Page last updated: 2024-09-27

Mixed Tumor, Malignant

A malignant tumor composed of more than one type of neoplastic tissue. (Dorland, 27th ed)

Synonyms(1)

Synonym
Mixed Tumor, Malignant

Research

Studies (42)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's10 (23.81)12.5806
2000's18 (42.86)18.1394
2010's13 (30.95)28.8240
2020's1 (2.38)9.53
DrugIndicatedRelationship StrengthStudiesTrials
citric acid, anhydrous0low10
salicylic acid0low20
fluorouracil0low20
ifosfamide0low30
letrozole0low10
mitomycin0low20
17-alpha-hydroxyprogesterone0low10
eosine yellowish-(ys)0low10
deoxycytidine0low10
bromocriptine0medium11
paclitaxel0low20
etoposide0low10
propiconazole0low10
capecitabine0low20
triazoles0low10
fluorodeoxyglucose f180low20
zoledronic acid0low10
methotrexate0low10
carboplatin0low40
bromochloroacetic acid0low100
jaw0low10
gastrins0low10
glucagon0low20
sodium pertechnetate tc 99m0low10
epidermal growth factor0low10
cyclin d10low10
chondroitin sulfates0low10
metallothionein0low10

Protein Targets (454)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
acetylcholinesterase3003
pregnane X receptor4004
SMAD family member 23003
SMAD family member 33003
TDP1 protein9009
GLI family zinc finger 37007
Microtubule-associated protein tau3003
AR protein110011
progesterone receptor6006
glucocorticoid receptor [Homo sapiens]8008
retinoic acid nuclear receptor alpha variant 16006
retinoid X nuclear receptor alpha9009
estrogen-related nuclear receptor alpha7007
farnesoid X nuclear receptor6006
pregnane X nuclear receptor7007
estrogen nuclear receptor alpha120012
G4004
vitamin D (1,25- dihydroxyvitamin D3) receptor5005
arylsulfatase A2002
euchromatic histone-lysine N-methyltransferase 25005
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a6006
activating transcription factor 62002
nuclear receptor subfamily 1, group I, member 23003
chromobox protein homolog 17007
nuclear factor erythroid 2-related factor 2 isoform 18008
geminin7007
survival motor neuron protein isoform d4004
histone acetyltransferase KAT2A isoform 15005
lamin isoform A-delta106006
Voltage-dependent calcium channel gamma-2 subunit6006
Interferon beta4004
HLA class I histocompatibility antigen, B alpha chain 4004
Glucocorticoid receptor0202
Sex hormone-binding globulin0011
Glycine receptor subunit alpha-10202
Corticosteroid-binding globulin0101
Adenosine receptor A30202
Replicase polyprotein 1ab0101
Androgen receptor0404
Alpha-1B adrenergic receptor0202
Glutamate receptor 26006
Glycine receptor subunit beta0202
Glycine receptor subunit alpha-20202
Glycine receptor subunit alpha-30202
Mitogen-activated protein kinase 3 0101
Alpha-1A adrenergic receptor0202
Sodium-dependent dopamine transporter 0202
TAR DNA-binding protein 433003
Inositol hexakisphosphate kinase 14004
cytochrome P450 2C9, partial4004
ATP-dependent phosphofructokinase6006
RAR-related orphan receptor gamma7007
aldehyde dehydrogenase 1 family, member A15005
nuclear receptor subfamily 1, group I, member 37007
thyroid stimulating hormone receptor2002
Cellular tumor antigen p538008
Nuclear receptor ROR-gamma1001
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE5005
Genome polyprotein 0112
dopamine D1 receptor2002
thioredoxin reductase4004
ATAD5 protein, partial4004
Fumarate hydratase3003
GLS protein1001
regulator of G-protein signaling 41001
cytochrome P450 family 3 subfamily A polypeptide 44004
polyprotein3003
peroxisome proliferator activated receptor gamma8008
D(1A) dopamine receptor1001
vitamin D3 receptor isoform VDRA5005
thyroid hormone receptor beta isoform 28008
serine/threonine-protein kinase mTOR isoform 12002
peptidyl-prolyl cis-trans isomerase NIMA-interacting 12002
5-hydroxytryptamine receptor 40202
ATP-dependent translocase ABCB10202
ATP-dependent translocase ABCB10407
Beta-1 adrenergic receptor0202
Cytochrome P450 3A40303
5-hydroxytryptamine receptor 1A0101
Alpha-2A adrenergic receptor0202
D(2) dopamine receptor0213
Alpha-2B adrenergic receptor0202
Alpha-2C adrenergic receptor0202
D0101
D(3) dopamine receptor0101
5-hydroxytryptamine receptor 1A0202
Alpha-2B adrenergic receptor0101
ATP-dependent translocase ABCB10303
D(1A) dopamine receptor0202
Alpha-2C adrenergic receptor0101
Alpha-2A adrenergic receptor0101
Alpha-1D adrenergic receptor0202
D(1B) dopamine receptor0101
5-hydroxytryptamine receptor 2A0213
5-hydroxytryptamine receptor 2C0213
5-hydroxytryptamine receptor 1B0202
D(4) dopamine receptor0101
D(3) dopamine receptor0202
Alpha-synuclein0101
5-hydroxytryptamine receptor 2B0202
5-hydroxytryptamine receptor 60202
D(2) dopamine receptor0112
ATPase family AAA domain-containing protein 55005
Ataxin-25005
Liver carboxylesterase 10001
Chain A, TYROSYL-DNA PHOSPHODIESTERASE2002
Chain A, Putative fructose-1,6-bisphosphate aldolase1001
phosphopantetheinyl transferase4004
estrogen receptor 2 (ER beta)5005
cytochrome P450 2D62002
histone-lysine N-methyltransferase 2A isoform 2 precursor1001
DNA polymerase kappa isoform 12002
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain A, JmjC domain-containing histone demethylation protein 3A1001
hepatocyte nuclear factor 4-alpha isoform 20101
perilipin-50101
thyroid hormone receptor beta isoform a2002
perilipin-10101
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a0101
Beta-lactamase0101
Proto-oncogene tyrosine-protein kinase Src0202
3-dehydroquinate dehydratase0011
ATP-citrate synthase 0001
Ribonuclease T0001
Cell death-related nuclease 40001
3-dehydroquinate dehydratase0011
Prolyl 4-hydroxylase0101
Alpha-ketoglutarate-dependent dioxygenase FTO0101
Thymidine kinase 2 0101
Deoxycytidine kinase0001
Probable deoxycytidylate deaminase0001
Cytidine deaminase0001
AAA family ATPase 0001
Reverse transcriptase/RNaseH 0011
glp-1 receptor, partial3003
hypoxia-inducible factor 1 alpha subunit3003
caspase 7, apoptosis-related cysteine protease2002
67.9K protein5005
peroxisome proliferator-activated receptor delta6006
caspase-32002
LMP1 [Human herpesvirus 4]0001
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a1001
v-jun sarcoma virus 17 oncogene homolog (avian)2002
Histone H2A.x4004
nuclear factor erythroid 2-related factor 2 isoform 24004
heat shock protein beta-11001
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0202
DNA polymerase iota isoform a (long)4004
urokinase-type plasminogen activator precursor3003
plasminogen precursor3003
urokinase plasminogen activator surface receptor precursor3003
transactivating tegument protein VP16 [Human herpesvirus 1]0202
nuclear receptor coactivator 3 isoform a0202
ATP-binding cassette sub-family C member 30606
Multidrug resistance-associated protein 40607
Bile salt export pump0808
Prothrombin0001
Regulatory protein E20011
DNA topoisomerase 10102
DNA topoisomerase 2-alpha0117
Cytochrome P450 2C9 0101
Polyunsaturated fatty acid lipoxygenase ALOX150101
DNA topoisomerase 20001
UDP-glucuronosyltransferase 1A1 0102
Serum paraoxonase/arylesterase 10303
Glutamate receptor ionotropic, NMDA 1 0001
Caspase-30101
Glutamate receptor ionotropic, NMDA 2A 0001
Glutamate receptor ionotropic, NMDA 2B0001
Glutamate receptor ionotropic, NMDA 2C0001
DNA topoisomerase 2-alpha 0001
DNA topoisomerase 2-beta0118
Glutamate receptor ionotropic, NMDA 2D0001
Tubulin beta-2B chain0114
Integrase 0101
Similar to alpha-tubulin isoform 1 0114
Similar to alpha-tubulin isoform 1 0103
Glutamate receptor ionotropic, NMDA 3B0001
Canalicular multispecific organic anion transporter 10708
Solute carrier organic anion transporter family member 1B30405
Glutamate receptor ionotropic, NMDA 3A0001
Chain A, Uracil Phosphoribosyltransferase0101
Luciferase2002
interleukin 81001
endonuclease IV1001
Skn7p0001
Thrombopoietin1001
thyroid stimulating hormone receptor2002
EWS/FLI fusion protein6006
nonstructural protein 12002
IDH13003
peripheral myelin protein 22 isoform 11001
hemoglobin subunit beta1001
huntingtin isoform 21001
flap endonuclease 12002
Vpr1001
peripheral myelin protein 223003
muscleblind-like protein 1 isoform 12002
Solute carrier family 22 member 80001
Epidermal growth factor receptor0202
Amyloid-beta precursor protein1001
Thymidylate synthase0303
Aromatase0303
HSP40, subfamily A [Plasmodium falciparum 3D7]0001
Chain A, Beta-lactamase3003
GALC protein1001
Chymotrypsinogen A0101
USP1 protein, partial2002
cytochrome P450 2C19 precursor1001
runt-related transcription factor 1 isoform AML1b1001
core-binding factor subunit beta isoform 21001
cytochrome P450 3A4 isoform 11001
Gamma-aminobutyric acid receptor subunit pi1001
Carbonic anhydrase 20415
Estrogen receptor0101
Steryl-sulfatase0101
Gamma-aminobutyric acid receptor subunit beta-11001
Cytochrome P450 11B1, mitochondrial0101
Gamma-aminobutyric acid receptor subunit delta1001
Gamma-aminobutyric acid receptor subunit gamma-21001
Cytochrome P450 11B2, mitochondrial0101
Gamma-aminobutyric acid receptor subunit alpha-51001
Gamma-aminobutyric acid receptor subunit alpha-31001
Amine oxidase [flavin-containing] A 0101
Gamma-aminobutyric acid receptor subunit gamma-11001
Gamma-aminobutyric acid receptor subunit alpha-21001
Gamma-aminobutyric acid receptor subunit alpha-41001
Gamma-aminobutyric acid receptor subunit gamma-31001
Gamma-aminobutyric acid receptor subunit alpha-61001
Gamma-aminobutyric acid receptor subunit alpha-11001
Gamma-aminobutyric acid receptor subunit beta-31001
Gamma-aminobutyric acid receptor subunit beta-21001
GABA theta subunit1001
Gamma-aminobutyric acid receptor subunit epsilon1001
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain A, HADH2 protein1001
Chain B, HADH2 protein1001
Chain A, 2-oxoglutarate Oxygenase2002
Chain A, Ferritin light chain2002
acid sphingomyelinase1001
ClpP1001
15-lipoxygenase, partial1001
Thymidylate synthase 0101
alpha-galactosidase1001
Thymidylate synthase 0101
Bloom syndrome protein isoform 11001
cellular tumor antigen p53 isoform a1001
polyunsaturated fatty acid lipoxygenase ALOX121001
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 12002
transcriptional regulator ERG isoform 31001
importin subunit beta-1 isoform 11001
DNA polymerase beta1001
snurportin-11001
DNA polymerase eta isoform 11001
M-phase phosphoprotein 81001
caspase-1 isoform alpha precursor1001
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
Bile salt export pump0202
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0203
Dihydrofolate reductase0203
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Tyrosine-protein kinase ABL10112
Thymidylate synthase0202
Integrin beta-31102
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Integrin alpha-IIb1001
5-hydroxytryptamine receptor 2C0102
High mobility group protein B10022
Dihydrofolate reductase0101
Thymidylate synthase0101
Dihydrofolate reductase0224
Glucose-6-phosphate 1-dehydrogenase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0101
5-hydroxytryptamine receptor 2A0101
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Dihydrofolate reductase0202
Histidine decarboxylase0101
Trifunctional purine biosynthetic protein adenosine-30101
Cyclin-dependent kinase 20011
Bifunctional purine biosynthesis protein ATIC0202
Multidrug resistance-associated protein 1 0001
Delta-type opioid receptor0101
Mu-type opioid receptor0101
Kappa-type opioid receptor0101
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
6-phosphogluconate dehydrogenase, decarboxylating0101
Caspase-71001
Spike glycoprotein2002
Solute carrier organic anion transporter family member 1A30001
Dihydrofolate reductase0101
Pteridine reductase 10101
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Solute carrier family 22 member 60102
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Solute carrier family 22 member 200202
Dihydrofolate reductase 0101
Solute carrier family 22 member 80102
Solute carrier family 22 member 60202
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Multidrug resistance associated protein0102
Solute carrier family 22 member 110001
Protein-arginine deiminase type-40101
Broad substrate specificity ATP-binding cassette transporter ABCG20001
aryl hydrocarbon receptor2002
Indoleamine 2,3-dioxygenase 10101
Genome polyprotein 0101
NPC intracellular cholesterol transporter 1 precursor1001
Tubulin alpha-1A chain0012
Tubulin beta chain0011
Tubulin beta-4A chain0113
Receptor tyrosine-protein kinase erbB-20101
Tyrosine-protein kinase Fyn0101
Integrin alpha-V 0101
Tubulin beta chain0113
60 kDa chaperonin0101
Tubulin alpha-3C chain0113
Botulinum neurotoxin type A 0101
Apoptosis regulator Bcl-20101
60 kDa heat shock protein, mitochondrial0101
Fibroblast growth factor receptor 10101
UDP-glucuronosyltransferase 2B70101
UDP-glucuronosyltransferase 1-60101
Substance-K receptor0202
UDP-glucuronosyltransferase 1A40101
Cholecystokinin receptor type A0202
Melanocortin receptor 50202
UDP-glucuronosyltransferase 2B10 0101
Delta-type opioid receptor0202
10 kDa heat shock protein, mitochondrial0101
Tubulin alpha-1B chain0113
Tubulin alpha-4A chain0113
Tubulin beta-4B chain0113
Bcl-2-like protein 10101
Tyrosine-protein kinase Mer0101
Tubulin beta-3 chain0214
Tubulin beta-2A chain0113
Thiosulfate sulfurtransferase0101
Beta-tubulin 0101
Tubulin beta-8 chain0113
60 kDa chaperonin 0101
Tubulin alpha-3E chain0113
Tubulin alpha-1A chain0113
10 kDa chaperonin 0101
Tubulin alpha-1C chain0113
Tubulin beta-6 chain0113
Tubulin beta-2B chain0113
Tubulin beta-1 chain0113
Nucleotide-binding oligomerization domain-containing protein 20101
Solute carrier organic anion transporter family member 1B10202
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)1001
heat shock protein HSP 90-alpha isoform 20001
nuclear receptor ROR-gamma isoform 11001
Polyunsaturated fatty acid lipoxygenase ALOX15B1001
Histamine H2 receptor1001
Guanine nucleotide-binding protein G1001
heat shock protein 90, putative0001
chaperonin-containing TCP-1 beta subunit homolog1001
Estrogen receptor beta0001
Inhibitor of nuclear factor kappa-B kinase subunit beta0001
Solute carrier family 22 member 60101
Polyphenol oxidase 20102
Carbonic anhydrase 120202
5'-AMP-activated protein kinase subunit beta-20001
Carbonic anhydrase 10303
Albumin0101
Polymerase acidic protein0011
Carbonic anhydrase 30101
Stromelysin-10011
Tyrosine-protein phosphatase YopH0101
Aldo-keto reductase family 1 member B10101
Prolyl 4-hydroxylase subunit alpha-10101
Tyrosine-protein phosphatase non-receptor type 10103
Estrogen receptor0001
Acetylcholinesterase0101
Carbonic anhydrase 40101
Prostaglandin G/H synthase 10101
Carbonic anhydrase 60101
Cystathionine gamma-lyase0101
Carbonic anhydrase 5A, mitochondrial0101
Prostaglandin G/H synthase 20101
Carbonic anhydrase 70101
5'-AMP-activated protein kinase subunit gamma-10001
5'-AMP-activated protein kinase catalytic subunit alpha-20001
Xanthine dehydrogenase/oxidase0101
5'-AMP-activated protein kinase catalytic subunit alpha-10001
Carbonic anhydrase 90202
Carbonic anhydrase0101
Solute carrier family 22 member 70001
Nicotinate phosphoribosyltransferase0101
Ubiquitin-like domain-containing CTD phosphatase 10101
Carbonic anhydrase 150101
Carbonic anhydrase 130101
5'-AMP-activated protein kinase subunit gamma-30001
5'-AMP-activated protein kinase subunit gamma-20001
Carbonic anhydrase 140202
Carbonic anhydrase 5B, mitochondrial0101
5'-AMP-activated protein kinase subunit beta-10001
Butyrophilin subfamily 3 member A10012
Geranylgeranyl pyrophosphate synthase0203
72 kDa type IV collagenase0101
Farnesyl pyrophosphate synthase0202
Matrix metalloproteinase-90101
Neutrophil collagenase0101
Farnesyl diphosphate synthase0101
Matrix metalloproteinase-140101
Farnesyl pyrophosphate synthase 0202
Geranylgeranyl pyrophosphate synthase0202
Farnesyl pyrophosphate synthase 0101
H0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]