Page last updated: 2024-09-27

Landau-Kleffner Syndrome

A syndrome characterized by the onset of isolated language dysfunction in otherwise normal children (age of onset 4-7 years) and epileptiform discharges on ELECTROENCEPHALOGRAPHY. Seizures, including atypical absence (EPILEPSY, ABSENCE), complex partial (EPILEPSY, COMPLEX PARTIAL), and other types may occur. The electroencephalographic abnormalities and seizures tend to resolve by puberty. The language disorder may also resolve although some individuals are left with severe language dysfunction, including APHASIA and auditory AGNOSIA. (From Menkes, Textbook of Child Neurology, 5th ed, pp749-50; J Child Neurol 1997 Nov;12(8):489-495).

Synonyms(1)

Synonym
Landau-Kleffner Syndrome

Research

Studies (64)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's14 (21.88)12.5806
2000's32 (50.00)18.1394
2010's17 (26.56)28.8240
2020's1 (1.56)9.53
DrugIndicatedRelationship StrengthStudiesTrials
gamma-aminobutyric acid0low10
nitrous oxide0low10
phenytoin0low20
amantadine0low10
carbamazepine0low50
chlorpromazine0low10
clobazam0low10
clonazepam0low30
valproic acid0low160
ethosuximide0low20
flunitrazepam0low10
haloperidol0low10
lamotrigine0low10
methylphenidate0low10
piracetam0low30
promethazine0low10
sevoflurane0low10
sulthiame0low50
vigabatrin0low10
prednisolone0medium51
prednisone0medium51
methylprednisolone0low40
methohexital0low20
fluorodeoxyglucose f180low30
4-aminopiperidine0low10
retinol0low10
myelin basic protein0low10
levetiracetam0low30
stiripentol0low10
technetium tc 99m exametazime0low40
neuropeptide y0low10
piperidines0low10

Protein Targets (604)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, TYROSYL-DNA PHOSPHODIESTERASE4004
Chain A, CARBONIC ANHYDRASE II0011
Chain A, CARBONIC ANHYDRASE II0011
Chain A, CARBONIC ANHYDRASE II0011
Chain A, Carbonic Anhydrase Ii0011
Chain A, Carbonic Anhydrase Ii0011
Chain A, Beta-lactamase3003
Chain A, Endochitinase0101
Chain A, Endochitinase0101
Chain A, Endochitinase0101
Chain A, Class Iii Chitinase Chia10101
Chain A, Carbonic anhydrase 130101
Chain A, Carbonic anhydrase II0101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase0101
Chain B, Carbonic anhydrase0101
Chain A, Carbonic anhydrase 20101
Carbonic anhydrase 0001
Carbonic anhydrase 0202
thioredoxin reductase120012
GALC protein2002
GLI family zinc finger 3110011
nuclear receptor subfamily 1, group I, member 3100010
cytochrome P450 family 3 subfamily A polypeptide 47007
glucocorticoid receptor [Homo sapiens]110011
retinoic acid nuclear receptor alpha variant 1110011
retinoid X nuclear receptor alpha4004
estrogen-related nuclear receptor alpha140014
Carbonic anhydrase 0202
Carbonic anhydrase 0202
arylsulfatase A7007
Carbonic anhydrase0202
euchromatic histone-lysine N-methyltransferase 2130013
Bloom syndrome protein isoform 16006
thyroid hormone receptor beta isoform a5005
nuclear factor erythroid 2-related factor 2 isoform 18008
geminin100010
peripheral myelin protein 227007
survival motor neuron protein isoform d2002
muscleblind-like protein 1 isoform 12002
Gamma-aminobutyric acid receptor subunit pi38112
ATP-binding cassette sub-family C member 3013013
Multidrug resistance-associated protein 4013013
Carbonic anhydrase0101
Solute carrier family 22 member 60101
Carbonic anhydrase 120317
Prolyl endopeptidase0101
Carbonic anhydrase-related protein 110102
Bile salt export pump015015
Glycogen phosphorylase, muscle form0101
Renin0202
Carbonic anhydrase 10319
Carbonic anhydrase 20318
Carbonic anhydrase 20202
Cytochrome P450 1A20112
Carbonic anhydrase 30316
Cathepsin B0101
Cytochrome P450 3A40203
Steryl-sulfatase0101
5-hydroxytryptamine receptor 2C0404
Polyunsaturated fatty acid 5-lipoxygenase0101
Cytochrome P450 2C80101
Cytochrome P450 2D60213
Cytochrome P450 2A60202
Cytochrome P450 2C9 0606
5-hydroxytryptamine receptor 2A0404
Androgen receptor0404
Gamma-aminobutyric acid receptor subunit beta-138112
Translocator protein0214
Gamma-aminobutyric acid receptor subunit delta38112
Gamma-aminobutyric acid receptor subunit gamma-238213
Gamma-aminobutyric acid receptor subunit alpha-538112
Gamma-aminobutyric acid receptor subunit alpha-338112
Cannabinoid receptor 10101
Arachidonate 5-lipoxygenase-activating protein0101
Cytochrome P450 2B60112
Carbonic anhydrase 40316
Carbonic anhydrase 60316
Gamma-aminobutyric acid receptor subunit gamma-138112
Gamma-aminobutyric acid receptor subunit alpha-238112
Carbonic anhydrase 5A, mitochondrial0101
Adenosine receptor A10202
Serum paraoxonase/arylesterase 10101
Dipeptidyl peptidase 40001
Gamma-aminobutyric acid receptor subunit alpha-438112
Gamma-aminobutyric acid receptor subunit gamma-338112
Endochitinase0101
Gamma-aminobutyric acid receptor subunit alpha-638112
Adenosine receptor A2a0101
5-hydroxytryptamine receptor 2B0404
Sodium-dependent serotonin transporter0202
Delta-type opioid receptor0202
Cytochrome P450 2C190101
Delta-type opioid receptor0303
Mu-type opioid receptor0303
Carbonic anhydrase 5A, mitochondrial0317
Carbonic anhydrase0101
Kappa-type opioid receptor0202
Carbonic anhydrase 70316
Carbonic anhydrase0101
D(1A) dopamine receptor3205
Corticosteroid 11-beta-dehydrogenase isozyme 10101
Carbonic anhydrase0202
D(2) dopamine receptor0506
Gamma-aminobutyric acid receptor subunit alpha-138213
Gamma-aminobutyric acid receptor subunit beta-338112
Gamma-aminobutyric acid receptor subunit beta-238213
Cholinesterase0101
Carbonic anhydrase 0101
Mu-type opioid receptor0202
Fatty-acid amide hydrolase 10101
Beta-carbonic anhydrase 10202
Carbonic anhydrase 20202
Glutamate receptor ionotropic, NMDA 2B0404
Squalene synthase0101
Neuronal acetylcholine receptor subunit alpha-70202
Carbonic anhydrase 90317
Carbonic anhydrase0101
Carbonic anhydrase, alpha family 0202
Carbonic anhydrase 0101
Carbonic anhydrase 30101
Carbonic anhydrase0102
Carbonic anhydrase0203
Carbonic anhydrase 0202
Sigma intracellular receptor 20202
Delta carbonic anhydrase0202
Sigma non-opioid intracellular receptor 10303
Renin0101
Carbonic anhydrase 0101
Endochitinase A10101
Multidrug resistance-associated protein 10101
Carbonic anhydrase 130315
GABA theta subunit38112
Canalicular multispecific organic anion transporter 1012012
Carbonic anhydrase 40202
Carbonic anhydrase 150203
Acidic mammalian chitinase0101
Carbonic anhydrase 130204
Carbonic anhydrase 70101
Gamma-aminobutyric acid receptor subunit epsilon38112
Carbonic anhydrase 0101
Carbonic anhydrase 140317
Carbonic anhydrase 0101
Carbonic anhydrase 2, isoform A 0101
Carbonic anhydrase 5B, mitochondrial0317
acetylcholinesterase8008
RAR-related orphan receptor gamma8008
NFKB1 protein, partial3003
AR protein130013
signal transducer and activator of transcription 6, interleukin-4 induced1001
thyroid stimulating hormone receptor6006
regulator of G-protein signaling 45005
EWS/FLI fusion protein5005
estrogen nuclear receptor alpha120012
putative alpha-glucosidase1001
thyroid hormone receptor beta isoform 27007
heat shock protein beta-13003
histone acetyltransferase KAT2A isoform 14004
lamin isoform A-delta106006
Solute carrier family 22 member 20102
Solute carrier family 22 member 1 0304
Glutamate receptor ionotropic, NMDA 2D0202
Glutamate receptor ionotropic, NMDA 3B0202
Matrix protein 20112
Matrix protein 20123
Glutamate receptor ionotropic, NMDA 1 0303
Spike glycoprotein72211
Glutamate receptor ionotropic, NMDA 2A 0303
Glutamate receptor ionotropic, NMDA 2C0303
Glutamate receptor ionotropic, NMDA 10202
Glutamate receptor ionotropic, NMDA 2A0202
Glutamate receptor ionotropic, NMDA 2B0202
Glutamate receptor ionotropic, NMDA 2C0202
Glutamate receptor ionotropic, NMDA 2D0303
Solute carrier family 22 member 10101
Glutamate receptor ionotropic, NMDA 3A0202
Glutamate receptor ionotropic, NMDA 3B0303
Multidrug and toxin extrusion protein 10101
Solute carrier family 22 member 20101
Glutamate receptor ionotropic, NMDA 3A0303
ATP-dependent phosphofructokinase6006
USP1 protein, partial4004
TDP1 protein100010
pregnane X nuclear receptor110011
IDH13003
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a9009
nuclear factor erythroid 2-related factor 2 isoform 25005
mitogen-activated protein kinase 14004
Vpr1001
Bile salt export pump0303
Albumin0044
Major prion protein0044
Cellular tumor antigen p539009
Sodium channel protein type 1 subunit alpha0202
Sodium channel protein type 2 subunit alpha0303
Sodium channel protein type 3 subunit alpha0202
UDP-glucuronosyltransferase 2B70205
Sodium channel protein type 4 subunit alpha0508
Cytochrome P450 2J20404
Potassium voltage-gated channel subfamily H member 20707
Sodium channel protein type 9 subunit alpha0606
Frizzled-80011
P2X purinoceptor 40101
Proteasome subunit beta type-110001
phosphopantetheinyl transferase3003
ATAD5 protein, partial4004
Fumarate hydratase2002
Microtubule-associated protein tau3003
Thrombopoietin2002
Smad31001
caspase 7, apoptosis-related cysteine protease2002
estrogen receptor 2 (ER beta)6006
progesterone receptor8008
NADPH oxidase 10101
farnesoid X nuclear receptor4004
G5005
cytochrome P450 2D65005
polyprotein2002
67.9K protein1001
peroxisome proliferator-activated receptor delta3003
peroxisome proliferator activated receptor gamma5005
vitamin D (1,25- dihydroxyvitamin D3) receptor6006
Snq2p0002
caspase-32002
Adenylate cyclase type 1 0303
thyroid stimulating hormone receptor3003
v-jun sarcoma virus 17 oncogene homolog (avian)5005
Histone H2A.x1001
Caspase-71001
Spike glycoprotein0224
Replicase polyprotein 1ab0224
cytochrome P450 2D6 isoform 13003
cellular tumor antigen p53 isoform a1001
D(1A) dopamine receptor6006
vitamin D3 receptor isoform VDRA4004
chromobox protein homolog 15005
potassium voltage-gated channel subfamily H member 2 isoform d6006
caspase-31001
histone deacetylase 9 isoform 31001
atrial natriuretic peptide receptor 2 precursor1001
ras-related protein Rab-9A1001
serine/threonine-protein kinase mTOR isoform 13003
DNA polymerase kappa isoform 11001
cytochrome P450 3A4 isoform 13003
M-phase phosphoprotein 83003
muscarinic acetylcholine receptor M14004
lethal factor (plasmid)2002
Proteasome subunit alpha type-70001
Polyunsaturated fatty acid lipoxygenase ALOX15B2002
Transmembrane protease serine 20224
Transient receptor potential cation channel subfamily V member 10202
Voltage-dependent L-type calcium channel subunit alpha-1F0404
5-hydroxytryptamine receptor 40606
Potassium channel subfamily K member 20202
Epidermal growth factor receptor0101
Interferon beta6006
HLA class I histocompatibility antigen, B alpha chain 5005
Albumin0023
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10101
Receptor tyrosine-protein kinase erbB-20101
Major prion protein0011
Integrin beta-31001
Tyrosine-protein kinase Fyn0101
Procathepsin L0224
Aldo-keto reductase family 1 member B10707
Muscarinic acetylcholine receptor M20505
Muscarinic acetylcholine receptor M40505
ATP-dependent translocase ABCB10306
Muscarinic acetylcholine receptor M10303
Muscarinic acetylcholine receptor M30303
Muscarinic acetylcholine receptor M40303
Integrin alpha-IIb1001
5-hydroxytryptamine receptor 1A0303
Muscarinic acetylcholine receptor M50303
Muscarinic acetylcholine receptor M50606
Alpha-2A adrenergic receptor0606
Replicase polyprotein 1a0224
Replicase polyprotein 1ab0224
Replicase polyprotein 1ab0224
Cys-loop ligand-gated ion channel0101
Calmodulin-10314
Replicase polyprotein 1ab0224
Muscarinic acetylcholine receptor M20303
Muscarinic acetylcholine receptor M10606
Polyunsaturated fatty acid lipoxygenase ALOX150101
Angiotensin-converting enzyme0303
D(2) dopamine receptor06110
Alpha-1B adrenergic receptor0404
Sphingomyelin phosphodiesterase0101
Alpha-2B adrenergic receptor0606
Alpha-2C adrenergic receptor0606
D0404
D(3) dopamine receptor0404
5-hydroxytryptamine receptor 1A09110
Alpha-2B adrenergic receptor0303
D(2) dopamine receptor0303
Muscarinic acetylcholine receptor M30505
Proteasome subunit beta type-10001
Substance-K receptor0202
D(1A) dopamine receptor0608
D(4) dopamine receptor0418
D(1B) dopamine receptor0305
Adenylate cyclase type 30303
Alpha-2C adrenergic receptor0303
UDP-glucuronosyltransferase 1A40002
Alpha-2A adrenergic receptor0303
Alpha-1D adrenergic receptor0404
Sodium-dependent noradrenaline transporter 0808
Sodium-dependent dopamine transporter0404
Histamine H2 receptor0606
Alpha-1D adrenergic receptor0606
D(1B) dopamine receptor0404
Proteasome subunit alpha type-10001
Proteasome subunit alpha type-20001
Proteasome subunit alpha type-30001
Proteasome subunit alpha type-40001
Adenylate cyclase type 20303
Adenylate cyclase type 40303
Proteasome subunit beta type-80001
Proteasome subunit beta type-90001
Proteasome subunit alpha type-50001
Proteasome subunit beta type-40001
Proteasome subunit beta type-60001
Proteasome subunit beta type-50001
5-hydroxytryptamine receptor 2A0606
5-hydroxytryptamine receptor 2C0606
5-hydroxytryptamine receptor 1B0505
Trypanothione reductase0404
D(4) dopamine receptor0404
Histamine H1 receptor0112
Sodium-dependent serotonin transporter0808
Melanocortin receptor 40202
5-hydroxytryptamine receptor 7 0202
Melanocortin receptor 50202
Pleiotropic ABC efflux transporter of multiple drugs0204
5-hydroxytryptamine receptor 70202
Histamine H1 receptor0606
Mu-type opioid receptor0415
D(3) dopamine receptor06110
Sodium channel protein type 1 subunit alpha0303
Adenylate cyclase type 80303
Proteasome subunit beta type-100001
Delta-type opioid receptor0202
Kappa-type opioid receptor0202
5-hydroxytryptamine receptor 2B0606
Melanocortin receptor 30202
Alpha-1A adrenergic receptor0404
Histamine H2 receptor3004
Proteasome subunit beta type-30001
Proteasome subunit beta type-20001
5-hydroxytryptamine receptor 60505
5-hydroxytryptamine receptor 70303
Gastrin/cholecystokinin type B receptor0202
Proteasome subunit alpha type-60012
Calmodulin 0123
Aldehyde oxidase 10101
Sodium channel protein type 7 subunit alpha0202
Voltage-dependent L-type calcium channel subunit alpha-1D 0404
Sodium-dependent dopamine transporter 0404
Adenylate cyclase type 60303
Adenylate cyclase type 50303
Aldehyde oxidase0202
Voltage-dependent L-type calcium channel subunit alpha-1S0404
Voltage-dependent L-type calcium channel subunit alpha-1C0505
Sodium channel protein type 5 subunit alpha0404
Nuclear receptor subfamily 3 group C member 3 0202
Adenylyl cyclase 7 0303
Proteasome subunit alpha-type 80001
Inositol hexakisphosphate kinase 15005
D0202
Sodium channel protein type 2 subunit alpha0404
Proteasome subunit beta type-70001
Ataxin-27007
Sigma non-opioid intracellular receptor 10606
Angiotensin-converting enzyme 2 0224
Sodium channel protein type 3 subunit alpha0404
Sodium channel protein type 11 subunit alpha0202
Sodium channel protein type 8 subunit alpha0202
Histamine H3 receptor0101
Sodium channel protein type 10 subunit alpha0303
cytochrome P450 2C9, partial5005
nuclear receptor subfamily 1, group I, member 23003
Gamma-aminobutyric acid receptor subunit pi0707
Gamma-aminobutyric acid receptor subunit delta0707
Gamma-aminobutyric acid receptor subunit alpha-10303
Gamma-aminobutyric acid receptor subunit beta-10303
Neuronal acetylcholine receptor subunit alpha-40202
Gamma-aminobutyric acid receptor subunit alpha-20303
Gamma-aminobutyric acid receptor subunit alpha-30303
Neuronal acetylcholine receptor subunit beta-20202
Gamma-aminobutyric acid receptor subunit alpha-108614
Gamma-aminobutyric acid receptor subunit beta-10718
Gamma-aminobutyric acid receptor subunit gamma-208412
Gamma-aminobutyric acid receptor subunit alpha-40303
Gamma-aminobutyric acid receptor subunit gamma-20303
Gamma-aminobutyric acid receptor subunit beta-308210
Translocator protein0202
Translocator protein0303
Cholecystokinin receptor type A0303
Gastrin/cholecystokinin type B receptor0303
Gamma-aminobutyric acid receptor subunit alpha-508412
Gamma-aminobutyric acid receptor subunit alpha-308210
Gamma-aminobutyric acid receptor subunit alpha-208210
Gamma-aminobutyric acid receptor subunit beta-208412
Gamma-aminobutyric acid receptor subunit alpha-40718
Gamma-aminobutyric acid receptor subunit epsilon0707
Gamma-aminobutyric acid receptor subunit alpha-60819
Gamma-aminobutyric acid receptor subunit gamma-10707
Gamma-aminobutyric acid receptor subunit gamma-30707
Gamma-aminobutyric acid receptor subunit theta0707
Gamma-aminobutyric acid 0213
glp-1 receptor, partial3003
Voltage-dependent calcium channel gamma-2 subunit3003
Fatty acid-binding protein, liver0202
Alpha-1-acid glycoprotein 10001
Gamma-aminobutyric acid receptor subunit alpha-60213
Glutamate receptor 23003
Gamma-aminobutyric acid receptor subunit gamma-20213
Gamma-aminobutyric acid receptor subunit delta0213
Gamma-aminobutyric acid receptor subunit alpha-20213
Gamma-aminobutyric acid receptor subunit alpha-30213
Gamma-aminobutyric acid receptor subunit gamma-30213
Gamma-aminobutyric acid receptor subunit beta-10213
Gamma-aminobutyric acid receptor subunit alpha-10213
Gamma-aminobutyric acid receptor subunit beta-30213
Gamma-aminobutyric acid receptor subunit alpha-50213
Gamma-aminobutyric acid receptor subunit pi0213
Sphingosine-1-phosphate lyase 10101
ATPase family AAA domain-containing protein 55005
Gamma-aminobutyric acid receptor subunit alpha-40213
Gamma-aminobutyric acid receptor subunit theta0213
Gamma-aminobutyric acid receptor subunit gamma-10213
hypoxia-inducible factor 1 alpha subunit3003
GLS protein4004
nuclear receptor ROR-gamma isoform 15005
neuropeptide S receptor isoform A2002
Voltage-dependent T-type calcium channel subunit alpha-1I0101
Chain A, Ferritin light chain1001
Gamma-aminobutyric acid receptor subunit rho-30011
Hsf1 protein0023
bromodomain adjacent to zinc finger domain 2B2002
transcriptional regulator ERG isoform 32002
histone-lysine N-methyltransferase 2A isoform 2 precursor1001
Histone deacetylase 30303
Gamma-aminobutyric acid type B receptor subunit 20112
Gamma-aminobutyric acid type B receptor subunit 20101
Sodium- and chloride-dependent GABA transporter 10101
Gamma-aminobutyric acid receptor subunit rho-10022
Gamma-aminobutyric acid receptor subunit rho-20011
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent taurine transporter0101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent betaine transporter0101
Sodium- and chloride-dependent betaine transporter0101
Sodium- and chloride-dependent GABA transporter 30101
Histone deacetylase 40303
4-aminobutyrate aminotransferase, mitochondrial0102
4-aminobutyrate aminotransferase, mitochondrial0102
TAR DNA-binding protein 432002
Histone deacetylase 10303
Sterol O-acyltransferase 10011
Proton-coupled amino acid transporter 10101
Histone deacetylase 70303
Histone deacetylase 20303
Polyamine deacetylase HDAC100303
Histone deacetylase 11 0303
Histone deacetylase 80303
Platelet glycoprotein VI0011
Sodium- and chloride-dependent GABA transporter 20101
Histone deacetylase 60303
Gamma-aminobutyric acid type B receptor subunit 10112
Histone deacetylase 90303
Histone deacetylase 50303
Gamma-aminobutyric acid type B receptor subunit 10101
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE2002
15-lipoxygenase, partial2002
nonstructural protein 12002
glucocerebrosidase2002
peripheral myelin protein 22 isoform 13003
cytochrome P450 2C9 precursor2002
transient receptor potential cation channel subfamily V member 11001
Cocaine esterase0202
Voltage-dependent L-type calcium channel subunit alpha-1C0202
UDP-glucuronosyltransferase 1A90103
Vitamin D-binding protein0101
HLA class I histocompatibility antigen, A alpha chain 0011
Integrin beta-10101
Beta-2 adrenergic receptor0202
Integrin alpha-40101
Carbonyl reductase [NADPH] 10001
Beta-1 adrenergic receptor0101
5-hydroxytryptamine receptor 3A0101
Beta-3 adrenergic receptor0101
5-hydroxytryptamine receptor 1D0101
5-hydroxytryptamine receptor 1F0101
Histamine H1 receptor0202
C-8 sterol isomerase0101
5-hydroxytryptamine receptor 2C 0101
Kappa-type opioid receptor0101
Alpha-1A adrenergic receptor0101
5-hydroxytryptamine receptor 2A0101
Alpha-1B adrenergic receptor0101
5-hydroxytryptamine receptor 2A0101
D(2) dopamine receptor0101
D(3) dopamine receptor0101
AP-2 complex subunit sigma0101
N-acetyltransferase Eis0202
5-hydroxytryptamine receptor 2B0101
5-hydroxytryptamine receptor 40101
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0101
Calcitonin gene-related peptide type 1 receptor0101
Genome polyprotein 0202
Sigma intracellular receptor 20101
Zinc finger protein 6640101
Vesicular acetylcholine transporter0101
Transporter0101
Cholecystokinin receptor type A0101
Protease 0202
Transient receptor potential cation channel subfamily V member 40101
Sigma non-opioid intracellular receptor 10303
Transient receptor potential cation channel subfamily V member 20101
Dihydrofolate reductase0202
Potassium voltage-gated channel subfamily E member 10101
Potassium voltage-gated channel subfamily KQT member 10101
chaperonin-containing TCP-1 beta subunit homolog1001
flap endonuclease 12002
Synaptic vesicle glycoprotein 2A0202
PPM1D protein1001
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)2002
Nuclear receptor subfamily 1 group I member 20011
Glucocorticoid receptor06213
Glycine receptor subunit alpha-10606
Glycine receptor subunit beta0606
Glycine receptor subunit alpha-20606
Glycine receptor subunit alpha-30606
Nuclear receptor subfamily 1 group I member 20011
Neuropeptide Y receptor type 10202
Neuropeptide Y receptor type 20202
Chain A, Putative fructose-1,6-bisphosphate aldolase1001
endonuclease IV2002
aldehyde dehydrogenase 1 family, member A14004
atrial natriuretic peptide receptor 1 precursor1001
parathyroid hormone/parathyroid hormone-related peptide receptor precursor2002
Dihydrofolate reductase 0101
Aldo-keto reductase family 1 member B10101
Inositol monophosphatase 12002
Guanine nucleotide-binding protein G1001
luciferase0001
aryl hydrocarbon receptor2002
Estrogen receptor0202
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Corticosteroid-binding globulin0101
Mineralocorticoid receptor 0213
Androgen receptor0202
Glutamine synthetase0011
Prostaglandin G/H synthase 20101
Nociceptin receptor0011
Estrogen receptor beta0202
Chain A, HADH2 protein1001
Chain B, HADH2 protein1001
pregnane X receptor3003
thioredoxin glutathione reductase1001
Nuclear receptor ROR-gamma3003
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a2002
huntingtin isoform 21001
Voltage-dependent N-type calcium channel subunit alpha-1B0101
Chloroquine resistance transporter0101
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR0011
Chain A, Cruzipain1001
interleukin 81001
SMAD family member 21001
SMAD family member 31001
ubiquitin carboxyl-terminal hydrolase 2 isoform a1001
DNA polymerase iota isoform a (long)1001
Retinol-binding protein 40011
Beta-lactoglobulin0011
Amyloid-beta precursor protein0101
Alpha-synuclein0101
Disintegrin and metalloproteinase domain-containing protein 171001
Luciferase2002
Chain A, Carbonic anhydrase 20101
Tissue factor0101
Aldo-keto reductase family 1 member A10101
UDP-glucuronosyltransferase 1-60001
Liver carboxylesterase 10101
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member B70101
NAD-dependent protein deacylase sirtuin-5, mitochondrial0101
4-aminobutyrate aminotransferase, mitochondrial0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]