglandin E2 receptor EP3 subtype | 0 | 1 | 0 | 1 |
Sodium- and chloride-dependent GABA transporter 2 | 0 | 1 | 0 | 1 |
Sodium- and chloride-dependent GABA transporter 3 | 0 | 1 | 0 | 1 |
Prostaglandin E2 receptor EP4 subtype | 0 | 1 | 0 | 1 |
Multidrug resistance-associated protein 1 | 0 | 1 | 0 | 1 |
Bifunctional epoxide hydrolase 2 | 0 | 1 | 0 | 1 |
Prostaglandin G/H synthase 2 | 0 | 3 | 1 | 4 |
Prostaglandin G/H synthase 2 | 0 | 1 | 0 | 1 |
Prostaglandin E2 receptor EP1 subtype | 0 | 1 | 0 | 1 |
Peroxisome proliferator-activated receptor gamma | 0 | 0 | 1 | 1 |
Aldo-keto reductase family 1 member C3 | 0 | 2 | 0 | 2 |
Histamine H2 receptor | 1 | 0 | 0 | 1 |
Sodium- and chloride-dependent betaine transporter | 0 | 1 | 0 | 1 |
C-X-C chemokine receptor type 3 | 0 | 1 | 0 | 1 |
Aldo-keto reductase family 1 member C2 | 0 | 1 | 0 | 1 |
Spike glycoprotein | 1 | 0 | 0 | 1 |
Guanine nucleotide-binding protein G | 1 | 0 | 0 | 1 |
Prostaglandin D2 receptor | 0 | 2 | 0 | 2 |
Solute carrier organic anion transporter family member 1A3 | 0 | 1 | 0 | 1 |
Prostaglandin G/H synthase 2 | 0 | 2 | 0 | 2 |
Lactoylglutathione lyase | 0 | 1 | 0 | 1 |
Aldo-keto reductase family 1 member C1 | 0 | 1 | 0 | 1 |
Prostaglandin G/H synthase 2 | 0 | 1 | 0 | 2 |
Potassium voltage-gated channel subfamily H member 2 | 0 | 2 | 0 | 2 |
Uracil nucleotide/cysteinyl leukotriene receptor | 0 | 1 | 0 | 1 |
Solute carrier family 22 member 6 | 0 | 1 | 0 | 1 |
Solute carrier family 22 member 7 | 0 | 0 | 0 | 1 |
Sigma intracellular receptor 2 | 0 | 1 | 0 | 1 |
Prostaglandin E2 receptor EP2 subtype | 0 | 1 | 0 | 1 |
Rho-associated protein kinase 2 | 0 | 1 | 0 | 1 |
Prostaglandin G/H synthase 1 | 0 | 1 | 0 | 1 |
Nicotinate phosphoribosyltransferase | 0 | 1 | 0 | 1 |
Solute carrier family 22 member 8 | 0 | 1 | 0 | 1 |
Inositol hexakisphosphate kinase 1 | 1 | 0 | 0 | 1 |
Multidrug and toxin extrusion protein 1 | 0 | 1 | 0 | 1 |
Dehydrogenase/reductase SDR family member 9 | 0 | 1 | 0 | 1 |
P2Y purinoceptor 12 | 0 | 1 | 0 | 1 |
Solute carrier organic anion transporter family member 1B3 | 0 | 2 | 0 | 2 |
Cytosolic phospholipase A2 gamma | 0 | 1 | 0 | 1 |
Prostaglandin D2 receptor 2 | 0 | 1 | 1 | 2 |
Solute carrier organic anion transporter family member 1B1 | 0 | 2 | 0 | 2 |
cytochrome P450 2C9, partial | 1 | 0 | 0 | 1 |
luciferase | 0 | 0 | 0 | 1 |
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 2 | 0 | 0 | 2 |
nuclear receptor subfamily 1, group I, member 2 | 1 | 0 | 0 | 1 |
nuclear factor erythroid 2-related factor 2 isoform 2 | 1 | 0 | 0 | 1 |
Fatty acid-binding protein, liver | 0 | 1 | 0 | 1 |
Estrogen receptor | 0 | 2 | 0 | 2 |
Glucocorticoid receptor | 0 | 2 | 1 | 8 |
Progesterone receptor | 0 | 2 | 0 | 3 |
Glucocorticoid receptor | 0 | 1 | 1 | 2 |
Glucocorticoid receptor | 0 | 0 | 1 | 1 |
Glycine receptor subunit alpha-1 | 0 | 2 | 0 | 2 |
Corticosteroid-binding globulin | 0 | 1 | 0 | 1 |
Mineralocorticoid receptor | 0 | 2 | 1 | 3 |
Cytochrome P450 2C9 | 0 | 2 | 0 | 2 |
Glutamine synthetase | 0 | 0 | 1 | 1 |
Androgen receptor | 0 | 1 | 0 | 1 |
Glycine receptor subunit beta | 0 | 2 | 0 | 2 |
Glycine receptor subunit alpha-2 | 0 | 2 | 0 | 2 |
Glycine receptor subunit alpha-3 | 0 | 2 | 0 | 2 |
Histamine H1 receptor | 0 | 0 | 1 | 1 |
Nociceptin receptor | 0 | 0 | 1 | 1 |
Cytochrome P450 2J2 | 0 | 2 | 0 | 2 |
Estrogen receptor beta | 0 | 2 | 0 | 2 |
ATPase family AAA domain-containing protein 5 | 2 | 0 | 0 | 2 |
Ataxin-2 | 3 | 0 | 0 | 3 |
thioredoxin reductase | 1 | 0 | 0 | 1 |
Beta-1 adrenergic receptor | 0 | 1 | 1 | 3 |
arylsulfatase A | 1 | 0 | 0 | 1 |
D(1A) dopamine receptor | 1 | 0 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit pi | 0 | 1 | 1 | 2 |
Solute carrier family 22 member 1 | 0 | 1 | 0 | 1 |
Voltage-dependent L-type calcium channel subunit alpha-1C | 0 | 1 | 0 | 1 |
Bile salt export pump | 0 | 2 | 0 | 2 |
Cytochrome P450 1A2 | 0 | 1 | 0 | 1 |
5-hydroxytryptamine receptor 1A | 0 | 1 | 0 | 1 |
Adenosine receptor A3 | 0 | 1 | 1 | 2 |
Beta-2 adrenergic receptor | 0 | 2 | 0 | 3 |
Cytochrome P450 2C8 | 0 | 1 | 0 | 1 |
Beta-3 adrenergic receptor | 0 | 2 | 1 | 3 |
Gamma-aminobutyric acid receptor subunit beta-1 | 0 | 1 | 1 | 2 |
Alpha-1B adrenergic receptor | 0 | 1 | 1 | 2 |
Beta-1 adrenergic receptor | 0 | 2 | 1 | 4 |
Gamma-aminobutyric acid receptor subunit delta | 0 | 1 | 1 | 2 |
Gamma-aminobutyric acid receptor subunit gamma-2 | 0 | 1 | 1 | 2 |
D(3) dopamine receptor | 0 | 1 | 0 | 1 |
Alpha-2B adrenergic receptor | 0 | 0 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-5 | 0 | 1 | 1 | 2 |
Gamma-aminobutyric acid receptor subunit alpha-3 | 0 | 1 | 1 | 2 |
Voltage-dependent L-type calcium channel subunit alpha-1C | 0 | 1 | 0 | 1 |
Alpha-2C adrenergic receptor | 0 | 0 | 1 | 1 |
Alpha-2A adrenergic receptor | 0 | 0 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit gamma-1 | 0 | 1 | 1 | 2 |
Gamma-aminobutyric acid receptor subunit alpha-2 | 0 | 1 | 1 | 2 |
Alpha-1D adrenergic receptor | 0 | 1 | 1 | 2 |
Endothelin-1 receptor | 0 | 1 | 1 | 2 |
Beta-3 adrenergic receptor | 0 | 2 | 0 | 2 |
Gamma-aminobutyric acid receptor subunit alpha-4 | 0 | 1 | 1 | 2 |
Gamma-aminobutyric acid receptor subunit gamma-3 | 0 | 1 | 1 | 2 |
Adenosine receptor A2a | 0 | 1 | 1 | 2 |
Neuromedin-K receptor | 0 | 0 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-6 | 0 | 1 | 1 | 2 |
Type-1 angiotensin II receptor | 0 | 1 | 1 | 2 |
Sodium-dependent serotonin transporter | 0 | 2 | 0 | 2 |
Cholecystokinin receptor type A | 0 | 1 | 1 | 2 |
Cytochrome P450 2C19 | 0 | 1 | 0 | 1 |
5-hydroxytryptamine receptor 7 | 0 | 1 | 1 | 2 |
Beta-1 adrenergic receptor | 0 | 1 | 0 | 1 |
Alpha-1A adrenergic receptor | 0 | 1 | 2 | 4 |
Alpha-1B adrenergic receptor | 0 | 0 | 1 | 2 |
Mu-type opioid receptor | 0 | 1 | 1 | 2 |
Vasopressin V1a receptor | 0 | 1 | 1 | 2 |
Delta-type opioid receptor | 0 | 1 | 1 | 2 |
Kappa-type opioid receptor | 0 | 1 | 1 | 2 |
Alpha-1A adrenergic receptor | 0 | 1 | 1 | 2 |
5-hydroxytryptamine receptor 7 | 0 | 1 | 0 | 1 |
Beta-2 adrenergic receptor | 0 | 1 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-1 | 0 | 1 | 1 | 2 |
Gamma-aminobutyric acid receptor subunit beta-3 | 0 | 1 | 1 | 2 |
Gamma-aminobutyric acid receptor subunit beta-2 | 0 | 1 | 1 | 2 |
Voltage-dependent L-type calcium channel subunit alpha-1C | 0 | 1 | 0 | 1 |
Sodium channel protein type 5 subunit alpha | 0 | 1 | 0 | 1 |
Sodium/bile acid cotransporter | 0 | 1 | 0 | 1 |
Beta-2 adrenergic receptor | 0 | 1 | 1 | 3 |
GABA theta subunit | 0 | 1 | 1 | 2 |
Gamma-aminobutyric acid receptor subunit epsilon | 0 | 1 | 1 | 2 |
Nuclear receptor subfamily 2 group E member 1 | 0 | 0 | 2 | 2 |
Chain A, TYROSYL-DNA PHOSPHODIESTERASE | 1 | 0 | 0 | 1 |
pregnane X receptor | 1 | 0 | 0 | 1 |
Cocaine esterase | 0 | 1 | 0 | 1 |
Histone deacetylase 3 | 0 | 2 | 0 | 2 |
UDP-glucuronosyltransferase 1A9 | 0 | 0 | 0 | 1 |
Cytochrome P450 2A6 | 0 | 1 | 0 | 1 |
Tissue factor | 0 | 1 | 0 | 1 |
Aldo-keto reductase family 1 member A1 | 0 | 1 | 0 | 1 |
UDP-glucuronosyltransferase 2B7 | 0 | 1 | 0 | 2 |
UDP-glucuronosyltransferase 1-6 | 0 | 0 | 0 | 1 |
Liver carboxylesterase 1 | 0 | 1 | 0 | 1 |
Aldo-keto reductase family 1 member A1 | 0 | 1 | 0 | 1 |
Histone deacetylase 4 | 0 | 2 | 0 | 2 |
Histone deacetylase 1 | 0 | 2 | 0 | 2 |
Aldo-keto reductase family 1 member A1 | 0 | 1 | 0 | 1 |
Aldo-keto reductase family 1 member B7 | 0 | 1 | 0 | 1 |
Sigma non-opioid intracellular receptor 1 | 0 | 1 | 0 | 1 |
Histone deacetylase 7 | 0 | 2 | 0 | 2 |
Histone deacetylase 2 | 0 | 2 | 0 | 2 |
Polyamine deacetylase HDAC10 | 0 | 2 | 0 | 2 |
Histone deacetylase 11 | 0 | 2 | 0 | 2 |
Histone deacetylase 8 | 0 | 2 | 0 | 2 |
NAD-dependent protein deacylase sirtuin-5, mitochondrial | 0 | 1 | 0 | 1 |
Histone deacetylase 6 | 0 | 2 | 0 | 2 |
Histone deacetylase 9 | 0 | 2 | 0 | 2 |
Histone deacetylase 5 | 0 | 2 | 0 | 2 |
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |