| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| Chain A, Beta-lactamase | 1 | 0 | 0 | 1 |
| bromodomain adjacent to zinc finger domain 2B | 1 | 0 | 0 | 1 |
| geminin | 3 | 0 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit rho-1 | 0 | 1 | 0 | 1 |
| Glutamate receptor 1 | 0 | 3 | 1 | 4 |
| Glutamate receptor 2 | 0 | 3 | 1 | 4 |
| Glutamate receptor 3 | 0 | 2 | 1 | 3 |
| Glutamate receptor ionotropic, kainate 3 | 0 | 3 | 0 | 3 |
| Solute carrier family 15 member 1 | 0 | 1 | 0 | 1 |
| Glutamate receptor 4 | 0 | 3 | 1 | 4 |
| Solute carrier family 15 member 1 | 0 | 1 | 0 | 1 |
| Solute carrier family 15 member 2 | 0 | 1 | 0 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 3 | 0 | 0 | 3 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | 2 | 0 | 0 | 2 |
| Chain A, Ferritin light chain | 2 | 0 | 0 | 2 |
| phosphopantetheinyl transferase | 4 | 0 | 0 | 4 |
| aldehyde dehydrogenase 1 family, member A1 | 2 | 0 | 0 | 2 |
| arylsulfatase A | 1 | 0 | 0 | 1 |
| euchromatic histone-lysine N-methyltransferase 2 | 6 | 0 | 0 | 6 |
| Bloom syndrome protein isoform 1 | 3 | 0 | 0 | 3 |
| cytochrome P450 2C19 precursor | 1 | 0 | 0 | 1 |
| lethal factor (plasmid) | 1 | 0 | 0 | 1 |
| lamin isoform A-delta10 | 3 | 0 | 0 | 3 |
| Metabotropic glutamate receptor 6 | 0 | 1 | 2 | 4 |
| Excitatory amino acid transporter 4 | 0 | 2 | 0 | 2 |
| Glutamate transporter homolog | 0 | 0 | 1 | 1 |
| Carbonic anhydrase 1 | 0 | 1 | 0 | 3 |
| Carbonic anhydrase 2 | 0 | 1 | 0 | 3 |
| N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 1D | 0 | 0 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | 0 | 5 | 1 | 6 |
| Excitatory amino acid transporter 1 | 0 | 3 | 0 | 4 |
| Excitatory amino acid transporter 2 | 0 | 3 | 0 | 4 |
| Excitatory amino acid transporter 3 | 0 | 3 | 0 | 4 |
| Glutamate receptor ionotropic, NMDA 2A | 0 | 5 | 1 | 6 |
| Glutamate receptor ionotropic, NMDA 2B | 0 | 5 | 1 | 6 |
| Glutamate receptor ionotropic, NMDA 2C | 0 | 5 | 1 | 7 |
| Metabotropic glutamate receptor 1 | 0 | 1 | 2 | 4 |
| Metabotropic glutamate receptor 2 | 0 | 1 | 2 | 4 |
| Carbonic anhydrase-like protein, putative | 0 | 0 | 0 | 2 |
| Glutamate receptor ionotropic, NMDA 2D | 0 | 5 | 1 | 6 |
| Glutamate receptor ionotropic, NMDA 3B | 0 | 5 | 1 | 6 |
| Carbonic anhydrase 4 | 0 | 0 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 3A | 0 | 5 | 1 | 6 |
| thioredoxin reductase | 2 | 0 | 0 | 2 |
| ATAD5 protein, partial | 2 | 0 | 0 | 2 |
| NFKB1 protein, partial | 1 | 0 | 0 | 1 |
| GLI family zinc finger 3 | 3 | 0 | 0 | 3 |
| AR protein | 3 | 0 | 0 | 3 |
| regulator of G-protein signaling 4 | 3 | 0 | 0 | 3 |
| 67.9K protein | 2 | 0 | 0 | 2 |
| activating transcription factor 6 | 2 | 0 | 0 | 2 |
| D(1A) dopamine receptor | 2 | 0 | 0 | 2 |
| cytochrome P450 3A4 isoform 1 | 2 | 0 | 0 | 2 |
| histone acetyltransferase KAT2A isoform 1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | 2 | 1 | 1 | 4 |
| ATP-binding cassette sub-family C member 3 | 0 | 1 | 0 | 1 |
| Multidrug resistance-associated protein 4 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid type B receptor subunit 2 | 0 | 2 | 1 | 3 |
| Gamma-aminobutyric acid type B receptor subunit 2 | 0 | 2 | 0 | 2 |
| Bile salt export pump | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 2 | 1 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit delta | 2 | 1 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 2 | 1 | 2 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 2 | 1 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 2 | 1 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 2 | 1 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 2 | 1 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 2 | 1 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 2 | 1 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 2 | 1 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 2 | 1 | 2 | 5 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 2 | 1 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 2 | 1 | 2 | 5 |
| GABA theta subunit | 2 | 1 | 1 | 4 |
| Canalicular multispecific organic anion transporter 1 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | 2 | 1 | 1 | 4 |
| Gamma-aminobutyric acid type B receptor subunit 1 | 0 | 2 | 1 | 3 |
| Gamma-aminobutyric acid type B receptor subunit 1 | 0 | 1 | 0 | 1 |
| ATP-dependent phosphofructokinase | 1 | 0 | 0 | 1 |
| RAR-related orphan receptor gamma | 3 | 0 | 0 | 3 |
| GALC protein | 1 | 0 | 0 | 1 |
| flap endonuclease 1 | 1 | 0 | 0 | 1 |
| Cytochrome P450 1A2 | 0 | 1 | 0 | 1 |
| Cytochrome P450 3A4 | 0 | 1 | 0 | 1 |
| Neuronal acetylcholine receptor subunit alpha-4 | 0 | 1 | 1 | 2 |
| Cytochrome P450 2A6 | 0 | 1 | 0 | 1 |
| Neuronal acetylcholine receptor subunit beta-2 | 0 | 1 | 1 | 2 |
| Cytochrome P450 2A5 | 0 | 1 | 0 | 1 |
| Sodium- and chloride-dependent creatine transporter 1 | 0 | 1 | 0 | 1 |
| Proton-coupled amino acid transporter 1 | 0 | 1 | 0 | 1 |
| IDH1 | 1 | 0 | 0 | 1 |
| Deoxycytidine kinase | 0 | 0 | 0 | 1 |
| hypoxia-inducible factor 1 alpha subunit | 1 | 0 | 0 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | 1 | 0 | 0 | 1 |
| progesterone receptor | 2 | 0 | 0 | 2 |
| retinoic acid nuclear receptor alpha variant 1 | 2 | 0 | 0 | 2 |
| estrogen-related nuclear receptor alpha | 2 | 0 | 0 | 2 |
| estrogen nuclear receptor alpha | 3 | 0 | 0 | 3 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | 2 | 0 | 0 | 2 |
| Histone H2A.x | 2 | 0 | 0 | 2 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 1 | 0 | 0 | 1 |
| Eyes absent homolog 2 | 0 | 1 | 0 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | 1 | 0 | 0 | 1 |
| Voltage-dependent calcium channel gamma-2 subunit | 1 | 0 | 0 | 1 |
| Cellular tumor antigen p53 | 2 | 0 | 0 | 2 |
| Amyloid-beta precursor protein | 0 | 1 | 0 | 1 |
| Angiotensin-converting enzyme | 0 | 1 | 0 | 1 |
| Glutamate receptor 2 | 1 | 2 | 1 | 4 |
| Histamine H2 receptor | 1 | 0 | 0 | 1 |
| Metallo-beta-lactamase VIM-13 | 0 | 1 | 0 | 1 |
| Beta-lactamase | 0 | 1 | 0 | 1 |
| Beta-lactamase | 0 | 1 | 0 | 1 |
| Beta-lactamase VIM-1 | 0 | 1 | 0 | 1 |
| Chain A, GLUTAMATE RECEPTOR SUBUNIT 2 | 0 | 1 | 0 | 1 |
| Chain A, Glutamate Receptor Subunit 2 | 0 | 1 | 0 | 1 |
| Chain B, Glutamate Receptor Subunit 2 | 0 | 1 | 0 | 1 |
| Chain A, Slr1257 protein | 0 | 0 | 1 | 1 |
| Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] | 0 | 1 | 0 | 1 |
| glp-1 receptor, partial | 1 | 0 | 0 | 1 |
| GLS protein | 2 | 0 | 0 | 2 |
| TDP1 protein | 1 | 0 | 0 | 1 |
| beta-2 adrenergic receptor | 1 | 0 | 0 | 1 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | 2 | 0 | 0 | 2 |
| Metabotropic glutamate receptor 8 | 0 | 2 | 0 | 2 |
| Glutamate receptor ionotropic, NMDA 2D | 0 | 2 | 0 | 2 |
| Glutamate receptor ionotropic, NMDA 3B | 0 | 2 | 0 | 2 |
| Glutathione reductase, mitochondrial | 0 | 2 | 0 | 2 |
| Bifunctional aspartokinase/homoserine dehydrogenase 1 | 0 | 1 | 0 | 1 |
| Prothrombin | 0 | 0 | 1 | 1 |
| Integrin beta-3 | 0 | 0 | 1 | 1 |
| Integrin alpha-IIb | 0 | 0 | 1 | 1 |
| ATP-citrate synthase | 0 | 1 | 0 | 1 |
| Glutamate receptor 1 | 0 | 2 | 1 | 3 |
| Glutamate receptor 3 | 0 | 2 | 1 | 3 |
| Glutamate receptor 4 | 0 | 2 | 1 | 3 |
| Glutamate receptor ionotropic, kainate 1 | 0 | 2 | 1 | 3 |
| Metabotropic glutamate receptor 1 | 0 | 1 | 1 | 2 |
| Metabotropic glutamate receptor 2 | 0 | 0 | 1 | 1 |
| Metabotropic glutamate receptor 3 | 0 | 0 | 1 | 1 |
| Metabotropic glutamate receptor 4 | 0 | 1 | 1 | 2 |
| Metabotropic glutamate receptor 5 | 0 | 0 | 1 | 1 |
| Metabotropic glutamate receptor 6 | 0 | 0 | 1 | 1 |
| Metabotropic glutamate receptor 7 | 0 | 0 | 1 | 1 |
| Glutamate receptor ionotropic, kainate 1 | 0 | 1 | 1 | 2 |
| Metabotropic glutamate receptor 5 | 0 | 1 | 1 | 3 |
| Glutamate receptor ionotropic, kainate 2 | 0 | 2 | 1 | 3 |
| Metabotropic glutamate receptor 8 | 0 | 0 | 1 | 1 |
| Excitatory amino acid transporter 3 | 0 | 0 | 0 | 1 |
| Glutamate racemase | 0 | 0 | 0 | 1 |
| Metabotropic glutamate receptor 8 | 0 | 1 | 1 | 2 |
| Fatty-acid amide hydrolase 1 | 0 | 2 | 0 | 2 |
| Glutamate receptor ionotropic, kainate 4 | 0 | 2 | 0 | 2 |
| Glutamate carboxypeptidase 2 | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | 0 | 3 | 0 | 3 |
| Glutamate receptor ionotropic, NMDA 2A | 0 | 3 | 0 | 3 |
| Glutamate receptor ionotropic, kainate 2 | 0 | 1 | 1 | 2 |
| Glutamate receptor ionotropic, kainate 3 | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 2B | 0 | 3 | 0 | 3 |
| Metabotropic glutamate receptor 7 | 0 | 1 | 1 | 3 |
| Metabotropic glutamate receptor 3 | 0 | 1 | 1 | 3 |
| Metabotropic glutamate receptor 4 | 0 | 1 | 1 | 3 |
| Glutamate receptor ionotropic, NMDA 2C | 0 | 2 | 0 | 2 |
| Glutamate receptor ionotropic, kainate 5 | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, kainate 5 | 0 | 2 | 0 | 2 |
| Glutamate racemase | 0 | 0 | 0 | 1 |
| Prolyl 4-hydroxylase | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 3A | 0 | 2 | 0 | 2 |
| Alpha-ketoglutarate-dependent dioxygenase FTO | 0 | 1 | 0 | 1 |
| N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 | 0 | 1 | 0 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | 1 | 0 | 0 | 1 |
| transcriptional regulator ERG isoform 3 | 1 | 0 | 0 | 1 |
| DNA polymerase kappa isoform 1 | 1 | 0 | 0 | 1 |
| Solute carrier family 22 member 20 | 0 | 1 | 0 | 1 |
| Solute carrier family 22 member 6 | 0 | 1 | 0 | 1 |
| Rap guanine nucleotide exchange factor 4 | 1 | 0 | 0 | 1 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | 1 | 0 | 0 | 1 |
| Microtubule-associated protein tau | 1 | 0 | 0 | 1 |
| glucocorticoid receptor [Homo sapiens] | 1 | 0 | 0 | 1 |
| vitamin D3 receptor isoform VDRA | 1 | 0 | 0 | 1 |
| peripheral myelin protein 22 | 1 | 0 | 0 | 1 |
| Bile salt export pump | 0 | 1 | 0 | 1 |
| Cystathionine gamma-lyase | 0 | 1 | 0 | 1 |
| Succinyl-diaminopimelate desuccinylase | 0 | 1 | 0 | 1 |
| Chain A, Immunoglobulin | 0 | 0 | 1 | 1 |
| Chain B, Immunoglobulin | 0 | 0 | 1 | 1 |
| Muscarinic acetylcholine receptor M1 | 0 | 0 | 1 | 1 |
| Muscarinic acetylcholine receptor M3 | 0 | 0 | 1 | 1 |
| Muscarinic acetylcholine receptor M4 | 0 | 0 | 1 | 1 |
| Muscarinic acetylcholine receptor M5 | 0 | 0 | 1 | 1 |
| Muscarinic acetylcholine receptor M2 | 0 | 0 | 1 | 1 |
| Muscarinic acetylcholine receptor M1 | 0 | 0 | 1 | 2 |
| Cytochrome P450 2B6 | 0 | 1 | 0 | 1 |
| Sodium-dependent serotonin transporter | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M4 | 0 | 0 | 1 | 2 |
| Delta-type opioid receptor | 0 | 0 | 0 | 1 |
| Kappa-type opioid receptor | 0 | 0 | 0 | 1 |
| Lysosomal Pro-X carboxypeptidase | 0 | 1 | 0 | 1 |
| Mu-type opioid receptor | 0 | 0 | 0 | 1 |
| Cholinesterase | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M5 | 0 | 0 | 1 | 2 |
| Sigma non-opioid intracellular receptor 1 | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M3 | 0 | 0 | 1 | 2 |
| Muscarinic acetylcholine receptor M2 | 0 | 0 | 1 | 2 |
| Sigma non-opioid intracellular receptor 1 | 0 | 2 | 0 | 2 |
| Chain A, Ferritin light chain | 0 | 0 | 1 | 1 |
| Chain A, Ferritin light chain | 0 | 0 | 1 | 1 |
| Chain A, Ferritin light chain | 0 | 0 | 1 | 1 |
| Chain A, Ferritin light chain | 0 | 0 | 1 | 1 |
| Chain A, Ferritin light chain | 0 | 0 | 1 | 1 |
| Chain A, Ferritin light chain | 0 | 0 | 1 | 1 |
| Chain A, Ferritin light chain | 0 | 0 | 1 | 1 |
| USP1 protein, partial | 1 | 0 | 0 | 1 |
| caspase 7, apoptosis-related cysteine protease | 1 | 0 | 0 | 1 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 1 | 0 | 0 | 1 |
| thyroid stimulating hormone receptor | 1 | 0 | 0 | 1 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 1 | 0 | 0 | 1 |
| farnesoid X nuclear receptor | 1 | 0 | 0 | 1 |
| pregnane X nuclear receptor | 1 | 0 | 0 | 1 |
| G | 1 | 0 | 0 | 1 |
| caspase-3 | 1 | 0 | 0 | 1 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 1 | 0 | 0 | 1 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | 1 | 0 | 0 | 1 |
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform 2 | 1 | 0 | 0 | 1 |
| heat shock protein beta-1 | 1 | 0 | 0 | 1 |
| DNA polymerase iota isoform a (long) | 1 | 0 | 0 | 1 |
| muscarinic acetylcholine receptor M1 | 1 | 0 | 0 | 1 |
| Fatty-acid amide hydrolase 1 | 0 | 1 | 0 | 1 |
| UDP-glucuronosyltransferase 1A9 | 0 | 0 | 0 | 1 |
| 5-hydroxytryptamine receptor 4 | 0 | 2 | 0 | 2 |
| Interferon beta | 1 | 0 | 0 | 1 |
| HLA class I histocompatibility antigen, B alpha chain | 1 | 0 | 0 | 1 |
| Aldo-keto reductase family 1 member B1 | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 0 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 0 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 0 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 0 | 0 | 0 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 0 | 1 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 0 | 1 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 0 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 0 | 0 | 0 | 1 |
| Prostaglandin G/H synthase 1 | 0 | 1 | 0 | 1 |
| Sodium-dependent noradrenaline transporter | 0 | 2 | 0 | 2 |
| Sodium- and chloride-dependent GABA transporter 1 | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 2C | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 0 | 1 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 0 | 0 | 1 | 1 |
| Sodium- and chloride-dependent GABA transporter 2 | 0 | 1 | 0 | 1 |
| Sodium- and chloride-dependent GABA transporter 3 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 0 | 0 | 1 | 1 |
| 5-hydroxytryptamine receptor 2B | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 0 | 0 | 1 | 1 |
| Sodium- and chloride-dependent betaine transporter | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 0 | 0 | 1 | 1 |
| Inositol hexakisphosphate kinase 1 | 1 | 0 | 0 | 1 |
| UDP-glucuronosyltransferase 1A8 | 0 | 0 | 0 | 1 |
| cytochrome P450 2C9, partial | 1 | 0 | 0 | 1 |
| Replicase polyprotein 1ab | 0 | 1 | 0 | 1 |
| Replicase polyprotein 1ab | 0 | 1 | 0 | 1 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |