Page last updated: 2024-09-27

Infusion Site Adverse Event

Adverse reactions that occur initially at the site of injection or infusion. Milder type is confined to a local allergic flare reaction. A more severe reaction is caused by extravasation of VESICANTS from the blood vessel at the site of injection and can cause damage to the surrounding tissue. In tumor flare reaction symptoms involve well beyond the injection site such as an increase in the tumor size and tumor markers levels, bone pain, and HYPERCALCEMIA.

Synonyms(6)

Synonym
Infusion Site Reaction
Injection Site Event
Injection Site Reaction
Infusion Site Adverse Event
Infusion Site Adverse Reaction
Injection Site Adverse Event

Research Excerpts

Overview

ExcerptReference
"Infusion site reactions are common following subcutaneous infusion of drugs."( Nemas, M; Nyska, A; Ramot, Y; Rubinski, A; Schiffenbauer, YS; Shaltiel-Karyo, R; Tsarfati, Y; Weinstock, I; Yacoby-Zeevi, O; Zawoznik, E, 2017)

Treatment

ExcerptReference
"To evaluate injection site reactions and pain following paliperidone palmitate 1-month (PP1M) and 3-month (PP3M) administration using safety data of double-blind (DB), noninferiority study."( Alphs, L; Elefant, E; Gopal, S; Kern Sliwa, J; Mathews, M; Najarian, D; Nuamah, I; Savitz, A, 2018)

Research

Studies (92)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's0 (0.00)12.5806
2000's0 (0.00)18.1394
2010's50 (54.35)28.8240
2020's42 (45.65)9.53
DrugIndicatedRelationship StrengthStudiesTrials
adenine0medium11
citric acid, anhydrous0medium21
3-cresol0low10
thiosulfates0low10
acetaminophen0medium31
amiodarone0low10
chlorambucil0low10
diphenhydramine0low10
fenofibrate0medium11
fluorouracil0medium21
hydroxychloroquine0low10
lidocaine0medium21
khellin0medium11
potassium chloride0medium11
propofol0medium41
risperidone0medium11
prednisolone0low10
prednisone0low10
apomorphine0low30
levodopa0low20
colchicine0low10
medroxyprogesterone acetate0low10
triamcinolone acetonide0low10
methylprednisolone0medium11
4-butyrolactone0medium11
azacitidine0low10
methamphetamine0low20
congo red0low10
deoxycytidine0low10
durapatite0low40
vancomycin0low10
d-alpha tocopherol0low10
thioflavin t0low10
sodium thiosulfate0low10
calcium sulfate0low10
trolamine salicylate0medium11
tiletamine hydrochloride0low10
phenyl acetate0medium11
epirubicin0low10
gemcitabine0low10
emtricitabine0medium11
triazoles0low10
bendamustine hydrochloride0medium11
carbidopa, levodopa drug combination0low10
methotrexate0medium51
docetaxel anhydrous0low10
ezetimibe0medium21
deoxycholic acid0low10
carboplatin0low10
inositol 3-phosphate0low30
tacrolimus0low10
cocaine0low10
dactinomycin0medium11
tenofovir0medium11
buprenorphine0low10
leuprolide0low10
etomidate0low20
bilirubin0low10
cholecalciferol0low10
montelukast0medium11
phenylephrine hydrochloride0low10
levetiracetam0low10
oxycodone0low10
vitamin k 10low10
clobetasol0low10
aluminum0low20
heroin0low10
rilpivirine0medium11
isavuconazole0low10
paliperidone palmitate0medium11
dehydroxymethylepoxyquinomicin0low10
g(m2) ganglioside0medium11
monomethyl auristatin e0medium11
jaw0medium21
enfuvirtide0low10
oligonucleotides0medium31
glucagon-like peptide 10low10
acetyl-2-naphthylalanyl-3-chlorophenylalanyl-1-oxohexadecyl-seryl-4-aminophenylalanyl(hydroorotyl)-4-aminophenylalanyl(carbamoyl)-leucyl-ilys-prolyl-alaninamide0medium11
natriuretic peptide, c-type0medium11
quetiapine fumarate0low10
exenatide0low10
gsk12657440medium11
pf 35126760low10
bictegravir0medium11
glucagon-like peptide 20medium11
hyaluronoglucosaminidase0low20
humulin s0low10
bmn 1110medium11
aprepitant0low10
fosaprepitant0low10
eye0medium11
carbidopa0low10
metallothionein0low10

Protein Targets (827)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
GLI family zinc finger 3210021
retinoid X nuclear receptor alpha170017
pregnane X nuclear receptor210021
peroxisome proliferator-activated receptor delta160016
vitamin D (1,25- dihydroxyvitamin D3) receptor180018
thyroid hormone receptor beta isoform a6006
nuclear factor erythroid 2-related factor 2 isoform 1200020
DNA polymerase kappa isoform 17007
histone acetyltransferase KAT2A isoform 16006
Acetylcholinesterase0202
RAR-related orphan receptor gamma220022
nuclear receptor subfamily 1, group I, member 3190019
estrogen-related nuclear receptor alpha270027
ATAD5 protein, partial100010
GLS protein7007
Microtubule-associated protein tau110011
Smad34004
aldehyde dehydrogenase 1 family, member A1150015
thyroid stimulating hormone receptor9009
progesterone receptor160016
EWS/FLI fusion protein140014
retinoic acid nuclear receptor alpha variant 1200020
estrogen nuclear receptor alpha320032
peroxisome proliferator activated receptor gamma190019
aryl hydrocarbon receptor130013
chromobox protein homolog 1120012
thyroid hormone receptor beta isoform 2210021
peripheral myelin protein 22150015
cytochrome P450 3A4 isoform 1120012
Gamma-aminobutyric acid receptor subunit pi121114
ATP-binding cassette sub-family C member 3022022
Multidrug resistance-associated protein 4022023
Solute carrier family 22 member 60101
Carbonic anhydrase 120203
UDP-glucuronosyltransferase 1A90002
Bile salt export pump0202
Voltage-dependent calcium channel gamma-2 subunit140014
Bile salt export pump026026
Cytochrome P450 2B10001
Cytochrome P450 1A10001
Carbonic anhydrase 10506
Carbonic anhydrase 20517
Myoglobin0101
Cytochrome P450 1A10214
Cytochrome P450 1A20304
Prostaglandin G/H synthase 10101
Carbonic anhydrase 30102
Cytochrome P450 3A40808
Cytochrome P450 2D60708
Cytochrome P450 2C9 0505
Polyunsaturated fatty acid lipoxygenase ALOX150303
Gamma-aminobutyric acid receptor subunit beta-1121114
Sulfotransferase 1A1 0001
Gamma-aminobutyric acid receptor subunit delta121114
Gamma-aminobutyric acid receptor subunit gamma-2121114
UDP-glucuronosyltransferase 1-60102
Glutamate receptor 2140014
Gamma-aminobutyric acid receptor subunit alpha-5121114
Gamma-aminobutyric acid receptor subunit alpha-3121114
Arachidonate 5-lipoxygenase-activating protein0101
UDP-glucuronosyltransferase 1A1 0104
Carbonic anhydrase 40203
Prostaglandin G/H synthase 10202
Carbonic anhydrase 60203
Gamma-aminobutyric acid receptor subunit gamma-1121114
Gamma-aminobutyric acid receptor subunit alpha-2121114
Gamma-aminobutyric acid receptor subunit alpha-4121114
Gamma-aminobutyric acid receptor subunit gamma-3121114
Gamma-aminobutyric acid receptor subunit alpha-6121114
Carbonic anhydrase 5A, mitochondrial0203
Prostaglandin G/H synthase 20102
Carbonic anhydrase 70102
Nuclear receptor ROR-gamma8008
Cytochrome P450 2J20303
Gamma-aminobutyric acid receptor subunit alpha-1121114
Gamma-aminobutyric acid receptor subunit beta-3121114
Gamma-aminobutyric acid receptor subunit beta-2121114
Carbonic anhydrase 90304
GABA theta subunit121114
Canalicular multispecific organic anion transporter 1022022
Carbonic anhydrase 150102
Carbonic anhydrase 130102
Gamma-aminobutyric acid receptor subunit epsilon121114
Carbonic anhydrase 140102
Carbonic anhydrase 5B, mitochondrial0102
toxin B0001
Gonadotropin-releasing hormone receptor0213
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE110011
Chain A, MTA/SAH nucleosidase0101
Chain A, Ribosome-inactivating protein alpha-trichosanthin0011
Chain A, Ricin A chain0011
Chain A, Ribosome-inactivating protein 30011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
TDP1 protein270027
AR protein290029
cytochrome P450 family 3 subfamily A polypeptide 4200020
glucocorticoid receptor [Homo sapiens]240024
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a180018
nuclear factor erythroid 2-related factor 2 isoform 2100010
heat shock protein beta-17007
importin subunit beta-1 isoform 15005
snurportin-15005
tumor susceptibility gene 101 protein1001
GTP-binding nuclear protein Ran isoform 13003
lamin isoform A-delta10190019
Cyclin-dependent kinase 10101
Heat shock protein HSP 90-beta0101
Xanthine dehydrogenase/oxidase0101
TAR DNA-binding protein 434004
Protein mono-ADP-ribosyltransferase PARP150101
Leucine-rich repeat serine/threonine-protein kinase 20202
ATPase family AAA domain-containing protein 5130013
Ataxin-2150015
Chain A, TYROSYL-DNA PHOSPHODIESTERASE8008
acetylcholinesterase7007
phosphopantetheinyl transferase9009
hypoxia-inducible factor 1 alpha subunit100010
SMAD family member 23003
Fumarate hydratase4004
USP1 protein, partial120012
NFKB1 protein, partial3003
PPM1D protein6006
SMAD family member 33003
Thrombopoietin6006
caspase 7, apoptosis-related cysteine protease6006
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)9009
estrogen receptor 2 (ER beta)120012
farnesoid X nuclear receptor140014
G120012
cytochrome P450 2D6120012
polyprotein4004
caspase-36006
euchromatic histone-lysine N-methyltransferase 2190019
thyroid stimulating hormone receptor100010
v-jun sarcoma virus 17 oncogene homolog (avian)130013
Histone H2A.x9009
cytochrome P450 2D6 isoform 16006
cellular tumor antigen p53 isoform a5005
cytochrome P450 2C9 precursor4004
D(1A) dopamine receptor2002
potassium voltage-gated channel subfamily H member 2 isoform d7007
huntingtin isoform 25005
mitogen-activated protein kinase 15005
flap endonuclease 17007
serine/threonine-protein kinase mTOR isoform 14004
peptidyl-prolyl cis-trans isomerase NIMA-interacting 14004
urokinase-type plasminogen activator precursor4004
plasminogen precursor4004
urokinase plasminogen activator surface receptor precursor4004
nuclear receptor ROR-gamma isoform 19009
geminin190019
survival motor neuron protein isoform d9009
muscarinic acetylcholine receptor M1100010
lethal factor (plasmid)4004
Polyunsaturated fatty acid lipoxygenase ALOX15B2002
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Solute carrier organic anion transporter family member 1A40101
Voltage-dependent L-type calcium channel subunit alpha-1F0202
5-hydroxytryptamine receptor 4010111
Lysine-specific demethylase PHF20101
Interferon beta180018
HLA class I histocompatibility antigen, B alpha chain 120012
Thyroid hormone receptor alpha0101
Receptor tyrosine-protein kinase erbB-20202
Cellular tumor antigen p53250025
Integrin beta-34105
Tyrosine-protein kinase Fyn0505
ATP-dependent translocase ABCB10202
Aldo-keto reductase family 1 member B1010010
Muscarinic acetylcholine receptor M20707
Muscarinic acetylcholine receptor M40606
ATP-dependent translocase ABCB104110
Integrin alpha-IIb4004
Beta-1 adrenergic receptor0202
Muscarinic acetylcholine receptor M50606
Alpha-2A adrenergic receptor0808
Adenosine receptor A30707
Cytochrome P450 2C80202
Thyroid hormone receptor alpha0101
Thyroid hormone receptor beta0101
Muscarinic acetylcholine receptor M10808
Beta-3 adrenergic receptor0606
D(2) dopamine receptor06210
Androgen receptor0707
Alpha-1B adrenergic receptor0909
Lethal factor0101
Alpha-2B adrenergic receptor0505
Thyroid hormone receptor beta0101
Muscarinic acetylcholine receptor M30909
ATP-dependent translocase ABCB10303
Substance-K receptor0606
D(1A) dopamine receptor06210
D(4) dopamine receptor0517
Carnitine O-palmitoyltransferase 2, mitochondrial0101
Sodium-dependent noradrenaline transporter 012113
Histamine H2 receptor0606
Endothelin-1 receptor0202
5-hydroxytryptamine receptor 2A0909
5-hydroxytryptamine receptor 2C010010
Lysine-specific demethylase 5A0101
B2 bradykinin receptor0202
Sodium-dependent serotonin transporter0516
Melanocortin receptor 40202
C-8 sterol isomerase0101
Melanocortin receptor 50404
Mu-type opioid receptor05310
D(3) dopamine receptor010112
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 4 subunit alpha0202
Squalene synthase0101
Delta-type opioid receptor08313
Kappa-type opioid receptor05210
5-hydroxytryptamine receptor 2B010010
C-C chemokine receptor type 20202
Melanocortin receptor 30202
Alpha-1A adrenergic receptor0909
Histamine H2 receptor4005
D(1A) dopamine receptor2002
5-hydroxytryptamine receptor 60303
Carnitine O-palmitoyltransferase 1, liver isoform0101
C-C chemokine receptor type 40202
Spike glycoprotein160218
Sodium channel protein type 7 subunit alpha0101
Voltage-dependent L-type calcium channel subunit alpha-1D 0202
Sodium-dependent dopamine transporter 0808
Potassium voltage-gated channel subfamily H member 2010010
Voltage-dependent L-type calcium channel subunit alpha-1S0202
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Sodium channel protein type 5 subunit alpha0404
Squalene monooxygenase0101
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0101
Sodium channel protein type 9 subunit alpha0202
Lysine-specific demethylase 7A0101
Carnitine O-palmitoyltransferase 1, muscle isoform0101
Inositol hexakisphosphate kinase 1120012
Sodium channel protein type 2 subunit alpha0101
Sigma non-opioid intracellular receptor 10808
NAD-dependent protein deacetylase sirtuin-3, mitochondrial0011
Sodium channel protein type 3 subunit alpha0202
Sodium channel protein type 11 subunit alpha0101
Histone lysine demethylase PHF80101
Sodium channel protein type 8 subunit alpha0101
Sodium channel protein type 10 subunit alpha0101
cytochrome P450 2C9, partial120012
ATP-dependent phosphofructokinase120012
Chain A, Putative fructose-1,6-bisphosphate aldolase4004
Chain A, HADH2 protein7007
Chain B, HADH2 protein7007
Chain A, 2-oxoglutarate Oxygenase5005
Luciferase100010
regulator of G-protein signaling 42002
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a6006
cytochrome P450 2C19 precursor5005
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 16006
vitamin D3 receptor isoform VDRA9009
Solute carrier family 22 member 1 0405
5-hydroxytryptamine receptor 1A0224
5-hydroxytryptamine receptor 2C0607
Tryptophan 5-hydroxylase 10202
5-hydroxytryptamine receptor 2A0607
D0404
D(3) dopamine receptor0202
5-hydroxytryptamine receptor 1A0505
Alpha-2B adrenergic receptor0404
D(2) dopamine receptor0202
D(1B) dopamine receptor0203
Alpha-2C adrenergic receptor0404
Alpha-2A adrenergic receptor0404
Alpha-1D adrenergic receptor0303
D(1B) dopamine receptor0101
5-hydroxytryptamine receptor 1B0505
5-hydroxytryptamine receptor 1D0202
D(4) dopamine receptor0112
5-hydroxytryptamine receptor 1F0202
5-hydroxytryptamine receptor 2B0505
5-hydroxytryptamine receptor 60202
5-hydroxytryptamine receptor 7 0404
5-hydroxytryptamine receptor 5A0202
5-hydroxytryptamine receptor 5B0202
5-hydroxytryptamine receptor 3A0202
5-hydroxytryptamine receptor 70101
D(2) dopamine receptor0527
E3 ubiquitin-protein ligase Mdm20101
D0101
5-hydroxytryptamine receptor 4 0202
D0202
5-hydroxytryptamine receptor 3B0202
GALC protein4004
Substance-P receptor0213
Neuromedin-K receptor0101
cGMP-dependent protein kinase 1 0011
Substance-P receptor0101
Chain A, Beta-lactamase6006
interleukin 87007
glp-1 receptor, partial4004
pregnane X receptor6006
67.9K protein6006
Parkin2002
arylsulfatase A4004
IDH1100010
activating transcription factor 67007
Bloom syndrome protein isoform 18008
peripheral myelin protein 22 isoform 15005
hemoglobin subunit beta2002
ras-related protein Rab-9A2002
DNA (cytosine-5)-methyltransferase 10101
Adenosine receptor A2a0101
Adenosine receptor A10101
Multidrug and toxin extrusion protein 10303
Histone-lysine N-methyltransferase EHMT20101
Replicase polyprotein 1ab0325
Replicase polyprotein 1ab0325
Integrase 0202
Chain A, Cruzipain4004
caspase-1 isoform alpha precursor4004
Caspase-73003
Inositol monophosphatase 11001
Solute carrier organic anion transporter family member 1B30608
Solute carrier organic anion transporter family member 1B10506
Kappa-type opioid receptor0405
histone-lysine N-methyltransferase 2A isoform 2 precursor2002
thioredoxin reductase8008
thioredoxin glutathione reductase2002
bromodomain adjacent to zinc finger domain 2B3003
FAD-linked sulfhydryl oxidase ALR0001
muscleblind-like protein 1 isoform 15005
Chain A, Ferritin light chain7007
15-lipoxygenase, partial4004
60 kDa chaperonin0202
60 kDa heat shock protein, mitochondrial0303
Vitamin D3 receptor0226
Glycine receptor subunit alpha-10022
Vitamin D3 receptor0011
10 kDa heat shock protein, mitochondrial0303
Thiosulfate sulfurtransferase0303
60 kDa chaperonin 0303
10 kDa chaperonin 0303
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain A, JmjC domain-containing histone demethylation protein 3A4004
hepatocyte nuclear factor 4-alpha isoform 20101
perilipin-50101
perilipin-10101
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a0101
Beta-lactamase0101
Proto-oncogene tyrosine-protein kinase Src0202
3-dehydroquinate dehydratase0011
ATP-citrate synthase 0001
Ribonuclease T0001
Cell death-related nuclease 40001
3-dehydroquinate dehydratase0011
Prolyl 4-hydroxylase0101
Alpha-ketoglutarate-dependent dioxygenase FTO0101
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain H, Fab M82G2, Heavy chain0011
Chain L, Fab M82G2, Light chain0011
Chain H, Fab M82g2, Heavy Chain0011
Chain L, Fab M82g2, Light Chain0011
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit delta0101
Amyloid-beta precursor protein1405
Fatty acid-binding protein, heart0101
Muscarinic acetylcholine receptor M20101
Muscarinic acetylcholine receptor M10112
Gamma-aminobutyric acid receptor subunit alpha-10325
Gamma-aminobutyric acid receptor subunit beta-10112
Gamma-aminobutyric acid receptor subunit gamma-20325
Liver carboxylesterase 10002
Sodium-dependent dopamine transporter0303
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
Gamma-aminobutyric acid receptor subunit beta-30213
Gamma-aminobutyric acid receptor subunit alpha-50112
Sodium-dependent serotonin transporter0304
Gamma-aminobutyric acid receptor subunit alpha-30112
Glutamate receptor ionotropic, NMDA 1 0102
Lysosomal Pro-X carboxypeptidase0101
Gamma-aminobutyric acid receptor subunit alpha-20123
Gamma-aminobutyric acid receptor subunit beta-20224
Gamma-aminobutyric acid receptor subunit alpha-40112
Gamma-aminobutyric acid receptor subunit epsilon0101
Glutamate receptor ionotropic, NMDA 2A 0102
Glutamate receptor ionotropic, NMDA 2B0102
Glutamate receptor ionotropic, NMDA 2C0102
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Leukotriene B4 receptor 10101
Gamma-aminobutyric acid receptor subunit alpha-60112
Sodium-dependent dopamine transporter0202
Glutamate receptor ionotropic, NMDA 2D0102
Gamma-aminobutyric acid receptor subunit gamma-10101
Glutamate receptor ionotropic, NMDA 3B0102
Gamma-aminobutyric acid receptor subunit gamma-30101
Leukotriene B4 receptor 20101
Glutamate receptor ionotropic, NMDA 3A0102
Gamma-aminobutyric acid receptor subunit theta0101
Transporter0505
endonuclease IV3003
PAX80001
glucocerebrosidase1001
nuclear receptor subfamily 1, group I, member 27007
nuclear receptor subfamily 0 group B member 10101
atrial natriuretic peptide receptor 2 precursor1001
steroidogenic factor 10101
neuropeptide S receptor isoform A4004
Solute carrier family 22 member 30101
Tubulin alpha-1A chain0225
Tubulin beta chain0224
Plasma kallikrein0002
Tubulin beta-4A chain0338
Tubulin beta chain0338
Tubulin alpha-3C chain0338
Serine/threonine-protein kinase pim-10101
Tubulin alpha-1B chain0338
Tubulin alpha-4A chain0338
Tubulin beta-4B chain0338
Vesicular acetylcholine transporter0101
Tubulin beta-3 chain0439
Tubulin beta-2A chain0338
Tubulin polymerization-promoting protein0011
Tubulin beta-8 chain0338
Tubulin beta-2B chain0215
Tubulin alpha-3E chain0338
Tubulin alpha-1A chain0338
Similar to alpha-tubulin isoform 1 0114
Similar to alpha-tubulin isoform 1 0103
CREB-binding protein1001
Tubulin alpha-1C chain0338
Tubulin beta-6 chain0338
Tubulin beta-2B chain0338
Tubulin beta-1 chain0338
B2 bradykinin receptor0101
Dihydrofolate reductase0204
Dihydrofolate reductase0202
Chymotrypsinogen A0102
Beta-lactamase0101
Beta-lactamase0001
Beta-galactosidase0102
Choline O-acetyltransferase0101
Ectonucleotide pyrophosphatase/phosphodiesterase family member 20202
PH domain leucine-rich repeat-containing protein phosphatase 20101
Chymotrypsin-C0101
Rap guanine nucleotide exchange factor 32002
Glutathione S-transferase P0101
Alpha-tocopherol transfer protein0011
Chain A, ATP-DEPENDENT DNA HELICASE Q12002
RAD510101
Caspase-71001
caspase-31001
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 10101
Growth factor receptor-bound protein 20101
Pantothenate synthetase0101
Discoidin domain-containing receptor 20101
Growth factor receptor-bound protein 2 0101
Reverse transcriptase/RNaseH 0338
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase0011
Chain A, STEROID DELTA-ISOMERASE0011
Steroid Delta-isomerase0011
Ileal sodium/bile acid cotransporter0101
G-protein coupled bile acid receptor 10011
Bile acid receptor0011
Thymidine kinase 2 0101
Deoxycytidine kinase0002
Probable deoxycytidylate deaminase0001
Cytidine deaminase0002
AAA family ATPase 0002
Angiotensin-converting enzyme0404
Histamine H1 receptor0113
Histamine H1 receptor0404
Histamine N-methyltransferase0001
Solute carrier family 22 member 10202
Nuclear receptor subfamily 3 group C member 3 0404
Calcium release-activated calcium channel protein 10101
Protein orai-20101
Protein orai-30101
Histamine H4 receptor0101
Histamine H3 receptor0001
Solute carrier family 22 member 20202
Serum paraoxonase/arylesterase 10202
Kinesin-like protein KIF110101
Nucleotide-binding oligomerization domain-containing protein 20202
Albumin0022
Env polyprotein 0022
Genome polyprotein 0202
UDP-glucuronosyltransferase 2B70104
Acetylcholine receptor subunit alpha0101
Acetylcholine receptor subunit beta0101
Acetylcholine receptor subunit gamma0101
Acetylcholine receptor subunit delta0101
Acetylcholine receptor subunit delta0101
Acetylcholine receptor subunit alpha0101
Acetylcholine receptor subunit gamma0101
Acetylcholine receptor subunit beta0101
Cytochrome P450 11B1, mitochondrial0101
Cytochrome P450 11B2, mitochondrial0101
UDP-glucuronosyltransferase 1A30001
Sodium/bile acid cotransporter0101
NPC1-like intracellular cholesterol transporter 10101
NPC1-like intracellular cholesterol transporter 10101
nonstructural protein 14004
serine-protein kinase ATM isoform a1001
ubiquitin carboxyl-terminal hydrolase 2 isoform a2002
M-phase phosphoprotein 83003
Fatty acid-binding protein, liver0213
Fatty acid-binding protein, liver0101
Muscarinic acetylcholine receptor M30011
Muscarinic acetylcholine receptor M40011
Muscarinic acetylcholine receptor M50011
Muscarinic acetylcholine receptor M20011
Fatty acid-binding protein, intestinal0112
Peroxisome proliferator-activated receptor alpha0011
Cruzipain0101
Peroxisome proliferator-activated receptor alpha0011
Peroxisome proliferator-activated receptor gamma0112
Peroxisome proliferator-activated receptor gamma0011
Disintegrin and metalloproteinase domain-containing protein 171001
Peroxisome proliferator-activated receptor alpha0112
Sigma non-opioid intracellular receptor 10011
Broad substrate specificity ATP-binding cassette transporter ABCG20405
Chain A, Uracil Phosphoribosyltransferase0101
Skn7p0001
Vpr2002
Solute carrier family 22 member 80001
Epidermal growth factor receptor0404
Thymidylate synthase0303
Aromatase0101
HSP40, subfamily A [Plasmodium falciparum 3D7]0001
Chain A, DEOXYNUCLEOSIDE KINASE0101
Spike glycoprotein0022
Replicase polyprotein 1ab0022
Transmembrane protease serine 20022
Procathepsin L0022
Replicase polyprotein 1a0022
Replicase polyprotein 1ab0022
Equilibrative nucleoside transporter 10101
Angiotensin-converting enzyme 2 0022
Glucagon-like peptide 1 receptor0011
Glucagon-like peptide 1 receptor0112
Glucagon receptor0011
Glucagon receptor0011
Genome polyprotein 0101
Alpha-2C adrenergic receptor0505
Alpha-1D adrenergic receptor0404
Sigma intracellular receptor 20101
Cyclic GMP-AMP synthase0101
Toll-like receptor 90101
Toll-like receptor 70101
Cytochrome P450 2C190202
Cytochrome P450 1B10101
Gonadotropin-releasing hormone receptor0202
chaperonin-containing TCP-1 beta subunit homolog1001
Synaptic vesicle glycoprotein 2A0101
dopamine D1 receptor2002
WRN1001
integrase, partial0101
lens epithelium-derived growth factor p750101
apical membrane antigen 1, AMA11001
pyruvate kinase1001
hexokinase-4 isoform 11001
atrial natriuretic peptide receptor 1 precursor1001
glucokinase regulatory protein1001
DNA polymerase eta isoform 13003
DNA polymerase iota isoform a (long)5005
Polyphenol oxidase 20001
Tyrosine-protein kinase Lck0101
Tyrosinase0101
Adenosine receptor A10001
Adenosine receptor A2a0001
Carbonic anhydrase0001
Solute carrier family 15 member 10101
Carbonic anhydrase0001
Large neutral amino acids transporter small subunit 10101
SLC16A10 protein0001
Carbonic anhydrase 0001
Carbonic anhydrase-like protein, putative0001
Carbonic anhydrase0001
Carbonic anhydrase0001
Carbonic anhydrase 0001
Monocarboxylate transporter 100001
phosphoglycerate kinase1001
Potassium channel subfamily K member 30101
Potassium channel subfamily K member 20101
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0101
Potassium voltage-gated channel subfamily A member 50101
Potassium voltage-gated channel subfamily D member 20101
Potassium channel subfamily K member 180101
PINK11001
transcriptional regulator ERG isoform 33003
Estrogen receptor0314
Glucocorticoid receptor010318
Sex hormone-binding globulin0011
Progesterone receptor0416
Glycine receptor subunit alpha-1010010
Mineralocorticoid receptor 0314
Androgen receptor0426
Androgen receptor0011
Glycine receptor subunit beta010010
Glycine receptor subunit alpha-2010010
Glycine receptor subunit alpha-3010010
Alpha-synuclein1102
Aldo-keto reductase family 1 member C30101
Aldo-keto reductase family 1 member C2 0101
Guanine nucleotide-binding protein G1001
Aldo-keto reductase family 1 member C10101
Estrogen receptor beta0314
Solute carrier family 22 member 30101
Amine oxidase [flavin-containing] B0101
Amine oxidase [flavin-containing] B0101
Synaptic vesicular amine transporter0101
Trace amine-associated receptor 10011
Trace amine-associated receptor 10011
Trace amine-associated receptor 10011
Trace amine-associated receptor 10011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
acid sphingomyelinase1001
ClpP1001
Thymidylate synthase 0101
alpha-galactosidase1001
Thymidylate synthase 0101
polyunsaturated fatty acid lipoxygenase ALOX121001
DNA polymerase beta1001
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0101
transactivating tegument protein VP16 [Human herpesvirus 1]0101
nuclear receptor coactivator 3 isoform a0101
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0203
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Tyrosine-protein kinase ABL10112
Thymidylate synthase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
High mobility group protein B10011
Dihydrofolate reductase0101
Thymidylate synthase0101
Dihydrofolate reductase0224
Glucose-6-phosphate 1-dehydrogenase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0101
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Dihydrofolate reductase0202
Histidine decarboxylase0112
Trifunctional purine biosynthetic protein adenosine-30101
Cyclin-dependent kinase 20011
Bifunctional purine biosynthesis protein ATIC0202
Multidrug resistance-associated protein 1 0001
Delta-type opioid receptor0415
Mu-type opioid receptor0415
Kappa-type opioid receptor0415
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
6-phosphogluconate dehydrogenase, decarboxylating0101
Solute carrier organic anion transporter family member 1A30001
Dihydrofolate reductase0101
Pteridine reductase 10101
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Solute carrier family 22 member 60002
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Solute carrier family 22 member 200101
Dihydrofolate reductase 0101
Solute carrier family 22 member 80002
Solute carrier family 22 member 60101
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Multidrug resistance associated protein0102
Solute carrier family 22 member 110001
Protein-arginine deiminase type-40101
Nuclear receptor subfamily 1 group I member 20022
Nuclear receptor subfamily 1 group I member 20011
Beta-2 adrenergic receptor0202
Thromboxane-A synthase 0101
Uracil nucleotide/cysteinyl leukotriene receptor0101
Mitogen-activated protein kinase 140101
Leukotriene C4 synthase0101
Cysteinyl leukotriene receptor 10101
Cysteinyl leukotriene receptor 20101
Cysteinyl leukotriene receptor 10213
5-hydroxytryptamine receptor 3E0101
5-hydroxytryptamine receptor 3B0101
Delta-type opioid receptor0214
Kappa-type opioid receptor0224
Nociceptin receptor0101
Mu-type opioid receptor0225
5-hydroxytryptamine receptor 3A0101
Mu-type opioid receptor0214
5-hydroxytryptamine receptor 3D0101
5-hydroxytryptamine receptor 3C0101
UDP-glucuronosyltransferase 1A80002
Acetylcholinesterase0101
NPC intracellular cholesterol transporter 1 precursor1001
Integrin alpha-V 0101
Botulinum neurotoxin type A 0101
Apoptosis regulator Bcl-20101
Fibroblast growth factor receptor 10101
UDP-glucuronosyltransferase 1A40102
Cholecystokinin receptor type A0202
UDP-glucuronosyltransferase 2B10 0101
Bcl-2-like protein 10101
Tyrosine-protein kinase Mer0101
Beta-tubulin 0101
beta-2 adrenergic receptor1001
lysosomal alpha-glucosidase preproprotein1001
mu-type opioid receptor isoform MOR-10011
5-hydroxytryptamine receptor 2A0011
Neuronal acetylcholine receptor subunit alpha-41001
Neuronal acetylcholine receptor subunit beta-21001
Taste receptor type 2 member 310011
Taste receptor type 2 member 600011
Sodium/potassium/calcium exchanger 40112
Taste receptor type 2 member 140011
Taste receptor type 2 member 130011
Taste receptor type 2 member 90011
Taste receptor type 2 member 40011
Sodium/potassium/calcium exchanger 20112
luciferase0001
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Corticosteroid-binding globulin0101
Glutamine synthetase0011
Nociceptin receptor0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Fatty-acid amide hydrolase 10101
Gamma-aminobutyric acid receptor subunit alpha-10001
Gamma-aminobutyric acid receptor subunit beta-10001
Gamma-aminobutyric acid receptor subunit alpha-20001
Gamma-aminobutyric acid receptor subunit alpha-30001
Gamma-aminobutyric acid receptor subunit alpha-40001
Gamma-aminobutyric acid receptor subunit gamma-20001
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent betaine transporter0101
Fatty-acid amide hydrolase 10101
Gag-Pol polyprotein0101
Reverse transcriptase 0101
Reverse transcriptase 0011
Solute carrier family 22 member 20101
Albumin0011
Beta-1 adrenergic receptor0101
5-hydroxytryptamine receptor 2C 0101
5-hydroxytryptamine receptor 70101
Alpha-1A adrenergic receptor0202
5-hydroxytryptamine receptor 2A0101
Alpha-1B adrenergic receptor0101
3-hydroxy-3-methylglutaryl-coenzyme A reductase 0101
D(2) dopamine receptor0101
5-hydroxytryptamine receptor 2B0101
Transporter0101
5-hydroxytryptamine receptor 1A0101
Multidrug and toxin extrusion protein 20101
Histamine H3 receptor0101
Cytochrome P450 3A50101
Serine/threonine-protein kinase mTOR0101
Peptidyl-prolyl cis-trans isomerase FKBP1A0213
Peptidyl-prolyl cis-trans isomerase FKBP1B0011
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform0101
Peptidyl-prolyl cis-trans isomerase FKBP50101
Splicing factor 3B subunit 30101
Adenylate kinase isoenzyme 10001
Adenylate kinase 2, mitochondrial0001
Capsid protein 0011
Chain A, ykoF0011
Chain B, ykoF0011
Chain A, ThiT0011
Thiamine transporter ThiT0011
Transketolase0011
Thiamine-binding periplasmic protein0011
Cholinesterase0101
D-alanyl-D-alanine dipeptidase0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]