MELAS Syndrome

A mitochondrial disorder characterized by focal or generalized seizures, episodes of transient or persistent neurologic dysfunction resembling strokes, and ragged-red fibers on muscle biopsy. Affected individuals tend to be normal at birth through early childhood, then experience growth failure, episodic vomiting, and recurrent cerebral insults resulting in visual loss and hemiparesis. The cortical lesions tend to occur in the parietal and occipital lobes and are not associated with vascular occlusion. VASCULAR HEADACHE is frequently associated and the disorder tends to be familial. (From Joynt, Clinical Neurology, 1992, Ch56, p117)

Synonym
MELAS Syndrome

Excerpt	Reference
"The MELAS syndrome is thus another condition to add to the list of various chronic refractory disorders that improve considerably after dextroamphetamine therapy."	( Check, JH; Mitchell-Williams, J; Potestio, CP, 2014)
"NO deficiency in MELAS syndrome is likely to be multifactorial in origin with the decreased availability of the NO precursors, arginine and citrulline, playing a major role."	( Almannai, M; Chanprasert, S; Craigen, WJ; El-Hattab, AW; Emrick, LT; Hsu, JW; Jahoor, F; Scaglia, F, 2016)
"MELAS syndrome is a severe mitochondrial disease mainly due to the m."	( Belal, S; Benyahia, R; Bonneau, D; Bris, C; Chevrollier, A; Desquiret-Dumas, V; Frey, S; Geffroy, G; Gueguen, N; Henrion, D; Inisan, A; Lenaers, G; Letournel, F; Procaccio, V; Renaud, A; Reynier, P, 2018)

Excerpt	Reference
"Many of the accepted therapies used in treating MELAS syndrome have been identified through a small number of clinical trials or isolated case reports."	( Santa, KM, 2010)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	1 (0.30)	23.3326
1990's	69 (20.78)	12.5806
2000's	126 (37.95)	18.1394
2010's	101 (30.42)	28.8240
2020's	35 (10.54)	9.53

Drug	Relationship Strength	Studies	Trials
gamma-aminobutyric acid	low	1	0
acetone	low	1	0
adenine	low	10	0
carnitine	low	3	0
choline	low	6	0
3-hydroxybutyric acid	low	2	0
n(g),n(g')-dimethyl-l-arginine	medium	1	1
creatine	low	10	0
cytosine	low	3	0
lactic acid	medium	45	4
glycine	low	4	0
glycerol	low	1	0
inositol	low	3	0
niacinamide	low	4	0
4-aminobenzoic acid	low	1	0
pyruvic acid	medium	8	1
succinic acid	low	2	0
taurine	medium	7	1
thiamine	medium	3	1
thymine	low	3	0
uric acid	low	1	0
3-nitropropionic acid	low	1	0
phenytoin	low	1	0
acetazolamide	medium	5	1
theophylline	low	1	0
antipyrine	low	2	0
carbamazepine	low	2	0
dapi	low	1	0
diazepam	low	1	0
dipyridamole	low	1	0
distigmine	low	1	0
valproic acid	low	6	0
eicosapentaenoic acid ethyl ester	low	1	0
fentanyl	low	2	0
flumazenil	low	1	0
fluoxetine	low	1	0
haloperidol	low	1	0
ethidium	low	2	0
lidocaine	low	1	0
iofetamine	low	5	0
lamotrigine	low	2	0
beta-lapachone	low	1	0
lorazepam	low	1	0
losartan	low	1	0
edaravone	low	2	0
metformin	low	4	0
midazolam	low	3	0
molsidomine	low	1	0
pioglitazone	low	1	0
propofol	low	3	0
linsidomine	low	1	0
succinylcholine	low	2	0
sumatriptan	low	1	0
thiotepa	low	1	0
prednisolone	low	3	0
dextroamphetamine	low	1	0
alanine	medium	6	1
chloramphenicol	low	1	0
aspartic acid	low	11	0
glutamine	low	5	0
apomorphine	low	1	0
adenosine diphosphate	low	2	0
uridine	low	3	0
galactose	low	2	0
tyrosine	low	1	0
leucine	low	1	0
phenylalanine	low	1	0
ornithine	medium	1	1
histidine	low	1	0
valine	low	2	0
tert-butylhydroperoxide	low	1	0
methylprednisolone	medium	1	1
rotenone	low	1	0
thiamine pyrophosphate	medium	1	1
2-hydroxybutyric acid	medium	1	1
acetylcysteine	low	2	0
d-alpha tocopherol	medium	3	1
gadolinium	low	1	0
gold	low	1	0
xenon	low	2	0
magnesium sulfate	low	1	0
phenyl acetate	medium	2	1
glutamic acid	low	6	0
vecuronium bromide	low	1	0
atracurium	low	1	0
fomesafen	low	1	0
lovastatin	low	2	0
simvastatin	low	1	0
remifentanil	low	1	0
3-iodobenzylguanidine	low	1	0
adenosine	low	5	0
cisatracurium	low	1	0
n-acetylaspartic acid	low	9	0
xenon radioisotopes	low	2	0
n-acetylvaline	low	1	0
fluorodeoxyglucose f18	medium	4	1
oxazolidin-2-one	low	1	0
fibrinogen	low	1	0
homocysteine	low	1	0
deoxyglucose	low	2	0
iodofiltic acid	low	1	0
n,n-dimethylarginine	medium	1	1
dihydroethidium	low	1	0
thrombin receptor peptide sfllrnp	low	1	0
tetraphenylphosphonium	low	1	0
ropivacaine	low	1	0
lacosamide	low	1	0
3-nitrotyrosine	low	1	0
benzofurans	low	1	0
fibrin	low	1	0
rocuronium	low	1	0
linezolid	low	1	0
acetyl coenzyme a	low	1	0
eicosapentaenoic acid	low	1	0
riboflavin	medium	4	1
thiouridine	low	3	0
2-thiouridine	low	2	0
prucalopride	low	1	0
naphthoquinones	low	1	0
vitamin k semiquinone radical	medium	1	1
coenzyme q10	medium	9	1
isotretinoin	low	1	0
levetiracetam	low	2	0
sirolimus	low	2	0
cysteine	low	1	0
phosphorus	low	2	0
everolimus	low	1	0
i(3)so3-galactosylceramide	low	1	0
beta-escin	low	1	0
gadolinium dtpa	low	2	0
bentiromide	low	1	0
phosphocreatine	medium	6	1
2-carbomethoxy-8-(3-fluoropropyl)-3-(4-iodophenyl)tropane	low	1	0
ro 16-0154	low	1	0
technetium tc 99m exametazime	low	8	0
jaw	low	1	0
nad	low	4	0
cytochrome c-t	medium	2	1
humanin	low	3	0
glucagon	low	1	0
oligonucleotides	low	1	0
anticodon	low	6	0
c-peptide	medium	3	1
ubiquinone	medium	18	2
piperidines	low	1	0
heme	low	1	0
ascorbic acid	medium	4	1
salicylates	low	1	0
bassianolide	low	1	0
cyclosporine	low	1	0
flavin mononucleotide	medium	1	1
5-taurinomethyluridine	low	2	0
cyclic gmp	medium	1	1
deoxyguanosine	low	1	0
deoxyguanosine triphosphate	low	1	0
guanine	low	11	0
guanosine	low	2	0
2,2'-(hydroxynitrosohydrazono)bis-ethanamine	low	1	0
8-hydroxy-2'-deoxyguanosine	low	1	0
phosphocreatinine	medium	1	1
eye	low	1	0
phosphorus radioisotopes	low	2	0

Protein Targets (1,588)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Sodium-dependent dopamine transporter	0	7	2	9
Monocarboxylate transporter 4	0	0	0	2
Chain A, RNA polymerase	0	0	1	1
Protein skinhead-1	0	1	0	1
Monocarboxylate transporter 2	0	2	0	2
Solute carrier family 22 member 20	0	3	0	3
Solute carrier family 22 member 6	0	3	0	3
dopamine D1 receptor	3	0	0	3
thioredoxin reductase	24	0	0	24
GLS protein	14	0	0	14
Thrombopoietin	5	0	0	5
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	8	0	0	8
cytochrome P450 2D6 isoform 1	7	0	0	7
cytochrome P450 2C19 precursor	10	0	0	10
ras-related protein Rab-9A	4	0	0	4
histone acetyltransferase KAT2A isoform 1	11	0	0	11
lethal factor (plasmid)	13	0	0	13
POU domain, class 2, transcription factor 1	0	0	0	1
Spike glycoprotein	14	0	0	14
ATP-dependent phosphofructokinase	13	0	0	13
acetylcholinesterase	15	0	0	15
RAR-related orphan receptor gamma	24	0	0	24
GLI family zinc finger 3	29	0	0	29
AR protein	39	0	0	39
progesterone receptor	17	0	0	17
glucocorticoid receptor [Homo sapiens]	32	0	0	32
retinoic acid nuclear receptor alpha variant 1	31	0	0	31
retinoid X nuclear receptor alpha	20	0	0	20
estrogen-related nuclear receptor alpha	34	0	0	34
estrogen nuclear receptor alpha	46	0	0	46
vitamin D (1,25- dihydroxyvitamin D3) receptor	18	0	0	18
euchromatic histone-lysine N-methyltransferase 2	39	0	0	39
aryl hydrocarbon receptor	10	0	0	10
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	21	0	0	21
thyrotropin-releasing hormone receptor	4	0	0	4
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	16	0	0	16
v-jun sarcoma virus 17 oncogene homolog (avian)	17	0	0	17
Histone H2A.x	13	0	0	13
Bloom syndrome protein isoform 1	16	0	0	16
hemoglobin subunit beta	2	0	0	2
chromobox protein homolog 1	14	0	0	14
heat shock protein beta-1	14	0	0	14
DNA polymerase iota isoform a (long)	14	0	0	14
geminin	39	0	0	39
muscarinic acetylcholine receptor M1	13	0	0	13
lamin isoform A-delta10	30	0	0	30
Voltage-dependent calcium channel gamma-2 subunit	13	0	0	13
Cellular tumor antigen p53	28	0	0	28
Delta-aminolevulinic acid dehydratase	0	2	0	2
Glutamate receptor 2	13	2	1	16
Isocitrate lyase 1	0	1	0	1
Isocitrate lyase	0	1	0	1
TAR DNA-binding protein 43	9	0	0	9
Isocitrate lyase	0	1	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	7	0	0	7
Chain A, JmjC domain-containing histone demethylation protein 3A	3	0	0	3
phosphopantetheinyl transferase	12	0	0	12
bromodomain adjacent to zinc finger domain 2B	7	0	0	7
pyruvate kinase PKM isoform a	1	0	0	1
Glycoprotein hormones alpha chain	1	0	0	1
Guanine nucleotide-binding protein G	3	0	0	3
Tubulin--tyrosine ligase	0	2	0	2
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	22	0	0	22
Genome polyprotein	0	0	1	1
USP1 protein, partial	16	0	0	16
thyroid stimulating hormone receptor	12	0	0	12
transcriptional regulator ERG isoform 3	5	0	0	5
Polyphenol oxidase 2	0	2	0	3
Thiopurine S-methyltransferase	0	1	0	1
Succinate-semialdehyde dehydrogenase, mitochondrial	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	2
Cytochrome P450 1B1	0	2	0	2
Dihydropteroate synthase	0	0	1	1
Chain A, Toluene-4-monooxygenase system protein A	0	1	0	1
Chain A, Avidin	0	0	2	2
Chain A, Avidin	0	0	2	2
Chain B, Avidin	0	0	2	2
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	13	0	0	13
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Beta-lactamase	9	0	0	9
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Class Iii Chitinase Chia1	0	1	0	1
Chain A, Carbonic anhydrase 13	0	1	0	1
Chain A, Carbonic anhydrase II	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase	0	1	0	1
Chain B, Carbonic anhydrase	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	1	0	1
GALC protein	4	0	0	4
nuclear receptor subfamily 1, group I, member 3	20	0	0	20
cytochrome P450 family 3 subfamily A polypeptide 4	24	0	0	24
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
arylsulfatase A	14	0	0	14
Carbonic anhydrase	0	1	0	1
thyroid hormone receptor beta isoform a	16	0	0	16
nuclear factor erythroid 2-related factor 2 isoform 1	26	0	0	26
peripheral myelin protein 22	18	0	0	18
survival motor neuron protein isoform d	10	0	0	10
muscleblind-like protein 1 isoform 1	5	0	0	5
Gamma-aminobutyric acid receptor subunit pi	13	10	2	25
ATP-binding cassette sub-family C member 3	0	28	0	28
Multidrug resistance-associated protein 4	0	28	0	29
Carbonic anhydrase	0	1	0	1
Solute carrier family 22 member 6	0	2	0	2
Carbonic anhydrase 12	0	3	1	9
Prolyl endopeptidase	0	1	0	1
Carbonic anhydrase-related protein 11	0	1	0	2
Bile salt export pump	0	38	0	38
Glycogen phosphorylase, muscle form	0	1	0	1
Renin	0	3	0	3
Carbonic anhydrase 1	0	6	1	19
Carbonic anhydrase 2	0	7	1	19
Carbonic anhydrase 2	0	2	0	2
Cytochrome P450 1A2	0	3	0	4
Carbonic anhydrase 3	0	3	1	9
Cathepsin B	0	1	0	1
Cytochrome P450 3A4	0	9	1	13
Steryl-sulfatase	0	2	0	2
5-hydroxytryptamine receptor 2C	0	9	1	10
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	2
Cytochrome P450 2C8	0	2	0	2
Cytochrome P450 2D6	0	4	0	5
Cytochrome P450 2A6	0	2	0	2
Cytochrome P450 2C9	0	11	0	12
5-hydroxytryptamine receptor 2A	0	9	1	10
Androgen receptor	0	6	0	6
Gamma-aminobutyric acid receptor subunit beta-1	13	10	2	25
Translocator protein	0	3	1	5
Gamma-aminobutyric acid receptor subunit delta	13	10	2	25
Gamma-aminobutyric acid receptor subunit gamma-2	13	10	3	26
Gamma-aminobutyric acid receptor subunit alpha-5	13	10	2	25
Gamma-aminobutyric acid receptor subunit alpha-3	13	10	2	25
Cannabinoid receptor 1	0	1	0	1
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
Cytochrome P450 2B6	0	2	1	3
Carbonic anhydrase 4	0	4	1	9
Carbonic anhydrase 6	0	4	1	9
Gamma-aminobutyric acid receptor subunit gamma-1	13	10	2	25
Gamma-aminobutyric acid receptor subunit alpha-2	13	10	2	25
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Adenosine receptor A1	0	6	1	11
Serum paraoxonase/arylesterase 1	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	2
Gamma-aminobutyric acid receptor subunit alpha-4	13	10	2	25
Gamma-aminobutyric acid receptor subunit gamma-3	13	10	2	25
Endochitinase	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	13	10	2	25
Adenosine receptor A2a	0	4	1	10
5-hydroxytryptamine receptor 2B	0	8	1	9
Sodium-dependent serotonin transporter	0	4	1	5
Delta-type opioid receptor	0	3	0	3
Cytochrome P450 2C19	0	6	0	7
Delta-type opioid receptor	0	4	0	4
Mu-type opioid receptor	0	5	1	6
Carbonic anhydrase 5A, mitochondrial	0	3	1	9
Carbonic anhydrase	0	2	0	5
Kappa-type opioid receptor	0	4	0	4
Carbonic anhydrase 7	0	3	1	8
Carbonic anhydrase	0	1	0	1
D(1A) dopamine receptor	3	2	0	5
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Carbonic anhydrase	0	1	0	4
D(2) dopamine receptor	0	9	2	11
Gamma-aminobutyric acid receptor subunit alpha-1	13	10	3	26
Gamma-aminobutyric acid receptor subunit beta-3	13	10	2	25
Gamma-aminobutyric acid receptor subunit beta-2	13	10	3	26
Cholinesterase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Mu-type opioid receptor	0	3	0	3
Fatty-acid amide hydrolase 1	0	4	0	4
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	7	2	12
Squalene synthase	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-7	0	4	0	4
Carbonic anhydrase 9	0	3	1	9
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	4
Carbonic anhydrase 3	0	1	0	1
Carbonic anhydrase	0	1	0	5
Carbonic anhydrase	0	1	0	5
Carbonic anhydrase	0	1	0	1
Sigma intracellular receptor 2	0	3	0	3
Delta carbonic anhydrase	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	10	0	10
Renin	0	1	0	1
Carbonic anhydrase	0	1	0	4
Endochitinase A1	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	1
Carbonic anhydrase 13	0	3	1	7
GABA theta subunit	13	10	2	25
Canalicular multispecific organic anion transporter 1	0	25	0	25
Carbonic anhydrase 4	0	2	0	5
Carbonic anhydrase 15	0	3	0	7
Acidic mammalian chitinase	0	1	0	1
Carbonic anhydrase 13	0	2	0	5
Carbonic anhydrase 7	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	13	10	2	25
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 14	0	3	1	9
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 2, isoform A	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	3	1	9
TDP1 protein	36	0	0	36
thyroid hormone receptor beta isoform 2	24	0	0	24
N-alpha-acetyltransferase 50	0	0	1	1
Chain A, 2-oxoglutarate Oxygenase	7	0	0	7
Chain A, ATP-DEPENDENT DNA HELICASE Q1	6	0	0	6
15-lipoxygenase, partial	6	0	0	6
pregnane X receptor	4	0	0	4
NFKB1 protein, partial	6	0	0	6
Microtubule-associated protein tau	13	0	0	13
regulator of G-protein signaling 4	19	0	0	19
farnesoid X nuclear receptor	16	0	0	16
D(1A) dopamine receptor	8	0	0	8
flap endonuclease 1	14	0	0	14
Histone deacetylase 3	0	4	0	4
Histone deacetylase 4	0	4	0	4
Histone deacetylase 1	0	5	0	5
Histone deacetylase 7	0	4	0	4
Histone deacetylase 2	0	5	0	5
Polyamine deacetylase HDAC10	0	4	0	4
Histone deacetylase 11	0	4	0	4
Ataxin-2	17	0	0	17
Histone deacetylase 8	0	4	0	4
Histone deacetylase 6	0	5	0	5
Histone deacetylase 9	0	4	0	4
Histone deacetylase 5	0	4	0	4
Chain A, MTA/SAH nucleosidase	0	1	0	1
Chain A, Ribosome-inactivating protein alpha-trichosanthin	0	0	1	1
Chain A, Ricin A chain	0	0	1	1
Chain A, Ribosome-inactivating protein 3	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
pregnane X nuclear receptor	23	0	0	23
nuclear factor erythroid 2-related factor 2 isoform 2	12	0	0	13
importin subunit beta-1 isoform 1	4	0	0	4
snurportin-1	4	0	0	4
tumor susceptibility gene 101 protein	2	0	0	2
GTP-binding nuclear protein Ran isoform 1	3	0	0	3
Cyclin-dependent kinase 1	0	1	2	3
Heat shock protein HSP 90-beta	0	2	1	4
Xanthine dehydrogenase/oxidase	0	1	0	1
Protein mono-ADP-ribosyltransferase PARP15	0	2	0	2
Leucine-rich repeat serine/threonine-protein kinase 2	0	2	0	2
ATPase family AAA domain-containing protein 5	12	0	0	12
Chain A, Membrane lipoprotein tmpC	0	0	2	2
Chain A, Membrane lipoprotein tmpC	0	0	2	2
Chain A, Membrane lipoprotein tmpC	0	0	2	2
Chain A, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain B, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, tRNA (guanine-N(1)-)-methyltransferase	0	0	1	1
Chain A, Uncharacterized protein MJ0883	0	0	1	1
signal transducer and activator of transcription 6, interleukin-4 induced	1	0	0	1
NPYLR7B	0	0	4	4
IDH1	13	0	0	13
glycogen synthase kinase-3 beta isoform 1	0	0	1	1
mitogen-activated protein kinase 1	9	0	0	9
nuclear receptor ROR-gamma isoform 1	14	0	0	14
high affinity choline transporter 1 isoform a	0	1	0	1
Sodium/nucleoside cotransporter 1	0	4	0	4
Calcium dependent protein kinase	0	1	0	1
Mitogen-activated protein kinase kinase kinase 7	0	0	2	2
Sodium/nucleoside cotransporter 2	0	4	0	4
Rap guanine nucleotide exchange factor 3	5	0	0	5
Purine nucleoside phosphorylase	0	3	0	4
Epidermal growth factor receptor	0	1	2	3
Phosphoglycerate kinase 1	0	1	0	1
Adenosine deaminase	0	0	0	1
Avidin	0	0	1	1
Adenosine deaminase	0	0	0	1
Glyceraldehyde-3-phosphate dehydrogenase	0	2	0	2
Receptor tyrosine-protein kinase erbB-2	0	1	0	1
Insulin receptor	0	0	2	3
Phosphoglycerate kinase 2	0	1	0	1
Heat shock protein HSP 90-alpha	0	2	2	5
Platelet-derived growth factor receptor beta	0	0	2	3
Adenosine receptor A3	0	5	2	8
Heat shock 70 kDa protein 1A	0	2	1	3
Heat shock cognate 71 kDa protein	0	0	2	2
Fibroblast growth factor receptor 1	0	0	2	3
Inosine-5'-monophosphate dehydrogenase 2	0	1	2	3
Endoplasmin	0	1	1	3
Inosine-5'-monophosphate dehydrogenase 1	0	1	0	1
Fibroblast growth factor receptor 2	0	0	0	1
Fibroblast growth factor receptor 4	0	0	0	1
Fibroblast growth factor receptor 3	0	0	0	1
Streptavidin	0	0	1	1
Adenosylhomocysteinase	0	1	0	3
Adenosine receptor A3	0	2	0	2
Adenosine receptor A2a	0	3	4	9
Adenosine receptor A2b	0	1	1	4
Adenosine receptor A2b	0	2	1	4
Adenylate kinase 2, mitochondrial	0	1	0	1
Adenosine receptor A1	0	6	3	12
Adenylate kinase isoenzyme 1	0	1	0	1
Phosphatidylinositol 4-kinase alpha	0	4	0	5
Adenosine receptor A1	0	1	1	2
Adenosine kinase	0	0	2	3
Adenosine deaminase	0	0	0	1
Equilibrative nucleoside transporter 2	0	4	0	4
Phosphatidylinositol 4-kinase type 2-beta	0	4	0	5
Histone-lysine N-methyltransferase, H3 lysine-79 specific	0	1	0	1
Equilibrative nucleoside transporter 1	0	6	0	6
Phosphatidylinositol 4-kinase type 2-alpha	0	4	0	5
Solute carrier family 28 member 3	0	4	0	4
Adenosine kinase	0	1	0	2
Phosphatidylinositol 4-kinase beta	0	4	0	5
5-methylthioadenosine/S-adenosylhomocysteine deaminase	0	0	0	1
Adenosine transporter 1	0	0	0	1
Chain A, Heat Shock Protein 90	0	0	1	1
Chain A, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain B, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, Myosin Ie Heavy Chain	0	0	1	1
Chain A, Preprotein translocase secA	0	0	1	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Phosphoribosylformylglycinamidine synthase	0	1	0	1
Chain A, nucleoside diphosphate kinase A	0	0	1	1
Chain B, nucleoside diphosphate kinase A	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A, Kinesin-like protein KIF11	0	1	0	1
HPr kinase/phosphorylase	0	0	1	1
ATP-dependent molecular chaperone HSP82	0	0	0	1
2-dehydropantoate 2-reductase	0	1	1	2
Endoplasmic reticulum chaperone BiP	0	0	1	1
Pyruvate kinase PKM	0	0	0	1
Pyruvate kinase PKLR	0	0	0	1
Heat shock cognate 71 kDa protein	0	0	1	1
5'-nucleotidase	0	2	0	2
Mu-type opioid receptor	0	4	3	7
Delta-type opioid receptor	0	2	1	3
Kappa-type opioid receptor	0	2	1	3
Endoplasmin	0	1	1	2
P2Y purinoceptor 2	0	0	1	1
P2X purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2X purinoceptor 1	0	0	1	1
P2X purinoceptor 4	0	0	1	1
P2X purinoceptor 5	0	0	1	1
P2X purinoceptor 6	0	0	1	1
P2X purinoceptor 3	0	0	1	1
Inositol monophosphatase 1	8	0	0	8
Heat shock protein 75 kDa, mitochondrial	0	1	0	1
P2Y purinoceptor 6	0	0	1	1
P2Y purinoceptor 11	0	0	1	1
P2Y purinoceptor 12	0	0	1	1
Sensor protein kinase WalK	0	1	0	1
P2X purinoceptor 2	0	0	1	1
Alanine racemase, biosynthetic	0	0	0	1
5-hydroxytryptamine receptor 1D	0	2	1	7
Glutamate receptor ionotropic, NMDA 1	0	7	2	12
Proton-coupled amino acid transporter 1	0	6	0	7
Adenosine deaminase	0	0	0	1
ATAD5 protein, partial	10	0	0	10
67.9K protein	8	0	0	8
peroxisome proliferator-activated receptor delta	15	0	0	15
Cytochrome P450 2J2	0	5	0	5
Nicotinate phosphoribosyltransferase	0	1	0	1
Chain A, HADH2 protein	4	0	0	4
Chain B, HADH2 protein	4	0	0	4
Luciferase	10	0	0	10
hypoxia-inducible factor 1 alpha subunit	12	0	0	12
aldehyde dehydrogenase 1 family, member A1	17	0	0	17
estrogen receptor 2 (ER beta)	11	0	0	11
cytochrome P450 2D6	15	0	0	15
peroxisome proliferator activated receptor gamma	18	0	0	18
thyroid stimulating hormone receptor	9	0	0	9
cellular tumor antigen p53 isoform a	3	0	0	3
cytochrome P450 2C9 precursor	6	0	0	6
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	5	0	0	5
vitamin D3 receptor isoform VDRA	14	0	0	14
potassium voltage-gated channel subfamily H member 2 isoform d	14	0	0	14
cytochrome P450 3A4 isoform 1	13	0	0	13
Solute carrier family 22 member 1	0	7	0	10
Polyunsaturated fatty acid lipoxygenase ALOX15B	4	0	0	4
Integrin beta-3	3	0	1	4
Integrin alpha-IIb	3	0	1	4
5-hydroxytryptamine receptor 1A	0	7	2	9
Tryptophan 5-hydroxylase 1	0	1	0	1
D(2) dopamine receptor	0	8	3	15
Alpha-1B adrenergic receptor	0	9	0	9
D	0	5	0	5
D(3) dopamine receptor	0	5	0	5
5-hydroxytryptamine receptor 1A	0	11	3	14
Alpha-2B adrenergic receptor	0	4	0	4
D(2) dopamine receptor	0	4	0	4
D(1A) dopamine receptor	0	6	2	11
D(4) dopamine receptor	0	7	2	12
D(1B) dopamine receptor	0	4	0	6
Alpha-2C adrenergic receptor	0	4	0	4
Alpha-2A adrenergic receptor	0	4	0	4
Alpha-1D adrenergic receptor	0	7	0	7
D(1B) dopamine receptor	0	3	0	3
5-hydroxytryptamine receptor 2A	0	9	0	9
5-hydroxytryptamine receptor 1B	0	4	1	5
5-hydroxytryptamine receptor 1D	0	3	2	5
D(4) dopamine receptor	0	4	1	5
5-hydroxytryptamine receptor 1F	0	2	1	3
5-hydroxytryptamine receptor 6	0	1	1	2
5-hydroxytryptamine receptor 7	0	3	1	4
5-hydroxytryptamine receptor 5A	0	1	1	2
5-hydroxytryptamine receptor 5B	0	1	1	2
D(3) dopamine receptor	0	7	2	12
5-hydroxytryptamine receptor 3A	0	2	1	3
Alpha-1A adrenergic receptor	0	9	0	9
Histamine H2 receptor	6	0	0	7
5-hydroxytryptamine receptor 7	0	2	0	2
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
D	0	1	0	1
5-hydroxytryptamine receptor 4	0	1	2	3
D	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	7	0	7
5-hydroxytryptamine receptor 3B	0	2	1	3
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	3	3
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	3	3
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	3	3
alpha-galactosidase	2	0	0	2
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	2	0	3
Nitric oxide synthase, brain	0	2	0	3
Nitric oxide synthase, inducible	0	0	0	1
Nitric oxide synthase, inducible	0	0	1	3
Cationic amino acid transporter 3	0	1	0	1
Chain A, Hyaluronidase, phage associated	0	1	0	1
thioredoxin glutathione reductase	4	0	0	4
lethal(3)malignant brain tumor-like protein 1 isoform I	1	0	0	1
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	1	0	1
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	1	0	1
Alpha-2B adrenergic receptor	0	8	1	9
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	1	1	3
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
Chain A, Ferritin light chain	12	0	0	12
Metabotropic glutamate receptor 6	0	1	2	4
Excitatory amino acid transporter 4	0	2	0	2
Glutamate transporter homolog	0	0	1	1
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	2	0	2
Excitatory amino acid transporter 1	0	3	0	4
Excitatory amino acid transporter 2	0	3	0	4
Excitatory amino acid transporter 3	0	3	0	4
Glutamate receptor ionotropic, NMDA 2A	0	6	2	11
Glutamate receptor ionotropic, NMDA 2C	0	6	2	11
Metabotropic glutamate receptor 1	0	1	2	4
Metabotropic glutamate receptor 2	0	1	2	4
Carbonic anhydrase-like protein, putative	0	0	0	6
Glutamate receptor ionotropic, NMDA 2D	0	6	2	11
Glutamate receptor ionotropic, NMDA 3B	0	6	2	11
Glutamate receptor ionotropic, NMDA 3A	0	6	2	11
Amine oxidase [flavin-containing] A	0	1	1	2
Small conductance calcium-activated potassium channel protein 3	0	1	1	2
PPM1D protein	3	0	0	3
Smad3	6	0	0	6
EWS/FLI fusion protein	19	0	0	19
Lysine-specific demethylase 4E	0	3	0	3
Parkin	4	0	0	4
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	1	0	0	1
galactokinase	1	0	0	1
hexokinase-4 isoform 1	1	0	0	1
peripheral myelin protein 22 isoform 1	8	0	0	8
glucokinase regulatory protein	1	0	0	1
atrial natriuretic peptide receptor 2 precursor	3	0	0	3
serine/threonine-protein kinase mTOR isoform 1	5	0	0	5
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	5	0	0	5
DNA polymerase eta isoform 1	2	0	0	2
M-phase phosphoprotein 8	2	0	0	2
neuropeptide S receptor isoform A	4	0	0	4
Cocaine esterase	0	3	0	3
Tyrosyl-DNA phosphodiesterase 2	0	1	0	1
Interferon beta	18	0	0	18
Amyloid-beta precursor protein	1	2	0	3
60 kDa chaperonin	0	2	0	2
Replicase polyprotein 1ab	0	2	0	2
Replicase polyprotein 1ab	0	2	0	2
60 kDa heat shock protein, mitochondrial	0	2	0	2
Indoleamine 2,3-dioxygenase 1	0	2	0	2
NAD	0	1	0	1
NADPH--cytochrome P450 reductase	0	1	0	1
Protein kinase C alpha type	0	1	2	3
Nuclear factor NF-kappa-B p105 subunit	0	1	0	1
Protein-glutamine gamma-glutamyltransferase 2	0	1	0	1
Liver carboxylesterase 1	0	2	0	2
Caspase-1	0	1	0	1
M-phase inducer phosphatase 1	0	1	0	1
Alpha-synuclein	2	0	0	2
Tyrosine-protein kinase JAK3	0	1	0	1
10 kDa heat shock protein, mitochondrial	0	2	0	2
Nuclear factor NF-kappa-B p100 subunit	0	1	0	1
Transcription factor p65	0	1	0	1
Receptor-type tyrosine-protein phosphatase eta	0	1	0	1
Thiosulfate sulfurtransferase	0	2	0	2
Receptor protein-tyrosine kinase	0	1	0	1
60 kDa chaperonin	0	2	0	2
10 kDa chaperonin	0	2	0	2
Single-stranded DNA cytosine deaminase	2	0	0	2
Mucosa-associated lymphoid tissue lymphoma translocation protein 1	0	1	0	1
phosphoglycerate kinase	1	0	0	1
Vpr	2	0	0	2
Bile salt export pump	0	4	0	4
Albumin	0	0	4	4
Major prion protein	0	0	2	2
Sodium channel protein type 1 subunit alpha	0	4	0	4
Sodium channel protein type 2 subunit alpha	0	4	0	4
Sodium channel protein type 3 subunit alpha	0	4	0	4
UDP-glucuronosyltransferase 2B7	0	3	0	7
Sodium channel protein type 4 subunit alpha	0	5	0	8
Potassium voltage-gated channel subfamily H member 2	0	13	0	13
Sodium channel protein type 9 subunit alpha	0	7	0	7
Frizzled-8	0	0	1	1
P2X purinoceptor 4	0	1	0	1
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 16	0	0	0	1
Solute carrier family 22 member 21	0	0	0	1
Solute carrier family 22 member 5	0	0	0	1
interleukin 8	2	0	0	2
G	16	0	0	16
activating transcription factor 6	11	0	0	11
streptokinase A precursor	0	0	2	2
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
HLA class I histocompatibility antigen, B alpha chain	16	0	0	16
30S ribosomal protein S6	0	2	0	2
30S ribosomal protein S7	0	2	0	2
50S ribosomal protein L15	0	2	0	2
50S ribosomal protein L10	0	2	0	2
50S ribosomal protein L11	0	2	0	2
50S ribosomal protein L7/L12	0	2	0	2
50S ribosomal protein L19	0	2	0	2
50S ribosomal protein L1	0	2	0	2
50S ribosomal protein L20	0	2	0	2
50S ribosomal protein L27	0	2	0	2
50S ribosomal protein L28	0	2	0	2
50S ribosomal protein L29	0	2	0	2
50S ribosomal protein L31	0	2	0	2
50S ribosomal protein L31 type B	0	2	0	2
50S ribosomal protein L32	0	2	0	2
50S ribosomal protein L33	0	2	0	2
50S ribosomal protein L34	0	2	0	2
50S ribosomal protein L35	0	2	0	2
50S ribosomal protein L36	0	2	0	2
30S ribosomal protein S10	0	2	0	2
30S ribosomal protein S11	0	2	0	2
30S ribosomal protein S12	0	2	0	2
30S ribosomal protein S13	0	2	0	2
30S ribosomal protein S16	0	2	0	2
30S ribosomal protein S18	0	2	0	2
30S ribosomal protein S19	0	2	0	2
30S ribosomal protein S20	0	2	0	2
30S ribosomal protein S2	0	2	0	2
30S ribosomal protein S3	0	2	0	2
30S ribosomal protein S4	0	2	0	2
30S ribosomal protein S5	0	2	0	2
30S ribosomal protein S8	0	2	0	2
30S ribosomal protein S9	0	2	0	2
50S ribosomal protein L13	0	2	0	2
50S ribosomal protein L14	0	2	0	2
50S ribosomal protein L16	0	2	0	2
50S ribosomal protein L23	0	2	0	2
30S ribosomal protein S15	0	2	0	2
50S ribosomal protein L17	0	2	0	2
50S ribosomal protein L21	0	2	0	2
50S ribosomal protein L30	0	2	0	2
50S ribosomal protein L6	0	2	0	2
30S ribosomal protein S14	0	2	0	2
30S ribosomal protein S17	0	2	0	2
30S ribosomal protein S1	0	2	0	2
50S ribosomal protein L18	0	2	0	2
50S ribosomal protein L2	0	2	0	2
50S ribosomal protein L3	0	2	0	2
50S ribosomal protein L24	0	2	0	2
50S ribosomal protein L4	0	2	0	2
50S ribosomal protein L22	0	2	0	2
50S ribosomal protein L5	0	2	0	2
30S ribosomal protein S21	0	2	0	2
50S ribosomal protein L25	0	2	0	2
50S ribosomal protein L36 2	0	2	0	2
Inositol hexakisphosphate kinase 1	16	0	0	16
Methionine--tRNA ligase, mitochondrial	0	0	1	1
cytochrome P450 2C9, partial	16	0	0	16
Chain A, Acetylcholinesterase	0	0	2	2
Chain A, Acetylcholinesterase	0	0	2	2
Chain A, Acetylcholinesterase	0	0	2	2
Chain A, Acetylcholinesterase	0	0	2	2
Chain A, Acetylcholinesterase	0	0	2	2
Chain A, Acetylcholinesterase	0	0	2	2
Chain A, Acetylcholinesterase	0	0	2	2
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein	0	0	1	1
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Choline-binding protein	0	0	1	1
Solute carrier family 22 member 1	0	1	0	2
Solute carrier family 22 member 2	0	3	0	4
Solute carrier family 22 member 2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-3	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	1	3	0	4
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	1	3	0	4
Neuronal acetylcholine receptor subunit beta-3	0	1	0	1
Neuronal acetylcholine receptor subunit beta-4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-5	0	1	0	1
Acetylcholinesterase	0	2	0	2
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Choline O-acetyltransferase	0	0	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-9	0	1	0	1
Solute carrier family 22 member 1	0	2	0	4
High affinity choline transporter 1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-10	0	1	0	1
Solute carrier family 22 member 2	0	2	0	3
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	3	0	4
General amino-acid permease GAP1	0	0	0	1
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Phosphodiesterase	0	3	0	3
Multidrug resistance-associated protein 5	0	1	0	2
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	4	0	4
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	4	0	4
Deoxycytidine kinase	0	0	0	1
Glutathione S-transferase P	0	1	0	1
Alpha-tocopherol transfer protein	0	0	1	1
Prothrombin	0	1	0	1
Glandular kallikrein	0	1	0	1
Cell division protein FtsZ	0	0	1	2
Thymidine kinase, cytosolic	0	1	0	2
Deoxycytidine kinase	0	0	2	3
AAA family ATPase	0	0	0	1
Sterol O-acyltransferase 1	0	1	0	1
DNA polymerase subunit gamma-1	0	0	1	1
Reverse transcriptase/RNaseH	0	1	1	3
Phenylethanolamine N-methyltransferase	0	1	0	1
Amine oxidase [flavin-containing] B	0	3	0	3
Amine oxidase [flavin-containing] A	0	5	0	5
Sodium-dependent noradrenaline transporter	0	11	2	13
Sodium-dependent dopamine transporter	0	3	1	4
Amine oxidase [flavin-containing] B	0	5	0	5
Sodium-dependent serotonin transporter	0	8	3	11
Amine oxidase [flavin-containing] B	0	1	0	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Sigma non-opioid intracellular receptor 1	0	5	1	6
Gamma-aminobutyric acid	0	2	1	3
glp-1 receptor, partial	3	0	0	3
Gamma-aminobutyric acid receptor subunit pi	0	6	0	6
Gamma-aminobutyric acid receptor subunit delta	0	6	0	6
Voltage-dependent L-type calcium channel subunit alpha-1F	0	4	1	5
Fatty acid-binding protein, liver	0	3	0	3
Alpha-1-acid glycoprotein 1	0	0	0	1
Albumin	0	0	1	2
ATP-dependent translocase ABCB1	0	10	0	14
Gamma-aminobutyric acid receptor subunit alpha-1	0	4	0	5
Gamma-aminobutyric acid receptor subunit beta-1	0	4	0	5
Gamma-aminobutyric acid receptor subunit alpha-2	0	4	0	5
Gamma-aminobutyric acid receptor subunit alpha-3	0	4	0	5
Gamma-aminobutyric acid receptor subunit alpha-1	0	7	5	12
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	1	3
Gamma-aminobutyric acid receptor subunit beta-1	0	6	2	8
Gamma-aminobutyric acid receptor subunit gamma-2	0	7	4	11
Gamma-aminobutyric acid receptor subunit alpha-4	0	4	0	5
Gamma-aminobutyric acid receptor subunit gamma-2	0	4	0	5
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	1	3
Gamma-aminobutyric acid receptor subunit delta	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	1	3
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	1	3
Gamma-aminobutyric acid receptor subunit beta-3	0	7	4	11
Translocator protein	0	1	0	1
Translocator protein	0	2	0	2
Cholecystokinin receptor type A	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	6	5	11
Gamma-aminobutyric acid receptor subunit alpha-3	0	6	4	10
Gamma-aminobutyric acid receptor subunit alpha-2	0	6	3	9
Gamma-aminobutyric acid receptor subunit beta-2	0	6	3	9
Gamma-aminobutyric acid receptor subunit alpha-4	0	6	2	8
Gamma-aminobutyric acid receptor subunit beta-1	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	1	3
Gamma-aminobutyric acid receptor subunit beta-3	0	2	1	3
Gamma-aminobutyric acid receptor subunit epsilon	0	6	0	6
Voltage-dependent L-type calcium channel subunit alpha-1D	0	4	1	5
Voltage-dependent L-type calcium channel subunit alpha-1S	0	4	1	5
Voltage-dependent L-type calcium channel subunit alpha-1C	0	6	1	7
Gamma-aminobutyric acid receptor subunit alpha-6	0	6	2	8
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	1	3
Gamma-aminobutyric acid receptor subunit gamma-1	0	6	0	6
Gamma-aminobutyric acid receptor subunit pi	0	2	1	3
Sphingosine-1-phosphate lyase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	6	0	6
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	1	3
Gamma-aminobutyric acid receptor subunit theta	0	2	1	3
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	1	3
Gamma-aminobutyric acid receptor subunit theta	0	6	0	6
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial	0	1	0	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial	0	1	0	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial	0	1	0	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial	0	1	0	1
Chain A, HTH-type transcriptional regulator qacR	0	0	1	1
Chain B, HTH-type transcriptional regulator qacR	0	0	1	1
Chain A, PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY DEOR-FAMILY)	0	0	1	1
Chain B, PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY DEOR-FAMILY)	0	0	1	1
Chain A, Breast cancer type 1 susceptibility protein	2	0	0	2
acid sphingomyelinase	1	0	0	1
RGS12	1	0	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
SMAD family member 2	6	0	0	6
Fumarate hydratase	4	0	0	4
SMAD family member 3	6	0	0	6
DNA polymerase III, partial	1	0	0	1
isocitrate dehydrogenase 1, partial	2	0	0	2
nonstructural protein 1	5	0	0	5
LANA	0	0	0	1
polyprotein	4	0	0	4
serine-protein kinase ATM isoform a	1	0	0	1
lysosomal alpha-glucosidase preproprotein	3	0	0	3
guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1	1	0	0	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	2	0	0	2
serine/threonine-protein kinase PLK1	4	0	0	4
eyes absent homolog 2 isoform a	1	0	0	1
heat shock protein HSP 90-alpha isoform 2	0	1	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	5	0	0	5
caspase-1 isoform alpha precursor	2	0	0	2
DNA dC->dU-editing enzyme APOBEC-3F isoform a	1	0	0	1
kelch-like ECH-associated protein 1	0	0	0	2
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	2	0	2
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta	0	1	0	1
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
3',5'-cyclic-AMP phosphodiesterase	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	3	0	3
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha	0	1	0	1
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	5	0	5
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta	0	1	0	1
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	2	0	2
Caspase-7	2	0	0	2
Disintegrin and metalloproteinase domain-containing protein 17	2	0	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	5	0	5
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	4	0	4
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	5	0	5
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	0	2	0	2
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	2	0	2
Exopolyphosphatase PRUNE1	0	1	0	1
Multidrug and toxin extrusion protein 2	0	2	0	2
Rap guanine nucleotide exchange factor 4	5	0	0	5
Multidrug and toxin extrusion protein 1	0	6	0	6
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 7B	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	3	0	3
Phosphodiesterase	0	1	0	1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	1	0	1
caspase 7, apoptosis-related cysteine protease	5	0	0	5
glucocerebrosidase	3	0	0	3
caspase-3	5	0	0	5
replicative DNA helicase	0	0	0	1
recombinase A	0	0	1	1
UDP-glucuronosyltransferase 1A9	0	1	0	6
UDP-glucuronosyltransferase 2B17	0	0	0	1
UDP-glucuronosyltransferase 1-6	0	1	0	3
UDP-glucuronosyltransferase 1A1	0	1	0	2
UDP-glucuronosyltransferase 1A7	0	0	0	1
Chain A, Protein (peroxisome Proliferator Activated Receptor (ppar-delta))	0	1	0	1
DNA polymerase kappa isoform 1	5	0	0	5
Prostaglandin G/H synthase 1	0	1	0	1
Trypsin	0	1	0	1
Coagulation factor VII	0	2	0	2
Aromatase	0	1	0	1
Tissue factor	0	3	0	3
Retinoic acid receptor RXR-alpha	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	2	3	6
Prostaglandin G/H synthase 2	0	1	0	1
Oxoeicosanoid receptor 1	0	1	0	1
Bone morphogenetic protein receptor type-1B	0	0	2	2
Cell division cycle 7-related protein kinase	0	0	2	2
Serine/threonine-protein kinase PLK4	0	0	2	2
ATP-dependent RNA helicase DDX3X	0	0	2	2
Pyridoxal kinase	0	0	2	2
Citron Rho-interacting kinase	0	0	2	2
Serine/threonine-protein kinase Chk1	0	0	2	2
Aurora kinase A	0	0	2	2
Cyclin-G-associated kinase	0	0	2	2
Ephrin type-B receptor 6	0	0	2	2
Peroxisomal acyl-coenzyme A oxidase 3	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 2	0	0	2	2
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	2	2
Dynamin-like 120 kDa protein, mitochondrial	0	0	2	2
Eukaryotic translation initiation factor 5B	0	0	2	2
Rho-associated protein kinase 2	0	0	2	2
Serine/threonine-protein kinase ULK1	0	0	2	2
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	2	2
Ribosomal protein S6 kinase alpha-5	0	0	2	2
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	2	2
Ribosomal protein S6 kinase alpha-4	0	0	2	2
Serine/threonine-protein kinase 16	0	0	2	2
Serine/threonine-protein kinase 10	0	0	2	2
Serine/threonine-protein kinase D3	0	0	2	2
Structural maintenance of chromosomes protein 2	0	0	2	2
Mitogen-activated protein kinase kinase kinase 6	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	2	2
Serine/threonine-protein kinase LATS1	0	0	2	2
Serine/threonine-protein kinase PAK 4	0	0	2	2
Tyrosine-protein kinase ABL1	0	0	2	2
High affinity nerve growth factor receptor	0	0	2	2
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	1	1
ADP/ATP translocase 2	0	0	2	2
Protein kinase C beta type	0	0	2	2
Tyrosine-protein kinase Lck	0	0	2	2
Tyrosine-protein kinase Fyn	0	0	2	2
Glycogen phosphorylase, liver form	0	0	2	2
Tyrosine-protein kinase Fes/Fps	0	0	2	2
Adenine phosphoribosyltransferase	0	0	2	2
Tyrosine-protein kinase Yes	0	0	2	2
Tyrosine-protein kinase Lyn	0	0	2	2
Proto-oncogene tyrosine-protein kinase receptor Ret	0	0	2	2
Insulin-like growth factor 1 receptor	0	0	2	2
Signal recognition particle receptor subunit alpha	0	0	2	2
Cytochrome c1, heme protein, mitochondrial	0	0	2	2
Hepatocyte growth factor receptor	0	0	2	2
Tyrosine-protein kinase HCK	0	0	2	2
Tyrosine-protein kinase Fgr	0	0	2	2
Serine/threonine-protein kinase A-Raf	0	0	2	2
Glycogen phosphorylase, brain form	0	0	2	2
Breakpoint cluster region protein	0	0	2	2
Serine/threonine-protein kinase pim-1	0	0	2	2
DNA topoisomerase 2-alpha	0	0	2	2
Cyclin-dependent kinase 4	0	0	2	2
ADP/ATP translocase 3	0	0	2	2
Proto-oncogene tyrosine-protein kinase Src	0	0	2	2
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	2	2
Serine/threonine-protein kinase B-raf	0	0	2	2
Potassium voltage-gated channel subfamily E member 1	0	3	0	3
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	2	2
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	0	2	2
Tyrosine-protein kinase Fer	0	0	2	2
cAMP-dependent protein kinase catalytic subunit alpha	0	0	2	2
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	2	2
Casein kinase II subunit alpha'	0	0	2	2
Ras-related protein Rab-6A	0	0	2	2
Ephrin type-A receptor 1	0	0	2	2
Multifunctional protein ADE2	0	0	2	2
cAMP-dependent protein kinase catalytic subunit gamma	0	0	1	1
cAMP-dependent protein kinase catalytic subunit beta	0	0	2	2
Ferrochelatase, mitochondrial	0	0	2	2
Ribosomal protein S6 kinase beta-1	0	0	2	2
Tyrosine-protein kinase JAK1	0	0	2	2
Cyclin-dependent kinase 2	0	0	2	2
Beta-adrenergic receptor kinase 1	0	0	2	2
Probable ATP-dependent RNA helicase DDX6	0	0	2	2
Mitogen-activated protein kinase 3	0	0	2	2
MAP/microtubule affinity-regulating kinase 3	0	0	2	2
Mitogen-activated protein kinase 1	0	1	2	3
Ephrin type-A receptor 2	0	0	2	2
Ephrin type-B receptor 2	0	0	2	2
Non-receptor tyrosine-protein kinase TYK2	0	0	2	2
UMP-CMP kinase	0	0	2	2
Phosphatidylethanolamine-binding protein 1	0	0	2	2
Wee1-like protein kinase	0	0	2	2
Heme oxygenase 2	0	0	2	2
S-adenosylmethionine synthase isoform type-2	0	0	2	2
DnaJ homolog subfamily A member 1	0	0	2	2
RAC-alpha serine/threonine-protein kinase	0	0	2	2
RAC-beta serine/threonine-protein kinase	0	0	2	2
Dual specificity protein kinase TTK	0	0	2	2
DNA replication licensing factor MCM4	0	0	2	2
Myosin-10	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 2	0	0	2	2
Receptor-type tyrosine-protein kinase FLT3	0	0	2	2
Bone morphogenetic protein receptor type-1A	0	0	2	2
Activin receptor type-1B	0	0	2	2
TGF-beta receptor type-1	0	0	2	2
TGF-beta receptor type-2	0	0	2	2
Electron transfer flavoprotein subunit beta	0	0	2	2
Tyrosine-protein kinase CSK	0	0	2	2
Glycine--tRNA ligase	0	0	2	2
Protein kinase C iota type	0	0	2	2
Exosome RNA helicase MTR4	0	0	2	2
Serine/threonine-protein kinase mTOR	0	2	2	4
Tyrosine-protein kinase Tec	0	0	2	2
Tyrosine-protein kinase ABL2	0	0	2	2
Tyrosine-protein kinase FRK	0	0	2	2
G protein-coupled receptor kinase 6	0	0	2	2
Tyrosine-protein kinase SYK	0	0	2	2
26S proteasome regulatory subunit 6B	0	0	2	2
Mitogen-activated protein kinase 8	0	0	2	2
Mitogen-activated protein kinase 9	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 3	0	0	2	2
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	2	2
Casein kinase I isoform alpha	0	0	2	2
Casein kinase I isoform delta	0	0	2	2
MAP kinase-activated protein kinase 2	0	0	2	2
Elongation factor Tu, mitochondrial	0	0	2	2
Choline-phosphate cytidylyltransferase A	0	0	2	2
Cysteine--tRNA ligase, cytoplasmic	0	0	2	2
Casein kinase I isoform epsilon	0	0	2	2
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	2	2
Dual specificity protein kinase CLK1	0	0	2	2
Dual specificity protein kinase CLK2	0	0	2	2
Dual specificity protein kinase CLK3	0	0	2	2
Glycogen synthase kinase-3 alpha	0	0	2	2
Glycogen synthase kinase-3 beta	0	0	2	2
Cyclin-dependent kinase 7	0	0	2	2
Cyclin-dependent kinase 9	0	0	2	2
Ras-related protein Rab-27A	0	0	2	2
Interleukin-1 receptor-associated kinase 1	0	0	2	2
Potassium voltage-gated channel subfamily KQT member 1	0	3	0	3
Ribosomal protein S6 kinase alpha-3	0	0	2	2
Serine/threonine-protein kinase Nek2	0	0	2	2
Serine/threonine-protein kinase Nek3	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 6	0	0	2	2
Serine/threonine-protein kinase PLK1	0	0	2	2
LIM domain kinase 1	0	0	2	2
LIM domain kinase 2	0	0	2	2
Mitogen-activated protein kinase 10	0	0	2	2
Tyrosine--tRNA ligase, cytoplasmic	0	0	2	2
5'-AMP-activated protein kinase subunit gamma-1	0	0	2	2
Ephrin type-B receptor 3	0	0	2	2
Ephrin type-A receptor 5	0	0	2	2
Ephrin type-B receptor 4	0	0	2	2
Ephrin type-A receptor 4	0	0	2	2
Adenylate kinase 2, mitochondrial	0	0	2	2
Ras-related protein Rab-10	0	0	2	2
Actin-related protein 3	0	0	2	2
Actin-related protein 2	0	0	2	2
GTP-binding nuclear protein Ran	0	0	2	2
Casein kinase I isoform gamma-2	0	0	2	2
Cyclin-dependent kinase 3	0	0	1	1
Cyclin-dependent kinase 6	0	0	2	2
Cyclin-dependent-like kinase 5	0	0	2	2
Cyclin-dependent kinase 16	0	0	2	2
Cyclin-dependent kinase 17	0	0	2	2
ATP-dependent 6-phosphofructokinase, platelet type	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 1	0	0	2	2
DNA topoisomerase 2-beta	0	0	2	2
Protein kinase C theta type	0	0	2	2
Activin receptor type-1	0	0	2	2
Macrophage-stimulating protein receptor	0	0	2	2
Focal adhesion kinase 1	0	0	2	2
Protein kinase C delta type	0	0	2	2
Tyrosine-protein kinase BTK	0	0	2	2
Activated CDC42 kinase 1	0	0	2	2
Epithelial discoidin domain-containing receptor 1	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	2	2
Serine/threonine-protein kinase 4	0	0	2	2
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 5	0	0	2	2
Mitogen-activated protein kinase 7	0	0	2	2
Serine/threonine-protein kinase PAK 2	0	0	2	2
Serine/threonine-protein kinase 3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 1	0	0	2	2
Integrin-linked protein kinase	0	0	2	2
Rho-associated protein kinase 1	0	0	2	2
Non-receptor tyrosine-protein kinase TNK1	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	2	2
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	2	2
Activin receptor type-2B	0	0	2	2
Bone morphogenetic protein receptor type-2	0	0	2	2
Protein-tyrosine kinase 6	0	0	2	2
cGMP-dependent protein kinase 1	0	0	2	2
Cyclin-dependent kinase 13	0	0	2	2
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	2	2
Protein-tyrosine kinase 2-beta	0	0	2	2
Sodium channel protein type 5 subunit alpha	0	6	0	6
Maternal embryonic leucine zipper kinase	0	0	2	2
Structural maintenance of chromosomes protein 1A	0	0	2	2
Chromodomain-helicase-DNA-binding protein 4	0	0	2	2
Peroxisomal acyl-coenzyme A oxidase 1	0	0	2	2
Ephrin type-A receptor 7	0	0	1	1
Delta(24)-sterol reductase	0	0	2	2
Ribosomal protein S6 kinase alpha-1	0	0	2	2
Dual specificity testis-specific protein kinase 1	0	0	2	2
Myosin light chain kinase, smooth muscle	0	0	2	2
Mitogen-activated protein kinase 11	0	0	2	2
Serine/threonine-protein kinase STK11	0	0	2	2
Serine/threonine-protein kinase N1	0	0	2	2
Serine/threonine-protein kinase N2	0	0	2	2
Mitogen-activated protein kinase 14	0	1	2	3
Calcium/calmodulin-dependent protein kinase type IV	0	0	2	2
Mitogen-activated protein kinase kinase kinase 11	0	0	2	2
Discoidin domain-containing receptor 2	0	0	2	2
AP2-associated protein kinase 1	0	0	2	2
Myosin light chain kinase 3	0	0	2	2
Putative heat shock protein HSP 90-beta 2	0	0	2	2
Serine/threonine-protein kinase MRCK alpha	0	0	2	2
Serine/threonine-protein kinase MRCK gamma	0	0	2	2
Acyl-CoA dehydrogenase family member 10	0	0	2	2
Serine/threonine-protein kinase N3	0	0	2	2
Serine/threonine-protein kinase ULK3	0	0	2	2
Uncharacterized protein FLJ45252	0	0	2	2
Acyl-CoA dehydrogenase family member 11	0	0	2	2
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	2	2
Serine/threonine-protein kinase MARK2	0	0	2	2
ATP-dependent RNA helicase DHX30	0	0	2	2
Serine/threonine-protein kinase TAO1	0	0	2	2
STE20-related kinase adapter protein alpha	0	0	2	2
Myosin-14	0	0	2	2
AarF domain-containing protein kinase 1	0	0	2	2
ATP-dependent RNA helicase DDX42	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	2	2
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	0	0	1	1
Regulatory-associated protein of mTOR	0	2	0	2
Atypical kinase COQ8A, mitochondrial	0	0	2	2
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	2	2
Mitogen-activated protein kinase 15	0	0	2	2
Serine/threonine-protein kinase Nek9	0	0	2	2
Serine/threonine-protein kinase Nek7	0	0	1	1
ATP-dependent RNA helicase DDX1	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	2	2
Aurora kinase B	0	0	2	2
MAP/microtubule affinity-regulating kinase 4	0	0	2	2
Serine/threonine-protein kinase Nek1	0	0	2	2
PAS domain-containing serine/threonine-protein kinase	0	0	2	2
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	2	2
EKC/KEOPS complex subunit TP53RK	0	0	2	2
Dual specificity testis-specific protein kinase 2	0	0	2	2
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	2	2
Mitogen-activated protein kinase kinase kinase 5	0	0	2	2
Mitogen-activated protein kinase kinase kinase 3	0	0	2	2
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	2	2
Target of rapamycin complex subunit LST8	0	2	0	2
Nucleolar GTP-binding protein 1	0	0	2	2
Serine/threonine-protein kinase D2	0	0	2	2
NUAK family SNF1-like kinase 2	0	0	1	1
RNA cytidine acetyltransferase	0	0	2	2
Serine/threonine-protein kinase SIK2	0	0	2	2
STE20-like serine/threonine-protein kinase	0	0	2	2
Serine/threonine-protein kinase TAO3	0	0	2	2
dCTP pyrophosphatase 1	0	0	2	2
Dual specificity protein kinase CLK4	0	0	2	2
Casein kinase I isoform gamma-1	0	0	2	2
Phenylalanine--tRNA ligase beta subunit	0	0	2	2
BMP-2-inducible protein kinase	0	0	2	2
Obg-like ATPase 1	0	0	2	2
Midasin	0	0	2	2
Interleukin-1 receptor-associated kinase 4	0	0	2	2
Mitogen-activated protein kinase kinase kinase 20	0	0	2	2
Cyclin-dependent kinase 12	0	0	2	2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	1	1
Serine/threonine-protein kinase 26	0	0	2	2
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	2	2
Serine/threonine-protein kinase NLK	0	0	2	2
5'-AMP-activated protein kinase subunit gamma-2	0	0	2	2
Serine/threonine-protein kinase TBK1	0	0	2	2
Septin-9	0	0	2	2
Potassium voltage-gated channel subfamily D member 3	0	1	0	1
Ribosomal protein S6 kinase alpha-6	0	0	2	2
TRAF2 and NCK-interacting protein kinase	0	0	2	2
Serine/threonine-protein kinase TAO2	0	0	2	2
Long-chain-fatty-acid--CoA ligase 5	0	0	1	1
RAC-gamma serine/threonine-protein kinase	0	0	2	2
Serine/threonine-protein kinase SIK3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 2	0	0	2	2
Thyroid hormone receptor-associated protein 3	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 3	0	0	2	2
Serine/threonine-protein kinase MRCK beta	0	0	2	2
Interleukin-1 receptor-associated kinase 3	0	0	2	2
Casein kinase I isoform gamma-3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 4	0	0	2	2
Nuclear receptor subfamily 1 group I member 2	0	0	3	3
Kappa-type opioid receptor	0	2	0	2
Histamine H1 receptor	0	5	1	6
Mu-type opioid receptor	0	1	0	1
endonuclease IV	2	0	0	2
Caspase-7	3	0	0	3
NPC intracellular cholesterol transporter 1 precursor	2	0	0	2
caspase-3	3	0	0	3
huntingtin isoform 2	2	0	0	2
Sodium-dependent noradrenaline transporter	0	1	0	1
5-hydroxytryptamine receptor 4	0	9	0	9
Potassium channel subfamily K member 2	0	3	1	4
Aldo-keto reductase family 1 member B1	0	9	0	9
Muscarinic acetylcholine receptor M5	0	6	0	6
Alpha-2A adrenergic receptor	0	5	0	5
Muscarinic acetylcholine receptor M1	0	5	1	6
Angiotensin-converting enzyme	0	4	0	4
Dipeptidyl peptidase 4	0	1	0	1
Muscarinic acetylcholine receptor M3	0	5	0	5
Acetylcholinesterase	0	2	0	2
Prostaglandin G/H synthase 1	0	3	0	3
Potassium voltage-gated channel subfamily C member 1	0	1	0	1
5-hydroxytryptamine receptor 2C	0	9	0	9
5-hydroxytryptamine receptor 6	0	7	0	7
Gastrin/cholecystokinin type B receptor	0	1	0	1
Sodium-dependent serotonin transporter	0	1	0	1
Sodium-dependent dopamine transporter	0	1	0	1
Transporter	0	3	0	3
Nuclear receptor subfamily 3 group C member 3	0	3	0	3
Beta-2 adrenergic receptor	0	1	0	1
Transporter	0	2	0	2
Histamine H3 receptor	0	1	0	1
Beta-galactosidase	0	1	0	1
Lipopolysaccharide heptosyltransferase 1	0	1	0	1
PA-I galactophilic lectin	0	0	1	1
Jacalin	0	0	1	1
Gamma-aminobutyric acid receptor subunit rho-3	0	0	1	1
Hsf1 protein	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 2	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	2	0	2
Gamma-aminobutyric acid receptor subunit rho-1	0	0	2	2
Gamma-aminobutyric acid receptor subunit rho-2	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	2	0	2
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
Sterol O-acyltransferase 1	0	0	1	1
Platelet glycoprotein VI	0	1	2	4
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Gamma-aminobutyric acid type B receptor subunit 1	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 1	0	1	0	1
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
beta-2 adrenergic receptor	1	0	0	1
Metabotropic glutamate receptor 8	0	2	0	2
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Glutathione reductase, mitochondrial	0	2	0	2
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
Prothrombin	0	0	1	1
ATP-citrate synthase	0	1	0	1
Glutamate receptor 1	0	2	1	3
Glutamate receptor 3	0	2	1	3
Glutamate receptor 4	0	2	1	3
Glutamate receptor ionotropic, kainate 1	0	2	1	3
Metabotropic glutamate receptor 1	0	1	1	2
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 5	0	0	1	1
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Glutamate receptor ionotropic, kainate 1	0	1	1	2
Metabotropic glutamate receptor 5	0	1	1	3
Glutamate receptor ionotropic, kainate 2	0	2	1	3
Glutamate receptor 1	0	2	1	3
Glutamate receptor 2	0	2	1	3
Glutamate receptor 3	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	2	0	2
Metabotropic glutamate receptor 8	0	0	1	1
Glutamate receptor 4	0	2	1	3
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Glutamate receptor ionotropic, kainate 4	0	2	0	2
Glutamate carboxypeptidase 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	1	0	1
Glutamate receptor ionotropic, kainate 2	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	1	0	1
Metabotropic glutamate receptor 7	0	1	1	3
Metabotropic glutamate receptor 3	0	1	1	3
Metabotropic glutamate receptor 4	0	1	1	3
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Glutamate receptor ionotropic, kainate 5	0	1	0	1
Glutamate receptor ionotropic, kainate 5	0	2	0	2
Glutamate racemase	0	0	0	1
Prolyl 4-hydroxylase	0	3	0	3
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Alpha-ketoglutarate-dependent dioxygenase FTO	0	2	0	2
Chain A, Glutamine Binding Protein	0	0	1	1
Neutral amino acid transporter A	0	1	0	1
Asc-type amino acid transporter 1	0	1	0	1
Neutral amino acid transporter B(0)	0	1	0	1
Amino acid transporter	0	1	0	1
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E	0	0	1	1
Glycine receptor subunit alpha-1	0	0	1	1
Sodium- and chloride-dependent glycine transporter 1	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	6	0	7
Serine racemase	0	1	0	1
Olfactory receptor 51E2	0	1	1	2
Sodium- and chloride-dependent glycine transporter 2	0	1	0	1
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	1
Ricin	0	1	0	1
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	0	0	1	1
Purine nucleoside phosphorylase	0	0	1	2
Shiga toxin subunit A	0	1	0	1
Guanine deaminase	0	1	0	2
Adenylate cyclase type 1	0	1	0	1
transient receptor potential cation channel subfamily V member 1	1	0	0	1
Transient receptor potential cation channel subfamily V member 1	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Vitamin D-binding protein	0	1	0	1
HLA class I histocompatibility antigen, A alpha chain	0	0	1	1
Integrin beta-1	0	1	0	1
Muscarinic acetylcholine receptor M2	0	2	0	2
Muscarinic acetylcholine receptor M4	0	3	0	3
Muscarinic acetylcholine receptor M1	0	2	1	3
Muscarinic acetylcholine receptor M3	0	2	1	3
Muscarinic acetylcholine receptor M4	0	2	1	3
Muscarinic acetylcholine receptor M5	0	2	1	3
Beta-2 adrenergic receptor	0	2	0	2
Muscarinic acetylcholine receptor M2	0	2	1	3
Integrin alpha-4	0	1	0	1
Carbonyl reductase [NADPH] 1	0	0	0	1
Beta-1 adrenergic receptor	0	1	0	1
Alpha-2C adrenergic receptor	0	4	0	4
Adenylate cyclase type 3	0	1	0	1
UDP-glucuronosyltransferase 1A4	0	1	0	3
5-hydroxytryptamine receptor 3A	0	1	0	1
Histamine H2 receptor	0	2	0	2
Alpha-1D adrenergic receptor	0	4	0	4
Beta-3 adrenergic receptor	0	1	0	1
Adenylate cyclase type 2	0	1	0	1
Adenylate cyclase type 4	0	1	0	1
Histamine H1 receptor	0	2	0	2
C-8 sterol isomerase	0	1	0	1
5-hydroxytryptamine receptor 2C	0	1	0	1
5-hydroxytryptamine receptor 7	0	3	0	3
Alpha-1A adrenergic receptor	0	3	0	3
5-hydroxytryptamine receptor 2A	0	1	0	1
Alpha-1B adrenergic receptor	0	2	0	2
Sodium channel protein type 1 subunit alpha	0	2	0	2
Adenylate cyclase type 8	0	1	0	1
5-hydroxytryptamine receptor 2B	0	8	0	8
5-hydroxytryptamine receptor 2A	0	1	0	1
D(2) dopamine receptor	0	1	0	1
D(3) dopamine receptor	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
AP-2 complex subunit sigma	0	1	0	1
N-acetyltransferase Eis	0	2	0	2
Sodium channel protein type 7 subunit alpha	0	1	0	1
5-hydroxytryptamine receptor 2B	0	1	0	1
Adenylate cyclase type 6	0	1	0	1
Adenylate cyclase type 5	0	1	0	1
5-hydroxytryptamine receptor 4	0	2	1	3
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	1	0	1
Calcitonin gene-related peptide type 1 receptor	0	1	0	1
Genome polyprotein	0	2	0	2
Sigma intracellular receptor 2	0	1	0	1
Zinc finger protein 664	0	1	0	1
Vesicular acetylcholine transporter	0	1	0	1
Cholecystokinin receptor type A	0	1	0	1
Protease	0	2	0	2
Adenylyl cyclase 7	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	3	0	3
Transient receptor potential cation channel subfamily V member 4	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	4	0	4
Sodium channel protein type 11 subunit alpha	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	1	0	1
Transient receptor potential cation channel subfamily V member 2	0	1	0	1
Sodium channel protein type 10 subunit alpha	0	2	0	2
Chain A, HISTIDINE-BINDING PROTEIN	0	0	1	1
Plasma kallikrein	0	0	0	3
Histidine-binding periplasmic protein	0	0	1	1
Glutaminyl-peptide cyclotransferase	0	1	0	1
Phosphatidylcholine-sterol acyltransferase	0	0	1	1
G-protein coupled receptor 1	0	0	1	1
NAD-dependent protein deacetylase sirtuin-2	0	2	0	2
NAD-dependent protein deacetylase	0	2	0	2
Chain B, Pulmonary surfactant-associated protein D	0	1	0	1
Chain A, Pulmonary surfactant-associated protein D	0	1	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	3	0	0	3
Sodium/myo-inositol cotransporter 2	0	1	0	1
atrial natriuretic peptide receptor 1 precursor	3	0	0	3
Chain A, Cruzipain	5	0	0	5
Ornithine decarboxylase	0	0	0	1
Retinoic acid receptor alpha	0	1	0	1
Retinoic acid receptor gamma	0	1	0	1
Retinoic acid receptor beta	0	1	0	1
Cellular retinoic acid-binding protein 2	0	0	1	1
Retinoic acid receptor RXR-alpha	0	1	0	1
Retinoic acid receptor RXR-beta	0	1	0	1
Retinoic acid receptor RXR-gamma	0	1	0	1
Cellular retinoic acid-binding protein 1	0	1	0	1
Cellular retinoic acid-binding protein 1	0	0	1	1
Chymotrypsinogen A	0	1	0	1
Sodium channel protein type 10 subunit alpha	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Chain A, AMINOPEPTIDASE	0	2	0	2
Chain A, AMINOPEPTIDASE	0	2	0	2
Chain A, Leucine Aminopeptidase	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	4	0	4
Intestinal-type alkaline phosphatase	0	3	0	3
Phospholipase A-2-activating protein	0	3	0	3
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
Synaptic vesicle glycoprotein 2A	0	1	0	1
Potassium channel subfamily K member 3	0	2	0	2
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
Estrogen receptor	0	0	1	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	1
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial	0	1	0	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	1	0	1
Estrogen receptor beta	0	0	1	1
Renin	0	1	0	1
Neprilysin	0	1	0	1
Angiotensin-converting enzyme	0	1	0	1
Atrial natriuretic peptide receptor 3	0	1	0	1
Thromboxane A2 receptor	0	1	0	2
Type-1A angiotensin II receptor	0	2	1	3
Type-1B angiotensin II receptor	0	2	0	2
Type-1 angiotensin II receptor	0	2	1	5
Type-1 angiotensin II receptor	0	1	1	2
Type-2 angiotensin II receptor	0	2	0	2
Type-2 angiotensin II receptor	0	1	0	1
Solute carrier organic anion transporter family member 1B3	0	2	0	2
Type-1 angiotensin II receptor	0	1	1	2
Solute carrier organic anion transporter family member 1B1	0	5	0	5
Chain A, Antigen Cd11a (p180)	0	1	0	1
PINK1	2	0	0	2
nuclear receptor subfamily 1, group I, member 2	4	0	0	4
urokinase-type plasminogen activator precursor	2	0	0	2
plasminogen precursor	2	0	0	2
bcl-2-related protein A1	0	1	0	1
urokinase plasminogen activator surface receptor precursor	2	0	0	2
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	3	0	3
Integrin beta-2	0	1	0	1
Intercellular adhesion molecule 1	0	1	0	1
Neutrophil elastase	0	1	0	1
Insulin receptor	0	2	0	2
Integrin alpha-L	0	1	1	2
Substance-K receptor	0	2	0	2
Prostaglandin G/H synthase 2	0	3	0	3
Nuclear receptor ROR-gamma	3	0	0	3
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	3	0	3
Lanosterol 14-alpha demethylase	0	1	0	1
Acyl-CoA:cholesterol acyltransferase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Glucocorticoid receptor	0	4	1	10
Glycine receptor subunit alpha-1	0	4	0	4
Glycine receptor subunit beta	0	4	0	4
Glycine receptor subunit alpha-2	0	4	0	4
Glycine receptor subunit alpha-3	0	4	0	4
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
ATP-dependent translocase ABCB1	0	1	0	1
ATP-dependent translocase ABCB1	0	1	0	1
UDP-glucuronosyltransferase 2B10	0	1	0	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	0	0	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	0	0	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
Chain A, NAD-dependent deacetylase	0	1	0	1
Poly [ADP-ribose] polymerase 2	0	1	0	1
NAD-dependent histone deacetylase SIR2	0	1	0	1
Poly [ADP-ribose] polymerase 1	0	1	0	1
Cytochrome P450 3A5	0	1	0	1
NAD-dependent protein deacetylase HST2	0	1	0	1
NAD(+) hydrolase SARM1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-6	0	1	0	1
NAD-dependent protein deacetylase sirtuin-1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	1	0	1
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	2	0	2
5-hydroxytryptamine receptor 3E	0	2	0	2
FAD-linked sulfhydryl oxidase ALR	0	0	0	1
5-hydroxytryptamine receptor 3B	0	2	0	2
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Histamine H1 receptor	0	1	1	2
5-hydroxytryptamine receptor 3A	0	3	0	3
5-hydroxytryptamine receptor 3D	0	2	0	2
5-hydroxytryptamine receptor 3C	0	2	0	2
Chain A, ARGINASE 1	0	1	0	1
Chain A, Arginase 1	0	1	0	1
Chain A, ARGINASE 1	0	1	0	1
Chain A, L-ARGININE\\:GLYCINE AMIDINOTRANSFERASE	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
E3 ubiquitin-protein ligase XIAP	0	1	0	1
SLC16A10 protein	0	0	0	2
Large neutral amino acids transporter small subunit 1	0	1	0	1
Monocarboxylate transporter 10	0	0	0	2
Dihydrofolate reductase	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
CDGSH iron-sulfur domain-containing protein 1	0	1	0	1
tyrosine-protein kinase Yes	1	0	0	1
Free fatty acid receptor 1	0	0	1	1
Peroxisome proliferator-activated receptor gamma	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	1
Carnitine O-palmitoyltransferase 2, mitochondrial	0	1	0	1
Peroxisome proliferator-activated receptor alpha	0	1	0	1
Carnitine O-palmitoyltransferase 2, mitochondrial	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	1	1	2
Carnitine O-palmitoyltransferase 1, liver isoform	0	1	0	1
Peroxisome proliferator-activated receptor alpha	0	1	1	2
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
CDGSH iron-sulfur domain-containing protein 2	0	1	0	1
CDGSH iron-sulfur domain-containing protein 1	0	2	0	2
luciferase	0	0	0	1
Estrogen receptor	0	2	0	2
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Corticosteroid-binding globulin	0	1	0	1
Mineralocorticoid receptor	0	2	1	3
Androgen receptor	0	2	0	2
Glutamine synthetase	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Fatty-acid amide hydrolase 1	0	1	0	1
UDP-glucuronosyltransferase 1A8	0	0	0	1
Monocarboxylate transporter 2	0	0	0	1
Monocarboxylate transporter 1	0	0	0	1
C-terminal-binding protein 2	0	1	0	1
Solute carrier organic anion transporter family member 2A1	0	1	0	1
Chain A, 6,7-Dimethyl-8-ribityllumazine Synthase	0	0	1	1
Chain B, 6,7-Dimethyl-8-ribityllumazine Synthase	0	0	1	1
Chain H, Immunoglobulin Igg1 Heavy chain	0	0	1	1
Chain L, Immunoglobulin Igg1 Lambda Light Chain	0	0	1	1
Chain A, DODECIN	0	0	1	1
Chain A, DODECIN	0	0	1	1
Chain C, DODECIN	0	0	1	1
Chain E, DODECIN	0	0	1	1
tumor necrosis factor	1	0	0	1
nuclear factor NF-kappa-B p105 subunit isoform 1	1	0	0	1
Riboflavin-binding protein	0	1	1	2
DNA polymerase beta	1	0	0	1
Pancreatic triacylglycerol lipase	0	1	0	1
NADH-ubiquinone oxidoreductase chain 1	0	1	0	1
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial	0	1	0	1
Dihydroorotate dehydrogenase (fumarate)	0	1	0	1
Acyl carrier protein, mitochondrial	0	1	0	1
Dihydroorotate dehydrogenase	0	1	0	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, 146aa long hypothetical transcriptional regulator	0	0	1	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain B, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain C, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Anthranilate phosphoribosyltransferase	0	1	0	1
photoreceptor-specific nuclear receptor	0	1	0	1
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	0	0	1
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Tyrosine-protein kinase JAK2	0	0	1	1
Cyclin-dependent kinase-like 5	0	0	1	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
Eukaryotic translation initiation factor 4E	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	1	0	1
Serine/threonine-protein kinase receptor R3	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	1	3
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Protein kinase C zeta type	0	0	1	1
Cyclin-dependent kinase 18	0	0	1	1
Tyrosine-protein kinase Mer	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Uncharacterized aarF domain-containing protein kinase 5	0	0	1	1
Programmed cell death protein 4	0	0	1	1
MAP kinase-activated protein kinase 5	0	0	1	1
Misshapen-like kinase 1	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1G	0	0	1	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Isoleucine--tRNA ligase, mitochondrial	0	0	1	1
Serine/threonine-protein kinase ICK	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	1	1
Serine/threonine-protein kinase 24	0	0	1	1
Chain A, Protein (aspartate Aminotransferase)	0	0	1	1
Chain A, Aspartate Aminotransferase	0	0	1	1
NADP-dependent malic enzyme, mitochondrial	0	0	0	1
Solute carrier family 13 member 3	0	1	0	1
Methyl-accepting chemotaxis protein NahY	0	0	1	1
Carboxypeptidase M	0	1	0	1
5-hydroxytryptamine receptor 1B	0	2	1	3
5-hydroxytryptamine receptor 1E	0	1	0	1
5-hydroxytryptamine receptor 1F	0	2	1	3
5-hydroxytryptamine receptor 5A	0	1	0	1
5-hydroxytryptamine receptor 1B	0	1	0	1
5-hydroxytryptamine receptor 1D	0	1	0	1
5-hydroxytryptamine receptor 1A	0	1	0	1
5-hydroxytryptamine receptor 1B	0	1	0	1
Chain A, Multidrug-efflux Transporter 1 Regulator Bmrr	0	0	1	1
Chain A, Pyridoxal kinase	0	1	0	1
Chain A, Pyridoxal Kinase	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Thyroid hormone receptor beta	0	1	0	1
Adenosine receptor A1	0	2	0	2
Vasopressin V2 receptor	0	0	0	1
Adenosine receptor A2a	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	1	0	1
Adenosine receptor A1	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Adenylate cyclase type 1	0	0	0	1
Chitotriosidase-1	0	1	0	1
Adenosine receptor A2b	0	0	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	0	1	1
Endochitinase B1	0	1	0	1
Chain A, ykoF	0	0	1	1
Chain B, ykoF	0	0	1	1
Chain A, ThiT	0	0	1	1
Thiamine transporter ThiT	0	0	1	1
Transketolase	0	0	1	1
Thiamine-binding periplasmic protein	0	0	1	1
Acetylcholinesterase	0	1	0	1
1-deoxy-D-xylulose-5-phosphate synthase	0	0	1	1
1-deoxy-D-xylulose-5-phosphate synthase	0	0	1	1
Cytochrome P450 2B1	0	1	0	1
Thymidine phosphorylase	0	1	0	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Taste receptor type 2 member 14	0	0	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Solute carrier family 22 member 6	0	0	0	1
Solute carrier family 22 member 8	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
Chain A, Cytidine Deaminase	0	1	0	1
Cytidine deaminase	0	1	0	1
Protein cereblon	0	2	0	2
Uridine-cytidine kinase 1	0	0	0	1
Chain A, Arginase 1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member B7	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research Excerpts

Overview

Treatment

Research

Studies (332)

Protein Targets (1,588)

MELAS Syndrome

Synonyms(1)

Research Excerpts

Overview

Treatment

Research

Studies (332)

Drugs Studied (188)

Protein Targets (1,588)