| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| TDP1 protein | 6 | 0 | 0 | 6 |
| serine/threonine-protein kinase PLK1 | 1 | 0 | 0 | 1 |
| DNA polymerase iota isoform a (long) | 5 | 0 | 0 | 5 |
| geminin | 5 | 0 | 0 | 5 |
| Rap guanine nucleotide exchange factor 3 | 4 | 0 | 0 | 4 |
| NPC1-like intracellular cholesterol transporter 1 | 0 | 0 | 1 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 2 | 0 | 0 | 2 |
| Chain A, Membrane lipoprotein tmpC | 0 | 0 | 1 | 1 |
| Chain A, Membrane lipoprotein tmpC | 0 | 0 | 1 | 1 |
| Chain A, Membrane lipoprotein tmpC | 0 | 0 | 1 | 1 |
| Chain A, Structure of PAE2307 in complex with adenosine | 0 | 0 | 1 | 1 |
| Chain B, Structure of PAE2307 in complex with adenosine | 0 | 0 | 1 | 1 |
| Chain A, ADENOSINE RECEPTOR A2A | 0 | 1 | 0 | 1 |
| Chain A, ADENOSINE RECEPTOR A2A | 0 | 1 | 0 | 1 |
| Chain A, tRNA (guanine-N(1)-)-methyltransferase | 0 | 0 | 1 | 1 |
| Chain A, Uncharacterized protein MJ0883 | 0 | 0 | 1 | 1 |
| AR protein | 5 | 0 | 0 | 5 |
| signal transducer and activator of transcription 6, interleukin-4 induced | 1 | 0 | 0 | 1 |
| regulator of G-protein signaling 4 | 1 | 0 | 0 | 1 |
| glucocorticoid receptor [Homo sapiens] | 7 | 0 | 0 | 7 |
| retinoid X nuclear receptor alpha | 3 | 0 | 0 | 3 |
| estrogen nuclear receptor alpha | 8 | 0 | 0 | 8 |
| NPYLR7B | 0 | 0 | 1 | 1 |
| arylsulfatase A | 1 | 0 | 0 | 1 |
| IDH1 | 3 | 0 | 0 | 3 |
| Histone H2A.x | 1 | 0 | 0 | 1 |
| glycogen synthase kinase-3 beta isoform 1 | 0 | 0 | 1 | 1 |
| mitogen-activated protein kinase 1 | 1 | 0 | 0 | 1 |
| flap endonuclease 1 | 1 | 0 | 0 | 1 |
| nuclear receptor ROR-gamma isoform 1 | 2 | 0 | 0 | 2 |
| peripheral myelin protein 22 | 3 | 0 | 0 | 3 |
| survival motor neuron protein isoform d | 2 | 0 | 0 | 2 |
| high affinity choline transporter 1 isoform a | 0 | 1 | 0 | 1 |
| Sodium/nucleoside cotransporter 1 | 0 | 2 | 0 | 2 |
| Calcium dependent protein kinase | 0 | 1 | 0 | 1 |
| Mitogen-activated protein kinase kinase kinase 7 | 0 | 0 | 1 | 1 |
| Sodium/nucleoside cotransporter 2 | 0 | 2 | 0 | 2 |
| Voltage-dependent calcium channel gamma-2 subunit | 5 | 0 | 0 | 5 |
| Purine nucleoside phosphorylase | 0 | 1 | 0 | 1 |
| Epidermal growth factor receptor | 0 | 1 | 0 | 1 |
| Phosphoglycerate kinase 1 | 0 | 1 | 0 | 1 |
| Adenosine deaminase | 0 | 0 | 0 | 1 |
| Avidin | 0 | 0 | 1 | 1 |
| Adenosine deaminase | 0 | 0 | 0 | 1 |
| Glyceraldehyde-3-phosphate dehydrogenase | 0 | 2 | 0 | 2 |
| Receptor tyrosine-protein kinase erbB-2 | 0 | 1 | 0 | 1 |
| Insulin receptor | 0 | 0 | 0 | 1 |
| Phosphoglycerate kinase 2 | 0 | 1 | 0 | 1 |
| Heat shock protein HSP 90-alpha | 0 | 1 | 1 | 2 |
| Platelet-derived growth factor receptor beta | 0 | 0 | 0 | 1 |
| Adenosine receptor A3 | 0 | 2 | 2 | 5 |
| Heat shock 70 kDa protein 1A | 0 | 1 | 0 | 1 |
| Heat shock cognate 71 kDa protein | 0 | 0 | 1 | 1 |
| Fibroblast growth factor receptor 1 | 0 | 0 | 0 | 1 |
| Inosine-5'-monophosphate dehydrogenase 2 | 0 | 1 | 0 | 1 |
| Endoplasmin | 0 | 1 | 1 | 2 |
| Glutamate receptor 2 | 5 | 0 | 0 | 5 |
| Inosine-5'-monophosphate dehydrogenase 1 | 0 | 1 | 0 | 1 |
| Fibroblast growth factor receptor 2 | 0 | 0 | 0 | 1 |
| Fibroblast growth factor receptor 4 | 0 | 0 | 0 | 1 |
| Fibroblast growth factor receptor 3 | 0 | 0 | 0 | 1 |
| Streptavidin | 0 | 0 | 1 | 1 |
| Adenosylhomocysteinase | 0 | 0 | 0 | 1 |
| Adenosine receptor A1 | 0 | 1 | 1 | 2 |
| Adenosine receptor A3 | 0 | 1 | 0 | 1 |
| Adenosine receptor A2a | 0 | 1 | 3 | 5 |
| Adenosine receptor A2b | 0 | 0 | 1 | 2 |
| Adenosine receptor A2b | 0 | 1 | 1 | 2 |
| Adenylate kinase 2, mitochondrial | 0 | 1 | 0 | 1 |
| Adenosine receptor A1 | 0 | 2 | 2 | 5 |
| Adenosine receptor A2a | 0 | 1 | 1 | 2 |
| Adenylate kinase isoenzyme 1 | 0 | 1 | 0 | 1 |
| Phosphatidylinositol 4-kinase alpha | 0 | 2 | 0 | 3 |
| Adenosine receptor A1 | 0 | 0 | 1 | 1 |
| Adenosine kinase | 0 | 0 | 0 | 1 |
| Adenosine deaminase | 0 | 0 | 0 | 1 |
| Equilibrative nucleoside transporter 2 | 0 | 2 | 0 | 2 |
| Phosphatidylinositol 4-kinase type 2-beta | 0 | 2 | 0 | 3 |
| Histone-lysine N-methyltransferase, H3 lysine-79 specific | 0 | 1 | 0 | 1 |
| Equilibrative nucleoside transporter 1 | 0 | 2 | 0 | 2 |
| Phosphatidylinositol 4-kinase type 2-alpha | 0 | 2 | 0 | 3 |
| Solute carrier family 28 member 3 | 0 | 2 | 0 | 2 |
| Adenosine kinase | 0 | 1 | 0 | 2 |
| Phosphatidylinositol 4-kinase beta | 0 | 2 | 0 | 3 |
| 5-methylthioadenosine/S-adenosylhomocysteine deaminase | 0 | 0 | 0 | 1 |
| Adenosine transporter 1 | 0 | 0 | 0 | 1 |
| interleukin 8 | 1 | 0 | 0 | 1 |
| thyroid stimulating hormone receptor | 1 | 0 | 0 | 1 |
| estrogen receptor 2 (ER beta) | 3 | 0 | 0 | 3 |
| progesterone receptor | 4 | 0 | 0 | 4 |
| estrogen-related nuclear receptor alpha | 6 | 0 | 0 | 6 |
| euchromatic histone-lysine N-methyltransferase 2 | 3 | 0 | 0 | 3 |
| Bloom syndrome protein isoform 1 | 2 | 0 | 0 | 2 |
| transcriptional regulator ERG isoform 3 | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform 2 | 4 | 0 | 0 | 4 |
| ras-related protein Rab-9A | 1 | 0 | 0 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 2 | 0 | 0 | 2 |
| lamin isoform A-delta10 | 2 | 0 | 0 | 2 |
| ATP-binding cassette sub-family C member 3 | 0 | 2 | 0 | 2 |
| Multidrug resistance-associated protein 4 | 0 | 2 | 0 | 2 |
| Polyphenol oxidase 2 | 0 | 1 | 0 | 1 |
| Bile salt export pump | 0 | 5 | 0 | 5 |
| Hypoxanthine-guanine phosphoribosyltransferase | 0 | 0 | 0 | 1 |
| Cellular tumor antigen p53 | 5 | 0 | 0 | 5 |
| Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase | 0 | 1 | 0 | 1 |
| Xanthine dehydrogenase/oxidase | 0 | 2 | 0 | 2 |
| Nuclear receptor ROR-gamma | 0 | 1 | 0 | 1 |
| Xanthine dehydrogenase/oxidase | 0 | 2 | 1 | 4 |
| Purine nucleoside phosphorylase | 0 | 0 | 1 | 1 |
| TAR DNA-binding protein 43 | 2 | 0 | 0 | 2 |
| Canalicular multispecific organic anion transporter 1 | 0 | 2 | 0 | 2 |
| Shiga toxin subunit A | 0 | 1 | 0 | 1 |
| Histamine H3 receptor | 0 | 1 | 0 | 1 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | 2 | 0 | 0 | 2 |
| Chain A, 2-oxoglutarate Oxygenase | 2 | 0 | 0 | 2 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | 1 | 0 | 0 | 1 |
| Chain A, Xcogt | 0 | 0 | 1 | 1 |
| Chain A, Xcogt | 0 | 0 | 1 | 1 |
| Chain A, Xcogt | 0 | 0 | 1 | 1 |
| phosphopantetheinyl transferase | 2 | 0 | 0 | 2 |
| USP1 protein, partial | 2 | 0 | 0 | 2 |
| Microtubule-associated protein tau | 1 | 0 | 0 | 1 |
| vitamin D3 receptor isoform VDRA | 3 | 0 | 0 | 3 |
| ubiquitin carboxyl-terminal hydrolase 2 isoform a | 1 | 0 | 0 | 1 |
| Disintegrin and metalloproteinase domain-containing protein 17 | 1 | 0 | 0 | 1 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | 1 | 0 | 0 | 1 |
| acid sphingomyelinase | 1 | 0 | 0 | 1 |
| GLI family zinc finger 3 | 5 | 0 | 0 | 5 |
| apical membrane antigen 1, AMA1 | 1 | 0 | 0 | 1 |
| retinoic acid nuclear receptor alpha variant 1 | 7 | 0 | 0 | 7 |
| farnesoid X nuclear receptor | 3 | 0 | 0 | 3 |
| Type IV secretion-like conjugative transfer relaxase protein TraI | 0 | 1 | 0 | 1 |
| aryl hydrocarbon receptor | 5 | 0 | 0 | 5 |
| histone acetyltransferase KAT2A isoform 1 | 3 | 0 | 0 | 3 |
| Carbonic anhydrase 1 | 0 | 2 | 0 | 2 |
| Carbonic anhydrase 2 | 0 | 2 | 0 | 2 |
| Carbonic anhydrase 4 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase | 0 | 2 | 0 | 2 |
| Carbonic anhydrase 15 | 0 | 1 | 0 | 1 |
| acetylcholinesterase | 1 | 0 | 0 | 1 |
| RAR-related orphan receptor gamma | 5 | 0 | 0 | 5 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 3 | 0 | 0 | 3 |
| cytochrome P450 2D6 | 1 | 0 | 0 | 1 |
| thyroid stimulating hormone receptor | 1 | 0 | 0 | 1 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | 2 | 0 | 0 | 2 |
| cellular tumor antigen p53 isoform a | 1 | 0 | 0 | 1 |
| Integrin beta-3 | 1 | 0 | 0 | 1 |
| Integrin alpha-IIb | 1 | 0 | 0 | 1 |
| Chain A, NAD-dependent deacetylase | 0 | 1 | 0 | 1 |
| activating transcription factor 6 | 1 | 0 | 0 | 1 |
| Caspase-7 | 1 | 0 | 0 | 1 |
| caspase-3 | 1 | 0 | 0 | 1 |
| Poly [ADP-ribose] polymerase 2 | 0 | 1 | 0 | 1 |
| NAD-dependent histone deacetylase SIR2 | 0 | 1 | 0 | 1 |
| Coagulation factor VII | 0 | 1 | 0 | 1 |
| Poly [ADP-ribose] polymerase 1 | 0 | 1 | 0 | 1 |
| Tissue factor | 0 | 1 | 0 | 1 |
| Cytochrome P450 3A5 | 0 | 1 | 0 | 1 |
| NAD-dependent protein deacetylase HST2 | 0 | 1 | 0 | 1 |
| Fatty-acid amide hydrolase 1 | 0 | 1 | 0 | 1 |
| Protein mono-ADP-ribosyltransferase PARP15 | 0 | 1 | 0 | 1 |
| NAD(+) hydrolase SARM1 | 0 | 1 | 0 | 1 |
| NAD-dependent protein deacetylase sirtuin-2 | 0 | 1 | 0 | 1 |
| NAD-dependent protein deacetylase sirtuin-6 | 0 | 1 | 0 | 1 |
| NAD-dependent protein deacetylase sirtuin-1 | 0 | 1 | 0 | 1 |
| ATPase family AAA domain-containing protein 5 | 3 | 0 | 0 | 3 |
| Ataxin-2 | 3 | 0 | 0 | 3 |
| NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 0 | 1 | 0 | 1 |
| NAD-dependent protein deacylase sirtuin-5, mitochondrial | 0 | 1 | 0 | 1 |
| NAD-dependent protein deacetylase | 0 | 1 | 0 | 1 |
| Gag-Pol polyprotein | 0 | 1 | 0 | 1 |
| Cytochrome P450 2D6 | 0 | 1 | 0 | 1 |
| Gag-Pol polyprotein | 0 | 1 | 0 | 1 |
| Spike glycoprotein | 1 | 0 | 0 | 1 |
| Protease | 0 | 3 | 0 | 3 |
| luciferase | 0 | 0 | 0 | 1 |
| hypoxia-inducible factor 1 alpha subunit | 1 | 0 | 0 | 1 |
| pregnane X nuclear receptor | 3 | 0 | 0 | 3 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 2 | 0 | 0 | 2 |
| nuclear receptor subfamily 1, group I, member 2 | 1 | 0 | 0 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | 1 | 0 | 0 | 1 |
| Interferon beta | 3 | 0 | 0 | 3 |
| Fatty acid-binding protein, liver | 0 | 1 | 0 | 1 |
| Estrogen receptor | 0 | 2 | 0 | 2 |
| Glucocorticoid receptor | 0 | 2 | 1 | 8 |
| Progesterone receptor | 0 | 2 | 0 | 3 |
| Glucocorticoid receptor | 0 | 1 | 1 | 2 |
| Glucocorticoid receptor | 0 | 0 | 1 | 1 |
| Glycine receptor subunit alpha-1 | 0 | 2 | 0 | 2 |
| Corticosteroid-binding globulin | 0 | 1 | 0 | 1 |
| Mineralocorticoid receptor | 0 | 2 | 1 | 3 |
| Androgen receptor | 0 | 2 | 0 | 2 |
| Cytochrome P450 2C9 | 0 | 2 | 0 | 2 |
| Glutamine synthetase | 0 | 0 | 1 | 1 |
| Androgen receptor | 0 | 1 | 0 | 1 |
| Glycine receptor subunit beta | 0 | 2 | 0 | 2 |
| Glycine receptor subunit alpha-2 | 0 | 2 | 0 | 2 |
| Glycine receptor subunit alpha-3 | 0 | 2 | 0 | 2 |
| Histamine H1 receptor | 0 | 0 | 1 | 1 |
| Prostaglandin G/H synthase 2 | 0 | 1 | 0 | 1 |
| Nociceptin receptor | 0 | 0 | 1 | 1 |
| Cytochrome P450 2J2 | 0 | 1 | 0 | 1 |
| Estrogen receptor beta | 0 | 2 | 0 | 2 |
| Chain A, Beta-lactamase | 3 | 0 | 0 | 3 |
| Chain A, Ferritin light chain | 2 | 0 | 0 | 2 |
| glp-1 receptor, partial | 1 | 0 | 0 | 1 |
| pregnane X receptor | 1 | 0 | 0 | 1 |
| SMAD family member 2 | 1 | 0 | 0 | 1 |
| SMAD family member 3 | 1 | 0 | 0 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | 1 | 0 | 0 | 1 |
| nonstructural protein 1 | 1 | 0 | 0 | 1 |
| peroxisome proliferator-activated receptor delta | 1 | 0 | 0 | 1 |
| peroxisome proliferator activated receptor gamma | 2 | 0 | 0 | 2 |
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 1 | 0 | 0 | 1 |
| chromobox protein homolog 1 | 2 | 0 | 0 | 2 |
| thyroid hormone receptor beta isoform a | 2 | 0 | 0 | 2 |
| heat shock protein HSP 90-alpha isoform 2 | 0 | 0 | 0 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | 1 | 0 | 0 | 1 |
| Cytochrome P450 3A4 | 0 | 1 | 0 | 1 |
| Histamine H2 receptor | 1 | 0 | 0 | 1 |
| Guanine nucleotide-binding protein G | 1 | 0 | 0 | 1 |
| heat shock protein 90, putative | 0 | 0 | 0 | 1 |
| Butyrophilin subfamily 3 member A1 | 0 | 0 | 1 | 1 |
| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase | 0 | 1 | 0 | 1 |
| Geranylgeranyl pyrophosphate synthase | 0 | 2 | 0 | 2 |
| Farnesyl pyrophosphate synthase | 0 | 2 | 0 | 2 |
| Farnesyl pyrophosphate synthase | 0 | 2 | 0 | 2 |
| Farnesyl diphosphate synthase | 0 | 1 | 0 | 1 |
| Farnesyl pyrophosphate synthase | 0 | 1 | 0 | 1 |
| H | 0 | 1 | 0 | 1 |
| Phosphotransferase | 0 | 1 | 0 | 1 |
| Farnesyl diphosphate synthase | 0 | 1 | 0 | 1 |
| Carbonic anhydrase | 0 | 1 | 0 | 1 |
| Eyes absent homolog 2 | 0 | 1 | 0 | 1 |
| Mu-type opioid receptor | 0 | 1 | 0 | 1 |
| Carbonic anhydrase | 0 | 1 | 0 | 1 |
| G | 1 | 0 | 0 | 1 |
| DNA polymerase eta isoform 1 | 1 | 0 | 0 | 1 |
| HLA class I histocompatibility antigen, B alpha chain | 1 | 0 | 0 | 1 |
| Alpha-synuclein | 0 | 1 | 0 | 1 |
| Inositol hexakisphosphate kinase 1 | 1 | 0 | 0 | 1 |
| cytochrome P450 2C9, partial | 1 | 0 | 0 | 1 |
| thioredoxin reductase | 1 | 0 | 0 | 1 |
| thioredoxin glutathione reductase | 1 | 0 | 0 | 1 |
| Chain A, HADH2 protein | 1 | 0 | 0 | 1 |
| Chain B, HADH2 protein | 1 | 0 | 0 | 1 |
| PPM1D protein | 1 | 0 | 0 | 1 |
| aldehyde dehydrogenase 1 family, member A1 | 1 | 0 | 0 | 1 |
| EWS/FLI fusion protein | 1 | 0 | 0 | 1 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | 1 | 0 | 0 | 1 |
| Albumin | 0 | 0 | 1 | 1 |
| Albumin | 0 | 0 | 1 | 1 |
| Proprotein convertase subtilisin/kexin type 7 | 0 | 1 | 0 | 1 |
| Vitamin K epoxide reductase complex subunit 1-like protein 1 | 0 | 1 | 0 | 1 |
| Vitamin K epoxide reductase complex subunit 1 | 0 | 1 | 0 | 1 |
| Vitamin K epoxide reductase complex subunit 1-like protein 1 | 0 | 1 | 0 | 1 |
| Vitamin K epoxide reductase complex subunit 1 | 0 | 2 | 0 | 2 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |