Mammary Paget Disease

An intraductal in situ carcinoma of the breast, characterized clinically by eczema-like inflammatory skin changes and histologically by infiltration of the dermis by malignant cells (Paget's cells).

Synonym
Paget's Disease of the Nipple and Areola
Mammary Paget Disease
Pigmented Mammary Paget Disease
Paget Disease of Breast
Mammary Paget's Disease
Paget Disease, Mammary
Paget's Disease of Breast
Paget's Disease of the Breast
Paget's Disease of the Nipple
Paget's Disease, Mammary

Excerpt	Reference
"Paget's disease of the breast is a rare condition with an incidence of 3% to 5% of all mammary malignancies."	( Bodnar, M; Miller, OF; Tyler, W, 1999)
"The histogenesis of mammary Paget's disease is controversial."	( Mai, KT, 1999)

Excerpt	Reference
"Mammary Paget's disease has been said to result from epidermal spread by contiguity of primary intraductal carcinoma."	( Cohen, C; DeRose, PB; Guarner, J, 1993)

Excerpt	Reference
"Thirty-five women with biopsy-proven Paget's disease of the nipple were treated over a 10 year period at the Breast Cancer Unit, Guy's Hospital."	( Chaudary, MA; Lane, EB; Miller, NA; Millis, RR, 1986)
"An epithelioid hemangioendothelioma and Paget's disease of the breast were treated with topical imiquimod 5% cream with very impressive results."	( Martínez, MI; Mihm, MC; Sanchez-Carpintero, I, 2006)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	20 (33.90)	23.3326
1990's	16 (27.12)	12.5806
2000's	14 (23.73)	18.1394
2010's	8 (13.56)	28.8240
2020's	1 (1.69)	9.53

Drug	Relationship Strength	Studies
5-aminovaleric acid	low	1
aminoglutethimide	low	1
erythrosine	low	1
iohexol	low	1
fluorescein-5-isothiocyanate	low	1
technetium	low	1
paclitaxel	low	2
imiquimod	low	4
thomsen-friedenreich antigen	low	1
metaperiodate	low	1
fluorodeoxyglucose f18	low	2
levobupivacaine	low	1
glycogen	low	2
cefoxitin	low	1
diethylstilbestrol	low	1
bromochloroacetic acid	low	26
dienestrol	low	1
calcitriol	low	1
radium	low	1
involucrin	low	2
mart-1 antigen	low	1
technetium tc 99m sestamibi	low	2
calcipotriene	low	1
cyclin d1	low	3
caseins	low	1

Protein Targets (397)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Gamma-aminobutyric acid receptor subunit rho-3	0	0	0	1
thioredoxin reductase	3	0	0	3
NFKB1 protein, partial	1	0	0	1
arylsulfatase A	3	0	0	3
cytochrome P450 2D6 isoform 1	3	0	0	3
Gamma-aminobutyric acid receptor subunit rho-1	0	0	0	1
Gamma-aminobutyric acid receptor subunit rho-2	0	0	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Glutamate receptor 1	0	1	0	1
Glutamate receptor 2	0	1	0	1
Glutamate receptor 3	0	1	0	1
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Solute carrier family 15 member 1	0	1	0	1
Glutamate receptor 4	0	1	0	1
ATP-dependent phosphofructokinase	3	0	0	3
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	4	0	0	4
cytochrome P450 family 3 subfamily A polypeptide 4	6	0	0	6
estrogen-related nuclear receptor alpha	7	0	0	7
pregnane X nuclear receptor	6	0	0	6
estrogen nuclear receptor alpha	9	0	0	9
IDH1	4	0	0	4
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	4	0	0	4
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	4	0	0	4
peripheral myelin protein 22 isoform 1	1	0	0	1
potassium voltage-gated channel subfamily H member 2 isoform d	3	0	0	3
transcriptional regulator ERG isoform 3	2	0	0	2
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	1	0	0	1
geminin	8	0	0	8
cytochrome P450 3A4 isoform 1	6	0	0	6
Gamma-aminobutyric acid receptor subunit pi	6	0	0	6
ATP-binding cassette sub-family C member 3	0	7	0	7
Multidrug resistance-associated protein 4	0	7	0	7
Sterol O-acyltransferase 1	0	1	0	1
Bile salt export pump	0	7	0	7
Cholesterol side-chain cleavage enzyme, mitochondrial	0	1	0	1
Triosephosphate isomerase	0	1	0	1
Steroid 17-alpha-hydroxylase/17,20 lyase	0	1	0	1
Cholesterol side-chain cleavage enzyme, mitochondrial	0	1	0	1
Aromatase	0	2	0	6
Gamma-aminobutyric acid receptor subunit beta-1	6	0	0	6
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	6	0	0	6
Gamma-aminobutyric acid receptor subunit gamma-2	6	0	0	6
Gamma-aminobutyric acid receptor subunit alpha-5	6	0	0	6
Gamma-aminobutyric acid receptor subunit alpha-3	6	0	0	6
Aromatase	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-1	6	0	0	6
Gamma-aminobutyric acid receptor subunit alpha-2	6	0	0	6
Thromboxane-A synthase	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-4	6	0	0	6
Gamma-aminobutyric acid receptor subunit gamma-3	6	0	0	6
Cytochrome P450 11B2, mitochondrial	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	6	0	0	6
Delta-type opioid receptor	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	6	0	0	6
Gamma-aminobutyric acid receptor subunit beta-3	6	0	0	6
Gamma-aminobutyric acid receptor subunit beta-2	6	0	0	6
GABA theta subunit	6	0	0	6
Canalicular multispecific organic anion transporter 1	0	7	0	7
Gamma-aminobutyric acid receptor subunit epsilon	6	0	0	6
RAR-related orphan receptor gamma	4	0	0	4
AR protein	9	0	0	9
aldehyde dehydrogenase 1 family, member A1	3	0	0	3
nuclear receptor subfamily 1, group I, member 3	6	0	0	6
retinoic acid nuclear receptor alpha variant 1	6	0	0	6
thyroid stimulating hormone receptor	4	0	0	4
nuclear factor erythroid 2-related factor 2 isoform 1	6	0	0	6
Cellular tumor antigen p53	8	0	0	8
Nuclear receptor ROR-gamma	2	0	0	2
Chain A, Vitamin D Nuclear Receptor	0	0	1	1
Chain A, Beta-lactamase	5	0	0	5
Chain A, Ferritin light chain	4	0	0	4
Vitamin D3 receptor	0	0	1	1
USP1 protein, partial	4	0	0	4
PPM1D protein	3	0	0	3
Microtubule-associated protein tau	4	0	0	4
thioredoxin glutathione reductase	2	0	0	2
euchromatic histone-lysine N-methyltransferase 2	4	0	0	4
mitogen-activated protein kinase 1	3	0	0	3
nuclear receptor ROR-gamma isoform 1	3	0	0	3
peripheral myelin protein 22	4	0	0	4
Interferon beta	6	0	0	6
Vitamin D-binding protein	0	0	1	1
Cytochrome P450 1A2	0	0	0	1
Cytochrome P450 3A4	0	3	0	4
Androgen receptor	0	1	0	1
Cytochrome P450 2D6	0	2	0	2
Vitamin D3 receptor	0	1	2	4
Cytochrome P450 2C9	0	1	0	2
Vitamin D3 receptor	0	1	1	3
Retinoic acid receptor RXR-alpha	0	0	1	1
Cytochrome P450 2C19	0	1	0	1
Kappa-type opioid receptor	0	0	1	1
Vitamin D3 receptor	0	0	1	1
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	0	0	1	1
Vitamin D3 receptor	0	1	1	2
Transporter	0	1	0	1
Vitamin D3 receptor A	0	0	2	2
Luciferase	4	0	0	4
glp-1 receptor, partial	2	0	0	2
15-lipoxygenase, partial	2	0	0	2
hypoxia-inducible factor 1 alpha subunit	4	0	0	4
GLS protein	3	0	0	3
TDP1 protein	6	0	0	6
GLI family zinc finger 3	5	0	0	5
Estrogen receptor 1	0	0	1	1
Smad3	2	0	0	2
caspase 7, apoptosis-related cysteine protease	2	0	0	2
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	2	0	0	2
estrogen receptor 2 (ER beta)	4	0	0	4
retinoid X nuclear receptor alpha	7	0	0	7
farnesoid X nuclear receptor	4	0	0	4
G	3	0	0	3
cytochrome P450 2D6	5	0	0	5
bromodomain adjacent to zinc finger domain 2B	3	0	0	3
peroxisome proliferator activated receptor gamma	6	0	0	6
vitamin D (1,25- dihydroxyvitamin D3) receptor	7	0	0	7
caspase-3	2	0	0	2
TPA: protein transporter TIM10	0	1	0	1
activating transcription factor 6	5	0	0	5
beta-2 adrenergic receptor	1	0	0	1
lysosomal alpha-glucosidase preproprotein	1	0	0	1
cellular tumor antigen p53 isoform a	4	0	0	4
polyunsaturated fatty acid lipoxygenase ALOX12	1	0	0	1
thyroid hormone receptor beta isoform 2	6	0	0	6
heat shock protein beta-1	4	0	0	4
importin subunit beta-1 isoform 1	1	0	0	1
snurportin-1	1	0	0	1
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
urokinase-type plasminogen activator precursor	2	0	0	2
plasminogen precursor	2	0	0	2
urokinase plasminogen activator surface receptor precursor	2	0	0	2
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	2	0	0	2
lamin isoform A-delta10	5	0	0	5
Polyunsaturated fatty acid lipoxygenase ALOX15B	3	0	0	3
HLA class I histocompatibility antigen, B alpha chain	3	0	0	3
Integrin beta-3	3	1	0	4
Integrin alpha-IIb	3	0	0	3
Neuronal acetylcholine receptor subunit alpha-4	1	0	0	1
Neuronal acetylcholine receptor subunit beta-2	1	0	0	1
Alpha-synuclein	3	0	0	3
Histamine H2 receptor	3	0	0	3
Spike glycoprotein	3	0	1	4
Rap guanine nucleotide exchange factor 4	1	0	0	1
Inositol hexakisphosphate kinase 1	3	0	0	3
cytochrome P450 2C9, partial	3	0	0	3
Chain A, HADH2 protein	1	0	0	1
Chain B, HADH2 protein	1	0	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	2	0	0	2
interleukin 8	1	0	0	1
acetylcholinesterase	3	0	0	3
ATAD5 protein, partial	3	0	0	3
thyroid stimulating hormone receptor	2	0	0	2
progesterone receptor	3	0	0	3
regulator of G-protein signaling 4	3	0	0	3
glucocorticoid receptor [Homo sapiens]	3	0	0	3
67.9K protein	3	0	0	3
peroxisome proliferator-activated receptor delta	4	0	0	4
v-jun sarcoma virus 17 oncogene homolog (avian)	3	0	0	3
Histone H2A.x	4	0	0	4
vitamin D3 receptor isoform VDRA	3	0	0	3
thyroid hormone receptor beta isoform a	2	0	0	2
ubiquitin carboxyl-terminal hydrolase 2 isoform a	2	0	0	2
serine/threonine-protein kinase PLK1	1	0	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	1	0	0	1
survival motor neuron protein isoform d	2	0	0	2
high affinity choline transporter 1 isoform a	0	1	0	1
lethal factor (plasmid)	2	0	0	2
neuropeptide S receptor isoform A	2	0	0	2
5-hydroxytryptamine receptor 4	0	4	0	4
Nuclear receptor subfamily 1 group I member 2	0	1	0	1
Voltage-dependent calcium channel gamma-2 subunit	3	0	0	3
Carbonic anhydrase 1	0	2	0	2
Carbonic anhydrase 2	0	2	0	2
Estrogen receptor	0	4	2	7
Glucocorticoid receptor	0	2	0	2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
Tyrosine-protein kinase Fyn	0	3	0	3
Glycine receptor subunit alpha-1	0	2	0	2
Aldo-keto reductase family 1 member B1	0	4	0	4
Beta-1 adrenergic receptor	0	4	0	4
Alpha-2A adrenergic receptor	0	4	0	4
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	2
Adenosine receptor A3	0	4	0	4
Muscarinic acetylcholine receptor M1	0	4	0	4
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
D(2) dopamine receptor	0	4	0	4
Androgen receptor	0	3	0	3
Alpha-1B adrenergic receptor	0	4	0	4
Alpha-2B adrenergic receptor	0	4	0	4
Alpha-2C adrenergic receptor	0	2	0	2
Glutamate receptor 2	3	0	0	3
Muscarinic acetylcholine receptor M3	0	4	0	4
Glycine receptor subunit beta	0	2	0	2
Substance-K receptor	0	6	0	6
D(1A) dopamine receptor	0	4	0	4
Acetylcholinesterase	0	1	0	1
Glycine receptor subunit alpha-2	0	2	0	2
Prostaglandin G/H synthase 1	0	2	0	2
Sodium-dependent noradrenaline transporter	0	4	0	4
Glycine receptor subunit alpha-3	0	2	0	2
Alpha-1D adrenergic receptor	0	6	0	6
5-hydroxytryptamine receptor 2A	0	4	0	4
5-hydroxytryptamine receptor 2C	0	4	0	4
Adenosine receptor A2a	0	6	0	6
Adenosine receptor A1	0	4	0	4
Sodium-dependent serotonin transporter	0	4	0	4
Mu-type opioid receptor	0	4	0	4
D(3) dopamine receptor	0	4	0	4
Vasopressin V1a receptor	0	2	0	2
Delta-type opioid receptor	0	6	0	6
Kappa-type opioid receptor	0	4	0	4
5-hydroxytryptamine receptor 2B	0	4	0	4
Alpha-1A adrenergic receptor	0	4	0	4
5-hydroxytryptamine receptor 6	0	4	0	4
Estrogen-related receptor gamma	0	1	1	2
Disintegrin and metalloproteinase domain-containing protein 17	1	0	0	1
Inositol monophosphatase 1	2	0	0	2
Sodium-dependent dopamine transporter	0	4	0	4
Aldehyde oxidase	0	1	0	1
TAR DNA-binding protein 43	1	0	0	1
UDP-glucose 4-epimerase	0	1	0	1
Mitogen-activated protein kinase 14	0	1	0	1
Estrogen receptor beta	0	4	2	6
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	1	0	1
Cysteinyl leukotriene receptor 1	0	2	0	2
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	1	0	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	1	0	0	1
Chain A, ATP-DEPENDENT DNA HELICASE Q1	1	0	0	1
Genome polyprotein	0	1	1	2
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
phosphopantetheinyl transferase	3	0	0	3
SMAD family member 2	3	0	0	3
Fumarate hydratase	2	0	0	2
SMAD family member 3	3	0	0	3
hypothetical protein, conserved	1	0	0	1
polyprotein	2	0	0	2
aryl hydrocarbon receptor	3	0	0	3
thyrotropin-releasing hormone receptor	3	0	0	3
Bloom syndrome protein isoform 1	2	0	0	2
eyes absent homolog 2 isoform a	1	0	0	1
lethal(3)malignant brain tumor-like protein 1 isoform I	1	0	0	1
DNA polymerase kappa isoform 1	1	0	0	1
histone acetyltransferase KAT2A isoform 1	2	0	0	2
relaxin receptor 1 isoform 1	1	0	0	1
Flavin reductase (NADPH)	0	0	1	1
large T antigen	0	1	0	1
EWS/FLI fusion protein	2	0	0	2
DNA polymerase beta	1	0	0	1
Histamine H2 receptor	0	4	0	4
7,8-dihydro-8-oxoguanine triphosphatase	0	1	0	1
Toll-like receptor 8	0	0	1	1
Toll-like receptor 7	0	0	1	1
Potassium voltage-gated channel subfamily H member 2	0	3	0	3
HLA class I histocompatibility antigen, A alpha chain	0	1	0	1
5-hydroxytryptamine receptor 2C	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	0	1
5-hydroxytryptamine receptor 2B	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
Carbonic anhydrase 4	0	1	0	1
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Carbonic anhydrase 9	0	1	0	1
Genome polyprotein	0	1	0	1
pregnane X receptor	1	0	0	1
nuclear receptor subfamily 1, group I, member 2	2	0	0	2
NPC intracellular cholesterol transporter 1 precursor	2	0	0	2
Tyrosine-protein kinase ABL1	0	1	0	1
Epidermal growth factor receptor	0	2	0	2
Tubulin alpha-1A chain	0	0	1	2
Tubulin beta chain	0	0	1	1
Tubulin beta-4A chain	0	1	1	3
Receptor tyrosine-protein kinase erbB-2	0	2	0	2
Integrin alpha-V	0	1	0	1
Tubulin beta chain	0	1	1	3
ATP-dependent translocase ABCB1	0	3	1	6
60 kDa chaperonin	0	1	0	1
Tubulin alpha-3C chain	0	1	1	3
Botulinum neurotoxin type A	0	1	0	1
Apoptosis regulator Bcl-2	0	1	0	1
60 kDa heat shock protein, mitochondrial	0	1	0	1
Fibroblast growth factor receptor 1	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	1	0	1
UDP-glucuronosyltransferase 2B7	0	1	0	1
UDP-glucuronosyltransferase 1-6	0	1	0	1
ATP-dependent translocase ABCB1	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	1	0	1
UDP-glucuronosyltransferase 1A4	0	1	0	2
Serum paraoxonase/arylesterase 1	0	1	0	1
Cholecystokinin receptor type A	0	2	0	2
Melanocortin receptor 5	0	4	0	4
UDP-glucuronosyltransferase 2B10	0	1	0	1
10 kDa heat shock protein, mitochondrial	0	1	0	1
Tubulin alpha-1B chain	0	1	1	3
Tubulin alpha-4A chain	0	1	1	3
Tubulin beta-4B chain	0	1	1	3
Bcl-2-like protein 1	0	1	0	1
Tyrosine-protein kinase Mer	0	1	0	1
Tubulin beta-3 chain	0	2	1	4
Tubulin beta-2A chain	0	1	1	3
Thiosulfate sulfurtransferase	0	1	0	1
Beta-tubulin	0	1	0	1
Tubulin beta-8 chain	0	1	1	3
60 kDa chaperonin	0	1	0	1
Tubulin beta-2B chain	0	0	1	3
Tubulin alpha-3E chain	0	1	1	3
Tubulin alpha-1A chain	0	1	1	3
10 kDa chaperonin	0	1	0	1
Similar to alpha-tubulin isoform 1	0	0	1	3
Similar to alpha-tubulin isoform 1	0	0	0	2
Tubulin alpha-1C chain	0	1	1	3
Tubulin beta-6 chain	0	1	1	3
Tubulin beta-2B chain	0	1	1	3
Tubulin beta-1 chain	0	1	1	3
Nucleotide-binding oligomerization domain-containing protein 2	0	1	0	1
Solute carrier organic anion transporter family member 1B3	0	2	0	2
Solute carrier organic anion transporter family member 1B1	0	2	0	2
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b	0	0	1	1
M-phase phosphoprotein 8	2	0	0	2
muscleblind-like protein 1 isoform 1	1	0	0	1
muscarinic acetylcholine receptor M1	1	0	0	1
Bile salt export pump	0	1	0	1
Chain A, CES1 protein	0	1	0	1
apical membrane antigen 1, AMA1	1	0	0	1
DNA polymerase III, partial	1	0	0	1
glucocerebrosidase	1	0	0	1
Caspase-7	1	0	0	1
Spike glycoprotein	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
interferon gamma precursor	0	0	0	1
D(1A) dopamine receptor	1	0	0	1
chromobox protein homolog 1	1	0	0	1
caspase-3	1	0	0	1
ubiquitin-conjugating enzyme E2 N	0	1	0	1
ras-related protein Rab-9A	1	0	0	1
serine/threonine-protein kinase mTOR isoform 1	1	0	0	1
streptokinase A precursor	0	0	1	1
Transmembrane protease serine 2	0	0	1	1
Serine/threonine-protein kinase D3	0	1	0	1
Lysosomal acid glucosylceramidase	0	0	1	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C alpha type	0	1	0	1
Protein kinase C beta type	0	1	0	1
Estrogen receptor	0	0	1	2
Tyrosine-protein kinase Lck	0	1	0	1
Progesterone receptor	0	1	0	1
Procathepsin L	0	0	1	1
Muscarinic acetylcholine receptor M2	0	2	0	2
Muscarinic acetylcholine receptor M4	0	2	0	2
Muscarinic acetylcholine receptor M5	0	2	0	2
Protein kinase C delta type	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
Replicase polyprotein 1a	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Steroid hormone receptor ERR1	0	1	0	1
Transcriptional activator protein LuxR	0	1	0	1
Angiotensin-converting enzyme	0	2	0	2
Beta-3 adrenergic receptor	0	2	0	2
Protein kinase C alpha type	0	1	0	1
5-hydroxytryptamine receptor 1A	0	2	0	2
Cytochrome P450 2B6	0	1	0	1
D(4) dopamine receptor	0	2	0	2
Protein kinase C eta type	0	1	0	1
Substance-P receptor	0	2	0	2
5-hydroxytryptamine receptor 1B	0	2	0	2
B2 bradykinin receptor	0	2	0	2
Melanocortin receptor 4	0	2	0	2
C-8 sterol isomerase	0	1	0	1
Protein kinase C iota type	0	1	0	1
Melanocortin receptor 3	0	2	0	2
D(1A) dopamine receptor	1	0	0	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C beta type	0	1	0	1
Phospholipase D1	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C theta type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
Protein kinase C delta type	0	1	0	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Platelet-activating factor acetylhydrolase	0	1	0	1
Phospholipase D1	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	2	1	3
Serine/threonine-protein kinase D1	0	1	0	1
Estrogen receptor beta	0	0	1	2
Protein kinase C eta type	0	1	0	1
Nuclear receptor subfamily 3 group C member 3	0	2	0	2
ATPase family AAA domain-containing protein 5	1	0	0	1
Ataxin-2	1	0	0	1
Sigma non-opioid intracellular receptor 1	0	2	0	2
Emopamil-binding protein-like	0	1	0	1
Angiotensin-converting enzyme 2	0	0	1	1
7-dehydrocholesterol reductase	0	1	1	2
Protein kinase C theta type	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(10)

Research Excerpts

Overview

Context

Treatment

Research

Studies (59)

Protein Targets (397)

Mammary Paget Disease

Synonyms(10)

Research Excerpts

Overview

Context

Treatment

Research

Studies (59)

Drugs Studied (29)

Protein Targets (397)