Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
hypoxia-inducible factor 1 alpha subunit | 3 | 0 | 0 | 3 |
RAR-related orphan receptor gamma | 8 | 0 | 0 | 8 |
GLI family zinc finger 3 | 8 | 0 | 0 | 8 |
AR protein | 11 | 0 | 0 | 11 |
aldehyde dehydrogenase 1 family, member A1 | 6 | 0 | 0 | 6 |
retinoic acid nuclear receptor alpha variant 1 | 8 | 0 | 0 | 8 |
retinoid X nuclear receptor alpha | 8 | 0 | 0 | 8 |
estrogen nuclear receptor alpha | 10 | 0 | 0 | 10 |
peroxisome proliferator-activated receptor delta | 5 | 0 | 0 | 5 |
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 5 | 0 | 0 | 5 |
activating transcription factor 6 | 3 | 0 | 0 | 3 |
v-jun sarcoma virus 17 oncogene homolog (avian) | 5 | 0 | 0 | 5 |
Histone H2A.x | 6 | 0 | 0 | 6 |
thyroid hormone receptor beta isoform a | 4 | 0 | 0 | 4 |
heat shock protein beta-1 | 3 | 0 | 0 | 3 |
nuclear factor erythroid 2-related factor 2 isoform 1 | 7 | 0 | 0 | 7 |
lamin isoform A-delta10 | 7 | 0 | 0 | 7 |
Voltage-dependent calcium channel gamma-2 subunit | 6 | 0 | 0 | 6 |
Glutamate receptor 2 | 6 | 0 | 0 | 6 |
estrogen-related nuclear receptor alpha | 9 | 0 | 0 | 9 |
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 3 | 0 | 0 | 3 |
endonuclease IV | 1 | 0 | 0 | 1 |
glp-1 receptor, partial | 4 | 0 | 0 | 4 |
thioredoxin reductase | 4 | 0 | 0 | 4 |
phosphopantetheinyl transferase | 4 | 0 | 0 | 4 |
USP1 protein, partial | 4 | 0 | 0 | 4 |
TDP1 protein | 8 | 0 | 0 | 8 |
nuclear receptor subfamily 1, group I, member 3 | 8 | 0 | 0 | 8 |
cytochrome P450 family 3 subfamily A polypeptide 4 | 5 | 0 | 0 | 5 |
EWS/FLI fusion protein | 9 | 0 | 0 | 9 |
glucocorticoid receptor [Homo sapiens] | 5 | 0 | 0 | 5 |
G | 3 | 0 | 0 | 3 |
67.9K protein | 3 | 0 | 0 | 3 |
LMP1 [Human herpesvirus 4] | 0 | 0 | 0 | 3 |
euchromatic histone-lysine N-methyltransferase 2 | 5 | 0 | 0 | 5 |
chromobox protein homolog 1 | 6 | 0 | 0 | 6 |
nuclear factor erythroid 2-related factor 2 isoform 2 | 4 | 0 | 0 | 4 |
thyroid hormone receptor beta isoform 2 | 8 | 0 | 0 | 8 |
nuclear receptor coactivator 1 isoform 1 [Homo sapiens] | 0 | 3 | 0 | 3 |
serine/threonine-protein kinase mTOR isoform 1 | 1 | 0 | 0 | 1 |
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | 2 | 0 | 0 | 2 |
DNA polymerase iota isoform a (long) | 5 | 0 | 0 | 5 |
transactivating tegument protein VP16 [Human herpesvirus 1] | 0 | 3 | 0 | 3 |
geminin | 6 | 0 | 0 | 6 |
peripheral myelin protein 22 | 3 | 0 | 0 | 3 |
nuclear receptor coactivator 3 isoform a | 0 | 3 | 0 | 3 |
Thymidine kinase 2, mitochondrial | 0 | 1 | 0 | 1 |
ATP-binding cassette sub-family C member 3 | 0 | 7 | 0 | 7 |
Multidrug resistance-associated protein 4 | 0 | 7 | 0 | 8 |
Bile salt export pump | 0 | 8 | 0 | 8 |
Interferon beta | 3 | 0 | 0 | 3 |
HLA class I histocompatibility antigen, B alpha chain | 3 | 0 | 0 | 3 |
Thymidine kinase, cytosolic | 0 | 1 | 0 | 1 |
Cellular tumor antigen p53 | 8 | 0 | 0 | 8 |
Thymidine kinase | 0 | 1 | 0 | 1 |
Thymidylate synthase | 0 | 2 | 0 | 3 |
Cytochrome P450 3A4 | 0 | 3 | 0 | 3 |
Thymidine kinase | 0 | 1 | 0 | 1 |
Deoxycytidine kinase | 0 | 0 | 0 | 1 |
Probable deoxycytidylate deaminase | 0 | 0 | 0 | 1 |
Cytidine deaminase | 0 | 1 | 0 | 2 |
D(1A) dopamine receptor | 1 | 0 | 0 | 1 |
E3 ubiquitin-protein ligase Mdm2 | 0 | 1 | 0 | 1 |
Enoyl-[acyl-carrier-protein] reductase [NADH] | 0 | 1 | 0 | 1 |
Inositol hexakisphosphate kinase 1 | 3 | 0 | 0 | 3 |
Canalicular multispecific organic anion transporter 1 | 0 | 8 | 0 | 9 |
Ataxin-2 | 5 | 0 | 0 | 5 |
Thymidine kinase | 0 | 1 | 0 | 1 |
Deoxynucleoside kinase | 0 | 1 | 0 | 1 |
cytochrome P450 2C9, partial | 3 | 0 | 0 | 3 |
ATP-dependent phosphofructokinase | 2 | 0 | 0 | 2 |
SMAD family member 2 | 2 | 0 | 0 | 2 |
SMAD family member 3 | 2 | 0 | 0 | 2 |
caspase 7, apoptosis-related cysteine protease | 2 | 0 | 0 | 2 |
progesterone receptor | 6 | 0 | 0 | 6 |
pregnane X nuclear receptor | 7 | 0 | 0 | 7 |
peroxisome proliferator activated receptor gamma | 5 | 0 | 0 | 5 |
vitamin D (1,25- dihydroxyvitamin D3) receptor | 4 | 0 | 0 | 4 |
caspase-3 | 2 | 0 | 0 | 2 |
thyroid stimulating hormone receptor | 3 | 0 | 0 | 3 |
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | 2 | 0 | 0 | 2 |
urokinase-type plasminogen activator precursor | 2 | 0 | 0 | 2 |
plasminogen precursor | 2 | 0 | 0 | 2 |
urokinase plasminogen activator surface receptor precursor | 2 | 0 | 0 | 2 |
Prothrombin | 0 | 0 | 0 | 1 |
Regulatory protein E2 | 0 | 0 | 1 | 1 |
ATP-dependent translocase ABCB1 | 0 | 1 | 0 | 1 |
ATP-dependent translocase ABCB1 | 0 | 2 | 0 | 3 |
DNA topoisomerase 1 | 0 | 1 | 0 | 2 |
DNA topoisomerase 2-alpha | 0 | 1 | 1 | 7 |
Cytochrome P450 2C9 | 0 | 1 | 0 | 1 |
Polyunsaturated fatty acid lipoxygenase ALOX15 | 0 | 1 | 0 | 1 |
DNA topoisomerase 2 | 0 | 0 | 0 | 1 |
ATP-dependent translocase ABCB1 | 0 | 1 | 0 | 1 |
UDP-glucuronosyltransferase 1A1 | 0 | 0 | 0 | 1 |
Serum paraoxonase/arylesterase 1 | 0 | 2 | 0 | 2 |
Glutamate receptor ionotropic, NMDA 1 | 0 | 1 | 0 | 2 |
Caspase-3 | 0 | 1 | 0 | 1 |
Glutamate receptor ionotropic, NMDA 2A | 0 | 0 | 0 | 1 |
Glutamate receptor ionotropic, NMDA 2B | 0 | 0 | 0 | 1 |
Glutamate receptor ionotropic, NMDA 2C | 0 | 0 | 0 | 1 |
DNA topoisomerase 2-alpha | 0 | 0 | 0 | 1 |
DNA topoisomerase 2-beta | 0 | 1 | 1 | 8 |
Glutamate receptor ionotropic, NMDA 2D | 0 | 0 | 0 | 1 |
Tubulin beta-2B chain | 0 | 1 | 0 | 1 |
Integrase | 0 | 1 | 0 | 1 |
Similar to alpha-tubulin isoform 1 | 0 | 1 | 0 | 1 |
Similar to alpha-tubulin isoform 1 | 0 | 1 | 0 | 1 |
Glutamate receptor ionotropic, NMDA 3B | 0 | 0 | 0 | 1 |
ATPase family AAA domain-containing protein 5 | 4 | 0 | 0 | 4 |
Solute carrier organic anion transporter family member 1B3 | 0 | 2 | 0 | 3 |
Glutamate receptor ionotropic, NMDA 3A | 0 | 0 | 0 | 1 |
Chain A, Beta-lactamase | 2 | 0 | 0 | 2 |
GALC protein | 2 | 0 | 0 | 2 |
acetylcholinesterase | 3 | 0 | 0 | 3 |
estrogen receptor 2 (ER beta) | 5 | 0 | 0 | 5 |
cytochrome P450 2D6 | 4 | 0 | 0 | 4 |
cellular tumor antigen p53 isoform a | 2 | 0 | 0 | 2 |
Integrin beta-3 | 2 | 0 | 0 | 2 |
Integrin alpha-IIb | 2 | 0 | 0 | 2 |
Cereblon isoform 4 | 0 | 4 | 0 | 4 |
Bromodomain-containing protein 4 | 0 | 1 | 0 | 1 |
Tyrosine-protein kinase ABL1 | 0 | 0 | 1 | 3 |
Breakpoint cluster region protein | 0 | 0 | 0 | 2 |
DNA-binding protein Ikaros | 0 | 0 | 2 | 7 |
DNA damage-binding protein 1 | 0 | 3 | 2 | 5 |
Protein cereblon | 0 | 6 | 3 | 14 |
Zinc finger protein Aiolos | 0 | 0 | 2 | 2 |
Chain A, AMINOPEPTIDASE | 0 | 1 | 0 | 1 |
Chain A, AMINOPEPTIDASE | 0 | 1 | 0 | 1 |
Chain A, Leucine Aminopeptidase | 0 | 1 | 0 | 1 |
Alkaline phosphatase, tissue-nonspecific isozyme | 0 | 1 | 0 | 1 |
Intestinal-type alkaline phosphatase | 0 | 1 | 0 | 1 |
Large neutral amino acids transporter small subunit 1 | 0 | 1 | 0 | 1 |
Proton-coupled amino acid transporter 1 | 0 | 2 | 0 | 3 |
Phospholipase A-2-activating protein | 0 | 1 | 0 | 1 |
Chain A, TYROSYL-DNA PHOSPHODIESTERASE | 4 | 0 | 0 | 4 |
15-lipoxygenase, partial | 3 | 0 | 0 | 3 |
Fumarate hydratase | 1 | 0 | 0 | 1 |
GLS protein | 2 | 0 | 0 | 2 |
thioredoxin glutathione reductase | 2 | 0 | 0 | 2 |
Smad3 | 1 | 0 | 0 | 1 |
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 2 | 0 | 0 | 2 |
farnesoid X nuclear receptor | 5 | 0 | 0 | 5 |
polyprotein | 1 | 0 | 0 | 1 |
glucocerebrosidase | 1 | 0 | 0 | 1 |
aryl hydrocarbon receptor | 2 | 0 | 0 | 2 |
Caspase-7 | 1 | 0 | 0 | 1 |
potassium voltage-gated channel subfamily H member 2 isoform d | 1 | 0 | 0 | 1 |
caspase-3 | 1 | 0 | 0 | 1 |
importin subunit beta-1 isoform 1 | 2 | 0 | 0 | 2 |
snurportin-1 | 2 | 0 | 0 | 2 |
survival motor neuron protein isoform d | 3 | 0 | 0 | 3 |
cytochrome P450 3A4 isoform 1 | 2 | 0 | 0 | 2 |
Gamma-aminobutyric acid receptor subunit pi | 2 | 0 | 0 | 2 |
Gamma-aminobutyric acid receptor subunit beta-1 | 2 | 0 | 0 | 2 |
Gamma-aminobutyric acid receptor subunit delta | 2 | 0 | 0 | 2 |
Gamma-aminobutyric acid receptor subunit gamma-2 | 2 | 0 | 0 | 2 |
Gamma-aminobutyric acid receptor subunit alpha-5 | 2 | 0 | 0 | 2 |
Gamma-aminobutyric acid receptor subunit alpha-3 | 2 | 0 | 0 | 2 |
Gamma-aminobutyric acid receptor subunit gamma-1 | 2 | 0 | 0 | 2 |
Gamma-aminobutyric acid receptor subunit alpha-2 | 2 | 0 | 0 | 2 |
Gamma-aminobutyric acid receptor subunit alpha-4 | 2 | 0 | 0 | 2 |
Gamma-aminobutyric acid receptor subunit gamma-3 | 2 | 0 | 0 | 2 |
Gamma-aminobutyric acid receptor subunit alpha-6 | 2 | 0 | 0 | 2 |
Nuclear receptor ROR-gamma | 2 | 0 | 0 | 2 |
Spike glycoprotein | 3 | 0 | 0 | 3 |
Gamma-aminobutyric acid receptor subunit alpha-1 | 2 | 0 | 0 | 2 |
Gamma-aminobutyric acid receptor subunit beta-3 | 2 | 0 | 0 | 2 |
Gamma-aminobutyric acid receptor subunit beta-2 | 2 | 0 | 0 | 2 |
TAR DNA-binding protein 43 | 3 | 0 | 0 | 3 |
Large neutral amino acids transporter small subunit 1 | 0 | 1 | 0 | 1 |
GABA theta subunit | 2 | 0 | 0 | 2 |
Gamma-aminobutyric acid receptor subunit epsilon | 2 | 0 | 0 | 2 |
Chain B, DIHYDROFOLATE REDUCTASE | 0 | 0 | 1 | 1 |
Chain B, DIHYDROFOLATE REDUCTASE | 0 | 0 | 1 | 1 |
Chain B, DIHYDROFOLATE REDUCTASE | 0 | 0 | 1 | 1 |
Chain A, HADH2 protein | 2 | 0 | 0 | 2 |
Chain B, HADH2 protein | 2 | 0 | 0 | 2 |
Chain A, 2-oxoglutarate Oxygenase | 1 | 0 | 0 | 1 |
Chain A, Ferritin light chain | 2 | 0 | 0 | 2 |
acid sphingomyelinase | 1 | 0 | 0 | 1 |
dopamine D1 receptor | 1 | 0 | 0 | 1 |
ClpP | 1 | 0 | 0 | 1 |
ATAD5 protein, partial | 1 | 0 | 0 | 1 |
Microtubule-associated protein tau | 1 | 0 | 0 | 1 |
Thymidylate synthase | 0 | 1 | 0 | 1 |
alpha-galactosidase | 1 | 0 | 0 | 1 |
IDH1 | 1 | 0 | 0 | 1 |
Thymidylate synthase | 0 | 1 | 0 | 1 |
Bloom syndrome protein isoform 1 | 2 | 0 | 0 | 2 |
polyunsaturated fatty acid lipoxygenase ALOX12 | 1 | 0 | 0 | 1 |
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | 2 | 0 | 0 | 2 |
vitamin D3 receptor isoform VDRA | 4 | 0 | 0 | 4 |
transcriptional regulator ERG isoform 3 | 1 | 0 | 0 | 1 |
DNA polymerase beta | 1 | 0 | 0 | 1 |
flap endonuclease 1 | 1 | 0 | 0 | 1 |
DNA polymerase eta isoform 1 | 1 | 0 | 0 | 1 |
DNA polymerase kappa isoform 1 | 1 | 0 | 0 | 1 |
M-phase phosphoprotein 8 | 1 | 0 | 0 | 1 |
muscleblind-like protein 1 isoform 1 | 1 | 0 | 0 | 1 |
histone acetyltransferase KAT2A isoform 1 | 1 | 0 | 0 | 1 |
caspase-1 isoform alpha precursor | 1 | 0 | 0 | 1 |
Toll-like receptor 4 | 0 | 1 | 0 | 1 |
Fatty-acid amide hydrolase 1 | 0 | 1 | 0 | 1 |
Bile salt export pump | 0 | 1 | 0 | 1 |
ATP-binding cassette sub-family C member 3 | 0 | 1 | 0 | 2 |
Dihydrofolate reductase | 0 | 2 | 0 | 3 |
Dihydrofolate reductase | 0 | 2 | 0 | 3 |
Dihydrofolate reductase | 0 | 1 | 0 | 1 |
Dihydrofolate reductase | 0 | 1 | 0 | 1 |
Dihydrofolate reductase | 0 | 1 | 0 | 1 |
Dihydrofolate reductase | 0 | 2 | 0 | 3 |
Thymidylate synthase | 0 | 1 | 0 | 1 |
Carbonic anhydrase 2 | 0 | 0 | 1 | 1 |
Thymidylate synthase | 0 | 2 | 0 | 2 |
Bifunctional dihydrofolate reductase-thymidylate synthase | 0 | 1 | 0 | 1 |
5-hydroxytryptamine receptor 2C | 0 | 1 | 0 | 2 |
High mobility group protein B1 | 0 | 0 | 1 | 1 |
Dihydrofolate reductase | 0 | 1 | 0 | 1 |
Thymidylate synthase | 0 | 1 | 0 | 1 |
Dihydrofolate reductase | 0 | 2 | 2 | 4 |
Glucose-6-phosphate 1-dehydrogenase | 0 | 1 | 0 | 1 |
Bifunctional dihydrofolate reductase-thymidylate synthase | 0 | 1 | 0 | 1 |
Folate receptor beta | 0 | 1 | 0 | 1 |
5-hydroxytryptamine receptor 2A | 0 | 1 | 0 | 1 |
Cytochrome P450 11B1, mitochondrial | 0 | 1 | 0 | 1 |
Folate receptor alpha | 0 | 1 | 0 | 1 |
Dihydrofolate reductase | 0 | 2 | 0 | 2 |
Histidine decarboxylase | 0 | 1 | 0 | 1 |
Trifunctional purine biosynthetic protein adenosine-3 | 0 | 1 | 0 | 1 |
Cyclin-dependent kinase 2 | 0 | 0 | 1 | 1 |
Bifunctional purine biosynthesis protein ATIC | 0 | 2 | 0 | 2 |
Multidrug resistance-associated protein 1 | 0 | 0 | 0 | 1 |
Delta-type opioid receptor | 0 | 1 | 0 | 1 |
Mu-type opioid receptor | 0 | 1 | 0 | 1 |
Kappa-type opioid receptor | 0 | 1 | 0 | 1 |
Reduced folate transporter | 0 | 2 | 0 | 2 |
Folylpolyglutamate synthase, mitochondrial | 0 | 1 | 0 | 3 |
6-phosphogluconate dehydrogenase, decarboxylating | 0 | 1 | 0 | 1 |
Caspase-7 | 1 | 0 | 0 | 1 |
Solute carrier organic anion transporter family member 1A3 | 0 | 0 | 0 | 1 |
Dihydrofolate reductase | 0 | 1 | 0 | 1 |
Pteridine reductase 1 | 0 | 1 | 0 | 1 |
Folylpolyglutamate synthase, mitochondrial | 0 | 1 | 0 | 3 |
Bifunctional dihydrofolate reductase-thymidylate synthase | 0 | 1 | 0 | 1 |
Bifunctional dihydrofolate reductase-thymidylate synthase | 0 | 1 | 0 | 1 |
Solute carrier family 22 member 6 | 0 | 0 | 0 | 1 |
Canalicular multispecific organic anion transporter 1 | 0 | 1 | 0 | 2 |
Trifunctional purine biosynthetic protein adenosine-3 | 0 | 1 | 0 | 1 |
Solute carrier family 22 member 20 | 0 | 1 | 0 | 1 |
Dihydrofolate reductase | 0 | 1 | 0 | 1 |
Solute carrier family 22 member 8 | 0 | 0 | 0 | 1 |
Solute carrier family 22 member 6 | 0 | 1 | 0 | 1 |
Dihydrofolate reductase | 0 | 1 | 0 | 1 |
ATP-binding cassette sub-family C member 11 | 0 | 0 | 0 | 1 |
Proton-coupled folate transporter | 0 | 1 | 0 | 1 |
Multidrug resistance associated protein | 0 | 1 | 0 | 2 |
Solute carrier family 22 member 11 | 0 | 0 | 0 | 1 |
Protein-arginine deiminase type-4 | 0 | 1 | 0 | 1 |
Broad substrate specificity ATP-binding cassette transporter ABCG2 | 0 | 0 | 0 | 1 |
Programmed cell death protein 1 | 0 | 1 | 0 | 1 |
E3 ubiquitin-protein ligase ZFP91 | 0 | 0 | 0 | 1 |
Programmed cell death 1 ligand 1 | 0 | 1 | 0 | 1 |
pregnane X receptor | 2 | 0 | 0 | 2 |
nuclear receptor ROR-gamma isoform 1 | 2 | 0 | 0 | 2 |
Glucocorticoid receptor | 0 | 2 | 1 | 3 |
Glycine receptor subunit alpha-1 | 0 | 2 | 0 | 2 |
Glycine receptor subunit beta | 0 | 2 | 0 | 2 |
Glycine receptor subunit alpha-2 | 0 | 2 | 0 | 2 |
Glycine receptor subunit alpha-3 | 0 | 2 | 0 | 2 |
cytochrome P450 2C19 precursor | 1 | 0 | 0 | 1 |
lethal factor (plasmid) | 1 | 0 | 0 | 1 |
Glutamate 5-kinase | 0 | 0 | 0 | 1 |
Angiotensin-converting enzyme | 0 | 1 | 0 | 1 |
Neutral amino acid transporter A | 0 | 1 | 0 | 1 |
Neutral amino acid transporter B(0) | 0 | 1 | 0 | 1 |
Amino acid transporter | 0 | 1 | 0 | 1 |
nonstructural protein 1 | 1 | 0 | 0 | 1 |
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 1 | 0 | 0 | 1 |
heat shock protein HSP 90-alpha isoform 2 | 0 | 0 | 0 | 1 |
Polyunsaturated fatty acid lipoxygenase ALOX15B | 1 | 0 | 0 | 1 |
Histamine H2 receptor | 1 | 0 | 0 | 1 |
Guanine nucleotide-binding protein G | 1 | 0 | 0 | 1 |
heat shock protein 90, putative | 0 | 0 | 0 | 1 |
arylsulfatase A | 1 | 0 | 0 | 1 |
Prostaglandin G/H synthase 1 | 0 | 1 | 0 | 1 |
cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 0 | 1 | 0 | 1 |
Prostaglandin G/H synthase 2 | 0 | 1 | 0 | 1 |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 0 | 1 | 0 | 1 |
cAMP-specific 3',5'-cyclic phosphodiesterase 4C | 0 | 1 | 0 | 1 |
cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 0 | 1 | 0 | 1 |
Luciferase | 1 | 0 | 0 | 1 |
regulator of G-protein signaling 4 | 1 | 0 | 0 | 1 |
hemoglobin subunit beta | 1 | 0 | 0 | 1 |
serine/threonine-protein kinase PLK1 | 1 | 0 | 0 | 1 |
Cytochrome P450 2B1 | 0 | 1 | 0 | 1 |
Cytochrome P450 2B6 | 0 | 1 | 0 | 1 |
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |