Page last updated: 2024-09-28

Leprosy, Macular

A principal or polar form of LEPROSY in which the skin lesions are few and are sharply demarcated. Peripheral nerve involvement is pronounced and may be severe. Unlike lepromatous leprosy (LEPROSY, LEPROMATOUS), the lepromin test is positive. Tuberculoid leprosy is rarely a source of infection to others.

Synonyms(4)

Synonym
Leprosy, Neural
Tuberculoid Leprosy
Leprosy, Macular
Leprosy, Tuberculoid

Research Excerpts

Overview

ExcerptReference
"Tuberculoid leprosy is frequently recognized as the benign polar form of the disease, while lepromatous leprosy is regarded as the malignant form."( Aguilar-Santelises, M; Arce-Paredes, P; Hernandez, VG; Juarez-Ortega, M; Rojas-Espinosa, O; Villanueva, EB, 2015)

Treatment

ExcerptReference
"Thirty nine cases of borderline tuberculoid leprosy having nerve abscesses (15 with sinuses) were treated with daily dose of rifampicin and isoniazid for six months along with standard multidrug therapy."( Husain, S; Malaviya, GN; Mishra, B, 1997)
"A 35-year-old man with borderline tuberculoid leprosy developed Type I lepra reaction 12 days after anti-leprosy treatment."( Kalita, J; Mahadevan, A; Misra, UK; Shankar, SK, 2003)
"We present a case of isolated tuberculoid leprosy, discuss the occurrence, the differential diagnosis and the treatment of this rare presentation and reaffirm the importance of considering leprosy in the differential diagnosis of patients with polyneuropathy or nerve enlargement with no skin lesions."( Carvalho, AA; Martins, RS; Siqueira, MG, 2004)

Research

Studies (219)

TimeframeStudies, This Condition (%)All Conditions %
pre-199039 (17.81)23.3326
1990's101 (46.12)12.5806
2000's50 (22.83)18.1394
2010's27 (12.33)28.8240
2020's2 (0.91)9.53
DrugIndicatedRelationship StrengthStudiesTrials
dinitrochlorobenzene0low20
acetic acid0low10
salicylic acid0low10
lactic acid0low10
formaldehyde0low10
niacin0low20
nitrites0low10
chloroquine0low10
ciprofloxacin0low10
clofazimine0medium193
dapsone0medium632
furosemide0low10
guaifenesin0low10
hydroxychloroquine0low10
isoniazid0low40
2-propanol0low10
ketoconazole0low10
ofloxacin0medium41
pentoxifylline0medium11
phenylbutazone0low10
thalidomide0medium21
trimethoprim0low10
prednisolone0low120
thymidine0low10
prednisone0low80
serine0low10
levodopa0low10
tyrosine0low10
leucine0low10
methionine0low10
tryptophan0low10
arginine0low10
triamcinolone acetonide0low10
triethanolamine0low10
meglumine0low20
fusarium0low10
reticulin0low20
pyrazon0low10
trolamine salicylate0low20
tetradecanoylphorbol acetate0medium11
phenyl acetate0low10
triamcinolone0low10
chloroquine diphosphate0low10
meglumine antimoniate0low10
peroxynitrous acid0low10
methotrexate0low10
cortisone0low10
3-nitrotyrosine0low10
monensin0low10
prothionamide0low30
1-methyltryptophan0low10
buthionine0low10
ethionamide0medium11
isoprodian0low10
bilirubin0low10
phenylephrine hydrochloride0low10
i(3)so3-galactosylceramide0low10
sq-233770low10
acid phosphatase0low10
oligonucleotides0low10
glycolipids0medium182
tuftsin0low30
minocycline0low30
transforming growth factor beta0low40
muramidase0low10
exudates0low20
neopterin0medium11
rifampin0medium583
eye0low10
concanavalin a0low20

Protein Targets (785)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Dihydrofolate reductase0708
Indoleamine 2,3-dioxygenase 10417
Adenosine receptor A10215
Indoleamine 2,3-dioxygenase 10101
Tryptophan 2,3-dioxygenase0101
Indoleamine 2,3-dioxygenase 20202
hypoxia-inducible factor 1 alpha subunit5005
RAR-related orphan receptor gamma150015
GLI family zinc finger 3170017
AR protein260026
aldehyde dehydrogenase 1 family, member A1170017
retinoic acid nuclear receptor alpha variant 1150015
retinoid X nuclear receptor alpha160016
estrogen nuclear receptor alpha340034
peroxisome proliferator-activated receptor delta100010
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a8008
activating transcription factor 64004
v-jun sarcoma virus 17 oncogene homolog (avian)8008
Histone H2A.x5005
thyroid hormone receptor beta isoform a5005
heat shock protein beta-16006
nuclear factor erythroid 2-related factor 2 isoform 1160016
lamin isoform A-delta10180018
Voltage-dependent calcium channel gamma-2 subunit8008
Glutamate receptor 28008
Chain A, Putative fructose-1,6-bisphosphate aldolase2002
Chain A, JmjC domain-containing histone demethylation protein 3A6006
phosphopantetheinyl transferase110011
bromodomain adjacent to zinc finger domain 2B6006
euchromatic histone-lysine N-methyltransferase 2230023
pyruvate kinase PKM isoform a1001
geminin200020
Glycoprotein hormones alpha chain1001
Guanine nucleotide-binding protein G1001
Tubulin--tyrosine ligase0202
Free fatty acid receptor 30011
Free fatty acid receptor 20112
Tyrosine-protein kinase Lck0112
Tyrosine-protein kinase Fyn0112
Fibrinogen C domain-containing protein 10101
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE160016
Chain A, Membrane lipoprotein tmpC0011
Chain A, Membrane lipoprotein tmpC0011
Chain A, Membrane lipoprotein tmpC0011
Chain A, Structure of PAE2307 in complex with adenosine0011
Chain B, Structure of PAE2307 in complex with adenosine0011
Chain A, ADENOSINE RECEPTOR A2A0101
Chain A, ADENOSINE RECEPTOR A2A0101
Chain A, tRNA (guanine-N(1)-)-methyltransferase0011
Chain A, Uncharacterized protein MJ08830011
signal transducer and activator of transcription 6, interleukin-4 induced1001
regulator of G-protein signaling 44004
glucocorticoid receptor [Homo sapiens]200020
NPYLR7B0011
arylsulfatase A9009
IDH17007
glycogen synthase kinase-3 beta isoform 10022
mitogen-activated protein kinase 14004
flap endonuclease 19009
nuclear receptor ROR-gamma isoform 16006
peripheral myelin protein 227007
survival motor neuron protein isoform d9009
high affinity choline transporter 1 isoform a0101
Sodium/nucleoside cotransporter 10202
Calcium dependent protein kinase0101
Mitogen-activated protein kinase kinase kinase 70011
Sodium/nucleoside cotransporter 20202
Rap guanine nucleotide exchange factor 34004
Purine nucleoside phosphorylase0101
Epidermal growth factor receptor0202
Phosphoglycerate kinase 1 0101
Adenosine deaminase0001
Avidin0011
Adenosine deaminase0001
Glyceraldehyde-3-phosphate dehydrogenase0202
Receptor tyrosine-protein kinase erbB-20101
Insulin receptor0001
Phosphoglycerate kinase 20101
Heat shock protein HSP 90-alpha0112
Platelet-derived growth factor receptor beta0001
Adenosine receptor A30326
Heat shock 70 kDa protein 1A 0101
Heat shock cognate 71 kDa protein0011
Fibroblast growth factor receptor 10001
Inosine-5'-monophosphate dehydrogenase 20101
Endoplasmin0112
Inosine-5'-monophosphate dehydrogenase 1 0101
Fibroblast growth factor receptor 20001
Fibroblast growth factor receptor 40001
Fibroblast growth factor receptor 30001
Streptavidin0011
Adenosylhomocysteinase0003
Adenosine receptor A30101
Adenosine receptor A2a0225
Adenosine receptor A2b0113
Adenosine receptor A2b0112
Adenylate kinase 2, mitochondrial0101
Adenosine receptor A10326
Adenosine receptor A2a0114
Adenylate kinase isoenzyme 1 0101
Phosphatidylinositol 4-kinase alpha0203
Adenosine receptor A10112
Adenosine kinase0001
Adenosine deaminase 0001
Equilibrative nucleoside transporter 20202
Phosphatidylinositol 4-kinase type 2-beta0203
Histone-lysine N-methyltransferase, H3 lysine-79 specific0101
Equilibrative nucleoside transporter 10202
Phosphatidylinositol 4-kinase type 2-alpha0203
Solute carrier family 28 member 30202
Adenosine kinase0102
Phosphatidylinositol 4-kinase beta0203
5-methylthioadenosine/S-adenosylhomocysteine deaminase0001
Adenosine transporter 10001
Chain A, 2-oxoglutarate Oxygenase140014
Microtubule-associated protein tau9009
thioredoxin glutathione reductase6006
Smad35005
microphthalmia-associated transcription factor isoform 90101
Carbonic anhydrase 106010
Carbonic anhydrase 206111
Tyrosine-protein phosphatase non-receptor type 10114
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
thioredoxin reductase120012
NFKB1 protein, partial5005
GLS protein7007
thyroid stimulating hormone receptor9009
alpha-galactosidase3003
cytochrome P450 2C19 precursor4004
chromobox protein homolog 1140014
DNA polymerase iota isoform a (long)9009
muscarinic acetylcholine receptor M18008
lethal factor (plasmid)5005
Cytochrome P450 3A40608
Nitric oxide synthase, endothelial0002
Nitric oxide synthase, brain0001
Nitric oxide synthase, brain 0001
Nitric oxide synthase, inducible0001
Nitric oxide synthase, inducible0013
Cationic amino acid transporter 30101
ATP-dependent phosphofructokinase6006
Chain A, Hyaluronidase, phage associated0101
acetylcholinesterase5005
cytochrome P450 family 3 subfamily A polypeptide 4130013
estrogen-related nuclear receptor alpha170017
vitamin D (1,25- dihydroxyvitamin D3) receptor150015
nuclear factor erythroid 2-related factor 2 isoform 2110011
thyroid hormone receptor beta isoform 2110011
lethal(3)malignant brain tumor-like protein 1 isoform I1001
Polyphenol oxidase 206011
Pancreatic alpha-amylase0202
Albumin0101
Urease0101
Prolyl 4-hydroxylase subunit alpha-10001
Tyrosinase0202
Alpha-2B adrenergic receptor0415
Spike glycoprotein91313
Hyaluronate lyase0101
Prolyl hydroxylase EGLN20001
Egl nine homolog 10001
Prolyl hydroxylase EGLN30001
Hypoxia-inducible factor 1-alpha inhibitor0001
Solute carrier family 23 member 10101
Chain A, TYROSYL-DNA PHOSPHODIESTERASE7007
Chain A, HADH2 protein110011
Chain B, HADH2 protein110011
Chain A, Cruzipain3003
USP1 protein, partial6006
vitamin D3 receptor isoform VDRA7007
DNA polymerase kappa isoform 16006
caspase-1 isoform alpha precursor2002
Caspase-72002
Inositol monophosphatase 13003
Solute carrier organic anion transporter family member 1B30408
Solute carrier organic anion transporter family member 1B10407
PPM1D protein1001
TDP1 protein180018
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase0101
Spike glycoprotein0134
Replicase polyprotein 1ab0134
glucose-6-phosphate 1-dehydrogenase isoform b0101
Transmembrane protease serine 20134
ATP-binding cassette sub-family C member 3017017
Multidrug resistance-associated protein 4018020
Bile salt export pump024024
Dihydrofolate reductase 0303
DNA ligase0101
Interferon beta7007
Riboflavin-binding protein0011
Major prion protein0011
Amyloid-beta precursor protein0202
Histidine-rich protein PFHRP-II0102
Procathepsin L0134
Muscarinic acetylcholine receptor M20505
Muscarinic acetylcholine receptor M40202
Muscarinic acetylcholine receptor M50202
Alpha-2A adrenergic receptor0404
Replicase polyprotein 1a0134
Replicase polyprotein 1ab0134
Replicase polyprotein 1ab0235
Spike glycoprotein0112
Replicase polyprotein 1ab0235
Muscarinic acetylcholine receptor M10202
Ribosyldihydronicotinamide dehydrogenase [quinone]0101
Alpha-2C adrenergic receptor0202
DNA ligase 10101
Muscarinic acetylcholine receptor M30202
Serine/threonine-protein kinase mTOR0101
Nuclear receptor subfamily 4 group A member 20011
Beta-secretase 10101
Calcium-dependent protein kinase 10011
MO15-related protein kinase Pfmrk 0101
DNA ligase A0101
Potassium voltage-gated channel subfamily H member 2010011
Sigma intracellular receptor 20202
Phosphoethanolamine N-methyltransferase0101
Canalicular multispecific organic anion transporter 1017017
Ataxin-28008
Sigma non-opioid intracellular receptor 10202
Angiotensin-converting enzyme 2 0134
Cysteine proteinase falcipain 2a 0101
Cysteine proteinase falcipain 2a 0101
endonuclease IV5005
GALC protein3003
nuclear receptor subfamily 1, group I, member 3100010
progesterone receptor100010
cytochrome P450 2D66006
potassium voltage-gated channel subfamily H member 2 isoform d5005
EWS/FLI fusion protein110011
cytochrome P450 2C9 precursor3003
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 15005
Gamma-aminobutyric acid receptor subunit pi92011
Cytochrome P450 1A20202
DNA gyrase subunit B0101
DNA gyrase subunit A0101
DNA gyrase subunit B0102
DNA gyrase subunit A0306
DNA gyrase subunit B0306
DNA topoisomerase 4 subunit A0101
DNA topoisomerase 4 subunit B0102
DNA topoisomerase 4 subunit A0102
Cytochrome P450 2D60101
DNA topoisomerase 2-alpha0104
Cytochrome P450 2C9 0819
Gamma-aminobutyric acid receptor subunit beta-192011
Gamma-aminobutyric acid receptor subunit delta92011
Gamma-aminobutyric acid receptor subunit gamma-292011
Gamma-aminobutyric acid receptor subunit alpha-592011
Gamma-aminobutyric acid receptor subunit alpha-392011
DNA gyrase subunit A0102
Gamma-aminobutyric acid receptor subunit gamma-192011
Gamma-aminobutyric acid receptor subunit alpha-292011
Gamma-aminobutyric acid receptor subunit alpha-492011
Gamma-aminobutyric acid receptor subunit gamma-392011
Gamma-aminobutyric acid receptor subunit alpha-692011
Cytochrome P450 2C190202
Multidrug resistance protein MdtK0011
Histamine H2 receptor5005
Gamma-aminobutyric acid receptor subunit alpha-192011
Gamma-aminobutyric acid receptor subunit beta-392011
Gamma-aminobutyric acid receptor subunit beta-292011
DNA gyrase subunit B0405
DNA gyrase subunit A0405
Enoyl-[acyl-carrier-protein] reductase [NADH]0205
DNA topoisomerase 4 subunit A0101
DNA topoisomerase 4 subunit B0101
Integrase 0101
GABA theta subunit92011
Gamma-aminobutyric acid receptor subunit epsilon92011
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)8008
G4004
67.9K protein7007
cytochrome P450 2D6 isoform 13003
transcriptional regulator ERG isoform 32002
importin subunit beta-1 isoform 13003
mitogen-activated protein kinase kinase kinase kinase 2 isoform 10011
eyes absent homolog 2 isoform a1001
snurportin-13003
GTP-binding nuclear protein Ran isoform 11001
streptokinase A precursor0022
mitogen-activated protein kinase kinase kinase 3 isoform 10011
HLA class I histocompatibility antigen, B alpha chain 4004
Estrogen receptor0011
ATP-dependent translocase ABCB10404
5-hydroxytryptamine receptor 1A0011
Cruzipain0101
C-terminal-binding protein 11001
Estrogen receptor beta0011
Inositol hexakisphosphate kinase 14004
Broad substrate specificity ATP-binding cassette transporter ABCG20304
cytochrome P450 2C9, partial4004
dopamine D1 receptor5005
pregnane X receptor4004
pregnane X nuclear receptor110011
peroxisome proliferator activated receptor gamma100010
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a6006
peripheral myelin protein 22 isoform 16006
atrial natriuretic peptide receptor 1 precursor3003
cytochrome P450 3A4 isoform 19009
M-phase phosphoprotein 86006
Glucocorticoid receptor010217
Sex hormone-binding globulin0011
Glycine receptor subunit alpha-1010010
Corticosteroid-binding globulin0202
Glycine receptor subunit beta010010
Glycine receptor subunit alpha-2010010
Glycine receptor subunit alpha-3010010
Potassium voltage-gated channel subfamily A member 10011
TAR DNA-binding protein 436006
Multidrug and toxin extrusion protein 10404
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase 0101
interleukin 84004
muscleblind-like protein 1 isoform 14004
Bile salt export pump0909
Myeloperoxidase0303
Dihydrofolate reductase0506
5-hydroxytryptamine receptor 60202
Nuclear receptor ROR-gamma4004
Solute carrier organic anion transporter family member 1A40102
Solute carrier organic anion transporter family member 1A50001
Steryl-sulfatase0001
Multidrug resistance-associated protein 1 0002
Solute carrier organic anion transporter family member 1A10102
Solute carrier organic anion transporter family member 1A20102
Solute carrier organic anion transporter family member 1A30002
G-protein coupled bile acid receptor 10011
ATP-binding cassette sub-family C member 110002
Solute carrier family 22 member 110002
Solute carrier organic anion transporter family member 1A10001
Solute carrier organic anion transporter family member 1B20001
Chain A, Beta-lactamase5005
glp-1 receptor, partial5005
SMAD family member 25005
ATAD5 protein, partial7007
SMAD family member 35005
apical membrane antigen 1, AMA13003
caspase 7, apoptosis-related cysteine protease2002
estrogen receptor 2 (ER beta)7007
farnesoid X nuclear receptor7007
caspase-32002
aryl hydrocarbon receptor7007
thyroid stimulating hormone receptor5005
parathyroid hormone/parathyroid hormone-related peptide receptor precursor5005
urokinase-type plasminogen activator precursor3003
plasminogen precursor3003
urokinase plasminogen activator surface receptor precursor3003
Vpr2002
Cellular tumor antigen p53110011
Glutathione S-transferase omega-10202
ATPase family AAA domain-containing protein 56006
DNA polymerase beta2002
thyrotropin-releasing hormone receptor2002
Solute carrier family 22 member 60202
Carbonic anhydrase 120206
Albumin0235
Carbonic anhydrase 30205
Glucose-6-phosphate 1-dehydrogenase0303
Carbonic anhydrase 40307
Carbonic anhydrase 60206
Serum paraoxonase/arylesterase 10101
Corticosteroid 11-beta-dehydrogenase isozyme 10101
Carbonic anhydrase 5A, mitochondrial0206
Carbonic anhydrase 70206
Corticosteroid 11-beta-dehydrogenase isozyme 10101
Cytochrome P450 2J20505
6-phosphogluconate dehydrogenase, decarboxylating0202
Holo-[acyl-carrier-protein] synthase0101
Solute carrier organic anion transporter family member 2A10101
Sodium/bile acid cotransporter0202
Carbonic anhydrase 90206
Carbonic anhydrase 130205
G-protein coupled receptor 350112
CDGSH iron-sulfur domain-containing protein 10202
Carbonic anhydrase 140206
Carbonic anhydrase 5B, mitochondrial0206
Genome polyprotein 0101
Alpha-1D adrenergic receptor0202
Cyclic GMP-AMP synthase0101
Toll-like receptor 90101
Toll-like receptor 70101
Luciferase4004
3-oxoacyl-[acyl-carrier-protein] synthase 3 0101
histone acetyltransferase KAT2A isoform 16006
N-glycosylase/DNA lyase0101
Formamidopyrimidine-DNA glycosylase0101
Cytochrome P450 2C80202
Cytochrome P450 2A60101
Macrophage migration inhibitory factor0101
Endonuclease III-like protein 10101
Pantothenate synthetase0101
Isocitrate lyase0101
Putative FAD-containing monooxygenase MymA0101
Dihydrofolate reductase0303
Endonuclease 8-like 10101
3-oxoacyl-[acyl-carrier-protein] synthase 30101
Gap junction alpha-1 protein0101
Gap junction beta-2 protein0101
Acyl-protein thioesterase 10101
Estrogen receptor beta0102
Solute carrier family 22 member 1 0202
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial0101
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial0202
Cytochrome P450 26A10101
Prostaglandin G/H synthase 1 0101
Prostaglandin G/H synthase 2 0101
3',5'-cyclic-AMP phosphodiesterase 0101
Camphor 5-monooxygenase0001
Phospholipase A2, major isoenzyme0101
Chymotrypsinogen A0101
Beta-lactamase0101
Steroid 17-alpha-hydroxylase/17,20 lyase0202
ATP-dependent translocase ABCB10303
Epoxide hydrolase 10001
Aldo-keto reductase family 1 member B10202
Cytochrome P450 2C11 0101
Steroid 21-hydroxylase0101
Aromatase0202
Steroid 17-alpha-hydroxylase/17,20 lyase 0101
Polyunsaturated fatty acid 5-lipoxygenase0101
Polyunsaturated fatty acid lipoxygenase ALOX150303
Cholesterol side-chain cleavage enzyme, mitochondrial 0101
5-hydroxytryptamine receptor 2A0303
Cytochrome P450 2A20101
Cytochrome P450 11B1, mitochondrial 0202
Cytochrome P450 11B1, mitochondrial0101
Translocator protein0101
Cytochrome P450 7A1 0101
Cytochrome P450 11B2, mitochondrial0101
Estrogen receptor0102
ATP-dependent translocase ABCB10303
Substance-K receptor0202
UDP-glucuronosyltransferase 1A1 0101
Sodium-dependent noradrenaline transporter 0202
Thromboxane-A synthase 0101
Histamine H2 receptor0202
Gonadotropin-releasing hormone receptor0112
Sodium-dependent serotonin transporter0202
Type-1 angiotensin II receptor0101
Malate dehydrogenase, cytoplasmic0101
Delta-type opioid receptor0303
Cytochrome P450 4F20101
Sodium-dependent dopamine transporter 0202
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial0202
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial0101
Lanosterol 14-alpha demethylase0314
Cytochrome P450 7A10101
Lanosterol 14-alpha demethylase 0202
cellular tumor antigen p53 isoform a3003
Integrin beta-33003
Integrin alpha-IIb3003
Chain A, AMINOPEPTIDASE0101
Chain A, AMINOPEPTIDASE0101
Chain A, Leucine Aminopeptidase0101
Alkaline phosphatase, tissue-nonspecific isozyme0202
Intestinal-type alkaline phosphatase0202
Large neutral amino acids transporter small subunit 10505
Proton-coupled amino acid transporter 10203
Phospholipase A-2-activating protein0202
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
15-lipoxygenase, partial4004
WRN1001
integrase, partial0101
lens epithelium-derived growth factor p750101
pyruvate kinase1001
Bloom syndrome protein isoform 19009
hexokinase-4 isoform 11001
glucokinase regulatory protein1001
ubiquitin carboxyl-terminal hydrolase 2 isoform a3003
peptidyl-prolyl cis-trans isomerase NIMA-interacting 12002
DNA polymerase eta isoform 12002
Plasma kallikrein0003
Glutamate receptor ionotropic, NMDA 1 0003
Carbonic anhydrase0104
Solute carrier family 15 member 10101
Carbonic anhydrase0003
Glutamate receptor ionotropic, NMDA 2A 0003
Glutamate receptor ionotropic, NMDA 2B0003
Glutamate receptor ionotropic, NMDA 2C0003
SLC16A10 protein0003
Carbonic anhydrase 0003
Carbonic anhydrase-like protein, putative0003
Carbonic anhydrase0003
Carbonic anhydrase0003
Glutamate receptor ionotropic, NMDA 2D0003
Carbonic anhydrase 0003
Glutamate receptor ionotropic, NMDA 3B0003
Monocarboxylate transporter 100003
Carbonic anhydrase 150205
Glutamate receptor ionotropic, NMDA 3A0003
phosphoglycerate kinase1001
Chain A, Methionyl-tRNA synthetase0011
Chain A, Methionyl-tRNA synthetase0011
Chain A, Aminopeptidase0101
Chain A, Methionine aminopeptidase0101
S-ribosylhomocysteine lyase0101
Adenylate cyclase type 50001
S-adenosylmethionine synthase isoform type-10001
S-adenosylmethionine synthase isoform type-20001
Fatty acid synthase0101
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain A, Ferritin light chain3003
acid sphingomyelinase1001
ClpP1001
Thymidylate synthase 0101
Thymidylate synthase 0101
polyunsaturated fatty acid lipoxygenase ALOX121001
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0101
transactivating tegument protein VP16 [Human herpesvirus 1]0101
nuclear receptor coactivator 3 isoform a0101
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0304
Dihydrofolate reductase0303
Dihydrofolate reductase0101
Dihydrofolate reductase0405
Thymidylate synthase0101
Tyrosine-protein kinase ABL10011
Thymidylate synthase0303
Bifunctional dihydrofolate reductase-thymidylate synthase0303
Thymidylate synthase0203
5-hydroxytryptamine receptor 2C0102
High mobility group protein B10022
Dihydrofolate reductase0303
Thymidylate synthase0202
Dihydrofolate reductase0426
Bifunctional dihydrofolate reductase-thymidylate synthase0303
Folate receptor beta0101
Folate receptor alpha0101
Histidine decarboxylase0101
Trifunctional purine biosynthetic protein adenosine-30101
Cyclin-dependent kinase 20011
Bifunctional purine biosynthesis protein ATIC0202
Delta-type opioid receptor0101
Mu-type opioid receptor0101
Kappa-type opioid receptor0101
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
Pteridine reductase 10101
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0203
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Solute carrier family 22 member 60102
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Solute carrier family 22 member 200202
Dihydrofolate reductase 0303
Solute carrier family 22 member 80203
Solute carrier family 22 member 60202
Dihydrofolate reductase0203
Proton-coupled folate transporter0101
Multidrug resistance associated protein0102
Protein-arginine deiminase type-40606
Stromelysin-10213
Matrilysin0101
Multidrug transporter MdfA0101
Matrix metalloproteinase-90101
Protein mono-ADP-ribosyltransferase PARP150101
lysosomal alpha-glucosidase preproprotein2002
Neuronal acetylcholine receptor subunit alpha-42002
Cholesteryl ester transfer protein0101
Neuronal acetylcholine receptor subunit beta-22002
D-amino-acid oxidase0101
Xanthine dehydrogenase/oxidase0101
Hydroxycarboxylic acid receptor 30011
Nicotinamidase0101
Hydroxycarboxylic acid receptor 20011
Hydroxycarboxylic acid receptor 20213
D-aspartate oxidase0101
Hydroxycarboxylic acid receptor 20112
STE240001
CAAX prenyl protease0001
Trypsin0001
vasopressin V1b receptor1001
relaxin receptor 1 isoform 11001
cGMP-dependent 3',5'-cyclic phosphodiesterase0101
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A0101
cGMP-specific 3',5'-cyclic phosphodiesterase0101
Tumor necrosis factor0101
Cholinesterase0101
Acetylcholinesterase0202
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0202
Disintegrin and metalloproteinase domain-containing protein 172002
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0202
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0202
Chitotriosidase-10213
cGMP-inhibited 3',5'-cyclic phosphodiesterase A0101
Endochitinase B10213
Estrogen receptor 10101
nonstructural protein 11001
Parkin1001
D(1A) dopamine receptor2002
fMet-Leu-Phe receptor0101
neuropeptide S receptor isoform A2002
Prostaglandin G/H synthase 10202
Prostaglandin G/H synthase 20303
Prostaglandin G/H synthase 2 0101
Prostaglandin G/H synthase 1 0101
Nicotinate phosphoribosyltransferase0202
Cyclooxygenase-2 0101
beta-2 adrenergic receptor1001
mu-type opioid receptor isoform MOR-10011
5-hydroxytryptamine receptor 2A0011
Fumarate hydratase1001
Thrombopoietin2002
DNA polymerase III, partial1001
polyprotein1001
XBP10101
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)2002
Caspase-71001
caspase-31001
huntingtin isoform 21001
nuclear factor NF-kappa-B p105 subunit isoform 11001
ras-related protein Rab-9A1001
serine/threonine-protein kinase mTOR isoform 11001
DNA damage-inducible transcript 3 protein0101
Solute carrier family 22 member 20101
Polyunsaturated fatty acid lipoxygenase ALOX15B2002
Voltage-dependent T-type calcium channel subunit alpha-1G0011
Voltage-dependent L-type calcium channel subunit alpha-1F0202
Ubiquitin carboxyl-terminal hydrolase 10101
Potassium channel subfamily K member 20112
Sodium channel protein type 2 subunit alpha0101
D(2) dopamine receptor0112
D0101
D(3) dopamine receptor0101
Glycine receptor subunit alpha-10011
Sodium-dependent dopamine transporter0101
D(1B) dopamine receptor0101
D(4) dopamine receptor0101
5-hydroxytryptamine receptor 7 0101
Mu-type opioid receptor0101
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 4 subunit alpha0101
Kappa-type opioid receptor0101
D(1A) dopamine receptor1001
D(2) dopamine receptor0202
Sodium channel protein type 7 subunit alpha0101
Voltage-dependent L-type calcium channel subunit alpha-1D 0202
Voltage-dependent L-type calcium channel subunit alpha-1S0202
Voltage-dependent L-type calcium channel subunit alpha-1C0303
Sodium channel protein type 5 subunit alpha0101
Sodium channel protein type 9 subunit alpha0101
Multidrug and toxin extrusion protein 20101
WD repeat-containing protein 480101
Sodium channel protein type 2 subunit alpha0101
Histamine H4 receptor0101
Sodium channel protein type 3 subunit alpha0101
Sodium channel protein type 11 subunit alpha0101
Sodium channel protein type 8 subunit alpha0101
Sodium channel protein type 10 subunit alpha0101
luciferase0001
nuclear receptor subfamily 1, group I, member 22002
Fatty acid-binding protein, liver0101
Estrogen receptor0202
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Mineralocorticoid receptor 0213
Androgen receptor0202
Glutamine synthetase0011
Androgen receptor0101
Histamine H1 receptor0011
Nociceptin receptor0011
Estrogen receptor beta0202
NS5 0011
Polymerase basic protein 20011
RNA-directed RNA polymerase catalytic subunit0011
Polymerase acidic protein0022
Adenosine receptor A10101
Genome polyprotein0011
DNA-directed RNA polymerase subunit beta0101
Nuclear receptor subfamily 1 group I member 20011
Solute carrier organic anion transporter family member 2B1 0202
NH(3)-dependent NAD(+) synthetase0202
60 kDa heat shock protein, mitochondrial0101
Cytochrome P450 2B60011
Arylacetamide deacetylase0102
Caspase-10101
Alpha-synuclein0101
10 kDa heat shock protein, mitochondrial0101
DNA-directed RNA polymerase subunit beta0101
Thiosulfate sulfurtransferase0101
60 kDa chaperonin 0101
10 kDa chaperonin 0101
chaperonin-containing TCP-1 beta subunit homolog1001
Inhibitor of nuclear factor kappa-B kinase subunit beta0001
5'-AMP-activated protein kinase subunit beta-20001
Tyrosine-protein phosphatase YopH0101
Aldo-keto reductase family 1 member B10101
Prolyl 4-hydroxylase subunit alpha-10101
Prostaglandin G/H synthase 10101
Cystathionine gamma-lyase0101
5'-AMP-activated protein kinase subunit gamma-10001
5'-AMP-activated protein kinase catalytic subunit alpha-20001
Xanthine dehydrogenase/oxidase0101
5'-AMP-activated protein kinase catalytic subunit alpha-10001
Carbonic anhydrase0101
Solute carrier family 22 member 70001
Ubiquitin-like domain-containing CTD phosphatase 10101
5'-AMP-activated protein kinase subunit gamma-30001
5'-AMP-activated protein kinase subunit gamma-20001
5'-AMP-activated protein kinase subunit beta-10001
Acetylcholinesterase0101
Pyruvate kinase PKM0011
Neutral amino acid transporter A0101
Cholinesterase0101
Neutral amino acid transporter B(0)0101
Amino acid transporter0101
Serine/threonine-protein kinase D30011
Protein kinase C gamma type0112
Protein kinase C beta type0112
Luciferin 4-monooxygenase0011
Protein kinase C alpha type0112
Beta-1 adrenergic receptor0101
Protein kinase C eta type0011
Protein kinase C iota type0011
Protein kinase C epsilon type0112
Protein kinase C theta type0011
Protein kinase C zeta type0011
Protein kinase C delta type0112
Serine/threonine-protein kinase D10011
Ras guanyl-releasing protein 30011
Cereblon isoform 40202
Prostaglandin G/H synthase 20101
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0101
DNA-binding protein Ikaros0001
DNA damage-binding protein 10112
Protein cereblon0214
Thymidine kinase 0102
Thymidine kinase, cytosolic0204
Thymidine kinase0102
Thymidine phosphorylase0001
Polyunsaturated fatty acid 5-lipoxygenase0101
Thymidine phosphorylase0001
Thymidylate kinase0101
Thymidine kinase, cytosolic 0002
Thymidine kinase0001
Thymidylate kinase0101
Thymidine kinase 0102
Sterol O-acyltransferase 10101
Thymidine kinase0001
Thymidine kinase0001
procathepsin L isoform 1 preproprotein0101
Chain A, Dihydrofolate Reductase0011
Chain A, Dihydrofolate reductase0101
Chain A, dihydrofolate reductase (DHFR)0101
Chain A, Dihydrofolate reductase0101
Chain A, Dihydrofolate reductase0101
Dihydrofolate reductase 0102
Dihydrofolate reductase type 10102
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase type 1 from Tn40030101
Dipeptidyl peptidase 40101
Dihydrofolate reductase0101
Dipeptidyl peptidase 40101
5-hydroxytryptamine receptor 2B0101
Metabotropic glutamate receptor 50101
5-hydroxytryptamine receptor 70101
Mu-type opioid receptor0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Trace amine-associated receptor 50011
Dihydrofolate reductase 0101
Dihydrofolate reductase 0101
Chain A, Trp Rna-binding Attenuation Protein0011
Chain K, Trp Rna-binding Attenuation Protein0011
Chain B, tryptophanyl-tRNA synthetase0011
Chain C, Tryptophanyl-tRNA synthetase II0011
histone-lysine N-methyltransferase 2A isoform 2 precursor1001
Substance-P receptor0101
Tryptophan 2,3-dioxygenase0102
Uracil nucleotide/cysteinyl leukotriene receptor0101
Tryprostatin B synthase0001
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase0011
Chain A, CHORISMATE MUTASE0101
Chain A, TYROSYL-tRNA SYNTHETASE0011
Taste receptor type 2 member 140001
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]