Inhalation Injury, Smoke

Pulmonary injury following the breathing in of toxic smoke from burning materials such as plastics, synthetics, building materials, etc. This injury is the most frequent cause of death in burn patients.

Synonym
Smoke Inhalation Injury
Inhalation Injury, Smoke
Injury, Smoke Inhalation

Excerpt	Reference
"Smoke inhalation injury is a complex of disease processes best understood and treated when defined in terms of the time period after injury."	( Demling, RH, 1993)
"When smoke inhalation injury is combined with burn injury or pneumonia, the physiological responses are different and more severe than those of smoke inhalation injury alone."	( Murakami, K; Traber, DL, 2003)
"Smoke inhalation injury is a major cause of morbidity and mortality in thermally injured individuals."	( Enkhbaatar, P; Herndon, DN; Kikuchi, Y; Maybauer, DM; Maybauer, MO; Morita, N; Nishida, K; Traber, DL; Traber, LD; Westphal, M; Westphal-Varghese, BB, 2005)
"Smoke inhalation injury is often complicated with pneumonia, which frequently leads to subsequent development of sepsis."	( Enkhbaatar, P; Hamahata, A; Herndon, D; Jaroch, S; Jonkam, C; Lange, M; Nakano, Y; Traber, D; Traber, L; Wang, J, 2009)
"Smoke inhalation injury is a major comorbid factor in patients with thermal injury and occurs in about 30% of patients with major burns."	( Basaran, O; Belli, S; Haberal, M; Karabay, G; Karakayali, H; Kut, A; Ozdemir, BH; Türkoğlu, S, 2011)
"Smoke inhalation injury is the leading cause of acute respiratory failure in critical burn victims."	( Jin, Y; Lv, T; Qiu, X; Sun, Y; Wang, J; Xia, Z; Zhu, F, 2012)
"Smoke inhalation injury is associated with significant morbidity and mortality."	( Chatzivasiloglou, F; Katsenos, S; Psara, A; Tsintiris, K, 2016)
"Smoke inhalation injury is common in victims of domestic fires, among whom children are the most vulnerable."	( Geslain, G; Heraut, F; Rubinsztajn, R; Tilea, B, 2020)

Excerpt	Reference
"Recent studies on smoke inhalation injury have been focused on nitric oxide (NO) as an essential factor of progressive lung injury."	( McGuire, R; Salzman, A; Snyder, N; Soejima, K; Szabó, C; Traber, DL; Traber, LD; Uchida, T, 2000)

Excerpt	Reference
"Smoke inhalation injury affects nearly one third of all major burn victims."	( Lee-Chiong, TL; Matthay, RA, 1995)

Excerpt	Reference
"After administration of a severe smoke inhalation injury, the piglets were randomly assigned to either the perfluorocarbon or control groups."	( Cioffi, WG; Fitzpatrick, JC; Jordan, BS; Pruitt, BA; Salman, N; Williams, J, 1997)
"Based on all parameters tested, smoke inhalation injury was reduced by prophylactic aadministration of HBO2."	( Fisher, D; Mendiguren, I; Thom, SR, 2001)
"Advances in the treatment of smoke inhalation injury have been limited in the past years."	( Jin, Y; Lv, T; Qiu, X; Sun, Y; Wang, J; Xia, Z; Zhu, F, 2012)
"Food and Drug Administration (FDA) for smoke inhalation injury with or without concurrent burn injury."	( Kibbe, MR; Maile, R; Mercel, A; Tsihlis, ND, 2020)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	22 (4.58)	23.3326
1990's	123 (25.63)	12.5806
2000's	150 (31.25)	18.1394
2010's	160 (33.33)	28.8240
2020's	25 (5.21)	9.53

Drug	Relationship Strength	Studies	Trials
2,3-diphosphoglycerate	low	1	0
acetaldehyde	low	1	0
ammonium hydroxide	low	1	0
benzene	low	2	0
1-butanol	low	1	0
carbon monoxide	medium	40	1
methane	low	1	0
chlorine	low	10	0
hydrochloric acid	low	4	0
salicylic acid	low	1	0
hydrogen sulfide	low	2	0
lactic acid	low	4	0
dimethyl sulfoxide	low	2	0
formaldehyde	low	3	0
hydrogen cyanide	medium	31	2
hydrogen	low	1	0
methanol	medium	41	1
naphthalene	low	2	0
nitrates	medium	12	1
nitrites	medium	11	1
phosphorylcholine	low	1	0
1-propanol	low	1	0
pteridines	low	1	0
thiosulfates	low	6	0
sulfur dioxide	low	1	0
toluene	low	1	0
1-anilino-8-naphthalenesulfonate	low	1	0
2,4-dinitrophenol	low	1	0
4-aminopyridine	low	1	0
phenytoin	low	1	0
7-nitroindazole	low	5	0
acetazolamide	low	1	0
albuterol	low	7	0
pimagedine	low	1	0
theophylline	low	2	0
benzo(a)pyrene	low	1	0
chloroquine	low	1	0
ciprofloxacin	low	1	0
deferoxamine	low	3	0
valproic acid	low	1	0
furegrelate	low	1	0
gabexate	low	1	0
gentamicin	medium	2	1
guaifenesin	low	4	0
ibuprofen	low	2	0
indomethacin	low	2	0
isoproterenol	low	1	0
ketorolac	low	1	0
edaravone	low	1	0
mebendazole	low	2	0
meprobamate	low	1	0
2-mercaptoethylguanidine	low	3	0
methylphenidate	low	1	0
pentoxifylline	low	4	0
probucol	low	1	0
zinc chloride	low	9	0
prednisolone	low	1	0
alloxan	low	1	0
piperonyl butoxide	low	1	0
hydroxyproline	low	3	0
prednisone	low	2	0
glutamine	low	1	0
cyanides	medium	50	1
carbostyril	low	1	0
phenylephrine	low	1	0
edetic acid	low	1	0
tyrosine	low	12	0
methicillin	low	1	0
methylene blue	low	1	0
leucine	low	1	0
phenylalanine	low	1	0
hexachloroethane	low	5	0
mannitol	low	1	0
n-pentanol	low	1	0
arginine	low	2	0
ethane	low	5	0
ethylene	low	1	0
propane	low	1	0
vinyl chloride	low	1	0
phosgene	low	2	0
phencyclidine	low	7	0
isobutyl alcohol	low	1	0
2-butanol	low	1	0
methylethyl ketone	low	1	0
trichloroethylene	low	1	0
methylprednisolone	low	3	0
butane	low	1	0
acrolein	low	5	0
pyrazolanthrone	low	1	0
2-naphthol	low	1	0
catechin	low	1	0
quinazolines	low	1	0
indazoles	low	5	0
thiocyanate	low	1	0
perfluorodecalin	low	1	0
n-pentyl nitrite	low	1	0
cepharanthine	low	1	0
carvacrol	low	1	0
methamphetamine	low	2	0
malondialdehyde	low	19	0
acetylcysteine	low	9	0
1-phenylazo-2-naphthol	low	1	0
4-dimethylaminopyridine	low	1	0
zinc oxide	low	2	0
hydrofluoric acid	low	2	0
vancomycin	low	1	0
d-alpha tocopherol	low	5	0
paraquat	low	1	0
dronabinol	low	1	0
chloric acid	low	1	0
neodymium	low	1	0
titanium	low	1	0
cadmium	low	1	0
xenon	medium	1	1
yttrium	low	1	0
chromates	low	1	0
sodium thiosulfate	low	5	0
chlorine	low	1	0
vasotocin	low	1	0
ozone	low	1	0
titanium dioxide	low	1	0
zinc chromate	low	1	0
cetylpyridinium chloride anhydrous	low	1	0
isopentyl alcohol	low	1	0
calcium oxalate	low	1	0
glutamic acid	low	1	0
cefazolin	low	1	0
substance p	low	2	0
dobutamine	low	1	0
ng-nitroarginine methyl ester	low	2	0
piperacillin	low	1	0
bw-755c	low	2	0
sulotroban	low	1	0
fomesafen	low	2	0
simvastatin	low	2	0
adenosine	low	1	0
anisodamine	low	1	0
atrinositol	low	1	0
delphinidin	low	1	0
fluorodeoxyglucose f18	low	2	0
sertraline	low	2	0
tetrandrine	low	1	0
cobalt-ethylenediamine tetraacetic acid chelate	low	1	0
gamma-tocopherol	low	4	0
chlorates	low	1	0
cp 96345	low	2	0
sr 48968	low	1	0
fpl 55712	low	1	0
s-ethyl glutathione	low	1	0
cv 3988	low	2	0
1-hexadecyl-2-acetyl-glycero-3-phosphocholine	low	2	0
thromboxanes	low	1	0
peroxynitrous acid	low	5	0
tezosentan	low	1	0
borneo	low	1	0
hydroxyl radical	low	2	0
dipalmitoylphosphatidylcholine, hexadecanol, tyloxapol drug combination	low	1	0
technetium tc 99m pentetate	low	1	0
organophosphonates	low	1	0
3-nitrotyrosine	low	12	0
sodium sulfide	low	1	0
benzofurans	low	1	0
glycogen	low	2	0
fibrin	low	1	0
elastin	low	1	0
tretinoin	low	1	0
arachidonic acid	low	1	0
oleic acid	low	1	0
cocaine	low	1	0
benzoylecgonine	low	1	0
lisofylline	low	2	0
bromochloroacetic acid	low	1	0
phenyl-n-tert-butylnitrone	low	1	0
arginine vasopressin	low	2	0
capsaicin	low	1	0
1,3-dimethylthiourea	low	1	0
thiourea	low	1	0
D-fructopyranose	low	1	0
tamoxifen	low	1	0
nadp	low	1	0
nitrogen dioxide	low	4	0
bilirubin	low	1	0
dinoprostone	low	1	0
dinoprost	low	2	0
beta carotene	low	1	0
leukotriene b4	low	1	0
thromboxane a2	low	1	0
leukotriene e4	low	1	0
6-ketoprostaglandin f1 alpha	low	2	0
prostaglandin f1	low	1	0
pulmicort	low	1	0
humulene	low	1	0
tranilast	low	1	0
8-epi-prostaglandin f2alpha	low	1	0
ozagrel	low	1	0
thromboxane b2	low	5	0
phenylephrine hydrochloride	low	4	0
topiramate	low	1	0
morphine	low	2	0
casticin	low	1	0
lead	medium	1	1
sulfur	low	1	0
puerarin	low	1	0
tiotropium bromide	low	2	0
oxalates	low	2	0
u 75412e	low	3	0
beta-escin	low	2	0
mocetinostat	low	22	0
aluminum oxide	low	1	0
technetium tc 99m exametazime	medium	1	1
cytochrome c-t	low	1	0
atrial natriuretic factor	low	1	0
phosphatidylcholines	low	2	0
sodium nitrite	low	5	0
cortisol succinate, sodium salt	low	1	0
chiniofon	low	1	0
piperidines	low	1	0
interleukin-8	low	17	0
hydroxocobalamin	medium	45	2
natriuretic peptide, brain	low	1	0
ascorbic acid	low	3	0
epidermal growth factor	low	2	0
calca protein, human	low	3	0
transforming growth factor beta	low	1	0
cyclin d1	low	1	0
cobinamide	low	1	0
bacoside a	low	2	0
vitamin b 12	low	1	0
asbestos, amosite	low	1	0
muramidase	low	1	0
exudates	low	1	0
cyclic gmp	low	3	0
allopurinol	low	2	0
phenanthrenes	low	1	0

Protein Targets (1,401)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain B, pheromone binding protein	0	0	1	1
Chain A, pheromone binding protein	0	0	1	1
Chain A, JmjC domain-containing histone demethylation protein 3A	12	0	0	12
Chain A, RNA-directed RNA polymerase NS5	0	1	0	1
acid sphingomyelinase	3	0	0	3
thioredoxin reductase	28	0	0	28
USP1 protein, partial	21	0	0	21
TDP1 protein	40	0	0	40
vitamin D3 receptor isoform VDRA	19	0	0	19
importin subunit beta-1 isoform 1	5	0	0	5
flap endonuclease 1	19	0	0	19
serine/threonine-protein kinase PLK1	3	0	0	3
snurportin-1	5	0	0	5
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	6	0	0	6
GTP-binding nuclear protein Ran isoform 1	4	0	0	4
DNA polymerase eta isoform 1	4	0	0	4
DNA polymerase iota isoform a (long)	13	0	0	13
urokinase-type plasminogen activator precursor	8	0	0	8
plasminogen precursor	8	0	0	8
urokinase plasminogen activator surface receptor precursor	8	0	0	8
geminin	40	0	0	40
DNA polymerase kappa isoform 1	13	0	0	13
fibroblast growth factor 22 isoform 1 precursor	0	0	0	1
Mitogen-activated protein kinase 13	0	1	0	1
Beta-lactamase	0	1	0	1
Transthyretin	0	0	1	1
Fatty acid-binding protein, intestinal	0	3	2	5
Fatty acid-binding protein, adipocyte	0	4	2	6
Cyclin-A2	0	2	0	2
Cannabinoid receptor 1	0	3	2	5
Cyclin-dependent kinase 2	0	2	2	4
Choline O-acetyltransferase	0	1	0	1
Mitogen-activated protein kinase 12	0	1	1	2
Guanine nucleotide-binding protein G	8	0	0	8
Fatty acid-binding protein 5	0	2	1	3
Fatty acid-binding protein 5	0	0	2	2
Mitogen-activated protein kinase 11	0	1	0	1
Mitogen-activated protein kinase 14	0	2	0	2
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	23	0	0	23
aldehyde dehydrogenase 1 family, member A1	27	0	0	27
glucocorticoid receptor [Homo sapiens]	40	0	0	40
farnesoid X nuclear receptor	19	0	0	19
estrogen nuclear receptor alpha	59	0	0	59
Voltage-dependent calcium channel gamma-2 subunit	21	0	0	21
Cellular tumor antigen p53	40	0	0	40
Glutamate receptor 2	21	2	2	25
Choline O-acetyltransferase	0	2	0	3
Chain A, Cruzipain	12	0	0	12
regulator of G-protein signaling 4	16	0	0	16
Platelet-activating factor receptor	0	3	0	3
Inositol monophosphatase 1	9	0	0	9
Luciferase	17	0	0	17
RAR-related orphan receptor gamma	35	0	0	35
SMAD family member 2	14	0	0	14
SMAD family member 3	14	0	0	14
GLI family zinc finger 3	38	0	0	38
AR protein	48	0	0	48
estrogen receptor 2 (ER beta)	25	0	0	25
nuclear receptor subfamily 1, group I, member 3	25	0	0	25
progesterone receptor	26	0	0	26
retinoic acid nuclear receptor alpha variant 1	39	0	0	39
retinoid X nuclear receptor alpha	34	0	0	34
estrogen-related nuclear receptor alpha	46	0	0	46
pregnane X nuclear receptor	25	0	0	25
peroxisome proliferator activated receptor gamma	23	0	0	23
vitamin D (1,25- dihydroxyvitamin D3) receptor	25	0	0	25
aryl hydrocarbon receptor	20	0	0	20
activating transcription factor 6	18	0	0	18
v-jun sarcoma virus 17 oncogene homolog (avian)	19	0	0	19
thyroid hormone receptor beta isoform a	12	0	0	12
thyroid hormone receptor beta isoform 2	34	0	0	34
histone deacetylase 9 isoform 3	4	0	0	4
nuclear factor erythroid 2-related factor 2 isoform 1	43	0	0	43
hypoxia-inducible factor 1 alpha subunit	17	0	0	17
thyroid stimulating hormone receptor	22	0	0	22
peroxisome proliferator-activated receptor delta	19	0	0	19
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	23	0	0	23
Histone H2A.x	15	0	0	15
DNA repair and recombination protein RadA	0	0	2	2
Cytochrome P450 1A2	0	6	1	7
Cytochrome P450 2A6	0	4	0	4
Sulfotransferase 1A1	0	0	0	1
Cytochrome P450 2A5	0	2	0	2
Sulfotransferase 1E1	0	0	0	1
Sulfotransferase 1A1	0	0	0	1
Sulfotransferase 2A1	0	0	0	1
acetylcholinesterase	13	0	0	13
pregnane X receptor	8	0	0	8
67.9K protein	10	0	0	10
cellular tumor antigen p53 isoform a	7	0	0	7
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	10	0	0	10
nuclear factor erythroid 2-related factor 2 isoform 2	14	0	0	14
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	7	0	0	7
mitogen-activated protein kinase 1	9	0	0	9
nuclear receptor ROR-gamma isoform 1	18	0	0	18
survival motor neuron protein isoform d	19	0	0	19
histone acetyltransferase KAT2A isoform 1	10	0	0	10
Integrin beta-3	5	0	1	6
Integrin alpha-IIb	5	0	1	6
Nuclear receptor ROR-gamma	12	1	1	14
TAR DNA-binding protein 43	8	0	0	8
ATPase family AAA domain-containing protein 5	15	0	0	15
Ataxin-2	21	0	0	21
Chain A, Putative fructose-1,6-bisphosphate aldolase	9	0	0	9
phosphopantetheinyl transferase	17	0	0	17
bromodomain adjacent to zinc finger domain 2B	9	0	0	9
euchromatic histone-lysine N-methyltransferase 2	36	0	0	36
pyruvate kinase PKM isoform a	2	0	0	2
Glycoprotein hormones alpha chain	2	0	0	2
Tubulin--tyrosine ligase	0	2	0	2
Microtubule-associated protein tau	22	0	0	22
cytochrome P450 family 3 subfamily A polypeptide 4	22	0	0	22
cytochrome P450 2D6	13	0	0	13
glucocerebrosidase	8	0	0	8
IDH1	17	0	0	17
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	16	0	0	16
cytochrome P450 2D6 isoform 1	5	0	0	5
chromobox protein homolog 1	19	0	0	19
transcriptional regulator ERG isoform 3	6	0	0	6
peripheral myelin protein 22	20	0	0	20
lethal factor (plasmid)	13	0	0	13
lamin isoform A-delta10	25	0	0	25
Potassium channel subfamily K member 2	0	0	2	2
Rap guanine nucleotide exchange factor 3	7	0	0	7
Potassium voltage-gated channel subfamily A member 3	0	0	1	1
Acetylcholinesterase	0	1	0	1
Pteridine reductase 1	0	1	0	1
Potassium voltage-gated channel subfamily A member 1	0	2	0	2
Potassium voltage-gated channel subfamily H member 2	0	14	0	15
ATP-dependent phosphofructokinase	18	0	0	18
Choline kinase alpha	0	0	1	1
Solute carrier organic anion transporter family member 2A1	0	1	0	6
Chain A, HADH2 protein	12	0	0	12
Chain B, HADH2 protein	12	0	0	12
endonuclease IV	5	0	0	5
Bloom syndrome protein isoform 1	16	0	0	16
cytochrome P450 2C19 precursor	3	0	0	3
muscleblind-like protein 1 isoform 1	7	0	0	7
muscarinic acetylcholine receptor M1	7	0	0	7
neuropeptide S receptor isoform A	5	0	0	5
Aromatase	0	3	0	3
Amine oxidase [flavin-containing] A	0	1	0	1
Nitric oxide synthase, endothelial	0	2	0	4
Nitric oxide synthase, endothelial	0	3	0	4
Nitric oxide synthase, brain	0	5	0	7
Nitric oxide synthase, brain	0	1	0	2
Nitric oxide synthase, inducible	0	4	0	5
Nitric oxide synthase, inducible	0	3	1	7
Nitric oxide synthase, endothelial	0	1	0	1
caspase 7, apoptosis-related cysteine protease	8	0	0	8
caspase-3	8	0	0	8
thyroid stimulating hormone receptor	14	0	0	14
thyrotropin-releasing hormone receptor	4	0	0	4
Caspase-7	3	0	0	3
caspase-3	3	0	0	3
heat shock protein beta-1	13	0	0	13
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	16	0	0	16
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Beta-lactamase	11	0	0	11
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Class Iii Chitinase Chia1	0	1	0	1
Chain A, Carbonic anhydrase 13	0	1	0	1
Chain A, Carbonic anhydrase II	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase	0	1	0	1
Chain B, Carbonic anhydrase	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	3	0	3
GALC protein	5	0	0	5
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	6	0	6
arylsulfatase A	16	0	0	16
Carbonic anhydrase	0	6	0	6
Gamma-aminobutyric acid receptor subunit pi	11	5	1	17
ATP-binding cassette sub-family C member 3	0	18	0	18
Multidrug resistance-associated protein 4	0	18	0	21
Carbonic anhydrase	0	2	0	2
Solute carrier family 22 member 6	0	6	0	6
Carbonic anhydrase 12	0	6	1	12
Prolyl endopeptidase	0	2	0	2
Carbonic anhydrase-related protein 11	0	1	0	3
Bile salt export pump	0	33	0	33
Glycogen phosphorylase, muscle form	0	1	0	1
Renin	0	4	0	4
Carbonic anhydrase 1	0	22	1	32
Carbonic anhydrase 2	0	22	2	32
Carbonic anhydrase 2	0	2	0	2
Carbonic anhydrase 3	0	6	1	11
Cathepsin B	0	1	0	1
Cytochrome P450 3A4	0	8	3	12
Steryl-sulfatase	0	1	0	1
5-hydroxytryptamine receptor 2C	0	3	0	3
Polyunsaturated fatty acid 5-lipoxygenase	0	5	1	6
Cytochrome P450 2C8	0	2	0	2
Cytochrome P450 2D6	0	4	1	5
Cytochrome P450 2C9	0	8	1	9
5-hydroxytryptamine receptor 2A	0	4	0	4
Androgen receptor	0	8	0	8
Gamma-aminobutyric acid receptor subunit beta-1	11	5	1	17
Translocator protein	0	1	2	3
Gamma-aminobutyric acid receptor subunit delta	11	5	1	17
Gamma-aminobutyric acid receptor subunit gamma-2	11	5	1	17
Gamma-aminobutyric acid receptor subunit alpha-5	11	5	1	17
Gamma-aminobutyric acid receptor subunit alpha-3	11	5	1	17
Arachidonate 5-lipoxygenase-activating protein	0	2	0	2
Cytochrome P450 2B6	0	3	0	3
Carbonic anhydrase 4	0	19	1	24
Carbonic anhydrase 6	0	11	1	16
Gamma-aminobutyric acid receptor subunit gamma-1	11	5	1	17
Gamma-aminobutyric acid receptor subunit alpha-2	11	5	1	17
Carbonic anhydrase 5A, mitochondrial	0	2	0	2
Adenosine receptor A1	0	7	1	11
Serum paraoxonase/arylesterase 1	0	2	0	2
Dipeptidyl peptidase 4	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	11	5	1	17
Gamma-aminobutyric acid receptor subunit gamma-3	11	5	1	17
Endochitinase	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	11	5	1	17
Adenosine receptor A2a	0	6	1	11
5-hydroxytryptamine receptor 2B	0	3	0	3
Sodium-dependent serotonin transporter	0	8	0	9
Delta-type opioid receptor	0	3	0	5
Cytochrome P450 2C19	0	5	1	6
Delta-type opioid receptor	0	4	2	7
Mu-type opioid receptor	0	5	1	9
Carbonic anhydrase 5A, mitochondrial	0	12	2	19
Carbonic anhydrase	0	12	0	14
Kappa-type opioid receptor	0	3	0	4
Carbonic anhydrase 7	0	10	1	15
Carbonic anhydrase	0	1	0	1
D(1A) dopamine receptor	3	1	0	4
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Carbonic anhydrase	0	2	0	4
D(2) dopamine receptor	0	4	2	6
Gamma-aminobutyric acid receptor subunit alpha-1	11	5	1	17
Gamma-aminobutyric acid receptor subunit beta-3	11	5	1	17
Gamma-aminobutyric acid receptor subunit beta-2	11	5	1	17
Cholinesterase	0	2	0	2
Carbonic anhydrase	0	2	0	2
Mu-type opioid receptor	0	5	0	5
Fatty-acid amide hydrolase 1	0	5	0	5
Beta-carbonic anhydrase 1	0	2	0	2
Carbonic anhydrase 2	0	2	0	2
Glutamate receptor ionotropic, NMDA 2B	0	7	2	11
Squalene synthase	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	2	0	2
Carbonic anhydrase 9	0	11	1	17
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase, alpha family	0	4	0	4
Carbonic anhydrase	0	2	0	4
Carbonic anhydrase 3	0	2	0	2
Carbonic anhydrase	0	6	0	9
Carbonic anhydrase	0	2	0	5
Carbonic anhydrase	0	2	0	2
Sigma intracellular receptor 2	0	3	0	3
Delta carbonic anhydrase	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	4	0	4
Renin	0	1	0	1
Carbonic anhydrase	0	2	0	4
Endochitinase A1	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	1
Carbonic anhydrase 13	0	5	1	8
GABA theta subunit	11	5	1	17
Canalicular multispecific organic anion transporter 1	0	18	0	18
Carbonic anhydrase 4	0	4	0	4
Carbonic anhydrase 15	0	10	0	13
Acidic mammalian chitinase	0	1	0	1
Carbonic anhydrase 13	0	8	0	11
Carbonic anhydrase 7	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	11	5	1	17
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase 14	0	6	1	12
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 2, isoform A	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	10	1	16
Chain A, 2-oxoglutarate Oxygenase	17	0	0	17
Chain A, ATP-DEPENDENT DNA HELICASE Q1	6	0	0	6
dopamine D1 receptor	5	0	0	5
15-lipoxygenase, partial	6	0	0	6
NFKB1 protein, partial	8	0	0	8
Thrombopoietin	4	0	0	4
D(1A) dopamine receptor	6	0	0	6
Histone deacetylase 3	0	5	0	5
Histone deacetylase 4	0	4	0	4
Histone deacetylase 1	0	5	0	5
Histone deacetylase 7	0	4	0	4
Histone deacetylase 2	0	5	0	5
Polyamine deacetylase HDAC10	0	3	0	3
Histone deacetylase 11	0	4	0	4
Histone deacetylase 8	0	4	0	4
Histone deacetylase 6	0	4	0	4
Histone deacetylase 9	0	3	0	3
Histone deacetylase 5	0	4	0	4
Transient receptor potential cation channel subfamily A member 1	0	1	2	4
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain B, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, tRNA (guanine-N(1)-)-methyltransferase	0	0	1	1
Chain A, Uncharacterized protein MJ0883	0	0	1	1
signal transducer and activator of transcription 6, interleukin-4 induced	1	0	0	1
NPYLR7B	0	0	3	3
glycogen synthase kinase-3 beta isoform 1	0	0	1	1
high affinity choline transporter 1 isoform a	0	1	0	1
Sodium/nucleoside cotransporter 1	0	2	0	2
Calcium dependent protein kinase	0	1	0	1
Mitogen-activated protein kinase kinase kinase 7	0	0	1	1
Sodium/nucleoside cotransporter 2	0	2	0	2
Purine nucleoside phosphorylase	0	1	0	1
Epidermal growth factor receptor	0	7	0	7
Phosphoglycerate kinase 1	0	1	0	1
Adenosine deaminase	0	0	0	1
Avidin	0	0	1	1
Adenosine deaminase	0	0	0	1
Glyceraldehyde-3-phosphate dehydrogenase	0	2	0	2
Receptor tyrosine-protein kinase erbB-2	0	3	0	3
Insulin receptor	0	0	0	1
Phosphoglycerate kinase 2	0	1	0	1
Heat shock protein HSP 90-alpha	0	1	2	3
Platelet-derived growth factor receptor beta	0	0	0	1
Adenosine receptor A3	0	7	2	10
Heat shock 70 kDa protein 1A	0	1	0	1
Heat shock cognate 71 kDa protein	0	0	1	1
Fibroblast growth factor receptor 1	0	0	0	1
Inosine-5'-monophosphate dehydrogenase 2	0	1	0	1
Endoplasmin	0	1	1	2
Inosine-5'-monophosphate dehydrogenase 1	0	1	0	1
Fibroblast growth factor receptor 2	0	0	0	1
Fibroblast growth factor receptor 4	0	0	0	1
Fibroblast growth factor receptor 3	0	0	0	1
Streptavidin	0	0	1	1
Adenosylhomocysteinase	0	0	0	1
Adenosine receptor A3	0	2	0	2
Adenosine receptor A2a	0	5	5	12
Adenosine receptor A2b	0	2	1	5
Adenosine receptor A2b	0	2	1	4
Adenylate kinase 2, mitochondrial	0	1	0	1
Adenosine receptor A1	0	6	3	12
Adenylate kinase isoenzyme 1	0	1	0	1
Phosphatidylinositol 4-kinase alpha	0	2	0	3
Adenosine receptor A1	0	1	1	2
Adenosine kinase	0	0	0	1
Adenosine deaminase	0	0	0	1
Equilibrative nucleoside transporter 2	0	2	0	2
Phosphatidylinositol 4-kinase type 2-beta	0	2	0	3
Histone-lysine N-methyltransferase, H3 lysine-79 specific	0	1	0	1
Equilibrative nucleoside transporter 1	0	2	0	2
Phosphatidylinositol 4-kinase type 2-alpha	0	2	0	3
Solute carrier family 28 member 3	0	2	0	2
Adenosine kinase	0	1	0	2
Phosphatidylinositol 4-kinase beta	0	2	0	3
5-methylthioadenosine/S-adenosylhomocysteine deaminase	0	0	0	1
Adenosine transporter 1	0	0	0	1
glp-1 receptor, partial	13	0	0	13
GLS protein	15	0	0	15
Beta-2 adrenergic receptor	0	6	5	12
Beta-1 adrenergic receptor	0	6	4	10
60 kDa chaperonin	0	3	0	3
60 kDa heat shock protein, mitochondrial	0	4	0	4
Beta-3 adrenergic receptor	0	3	3	6
10 kDa heat shock protein, mitochondrial	0	4	0	4
Thiosulfate sulfurtransferase	0	4	0	4
Beta-2 adrenergic receptor	0	1	2	5
60 kDa chaperonin	0	4	0	4
10 kDa chaperonin	0	4	0	4
Beta-2 adrenergic receptor	0	2	4	6
interleukin 8	3	0	0	3
ras-related protein Rab-9A	7	0	0	7
Polyphenol oxidase 2	0	4	0	6
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	1
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase	0	1	0	1
Xanthine dehydrogenase/oxidase	0	3	0	3
Nuclear receptor ROR-gamma	0	1	0	1
Xanthine dehydrogenase/oxidase	0	3	1	5
Purine nucleoside phosphorylase	0	0	1	1
Shiga toxin subunit A	0	1	0	1
Histamine H3 receptor	0	1	0	2
Chain A, Xcogt	0	0	1	1
Chain A, Xcogt	0	0	1	1
Chain A, Xcogt	0	0	1	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	5	0	0	5
Disintegrin and metalloproteinase domain-containing protein 17	4	0	0	4
Atrial natriuretic peptide receptor 3	0	1	0	1
Type-1A angiotensin II receptor	0	2	1	3
Type-1 angiotensin II receptor	0	0	1	1
Type-1B angiotensin II receptor	0	2	0	2
Type-1 angiotensin II receptor	0	2	2	4
Type-2 angiotensin II receptor	0	2	0	2
Type-2 angiotensin II receptor	0	2	0	2
Chain A, ADIPOCYTE LIPID-BINDING PROTEIN	0	0	1	1
Chain A, SERUM ALBUMIN	0	0	2	2
Chain A, SERUM ALBUMIN	0	0	2	2
thioredoxin glutathione reductase	5	0	0	5
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	7	0	0	7
lethal(3)malignant brain tumor-like protein 1 isoform I	3	0	0	3
cytochrome P450 3A4 isoform 1	11	0	0	11
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	3	0	0	3
caspase-1 isoform alpha precursor	4	0	0	4
Fatty-acid amide hydrolase 1	0	4	0	4
Polyunsaturated fatty acid lipoxygenase ALOX15B	7	0	0	7
Prostaglandin G/H synthase 1	0	5	0	7
Trypsin	0	2	0	2
Coagulation factor VII	0	2	0	2
Tissue factor	0	3	0	3
Prostaglandin G/H synthase 2	0	10	2	13
Nuclear receptor subfamily 4 group A member 2	0	0	4	4
Histamine H2 receptor	12	0	1	13
Calmodulin	0	0	0	1
Prostaglandin G/H synthase 2	0	6	0	7
Lanosterol 14-alpha demethylase	0	1	0	1
Solute carrier organic anion transporter family member 1B3	0	8	0	9
Cytosolic phospholipase A2 gamma	0	2	0	2
Transient receptor potential cation channel subfamily V member 2	0	2	1	3
Solute carrier organic anion transporter family member 1B1	0	9	0	10
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
alpha-galactosidase	2	0	0	2
Cationic amino acid transporter 3	0	1	0	1
Vasopressin V2 receptor	0	2	1	4
Oxytocin receptor	0	1	1	2
Vasopressin V1a receptor	0	0	3	3
Vasopressin V1a receptor	0	1	1	2
Vasopressin V1b receptor	0	1	1	2
Vasopressin V2 receptor	0	0	1	1
Vasopressin V1b receptor	0	1	1	3
Translocator protein	0	1	0	2
Oxytocin receptor	0	1	1	2
Vasopressin V2 receptor	0	1	1	2
Chain A, Hyaluronidase, phage associated	0	1	0	1
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	2	1	4
Urease	0	3	0	4
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	1	0	1
Alpha-2B adrenergic receptor	0	8	1	9
Spike glycoprotein	14	1	2	17
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
Atrial natriuretic peptide receptor 1	0	1	1	2
Atrial natriuretic peptide receptor 1	0	0	1	1
Chain A, Integrase	0	1	0	1
Chain A, Integrase	0	1	0	1
Chain A, T4 LYSOZYME	0	0	1	1
Chain A, GCN4P1	0	0	1	1
Chain B, GCN4P1	0	0	1	1
Chain C, GCN4P1	0	0	1	1
Chain A, T4 LYSOZYME	0	0	1	1
Chain A, T4 LYSOZYME	0	0	1	1
Chain A, Replicase polyprotein 1ab	0	1	0	1
Chain A, 3C-like proteinase	0	1	0	1
Endolysin	0	0	2	2
Smad3	7	0	0	7
apical membrane antigen 1, AMA1	5	0	0	5
DNA dC->dU-editing enzyme APOBEC-3F isoform a	1	0	0	1
Tyrosine-protein kinase Fyn	0	3	0	3
Amine oxidase [flavin-containing] A	0	2	0	2
Acetylcholinesterase	0	7	0	7
Aryl hydrocarbon receptor	0	0	1	1
core protein, partial	0	1	0	1
Caspase-7	2	0	0	2
Angiotensin-converting enzyme	0	1	0	2
B2 bradykinin receptor	0	1	0	1
B2 bradykinin receptor	0	4	1	7
B1 bradykinin receptor	0	1	0	1
Olfactory receptor 51E2	0	0	1	1
Polyunsaturated fatty acid 5-lipoxygenase	0	4	0	7
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Prostaglandin G/H synthase 1	0	11	0	11
Sodium- and chloride-dependent GABA transporter 1	0	3	0	3
Sodium- and chloride-dependent GABA transporter 2	0	3	0	3
Sodium- and chloride-dependent GABA transporter 3	0	3	0	3
Prostaglandin G/H synthase 2	0	3	0	5
Sodium- and chloride-dependent betaine transporter	0	3	0	3
Leukotriene B4 receptor 1	0	3	1	4
Prostaglandin G/H synthase 1	0	3	0	5
Leukotriene B4 receptor 2	0	2	1	3
transient receptor potential cation channel subfamily V member 1	1	0	0	1
Transient receptor potential cation channel subfamily V member 1	0	2	1	3
Lysine-specific histone demethylase 1A	0	1	0	1
NADH-ubiquinone oxidoreductase chain 1	0	1	0	1
Cannabinoid receptor 1	0	3	1	5
Cannabinoid receptor 2	0	3	1	5
Corticotropin-releasing factor receptor 2	0	1	0	1
Transient receptor potential cation channel subfamily V member 1	0	2	1	4
Transient receptor potential cation channel subfamily V member 4	0	0	1	1
Chain A, serum paraoxonase	0	1	0	1
Neutrophil cytosol factor 1	0	1	0	1
Poly [ADP-ribose] polymerase tankyrase-2	0	1	0	1
Acetylcholinesterase	0	2	0	2
UDP-glucuronosyltransferase 1A4	0	0	0	2
Secreted chorismate mutase	0	1	0	1
peripheral myelin protein 22 isoform 1	8	0	0	8
DNA polymerase beta	3	0	0	3
Arginase	0	2	0	2
Pancreatic triacylglycerol lipase	0	1	0	1
Prothrombin	0	1	2	3
Prostaglandin G/H synthase 1	0	4	1	6
Aldo-keto reductase family 1 member B1	0	11	0	11
Sucrase-isomaltase, intestinal	0	1	0	1
Mu-type opioid receptor	0	4	1	7
Delta-type opioid receptor	0	4	1	7
Kappa-type opioid receptor	0	4	1	7
Melatonin receptor type 1A	0	0	1	1
Melatonin receptor type 1B	0	0	1	1
Death-associated protein kinase 1	0	1	0	1
Beta-secretase 1	0	2	0	2
Dihydroorotate dehydrogenase	0	1	0	1
Solute carrier family 15 member 1	0	2	0	2
Solute carrier family 22 member 6	0	4	0	6
Solute carrier family 22 member 8	0	4	0	6
Solute carrier family 22 member 11	0	1	0	3
Solute carrier family 22 member 8	0	1	0	1
Fumarate hydratase	6	0	0	6
G	14	0	0	14
polyprotein	6	0	0	6
nuclear receptor subfamily 1, group I, member 2	6	0	0	6
NPC intracellular cholesterol transporter 1 precursor	6	0	0	6
potassium voltage-gated channel subfamily H member 2 isoform d	8	0	0	8
Interferon beta	20	0	0	20
HLA class I histocompatibility antigen, B alpha chain	14	0	0	14
Trypanothione reductase	0	1	0	1
Inositol hexakisphosphate kinase 1	14	0	0	14
cytochrome P450 2C9, partial	14	0	0	14
Chain A, Ferritin light chain	9	0	0	9
Caspase-2	0	0	1	1
PPM1D protein	8	0	0	8
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	1	0	1
Spike glycoprotein	0	1	2	3
Replicase polyprotein 1ab	0	1	2	3
glucose-6-phosphate 1-dehydrogenase isoform b	0	1	0	1
Transmembrane protease serine 2	0	1	2	3
Dihydrofolate reductase	0	2	0	2
DNA ligase	0	1	0	1
Riboflavin-binding protein	0	0	1	1
Major prion protein	0	0	1	1
Amyloid-beta precursor protein	0	6	0	6
Histidine-rich protein PFHRP-II	0	1	0	2
Procathepsin L	0	2	2	4
Muscarinic acetylcholine receptor M2	0	6	0	6
Muscarinic acetylcholine receptor M4	0	5	0	5
Muscarinic acetylcholine receptor M5	0	5	0	5
Alpha-2A adrenergic receptor	0	7	2	9
Replicase polyprotein 1a	0	1	2	3
Replicase polyprotein 1ab	0	1	2	3
Replicase polyprotein 1ab	0	2	2	4
Spike glycoprotein	0	1	0	1
Replicase polyprotein 1ab	0	3	2	5
Muscarinic acetylcholine receptor M1	0	5	0	5
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	1	0	1
Alpha-2C adrenergic receptor	0	4	1	5
DNA ligase 1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	4	1	5
Serine/threonine-protein kinase mTOR	0	1	0	1
Calcium-dependent protein kinase 1	0	0	1	1
MO15-related protein kinase Pfmrk	0	1	0	1
DNA ligase A	0	1	0	1
Sigma intracellular receptor 2	0	1	0	1
Phosphoethanolamine N-methyltransferase	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	12	0	12
Angiotensin-converting enzyme 2	0	1	2	3
Cysteine proteinase falcipain 2a	0	1	0	1
Cysteine proteinase falcipain 2a	0	1	0	1
EWS/FLI fusion protein	15	0	0	15
cytochrome P450 2C9 precursor	5	0	0	5
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	2
DNA gyrase subunit A	0	1	0	3
DNA gyrase subunit B	0	1	0	3
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	2
DNA topoisomerase 4 subunit A	0	1	0	2
DNA topoisomerase 2-alpha	0	1	0	4
DNA gyrase subunit A	0	1	0	2
Multidrug resistance protein MdtK	0	0	1	1
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	0	0	1
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	1
Integrase	0	1	0	1
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain H, Fab M82G2, Heavy chain	0	0	1	1
Chain L, Fab M82G2, Light chain	0	0	1	1
Chain H, Fab M82g2, Heavy Chain	0	0	1	1
Chain L, Fab M82g2, Light Chain	0	0	1	1
Gamma-aminobutyric acid receptor subunit pi	0	2	0	2
Gamma-aminobutyric acid receptor subunit delta	0	2	0	2
Fatty acid-binding protein, heart	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Muscarinic acetylcholine receptor M1	0	3	1	4
Tryptophan 5-hydroxylase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	3	1	4
Gamma-aminobutyric acid receptor subunit beta-1	0	2	1	3
Gamma-aminobutyric acid receptor subunit gamma-2	0	3	1	4
D	0	2	0	2
5-hydroxytryptamine receptor 1A	0	6	0	6
Alpha-2B adrenergic receptor	0	5	0	5
Alpha-2C adrenergic receptor	0	5	0	5
Alpha-2A adrenergic receptor	0	5	0	5
Liver carboxylesterase 1	0	1	0	2
Sodium-dependent noradrenaline transporter	0	12	3	15
Sodium-dependent dopamine transporter	0	5	0	5
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	4	0	4
Gamma-aminobutyric acid receptor subunit beta-3	0	3	1	4
5-hydroxytryptamine receptor 1B	0	3	0	3
5-hydroxytryptamine receptor 1D	0	1	0	1
5-hydroxytryptamine receptor 1F	0	1	0	1
5-hydroxytryptamine receptor 6	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	1	3
Sodium-dependent serotonin transporter	0	10	2	12
5-hydroxytryptamine receptor 7	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	1	3
5-hydroxytryptamine receptor 5A	0	1	0	1
5-hydroxytryptamine receptor 5B	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	5	2	9
5-hydroxytryptamine receptor 3A	0	1	0	1
Lysosomal Pro-X carboxypeptidase	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	1	3
Gamma-aminobutyric acid receptor subunit beta-2	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	1	3
Gamma-aminobutyric acid receptor subunit epsilon	0	2	0	2
Glutamate receptor ionotropic, NMDA 2A	0	5	2	9
Glutamate receptor ionotropic, NMDA 2C	0	5	2	10
Sodium-dependent dopamine transporter	0	10	1	11
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	4	0	4
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	4	0	4
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	1	3
Sodium-dependent dopamine transporter	0	2	0	2
Glutamate receptor ionotropic, NMDA 2D	0	5	2	9
5-hydroxytryptamine receptor 4	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	0	2
Glutamate receptor ionotropic, NMDA 3B	0	5	2	9
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	0	2
5-hydroxytryptamine receptor 3B	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	5	2	9
Gamma-aminobutyric acid receptor subunit theta	0	2	0	2
Transporter	0	4	0	4
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	13	0	0	13
Substance-P receptor	0	2	1	3
Neuromedin-K receptor	0	0	2	2
Substance-P receptor	0	7	2	9
Neuromedin-K receptor	0	2	1	3
Neuromedin-K receptor	0	1	0	1
Substance-P receptor	0	4	0	4
Substance-K receptor	0	2	0	2
serine/threonine-protein kinase mTOR isoform 1	6	0	0	6
Platelet-activating factor receptor	0	1	0	1
Alpha-synuclein	3	2	0	5
Phosphodiesterase	0	3	0	3
Multidrug resistance-associated protein 5	0	0	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	2	0	2
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	3	0	3
Glutathione S-transferase P	0	1	0	1
Alpha-tocopherol transfer protein	0	0	1	1
Lysine-specific demethylase 4A	0	1	0	1
Hypoxia-inducible factor 1-alpha	0	0	1	1
Methylcytosine dioxygenase TET2	0	1	0	1
Deoxyhypusine hydroxylase	0	1	0	1
Vascular endothelial growth factor receptor 2	0	2	0	2
Lactoylglutathione lyase	0	2	0	2
Histone acetyltransferase p300	0	1	0	1
CREB-binding protein	0	1	0	1
Cereblon isoform 4	0	2	0	2
Insulin-like growth factor-binding protein 5	0	0	1	1
Protein cereblon	0	2	0	2
Solute carrier family 22 member 2	0	1	0	3
Solute carrier family 22 member 1	0	2	0	4
Prostaglandin G/H synthase 2	0	3	0	4
Thromboxane A2 receptor	0	3	1	4
Prostaglandin E2 receptor EP1 subtype	0	3	2	5
Prostaglandin E2 receptor EP4 subtype	0	3	1	4
Prostaglandin F2-alpha receptor	0	2	0	2
Prostaglandin F2-alpha receptor	0	2	2	4
Prostaglandin E2 receptor EP3 subtype	0	3	2	5
Prostaglandin E2 receptor EP2 subtype	0	3	1	4
Prostaglandin F2-alpha receptor	0	0	1	1
Prostacyclin receptor	0	3	1	4
Prostaglandin D2 receptor	0	1	0	1
Solute carrier family 22 member 7	0	0	0	4
Solute carrier organic anion transporter family member 2A1	0	1	0	4
Solute carrier organic anion transporter family member 2A1	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	1	0	1
Solute carrier family 22 member 7	0	0	0	2
prostaglandin E2 receptor EP2 subtype	1	0	0	1
Solute carrier organic anion transporter family member 1A5	0	0	0	1
Prostaglandin E2 receptor EP3 subtype	0	2	0	2
Prostaglandin E2 receptor EP4 subtype	0	2	0	2
Prostaglandin E2 receptor EP1 subtype	0	2	0	2
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP2 subtype	0	2	0	2
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier family 22 member 20	0	3	0	3
Solute carrier family 22 member 6	0	3	0	3
Solute carrier family 22 member 7	0	0	0	1
Solute carrier organic anion transporter family member 1B2	0	0	0	1
mu-type opioid receptor isoform MOR-1	0	0	2	2
huntingtin isoform 2	3	0	0	3
5-hydroxytryptamine receptor 2A	0	0	2	2
Tyrosine-protein kinase Lck	0	2	0	2
Polyunsaturated fatty acid lipoxygenase ALOX15	0	3	0	3
POU domain, class 2, transcription factor 1	0	0	0	2
Alpha-1D adrenergic receptor	0	4	1	5
D(3) dopamine receptor	0	5	1	6
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
L-lactate dehydrogenase A chain	0	1	0	1
Fatty acid-binding protein, liver	0	1	0	1
Glutamate receptor 1	0	2	2	4
Glutamate receptor 3	0	2	2	4
Glutamate receptor 4	0	2	2	4
Glycine receptor subunit alpha-1	0	0	1	1
Cannabinoid receptor 1	0	1	0	1
Cannabinoid receptor 2	0	1	1	2
N-arachidonyl glycine receptor	0	0	1	1
Transient receptor potential cation channel subfamily A member 1	0	0	2	2
Lysophosphatidylserine lipase ABHD12	0	1	0	1
Monoglyceride lipase	0	1	0	1
Monoacylglycerol lipase ABHD6	0	1	0	1
Cannabinoid receptor 2	0	2	0	2
G-protein coupled receptor 55	0	1	1	2
lysosomal alpha-glucosidase preproprotein	2	0	0	2
histone-lysine N-methyltransferase 2A isoform 2 precursor	8	0	0	8
replicative DNA helicase	0	0	0	2
recombinase A	0	0	2	2
UDP-glucuronosyltransferase 1A9	0	0	0	4
UDP-glucuronosyltransferase 2B17	0	0	0	1
UDP-glucuronosyltransferase 2B7	0	1	0	4
UDP-glucuronosyltransferase 1-6	0	0	0	2
UDP-glucuronosyltransferase 1A1	0	0	0	1
UDP-glucuronosyltransferase 1A7	0	0	0	1
Eyes absent homolog 2	0	1	0	1
Metallo-beta-lactamase VIM-13	0	1	0	2
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase VIM-1	0	1	0	2
Endothelin-1 receptor	0	2	0	2
Cathepsin B	0	1	0	1
Proteasome subunit beta type-1	0	1	0	1
Cathepsin S	0	1	0	1
Proteasome subunit beta type-5	0	1	0	1
Proteasome subunit beta type-2	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	2	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	2	0	2
Thromboxane-A synthase	0	5	0	5
Cysteinyl leukotriene receptor 1	0	1	0	2
Cysteinyl leukotriene receptor 2	0	1	1	2
Cysteinyl leukotriene receptor 1	0	1	1	2
Membrane primary amine oxidase	0	1	0	1
Coagulation factor X	0	1	0	1
Plasminogen	0	2	0	2
Coagulation factor XII	0	1	0	1
Urokinase-type plasminogen activator	0	1	0	1
Tissue-type plasminogen activator	0	1	0	1
Serine protease hepsin	0	1	0	1
Multidrug and toxin extrusion protein 2	0	1	0	1
Multidrug and toxin extrusion protein 1	0	2	0	2
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
beta-2 adrenergic receptor	3	0	0	3
Metabotropic glutamate receptor 8	0	2	0	2
Metabotropic glutamate receptor 6	0	1	1	3
Glutamate receptor ionotropic, NMDA 2D	0	2	0	2
Excitatory amino acid transporter 4	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	2	0	2
Glutathione reductase, mitochondrial	0	3	0	4
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
ATP-citrate synthase	0	1	0	1
Glutamate receptor ionotropic, kainate 1	0	2	1	3
Metabotropic glutamate receptor 1	0	1	1	2
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 5	0	0	1	1
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Glutamate receptor ionotropic, kainate 1	0	1	1	2
Metabotropic glutamate receptor 5	0	1	1	3
Glutamate receptor ionotropic, kainate 2	0	2	1	3
Glutamate receptor 1	0	2	1	3
Glutamate receptor 2	0	2	1	3
Glutamate receptor 3	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	2	0	2
Excitatory amino acid transporter 1	0	2	0	3
Excitatory amino acid transporter 2	0	2	0	3
Excitatory amino acid transporter 3	0	2	0	3
Metabotropic glutamate receptor 8	0	0	1	1
Glutamate receptor 4	0	2	1	3
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Glutamate receptor ionotropic, kainate 4	0	2	0	2
Glutamate carboxypeptidase 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	3	0	3
Glutamate receptor ionotropic, NMDA 2A	0	3	0	3
Glutamate receptor ionotropic, kainate 2	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	3	0	3
Metabotropic glutamate receptor 1	0	1	1	3
Metabotropic glutamate receptor 2	0	1	1	3
Metabotropic glutamate receptor 7	0	1	1	3
Metabotropic glutamate receptor 3	0	1	1	3
Metabotropic glutamate receptor 4	0	1	1	3
Glutamate receptor ionotropic, NMDA 2C	0	2	0	2
Glutamate receptor ionotropic, kainate 5	0	1	0	1
Carbonic anhydrase-like protein, putative	0	0	0	4
Glutamate receptor ionotropic, kainate 5	0	2	0	2
Glutamate racemase	0	0	0	1
Prolyl 4-hydroxylase	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	2	0	2
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
Chain A, Glutamine Binding Protein	0	0	1	1
Neutral amino acid transporter A	0	2	0	2
Asc-type amino acid transporter 1	0	2	0	2
Neutral amino acid transporter B(0)	0	2	0	2
Amino acid transporter	0	2	0	2
Proton-coupled amino acid transporter 1	0	2	0	3
nonstructural protein 1	6	0	0	6
Acid-sensing ion channel 3	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	1	0	1
Bile salt export pump	0	4	0	4
Dihydrofolate reductase	0	1	0	1
Fatty acid-binding protein, liver	0	4	0	4
Albumin	0	4	3	7
Albumin	0	0	1	1
Cholinesterase	0	2	0	2
Prostaglandin G/H synthase 1	0	2	0	2
Caspase-1	0	2	0	3
UDP-glucuronosyltransferase 1A3	0	0	0	2
Aldo-keto reductase family 1 member C3	0	3	0	3
Caspase-3	0	2	0	2
Solute carrier organic anion transporter family member 1A1	0	1	0	1
Caspase-4	0	2	0	2
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Cytochrome P450 2J2	0	4	0	4
Caspase-5	0	2	0	2
Caspase-9	0	2	0	2
Acid-sensing ion channel 1	0	1	0	1
Prostaglandin G/H synthase 2	0	2	0	3
Dehydrogenase/reductase SDR family member 9	0	1	0	1
Chain A, Cell Division Protein Kinase 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, Cell Division Protein Kinase 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, Cell Division Protein Kinase 2	0	1	0	1
Cyclin-dependent kinase 1	0	1	0	1
G2/mitotic-specific cyclin-B1	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	0	1	1
RAC-alpha serine/threonine-protein kinase	0	1	0	1
Cyclin-A1	0	1	0	1
Chain A, membrane-associated prostaglandin E synthase-2	0	1	0	1
Parkin	5	0	0	5
M-phase phosphoprotein 8	5	0	0	5
Prostaglandin-H2 D-isomerase	0	1	0	1
Prostaglandin E synthase	0	1	0	1
3',5'-cyclic-AMP phosphodiesterase	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	2	0	2
Cytochrome c oxidase subunit 2	0	1	0	1
Phospholipase A2, major isoenzyme	0	1	0	1
ATP-dependent translocase ABCB1	0	6	1	7
Neuronal acetylcholine receptor subunit alpha-4	1	1	0	2
Interleukin-8	0	1	0	1
Androgen receptor	0	2	1	3
Neuronal acetylcholine receptor subunit beta-2	1	1	0	2
Aldo-keto reductase family 1 member B1	0	2	0	2
Aldo-keto reductase family 1 member B1	0	2	0	2
Aldo-keto reductase family 1 member C4	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	2	0	2
Multidrug resistance-associated protein 1	0	1	0	1
Bifunctional epoxide hydrolase 2	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	0	1	1
C-X-C chemokine receptor type 3	0	1	0	1
Aldo-keto reductase family 1 member C2	0	1	0	1
Prostaglandin D2 receptor	0	2	0	2
Solute carrier organic anion transporter family member 1A3	0	1	0	1
Aldo-keto reductase family 1 member C1	0	1	0	1
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Rho-associated protein kinase 2	0	1	0	1
Nicotinate phosphoribosyltransferase	0	2	0	2
Dehydrogenase/reductase SDR family member 9	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Prostaglandin D2 receptor 2	0	1	1	2
Beta-1 adrenergic receptor	0	0	1	2
hexokinase-4 isoform 1	1	0	0	1
glucokinase regulatory protein	1	0	0	1
Beta-2 adrenergic receptor	0	2	1	3
D(2) dopamine receptor	0	3	0	3
Alpha-1B adrenergic receptor	0	9	0	9
Beta-1 adrenergic receptor	0	3	1	5
Beta-2 adrenergic receptor	0	0	1	1
D(1A) dopamine receptor	0	3	0	3
D(4) dopamine receptor	0	3	0	3
Alpha-1D adrenergic receptor	0	6	0	6
Beta-adrenergic receptor kinase 1	0	0	1	1
Beta-3 adrenergic receptor	0	0	1	1
Beta-3 adrenergic receptor	0	1	1	2
Beta-1 adrenergic receptor	0	1	1	2
Alpha-1A adrenergic receptor	0	1	2	3
Alpha-1B adrenergic receptor	0	1	2	3
Alpha-1A adrenergic receptor	0	9	0	9
Beta-2 adrenergic receptor	0	1	0	1
Taste receptor type 2 member 38	0	0	1	1
Taste receptor type 2 member 39	0	0	1	1
Taste receptor type 2 member 40	0	0	1	1
Taste receptor type 2 member 41	0	0	1	1
Taste receptor type 2 member 43	0	0	1	1
Taste receptor type 2 member 31	0	0	1	1
Taste receptor type 2 member 45	0	0	1	1
Taste receptor type 2 member 46	0	0	1	1
Taste receptor type 2 member 30	0	0	1	1
Taste receptor type 2 member 19	0	0	1	1
Taste receptor type 2 member 20	0	0	1	1
Taste receptor type 2 member 50	0	0	1	1
Taste receptor type 2 member 60	0	0	1	1
Taste receptor type 2 member 42	0	0	1	1
Taste receptor type 2 member 16	0	0	1	1
Taste receptor type 2 member 14	0	0	1	2
Taste receptor type 2 member 13	0	0	1	1
Taste receptor type 2 member 10	0	0	1	1
Taste receptor type 2 member 9	0	0	1	1
Taste receptor type 2 member 8	0	0	1	1
Taste receptor type 2 member 7	0	0	1	1
Taste receptor type 2 member 5	0	0	1	1
Taste receptor type 2 member 4	0	0	1	1
Taste receptor type 2 member 3	0	0	1	1
Taste receptor type 2 member 1	0	0	1	1
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	2	0	0	2
Cell division control protein 42 homolog	0	1	0	1
Ras-related C3 botulinum toxin substrate 1	0	1	0	1
Serine/threonine-protein kinase PAK 1	0	1	0	1
Chain A, AMINOPEPTIDASE	0	2	0	2
Chain A, AMINOPEPTIDASE	0	2	0	2
Chain A, Leucine Aminopeptidase	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	4	0	4
Intestinal-type alkaline phosphatase	0	3	0	3
Large neutral amino acids transporter small subunit 1	0	3	0	4
Phospholipase A-2-activating protein	0	3	0	3
Canalicular multispecific organic anion transporter 1	0	1	0	1
P2Y purinoceptor 12	0	0	1	1
Tyrosine-protein kinase ABL1	0	2	0	2
Methionine aminopeptidase	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	2	0	2
Calmodulin-domain protein kinase 1	0	1	0	1
Solute carrier family 22 member 3	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Synaptic vesicular amine transporter	0	1	0	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Solute carrier family 22 member 8	0	1	0	1
Chain E, Fibrin beta chain	0	1	0	1
T cell receptor, partial	1	0	0	1
luteinizing hormone receptor	1	0	0	1
integrase, partial	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	2	0	0	2
lens epithelium-derived growth factor p75	0	1	0	1
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	1
ATAD5 protein, partial	6	0	0	6
TSHR protein	1	0	0	1
Apoptotic peptidase activating factor 1	0	1	0	1
hypothetical protein, conserved	1	0	0	1
isocitrate dehydrogenase 1, partial	2	0	0	2
luciferase	1	0	0	1
serine-protein kinase ATM isoform a	3	0	0	3
neutrophil cytosol factor 1	0	1	0	1
caspase-9 isoform alpha precursor	0	1	0	1
caspase-3 isoform a preproprotein	0	1	0	1
protein AF-9 isoform a	0	0	0	1
Vpr	2	0	0	2
POsterior Segregation	0	0	1	1
DNA repair protein RAD52 homolog isoform a	0	0	0	1
Glutathione reductase	0	1	0	1
Dihydrolipoyl dehydrogenase, mitochondrial	0	1	0	2
Microtubule-associated protein tau	0	1	1	2
Cruzipain	0	1	0	1
Thioredoxin reductase 1, cytoplasmic	0	1	0	2
Dihydrolipoyl dehydrogenase	0	1	0	2
Zinc finger protein mex-5	0	0	1	1
phosphoglycerate kinase	1	0	0	1
Glucocorticoid receptor	0	8	3	16
Glycine receptor subunit alpha-1	0	8	0	8
Glycine receptor subunit beta	0	8	0	8
Glycine receptor subunit alpha-2	0	8	0	8
Glycine receptor subunit alpha-3	0	8	0	8
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Nuclear receptor corepressor 1	0	1	0	1
Integrin beta-1	0	1	0	1
Leukotriene A-4 hydrolase	0	1	0	1
Integrin alpha-4	0	1	0	1
Nuclear receptor corepressor 2	0	1	0	1
Opioid receptor, delta 1b	0	1	0	1
Opioid receptor homologue	0	1	0	1
ATP-dependent translocase ABCB1	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	2	1	3
Muscarinic acetylcholine receptor M4	0	2	1	3
Muscarinic acetylcholine receptor M5	0	2	1	3
Muscarinic acetylcholine receptor M2	0	2	1	3
Histidine decarboxylase	0	0	1	1
ATP-dependent translocase ABCB1	0	1	0	1
Proteinase-activated receptor 1	0	1	1	2
Kappa-type opioid receptor	0	2	1	5
Kappa-type opioid receptor	0	2	1	4
Mu-type opioid receptor	0	2	1	6
Nociceptin receptor	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Mas-related G-protein coupled receptor member X2	0	0	2	2
Mu-type opioid receptor	0	1	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	3	0	0	3
Neutrophil elastase	0	2	0	2
Collagenase 3	0	2	0	2
Sodium/iodide cotransporter	0	1	0	1
Chain A, Adipocyte Lipid-binding Protein	0	0	1	1
Chain A, MUSCLE FATTY ACID BINDING PROTEIN	0	0	1	1
Chain A, MUSCLE FATTY ACID BINDING PROTEIN	0	0	1	1
Chain A, MUSCLE FATTY ACID BINDING PROTEIN	0	0	1	1
Chain A, BCL-2-RELATED PROTEIN A1	0	0	1	1
putative potassium channel subunit	0	0	1	1
bcl-2-like protein 11 isoform 1	0	0	1	1
Sterol O-acyltransferase 1	0	1	0	1
Fatty acid-binding protein, liver	0	0	1	1
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
DNA topoisomerase 1	0	1	0	1
Protein kinase C alpha type	0	1	0	2
Tyrosine-protein phosphatase non-receptor type 1	0	2	0	4
Sterol O-acyltransferase 1	0	1	0	1
Peroxisome proliferator-activated receptor delta	0	0	0	1
Peroxisome proliferator-activated receptor alpha	1	0	1	2
Rap guanine nucleotide exchange factor 4	1	0	0	1
cystic fibrosis transmembrane conductance regulator	0	1	0	1
Thromboxane-A synthase	0	2	0	2
Photosystem I iron-sulfur center	0	0	0	1
vasopressin V1b receptor	1	0	0	1
relaxin receptor 1 isoform 1	1	0	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	2	0	2
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	1	0	1
Tumor necrosis factor	0	1	0	1
Chitotriosidase-1	0	3	1	4
Endochitinase B1	0	3	1	4
Chain A, Immunoglobulin	0	0	1	1
Chain B, Immunoglobulin	0	0	1	1
Muscarinic acetylcholine receptor M1	0	0	1	2
Muscarinic acetylcholine receptor M4	0	0	1	2
Cholinesterase	0	1	0	1
Muscarinic acetylcholine receptor M5	0	0	1	2
Muscarinic acetylcholine receptor M3	0	0	1	2
Muscarinic acetylcholine receptor M2	0	0	1	2
Sigma non-opioid intracellular receptor 1	0	3	0	3
Retinoid isomerohydrolase	0	1	0	1
Retinoid isomerohydrolase	0	1	0	1
Retinoid isomerohydrolase	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Plasma kallikrein	0	0	0	2
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
5'-nucleotidase	0	1	0	1
E3 ubiquitin-protein ligase XIAP	0	1	0	1
SLC16A10 protein	0	0	0	2
Large neutral amino acids transporter small subunit 1	0	1	0	1
Monocarboxylate transporter 10	0	0	0	2
Alpha-1B adrenergic receptor	0	0	1	1
Alpha-1A adrenergic receptor	0	2	1	3
Alpha-1B adrenergic receptor	0	1	0	1
Alpha-2B adrenergic receptor	0	0	0	1
Alpha-2C adrenergic receptor	0	0	0	1
Alpha-2A adrenergic receptor	0	0	0	1
Gamma-aminobutyric acid	0	1	0	1
atrial natriuretic peptide receptor 1 precursor	3	0	0	3
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	2	0	2
Sodium channel protein type 2 subunit alpha	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	1	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1S	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Sodium channel protein type 5 subunit alpha	0	1	0	1
Sodium channel protein type 9 subunit alpha	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Complement C1s subcomponent	0	1	0	1
Nitric oxide synthase, inducible	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase type 2	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-19	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase OXA-7	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Class D beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-b-lactamase	0	0	0	1
BlaVIM-1	0	0	0	1
Beta-lactamase	0	0	0	1
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	1
Beta-lactamase class B VIM-2	0	0	0	1
luciferase	0	0	0	1
Estrogen receptor	0	5	1	7
Progesterone receptor	0	4	0	5
Glucocorticoid receptor	0	2	1	3
Glucocorticoid receptor	0	0	1	1
Corticosteroid-binding globulin	0	1	0	1
Mineralocorticoid receptor	0	3	2	5
Glutamine synthetase	0	0	1	1
Histamine H1 receptor	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	5	1	6
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Vascular cell adhesion protein 1	0	1	0	1
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	2	0	2
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
5-hydroxytryptamine receptor 4	0	6	0	6
Gamma-aminobutyric acid receptor subunit alpha-1	0	0	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	0	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	0	0	1
5-hydroxytryptamine receptor 2C	0	6	0	6
5-hydroxytryptamine receptor 2B	0	8	0	8
UDP-glucuronosyltransferase 1A8	0	0	0	1
Interleukin-5	0	1	0	1
Interleukin-5	0	1	0	1
Matrix metalloproteinase-9	0	1	0	1
Interleukin-5 receptor subunit alpha	0	1	0	1
Chain A, Mitogen-activated protein kinase 10	0	1	0	1
Chain A, Mitogen-activated protein kinase 10	0	1	0	1
Chain A, Mitogen-activated protein kinase 10	0	1	0	1
RGS12	1	0	0	1
TPA: protein transporter TIM10	0	1	0	1
TPA: protein transporter TIM23	0	1	0	1
guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1	1	0	0	1
polyadenylate-binding protein 1	0	1	0	1
Serine/threonine-protein kinase PLK4	0	0	1	1
Aurora kinase A	0	0	1	1
Cyclin-G-associated kinase	0	0	1	1
3-phosphoinositide-dependent protein kinase 1	0	0	1	1
Death-associated protein kinase 3	0	0	1	1
Serine/threonine-protein kinase/endoribonuclease IRE1	0	1	0	1
Ribosomal protein S6 kinase alpha-5	0	0	1	1
Serine/threonine-protein kinase 16	0	0	1	1
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	1	1
Interferon-induced, double-stranded RNA-activated protein kinase	0	1	0	1
Ephrin type-A receptor 3	0	0	1	1
Dual specificity protein kinase TTK	0	1	1	2
Mitogen-activated protein kinase 8	0	1	1	2
Mitogen-activated protein kinase 9	0	1	1	2
Casein kinase I isoform epsilon	0	0	1	1
Dual specificity protein kinase CLK2	0	0	1	1
Tyrosine-protein kinase JAK3	0	1	0	1
Mitogen-activated protein kinase 10	0	1	1	2
Cyclin-dependent kinase 16	0	0	1	1
Serine/threonine-protein kinase 4	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1	0	0	1	1
Ribosomal protein S6 kinase alpha-2	0	0	1	1
AP2-associated protein kinase 1	0	0	1	1
Serine/threonine-protein kinase ULK3	0	0	1	1
Serine/threonine-protein kinase MARK2	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1D	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1G	0	0	1	1
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	1	1
Single-stranded DNA cytosine deaminase	1	0	0	1
STE20-like serine/threonine-protein kinase	0	0	1	1
Dual specificity protein kinase CLK4	0	0	1	1
MAP kinase-interacting serine/threonine-protein kinase 2	0	0	1	1
Casein kinase I isoform gamma-1	0	0	1	1
Serine/threonine-protein kinase 3	0	0	1	1
BMP-2-inducible protein kinase	0	0	1	1
Serine/threonine-protein kinase pim-2	0	0	1	1
Serine/threonine-protein kinase 17A	0	0	1	1
Death-associated protein kinase 2	0	0	1	1
TRAF2 and NCK-interacting protein kinase	0	0	1	1
Aurora kinase C	0	0	1	1
Serine/threonine-protein kinase 38-like	0	0	1	1
Estrogen receptor beta	0	0	0	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Polymerase acidic protein	0	0	1	1
Stromelysin-1	0	0	1	1
Tyrosine-protein phosphatase YopH	0	1	0	1
High mobility group protein B1	0	0	1	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Estrogen receptor	0	0	0	1
Cystathionine gamma-lyase	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
atrial natriuretic peptide receptor 2 precursor	2	0	0	2
Transcriptional activator protein LuxR	0	2	0	2
Angiotensin-converting enzyme	0	4	0	4
D(3) dopamine receptor	0	3	0	3
D(1B) dopamine receptor	0	1	0	1
5-hydroxytryptamine receptor 2A	0	4	0	4
D(4) dopamine receptor	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	1	0	1
Melanocortin receptor 5	0	4	0	4
Envelope glycoprotein	0	0	1	1
Nuclear receptor subfamily 3 group C member 3	0	4	0	4
PINK1	1	0	0	1
photoreceptor-specific nuclear receptor	0	1	0	1
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	2	0	2
Insulin receptor	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Substance-K receptor	0	1	0	1
Substance-K receptor	0	6	0	6
Substance-K receptor	0	1	1	2
Substance-K receptor	0	1	0	1
Growth hormone secretagogue receptor type 1	0	0	1	1
Thromboxane A2 receptor	0	1	0	1
Chain A, CES1 protein	0	1	0	1
DNA polymerase III, partial	1	0	0	1
interferon gamma precursor	0	0	0	1
ubiquitin-conjugating enzyme E2 N	0	1	0	1
streptokinase A precursor	0	0	1	1
Serine/threonine-protein kinase D3	0	1	0	1
Lysosomal acid glucosylceramidase	0	0	1	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C alpha type	0	1	0	1
Protein kinase C beta type	0	1	0	1
Estrogen receptor	0	0	1	2
Protein kinase C delta type	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
Steroid hormone receptor ERR1	0	1	0	1
Protein kinase C eta type	0	1	0	1
Histamine H2 receptor	0	2	0	2
Melanocortin receptor 4	0	2	0	2
C-8 sterol isomerase	0	1	0	1
Protein kinase C iota type	0	1	0	1
Melanocortin receptor 3	0	2	0	2
5-hydroxytryptamine receptor 6	0	2	0	2
Estrogen-related receptor gamma	0	1	0	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C beta type	0	1	0	1
Phospholipase D1	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C theta type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
Protein kinase C delta type	0	1	0	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Platelet-activating factor acetylhydrolase	0	1	0	1
Phospholipase D1	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	2	1	3
Serine/threonine-protein kinase D1	0	1	0	1
Estrogen receptor beta	0	0	1	2
Protein kinase C eta type	0	1	0	1
Emopamil-binding protein-like	0	1	0	1
7-dehydrocholesterol reductase	0	1	1	2
Protein kinase C theta type	0	1	0	1
Endothelin receptor type B	0	1	0	1
Chain A, Pyridoxal kinase	0	1	0	1
Chain A, Pyridoxal Kinase	0	1	0	1
5-hydroxytryptamine receptor 1A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Thyroid hormone receptor beta	0	1	0	1
Adenosine receptor A1	0	2	0	2
Vasopressin V2 receptor	0	0	0	1
Adenosine receptor A2a	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	1	0	1
Adenosine receptor A1	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	2	0	2
Adenylate cyclase type 1	0	0	0	1
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Adenosine receptor A2b	0	0	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	0	1	1
Alcohol dehydrogenase E chain	0	1	0	1
Alcohol dehydrogenase S chain	0	1	0	1
Urease subunit alpha	0	1	0	1
Urease subunit alpha	0	1	0	1
Urease subunit beta	0	1	0	1
Urease subunit beta	0	1	0	1
Serine-protein kinase ATM	0	1	0	1
Serine/threonine-protein kinase ATR	0	1	0	1
Chain A, Carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
MSH	0	0	0	1
pyruvate kinase	1	0	0	1
pyruvate kinase PKM isoform b	1	0	0	1
Hematopoietic prostaglandin D synthase	0	1	0	1
Ornithine decarboxylase	1	0	0	2
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
Transient receptor potential cation channel subfamily V member 2	0	1	0	1
Chain A, Nuclear Receptor ROR-beta	0	1	0	1
Ornithine decarboxylase	0	0	0	1
Retinoic acid receptor alpha	0	2	2	7
Retinoic acid receptor beta	0	2	2	7
Retinoic acid receptor alpha	0	1	2	3
Retinoic acid receptor gamma	0	2	2	7
Retinoic acid receptor gamma	0	1	2	3
Retinoic acid receptor RXR-alpha	0	2	2	4
Retinoic acid receptor beta	0	1	2	3
Cellular retinoic acid-binding protein 2	0	0	1	1
Mitogen-activated protein kinase 1	0	1	0	1
Retinoic acid receptor RXR-alpha	0	1	2	3
Retinoic acid receptor RXR-beta	0	2	2	4
Retinoic acid receptor RXR-beta	0	1	2	3
Retinoic acid receptor RXR-gamma	0	1	2	3
Nuclear receptor ROR-alpha	0	1	0	1
Cellular retinoic acid-binding protein 1	0	1	0	2
Retinoic acid receptor RXR-gamma	0	2	2	4
Cellular retinoic acid-binding protein 1	0	0	1	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	2	1	3
Indoleamine 2,3-dioxygenase 2	0	1	0	1
Nuclear receptor ROR-beta	0	1	0	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Cocaine esterase	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member B7	0	1	0	1
D-alanyl-D-alanine dipeptidase	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(3)

Research Excerpts

Overview

Context

Actions

Treatment

Research

Studies (480)

Protein Targets (1,401)

Inhalation Injury, Smoke

Synonyms(3)

Research Excerpts

Overview

Context

Actions

Treatment

Research

Studies (480)

Drugs Studied (264)

Protein Targets (1,401)