Non-communicable Chronic Diseases

Diseases which are typically non-infectious in origin and do not transmit from an affected individual to others. The four main types of noncommunicable diseases are CARDIOVASCULAR DISEASES (e.g., heart attacks and stroke), CANCER, chronic respiratory diseases (e.g., CHRONIC OBSTRUCTIVE PULMONARY DISEASE and ASTHMA) and DIABETES MELLITUS.

Synonym
Non-communicable Chronic Diseases
Noninfectious Diseases
Noncommunicable Diseases
Non-infectious Diseases
Non-communicable Diseases

Excerpt	Reference
"As the burden of noncommunicable diseases grows, access to safe medical therapy is increasing in importance."	( Makinde, O; Ndichu, ET; Ohiri, K; Schulman, K; Sekoni, O, 2019)
"Treatment of noncommunicable diseases in this setting will require efforts to monitor and assure drug quality."	( Makinde, O; Ndichu, ET; Ohiri, K; Schulman, K; Sekoni, O, 2019)
"Of this, prevention and treatment of noncommunicable diseases account for US$ 36."	( Banzon, EP; Chin, B; Gelband, H; Jamison, DT; Jha, P; Khetrapal, S; Malhotra, V; Ra, S; Watkins, D; Wu, DC, 2020)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	0 (0.00)	23.3326
1990's	0 (0.00)	12.5806
2000's	0 (0.00)	18.1394
2010's	95 (33.93)	28.8240
2020's	185 (66.07)	9.53

Drug	Relationship Strength	Studies	Trials
lactic acid	low	1	0
dimethyl sulfoxide	low	1	0
hydrogen	low	1	0
phytic acid	low	1	0
melatonin	low	2	0
trimethyloxamine	medium	3	2
uracil	low	1	0
acetaminophen	low	1	0
albuterol	low	1	0
amlodipine	low	1	0
aspirin	low	2	0
caffeine	low	1	0
cyproheptadine	low	1	0
diazepam	low	1	0
isoniazid	low	1	0
metformin	low	2	0
nicardipine	medium	1	1
nifedipine	low	1	0
praziquantel	low	1	0
thyroxine	low	1	0
lysine	low	2	0
leucine	low	1	0
tryptophan	low	1	0
arginine	low	2	0
phencyclidine	low	1	0
bisphenol a	low	1	0
visnagin	low	1	0
4-cymene	low	1	0
d-alpha tocopherol	low	1	0
tocopherols	low	1	0
s,n,n'-tripropylthiocarbamate	low	1	0
raspberry ketone	low	1	0
titanium	low	1	0
galactose	low	1	0
trolamine salicylate	low	8	0
fluorides	low	1	0
cetylpyridinium chloride anhydrous	low	7	0
amoxicillin	low	1	0
simvastatin	low	1	0
ranolazine	low	1	0
trazodone hydrochloride	low	1	0
7-ketocholesterol	low	1	0
homocysteine	low	1	0
cobalt	low	1	0
aaptamine	low	1	0
methotrexate	low	1	0
resveratrol	low	1	0
retinol	low	1	0
cocaine	low	1	0
tenofovir	low	1	0
curcumin	low	1	0
D-fructopyranose	low	2	0
freedom	low	1	0
quercetin	low	2	0
bilirubin	low	1	0
linoleic acid	low	1	0
vitamin k semiquinone radical	low	1	0
alpha-linolenic acid	low	1	0
coenzyme q10	low	1	0
morphine	low	1	0
dexmedetomidine	medium	1	1
arsenic	low	1	0
selenium	low	1	0
beta-escin	low	1	0
tocotrienols	low	1	0
phytosterols	low	1	0
thymosin beta(4)	low	1	0
(9R)-9-chloro-11,17-dihydroxy-17-(2-hydroxy-1-oxoethyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one	low	1	0
ubiquinone	low	1	0
chitosan	low	1	0
tops	low	1	0
thymosin	low	1	0
semaglutide	low	4	0
diospyros	low	1	0
exudates	medium	15	1
folic acid	low	2	0
inosine pranobex	low	1	0
cyclic guanosine monophosphate-adenosine monophosphate	low	1	0
eye	low	1	0
leptin	low	3	0

Protein Targets (1,124)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
IDH1	8	0	0	8
chromobox protein homolog 1	15	0	0	15
geminin	20	0	0	20
GLI family zinc finger 3	22	0	0	22
retinoic acid nuclear receptor alpha variant 1	23	0	0	23
pregnane X nuclear receptor	16	0	0	16
Secreted chorismate mutase	0	1	0	1
TDP1 protein	18	0	0	18
serine/threonine-protein kinase PLK1	6	0	0	6
DNA polymerase iota isoform a (long)	14	0	0	14
Rap guanine nucleotide exchange factor 3	5	0	0	5
NPC1-like intracellular cholesterol transporter 1	0	0	1	1
Acetylcholine receptor subunit alpha	0	1	0	1
Acetylcholine receptor subunit beta	0	1	0	1
Acetylcholine receptor subunit gamma	0	1	0	1
Acetylcholine receptor subunit delta	0	1	0	1
Acetylcholine-binding protein	0	1	0	1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1	0	1	0	1
Endothelial PAS domain-containing protein 1	0	0	1	1
RAR-related orphan receptor gamma	19	0	0	19
ATAD5 protein, partial	9	0	0	9
GLS protein	14	0	0	14
Microtubule-associated protein tau	13	0	0	13
Smad3	6	0	0	6
aldehyde dehydrogenase 1 family, member A1	17	0	0	17
thyroid stimulating hormone receptor	13	0	0	13
nuclear receptor subfamily 1, group I, member 3	18	0	0	18
progesterone receptor	13	0	0	13
EWS/FLI fusion protein	12	0	0	13
retinoid X nuclear receptor alpha	19	0	0	19
estrogen-related nuclear receptor alpha	26	0	0	26
estrogen nuclear receptor alpha	30	0	0	30
peroxisome proliferator activated receptor gamma	18	0	0	18
aryl hydrocarbon receptor	11	0	0	11
thyroid hormone receptor beta isoform 2	20	0	0	20
peripheral myelin protein 22	11	0	0	11
cytochrome P450 3A4 isoform 1	15	0	0	15
Gamma-aminobutyric acid receptor subunit pi	15	2	1	18
ATP-binding cassette sub-family C member 3	0	17	0	17
Multidrug resistance-associated protein 4	0	17	0	19
Solute carrier family 22 member 6	0	2	0	2
Carbonic anhydrase 12	0	3	0	4
UDP-glucuronosyltransferase 1A9	0	0	0	1
Bile salt export pump	0	6	0	6
Voltage-dependent calcium channel gamma-2 subunit	12	0	0	12
Bile salt export pump	0	20	0	20
Cytochrome P450 2B1	0	0	0	1
Cytochrome P450 1A1	0	0	0	1
Carbonic anhydrase 1	0	7	0	8
Carbonic anhydrase 2	0	7	1	9
Myoglobin	0	1	0	1
Cytochrome P450 1A1	0	4	2	7
Cytochrome P450 1A2	0	5	0	6
Prostaglandin G/H synthase 1	0	5	1	6
Carbonic anhydrase 3	0	3	0	4
Cytochrome P450 3A4	0	9	1	11
Cytochrome P450 2D6	0	4	0	4
Cytochrome P450 2C9	0	7	0	7
Polyunsaturated fatty acid lipoxygenase ALOX15	0	4	0	4
Gamma-aminobutyric acid receptor subunit beta-1	15	2	1	18
Sulfotransferase 1A1	0	0	0	1
Gamma-aminobutyric acid receptor subunit delta	15	2	1	18
Gamma-aminobutyric acid receptor subunit gamma-2	15	2	1	18
UDP-glucuronosyltransferase 1-6	0	0	0	1
Glutamate receptor 2	12	0	0	12
Gamma-aminobutyric acid receptor subunit alpha-5	15	2	1	18
Gamma-aminobutyric acid receptor subunit alpha-3	15	2	1	18
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	1	0	2
Carbonic anhydrase 4	0	4	0	5
Prostaglandin G/H synthase 1	0	6	0	6
Carbonic anhydrase 6	0	3	0	4
Gamma-aminobutyric acid receptor subunit gamma-1	15	2	1	18
Gamma-aminobutyric acid receptor subunit alpha-2	15	2	1	18
Gamma-aminobutyric acid receptor subunit alpha-4	15	2	1	18
Gamma-aminobutyric acid receptor subunit gamma-3	15	2	1	18
Gamma-aminobutyric acid receptor subunit alpha-6	15	2	1	18
Carbonic anhydrase 5A, mitochondrial	0	3	0	4
Prostaglandin G/H synthase 2	0	6	0	7
Carbonic anhydrase 7	0	3	0	4
Nuclear receptor ROR-gamma	8	0	0	8
Cytochrome P450 2J2	0	4	0	4
Gamma-aminobutyric acid receptor subunit alpha-1	15	3	1	19
Gamma-aminobutyric acid receptor subunit beta-3	15	2	1	18
Gamma-aminobutyric acid receptor subunit beta-2	15	2	1	18
Carbonic anhydrase 9	0	3	0	4
GABA theta subunit	15	2	1	18
Canalicular multispecific organic anion transporter 1	0	15	0	15
Carbonic anhydrase 15	0	3	0	4
Carbonic anhydrase 13	0	2	0	3
Gamma-aminobutyric acid receptor subunit epsilon	15	2	1	18
Carbonic anhydrase 14	0	3	0	4
Carbonic anhydrase 5B, mitochondrial	0	3	0	4
toxin B	0	0	0	1
glp-1 receptor, partial	5	0	0	5
thioredoxin reductase	18	0	0	18
regulator of G-protein signaling 4	10	0	0	10
NPYLR7B	0	0	1	1
arylsulfatase A	6	0	0	6
euchromatic histone-lysine N-methyltransferase 2	22	0	0	22
thyroid stimulating hormone receptor	11	0	0	11
flap endonuclease 1	8	0	0	8
Beta-2 adrenergic receptor	0	2	2	4
Beta-1 adrenergic receptor	0	0	2	2
60 kDa chaperonin	0	2	0	2
60 kDa heat shock protein, mitochondrial	0	2	0	2
Beta-3 adrenergic receptor	0	0	1	1
Delta-type opioid receptor	0	3	2	6
10 kDa heat shock protein, mitochondrial	0	2	0	2
Thiosulfate sulfurtransferase	0	2	0	2
Beta-2 adrenergic receptor	0	0	1	3
60 kDa chaperonin	0	2	0	2
10 kDa chaperonin	0	2	0	2
Beta-2 adrenergic receptor	0	2	2	5
ATP-dependent phosphofructokinase	13	0	0	13
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	11	0	0	11
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	12	0	0	12
Chain A, Beta-lactamase	6	0	0	6
Chain A, HADH2 protein	15	0	0	15
Chain B, HADH2 protein	15	0	0	15
Chain A, 2-oxoglutarate Oxygenase	15	0	0	15
Chain A, ATP-DEPENDENT DNA HELICASE Q1	3	0	0	3
Chain A, Cruzipain	5	0	0	5
Luciferase	9	0	0	9
15-lipoxygenase, partial	7	0	0	7
WRN	2	0	0	2
phosphopantetheinyl transferase	14	0	0	14
hypoxia-inducible factor 1 alpha subunit	7	0	0	7
SMAD family member 2	9	0	0	9
USP1 protein, partial	15	0	0	15
SMAD family member 3	9	0	0	9
AR protein	25	0	0	25
thioredoxin glutathione reductase	5	0	0	5
estrogen receptor 2 (ER beta)	14	0	0	14
glucocorticoid receptor [Homo sapiens]	16	0	0	16
farnesoid X nuclear receptor	12	0	0	12
peroxisome proliferator-activated receptor delta	14	0	0	14
vitamin D (1,25- dihydroxyvitamin D3) receptor	16	0	0	16
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	15	0	0	15
activating transcription factor 6	7	0	0	7
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	8	0	0	8
v-jun sarcoma virus 17 oncogene homolog (avian)	11	0	0	11
Caspase-7	1	0	0	1
Bloom syndrome protein isoform 1	9	0	0	9
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	14	0	0	14
phospholipase A2 precursor	0	1	0	1
vitamin D3 receptor isoform VDRA	11	0	0	11
caspase-3	1	0	0	1
heat shock protein beta-1	9	0	0	9
importin subunit beta-1 isoform 1	5	0	0	5
snurportin-1	5	0	0	5
nuclear factor erythroid 2-related factor 2 isoform 1	16	0	0	16
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	8	0	0	8
DNA polymerase eta isoform 1	6	0	0	6
cysteine protease ATG4B isoform a	0	1	0	1
lethal(3)malignant brain tumor-like protein 1 isoform I	2	0	0	2
DNA polymerase kappa isoform 1	13	0	0	13
histone acetyltransferase KAT2A isoform 1	10	0	0	10
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	3	2	0	5
DNA dC->dU-editing enzyme APOBEC-3F isoform a	3	0	0	3
lamin isoform A-delta10	17	0	0	17
Free fatty acid receptor 1	0	0	2	2
Polyunsaturated fatty acid lipoxygenase ALOX15B	7	1	0	8
Prostaglandin G/H synthase 1	0	3	0	3
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
Trypsin	0	2	0	2
Cellular tumor antigen p53	18	0	0	18
Coagulation factor VII	0	2	0	2
Aromatase	0	6	0	6
Tissue factor	0	3	0	3
Peroxisome proliferator-activated receptor gamma	0	0	3	3
Histamine H2 receptor	8	0	0	8
Prostaglandin G/H synthase 2	0	4	0	4
Free fatty acid receptor 4	0	0	2	2
Chain A, Ferritin light chain	9	0	0	9
acid sphingomyelinase	4	0	0	4
cytochrome P450 family 3 subfamily A polypeptide 4	15	0	0	15
G	9	0	0	9
cytochrome P450 2D6	12	0	0	12
NEDD8-activating enzyme E1 regulatory subunit isoform a	0	1	0	1
NEDD8-conjugating enzyme Ubc12	0	1	0	1
nuclear receptor ROR-gamma isoform 1	9	0	0	9
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	0	3
Potassium channel subfamily K member 2	0	1	3	4
Interferon beta	11	0	0	11
HLA class I histocompatibility antigen, B alpha chain	9	0	0	9
ATP-dependent translocase ABCB1	0	7	1	10
Alpha-2A adrenergic receptor	0	5	2	7
Alpha-2C adrenergic receptor	0	5	1	6
Alpha-2B adrenergic receptor	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1C	0	6	0	6
Alpha-2C adrenergic receptor	0	3	0	3
Alpha-2A adrenergic receptor	0	3	0	3
Alpha-1D adrenergic receptor	0	4	0	4
Alpha-1A adrenergic receptor	0	1	0	1
Alpha-1B adrenergic receptor	0	1	0	1
5-hydroxytryptamine receptor 6	0	6	0	6
Spike glycoprotein	8	0	1	9
Sodium-dependent dopamine transporter	0	6	0	6
Voltage-dependent L-type calcium channel subunit alpha-1C	0	5	0	6
Potassium channel subfamily K member 2	0	2	0	2
Inositol hexakisphosphate kinase 1	9	0	0	9
cytochrome P450 2C9, partial	9	0	0	9
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
apical membrane antigen 1, AMA1	4	0	0	4
Beta-lactamase	0	0	0	1
urokinase-type plasminogen activator precursor	5	0	0	5
plasminogen precursor	5	0	0	5
urokinase plasminogen activator surface receptor precursor	5	0	0	5
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase	0	0	0	1
Kappa-type opioid receptor	0	3	0	4
Solute carrier family 15 member 1	0	1	0	1
Solute carrier family 15 member 1	0	1	0	1
B2 metallo-beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
NFKB1 protein, partial	3	0	0	3
alpha-galactosidase	3	0	0	3
cytochrome P450 2C19 precursor	5	0	0	5
muscarinic acetylcholine receptor M1	9	0	0	9
lethal factor (plasmid)	5	0	0	5
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, inducible	0	2	0	3
Nitric oxide synthase, inducible	0	0	1	3
Cationic amino acid transporter 3	0	2	0	2
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
interleukin 8	4	0	0	4
hypothetical protein, conserved	3	0	0	3
glucocerebrosidase	6	0	0	6
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
Prostaglandin-H2 D-isomerase	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Epidermal growth factor receptor	0	2	0	2
Fatty acid-binding protein, liver	0	2	0	2
Integrin beta-3	7	1	0	8
Myeloperoxidase	0	5	0	5
Seed linoleate 13S-lipoxygenase-1	0	3	0	5
Integrin alpha-IIb	7	1	0	8
Glutathione hydrolase 1 proenzyme	0	1	0	1
Adenosine receptor A1	0	5	0	6
Adenosine receptor A2a	0	6	0	8
Substance-P receptor	0	3	0	3
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Ras-related protein Rab-2A	0	0	1	1
Rho-associated protein kinase 2	0	1	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Solute carrier family 22 member 20	0	2	0	2
Solute carrier family 22 member 6	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	4	1	5
Sigma non-opioid intracellular receptor 1	0	2	1	3
Chain A, Putative fructose-1,6-bisphosphate aldolase	6	0	0	6
caspase-1 isoform alpha precursor	3	0	0	3
Caspase-7	3	0	0	3
Inositol monophosphatase 1	7	0	0	7
Solute carrier organic anion transporter family member 1B3	0	2	0	4
Solute carrier organic anion transporter family member 1B1	0	3	0	5
Chain A, Estrogen-related receptor gamma	0	0	1	1
Chain A, Estrogen-related receptor gamma	0	0	1	1
Chain A, Estrogen-related receptor gamma	0	0	1	1
Chain A, Estrogen-related receptor gamma	0	0	1	1
acetylcholinesterase	7	0	0	7
GALC protein	1	0	0	1
caspase 7, apoptosis-related cysteine protease	6	0	0	6
caspase-3	6	0	0	6
Histone H2A.x	6	0	0	6
thyroid hormone receptor beta isoform a	8	0	0	8
potassium voltage-gated channel subfamily H member 2 isoform d	8	0	0	8
GTP-binding nuclear protein Ran isoform 1	3	0	0	3
GTPase KRas	0	0	1	1
Estrogen receptor	0	3	1	4
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	4	0	4
Aldo-keto reductase family 1 member B1	0	7	0	7
Androgen receptor	0	2	0	2
Androgen receptor	0	2	0	2
Sodium-dependent noradrenaline transporter	0	8	1	9
Sodium-dependent serotonin transporter	0	5	0	5
Estrogen-related receptor gamma	0	1	0	1
GTP-binding protein Rheb	0	0	1	1
Estrogen receptor beta	0	1	1	2
Chain A, Glycogen Phosphorylase	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Chitinase	0	1	0	1
atrial natriuretic peptide receptor 1 precursor	2	0	0	2
DNA polymerase beta	7	0	0	7
Glycogen phosphorylase, muscle form	0	1	0	1
Renin	0	1	0	1
Cholinesterase	0	4	0	4
Glycogen phosphorylase, liver form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Replicase polyprotein 1ab	0	5	2	7
Adenosine receptor A3	0	6	0	6
Replicase polyprotein 1ab	0	5	2	7
Amine oxidase [flavin-containing] A	0	5	0	5
Acetylcholinesterase	0	6	0	6
Amine oxidase [flavin-containing] B	0	6	0	6
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	2	0	2
Adenosine receptor A3	0	2	0	2
Adenosine receptor A2a	0	3	1	5
Adenosine receptor A2b	0	1	0	2
Adenosine receptor A2b	0	2	0	3
Adenosine receptor A1	0	3	1	6
Vasopressin V2 receptor	0	0	0	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Adenosine receptor A2a	0	1	0	1
Adenosine receptor A1	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	2	0	2
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	2	0	2
Adenylate cyclase type 1	0	0	0	1
Chitotriosidase-1	0	1	0	1
Serine-protein kinase ATM	0	1	0	1
Serine/threonine-protein kinase ATR	0	1	0	1
Adenosine receptor A2b	0	1	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	2	0	2
Palmitoleoyl-protein carboxylesterase NOTUM	0	2	2	4
Endochitinase B1	0	1	0	1
Muscarinic acetylcholine receptor	0	0	0	1
Phosphodiesterase	0	2	0	2
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	5	1	7
Guanine deaminase	0	1	0	1
67.9K protein	8	0	0	8
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	5	0	0	5
thyrotropin-releasing hormone receptor	2	0	0	2
mitogen-activated protein kinase 1	8	0	0	8
survival motor neuron protein isoform d	8	0	0	8
Caspase-2	0	0	1	1
ATPase family AAA domain-containing protein 5	8	0	0	8
Ataxin-2	9	0	0	9
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein	0	0	1	1
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Choline-binding protein	0	0	1	1
Solute carrier family 22 member 1	0	1	0	2
Solute carrier family 22 member 2	0	1	0	2
Solute carrier family 22 member 1	0	2	0	3
Solute carrier family 22 member 2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-3	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	0	3	0	3
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	0	3	0	3
Neuronal acetylcholine receptor subunit beta-3	0	1	0	1
Neuronal acetylcholine receptor subunit beta-4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-5	0	1	0	1
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Choline O-acetyltransferase	0	1	0	2
Neuronal acetylcholine receptor subunit alpha-6	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-9	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	2	0	2
Solute carrier family 22 member 1	0	1	0	3
High affinity choline transporter 1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-10	0	1	0	1
Solute carrier family 22 member 2	0	1	0	2
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain H, Fab M82G2, Heavy chain	0	0	1	1
Chain L, Fab M82G2, Light chain	0	0	1	1
Chain H, Fab M82g2, Heavy Chain	0	0	1	1
Chain L, Fab M82g2, Light Chain	0	0	1	1
Gamma-aminobutyric acid receptor subunit pi	0	3	0	3
Gamma-aminobutyric acid receptor subunit delta	0	3	0	3
Amyloid-beta precursor protein	0	5	1	7
Fatty acid-binding protein, heart	0	3	0	3
Muscarinic acetylcholine receptor M2	0	1	0	1
Muscarinic acetylcholine receptor M1	0	3	1	4
5-hydroxytryptamine receptor 2C	0	4	0	5
Tryptophan 5-hydroxylase 1	0	1	0	1
5-hydroxytryptamine receptor 2A	0	7	0	7
Gamma-aminobutyric acid receptor subunit alpha-1	0	3	2	5
Gamma-aminobutyric acid receptor subunit beta-1	0	3	0	3
Gamma-aminobutyric acid receptor subunit gamma-2	0	3	1	4
D	0	2	0	2
5-hydroxytryptamine receptor 1A	0	7	1	9
Liver carboxylesterase 1	0	0	0	1
Sodium-dependent dopamine transporter	0	3	0	3
Gamma-aminobutyric acid receptor subunit beta-3	0	3	1	4
5-hydroxytryptamine receptor 1B	0	3	0	3
5-hydroxytryptamine receptor 1D	0	1	0	1
5-hydroxytryptamine receptor 1F	0	1	0	1
5-hydroxytryptamine receptor 2B	0	3	0	3
5-hydroxytryptamine receptor 6	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	3	2	5
Sodium-dependent serotonin transporter	0	5	0	6
5-hydroxytryptamine receptor 7	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	3	1	4
5-hydroxytryptamine receptor 5A	0	1	0	1
5-hydroxytryptamine receptor 5B	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	3	0	4
5-hydroxytryptamine receptor 3A	0	1	0	1
Lysosomal Pro-X carboxypeptidase	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	3	1	4
Gamma-aminobutyric acid receptor subunit beta-2	0	3	1	4
Gamma-aminobutyric acid receptor subunit alpha-4	0	3	0	3
D(2) dopamine receptor	0	3	0	3
Gamma-aminobutyric acid receptor subunit epsilon	0	3	0	3
Glutamate receptor ionotropic, NMDA 2A	0	3	0	4
Glutamate receptor ionotropic, NMDA 2B	0	3	0	4
Glutamate receptor ionotropic, NMDA 2C	0	3	0	5
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	6	0	6
Leukotriene B4 receptor 1	0	1	0	2
Gamma-aminobutyric acid receptor subunit alpha-6	0	3	0	3
Sodium-dependent dopamine transporter	0	2	0	2
Glutamate receptor ionotropic, NMDA 2D	0	3	0	4
5-hydroxytryptamine receptor 4	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	3	0	3
Glutamate receptor ionotropic, NMDA 3B	0	3	0	4
Gamma-aminobutyric acid receptor subunit gamma-3	0	3	0	3
5-hydroxytryptamine receptor 3B	0	1	0	1
Leukotriene B4 receptor 2	0	1	0	2
Glutamate receptor ionotropic, NMDA 3A	0	3	0	4
Gamma-aminobutyric acid receptor subunit theta	0	3	0	3
Transporter	0	3	0	3
Chain A, Breast cancer type 1 susceptibility protein	1	0	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	4	0	0	4
Nrf2	2	0	0	2
pregnane X receptor	3	0	0	3
alkaline phosphatase, intestinal	0	1	1	2
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	5	0	0	5
PINK1	2	0	0	2
Parkin	6	0	0	6
bromodomain adjacent to zinc finger domain 2B	6	0	0	6
toll-like receptor 9	0	1	0	1
TPA: protein transporter TIM10	0	1	0	1
lysosomal alpha-glucosidase preproprotein	4	0	0	4
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein	0	1	1	2
hemoglobin subunit beta	1	0	0	1
cellular tumor antigen p53 isoform a	10	0	0	10
polyunsaturated fatty acid lipoxygenase ALOX12	4	0	0	4
perilipin-5	0	2	0	2
intestinal alkaline phosphatase precursor	0	1	1	2
perilipin-1	0	2	0	2
transcriptional regulator ERG isoform 3	2	0	0	2
huntingtin isoform 2	3	0	0	3
pyruvate kinase PKM isoform a	1	0	0	1
nuclear factor NF-kappa-B p105 subunit isoform 1	1	0	1	2
histone-lysine N-methyltransferase 2A isoform 2 precursor	4	0	0	4
tumor susceptibility gene 101 protein	1	0	0	1
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	2	0	2
muscleblind-like protein 1 isoform 1	6	0	0	6
alkaline phosphatase, germ cell type preproprotein	0	1	1	2
hypothetical protein SA1422	0	1	0	1
neuropeptide S receptor isoform A	3	0	0	3
Prostaglandin E synthase	0	1	0	1
Histone deacetylase 3	0	1	0	1
Acetylcholinesterase	0	3	0	3
Lysine-specific histone demethylase 1A	0	3	0	3
D-amino-acid oxidase	0	1	0	1
Phospholipase A2	0	2	0	2
Neuronal proto-oncogene tyrosine-protein kinase Src	0	1	0	1
Heme oxygenase 1	0	1	0	1
Glutathione S-transferase P	0	2	0	2
Polyunsaturated fatty acid 5-lipoxygenase	0	3	0	3
Microtubule-associated protein tau	0	1	0	2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	0	1	0	1
Tyrosinase	0	3	0	3
Aminopeptidase N	0	1	0	1
Aminopeptidase N	0	1	0	1
Alpha-1B adrenergic receptor	0	5	0	5
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	0	2	0	2
Glycogen synthase kinase-3 beta	0	2	0	2
Heme oxygenase 2	0	1	0	1
Alpha-1D adrenergic receptor	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	3	0	3
Proteasome subunit beta type-5	0	2	0	2
17-beta-hydroxysteroid dehydrogenase type 2	0	2	0	2
Alpha-synuclein	2	3	1	6
Alpha-1A adrenergic receptor	0	5	0	5
Glycogen synthase kinase-3 beta	0	2	0	2
Histone deacetylase 4	0	1	0	1
Beta-secretase 1	0	3	0	3
Guanine nucleotide-binding protein G	1	0	0	1
Cholinesterase	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1S	0	3	0	3
Lactoylglutathione lyase	0	3	0	3
Histone acetyltransferase p300	0	1	0	1
TAR DNA-binding protein 43	5	0	0	5
Serine/threonine-protein kinase PAK 1	0	2	0	2
Histone deacetylase 1	0	2	0	2
5-hydroxytryptamine receptor 4	0	0	1	1
Sodium/bile acid cotransporter	0	0	1	1
Nuclear factor erythroid 2-related factor 2	0	0	2	4
Thioredoxin reductase 1, cytoplasmic	0	1	0	1
Thioredoxin reductase 3	0	1	0	1
Sortase A	0	1	0	1
Histone deacetylase 7	0	1	0	1
Histone deacetylase 2	0	2	0	2
CREB-binding protein	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3	0	2	0	2
Cysteine protease	0	1	0	1
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 11	0	1	0	1
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
Histone deacetylase 8	0	2	0	2
Thioredoxin reductase 2, mitochondrial	0	1	0	1
CDGSH iron-sulfur domain-containing protein 1	0	2	0	2
Histone deacetylase 6	0	1	0	1
Histone deacetylase 9	0	1	0	1
Histone deacetylase 5	0	1	0	1
Lymphocyte antigen 96	0	0	1	1
Beta lactamase (plasmid)	0	1	0	1
Interferon regulatory factor 3	0	0	1	1
Stimulator of interferon genes protein	0	0	2	2
Stimulator of interferon genes protein	0	1	2	3
Fumarate hydratase	3	0	0	3
PPM1D protein	3	0	0	3
polyprotein	3	0	0	3
cytochrome P450 2D6 isoform 1	6	0	0	6
D(1A) dopamine receptor	4	0	0	4
atrial natriuretic peptide receptor 2 precursor	4	0	0	4
serine/threonine-protein kinase mTOR isoform 1	4	0	0	4
chaperonin GroEL	1	0	0	1
Sodium-dependent noradrenaline transporter	0	1	0	1
5-hydroxytryptamine receptor 4	0	4	0	4
Muscarinic acetylcholine receptor M2	0	2	0	3
Muscarinic acetylcholine receptor M4	0	2	0	3
Muscarinic acetylcholine receptor M3	0	2	1	3
Muscarinic acetylcholine receptor M4	0	2	1	3
Muscarinic acetylcholine receptor M5	0	2	1	3
Muscarinic acetylcholine receptor M5	0	2	0	3
Muscarinic acetylcholine receptor M2	0	2	1	3
Glycogen phosphorylase, brain form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Muscarinic acetylcholine receptor M1	0	2	0	3
Angiotensin-converting enzyme	0	2	0	2
D(2) dopamine receptor	0	2	0	2
Alpha-2B adrenergic receptor	0	2	0	2
D(3) dopamine receptor	0	1	0	1
Muscarinic acetylcholine receptor M3	0	2	0	3
Endothelin receptor type B	2	1	0	3
D(1A) dopamine receptor	0	2	0	2
UDP-glucuronosyltransferase 1A4	0	0	0	1
Endothelin receptor type B	0	1	0	1
Histamine H2 receptor	0	2	0	2
D(1B) dopamine receptor	0	1	0	1
5-hydroxytryptamine receptor 2A	0	2	0	2
5-hydroxytryptamine receptor 2C	0	4	0	4
D(4) dopamine receptor	0	1	0	1
5-hydroxytryptamine receptor 2C	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
Histamine H1 receptor	0	2	1	3
D(3) dopamine receptor	0	2	0	2
UDP-glucuronosyltransferase 1A3	0	0	0	2
5-hydroxytryptamine receptor 2B	0	2	0	2
D(2) dopamine receptor	0	1	0	1
Sodium-dependent serotonin transporter	0	1	0	1
Nuclear receptor subfamily 3 group C member 3	0	2	0	2
Histone-lysine N-methyltransferase SETD7	0	2	0	2
Alpha-tocopherol transfer protein	0	0	1	1
Alpha-1B adrenergic receptor	0	0	1	1
cytochrome P450 2C9 precursor	3	0	0	3
Alpha-1A adrenergic receptor	0	0	1	1
Gamma-aminobutyric acid	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	3	0	3
Alpha-1-acid glycoprotein 1	0	0	0	1
Albumin	0	0	1	2
Albumin	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	2
Translocator protein	0	1	2	4
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Translocator protein	0	1	0	1
Translocator protein	0	1	0	1
Cholecystokinin receptor type A	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1S	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Sphingosine-1-phosphate lyase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Cereblon isoform 4	0	2	0	2
Insulin-like growth factor-binding protein 5	0	0	1	1
Protein cereblon	0	4	0	4
Carbonic anhydrase	0	1	0	2
Chain A, Dihydrofolate reductase	0	0	1	1
nuclear factor erythroid 2-related factor 2 isoform 2	4	0	0	4
Thymidylate synthase	0	4	0	4
Thymidylate synthase	0	3	0	3
Dihydrofolate reductase	0	2	3	5
Aldo-keto reductase family 1 member B1	0	2	0	2
Folylpolyglutamate synthase, mitochondrial	0	1	0	4
Solute carrier organic anion transporter family member 1A3	0	1	0	3
Folylpolyglutamate synthase, mitochondrial	0	1	0	4
Multidrug resistance associated protein	0	1	0	3
Chain E, Fibrin beta chain	0	1	0	1
Chain A, RNA-directed RNA polymerase NS5	0	1	0	1
Mcl-1	0	1	0	1
MPI protein	0	1	0	1
Cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0	0	0	1
luciferase	1	0	0	1
pyruvate kinase	2	0	0	2
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	1	0	1
CDK5	0	0	0	1
serine-protein kinase ATM isoform a	1	0	0	1
major prion protein preproprotein Prp precursor	0	1	0	1
glucose-6-phosphate 1-dehydrogenase isoform b	0	1	0	1
Vif	0	2	0	2
Tat	0	1	0	1
endoribonuclease toxin MazF	0	0	1	1
Pyruvate kinase PKM	0	1	0	1
Endothelin-1 receptor	2	0	0	2
phosphoglycerate kinase	2	0	0	2
hypothetical protein CAALFM_CR05890CA	0	0	0	1
H3 histone acetyltransferase	0	0	0	1
large T antigen	0	2	0	2
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	1	0	1
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
N-glycosylase/DNA lyase	0	1	0	1
Polyphenol oxidase 2	0	3	0	4
Formamidopyrimidine-DNA glycosylase	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	1
Cytochrome P450 2C8	0	2	0	2
Cytochrome P450 2A6	0	1	0	1
Macrophage migration inhibitory factor	0	1	0	1
Cytochrome P450 2C19	0	2	0	2
Endonuclease III-like protein 1	0	1	0	1
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	2
Pantothenate synthetase	0	1	0	1
Isocitrate lyase	0	1	0	1
Putative FAD-containing monooxygenase MymA	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Endonuclease 8-like 1	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, Leucine Aminopeptidase	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	2	0	2
Intestinal-type alkaline phosphatase	0	2	0	2
Large neutral amino acids transporter small subunit 1	0	2	0	2
Proton-coupled amino acid transporter 1	0	1	0	2
Phospholipase A-2-activating protein	0	2	0	2
Sterol O-acyltransferase 1	0	1	0	1
Fatty acid-binding protein, adipocyte	0	2	0	2
Tyrosine-protein phosphatase non-receptor type 7	0	1	0	1
Sterol O-acyltransferase 1	0	1	0	1
Aldo-keto reductase family 1 member C3	0	1	0	1
Nuclear receptor subfamily 4 group A member 2	0	0	2	2
Dual specificity protein phosphatase 3	0	1	0	1
Fatty acid-binding protein 5	0	1	0	1
Peroxisome proliferator-activated receptor alpha	1	0	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Glutathione reductase, mitochondrial	0	5	0	5
ClpP	3	0	0	3
peripheral myelin protein 22 isoform 1	5	0	0	5
ras-related protein Rab-9A	3	0	0	3
M-phase phosphoprotein 8	8	0	0	8
Cytochrome P450 1A2	0	1	0	1
Cytochrome P450 2C11	0	1	0	1
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	4	1	5
Metabotropic glutamate receptor 1	0	1	0	1
Acetylcholinesterase	0	1	0	1
Mu-type opioid receptor	0	4	1	8
Nociceptin receptor	0	1	0	1
Melatonin receptor type 1A	0	2	1	3
Melatonin receptor type 1C	0	0	1	1
Melatonin receptor type 1A	0	1	1	2
Melatonin receptor type 1B	0	2	1	3
Melatonin receptor type 1C	0	1	1	2
Melatonin receptor type 1B	0	1	1	2
Cytochrome P450 1B1	0	5	1	6
Carboxylic ester hydrolase	0	1	0	1
Histamine H3 receptor	0	1	0	1
Dihydrofolate reductase	0	5	0	6
Dipeptidyl peptidase 4	0	3	0	3
Multidrug and toxin extrusion protein 1	0	1	0	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
dopamine D1 receptor	1	0	0	1
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	1	0	1
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	1	0	1
transactivating tegument protein VP16 [Human herpesvirus 1]	0	2	0	2
nuclear receptor coactivator 3 isoform a	0	1	0	1
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	3
Thymidylate synthase	0	1	0	1
Tyrosine-protein kinase ABL1	0	1	1	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
High mobility group protein B1	0	0	1	1
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Folate receptor beta	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Histidine decarboxylase	0	1	1	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Cyclin-dependent kinase 2	0	1	1	2
Bifunctional purine biosynthesis protein ATIC	0	2	0	2
Multidrug resistance-associated protein 1	0	1	0	2
Kappa-type opioid receptor	0	3	1	5
Reduced folate transporter	0	2	0	2
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Pteridine reductase 1	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Solute carrier family 22 member 6	0	0	0	2
Canalicular multispecific organic anion transporter 1	0	1	0	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Solute carrier family 22 member 8	0	0	0	2
Dihydrofolate reductase	0	1	0	1
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Solute carrier family 22 member 11	0	0	0	1
Protein-arginine deiminase type-4	0	1	0	1
Opioid receptor, delta 1b	0	1	0	1
Opioid receptor homologue	0	1	0	1
ATP-dependent translocase ABCB1	0	2	0	2
Acyl-CoA desaturase 1	0	1	0	1
ATP-dependent translocase ABCB1	0	2	0	2
Proteinase-activated receptor 1	0	1	1	2
Delta-type opioid receptor	0	1	0	3
Kappa-type opioid receptor	0	2	1	5
Mu-type opioid receptor	0	2	1	4
Delta-type opioid receptor	0	2	1	4
Kappa-type opioid receptor	0	2	1	4
Mu-type opioid receptor	0	2	1	6
Nociceptin receptor	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	2	0	2
Mas-related G-protein coupled receptor member X2	0	0	1	1
Mu-type opioid receptor	0	1	0	1
NPC intracellular cholesterol transporter 1 precursor	2	0	0	2
Equilibrative nucleoside transporter 1	0	1	0	1
B2 bradykinin receptor	0	2	0	2
Chymotrypsinogen A	0	2	0	2
Beta-lactamase	0	2	0	2
Quinolone resistance protein NorA	0	1	0	1
Malate dehydrogenase, cytoplasmic	0	1	0	1
D(1A) dopamine receptor	2	0	0	2
Transient receptor potential cation channel subfamily A member 1	0	0	2	2
Thrombopoietin	1	0	0	1
nonstructural protein 1	1	0	0	1
beta-2 adrenergic receptor	1	0	0	1
tumor necrosis factor	1	0	0	1
eyes absent homolog 2 isoform a	1	0	0	1
Phospholipase A2, membrane associated	0	0	0	1
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	1	0	1
Thromboxane-A synthase	0	1	0	1
Platelet-activating factor receptor	0	0	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	1	0	1
C-C chemokine receptor type 2	0	2	0	2
Sodium channel protein type 7 subunit alpha	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Potassium voltage-gated channel subfamily A member 1	0	1	0	1
C-terminal-binding protein 1	1	0	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Sodium channel protein type 5 subunit alpha	0	2	0	2
Myosin light chain kinase, smooth muscle	0	1	0	1
Sodium channel protein type 9 subunit alpha	0	1	0	1
Indoleamine 2,3-dioxygenase 2	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Sodium channel protein type 11 subunit alpha	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	1	0	1
Sodium channel protein type 10 subunit alpha	0	1	0	1
Chain A, Immunoglobulin	0	0	1	1
Chain B, Immunoglobulin	0	0	1	1
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Muscarinic acetylcholine receptor M1	0	0	1	2
Cytochrome P450 2B6	0	1	0	1
Muscarinic acetylcholine receptor M4	0	0	1	2
Cholinesterase	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 2A	0	2	0	2
Glutamate receptor ionotropic, NMDA 2B	0	2	0	2
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Muscarinic acetylcholine receptor M5	0	0	1	2
Muscarinic acetylcholine receptor M3	0	0	1	2
Muscarinic acetylcholine receptor M2	0	0	1	2
Chain D, PROTEIN (PHOSPHOGLYCERATE MUTASE 1)	0	1	0	1
Chain A, PROTEIN (PHOSPHOGLYCERATE MUTASE 1)	0	1	0	1
Chain A, Beta-arrestin 1	0	0	1	1
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b	0	0	1	1
nuclear receptor subfamily 1, group I, member 2	2	0	0	2
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, APH(2')-Id	0	1	0	1
glucose-6-phosphate dehydrogenase	0	1	0	1
signal transducer and activator of transcription 6, interleukin-4 induced	1	0	0	1
DNA polymerase III, partial	1	0	0	1
Neuraminidase	0	2	0	2
hexokinase	0	1	0	1
Spike glycoprotein	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
galactokinase	1	0	0	1
interferon gamma precursor	0	0	0	1
histone deacetylase 9 isoform 3	2	0	0	2
ubiquitin carboxyl-terminal hydrolase 2 isoform a	2	0	0	2
tyrosine-protein kinase Yes	1	0	0	1
Transmembrane protease serine 2	0	0	1	1
Maltase-glucoamylase, intestinal	0	1	0	1
NUAK family SNF1-like kinase 1	0	1	0	1
G2/mitotic-specific cyclin-B2	0	1	0	1
Arginase	0	1	0	1
Pancreatic triacylglycerol lipase	0	1	0	1
Prothrombin	0	1	1	2
Prothrombin	0	1	0	1
Urokinase-type plasminogen activator	0	1	0	1
Cationic trypsin	0	1	0	1
Chymotrypsin-like elastase family member 1	0	1	0	1
Protein E6	0	1	0	1
Neuraminidase	0	1	0	1
Interstitial collagenase	0	1	1	2
Beta-lactamase	0	1	0	1
Tyrosine-protein kinase Lck	0	2	0	2
Cyclin-dependent kinase 1	0	1	0	1
Glycogen phosphorylase, liver form	0	1	0	1
Epoxide hydrolase 1	0	1	0	1
Trypsin-1	0	1	0	1
Trypsin-2	0	1	0	1
Procathepsin L	0	0	1	1
Tyrosine-protein kinase Yes	0	1	0	1
Proto-oncogene tyrosine-protein kinase receptor Ret	0	1	0	1
Insulin-like growth factor 1 receptor	0	1	0	1
Neutrophil elastase	0	2	0	2
72 kDa type IV collagenase	0	1	0	1
Stromelysin-1	0	2	0	2
Hepatocyte growth factor receptor	0	1	0	1
5-hydroxytryptamine receptor 1A	0	0	1	1
Heterogeneous nuclear ribonucleoprotein A1	0	0	1	1
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	0	1	0	1
Replicase polyprotein 1a	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Calmodulin-1	0	1	0	1
Alpha-amylase 1A	0	1	0	1
Lysosomal alpha-glucosidase	0	1	0	1
Sialidase	0	1	0	1
Malate dehydrogenase	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 2	0	1	0	1
Serine/threonine-protein kinase pim-1	0	1	1	2
Cyclin-dependent kinase 4	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	1	0	1
Cystic fibrosis transmembrane conductance regulator	0	0	1	1
Sucrase-isomaltase, intestinal	0	1	0	1
G2/mitotic-specific cyclin-B1	0	1	0	1
Matrix metalloproteinase-9	0	1	0	1
Urease subunit alpha	0	2	0	2
Serine/threonine-protein kinase B-raf	0	1	0	1
G2/mitotic-specific cyclin-B	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Chymotrypsinogen B	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	2	0	2
Polyunsaturated fatty acid lipoxygenase ALOX12	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 4	0	1	0	1
Casein kinase II subunit alpha'	0	2	0	2
Amine oxidase [flavin-containing] A	0	1	0	1
5'-nucleotidase	0	1	0	1
D(4) dopamine receptor	0	1	0	1
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
G1/S-specific cyclin-D1	0	1	0	1
C-X-C chemokine receptor type 1	0	1	0	1
Phosphatidylinositol 3-kinase regulatory subunit alpha	0	1	0	1
Cytosol aminopeptidase	0	1	0	1
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	0	2	0	2
Vasopressin V2 receptor	0	1	0	1
Tyrosine-protein kinase receptor UFO	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
RAC-alpha serine/threonine-protein kinase	0	1	0	1
Bifunctional epoxide hydrolase 2	0	1	0	1
Trypsin-3	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Vascular endothelial growth factor receptor 2	0	1	0	1
Receptor-type tyrosine-protein kinase FLT3	0	1	0	1
Macrophage metalloelastase	0	1	0	1
Glutathione reductase	0	1	0	1
Tyrosine-protein kinase SYK	0	1	1	2
Collagenase 3	0	1	0	1
1-deoxy-D-xylulose 5-phosphate reductoisomerase	0	1	0	1
Xanthine dehydrogenase/oxidase	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Prolyl endopeptidase	0	1	0	1
Glycogen synthase kinase-3 alpha	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
C-C chemokine receptor type 4	0	1	0	1
Serine/threonine-protein kinase Nek2	0	1	0	1
Oligo-1,6-glucosidase IMA1	0	1	0	1
Serine/threonine-protein kinase PLK1	0	1	0	1
Death-associated protein kinase 1	0	1	0	1
Mitogen-activated protein kinase 10	0	1	0	1
Monocarboxylate transporter 1	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Anthrax toxin receptor 2	0	1	0	1
Casein kinase II subunit beta	0	2	0	2
Casein kinase II subunit alpha	0	2	0	2
Urease subunit beta	0	2	0	2
Disintegrin and metalloproteinase domain-containing protein 17	2	0	0	2
Lactoperoxidase	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Xanthine dehydrogenase/oxidase	0	2	0	3
Cyclin-dependent kinase 6	0	1	0	1
Cyclin-dependent-like kinase 5	0	1	0	1
Heat shock factor protein 1	0	1	0	1
Sorbitol dehydrogenase	0	1	0	1
Cyclin homolog	0	1	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Dual specificity mitogen-activated protein kinase kinase 1	0	1	0	1
Focal adhesion kinase 1	0	1	0	1
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	1	0	1
ELAV-like protein 3	0	1	0	1
Cyclin-dependent kinase 5 activator 1	0	1	0	1
ELAV-like protein 1	0	1	0	1
Serine/threonine-protein kinase N1	0	1	0	1
Mitogen-activated protein kinase 14	0	1	0	1
Probable maltase-glucoamylase 2	0	1	0	1
Carbonic anhydrase 3	0	1	0	1
Monocarboxylate transporter 2	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Substance-K receptor	0	1	0	1
Integrase	0	1	0	1
Casein kinase II subunit alpha 3	0	2	0	2
Inositol polyphosphate multikinase	0	1	0	1
G2/mitotic-specific cyclin-B3	0	1	0	1
Aldo-keto reductase family 1 member C21	0	2	0	2
Enoyl-acyl-carrier protein reductase	0	2	0	2
3-oxoacyl-acyl-carrier protein reductase	0	1	0	1
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)	0	1	0	1
Aurora kinase B	0	1	0	1
Chymotrypsin-C	0	1	0	1
Angiotensin-converting enzyme 2	0	0	1	1
Cyclin-dependent kinase 1	0	1	0	1
G-protein coupled receptor 35	0	1	1	2
Serine/threonine-protein kinase Nek6	0	1	0	1
NADPH oxidase 4	0	1	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	1	0	1
Dipeptidyl peptidase 3	0	1	0	1
Inositol hexakisphosphate kinase 2	0	1	0	1
Short transient receptor potential channel 5	0	1	0	1
ALK tyrosine kinase receptor	0	1	0	1
Sialidase-2	0	1	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	3	0	0	3
Voltage-gated sodium channel Nav1.5 cardiac isoform	0	1	0	1
Chain A, Troponin C, slow skeletal and cardiac muscles	0	0	1	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
BRCA1	1	0	0	1
P53	1	0	0	1
M18 aspartyl aminopeptidase	0	1	0	1
cathepsin L1	0	1	0	1
hexokinase-4 isoform 1	1	0	0	1
glucokinase regulatory protein	1	0	0	1
FAD-linked sulfhydryl oxidase ALR	0	0	0	1
transcription factor p65 isoform 1	0	0	1	1
serine/threonine-protein kinase 33 isoform a	0	0	1	1
POsterior Segregation	0	0	1	1
Aryl hydrocarbon receptor	0	1	0	1
Estrogen receptor beta	0	0	1	1
Transient receptor potential cation channel subfamily A member 1	0	1	1	2
Myc proto-oncogene protein	0	1	0	2
Transthyretin	0	1	1	3
Cathepsin D	0	1	0	1
Luciferin 4-monooxygenase	0	1	0	1
DNA polymerase alpha catalytic subunit	0	1	0	1
Leukotriene A-4 hydrolase	0	1	0	1
Breakpoint cluster region protein	0	1	0	2
Tyrosinase	0	2	0	2
Ornithine decarboxylase	0	1	0	1
Protein kinase C alpha type	0	0	1	1
Estrogen receptor	0	0	1	1
Nuclear factor NF-kappa-B p105 subunit	0	1	0	1
Sucrase-isomaltase, intestinal	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
Alpha-glucosidase MAL12	0	1	0	1
Nuclear factor NF-kappa-B p100 subunit	0	1	0	1
Squalene synthase	0	1	0	1
Transcription factor p65	0	1	0	1
Bcl-2-like protein 1	0	1	0	1
N1L	0	1	0	1
NAD(P)H dehydrogenase [quinone] 1	0	0	0	2
Tubulin beta-2B chain	0	1	0	1
Lysosomal alpha-glucosidase	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-2	0	0	1	1
Carbonic anhydrase 13	0	1	0	1
Rap guanine nucleotide exchange factor 4	1	0	0	1
NAD-dependent protein deacetylase sirtuin-1	0	0	1	3
Prenyltransferase homolog	0	0	0	1
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	0	1	1
Zinc finger protein mex-5	0	0	1	1
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR	0	0	1	1
Retinol-binding protein 4	0	0	1	1
Beta-lactoglobulin	0	0	1	1
Sphingosine kinase 2	0	2	0	2
Sphingosine kinase 1	0	1	0	1
photoreceptor-specific nuclear receptor	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	2	0	2
Insulin receptor	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	1	0	1
Adenylate kinase isoenzyme 1	0	0	0	1
Adenylate kinase 2, mitochondrial	0	0	0	1
Capsid protein	0	0	1	1
Reverse transcriptase/RNaseH	0	1	1	4
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Solute carrier organic anion transporter family member 1A4	0	0	0	1
Solute carrier organic anion transporter family member 1A5	0	0	0	1
Thyroid hormone receptor alpha	0	0	1	1
Thyroid hormone receptor beta	0	0	1	1
Proliferating cell nuclear antigen	0	1	0	1
Retinoic acid receptor RXR-alpha	0	0	2	2
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	0	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	1
Monocarboxylate transporter 8	0	0	0	1
Bile acid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
HLA class I histocompatibility antigen, A alpha chain	0	0	1	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
Plasma kallikrein	0	0	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	2
Tryptophan 2,3-dioxygenase	0	1	0	2
Carbonic anhydrase	0	0	0	1
SLC16A10 protein	0	0	0	1
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase-like protein, putative	0	0	0	1
Tryprostatin B synthase	0	0	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Carbonic anhydrase	0	0	0	1
Monocarboxylate transporter 10	0	0	0	1
Chain A, Uracil-DNA Glycosylase	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Non-communicable Chronic Diseases

Synonyms(5)

Research Excerpts

Treatment

Research

Studies (280)

Protein Targets (1,124)

Non-communicable Chronic Diseases

Synonyms(5)

Research Excerpts

Treatment

Research

Studies (280)

Drugs Studied (107)

Protein Targets (1,124)