Lipodystrophy, Familial Partial

Inherited conditions characterized by the partial loss of ADIPOSE TISSUE, either confined to the extremities with normal or increased fat deposits on the face, neck and trunk (type 1), or confined to the loss of SUBCUTANEOUS FAT from the limbs and trunk (type 2). Type 3 is associated with mutation in the gene encoding PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA.

Synonym
Lipodystrophy, Familial Partial

Excerpt	Reference
"Familial partial lipodystrophy are Mendelian disorders involving abnormal body fat distribution and insulin resistance."	( Araújo-Vilar, D; Casanueva, FF; Castro-Pais, A; Fernández-Marmiesse, A; González-Méndez, B; Guillín-Amarelle, C; Ordóñez-Mayán, L; Pazos, M; Rodriguez-Cañete, L; Rodríguez-García, S; Sánchez-Iglesias, S, 2016)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	0 (0.00)	23.3326
1990's	0 (0.00)	12.5806
2000's	19 (34.55)	18.1394
2010's	30 (54.55)	28.8240
2020's	6 (10.91)	9.53

Drug	Relationship Strength	Studies	Trials
carnitine	low	1	0
palmitic acid	low	1	0
clofibric acid	low	1	0
metformin	low	5	0
pioglitazone	low	9	0
troglitazone	low	1	0
spironolactone	low	1	0
glutamine	low	1	0
leucine	low	1	0
histidine	low	1	0
tryptophan	low	1	0
arginine	low	3	0
cdaa	low	1	0
s-adenosylmethionine	low	1	0
nelfinavir	low	1	0
rosiglitazone	low	4	0
lopinavir	low	1	0
angiotensin ii	low	1	0
glycogen	low	1	0
isomethyleugenol	low	1	0
gw9662	low	1	0
indinavir sulfate	low	1	0
cysteine	low	1	0
emerin	low	4	0
oligonucleotides	low	2	0
liraglutide	low	1	0
transforming growth factor beta	low	2	0
leptin	medium	15	2

Protein Targets (466)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
glucocerebrosidase	2	0	0	2
DNA polymerase kappa isoform 1	3	0	0	3
histone acetyltransferase KAT2A isoform 1	5	0	0	5
Atrial natriuretic peptide receptor 3	0	1	0	1
Type-1A angiotensin II receptor	0	2	1	3
Type-1 angiotensin II receptor	0	0	1	1
Type-1B angiotensin II receptor	0	2	0	2
Type-1 angiotensin II receptor	0	2	2	4
Type-2 angiotensin II receptor	0	2	0	2
Type-2 angiotensin II receptor	0	2	0	2
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	4	0	0	4
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
thioredoxin reductase	4	0	0	4
phosphopantetheinyl transferase	3	0	0	3
NFKB1 protein, partial	2	0	0	2
GLS protein	4	0	0	4
thyroid stimulating hormone receptor	3	0	0	3
alpha-galactosidase	2	0	0	2
euchromatic histone-lysine N-methyltransferase 2	6	0	0	6
cytochrome P450 2C19 precursor	3	0	0	3
chromobox protein homolog 1	2	0	0	2
flap endonuclease 1	5	0	0	5
DNA polymerase iota isoform a (long)	2	0	0	2
muscarinic acetylcholine receptor M1	2	0	0	2
lethal factor (plasmid)	1	0	0	1
Cytochrome P450 3A4	0	6	1	9
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, inducible	0	0	0	1
Nitric oxide synthase, inducible	0	0	1	3
Cationic amino acid transporter 3	0	1	0	1
ATP-dependent phosphofructokinase	3	0	0	3
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 5	0	0	0	1
Bile salt export pump	0	9	0	9
Solute carrier family 22 member 16	0	0	0	1
Solute carrier family 22 member 21	0	0	0	1
Solute carrier family 22 member 5	0	0	0	1
Chain A, Beta-lactamase	1	0	0	1
USP1 protein, partial	6	0	0	6
TDP1 protein	9	0	0	9
Microtubule-associated protein tau	4	0	0	4
glucocorticoid receptor [Homo sapiens]	9	0	0	9
peroxisome proliferator-activated receptor delta	6	0	0	6
cytochrome P450 2D6 isoform 1	2	0	0	2
thyroid hormone receptor beta isoform a	3	0	0	3
cytochrome P450 3A4 isoform 1	4	0	0	4
Gamma-aminobutyric acid receptor subunit pi	4	0	0	4
Glutamate receptor ionotropic, NMDA 2D	0	0	2	2
Glutamate receptor ionotropic, NMDA 3B	0	0	2	2
Fatty acid-binding protein, intestinal	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	4	0	0	4
Gamma-aminobutyric acid receptor subunit delta	4	0	0	4
Gamma-aminobutyric acid receptor subunit gamma-2	4	0	0	4
Gamma-aminobutyric acid receptor subunit alpha-5	4	0	0	4
Gamma-aminobutyric acid receptor subunit alpha-3	4	0	0	4
Peroxisome proliferator-activated receptor alpha	0	2	2	4
Gamma-aminobutyric acid receptor subunit gamma-1	4	0	0	4
Gamma-aminobutyric acid receptor subunit alpha-2	4	0	0	4
Gamma-aminobutyric acid receptor subunit alpha-4	4	0	0	4
Gamma-aminobutyric acid receptor subunit gamma-3	4	0	0	4
Gamma-aminobutyric acid receptor subunit alpha-6	4	0	0	4
Peroxisome proliferator-activated receptor gamma	0	7	7	17
Peroxisome proliferator-activated receptor gamma	0	1	4	5
Gamma-aminobutyric acid receptor subunit alpha-1	4	0	0	4
Gamma-aminobutyric acid receptor subunit beta-3	4	0	0	4
Gamma-aminobutyric acid receptor subunit beta-2	4	0	0	4
Peroxisome proliferator-activated receptor delta	0	2	2	4
Glutamate receptor ionotropic, NMDA 1	0	0	2	2
Neuronal acetylcholine receptor subunit alpha-7	0	0	1	1
Peroxisome proliferator-activated receptor alpha	1	3	4	9
Glutamate receptor ionotropic, NMDA 2A	0	0	2	2
Glutamate receptor ionotropic, NMDA 2B	0	0	2	2
Glutamate receptor ionotropic, NMDA 2C	0	0	2	2
Glutamate receptor ionotropic, NMDA 3A	0	0	2	2
GABA theta subunit	4	0	0	4
Gamma-aminobutyric acid receptor subunit epsilon	4	0	0	4
Chain A, Glutamine Binding Protein	0	0	1	1
15-lipoxygenase, partial	1	0	0	1
arylsulfatase A	3	0	0	3
Bloom syndrome protein isoform 1	2	0	0	2
peripheral myelin protein 22 isoform 1	3	0	0	3
histone-lysine N-methyltransferase 2A isoform 2 precursor	2	0	0	2
Carbonic anhydrase 1	0	0	0	4
Carbonic anhydrase 2	0	3	0	7
Neutral amino acid transporter A	0	1	0	1
Asc-type amino acid transporter 1	0	1	0	1
Neutral amino acid transporter B(0)	0	1	0	1
Carbonic anhydrase-like protein, putative	0	0	0	3
Amino acid transporter	0	1	0	1
Chain A, Ferritin light chain	4	0	0	4
Luciferase	3	0	0	3
Nrf2	1	0	0	1
SMAD family member 2	4	0	0	4
ATAD5 protein, partial	2	0	0	2
SMAD family member 3	4	0	0	4
GLI family zinc finger 3	6	0	0	6
Thrombopoietin	1	0	0	1
AR protein	7	0	0	7
estrogen receptor 2 (ER beta)	4	0	0	4
nuclear receptor subfamily 1, group I, member 3	4	0	0	4
retinoic acid nuclear receptor alpha variant 1	6	0	0	6
retinoid X nuclear receptor alpha	4	0	0	4
estrogen-related nuclear receptor alpha	7	0	0	7
pregnane X nuclear receptor	4	0	0	4
estrogen nuclear receptor alpha	8	0	0	8
bromodomain adjacent to zinc finger domain 2B	3	0	0	3
peroxisome proliferator activated receptor gamma	7	0	0	7
vitamin D (1,25- dihydroxyvitamin D3) receptor	3	0	0	3
pyruvate kinase	1	0	0	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	1	0	0	1
aryl hydrocarbon receptor	2	0	0	2
neutrophil cytosol factor 1	0	1	0	1
cellular tumor antigen p53 isoform a	1	0	0	1
cytochrome P450 2C9 precursor	1	0	0	1
thyroid hormone receptor beta isoform 2	7	0	0	7
heat shock protein beta-1	2	0	0	2
mitogen-activated protein kinase 1	1	0	0	1
serine/threonine-protein kinase mTOR isoform 1	1	0	0	1
eyes absent homolog 2 isoform a	1	0	0	1
nuclear factor erythroid 2-related factor 2 isoform 1	5	0	0	5
geminin	8	0	0	8
survival motor neuron protein isoform d	1	0	0	1
M-phase phosphoprotein 8	2	0	0	2
muscleblind-like protein 1 isoform 1	1	0	0	1
lamin isoform A-delta10	4	0	0	4
pyruvate kinase PKM isoform b	1	0	0	1
Voltage-dependent calcium channel gamma-2 subunit	4	0	0	4
Cellular tumor antigen p53	7	0	0	7
Integrin beta-3	1	0	0	1
Integrin alpha-IIb	1	0	0	1
Ornithine decarboxylase	1	0	0	1
Glutamate receptor 2	4	0	0	4
Histamine H2 receptor	2	0	0	2
Nuclear receptor ROR-gamma	0	1	0	1
Chain A, HISTIDINE-BINDING PROTEIN	0	0	1	1
Carbonic anhydrase 12	0	0	0	2
Plasma kallikrein	0	0	0	2
Carbonic anhydrase 3	0	0	0	2
Histidine-binding periplasmic protein	0	0	1	1
Carbonic anhydrase 4	0	0	0	2
Carbonic anhydrase 6	0	0	0	2
Adenosine receptor A1	0	0	0	1
5-hydroxytryptamine receptor 1D	0	0	0	1
Adenosine receptor A2a	0	0	0	1
Carbonic anhydrase 5A, mitochondrial	0	0	0	2
Glutamate receptor ionotropic, NMDA 1	0	0	1	3
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase 7	0	0	0	2
Carbonic anhydrase	0	0	0	2
Glutamate receptor ionotropic, NMDA 2A	0	0	0	2
Glutamate receptor ionotropic, NMDA 2B	0	0	0	2
Glutamate receptor ionotropic, NMDA 2C	0	0	0	2
Large neutral amino acids transporter small subunit 1	0	3	0	3
Glutaminyl-peptide cyclotransferase	0	1	0	1
Carbonic anhydrase 9	0	0	0	2
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	0	0	2
Glutamate receptor ionotropic, NMDA 2D	0	0	0	2
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase 13	0	0	0	1
Glutamate receptor ionotropic, NMDA 3B	0	0	0	2
Carbonic anhydrase 4	0	0	0	1
Carbonic anhydrase 15	0	0	0	2
Carbonic anhydrase 13	0	0	0	2
Glutamate receptor ionotropic, NMDA 3A	0	0	0	2
Carbonic anhydrase 14	0	0	0	2
Carbonic anhydrase 5B, mitochondrial	0	0	0	2
Chain A, PROTEIN (PROTEASE)	0	1	0	1
Chain B, PROTEIN (PROTEASE)	0	1	0	1
Chain A, PROTEIN (PROTEASE)	0	1	0	1
Chain B, PROTEIN (PROTEASE)	0	1	0	1
Chain A, HIV-1 PROTEASE	0	1	0	1
Chain B, HIV-1 PROTEASE	0	1	0	1
Chain A, HIV-II PROTEASE	0	1	0	1
Chain B, HIV-II PROTEASE	0	1	0	1
Chain A, POL polyprotein	0	0	1	1
Chain B, POL polyprotein	0	0	1	1
Chain A, POL polyprotein	0	0	1	1
Chain B, POL polyprotein	0	0	1	1
Chain A, POL polyprotein	0	0	1	1
Chain B, POL polyprotein	0	0	1	1
Chain A, POL polyprotein	0	0	1	1
Chain B, POL polyprotein	0	0	1	1
Chain A, protease RETROPEPSIN	0	1	0	1
Chain B, protease RETROPEPSIN	0	1	0	1
Chain A, protease RETROPEPSIN	0	1	0	1
Chain B, protease RETROPEPSIN	0	1	0	1
Chain A, protease RETROPEPSIN	0	1	0	1
Chain B, protease RETROPEPSIN	0	1	0	1
Chain A, POL polyprotein	0	1	0	1
Chain B, POL polyprotein	0	1	0	1
Chain A, POL polyprotein	0	1	0	1
Chain B, POL polyprotein	0	1	0	1
Chain A, HIV-1 protease	0	1	0	1
Chain B, HIV-1 protease	0	1	0	1
Chain A, Pol polyprotein	0	1	0	1
Chain B, Pol polyprotein	0	1	0	1
Chain A, Pol polyprotein	0	1	0	1
Chain B, Pol polyprotein	0	1	0	1
Chain A, Pol polyprotein	0	1	0	1
Chain B, Pol polyprotein	0	1	0	1
Chain A, Pol polyprotein	0	1	0	1
Chain B, Pol polyprotein	0	1	0	1
Chain A, Hiv-1 Protease	0	1	0	1
Chain B, Hiv-1 Protease	0	1	0	1
Chain A, Hiv-1 Protease	0	1	0	1
Chain B, Hiv-1 Protease	0	1	0	1
Chain A, Hiv-1 Protease	0	1	0	1
Chain B, Hiv-1 Protease	0	1	0	1
cytochrome P450 family 3 subfamily A polypeptide 4	5	0	0	5
G	3	0	0	3
cytochrome P450 2D6	3	0	0	3
Solute carrier family 22 member 2	0	2	0	2
Solute carrier family 22 member 1	0	2	0	2
ATP-binding cassette sub-family C member 3	0	8	0	8
Multidrug resistance-associated protein 4	0	8	0	8
Solute carrier family 22 member 3	0	1	0	1
Interferon beta	3	0	0	3
HLA class I histocompatibility antigen, B alpha chain	3	0	0	3
Albumin	0	0	0	6
Gag-Pol polyprotein	0	4	0	4
Gag-Pol polyprotein	0	1	0	1
Gag-Pol polyprotein	0	2	0	2
Gag polyprotein	0	1	0	1
Gag-Pol polyprotein	0	3	0	3
ATP-dependent translocase ABCB1	0	4	0	4
Replicase polyprotein 1ab	0	3	1	4
Replicase polyprotein 1ab	0	4	1	5
Cytochrome P450 2D6	0	1	0	1
Gag-Pol polyprotein	0	3	0	3
Alpha-1B adrenergic receptor	0	6	0	6
Substance-K receptor	0	4	0	4
Alpha-1D adrenergic receptor	0	3	0	3
Thromboxane-A synthase	0	4	0	4
Gag-Pol polyprotein	0	3	0	3
Alpha-1A adrenergic receptor	0	6	0	6
Thromboxane-A synthase	0	0	0	1
Genome polyprotein	0	1	0	1
Solute carrier family 22 member 1	0	2	0	3
Protease	0	6	3	13
Multidrug and toxin extrusion protein 2	0	1	0	1
Inositol hexakisphosphate kinase 1	3	0	0	3
Canalicular multispecific organic anion transporter 1	0	5	0	5
Multidrug and toxin extrusion protein 1	0	3	0	3
Protease	0	6	4	11
Protease	0	1	0	1
cytochrome P450 2C9, partial	3	0	0	3
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, Leucine Aminopeptidase	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	2	0	2
Intestinal-type alkaline phosphatase	0	2	0	2
Proton-coupled amino acid transporter 1	0	1	0	2
Phospholipase A-2-activating protein	0	2	0	2
Glucagon-like peptide 1 receptor	0	2	2	4
Chain A, protease	0	1	0	1
Chain B, protease	0	1	0	1
Chain A, protease	0	0	1	1
Chain B, protease	0	0	1	1
Chain A, protease	0	0	1	1
Chain B, protease	0	0	1	1
Chain A, protease	0	0	1	1
Chain B, protease	0	0	1	1
Chain A, protease	0	0	1	1
Chain B, protease	0	0	1	1
Chain A, protease	0	0	1	1
Chain B, protease	0	0	1	1
Chain A, Protease	0	1	0	1
Chain B, Protease	0	1	0	1
Chain A, Protease	0	1	0	1
Chain B, Protease	0	1	0	1
Chain A, Protease	0	1	0	1
Chain B, Protease	0	1	0	1
Chain A, PROTEASE RETROPEPSIN	0	1	0	1
Chain B, PROTEASE RETROPEPSIN	0	1	0	1
Chain A, Protease Retropepsin	0	1	0	1
Chain B, Protease Retropepsin	0	1	0	1
Chain A, Protease Retropepsin	0	1	0	1
Chain B, Protease Retropepsin	0	1	0	1
RAR-related orphan receptor gamma	4	0	0	4
Fumarate hydratase	1	0	0	1
Smad3	3	0	0	3
progesterone receptor	3	0	0	3
EWS/FLI fusion protein	4	0	0	4
farnesoid X nuclear receptor	4	0	0	4
polyprotein	1	0	0	1
67.9K protein	3	0	0	3
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	5	0	0	5
nuclear receptor subfamily 1, group I, member 2	2	0	0	2
Spike glycoprotein	0	0	1	1
Replicase polyprotein 1ab	0	1	1	2
potassium voltage-gated channel subfamily H member 2 isoform d	1	0	0	1
nuclear receptor ROR-gamma isoform 1	4	0	0	4
peripheral myelin protein 22	5	0	0	5
Transmembrane protease serine 2	0	0	1	1
Gag-Pol polyprotein	0	1	0	1
Procathepsin L	0	0	1	1
Replicase polyprotein 1a	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Spike glycoprotein	3	0	1	4
Potassium voltage-gated channel subfamily H member 2	0	3	0	3
CAAX prenyl protease 1 homolog	0	1	0	1
Plasmepsin V	0	1	0	1
ATPase family AAA domain-containing protein 5	3	0	0	3
Ataxin-2	3	0	0	3
Angiotensin-converting enzyme 2	0	0	1	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	3	0	3
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	3	0	0	3
Dihydrofolate reductase	0	3	0	3
Dipeptidyl peptidase 4	0	1	0	1
Chain A, ASPARTYLPROTEASE	0	1	0	1
Chain B, ASPARTYLPROTEASE	0	1	0	1
glp-1 receptor, partial	2	0	0	2
nonstructural protein 1	1	0	0	1
IDH1	2	0	0	2
nuclear factor erythroid 2-related factor 2 isoform 2	1	0	0	1
DNA polymerase beta	1	0	0	1
urokinase-type plasminogen activator precursor	1	0	0	1
plasminogen precursor	1	0	0	1
urokinase plasminogen activator surface receptor precursor	1	0	0	1
Epidermal growth factor receptor	0	1	0	1
Tyrosine-protein kinase Lck	0	1	0	1
Tyrosine-protein kinase Fyn	0	1	0	1
Aldo-keto reductase family 1 member B1	0	2	0	2
Muscarinic acetylcholine receptor M5	0	2	0	2
Adenosine receptor A3	0	4	0	4
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Beta-3 adrenergic receptor	0	2	0	2
Androgen receptor	0	4	0	5
Potassium voltage-gated channel subfamily E member 1	0	1	0	1
Cytochrome P450 3A5	0	2	1	3
ATP-dependent translocase ABCB1	0	1	0	1
D(1A) dopamine receptor	0	2	0	2
Sodium-dependent noradrenaline transporter	0	2	0	2
Cruzipain	0	1	0	1
Mitogen-activated protein kinase 3	0	1	0	1
Mu-type opioid receptor	0	2	0	2
Delta-type opioid receptor	0	2	0	2
Kappa-type opioid receptor	0	2	0	2
Potassium voltage-gated channel subfamily KQT member 1	0	1	0	1
Sodium-dependent dopamine transporter	0	2	0	2
TAR DNA-binding protein 43	1	0	0	1
Sodium channel protein type 5 subunit alpha	0	1	0	1
Mitogen-activated protein kinase 14	0	1	1	2
Potassium voltage-gated channel subfamily D member 3	0	1	0	1
Chain A, Fatty acid-binding protein, adipocyte	0	1	0	1
acetylcholinesterase	2	0	0	2
Acetylcholinesterase	0	1	0	1
Toll-like receptor 2	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Fatty acid-binding protein, adipocyte	0	2	1	3
Tyrosine-protein phosphatase non-receptor type 1	0	4	0	4
Prostaglandin G/H synthase 2	0	1	0	1
Fatty acid-binding protein 5	0	2	1	3
Olfactory receptor 51E2	0	0	1	1
Transient receptor potential cation channel subfamily V member 2	0	1	0	1
aldehyde dehydrogenase 1 family, member A1	1	0	0	1
CDGSH iron-sulfur domain-containing protein 1	0	2	0	2
tyrosine-protein kinase Yes	1	0	0	1
Free fatty acid receptor 1	0	0	2	2
Bile salt export pump	0	3	0	3
Peroxisome proliferator-activated receptor gamma	0	1	0	1
Muscarinic acetylcholine receptor M1	0	0	3	3
Muscarinic acetylcholine receptor M3	0	0	3	3
Muscarinic acetylcholine receptor M4	0	0	3	3
Steryl-sulfatase	0	1	0	1
Muscarinic acetylcholine receptor M5	0	0	3	3
Muscarinic acetylcholine receptor M2	0	0	3	3
Carnitine O-palmitoyltransferase 2, mitochondrial	0	2	0	2
Amine oxidase [flavin-containing] B	0	3	0	3
Amine oxidase [flavin-containing] A	0	3	0	3
Amine oxidase [flavin-containing] A	0	3	0	3
Carnitine O-palmitoyltransferase 2, mitochondrial	0	2	0	2
Amine oxidase [flavin-containing] B	0	6	0	6
Carnitine O-palmitoyltransferase 1, liver isoform	0	2	0	2
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
CDGSH iron-sulfur domain-containing protein 2	0	2	0	2
CDGSH iron-sulfur domain-containing protein 1	0	4	0	4
Chain A, HADH2 protein	1	0	0	1
Chain B, HADH2 protein	1	0	0	1
Chain A, 2-oxoglutarate Oxygenase	2	0	0	2
thyrotropin-releasing hormone receptor	1	0	0	1
v-jun sarcoma virus 17 oncogene homolog (avian)	2	0	0	2
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	1	0	0	1
Cytochrome P450 2C9	0	1	1	2
Catechol O-methyltransferase	0	0	1	1
C-C chemokine receptor type 2	0	1	0	1
Cannabinoid receptor 2	0	0	1	1
Mu-type opioid receptor	0	1	0	1
ATP-binding cassette sub-family C member 8	0	2	0	2
ATP-sensitive inward rectifier potassium channel 11	0	2	0	2
Sodium/bile acid cotransporter	0	1	0	1
Thrombin	0	0	1	1
Met repressor	0	0	2	2
Protein arginine N-methyltransferase 5	0	0	1	1
Histone H3K27 methylase	0	0	0	1
Phenylethanolamine N-methyltransferase	0	0	1	2
S-adenosylmethionine decarboxylase proenzyme	0	1	0	2
Protein-L-isoaspartate(D-aspartate) O-methyltransferase	0	1	0	1
Catechol O-methyltransferase	0	0	0	1
Protein arginine N-methyltransferase 1	0	1	0	1
Methylosome protein 50	0	0	1	1
Chain A, Mineralocorticoid receptor	0	1	0	1
Chain A, Mineralocorticoid receptor	0	1	0	1
pregnane X receptor	1	0	0	1
activating transcription factor 6	2	0	0	2
Histone H2A.x	2	0	0	2
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	1	0	0	1
Vpr	1	0	0	1
Estrogen receptor	0	2	1	3
Glucocorticoid receptor	0	2	1	3
Progesterone receptor	0	2	1	3
Glycine receptor subunit alpha-1	0	2	0	2
Mineralocorticoid receptor	0	2	0	3
Androgen receptor	0	2	1	3
Glycine receptor subunit beta	0	2	0	2
Glycine receptor subunit alpha-2	0	2	0	2
Glycine receptor subunit alpha-3	0	2	0	2
Sodium-dependent serotonin transporter	0	1	0	1
Cytochrome P450 2C19	0	1	0	1
Estrogen receptor beta	0	1	1	2
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
UDP-glucuronosyltransferase 2B7	0	0	0	1
UDP-glucuronosyltransferase 1A4	0	0	0	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	1	3
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Splicing factor 3B subunit 3	0	1	0	1
Solute carrier organic anion transporter family member 1B1	0	1	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	1	0	0	1
Chain A, ATP-DEPENDENT DNA HELICASE Q1	1	0	0	1
regulator of G-protein signaling 4	1	0	0	1
thyroid stimulating hormone receptor	2	0	0	2
vitamin D3 receptor isoform VDRA	1	0	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	1	0	0	1
UDP-glucuronosyltransferase 1-6	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	0	0	1
Mitogen-activated protein kinase 1	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	1
5-hydroxytryptamine receptor 2B	0	2	0	2
Forkhead box protein M1	0	2	0	2
Indoleamine 2,3-dioxygenase 2	0	1	0	1
UDP-glucuronosyltransferase 1A10	0	0	0	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
thioredoxin glutathione reductase	1	0	0	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	1	0	0	1
Myeloperoxidase	0	1	0	1
Stromelysin-1	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	2
Substance-P receptor	0	1	0	1
Tryptophan 2,3-dioxygenase	0	1	0	2
SLC16A10 protein	0	0	0	1
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Tryprostatin B synthase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Monocarboxylate transporter 10	0	0	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Lipodystrophy, Familial Partial

Synonyms(1)

Research Excerpts

Overview

Research

Studies (55)

Protein Targets (466)

Lipodystrophy, Familial Partial

Synonyms(1)

Research Excerpts

Overview

Research

Studies (55)

Drugs Studied (36)

Protein Targets (466)