Growth failure from birth that is due to mutations in a gene (TRIM37) on chromosome 17q22-q23 which encodes a RING-B-box-coiled-coil protein.
| Synonym |
|---|
| Nanism, Mulibrey |
| Muscle-Liver-Brain-Eye Nanism |
| Mulibrey Nanism |
| Mulibrey Nanism Syndrome |
| Perheentupa Syndrome |
| Excerpt | Reference |
|---|---|
| "Mulibrey nanism is a rare autosomal recessive disorder with prenatal onset growth retardation (nanism) and dysmorphic features, including a wide range of abnormalities, such as cardiac disease (pericardial constriction, myocardial hypertrophy and fibrosis) and anomalies of muscle, liver, brain and eye, resulting in the acronym 'mulibrey'." | ( Hes, FJ; Morreau, H, 2009) |
| Timeframe | Studies, This Condition (%) | All Conditions % |
|---|---|---|
| pre-1990 | 0 (0.00) | 23.3326 |
| 1990's | 0 (0.00) | 12.5806 |
| 2000's | 2 (50.00) | 18.1394 |
| 2010's | 2 (50.00) | 28.8240 |
| 2020's | 0 (0.00) | 9.53 |
| Drug | Indicated | Relationship Strength | Studies | Trials |
|---|---|---|---|---|
| milrinone | 0 | low | 1 | 0 |
| atrial natriuretic factor | 0 | low | 1 | 0 |
| natriuretic peptide, brain | 0 | low | 1 | 0 |
| eye | 0 | low | 1 | 0 |