Page last updated: 2024-09-27

Meconium Ileus

Intestinal obstruction caused by congealed MECONIUM in the distal ILEUM and CECUM. It presents shortly after birth as a failure to pass meconium and frequently occurs in infants with CYSTIC FIBROSIS.

Synonyms(1)

Synonym
Meconium Ileus

Research

Studies (12)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's0 (0.00)12.5806
2000's0 (0.00)18.1394
2010's2 (16.67)28.8240
2020's10 (83.33)9.53
DrugIndicatedRelationship StrengthStudiesTrials
chlorine0low10
iodine0low20
diatrizoate meglumine0low30
morphine0medium90
trypsinogen0low40

Protein Targets (70)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Carbonic anhydrase 10101
Carbonic anhydrase 20101
Carbonic anhydrase 40101
Carbonic anhydrase0101
Carbonic anhydrase 150101
thioredoxin reductase1001
Hsf1 protein0011
euchromatic histone-lysine N-methyltransferase 21001
chromobox protein homolog 11001
geminin1001
survival motor neuron protein isoform d1001
Luciferase1001
acetylcholinesterase1001
hypoxia-inducible factor 1 alpha subunit1001
RAR-related orphan receptor gamma1001
progesterone receptor1001
retinoic acid nuclear receptor alpha variant 11001
retinoid X nuclear receptor alpha1001
estrogen-related nuclear receptor alpha1001
pregnane X nuclear receptor1001
estrogen nuclear receptor alpha1001
peroxisome proliferator activated receptor gamma1001
aryl hydrocarbon receptor1001
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a1001
activating transcription factor 61001
v-jun sarcoma virus 17 oncogene homolog (avian)1001
histone deacetylase 9 isoform 31001
nuclear factor erythroid 2-related factor 2 isoform 11001
Voltage-dependent calcium channel gamma-2 subunit1001
Glutamate receptor 21001
Opioid receptor, delta 1b 0101
Solute carrier family 22 member 1 0101
Acetylcholinesterase0101
Opioid receptor homologue0101
Bile salt export pump0101
ATP-dependent translocase ABCB10101
Acyl-CoA desaturase 10101
ATP-dependent translocase ABCB10101
Muscarinic acetylcholine receptor M10101
Muscarinic acetylcholine receptor M30101
Muscarinic acetylcholine receptor M40101
Cytochrome P450 3A40112
Muscarinic acetylcholine receptor M50101
Alpha-2A adrenergic receptor0011
Muscarinic acetylcholine receptor M20101
Translocator protein0011
Histidine decarboxylase0011
ATP-dependent translocase ABCB10101
Proteinase-activated receptor 10112
Sodium-dependent serotonin transporter0101
Delta-type opioid receptor0102
Delta-type opioid receptor0214
Kappa-type opioid receptor0214
Mu-type opioid receptor0216
Kappa-type opioid receptor0214
Mu-type opioid receptor0214
UDP-glucuronosyltransferase 1A30001
Delta-type opioid receptor0214
Kappa-type opioid receptor0202
Kappa-type opioid receptor0214
Mu-type opioid receptor0215
Nociceptin receptor0101
5-hydroxytryptamine receptor 70101
Mu-type opioid receptor0101
Mu-type opioid receptor0202
Potassium voltage-gated channel subfamily H member 20101
Beta-2 adrenergic receptor0101
Mas-related G-protein coupled receptor member X20011
Mu-type opioid receptor0101
Sigma non-opioid intracellular receptor 10101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]