| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| estrogen nuclear receptor alpha | 5 | 0 | 0 | 5 |
| thyroid hormone receptor beta isoform 2 | 3 | 0 | 0 | 3 |
| Steroid 17-alpha-hydroxylase/17,20 lyase | 0 | 1 | 0 | 1 |
| Cytochrome P450 3A4 | 0 | 2 | 2 | 4 |
| Androgen receptor | 0 | 0 | 1 | 1 |
| Chain A, Beta-lactamase | 1 | 0 | 0 | 1 |
| acetylcholinesterase | 2 | 0 | 0 | 2 |
| USP1 protein, partial | 1 | 0 | 0 | 1 |
| GLS protein | 2 | 0 | 0 | 2 |
| glucocorticoid receptor [Homo sapiens] | 4 | 0 | 0 | 4 |
| cytochrome P450 2D6 | 4 | 0 | 0 | 4 |
| peroxisome proliferator-activated receptor delta | 3 | 0 | 0 | 3 |
| aryl hydrocarbon receptor | 2 | 0 | 0 | 2 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | 1 | 0 | 0 | 1 |
| cytochrome P450 2D6 isoform 1 | 2 | 0 | 0 | 2 |
| potassium voltage-gated channel subfamily H member 2 isoform d | 2 | 0 | 0 | 2 |
| peripheral myelin protein 22 | 1 | 0 | 0 | 1 |
| ATP-binding cassette sub-family C member 3 | 0 | 4 | 0 | 4 |
| Multidrug resistance-associated protein 4 | 0 | 4 | 0 | 4 |
| Bile salt export pump | 0 | 6 | 0 | 6 |
| Canalicular multispecific organic anion transporter 1 | 0 | 4 | 0 | 4 |
| Luciferase | 2 | 0 | 0 | 2 |
| TDP1 protein | 4 | 0 | 0 | 4 |
| AR protein | 3 | 0 | 0 | 3 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 1 | 0 | 0 | 1 |
| pregnane X nuclear receptor | 2 | 0 | 0 | 2 |
| euchromatic histone-lysine N-methyltransferase 2 | 3 | 0 | 0 | 3 |
| Solute carrier family 22 member 1 | 0 | 7 | 0 | 8 |
| Nuclear receptor subfamily 1 group I member 2 | 0 | 0 | 1 | 1 |
| ATP-dependent translocase ABCB1 | 0 | 2 | 0 | 3 |
| D(2) dopamine receptor | 0 | 5 | 0 | 5 |
| Amine oxidase [flavin-containing] A | 0 | 1 | 0 | 1 |
| D(4) dopamine receptor | 0 | 3 | 0 | 3 |
| Amine oxidase [flavin-containing] B | 0 | 1 | 0 | 1 |
| Delta-type opioid receptor | 0 | 7 | 2 | 12 |
| Delta-type opioid receptor | 0 | 9 | 4 | 14 |
| Mu-type opioid receptor | 0 | 9 | 5 | 17 |
| Kappa-type opioid receptor | 0 | 7 | 4 | 12 |
| Histamine H1 receptor | 0 | 3 | 1 | 4 |
| Mu-type opioid receptor | 0 | 11 | 8 | 23 |
| D(3) dopamine receptor | 0 | 5 | 0 | 5 |
| Delta-type opioid receptor | 0 | 10 | 6 | 20 |
| Kappa-type opioid receptor | 0 | 10 | 1 | 12 |
| Kappa-type opioid receptor | 0 | 10 | 6 | 21 |
| Mu-type opioid receptor | 0 | 6 | 3 | 13 |
| Mu-type opioid receptor | 0 | 8 | 2 | 11 |
| Potassium voltage-gated channel subfamily H member 2 | 0 | 5 | 0 | 5 |
| Sigma non-opioid intracellular receptor 1 | 0 | 4 | 0 | 4 |
| Sigma non-opioid intracellular receptor 1 | 0 | 5 | 0 | 5 |
| Sigma non-opioid intracellular receptor 1 | 0 | 2 | 0 | 2 |
| Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E | 0 | 0 | 1 | 1 |
| GLI family zinc finger 3 | 2 | 0 | 0 | 2 |
| aldehyde dehydrogenase 1 family, member A1 | 2 | 0 | 0 | 2 |
| retinoic acid nuclear receptor alpha variant 1 | 2 | 0 | 0 | 2 |
| retinoid X nuclear receptor alpha | 1 | 0 | 0 | 1 |
| activating transcription factor 6 | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform a | 1 | 0 | 0 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 2 | 0 | 0 | 2 |
| lamin isoform A-delta10 | 3 | 0 | 0 | 3 |
| Cellular tumor antigen p53 | 3 | 0 | 0 | 3 |
| thioredoxin reductase | 1 | 0 | 0 | 1 |
| EWS/FLI fusion protein | 1 | 0 | 0 | 1 |
| NPC intracellular cholesterol transporter 1 precursor | 1 | 0 | 0 | 1 |
| chromobox protein homolog 1 | 1 | 0 | 0 | 1 |
| ras-related protein Rab-9A | 1 | 0 | 0 | 1 |
| Fatty acid-binding protein, liver | 0 | 1 | 0 | 1 |
| Albumin | 0 | 1 | 0 | 1 |
| Fatty acid-binding protein, intestinal | 0 | 1 | 1 | 2 |
| Prostaglandin G/H synthase 1 | 0 | 1 | 0 | 1 |
| Caspase-1 | 0 | 1 | 0 | 1 |
| Prostaglandin G/H synthase 2 | 0 | 1 | 0 | 1 |
| Caspase-3 | 0 | 1 | 0 | 1 |
| Caspase-4 | 0 | 1 | 0 | 1 |
| Caspase-5 | 0 | 1 | 0 | 1 |
| Caspase-9 | 0 | 1 | 0 | 1 |
| Cell division control protein 42 homolog | 0 | 1 | 0 | 1 |
| Ras-related C3 botulinum toxin substrate 1 | 0 | 1 | 0 | 1 |
| Serine/threonine-protein kinase PAK 1 | 0 | 1 | 0 | 1 |
| Ataxin-2 | 1 | 0 | 0 | 1 |
| peroxisome proliferator activated receptor gamma | 1 | 0 | 0 | 1 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 1 | 0 | 0 | 1 |
| Solute carrier family 22 member 3 | 0 | 0 | 0 | 1 |
| Spike glycoprotein | 2 | 0 | 0 | 2 |
| 5-hydroxytryptamine receptor 3E | 0 | 2 | 1 | 3 |
| D(1A) dopamine receptor | 1 | 0 | 0 | 1 |
| muscarinic acetylcholine receptor M1 | 1 | 0 | 0 | 1 |
| 5-hydroxytryptamine receptor 4 | 0 | 4 | 0 | 4 |
| 5-hydroxytryptamine receptor 3B | 0 | 2 | 1 | 3 |
| Albumin | 0 | 0 | 1 | 1 |
| Myeloperoxidase | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 2C | 0 | 3 | 0 | 3 |
| Alpha-2A adrenergic receptor | 0 | 4 | 1 | 5 |
| Cytochrome P450 2D6 | 0 | 4 | 0 | 5 |
| 5-hydroxytryptamine receptor 2A | 0 | 3 | 0 | 3 |
| Alpha-1B adrenergic receptor | 0 | 2 | 0 | 2 |
| D | 0 | 2 | 0 | 2 |
| D(3) dopamine receptor | 0 | 3 | 0 | 3 |
| 5-hydroxytryptamine receptor 1A | 0 | 2 | 0 | 2 |
| Alpha-2B adrenergic receptor | 0 | 2 | 0 | 2 |
| D(2) dopamine receptor | 0 | 1 | 0 | 1 |
| Alpha-2C adrenergic receptor | 0 | 2 | 0 | 2 |
| Acetylcholinesterase | 0 | 1 | 0 | 1 |
| Alpha-2A adrenergic receptor | 0 | 2 | 0 | 2 |
| Alpha-1D adrenergic receptor | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 3A | 0 | 1 | 0 | 1 |
| D(1B) dopamine receptor | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 2A | 0 | 4 | 0 | 4 |
| 5-hydroxytryptamine receptor 2C | 0 | 4 | 0 | 4 |
| 5-hydroxytryptamine receptor 1B | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 1D | 0 | 1 | 0 | 1 |
| D(4) dopamine receptor | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 1F | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 2B | 0 | 3 | 0 | 3 |
| 5-hydroxytryptamine receptor 3A | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 2B | 0 | 4 | 0 | 4 |
| Alpha-1A adrenergic receptor | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 3A | 0 | 2 | 1 | 3 |
| 5-hydroxytryptamine receptor 7 | 0 | 2 | 0 | 2 |
| 6-phosphogluconate dehydrogenase, decarboxylating | 0 | 1 | 0 | 1 |
| D(2) dopamine receptor | 0 | 4 | 0 | 4 |
| Lactoperoxidase | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 4 | 0 | 1 | 0 | 2 |
| 5-hydroxytryptamine receptor 3D | 0 | 2 | 1 | 3 |
| 5-hydroxytryptamine receptor 3C | 0 | 2 | 1 | 3 |
| 5-hydroxytryptamine receptor 3B | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 3B | 0 | 2 | 0 | 2 |
| Opioid receptor, delta 1b | 0 | 1 | 0 | 1 |
| Acetylcholinesterase | 0 | 2 | 0 | 2 |
| Opioid receptor homologue | 0 | 1 | 0 | 1 |
| ATP-dependent translocase ABCB1 | 0 | 1 | 0 | 1 |
| Acyl-CoA desaturase 1 | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M1 | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M3 | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M4 | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M5 | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M2 | 0 | 2 | 0 | 2 |
| Translocator protein | 0 | 0 | 1 | 1 |
| Histidine decarboxylase | 0 | 0 | 3 | 3 |
| ATP-dependent translocase ABCB1 | 0 | 1 | 0 | 1 |
| Proteinase-activated receptor 1 | 0 | 1 | 1 | 2 |
| Sodium-dependent serotonin transporter | 0 | 1 | 0 | 1 |
| Kappa-type opioid receptor | 0 | 5 | 3 | 10 |
| UDP-glucuronosyltransferase 1A3 | 0 | 0 | 0 | 1 |
| Nociceptin receptor | 0 | 1 | 0 | 1 |
| Mu-type opioid receptor | 0 | 1 | 0 | 1 |
| Beta-2 adrenergic receptor | 0 | 2 | 0 | 2 |
| Mas-related G-protein coupled receptor member X2 | 0 | 0 | 1 | 1 |
| Mu-type opioid receptor | 0 | 1 | 0 | 1 |
| RAR-related orphan receptor gamma | 2 | 0 | 0 | 2 |
| Cytochrome P450 2C9 | 0 | 1 | 0 | 1 |
| Adenosine receptor A1 | 0 | 1 | 0 | 1 |
| Cytochrome P450 2J2 | 0 | 1 | 0 | 1 |
| UDP-glucuronosyltransferase 1A8 | 0 | 0 | 0 | 2 |
| UDP-glucuronosyltransferase 1A1 | 0 | 0 | 0 | 1 |
| Nociceptin receptor | 0 | 1 | 0 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | 1 | 0 | 0 | 1 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | 1 | 0 | 0 | 1 |
| lysosomal alpha-glucosidase preproprotein | 1 | 0 | 0 | 1 |
| vitamin D3 receptor isoform VDRA | 1 | 0 | 0 | 1 |
| mitogen-activated protein kinase 1 | 1 | 0 | 0 | 1 |
| ubiquitin carboxyl-terminal hydrolase 2 isoform a | 1 | 0 | 0 | 1 |
| FAD-linked sulfhydryl oxidase ALR | 0 | 0 | 0 | 1 |
| geminin | 1 | 0 | 0 | 1 |
| Muscarinic acetylcholine receptor M2 | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M4 | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 1A | 0 | 1 | 1 | 2 |
| Muscarinic acetylcholine receptor M5 | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M1 | 0 | 1 | 1 | 2 |
| Glucose-6-phosphate 1-dehydrogenase | 0 | 1 | 0 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | 0 | 1 | 0 | 1 |
| Angiotensin-converting enzyme | 0 | 1 | 0 | 1 |
| Alpha-2B adrenergic receptor | 0 | 2 | 0 | 2 |
| Alpha-2C adrenergic receptor | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M3 | 0 | 2 | 0 | 2 |
| D(1A) dopamine receptor | 0 | 2 | 0 | 2 |
| UDP-glucuronosyltransferase 1A4 | 0 | 0 | 0 | 1 |
| Sodium-dependent noradrenaline transporter | 0 | 1 | 0 | 1 |
| Adenosine receptor A1 | 0 | 1 | 0 | 1 |
| Alpha-1D adrenergic receptor | 0 | 2 | 0 | 2 |
| Histamine H1 receptor | 0 | 1 | 0 | 1 |
| Sodium-dependent serotonin transporter | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 7 | 0 | 1 | 0 | 1 |
| Alpha-1A adrenergic receptor | 0 | 1 | 0 | 1 |
| Alpha-1B adrenergic receptor | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 6 | 0 | 2 | 0 | 2 |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 0 | 1 | 0 | 1 |
| Disintegrin and metalloproteinase domain-containing protein 17 | 1 | 0 | 0 | 1 |
| Inositol monophosphatase 1 | 1 | 0 | 0 | 1 |
| Transporter | 0 | 1 | 0 | 1 |
| Nuclear receptor subfamily 3 group C member 3 | 0 | 1 | 0 | 1 |
| Transporter | 0 | 1 | 0 | 1 |
| Sphingosine kinase 2 | 0 | 2 | 0 | 2 |
| Sphingosine kinase 1 | 0 | 1 | 0 | 1 |
| glp-1 receptor, partial | 1 | 0 | 0 | 1 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |