| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| TDP1 protein | 6 | 0 | 0 | 6 |
| AR protein | 3 | 0 | 0 | 3 |
| glucocorticoid receptor [Homo sapiens] | 1 | 0 | 0 | 1 |
| estrogen nuclear receptor alpha | 2 | 0 | 0 | 2 |
| peroxisome proliferator activated receptor gamma | 1 | 0 | 0 | 1 |
| ATP-binding cassette sub-family C member 3 | 0 | 2 | 0 | 2 |
| Multidrug resistance-associated protein 4 | 0 | 2 | 0 | 4 |
| Bile salt export pump | 0 | 3 | 0 | 3 |
| Cellular tumor antigen p53 | 3 | 0 | 0 | 3 |
| Thromboxane-A synthase | 0 | 1 | 0 | 1 |
| Prostaglandin E2 receptor EP3 subtype | 0 | 1 | 0 | 1 |
| Prostaglandin E2 receptor EP4 subtype | 0 | 1 | 1 | 2 |
| Prostaglandin E2 receptor EP1 subtype | 0 | 1 | 0 | 1 |
| Prostacyclin receptor | 0 | 1 | 1 | 2 |
| Nuclear receptor subfamily 4 group A member 2 | 0 | 0 | 1 | 1 |
| Solute carrier organic anion transporter family member 2A1 | 0 | 0 | 0 | 1 |
| Nuclear receptor subfamily 4 group A member 2 | 0 | 0 | 1 | 1 |
| Nuclear receptor subfamily 4 group A member 2 | 0 | 0 | 1 | 1 |
| Prostaglandin E2 receptor EP2 subtype | 0 | 1 | 1 | 2 |
| Canalicular multispecific organic anion transporter 1 | 0 | 2 | 0 | 2 |
| Solute carrier organic anion transporter family member 2A1 | 0 | 0 | 0 | 1 |
| Solute carrier organic anion transporter family member 2B1 | 0 | 1 | 0 | 1 |
| Solute carrier organic anion transporter family member 3A1 | 0 | 0 | 0 | 1 |
| Phosphodiesterase | 0 | 1 | 0 | 1 |
| Multidrug resistance-associated protein 5 | 0 | 0 | 0 | 1 |
| cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 0 | 1 | 0 | 1 |
| cGMP-inhibited 3',5'-cyclic phosphodiesterase A | 0 | 1 | 0 | 1 |
| Beta-1 adrenergic receptor | 0 | 1 | 3 | 6 |
| Beta-1 adrenergic receptor | 0 | 6 | 2 | 8 |
| Chain A, Beta-lactamase | 1 | 0 | 0 | 1 |
| Fumarate hydratase | 1 | 0 | 0 | 1 |
| Smad3 | 1 | 0 | 0 | 1 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 1 | 0 | 0 | 1 |
| corticotropin-releasing hormone receptor 2 | 0 | 1 | 1 | 2 |
| nuclear receptor subfamily 1, group I, member 3 | 2 | 0 | 0 | 2 |
| EWS/FLI fusion protein | 3 | 0 | 0 | 3 |
| polyprotein | 1 | 0 | 0 | 1 |
| 67.9K protein | 2 | 0 | 0 | 2 |
| corticotropin releasing factor-binding protein | 0 | 1 | 1 | 2 |
| IDH1 | 1 | 0 | 0 | 1 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 1 | 0 | 0 | 1 |
| chromobox protein homolog 1 | 2 | 0 | 0 | 2 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform 2 | 2 | 0 | 0 | 2 |
| glycogen synthase kinase-3 beta isoform 1 | 0 | 0 | 2 | 2 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 3 | 0 | 0 | 3 |
| urokinase-type plasminogen activator precursor | 2 | 0 | 0 | 2 |
| plasminogen precursor | 2 | 0 | 0 | 2 |
| urokinase plasminogen activator surface receptor precursor | 2 | 0 | 0 | 2 |
| geminin | 4 | 0 | 0 | 4 |
| lamin isoform A-delta10 | 2 | 0 | 0 | 2 |
| 5'-nucleotidase | 0 | 1 | 0 | 1 |
| Adenosine receptor A3 | 0 | 1 | 0 | 1 |
| Adenosine deaminase | 0 | 0 | 0 | 2 |
| glp-1 receptor, partial | 1 | 0 | 0 | 1 |
| thioredoxin reductase | 3 | 0 | 0 | 3 |
| phosphopantetheinyl transferase | 1 | 0 | 0 | 1 |
| GLS protein | 1 | 0 | 0 | 1 |
| GLI family zinc finger 3 | 2 | 0 | 0 | 2 |
| Microtubule-associated protein tau | 1 | 0 | 0 | 1 |
| regulator of G-protein signaling 4 | 1 | 0 | 0 | 1 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 2 | 0 | 0 | 2 |
| estrogen-related nuclear receptor alpha | 1 | 0 | 0 | 1 |
| NPYLR7B | 0 | 0 | 1 | 1 |
| cytochrome P450 2D6 | 1 | 0 | 0 | 1 |
| euchromatic histone-lysine N-methyltransferase 2 | 3 | 0 | 0 | 3 |
| thyroid stimulating hormone receptor | 1 | 0 | 0 | 1 |
| activating transcription factor 6 | 1 | 0 | 0 | 1 |
| Histone H2A.x | 1 | 0 | 0 | 1 |
| beta-2 adrenergic receptor | 1 | 0 | 0 | 1 |
| hexokinase-4 isoform 1 | 1 | 0 | 0 | 1 |
| vitamin D3 receptor isoform VDRA | 1 | 0 | 0 | 1 |
| glucokinase regulatory protein | 1 | 0 | 0 | 1 |
| serine/threonine-protein kinase mTOR isoform 1 | 1 | 0 | 0 | 1 |
| peripheral myelin protein 22 | 2 | 0 | 0 | 2 |
| Bile salt export pump | 0 | 2 | 0 | 2 |
| Beta-2 adrenergic receptor | 0 | 4 | 3 | 8 |
| Beta-2 adrenergic receptor | 0 | 4 | 1 | 6 |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | 0 | 1 | 0 | 1 |
| Beta-3 adrenergic receptor | 0 | 3 | 2 | 5 |
| D(2) dopamine receptor | 0 | 2 | 1 | 3 |
| Alpha-1B adrenergic receptor | 0 | 3 | 1 | 4 |
| Beta-1 adrenergic receptor | 0 | 4 | 2 | 8 |
| Beta-2 adrenergic receptor | 0 | 0 | 1 | 1 |
| Alpha-2B adrenergic receptor | 0 | 2 | 1 | 3 |
| D(1A) dopamine receptor | 0 | 2 | 1 | 3 |
| D(4) dopamine receptor | 0 | 1 | 0 | 1 |
| Alpha-2C adrenergic receptor | 0 | 2 | 1 | 3 |
| Alpha-2A adrenergic receptor | 0 | 2 | 1 | 3 |
| Alpha-1D adrenergic receptor | 0 | 3 | 1 | 4 |
| Beta-adrenergic receptor kinase 1 | 0 | 0 | 1 | 1 |
| Alpha-1D adrenergic receptor | 0 | 0 | 2 | 3 |
| Beta-3 adrenergic receptor | 0 | 0 | 1 | 1 |
| Beta-3 adrenergic receptor | 0 | 3 | 1 | 4 |
| Vasopressin V1a receptor | 0 | 0 | 1 | 1 |
| Beta-1 adrenergic receptor | 0 | 2 | 1 | 3 |
| Alpha-1A adrenergic receptor | 0 | 1 | 3 | 5 |
| Alpha-1B adrenergic receptor | 0 | 0 | 2 | 3 |
| Glutamate receptor ionotropic, NMDA 1 | 0 | 0 | 1 | 1 |
| D(3) dopamine receptor | 0 | 1 | 0 | 1 |
| Alpha-1A adrenergic receptor | 0 | 3 | 1 | 4 |
| Histamine H2 receptor | 1 | 0 | 1 | 2 |
| D(1A) dopamine receptor | 1 | 0 | 0 | 1 |
| Beta-2 adrenergic receptor | 0 | 2 | 0 | 2 |
| Taste receptor type 2 member 38 | 0 | 0 | 1 | 1 |
| Taste receptor type 2 member 39 | 0 | 0 | 1 | 1 |
| Taste receptor type 2 member 40 | 0 | 0 | 1 | 1 |
| Taste receptor type 2 member 41 | 0 | 0 | 1 | 1 |
| Taste receptor type 2 member 43 | 0 | 0 | 1 | 1 |
| Taste receptor type 2 member 31 | 0 | 0 | 1 | 1 |
| Taste receptor type 2 member 45 | 0 | 0 | 1 | 1 |
| Taste receptor type 2 member 46 | 0 | 0 | 1 | 1 |
| Taste receptor type 2 member 30 | 0 | 0 | 1 | 1 |
| Taste receptor type 2 member 19 | 0 | 0 | 1 | 1 |
| Taste receptor type 2 member 20 | 0 | 0 | 1 | 1 |
| Taste receptor type 2 member 50 | 0 | 0 | 1 | 1 |
| Taste receptor type 2 member 60 | 0 | 0 | 1 | 1 |
| Oxytocin receptor | 0 | 0 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2A | 0 | 0 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2B | 0 | 0 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2C | 0 | 0 | 1 | 1 |
| Beta-2 adrenergic receptor | 0 | 1 | 1 | 2 |
| Glutamate receptor ionotropic, NMDA 2D | 0 | 0 | 1 | 1 |
| Taste receptor type 2 member 42 | 0 | 0 | 1 | 1 |
| Beta-2 adrenergic receptor | 0 | 1 | 3 | 5 |
| Glutamate receptor ionotropic, NMDA 3B | 0 | 0 | 1 | 1 |
| Taste receptor type 2 member 16 | 0 | 0 | 1 | 1 |
| Taste receptor type 2 member 14 | 0 | 0 | 1 | 1 |
| Taste receptor type 2 member 13 | 0 | 0 | 1 | 1 |
| Taste receptor type 2 member 10 | 0 | 0 | 1 | 1 |
| Taste receptor type 2 member 9 | 0 | 0 | 1 | 1 |
| Taste receptor type 2 member 8 | 0 | 0 | 1 | 1 |
| Taste receptor type 2 member 7 | 0 | 0 | 1 | 1 |
| Taste receptor type 2 member 5 | 0 | 0 | 1 | 1 |
| Taste receptor type 2 member 4 | 0 | 0 | 1 | 1 |
| Taste receptor type 2 member 3 | 0 | 0 | 1 | 1 |
| Taste receptor type 2 member 1 | 0 | 0 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3A | 0 | 0 | 1 | 1 |
| 2,3-bisphosphoglycerate-independent phosphoglycerate mutase | 1 | 0 | 0 | 1 |
| ATP-dependent phosphofructokinase | 2 | 0 | 0 | 2 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | 1 | 0 | 0 | 1 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | 1 | 0 | 0 | 1 |
| Chain A, 2-oxoglutarate Oxygenase | 1 | 0 | 0 | 1 |
| endonuclease IV | 1 | 0 | 0 | 1 |
| 15-lipoxygenase, partial | 1 | 0 | 0 | 1 |
| RAR-related orphan receptor gamma | 1 | 0 | 0 | 1 |
| USP1 protein, partial | 1 | 0 | 0 | 1 |
| GALC protein | 1 | 0 | 0 | 1 |
| thyroid stimulating hormone receptor | 1 | 0 | 0 | 1 |
| estrogen receptor 2 (ER beta) | 1 | 0 | 0 | 1 |
| nonstructural protein 1 | 1 | 0 | 0 | 1 |
| peroxisome proliferator-activated receptor delta | 1 | 0 | 0 | 1 |
| arylsulfatase A | 2 | 0 | 0 | 2 |
| Bloom syndrome protein isoform 1 | 1 | 0 | 0 | 1 |
| peripheral myelin protein 22 isoform 1 | 1 | 0 | 0 | 1 |
| cytochrome P450 2C19 precursor | 1 | 0 | 0 | 1 |
| potassium voltage-gated channel subfamily H member 2 isoform d | 1 | 0 | 0 | 1 |
| flap endonuclease 1 | 1 | 0 | 0 | 1 |
| M-phase phosphoprotein 8 | 1 | 0 | 0 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | 1 | 0 | 0 | 1 |
| Spike glycoprotein | 1 | 0 | 0 | 1 |
| ATPase family AAA domain-containing protein 5 | 1 | 0 | 0 | 1 |
| Ataxin-2 | 2 | 0 | 0 | 2 |
| D(1A) dopamine receptor | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | 0 | 1 | 1 | 2 |
| Solute carrier family 22 member 1 | 0 | 1 | 0 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 4 | 0 | 2 | 0 | 2 |
| Albumin | 0 | 0 | 1 | 1 |
| Cytochrome P450 1A2 | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M2 | 0 | 1 | 1 | 2 |
| ATP-dependent translocase ABCB1 | 0 | 2 | 0 | 2 |
| Cytochrome P450 3A4 | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 1A | 0 | 1 | 0 | 1 |
| Alpha-2A adrenergic receptor | 0 | 1 | 2 | 4 |
| Adenosine receptor A3 | 0 | 1 | 1 | 2 |
| Cytochrome P450 2C8 | 0 | 1 | 0 | 1 |
| Cytochrome P450 2D6 | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M1 | 0 | 1 | 1 | 2 |
| Cytochrome P450 2C9 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 0 | 1 | 1 | 2 |
| Alpha-2B adrenergic receptor | 0 | 0 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit delta | 0 | 1 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 0 | 1 | 1 | 2 |
| Alpha-2C adrenergic receptor | 0 | 1 | 2 | 4 |
| D(3) dopamine receptor | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 1A | 0 | 2 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 0 | 1 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 0 | 1 | 1 | 2 |
| Muscarinic acetylcholine receptor M3 | 0 | 1 | 1 | 2 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 0 | 1 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 0 | 1 | 1 | 2 |
| Endothelin-1 receptor | 0 | 1 | 1 | 2 |
| 5-hydroxytryptamine receptor 1B | 0 | 2 | 1 | 3 |
| 5-hydroxytryptamine receptor 2A | 0 | 2 | 1 | 3 |
| 5-hydroxytryptamine receptor 2C | 0 | 2 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 0 | 1 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 0 | 1 | 1 | 2 |
| 5-hydroxytryptamine receptor 1B | 0 | 2 | 0 | 2 |
| Adenosine receptor A2a | 0 | 1 | 1 | 2 |
| Neuromedin-K receptor | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 0 | 1 | 1 | 2 |
| Type-1 angiotensin II receptor | 0 | 1 | 1 | 2 |
| Sodium-dependent serotonin transporter | 0 | 2 | 0 | 2 |
| Cholecystokinin receptor type A | 0 | 1 | 1 | 2 |
| Cytochrome P450 2C19 | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 7 | 0 | 1 | 1 | 2 |
| Mu-type opioid receptor | 0 | 1 | 1 | 2 |
| Vasopressin V1a receptor | 0 | 1 | 1 | 2 |
| Delta-type opioid receptor | 0 | 1 | 1 | 2 |
| Kappa-type opioid receptor | 0 | 1 | 1 | 2 |
| 5-hydroxytryptamine receptor 2B | 0 | 2 | 1 | 3 |
| 5-hydroxytryptamine receptor 6 | 0 | 2 | 1 | 3 |
| 5-hydroxytryptamine receptor 7 | 0 | 1 | 0 | 1 |
| Cytochrome P450 2J2 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 0 | 1 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 0 | 1 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 0 | 1 | 1 | 2 |
| Potassium voltage-gated channel subfamily H member 2 | 0 | 1 | 0 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | 0 | 1 | 0 | 1 |
| Sodium channel protein type 5 subunit alpha | 0 | 1 | 0 | 1 |
| Sodium/bile acid cotransporter | 0 | 1 | 0 | 1 |
| GABA theta subunit | 0 | 1 | 1 | 2 |
| Sigma non-opioid intracellular receptor 1 | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit epsilon | 0 | 1 | 1 | 2 |
| Nuclear receptor subfamily 2 group E member 1 | 0 | 0 | 2 | 2 |
| Thymidine kinase, cytosolic | 0 | 0 | 0 | 1 |
| Dipeptidyl peptidase 4 | 0 | 1 | 0 | 1 |
| Histamine H1 receptor | 0 | 0 | 1 | 1 |
| Adenosylhomocysteinase | 0 | 1 | 0 | 1 |
| RNA-directed RNA polymerase | 0 | 1 | 1 | 2 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |