Page last updated: 2024-09-28

Keratoconjunctivitis Sicca

Drying and inflammation of the conjunctiva as a result of insufficient lacrimal secretion. When found in association with XEROSTOMIA and polyarthritis, it is called SJOGREN'S SYNDROME.

Synonyms(1)

Synonym
Keratoconjunctivitis Sicca

Research Excerpts

Overview

ExcerptReference
"Keratoconjunctivitis sicca is a commonly encountered disease with decreased lacrimal gland activity."( Hu, FR; Ko, LS; Lin, LL; Wang, TH, 1989)
"Keratoconjunctivitis sicca is a common ocular surface disease that develops in patients with aqueous tear deficiency."( Pflugfelder, SC, 1998)
"Keratoconjunctivitis sicca is a common eye condition characterized by itchiness, redness, and dryness due to a lack of tear production or abnormalities in the tear film."( Katsev, D; Kerney, D; Trattler, W, 2006)
"Dry eye disease, or keratoconjunctivitis sicca, is a multifactorial syndrome with altered tear film homeostasis leading to ocular irritations."( Boldin, I; Haslwanter, T; Horwath-Winter, J; Rabensteiner, DF; Reitsamer, H; Ring, MH; Schrödl, F, 2015)
"Severe keratoconjunctivitis sicca is common in patients with chronic GVH disease."( Delcampe, A; Doan, S; Duncombe, A; Gabison, E; Gueudry, J; Muraine, M; Rossi, P, 2015)
"Keratoconjunctivitis sicca is one of the most common ocular diseases and is associated with a considerable decrease in the quality of life."( Jacobi, C; Paulsen, F; Schneider, E, 2020)

Actions

ExcerptReference
"Keratoconjunctivitis sicca affects 5% to 33% of the population and is often accompanied by symptoms such as burning and dryness."( Bacharach, J; Darby, C; Devries, DK; Kabat, A; Karpecki, P; Luchs, J; Malhotra, R; Ogundele, A; Schechter, BA; Shen Lee, B; Shettle, L; Smyth-Medina, R, 2019)

Research

Studies (318)

TimeframeStudies, This Condition (%)All Conditions %
pre-199072 (22.64)23.3326
1990's80 (25.16)12.5806
2000's81 (25.47)18.1394
2010's71 (22.33)28.8240
2020's14 (4.40)9.53
DrugIndicatedRelationship StrengthStudiesTrials
citric acid, anhydrous0low10
chlorine0low10
glycerol0medium11
iodine0low10
nitrates0low10
propylene glycol0medium11
urea0low10
4-diphenylacetoxy-1,1-dimethylpiperidinium0low10
acetaminophen0low10
aspirin0low10
atenolol0low10
azathioprine0low20
bromhexine0low50
cetyl alcohol0medium11
diclofenac0low10
diphenhydramine0low10
epinastine0low10
erythrosine0low90
etodolac0low30
fluorouracil0low10
gentamicin0low10
guaifenesin0low90
hydroxychloroquine0medium41
1-methyl-3-isobutylxanthine0low20
2-propanol0low20
ketamine0low10
mesalamine0low20
miconazole0low10
neostigmine0low10
benoxinate0low20
phenolsulfonphthalein0low10
pirenzepine0low10
procaine0low20
proxymetacaine0low10
opc 127590low10
sulfadiazine0low20
sodium iodide0low10
sulfamethoxazole0low10
sulfasalazine0low10
trimethoprim0low20
tropicamide0low10
xylazine0low10
prednisolone0medium21
thyroxine0low10
carbachol0low20
prednisone0low40
pilocarpine0medium81
alanine0low10
chloramphenicol0low30
sucrose0medium11
aminopyrine0low10
bromodeoxyuridine0low10
carbostyril0low20
lactose0low10
phenylalanine0low30
trichloroacetic acid0low10
methylprednisolone0low30
propoxycaine0low10
n-vinyl-2-pyrrolidinone0medium32
quinuclidines0medium21
thiophenes0medium21
azacitidine0low10
fluorometholone0low20
glycerylphosphorylcholine0low10
erythromycin0low10
diphenoxylate0low10
deoxycytidine0low10
fluorescein0medium336
methylprednisolone hemisuccinate0medium11
trolamine salicylate0low60
ursodeoxycholic acid0low10
colforsin0low10
fomesafen0low20
mk 4580low10
capecitabine0low10
sulfadiazine, trimethoprim drug combination0low10
enrofloxacin0low10
6-carboxyfluorescein0low40
acid green 500low10
glucuronic acid0low10
florfenicol0low10
9-o-acetyl-n-acetylneuraminic acid0low10
methotrexate0low30
diquafosol0low30
technetium tc 99m pentetate0low20
atropine0medium21
cortisone0low20
trimethoprim, sulfamethoxazole drug combination0low20
povidone-iodine0medium21
glycogen0low30
inositol 3-phosphate0low60
loteprednol etabonate0medium21
tretinoin0medium31
retinol0medium81
tacrolimus0medium74
eicosapentaenoic acid0medium11
mycophenolic acid0medium11
zithromax0medium11
riboflavin0low10
dipyrone0low10
bromochloroacetic acid0low20
amygdalin0low10
thiouracil0low10
capsaicin0low20
terbinafine0low10
lithium0low10
dinoprostone0low10
linoleic acid0medium11
gamma-linolenic acid0medium22
sdz psc 8330low10
etretinate0medium11
olopatadine hydrochloride0low10
phenylephrine hydrochloride0low20
sirolimus0medium11
lead0low10
thallium0low10
naltrexone0medium11
cysteine0medium11
phosphorus0low10
cbs 211 a0low10
mocetinostat0low10
eledoisin0medium11
ino-88750low10
sar 11180low30
scopolamine hydrobromide0low30
cellulose0medium33
sodium pertechnetate tc 99m0low70
glycolipids0low10
piperidines0low10
interleukin-80low10
oclacitinib0medium11
methylcellulose0medium73
vasoactive intestinal peptide0low20
chondroitin0medium11
piroxicam0low10
epidermal growth factor0low50
transforming growth factor beta0low30
moxidectin0low10
cyclosporine0medium6019
lactoferrin0medium142
orabase0medium11
muramidase0low130
chondroitin sulfates0medium11
acyclovir0low10
eye0medium272
concanavalin a0low10

Protein Targets (1,281)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, High-affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Chain A, Phosphodiesterase 9A0101
Chain A, JmjC domain-containing histone demethylation protein 3A4004
Chain A, Class I phosphodiesterase PDEB10101
Chain A, High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A0101
Chain A, cGMP-dependent 3',5'-cyclic phosphodiesterase0101
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase catalytic domain, Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha chimera0101
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase catalytic domain, Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha chimera0101
Chain A, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A0101
Chain A, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A0101
glp-1 receptor, partial110011
thyroid stimulating hormone receptor180018
estrogen-related nuclear receptor alpha390039
Phosphodiesterase 0101
mitogen-activated protein kinase 15005
geminin390039
cytochrome P450 3A4 isoform 1190019
histone acetyltransferase KAT2A isoform 1150015
cGMP-dependent 3',5'-cyclic phosphodiesterase0101
Gamma-aminobutyric acid receptor subunit pi190120
Monocarboxylate transporter 40101
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A0101
cGMP-specific 3',5'-cyclic phosphodiesterase0202
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A0101
Renin0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A 0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4D 0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Gamma-aminobutyric acid receptor subunit beta-1190120
Gamma-aminobutyric acid receptor subunit delta190120
Gamma-aminobutyric acid receptor subunit gamma-2190120
Gamma-aminobutyric acid receptor subunit alpha-5190120
Gamma-aminobutyric acid receptor subunit alpha-3190120
Gamma-aminobutyric acid receptor subunit gamma-1191121
Gamma-aminobutyric acid receptor subunit alpha-2190120
Adenosine receptor A10405
Gamma-aminobutyric acid receptor subunit alpha-4190120
Gamma-aminobutyric acid receptor subunit gamma-3190120
Adenosine receptor A30101
Adenosine receptor A2a0304
Adenosine receptor A2b0001
Adenosine receptor A2b0202
Gamma-aminobutyric acid receptor subunit alpha-6190120
Adenosine receptor A10417
Adenosine receptor A2a0304
Sodium-dependent serotonin transporter0202
Adenosine receptor A2a0101
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A0101
Gamma-aminobutyric acid receptor subunit alpha-1191121
Gamma-aminobutyric acid receptor subunit beta-3190120
Gamma-aminobutyric acid receptor subunit beta-2190120
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
cGMP-inhibited 3',5'-cyclic phosphodiesterase B0101
Voltage-dependent L-type calcium channel subunit alpha-1C0202
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A0202
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
cGMP-inhibited 3',5'-cyclic phosphodiesterase A0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
Phosphodiesterase 0101
GABA theta subunit190120
Phosphodiesterase 0101
Gamma-aminobutyric acid receptor subunit epsilon190120
cAMP-specific 3',5'-cyclic phosphodiesterase 7B0101
hypoxia-inducible factor 1 alpha subunit130013
RAR-related orphan receptor gamma380038
GLI family zinc finger 3370037
AR protein430043
aldehyde dehydrogenase 1 family, member A1300030
retinoic acid nuclear receptor alpha variant 1380038
retinoid X nuclear receptor alpha340034
estrogen nuclear receptor alpha610061
peroxisome proliferator-activated receptor delta230023
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a280028
activating transcription factor 6210021
v-jun sarcoma virus 17 oncogene homolog (avian)180018
Histone H2A.x140014
thyroid hormone receptor beta isoform a110011
heat shock protein beta-1110011
nuclear factor erythroid 2-related factor 2 isoform 1390039
lamin isoform A-delta10310031
Voltage-dependent calcium channel gamma-2 subunit180018
Glutamate receptor 2181019
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE180018
Chain A, HADH2 protein130013
Chain B, HADH2 protein130013
ATAD5 protein, partial140014
regulator of G-protein signaling 4140014
euchromatic histone-lysine N-methyltransferase 2350035
cytochrome P450 2D6 isoform 1100010
cytochrome P450 2C9 precursor7007
D(1A) dopamine receptor4004
serine/threonine-protein kinase mTOR isoform 15005
muscarinic acetylcholine receptor M1130013
lethal factor (plasmid)100010
Histamine H2 receptor90011
GLS protein180018
Microtubule-associated protein tau150015
Smad35005
nuclear receptor subfamily 1, group I, member 3300030
progesterone receptor220022
EWS/FLI fusion protein150015
peroxisome proliferator activated receptor gamma270027
aryl hydrocarbon receptor190019
chromobox protein homolog 1250025
thyroid hormone receptor beta isoform 2350035
peripheral myelin protein 22240024
ATP-binding cassette sub-family C member 3025025
Multidrug resistance-associated protein 4025027
Solute carrier family 22 member 60405
Carbonic anhydrase 120203
UDP-glucuronosyltransferase 1A90104
Bile salt export pump0404
Bile salt export pump045045
Cytochrome P450 2B10001
Cytochrome P450 1A10001
Carbonic anhydrase 1011013
Carbonic anhydrase 2012216
Myoglobin0101
Cytochrome P450 1A10012
Cytochrome P450 1A20315
Prostaglandin G/H synthase 10505
Carbonic anhydrase 30203
Cytochrome P450 3A4012214
Cytochrome P450 2D60618
Cytochrome P450 2C9 013216
Polyunsaturated fatty acid lipoxygenase ALOX150101
Sulfotransferase 1A1 0001
UDP-glucuronosyltransferase 1-60203
Arachidonate 5-lipoxygenase-activating protein0101
UDP-glucuronosyltransferase 1A1 0306
Carbonic anhydrase 40405
Prostaglandin G/H synthase 10808
Carbonic anhydrase 60304
Carbonic anhydrase 5A, mitochondrial0203
Prostaglandin G/H synthase 20809
Carbonic anhydrase 70203
Nuclear receptor ROR-gamma111113
Cytochrome P450 2J20909
Carbonic anhydrase 90416
Canalicular multispecific organic anion transporter 1024024
Carbonic anhydrase 150304
Carbonic anhydrase 130102
Carbonic anhydrase 140203
Carbonic anhydrase 5B, mitochondrial0203
toxin B0001
TDP1 protein370037
nuclear receptor subfamily 1, group I, member 28008
ATPase family AAA domain-containing protein 5120012
Ataxin-2130013
Chain E, Purine nucleoside phosphorylase0101
Chain A, ATP-DEPENDENT DNA HELICASE Q16006
Chain A, Ferritin light chain8008
Thymidine kinase 0101
thioredoxin reductase190019
phosphopantetheinyl transferase130013
arylsulfatase A100010
Bloom syndrome protein isoform 1150015
hemoglobin subunit beta4004
atrial natriuretic peptide receptor 1 precursor4004
ubiquitin carboxyl-terminal hydrolase 2 isoform a7007
Solute carrier family 22 member 1 0305
Purine nucleoside phosphorylase0101
Thymidine kinase, cytosolic0102
POU domain, class 2, transcription factor 20001
Disintegrin and metalloproteinase domain-containing protein 175005
Purine nucleoside phosphorylase0011
Solute carrier family 22 member 60407
Thymidine kinase 0101
Solute carrier family 22 member 80104
Thymidine kinase0101
Chain A, TYROSYL-DNA PHOSPHODIESTERASE130013
Alanine racemase, biosynthetic0001
5-hydroxytryptamine receptor 1D0001
Glutamate receptor ionotropic, NMDA 1 0304
Proton-coupled amino acid transporter 10101
Adenosine deaminase0001
Carbonic anhydrase 40102
Luciferase170017
interleukin 8110011
15-lipoxygenase, partial100010
estrogen receptor 2 (ER beta)170017
cytochrome P450 family 3 subfamily A polypeptide 4220022
pregnane X nuclear receptor370037
G190019
vitamin D (1,25- dihydroxyvitamin D3) receptor220022
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a140014
histone deacetylase 9 isoform 33003
Interferon beta230023
HLA class I histocompatibility antigen, B alpha chain 190019
Nicotinate phosphoribosyltransferase0202
Inositol hexakisphosphate kinase 1190019
cytochrome P450 2C9, partial190019
ORF730011
Chain A, Phospholipase A2 isoform 30011
Chain A, 2-oxoglutarate Oxygenase100010
GTP-binding protein (rab7)0011
ras protein, partial0011
hypothetical protein, conserved2002
glucocorticoid receptor [Homo sapiens]370037
cytochrome P450 2D6150015
glucocerebrosidase2002
Rac1 protein0011
IDH1130013
cell division cycle 42 (GTP binding protein, 25kDa), partial0011
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 19009
DNA polymerase iota isoform a (long)120012
DNA polymerase kappa isoform 1140014
Prostaglandin-H2 D-isomerase0101
Prostaglandin G/H synthase 1 0505
Prostaglandin G/H synthase 2 0202
Epidermal growth factor receptor0314
Fatty acid-binding protein, liver0404
Integrin beta-33104
Myeloperoxidase0101
Seed linoleate 13S-lipoxygenase-10202
Integrin alpha-IIb3104
Glutathione hydrolase 1 proenzyme0101
Substance-P receptor0101
Urotensin-2 receptor0101
4-aminobutyrate aminotransferase, mitochondrial0101
Ras-related protein Rab-2A0011
Prostaglandin G/H synthase 20404
Rho-associated protein kinase 20101
Solute carrier family 22 member 200303
Solute carrier family 22 member 60303
Sigma non-opioid intracellular receptor 10718
Sigma non-opioid intracellular receptor 10011
Beta-1 adrenergic receptor 0011
Urease0101
Beta-2 adrenergic receptor0213
Beta-1 adrenergic receptor0415
Beta-3 adrenergic receptor0213
5-hydroxytryptamine receptor 1A0516
Alpha-1D adrenergic receptor0707
Alpha-1A adrenergic receptor0101
Alpha-1B adrenergic receptor0101
TAR DNA-binding protein 439009
Beta-2 adrenergic receptor0011
ATP-dependent phosphofructokinase120012
cystic fibrosis transmembrane conductance regulator0202
DNA polymerase beta2002
short transient receptor potential channel 6 isoform 10011
5-hydroxytryptamine receptor 40606
Muscarinic acetylcholine receptor M2016424
Muscarinic acetylcholine receptor M4015321
Muscarinic acetylcholine receptor M1010217
Muscarinic acetylcholine receptor M309215
Muscarinic acetylcholine receptor M409114
Muscarinic acetylcholine receptor M509114
Muscarinic acetylcholine receptor M5013319
Muscarinic acetylcholine receptor M2010217
Muscarinic acetylcholine receptor M1016627
Muscarinic acetylcholine receptor M10225
Muscarinic acetylcholine receptor M3014320
5-hydroxytryptamine receptor 2C0606
Muscarinic acetylcholine receptor M40202
5-hydroxytryptamine receptor 70202
Reverse transcriptase/RNaseH 0012
Muscarinic acetylcholine receptor0415
Chain A, Beta-lactamase7007
pregnane X receptor8008
Fumarate hydratase4004
NFKB1 protein, partial4004
PPM1D protein6006
Thrombopoietin3003
farnesoid X nuclear receptor210021
polyprotein4004
67.9K protein8008
Parkin4004
thyroid stimulating hormone receptor150015
peripheral myelin protein 22 isoform 16006
cellular tumor antigen p53 isoform a6006
huntingtin isoform 24004
ras-related protein Rab-9A2002
urokinase-type plasminogen activator precursor5005
plasminogen precursor5005
urokinase plasminogen activator surface receptor precursor5005
Cellular tumor antigen p53320032
Adenosine receptor A30707
DNA (cytosine-5)-methyltransferase 10101
D(1A) dopamine receptor1001
Spike glycoprotein160117
Multidrug and toxin extrusion protein 10505
Histone-lysine N-methyltransferase EHMT20101
acetylcholinesterase160016
SMAD family member 2130013
SMAD family member 3130013
thioredoxin glutathione reductase6006
P531001
survival motor neuron protein isoform d8008
M-phase phosphoprotein 84004
muscleblind-like protein 1 isoform 15005
Protein-arginine deiminase type-40606
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)9009
Sodium-dependent serotonin transporter0404
bromodomain adjacent to zinc finger domain 2B7007
Nuclear hormone receptor family member daf-120011
nuclear factor erythroid 2-related factor 2 isoform 2100010
oxysterols receptor LXR-beta isoform 10011
Thymidine phosphorylase0001
Thymidylate kinase0101
Thymidine kinase0001
Thymidylate kinase0101
Liver carboxylesterase 10001
nuclear receptor ROR-gamma isoform 1110011
transient receptor potential cation channel subfamily V member 11001
Transient receptor potential cation channel subfamily V member 10213
Lysine-specific histone demethylase 1A0101
NADH-ubiquinone oxidoreductase chain 10101
Polyunsaturated fatty acid 5-lipoxygenase0101
Cannabinoid receptor 10303
Acetylcholinesterase0404
Cannabinoid receptor 2 0101
D(2) dopamine receptor0112
Inositol monophosphatase 13003
Potassium voltage-gated channel subfamily A member 10112
Corticotropin-releasing factor receptor 20101
Transient receptor potential cation channel subfamily V member 10214
Transient receptor potential cation channel subfamily V member 40011
Transient receptor potential cation channel subfamily V member 20011
GALC protein3003
thyrotropin-releasing hormone receptor5005
Neuronal acetylcholine receptor subunit alpha-30101
Neuronal acetylcholine receptor subunit alpha-42103
Neuronal acetylcholine receptor subunit alpha-20101
Neuronal acetylcholine receptor subunit beta-22103
Neuronal acetylcholine receptor subunit beta-30101
Neuronal acetylcholine receptor subunit beta-40101
Neuronal acetylcholine receptor subunit alpha-50101
Delta-type opioid receptor0215
Neuronal acetylcholine receptor subunit alpha-60101
Neuronal acetylcholine receptor subunit alpha-90101
Neuronal acetylcholine receptor subunit alpha-70101
Sigma non-opioid intracellular receptor 10011
Muscarinic acetylcholine receptor M30114
Muscarinic acetylcholine receptor M20104
Neuronal acetylcholine receptor subunit alpha-100101
Chain A, Putative fructose-1,6-bisphosphate aldolase4004
Chain A, serum paraoxonase0101
Neutrophil cytosol factor 10101
Carbonic anhydrase 130102
Poly [ADP-ribose] polymerase tankyrase-20101
USP1 protein, partial240024
streptokinase A precursor0044
Dihydroxyacetone phosphate acyltransferase0001
30S ribosomal protein S60415
30S ribosomal protein S70415
50S ribosomal protein L150415
50S ribosomal protein L100415
50S ribosomal protein L110415
50S ribosomal protein L7/L120415
50S ribosomal protein L190415
50S ribosomal protein L10415
50S ribosomal protein L200415
50S ribosomal protein L270415
50S ribosomal protein L280415
50S ribosomal protein L290415
50S ribosomal protein L310415
50S ribosomal protein L31 type B0415
50S ribosomal protein L320415
50S ribosomal protein L330415
50S ribosomal protein L340415
50S ribosomal protein L350415
50S ribosomal protein L360415
30S ribosomal protein S100415
30S ribosomal protein S110415
30S ribosomal protein S120415
30S ribosomal protein S130415
30S ribosomal protein S160415
30S ribosomal protein S180415
30S ribosomal protein S190415
30S ribosomal protein S200415
30S ribosomal protein S20415
30S ribosomal protein S30415
30S ribosomal protein S40415
30S ribosomal protein S50415
30S ribosomal protein S80415
30S ribosomal protein S90415
50S ribosomal protein L130415
50S ribosomal protein L140415
50S ribosomal protein L160415
50S ribosomal protein L230415
30S ribosomal protein S150415
50S ribosomal protein L170415
50S ribosomal protein L210415
50S ribosomal protein L300415
50S ribosomal protein L60415
30S ribosomal protein S140415
30S ribosomal protein S170415
30S ribosomal protein S10415
50S ribosomal protein L180415
50S ribosomal protein L20415
50S ribosomal protein L30415
50S ribosomal protein L240415
50S ribosomal protein L40415
50S ribosomal protein L220415
50S ribosomal protein L50415
30S ribosomal protein S210415
50S ribosomal protein L250415
50S ribosomal protein L36 20415
Methionine--tRNA ligase, mitochondrial0011
Carbonic anhydrase0304
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase0011
hepatocyte nuclear factor 4-alpha isoform 20101
perilipin-50101
perilipin-10101
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a0101
Beta-lactamase0101
Proto-oncogene tyrosine-protein kinase Src0112
3-dehydroquinate dehydratase0011
ATP-citrate synthase 0001
Ribonuclease T0001
Cell death-related nuclease 40001
3-dehydroquinate dehydratase0011
Prolyl 4-hydroxylase0101
Alpha-ketoglutarate-dependent dioxygenase FTO0101
nuclear receptor subfamily 0 group B member 10101
steroidogenic factor 10101
histone-lysine N-methyltransferase 2A isoform 2 precursor2002
relaxin receptor 1 isoform 12002
relaxin receptor 2 isoform 11001
Nuclear receptor subfamily 1 group I member 20066
Rap guanine nucleotide exchange factor 36006
ATP-dependent translocase ABCB108210
5-hydroxytryptamine receptor 1A0101
Solute carrier family 2, facilitated glucose transporter member 10011
Adenylate cyclase type 20011
Adenylate cyclase type 80011
Adenylate cyclase type 10112
Relaxin receptor 10011
Nuclear receptor subfamily 1 group I member 20033
endonuclease IV4004
dopamine D1 receptor5005
flap endonuclease 16006
Glucocorticoid receptor010318
Sex hormone-binding globulin0011
Glycine receptor subunit alpha-1010010
Corticosteroid-binding globulin0202
Glycine receptor subunit beta010010
Glycine receptor subunit alpha-2010010
Glycine receptor subunit alpha-3010010
Thymidine kinase 2 0101
Deoxycytidine kinase0012
Probable deoxycytidylate deaminase0001
Cytidine deaminase0001
AAA family ATPase 0001
Aldo-keto reductase family 1 member B100101
Transient receptor potential cation channel subfamily A member 10011
Dihydrofolate reductase0607
Cytochrome c oxidase subunit 20101
Transthyretin0115
Albumin0123
Interleukin-80101
Calcium/calmodulin-dependent protein kinase type II subunit alpha0101
Fatty acid-binding protein, intestinal0101
Aldo-keto reductase family 1 member B10101
UDP-glucuronosyltransferase 2B70103
UDP-glucuronosyltransferase 1A40102
Sodium- and chloride-dependent GABA transporter 10101
C-X-C chemokine receptor type 10101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Prostaglandin G/H synthase 2 0202
UDP-glucuronosyltransferase 1A30001
UDP-glucuronosyltransferase 2B10 0101
Sodium- and chloride-dependent betaine transporter0101
Prostaglandin G/H synthase 20101
Prostaglandin G/H synthase 1 0202
P2Y purinoceptor 120101
UDP-glucuronosyltransferase 1A70102
UDP-glucuronosyltransferase 1A100102
Chain A, Cruzipain4004
prostaglandin E2 receptor EP2 subtype1001
vitamin D3 receptor isoform VDRA120012
Solute carrier family 22 member 20102
Solute carrier organic anion transporter family member 1A50002
Prostaglandin E2 receptor EP3 subtype0101
Prostaglandin E2 receptor EP4 subtype0101
Prostaglandin E2 receptor EP1 subtype0213
Prostaglandin E2 receptor EP1 subtype0101
Prostaglandin E2 receptor EP4 subtype0213
Prostaglandin F2-alpha receptor0011
Prostaglandin E2 receptor EP4 subtype0112
Prostaglandin E2 receptor EP3 subtype0213
Prostaglandin E2 receptor EP2 subtype0213
Prostacyclin receptor0213
Solute carrier organic anion transporter family member 2A10001
Solute carrier family 22 member 70001
Prostaglandin E2 receptor EP2 subtype0101
Prostaglandin E2 receptor EP2 subtype0112
Solute carrier family 22 member 70001
Solute carrier organic anion transporter family member 2A10001
Solute carrier family 22 member 110103
Solute carrier organic anion transporter family member 1B20001
Solute carrier family 22 member 70001
potassium voltage-gated channel subfamily H member 2 isoform d7007
Aldo-keto reductase family 1 member B10606
Angiotensin-converting enzyme0202
Sodium-dependent noradrenaline transporter 0606
5-hydroxytryptamine receptor 2A0404
Histamine H1 receptor0012
Histamine H1 receptor0202
5-hydroxytryptamine receptor 2B0808
Histamine N-methyltransferase0001
Potassium voltage-gated channel subfamily H member 20808
Sodium channel protein type 5 subunit alpha0101
Solute carrier family 22 member 10101
Nuclear receptor subfamily 3 group C member 3 0202
Calcium release-activated calcium channel protein 10202
Protein orai-20101
Protein orai-30101
Histamine H4 receptor0101
Histamine H3 receptor0001
Solute carrier family 22 member 20101
Potassium voltage-gated channel subfamily A member 30101
Mu-type opioid receptor0529
polyunsaturated fatty acid lipoxygenase ALOX122002
Polyunsaturated fatty acid lipoxygenase ALOX15B3003
P2Y purinoceptor 20011
P2Y purinoceptor 10011
P2Y purinoceptor 40011
P2Y purinoceptor 60011
Chain A, Protein (peroxisome Proliferator Activated Receptor (ppar-delta))0101
Trypsin0303
Coagulation factor VII0303
Aromatase0404
Tissue factor0303
Retinoic acid receptor RXR-alpha0347
Peroxisome proliferator-activated receptor gamma0044
Oxoeicosanoid receptor 10101
Neuromedin-K receptor0112
nonstructural protein 15005
Multidrug and toxin extrusion protein 20101
Motilin receptor0011
acid sphingomyelinase2002
low molecular weight phosphotyrosine protein phosphatase isoform c0101
serine/threonine-protein kinase PLK15005
Motilin receptor0112
ATP-dependent translocase ABCB10404
60 kDa chaperonin0404
60 kDa heat shock protein, mitochondrial0404
Chitinase B0101
ATP-dependent translocase ABCB10404
Low molecular weight phosphotyrosine protein phosphatase0101
10 kDa heat shock protein, mitochondrial0404
Cytochrome P450 1B10101
Thiosulfate sulfurtransferase0404
Lanosterol 14-alpha demethylase0202
60 kDa chaperonin 0404
10 kDa chaperonin 0404
Genome polyprotein 0213
chaperonin-containing TCP-1 beta subunit homolog1001
eyes absent homolog 2 isoform a1001
lethal(3)malignant brain tumor-like protein 1 isoform I2002
Flavin reductase (NADPH)0022
large T antigen0202
transcriptional regulator ERG isoform 34004
twin arginine protein translocation system - TatA protein0002
lysosomal alpha-glucosidase preproprotein2002
peptidyl-prolyl cis-trans isomerase NIMA-interacting 16006
Androgen receptor0909
Chain A, Uracil Phosphoribosyltransferase0101
Skn7p0001
Vpr3003
Solute carrier family 22 member 80001
Amyloid-beta precursor protein1203
Thymidylate synthase0303
HSP40, subfamily A [Plasmodium falciparum 3D7]0001
WRN1001
Caspase 6, apoptosis-related cysteine peptidase0001
isocitrate dehydrogenase 1, partial1001
DNA polymerase eta isoform 14004
Free fatty acid receptor 10022
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E0011
Spike glycoprotein0011
Replicase polyprotein 1ab0022
Transmembrane protease serine 20011
Procathepsin L0011
Alpha-2A adrenergic receptor0505
Replicase polyprotein 1a0011
Replicase polyprotein 1ab0011
Replicase polyprotein 1ab0112
Replicase polyprotein 1ab0112
Alpha-2B adrenergic receptor0505
Alpha-2C adrenergic receptor0101
Sigma intracellular receptor 20101
Cyclic GMP-AMP synthase0101
Angiotensin-converting enzyme 2 0011
Toll-like receptor 90101
Toll-like receptor 70101
Caspase-72002
parathyroid hormone/parathyroid hormone-related peptide receptor precursor3003
caspase-32002
Ornithine decarboxylase0002
Retinoic acid receptor alpha0224
Alpha-1B adrenergic receptor0606
Retinoic acid receptor gamma0224
Retinoic acid receptor beta0224
Cellular retinoic acid-binding protein 20022
Mitogen-activated protein kinase 10314
Retinoic acid receptor RXR-alpha0224
Retinoic acid receptor RXR-beta0224
Retinoic acid receptor RXR-gamma0224
Cellular retinoic acid-binding protein 10203
Alpha-1A adrenergic receptor0606
Cellular retinoic acid-binding protein 10022
Mitogen-activated protein kinase 140112
Rap guanine nucleotide exchange factor 42002
Olfactory receptor 51E20112
Glutamate receptor ionotropic, NMDA 2D0101
Acetylcholinesterase0303
Glutamate receptor ionotropic, NMDA 3B0101
Sodium channel protein type 4 subunit alpha0101
Cholinesterase0303
Glutamate receptor ionotropic, NMDA 2A 0203
Glutamate receptor ionotropic, NMDA 2B0203
Glutamate receptor ionotropic, NMDA 2C0203
Glutamate receptor ionotropic, NMDA 10202
Glutamate receptor ionotropic, NMDA 2A0202
Glutamate receptor ionotropic, NMDA 2B0202
Glutamate receptor ionotropic, NMDA 2C0101
Glutamate receptor ionotropic, NMDA 2D0203
Glutamate receptor ionotropic, NMDA 3A0101
Glutamate receptor ionotropic, NMDA 3B0203
Glutamate receptor ionotropic, NMDA 3A0203
Chain A, Lectin0011
Chain A, Lectin0011
Chain A, Lectin0011
Chain A, Lectin0011
Chain A, ERYTHRINA CRISTA-GALLI LECTIN0011
Chain A, ERYTHRINA CRISTA-GALLI LECTIN0011
Chain A, cellulase0011
Chain A, cellulase0011
Chain A, Galectin-30011
Chain A, Anti-tumor lectin0101
Galectin-30101
Galectin-90011
Galectin-80011
Beta-galactoside-binding lectin0101
Galectin-10113
Galectin-30112
Galectin-30113
Galectin-70011
Alpha 1,4 galactosyltransferase0001
caspase 7, apoptosis-related cysteine protease3003
caspase-33003
Sterol O-acyltransferase 10101
Fatty acid-binding protein, heart0202
Fatty acid-binding protein, adipocyte0202
Tyrosine-protein phosphatase non-receptor type 70101
Sterol O-acyltransferase 10101
Aldo-keto reductase family 1 member C30101
Nuclear receptor subfamily 4 group A member 20011
Dual specificity protein phosphatase 30101
Fatty acid-binding protein 50101
Peroxisome proliferator-activated receptor alpha1001
Free fatty acid receptor 40011
Chain A, Breast cancer type 1 susceptibility protein2002
cytochrome P450 2C19 precursor6006
microphthalmia-associated transcription factor isoform 90101
caspase-1 isoform alpha precursor3003
Solute carrier organic anion transporter family member 2B1 0203
Tumor necrosis factor0112
Neuraminidase0101
Platelet-activating factor receptor1001
Cystathionine gamma-lyase0101
Caspase-73003
Solute carrier organic anion transporter family member 1B30204
Cystine/glutamate transporter0202
Hydroxyacid oxidase 10101
Solute carrier organic anion transporter family member 1B10406
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
ClpP1001
Thymidylate synthase 0101
alpha-galactosidase1001
Thymidylate synthase 0101
importin subunit beta-1 isoform 11001
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0101
snurportin-11001
transactivating tegument protein VP16 [Human herpesvirus 1]0101
nuclear receptor coactivator 3 isoform a0101
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0304
Dihydrofolate reductase 0202
Dihydrofolate reductase0303
Dihydrofolate reductase0101
Dihydrofolate reductase0405
Thymidylate synthase0101
Tyrosine-protein kinase ABL10022
Thymidylate synthase0303
Bifunctional dihydrofolate reductase-thymidylate synthase0303
5-hydroxytryptamine receptor 2C0102
High mobility group protein B10011
Dihydrofolate reductase0303
Thymidylate synthase0202
Dihydrofolate reductase0426
Glucose-6-phosphate 1-dehydrogenase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0303
Folate receptor beta0101
5-hydroxytryptamine receptor 2A0303
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Dihydrofolate reductase0506
Histidine decarboxylase0112
Trifunctional purine biosynthetic protein adenosine-30101
Cyclin-dependent kinase 20022
Bifunctional purine biosynthesis protein ATIC0303
Multidrug resistance-associated protein 1 0102
Delta-type opioid receptor0314
Mu-type opioid receptor0415
Kappa-type opioid receptor0314
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
6-phosphogluconate dehydrogenase, decarboxylating0101
Solute carrier organic anion transporter family member 1A30002
Dihydrofolate reductase0202
Pteridine reductase 10101
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0203
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Dihydrofolate reductase 0303
Dihydrofolate reductase0203
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Multidrug resistance associated protein0102
Broad substrate specificity ATP-binding cassette transporter ABCG20304
heat shock protein HSP 90-alpha isoform 20001
Metabotropic glutamate receptor 60101
Cytochrome P450 1A20101
Chymotrypsinogen A0101
Beta-lactamase0101
Receptor tyrosine-protein kinase erbB-20101
Cytochrome P450 1A2 0101
Steroid 17-alpha-hydroxylase/17,20 lyase0101
Tyrosine-protein kinase Fyn0112
Heme oxygenase 1 0101
Epoxide hydrolase 10001
D(2) dopamine receptor0303
Indoleamine 2,3-dioxygenase 10101
Substance-K receptor0202
D(1A) dopamine receptor0202
D(4) dopamine receptor0202
Aromatase0011
Heme oxygenase 20101
Thromboxane-A synthase 0202
Histamine H2 receptor0202
Substance-P receptor0202
5-hydroxytryptamine receptor 1B0202
Indoleamine 2,3-dioxygenase 10202
Melanocortin receptor 40202
Melanocortin receptor 50202
Cytochrome P450 2C190415
D(3) dopamine receptor0303
Malate dehydrogenase, cytoplasmic0101
Delta-type opioid receptor0428
Kappa-type opioid receptor0418
Melanocortin receptor 30202
Type-2 angiotensin II receptor0202
5-hydroxytryptamine receptor 60202
Beta-lactamase TEM0101
Cytochrome P450 1440011
Steroid C26-monooxygenase0011
Steroid C26-monooxygenase0011
Mycocyclosin synthase0011
Lanosterol 14-alpha demethylase0011
Sodium-dependent dopamine transporter 0202
Indoleamine 2,3-dioxygenase 20202
heat shock protein 90, putative0001
methionyl-tRNA synthetase, putative0101
Histone deacetylase 30202
Nuclear receptor corepressor 10101
Integrin beta-10101
Leukotriene A-4 hydrolase0101
Integrin alpha-40101
Histone deacetylase 40101
Histone deacetylase 10202
Histone deacetylase 70101
Histone deacetylase 20202
Histone deacetylase 11 0101
Histone deacetylase 80101
Histone deacetylase 60101
Histone deacetylase 50101
Nuclear receptor corepressor 20101
Chain A, Inosine-5'-Monophosphate Dehydrogenase 20101
Inosine-5'-monophosphate dehydrogenase 20213
Glutamate receptor 10101
Glutamate receptor 30101
Glutamate receptor 40101
Inosine-5'-monophosphate dehydrogenase 1 0202
Alpha-synuclein4206
Inosine-5'-monophosphate dehydrogenase0102
UDP-glucuronosyltransferase 1A80002
5-hydroxytryptamine receptor 3E0101
5-hydroxytryptamine receptor 3B0101
Kappa-type opioid receptor0213
Kappa-type opioid receptor0203
Nociceptin receptor0101
Mu-type opioid receptor0214
5-hydroxytryptamine receptor 3A0101
Mu-type opioid receptor0315
5-hydroxytryptamine receptor 3D0101
5-hydroxytryptamine receptor 3C0101
Cholinesterase0202
Sodium/iodide cotransporter0101
Tyrosine-protein kinase JAK20112
Tyrosine-protein kinase JAK10112
Chain A, AMINOPEPTIDASE0101
Chain A, AMINOPEPTIDASE0101
Voltage-dependent calcium channel subunit alpha-2/delta-10101
Plasma kallikrein0001
Alkaline phosphatase, tissue-nonspecific isozyme0101
Alkaline phosphatase, tissue-nonspecific isozyme 0101
Intestinal-type alkaline phosphatase0101
Intestinal-type alkaline phosphatase0101
5'-nucleotidase0101
Carbonic anhydrase0001
E3 ubiquitin-protein ligase XIAP0101
Large neutral amino acids transporter small subunit 10102
SLC16A10 protein0001
Carbonic anhydrase 0001
Carbonic anhydrase-like protein, putative0001
Carbonic anhydrase0001
Carbonic anhydrase0001
Large neutral amino acids transporter small subunit 1 0101
Carbonic anhydrase 0001
Monocarboxylate transporter 100001
Phospholipase A-2-activating protein0101
beta-2 adrenergic receptor1001
mu-type opioid receptor isoform MOR-10011
5-hydroxytryptamine receptor 2A0011
Cytochrome P450 2A60112
Muscarinic acetylcholine receptor DM10202
Cytochrome P450 2A130112
Muscarinic acetylcholine receptor M50101
Polyunsaturated fatty acid 5-lipoxygenase0101
luciferase0001
Estrogen receptor0202
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Mineralocorticoid receptor 0213
Androgen receptor0202
Glutamine synthetase0011
Nociceptin receptor0011
Estrogen receptor beta0202
Amine oxidase [flavin-containing] A0101
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR0011
Retinol-binding protein 40011
Beta-lactoglobulin0011
Chain A, 6,7-Dimethyl-8-ribityllumazine Synthase0011
Chain B, 6,7-Dimethyl-8-ribityllumazine Synthase0011
Chain H, Immunoglobulin Igg1 Heavy chain0011
Chain L, Immunoglobulin Igg1 Lambda Light Chain0011
Chain A, DODECIN0011
Chain A, DODECIN0011
Chain C, DODECIN0011
Chain E, DODECIN0011
NPYLR7B0011
tumor necrosis factor1001
nuclear factor NF-kappa-B p105 subunit isoform 11001
Riboflavin-binding protein0112
Integrin beta-20101
Intercellular adhesion molecule 10101
Integrin alpha-L0101
Bone morphogenetic protein receptor type-1B0011
Cell division cycle 7-related protein kinase0011
Serine/threonine-protein kinase PLK40011
ATP-dependent RNA helicase DDX3X0011
Pyridoxal kinase0011
Citron Rho-interacting kinase0011
Serine/threonine-protein kinase Chk10011
Aurora kinase A0112
Cyclin-G-associated kinase0011
Ephrin type-B receptor 60011
Peroxisomal acyl-coenzyme A oxidase 30011
Receptor-interacting serine/threonine-protein kinase 20011
Mitotic checkpoint serine/threonine-protein kinase BUB10011
Dynamin-like 120 kDa protein, mitochondrial0011
Eukaryotic translation initiation factor 5B0011
Rho-associated protein kinase 20011
Serine/threonine-protein kinase ULK10011
Serine/threonine-protein kinase/endoribonuclease IRE10011
Ribosomal protein S6 kinase alpha-50011
U5 small nuclear ribonucleoprotein 200 kDa helicase0011
Ribosomal protein S6 kinase alpha-40011
Serine/threonine-protein kinase 160011
Cyclin-dependent kinase-like 50011
Serine/threonine-protein kinase 100011
Serine/threonine-protein kinase D30011
Structural maintenance of chromosomes protein 20011
Mitogen-activated protein kinase kinase kinase 60011
Mitogen-activated protein kinase kinase kinase kinase 40011
Serine/threonine-protein kinase LATS10011
Serine/threonine-protein kinase PAK 40011
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10101
High affinity nerve growth factor receptor0011
ADP/ATP translocase 20011
Protein kinase C beta type0011
Insulin receptor0011
Tyrosine-protein kinase Lck0011
Cyclin-dependent kinase 10011
Eukaryotic translation initiation factor 4E0011
Glycogen phosphorylase, liver form0011
Tyrosine-protein kinase Fes/Fps0011
Adenine phosphoribosyltransferase0011
Tyrosine-protein kinase Yes0011
Tyrosine-protein kinase Lyn0011
Proto-oncogene tyrosine-protein kinase receptor Ret0011
Insulin-like growth factor 1 receptor0011
Signal recognition particle receptor subunit alpha0011
Cytochrome c1, heme protein, mitochondrial0011
Hepatocyte growth factor receptor0011
Tyrosine-protein kinase HCK0011
Platelet-derived growth factor receptor beta0011
Tyrosine-protein kinase Fgr0011
Serine/threonine-protein kinase A-Raf0011
Glycogen phosphorylase, brain form0011
Breakpoint cluster region protein0011
Serine/threonine-protein kinase pim-10011
Fibroblast growth factor receptor 10011
DNA topoisomerase 2-alpha0011
Cyclin-dependent kinase 40011
ADP/ATP translocase 30011
cAMP-dependent protein kinase type II-alpha regulatory subunit0011
Serine/threonine-protein kinase B-raf0011
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform0011
Ribosyldihydronicotinamide dehydrogenase [quinone]0011
Tyrosine-protein kinase Fer0011
Protein kinase C alpha type0011
cAMP-dependent protein kinase catalytic subunit alpha0011
General transcription and DNA repair factor IIH helicase subunit XPD0011
Casein kinase II subunit alpha'0011
Ras-related protein Rab-6A0011
Ephrin type-A receptor 10011
Multifunctional protein ADE20011
cAMP-dependent protein kinase catalytic subunit beta0011
Ferrochelatase, mitochondrial0011
Ribosomal protein S6 kinase beta-10011
Beta-adrenergic receptor kinase 10011
Probable ATP-dependent RNA helicase DDX60011
Peptidyl-prolyl cis-trans isomerase FKBP1A0101
Mitogen-activated protein kinase 3 0011
MAP/microtubule affinity-regulating kinase 30011
Ephrin type-A receptor 20011
Ephrin type-B receptor 20011
Non-receptor tyrosine-protein kinase TYK20011
UMP-CMP kinase 0011
Phosphatidylethanolamine-binding protein 10011
Wee1-like protein kinase0011
Heme oxygenase 20011
S-adenosylmethionine synthase isoform type-20011
DnaJ homolog subfamily A member 10011
RAC-alpha serine/threonine-protein kinase0011
RAC-beta serine/threonine-protein kinase0011
Dual specificity protein kinase TTK0011
DNA replication licensing factor MCM40011
Myosin-100011
Dual specificity mitogen-activated protein kinase kinase 20011
Receptor-type tyrosine-protein kinase FLT30011
Bone morphogenetic protein receptor type-1A0011
Activin receptor type-1B0011
TGF-beta receptor type-10011
Serine/threonine-protein kinase receptor R30011
TGF-beta receptor type-20011
Electron transfer flavoprotein subunit beta0011
Tyrosine-protein kinase CSK0011
Glycine--tRNA ligase0011
Protein kinase C iota type0011
Exosome RNA helicase MTR40011
Serine/threonine-protein kinase mTOR0213
Tyrosine-protein kinase Tec0011
Tyrosine-protein kinase ABL20011
Tyrosine-protein kinase FRK0011
G protein-coupled receptor kinase 60011
Tyrosine-protein kinase SYK0011
26S proteasome regulatory subunit 6B0011
Mitogen-activated protein kinase 80011
Mitogen-activated protein kinase 90011
Dual specificity mitogen-activated protein kinase kinase 30011
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha0011
Casein kinase I isoform alpha0011
Casein kinase I isoform delta0011
MAP kinase-activated protein kinase 20011
Elongation factor Tu, mitochondrial0011
Choline-phosphate cytidylyltransferase A0011
Cysteine--tRNA ligase, cytoplasmic0011
Casein kinase I isoform epsilon0011
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial0011
Dual specificity protein kinase CLK10011
Dual specificity protein kinase CLK20011
Dual specificity protein kinase CLK30011
Glycogen synthase kinase-3 alpha0011
Glycogen synthase kinase-3 beta0011
Cyclin-dependent kinase 70011
Cyclin-dependent kinase 90011
Ras-related protein Rab-27A0011
Interleukin-1 receptor-associated kinase 10011
Ribosomal protein S6 kinase alpha-30011
Serine/threonine-protein kinase Nek20011
Serine/threonine-protein kinase Nek30011
Dual specificity mitogen-activated protein kinase kinase 60011
Serine/threonine-protein kinase PLK10011
LIM domain kinase 10011
LIM domain kinase 20011
Mitogen-activated protein kinase 100011
Tyrosine--tRNA ligase, cytoplasmic0011
5'-AMP-activated protein kinase subunit gamma-10011
Ephrin type-B receptor 30011
Ephrin type-A receptor 50011
Ephrin type-B receptor 40011
Ephrin type-A receptor 40011
Adenylate kinase 2, mitochondrial0011
Adenosine kinase0011
Ras-related protein Rab-100011
Actin-related protein 30011
Actin-related protein 20011
GTP-binding nuclear protein Ran0011
Peptidyl-prolyl cis-trans isomerase FKBP1A0426
Peptidyl-prolyl cis-trans isomerase FKBP1B0022
Casein kinase I isoform gamma-20011
Cyclin-dependent kinase 60011
Cyclin-dependent-like kinase 5 0011
Cyclin-dependent kinase 160011
Cyclin-dependent kinase 170011
ATP-dependent 6-phosphofructokinase, platelet type0011
Dual specificity mitogen-activated protein kinase kinase 10011
DNA topoisomerase 2-beta0011
Protein kinase C theta type0011
Activin receptor type-10011
Macrophage-stimulating protein receptor0011
Focal adhesion kinase 10011
Protein kinase C zeta type0011
Protein kinase C delta type0011
Tyrosine-protein kinase BTK0011
Cyclin-dependent kinase 180011
Activated CDC42 kinase 10011
Epithelial discoidin domain-containing receptor 10011
Mitogen-activated protein kinase kinase kinase kinase 20011
Tyrosine-protein kinase Mer0011
Serine/threonine-protein kinase 40011
5'-AMP-activated protein kinase catalytic subunit alpha-10011
Dual specificity mitogen-activated protein kinase kinase 50011
Mitogen-activated protein kinase 70011
Serine/threonine-protein kinase PAK 20011
Serine/threonine-protein kinase 30011
Mitogen-activated protein kinase kinase kinase 10011
Integrin-linked protein kinase0011
Peptidyl-prolyl cis-trans isomerase FKBP50202
Rho-associated protein kinase 10011
Non-receptor tyrosine-protein kinase TNK10011
Calcium/calmodulin-dependent protein kinase type II subunit gamma0011
Calcium/calmodulin-dependent protein kinase type II subunit delta0011
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0011
Activin receptor type-2B0011
Bone morphogenetic protein receptor type-20011
Protein-tyrosine kinase 60011
cGMP-dependent protein kinase 1 0011
Cyclin-dependent kinase 130011
Inhibitor of nuclear factor kappa-B kinase subunit epsilon0011
Protein-tyrosine kinase 2-beta0011
Maternal embryonic leucine zipper kinase0011
Structural maintenance of chromosomes protein 1A0011
Chromodomain-helicase-DNA-binding protein 40011
Peroxisomal acyl-coenzyme A oxidase 10011
Delta(24)-sterol reductase0011
Ribosomal protein S6 kinase alpha-10011
Dual specificity testis-specific protein kinase 10011
Myosin light chain kinase, smooth muscle0011
Mitogen-activated protein kinase 110011
Serine/threonine-protein kinase STK110011
Serine/threonine-protein kinase N10011
Serine/threonine-protein kinase N20011
Calcium/calmodulin-dependent protein kinase type IV0011
Mitogen-activated protein kinase kinase kinase 110011
Discoidin domain-containing receptor 20011
AP2-associated protein kinase 10011
Myosin light chain kinase 30011
Uncharacterized aarF domain-containing protein kinase 50011
Programmed cell death protein 40011
Putative heat shock protein HSP 90-beta 20011
Serine/threonine-protein kinase MRCK alpha0011
Serine/threonine-protein kinase MRCK gamma0011
Acyl-CoA dehydrogenase family member 100011
Serine/threonine-protein kinase N30011
Serine/threonine-protein kinase ULK30011
Uncharacterized protein FLJ452520011
Acyl-CoA dehydrogenase family member 110011
Serine/threonine-protein kinase/endoribonuclease IRE20011
Serine/threonine-protein kinase MARK20011
ATP-dependent RNA helicase DHX300011
Serine/threonine-protein kinase TAO10011
STE20-related kinase adapter protein alpha0011
Myosin-140011
AarF domain-containing protein kinase 10011
Mitogen-activated protein kinase kinase kinase kinase 30011
MAP kinase-activated protein kinase 50011
Regulatory-associated protein of mTOR0101
Misshapen-like kinase 10011
Atypical kinase COQ8A, mitochondrial0011
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma0011
Mitogen-activated protein kinase 150011
Serine/threonine-protein kinase Nek90011
ATP-dependent RNA helicase DDX10011
Mitogen-activated protein kinase kinase kinase kinase 10011
Aurora kinase B0011
MAP/microtubule affinity-regulating kinase 40011
Calcium/calmodulin-dependent protein kinase type 1G0011
Serine/threonine-protein kinase Nek10011
PAS domain-containing serine/threonine-protein kinase0011
Calcium/calmodulin-dependent protein kinase kinase 20011
EKC/KEOPS complex subunit TP53RK0011
Dual specificity testis-specific protein kinase 20011
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase0011
Mitogen-activated protein kinase kinase kinase 50011
Mitogen-activated protein kinase kinase kinase 30011
Eukaryotic translation initiation factor 2-alpha kinase 10011
Target of rapamycin complex subunit LST80101
Nucleolar GTP-binding protein 10011
Serine/threonine-protein kinase D20011
RNA cytidine acetyltransferase0011
Serine/threonine-protein kinase SIK20011
STE20-like serine/threonine-protein kinase 0011
Serine/threonine-protein kinase TAO30011
dCTP pyrophosphatase 10011
Dual specificity protein kinase CLK40011
Casein kinase I isoform gamma-10011
Serine/threonine-protein kinase mTOR 0101
Phenylalanine--tRNA ligase beta subunit0011
Isoleucine--tRNA ligase, mitochondrial0011
BMP-2-inducible protein kinase0011
Obg-like ATPase 10011
Midasin0011
Interleukin-1 receptor-associated kinase 40011
Mitogen-activated protein kinase kinase kinase 200011
Cyclin-dependent kinase 120011
Serine/threonine-protein kinase 260011
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial0011
Serine/threonine-protein kinase NLK0011
5'-AMP-activated protein kinase subunit gamma-20011
Serine/threonine-protein kinase TBK10011
Septin-90011
Ribosomal protein S6 kinase alpha-60011
TRAF2 and NCK-interacting protein kinase0011
Serine/threonine-protein kinase TAO20011
Serine/threonine-protein kinase ICK0011
RAC-gamma serine/threonine-protein kinase0011
Serine/threonine-protein kinase SIK30011
Mitogen-activated protein kinase kinase kinase 20011
Thyroid hormone receptor-associated protein 30011
Dual specificity tyrosine-phosphorylation-regulated kinase 1B0011
Mitogen-activated protein kinase kinase kinase kinase 50011
Receptor-interacting serine/threonine-protein kinase 30011
Serine/threonine-protein kinase MRCK beta0011
Interleukin-1 receptor-associated kinase 30011
Serine/threonine-protein kinase 240011
Casein kinase I isoform gamma-30011
Mitogen-activated protein kinase kinase kinase 40011
Carbonic anhydrase 0101
Carbonic anhydrase 0101
Chain A, MALTOPORIN0011
Chain B, MALTOPORIN0011
exodeoxyribonuclease V subunit RecD0101
exodeoxyribonuclease V subunit RecB0101
exodeoxyribonuclease V subunit RecC0101
ATP-dependent 6-phosphofructokinase0101
Dihydropteroate synthase0101
Endothelin-1 receptor0101
Protease 0112
Chain A, Glutathione S-transferase0101
Interstitial collagenase0101
Fibroblast growth factor 10011
Caspase-10101
Sodium/bile acid cotransporter0202
Cytochrome P450 3A50101
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform0101
Splicing factor 3B subunit 30101
C-8 sterol isomerase0101
Squalene monooxygenase 0101
Squalene monooxygenase0202
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0101
Taste receptor type 2 member 380012
Chain X, Thyroid hormone receptor beta-10011
Chain X, Thyroid hormone receptor beta-10011
apical membrane antigen 1, AMA11001
Solute carrier organic anion transporter family member 1A40001
Thyroid hormone receptor alpha0011
Thyroid hormone receptor beta0011
Proliferating cell nuclear antigen0101
Malate dehydrogenase, mitochondrial0101
Solute carrier organic anion transporter family member 1A20001
Solute carrier organic anion transporter family member 4C10101
Monocarboxylate transporter 80001
Bile acid receptor0112
Solute carrier organic anion transporter family member 1C10001
Chain A, Nuclear Receptor ROR-beta0101
Ornithine decarboxylase0001
Retinoic acid receptor alpha0227
Retinoic acid receptor beta0227
Retinoic acid receptor gamma 0227
Alpha-1A adrenergic receptor0101
Alpha-1D adrenergic receptor0101
Retinoic acid receptor RXR-beta0224
Nuclear receptor ROR-alpha0101
Retinoic acid receptor RXR-gamma0224
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 10213
Nuclear receptor ROR-beta0101
Chain A, Dihydrofolate Reductase0011
Chain A, Dihydrofolate reductase0101
Chain A, dihydrofolate reductase (DHFR)0101
Chain A, Dihydrofolate reductase0101
Chain A, Dihydrofolate reductase0101
Dihydrofolate reductase 0102
Dihydrofolate reductase type 10102
Dihydrofolate reductase0101
Dihydrofolate reductase0101
NH(3)-dependent NAD(+) synthetase0101
Dihydrofolate reductase type 1 from Tn40030101
Dipeptidyl peptidase 40101
Dihydrofolate reductase0101
Dipeptidyl peptidase 40101
5-hydroxytryptamine receptor 2B0101
Metabotropic glutamate receptor 50101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Trace amine-associated receptor 50011
Dihydrofolate reductase 0101
Dihydrofolate reductase 0101
Urease subunit alpha0101
Urease subunit beta0101
Ubiquitin carboxyl-terminal hydrolase 20101
Vitamin D3 receptor0112
Guanine nucleotide-binding protein G1001
Ileal sodium/bile acid cotransporter0101
G-protein coupled bile acid receptor 10011
CDGSH iron-sulfur domain-containing protein 10202
M1-family alanyl aminopeptidase0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]