Hypertension, Essential

Synonym
Hypertension, Essential

Excerpt	Reference
"Essential hypertension is one of the major contributors to premature morbidity and mortality due to the incresased risk for coronary heart disease, stroke, renal disease, peripheral vascular disease and vascular dementia for both men and women."	( Arias de Saavedra-Alías, JM; Liébana-Cañada, A; Martínez-Martos, JM; Ramírez-Expósito, MJ; Sánchez-Agesta Ortega, R; Sánchez-Muñoz, B, 2013)
"Essential hypertension is associated with an exaggerated natriuresis in response to intravenous infusion of isotonic saline."	( Frøkiær, J; Thomsen, K; Wang, G, 2013)
"Essential hypertension is a complex, polygenic disease derived from the interaction of patient's genetic background with the environment."	( Argiolas, G; Barlassina, C; Boerwinkle, E; Braga, D; Carpini, SD; Chapman, AB; Chittani, M; Citterio, L; Condorelli, G; Cooper-Dehoff, RM; Cusi, D; Dominiczak, AF; Donner, KM; Frau, F; Fresu, G; Glorioso, N; Glorioso, V; Gong, Y; Hiltunen, TP; Johnson, JA; Kontula, KK; Lanzani, C; Manunta, P; Melander, O; Ortu, MF; Padmanabhan, S; Piras, DA; Pozzoli, S; Rivera, NV; Salvi, E; Simonini, M; Trimarco, B; Troffa, C; Turner, ST; Velayutham, D; Zaninello, R, 2015)
"Essential hypertension is associated with impaired mental stress-induced nNOS-mediated vasodilator responses; this may relate to increased sympathetic outflow in hypertension."	( Brett, SE; Chowienczyk, PJ; Fok, HW; Geer, A; Khan, SG; Shabeeh, H; Shah, AM, 2015)
"Essential hypertension is a chronic pathology that causes long-term complications due to late diagnosis of patients, the inability to control the disease through medication, or due to the complexity of associated risk factors."	( Buda, V; Cristescu, C; Suciu, L; Tomescu, MC; Topîrceanu, A; Udrescu, L; Udrescu, M, 2016)
"Essential hypertension is a complex clinical condition, characterized by multiple and concomitant abnormal activation of different regulatory and contra-regulatory pathophysiological mechanisms, leading to sustained increase of blood pressure (BP) levels."	( Acone, B; Calcullo, C; Crippa, M; De Luca, N; Desideri, G; Gaudio, GV; Lonati, LM; Orselli, L; Roca, E; Scuteri, A; Tocci, G; Vulpis, V; Zaninelli, A, 2018)
"Essential hypertension is the leading cause of premature death worldwide."	( Carlisle, RE; Dickhout, JG; Lu, C; Naiel, S; Tat, V, 2019)
"Essential hypertension is considered to be a result of the interaction between genetic and environmental factors, including perinatal factors."	( Burgueño, AL; Mensegue, MF; Tellechea, ML, 2020)
"Essential hypertension is a multifactorial disease, which is affected by genetic and environmental factors, and can cause diseases such as cerebrovascular disease, heart failure, coronary heart disease, and chronic renal failure."	( Cai, W; Jiang, X; Lang, M; Lei, J; Yu, Q; Zhang, X; Zhou, C; Zou, W, 2020)
"Essential hypertension is a pivotal risk factor for the development of cardiovascular disease (CVD)."	( Ehlert, U; Gideon, A; Sauter, C; von Känel, R; Wirtz, PH, 2021)
"Essential hypertension is a major disease, mostly with unknown underlying mechanisms."	( Brem, AS; Morris, DJ; Odermatt, A, 2021)
"Essential hypertension is a condition characterized by a rise in blood pressure of undetermined cause, includes 90% of all hypertensive cases and is a highly important public health challenge with major modifiable cause of morbidity and mortality."	( Haile, K; Timerga, A, 2021)
"Plateau essential hypertension is a common chronic harmful disease of permanent residents in plateau areas."	( Hu, X; Jia, Z; Li, Z; Song, C; Tian, L; Wan, J; Wu, X; Yan, C; Yang, J, 2022)
"Essential hypertension is caused by the interaction of genetic, behavioral, and environmental factors."	( Armando, I; Jose, PA; Yang, J; Zeng, C, 2023)

Excerpt	Reference
"Essential hypertension has been regarded a significant risk factor for cardiovascular disease across the globe, and a significant escapable causation of early death as well as morbidity in the U."	( Dai, GY; Zhu, YH, 2022)

Excerpt	Reference
"In 198 patients with untreated essential hypertension free of clinically relevant cardiovascular complications, we measured plasma levels of fibrinogen, prothrombin fragment 1 + 2, D-dimer, plasminogen activator inhibitor-1, and tissue plasminogen activator, and performed conventional echocardiography and TDI."	( Catena, C; Colussi, G; Fedrizzi, S; Sechi, LA, 2013)
"A total of 182 individuals with never-treated essential hypertension and 182 age-matched healthy controls were studied."	( Wang, X; Xia, W; Xu, L; Xu, W; Yao, Y, 2015)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	284 (33.81)	23.3326
1990's	1 (0.12)	12.5806
2000's	0 (0.00)	18.1394
2010's	412 (49.05)	28.8240
2020's	143 (17.02)	9.53

Drug	Relationship Strength	Studies	Trials
adenine	low	2	0
bromide	low	1	0
carbamates	low	3	0
carbon monoxide	low	1	0
carnitine	low	1	0
catechol	low	2	0
chlorine	low	4	0
hydrogen sulfide	low	3	0
n(g),n(g')-dimethyl-l-arginine	low	2	0
creatine	low	1	0
lactic acid	low	2	0
hydrogen carbonate	low	2	0
histamine	low	1	0
iodine	low	3	0
dihydroxyphenylalanine	low	3	0
thioctic acid	medium	1	1
inositol	low	1	0
melatonin	medium	4	3
niacin	medium	2	1
nitrates	low	1	0
nitrites	low	3	0
4-aminobenzoic acid	low	1	0
phthalic acid	low	1	0
taurine	low	1	0
uric acid	medium	37	3
urea	low	2	0
vanillin	low	1	0
normetanephrine	low	4	0
vanilmandelic acid	low	1	0
menthol	low	1	0
mandelic acid	low	4	0
1-anilino-8-naphthalenesulfonate	low	2	0
acetazolamide	low	4	0
am 251	low	1	0
p-aminohippuric acid	low	2	0
theophylline	low	3	0
amlodipine	medium	62	44
aranidipine	medium	2	2
arotinolol	medium	1	1
aspirin	low	1	0
atenolol	medium	4	3
bamethan	low	1	0
bendroflumethiazide	medium	2	1
benzbromarone	medium	1	1
benzothiazide	low	1	0
bisoprolol	medium	7	4
candesartan cilexetil	medium	3	2
candesartan	medium	10	5
carvedilol	medium	4	1
chlorothiazide	low	26	0
chlorpromazine	low	3	0
chlorthalidone	medium	12	6
diazoxide	low	1	0
doxazosin	medium	1	1
felodipine	medium	3	3
fluconazole	low	1	0
guaifenesin	medium	1	1
guanethidine	low	14	0
hexamethonium	low	13	0
hydralazine	low	19	0
hydrochlorothiazide	medium	37	22
lidocaine	medium	2	2
indapamide	medium	13	7
iohexol	low	1	0
avapro	medium	6	3
isoproterenol	medium	1	1
ketamine	low	1	0
labetalol	low	1	0
losartan	medium	19	14
mecamylamine	low	1	0
meprobamate	low	1	0
metformin	low	1	0
methyclothiazide	low	4	0
metoprolol	medium	5	2
nicardipine	low	2	0
nifedipine	medium	12	8
nitroglycerin	low	4	0
omeprazole	low	1	0
oxybutynin	medium	1	1
pargyline	low	2	0
pentoxifylline	medium	1	1
phenoxybenzamine	low	1	0
4-phenylbutyric acid	low	1	0
phenylbutazone	low	1	0
moxonidine	medium	1	1
prazosin	medium	1	1
procaine	low	1	0
propranolol	low	1	0
terazosin	medium	1	1
trichlormethiazide	medium	4	2
tyramine	low	2	0
corticosterone	low	2	0
prednisolone	low	1	0
reserpine	low	34	0
phentolamine	medium	4	1
thymidine	low	1	0
thyroxine	low	2	0
spironolactone	medium	7	1
aldosterone	medium	96	4
pentolinium tartrate	low	2	0
pheniprazine	low	1	0
desoxycorticosterone acetate	low	1	0
adenosine diphosphate	low	1	0
tyrosine	low	2	0
adenosine monophosphate	low	1	0
bretylium tosylate	low	2	0
methacholine chloride	low	1	0
methionine	low	1	0
desoxycorticosterone	medium	2	1
colchicine	medium	1	1
mannitol	low	1	0
histidine	low	1	0
valine	medium	8	4
quinethazone	low	1	0
arginine	medium	7	2
propane	low	1	0
tert-butylamine	medium	1	1
syrosingopine	low	1	0
synephrine	low	1	0
pyrroles	medium	4	2
thiophenes	low	1	0
ergotamine	low	1	0
deserpidine	low	1	0
iodohippuric acid	low	1	0
quinazolines	low	1	0
cyclopentane	low	1	0
ephedrine	low	1	0
hydrazine	low	2	0
thiocyanate	low	3	0
fluorobenzenes	medium	1	1
dihydralazine	low	1	0
kainic acid	low	1	0
malondialdehyde	low	4	0
dehydroepiandrosterone sulfate	low	1	0
canrenone	medium	1	1
d-alpha tocopherol	medium	3	1
amiloride	medium	1	1
azetidyl-2-carboxylic acid	medium	4	3
metanephrine	low	5	0
trimethaphan	low	1	0
cadmium	low	1	0
gadolinium	low	1	0
magnesium sulfate	medium	1	1
trolamine salicylate	low	1	0
camphidonium	low	1	0
clemastine	low	1	0
fluorides	low	1	0
fludrocortisone	low	1	0
glutamic acid	low	1	0
dobutamine	low	1	0
methyldopa	low	7	0
ng-nitroarginine methyl ester	low	1	0
captopril	medium	5	1
fomesafen	low	2	0
quinapril	low	1	0
itraconazole	low	1	0
atorvastatin	medium	2	1
valsartan	medium	27	17
adenosine	low	1	0
tetrahydrocorticosterone	low	1	0
lercanidipine	medium	6	2
azelnidipine	medium	4	3
iobitridol	low	1	0
telmisartan	medium	14	8
nicotine	low	1	0
fibrinogen	low	5	0
homocysteine	low	15	0
zofenopril	low	1	0
tetrahydrodeoxycorticosterone	low	1	0
1,4-dihydropyridine	low	1	0
perindopril	medium	19	10
chymosin	low	2	0
efonidipine	medium	1	1
tetrahydroaldosterone	low	1	0
angiotensin ii, des-phe(8)-	low	3	0
n,n-dimethylarginine	low	2	0
olmesartan medoxomil	medium	2	2
omega-n-methylarginine	low	1	0
ezetimibe	medium	2	1
olmesartan	medium	19	13
dihydroergocornine	low	1	0
symmetric dimethylarginine	low	1	0
angiotensin ii	medium	24	2
atropine	low	1	0
cortisone	low	2	0
3-nitrotyrosine	low	1	0
sodium sulfide	low	1	0
potassium bromide	low	1	0
dihydropyridines	medium	16	9
fibrin	low	2	0
bradykinin	low	2	0
ouabain	low	1	0
inositol 3-phosphate	low	1	0
trimethaphan camsylate	low	1	0
mepirodipine	low	1	0
eplerenone	medium	3	2
ergonovine	low	3	0
tretinoin	low	1	0
arachidonic acid	low	1	0
retinol	low	2	0
oleic acid	low	1	0
mln 4760	low	1	0
potassium thiocyanate	low	3	0
potassium acetate	low	1	0
glycosides	low	1	0
isomethyleugenol	low	1	0
cannabidiol	medium	1	1
arginine vasopressin	low	1	0
benidipine	medium	1	1
prednisolone hemisuccinate	low	1	0
urb 597	low	1	0
tocopherylquinone	low	1	0
orlistat	low	1	0
pd 168,077	low	1	0
17-ketosteroids	low	2	0
naphthoquinones	low	1	0
osteoprotegerin	medium	1	1
bilirubin	low	2	0
dinoprost	low	2	0
vitamin k semiquinone radical	low	1	0
thromboxane a2	low	1	0
cholecalciferol	low	2	0
rutin	low	1	0
rescinnamine	low	1	0
eprosartan	low	1	0
anandamide	low	1	0
8-epi-prostaglandin f2alpha	low	2	0
iodopyracet	low	1	0
arachidonyl-2-chloroethylamide	low	1	0
dexmedetomidine	medium	1	1
lacidipine	low	1	0
11-dehydrocorticosterone	low	1	0
ag-490	medium	1	1
arsenic	low	1	0
lisinopril	medium	6	1
benazepril	low	1	0
veratrine	low	1	0
enalapril	medium	10	2
fumarates	medium	3	1
phosphorus	low	4	0
aliskiren	medium	3	1
am-356	low	1	0
beta-escin	low	1	0
1-aminocyclopentane-1,3,4-tricarboxylic acid	low	1	0
sacubitril	medium	6	3
levamlodipine	medium	1	1
mocetinostat	low	2	0
fimasartan	medium	8	8
angiotensin amide	low	3	0
oxadiazoles	medium	12	11
amlodipine, valsartan drug combination	medium	2	2
losartan potassium	low	3	0
marinobufagenin	medium	1	1
pituitrin	low	3	0
enerbol	low	1	0
icatibant	low	1	0
cosyntropin	low	1	0
atrial natriuretic factor	low	6	0
angiotensinogen	medium	10	1
endothelin-1	medium	7	1
sodium nitrite	medium	1	1
sodium ethylxanthate	low	1	0
allisartan isoproxil	medium	4	3
fps-zm1	low	1	0
preminent	low	1	0
canagliflozin	low	1	0
egg white	low	1	0
cardiovascular agents	low	13	0
osilodrostat	medium	1	1
piperidines	low	1	0
18-hydroxycortisol	low	1	0
interleukin-8	low	2	0
fosinopril	low	2	0
natriuretic peptide, brain	low	9	0
ascorbic acid	medium	5	1
indapamide, perindopril drug combination	medium	2	1
epidermal growth factor	low	1	0
calca protein, human	low	1	0
nitrophenols	medium	1	1
angiotensin i	low	4	0
adrenomedullin	low	5	0
nephrin	medium	1	1
thromboplastin	low	2	0
exudates	low	5	0
cyclic gmp	low	2	0
deoxyguanosine	low	2	0
guanine	low	1	0
folic acid	low	1	0
neopterin	low	1	0
rifampin	low	2	0
allopurinol	medium	4	2
tak 491	medium	4	4
sildenafil citrate	medium	1	1
azilsartan	medium	8	7
8-hydroxy-2'-deoxyguanosine	low	3	0
eye	low	2	0
leptin	medium	7	1

Protein Targets (1,767)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Cytochrome P450 2C9	0	29	2	31
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	44	0	0	44
phosphopantetheinyl transferase	34	0	0	34
USP1 protein, partial	45	0	0	45
TDP1 protein	74	0	0	74
regulator of G-protein signaling 4	31	0	0	31
cytochrome P450 2D6 isoform 1	19	0	0	19
cytochrome P450 2C19 precursor	19	0	0	19
cytochrome P450 2C9 precursor	13	0	0	13
Metabotropic glutamate receptor 8	0	2	1	3
Metabotropic glutamate receptor 6	0	1	4	6
Metabotropic glutamate receptor 1	0	3	1	4
Metabotropic glutamate receptor 2	0	1	2	3
Metabotropic glutamate receptor 4	0	1	2	3
Metabotropic glutamate receptor 5	0	1	3	4
Metabotropic glutamate receptor 6	0	0	2	2
Metabotropic glutamate receptor 7	0	0	2	2
Histamine H2 receptor	22	0	2	25
Metabotropic glutamate receptor 8	0	1	2	3
Metabotropic glutamate receptor 1	0	1	2	5
Metabotropic glutamate receptor 2	0	1	2	5
Metabotropic glutamate receptor 7	0	1	2	4
Metabotropic glutamate receptor 4	0	1	2	5
Chain B, pheromone binding protein	0	0	1	1
Chain A, pheromone binding protein	0	0	1	1
Chain A, JmjC domain-containing histone demethylation protein 3A	15	0	0	15
Chain A, RNA-directed RNA polymerase NS5	0	1	0	1
acid sphingomyelinase	7	0	0	7
thioredoxin reductase	49	0	0	49
vitamin D3 receptor isoform VDRA	28	0	0	28
importin subunit beta-1 isoform 1	13	0	0	13
flap endonuclease 1	22	0	0	22
serine/threonine-protein kinase PLK1	6	0	0	6
snurportin-1	13	0	0	13
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	12	0	0	12
GTP-binding nuclear protein Ran isoform 1	10	0	0	10
DNA polymerase eta isoform 1	7	0	0	7
DNA polymerase iota isoform a (long)	25	0	0	25
urokinase-type plasminogen activator precursor	7	0	0	7
plasminogen precursor	7	0	0	7
urokinase plasminogen activator surface receptor precursor	7	0	0	7
geminin	66	0	0	66
DNA polymerase kappa isoform 1	31	0	0	31
fibroblast growth factor 22 isoform 1 precursor	0	0	0	1
Mitogen-activated protein kinase 13	0	1	0	1
Beta-lactamase	0	4	0	4
Transthyretin	0	1	1	3
Fatty acid-binding protein, intestinal	0	1	1	2
Fatty acid-binding protein, adipocyte	0	4	2	6
Cyclin-A2	0	1	0	1
Cannabinoid receptor 1	0	5	3	8
Cyclin-dependent kinase 2	0	2	1	3
Choline O-acetyltransferase	0	2	0	2
Mitogen-activated protein kinase 12	0	1	0	1
Guanine nucleotide-binding protein G	7	0	0	7
Fatty acid-binding protein 5	0	2	1	3
Fatty acid-binding protein 5	0	0	3	3
Mitogen-activated protein kinase 11	0	1	0	1
Mitogen-activated protein kinase 14	0	4	0	4
Chain A, Putative fructose-1,6-bisphosphate aldolase	14	0	0	14
bromodomain adjacent to zinc finger domain 2B	19	0	0	19
euchromatic histone-lysine N-methyltransferase 2	86	0	0	86
pyruvate kinase PKM isoform a	3	0	0	3
Glycoprotein hormones alpha chain	1	0	0	1
Tubulin--tyrosine ligase	0	2	0	2
Genome polyprotein	0	0	1	1
AR protein	77	0	0	77
thyroid stimulating hormone receptor	27	0	0	27
glucocorticoid receptor [Homo sapiens]	66	0	0	66
retinoic acid nuclear receptor alpha variant 1	51	0	0	51
estrogen nuclear receptor alpha	89	0	0	89
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	37	0	0	37
Histone H2A.x	22	0	0	22
chromobox protein homolog 1	45	0	0	45
transcriptional regulator ERG isoform 3	7	0	0	7
Polyphenol oxidase 2	0	7	0	10
Cellular tumor antigen p53	52	0	0	52
Thiopurine S-methyltransferase	0	1	0	1
Succinate-semialdehyde dehydrogenase, mitochondrial	0	2	0	2
4-aminobutyrate aminotransferase, mitochondrial	0	2	0	2
Cytochrome P450 1B1	0	7	1	8
Dihydropteroate synthase	0	0	1	1
Chain A, Cruzipain	16	0	0	16
RAR-related orphan receptor gamma	58	0	0	58
Microtubule-associated protein tau	36	0	0	36
aldehyde dehydrogenase 1 family, member A1	53	0	0	53
estrogen receptor 2 (ER beta)	30	0	0	30
cytochrome P450 family 3 subfamily A polypeptide 4	56	0	0	56
cytochrome P450 2D6	32	0	0	32
glucocerebrosidase	14	0	0	14
IDH1	28	0	0	28
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	21	0	0	21
thyroid hormone receptor beta isoform 2	44	0	0	44
mitogen-activated protein kinase 1	24	0	0	24
peripheral myelin protein 22	32	0	0	32
survival motor neuron protein isoform d	31	0	0	31
lethal factor (plasmid)	18	0	0	18
lamin isoform A-delta10	62	0	0	62
Potassium channel subfamily K member 2	0	4	4	8
Rap guanine nucleotide exchange factor 3	13	0	0	13
Potassium voltage-gated channel subfamily A member 3	0	0	1	1
Acetylcholinesterase	0	1	0	1
Pteridine reductase 1	0	1	0	1
Potassium voltage-gated channel subfamily A member 1	0	2	1	3
Potassium voltage-gated channel subfamily H member 2	0	22	0	22
ATP-dependent phosphofructokinase	31	0	0	31
5-hydroxytryptamine receptor 2C	0	5	2	7
5-hydroxytryptamine receptor 2A	0	6	3	9
5-hydroxytryptamine receptor 1A	0	23	5	29
5-hydroxytryptamine receptor 1B	0	16	2	18
5-hydroxytryptamine receptor 1D	0	2	2	4
5-hydroxytryptamine receptor 1F	0	2	2	4
5-hydroxytryptamine receptor 2B	0	4	2	6
5-hydroxytryptamine receptor 6	0	0	2	2
Sodium-dependent serotonin transporter	0	10	1	11
Sodium-dependent serotonin transporter	0	5	0	5
5-hydroxytryptamine receptor 7	0	1	2	3
5-hydroxytryptamine receptor 5A	0	0	2	2
5-hydroxytryptamine receptor 5B	0	0	2	2
5-hydroxytryptamine receptor 3A	0	0	2	2
5-hydroxytryptamine receptor 4	0	0	2	2
5-hydroxytryptamine receptor 3B	0	0	2	2
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Histone deacetylase 3	0	5	0	5
Histone deacetylase 4	0	4	0	4
Histone deacetylase 1	0	6	0	6
Histone deacetylase 7	0	4	0	4
Histone deacetylase 2	0	6	0	6
Polyamine deacetylase HDAC10	0	2	0	2
Histone deacetylase 11	0	3	0	3
Histone deacetylase 8	0	4	0	4
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
Histone deacetylase 6	0	5	0	5
Histone deacetylase 9	0	3	0	3
Histone deacetylase 5	0	4	0	4
Chain A, Avidin	0	0	2	2
Chain A, Avidin	0	0	2	2
Chain B, Avidin	0	0	2	2
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	29	0	0	29
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Beta-lactamase	28	0	0	28
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Class Iii Chitinase Chia1	0	1	0	1
Chain A, Carbonic anhydrase 13	0	1	0	1
Chain A, Carbonic anhydrase II	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase	0	1	0	1
Chain B, Carbonic anhydrase	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	3	0	3
GALC protein	14	0	0	14
GLI family zinc finger 3	58	0	0	58
nuclear receptor subfamily 1, group I, member 3	40	0	0	40
retinoid X nuclear receptor alpha	40	0	0	40
estrogen-related nuclear receptor alpha	61	0	0	61
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	2	0	2
arylsulfatase A	29	0	0	29
Carbonic anhydrase	0	2	0	2
Bloom syndrome protein isoform 1	29	0	0	29
thyroid hormone receptor beta isoform a	15	0	0	15
nuclear factor erythroid 2-related factor 2 isoform 1	53	0	0	53
muscleblind-like protein 1 isoform 1	10	0	0	10
Gamma-aminobutyric acid receptor subunit pi	38	3	3	44
ATP-binding cassette sub-family C member 3	0	52	0	52
Multidrug resistance-associated protein 4	0	53	0	56
Carbonic anhydrase	0	1	0	1
Solute carrier family 22 member 6	0	3	0	4
Carbonic anhydrase 12	0	10	2	21
Prolyl endopeptidase	0	1	0	1
Carbonic anhydrase-related protein 11	0	1	0	2
Bile salt export pump	0	78	0	78
Glycogen phosphorylase, muscle form	0	1	0	1
Renin	0	5	0	5
Carbonic anhydrase 1	0	23	2	40
Carbonic anhydrase 2	0	25	2	42
Carbonic anhydrase 2	0	2	0	2
Cytochrome P450 1A2	0	10	2	12
Carbonic anhydrase 3	0	10	2	18
Cathepsin B	0	1	0	1
Cytochrome P450 3A4	0	19	1	21
Steryl-sulfatase	0	1	0	2
Polyunsaturated fatty acid 5-lipoxygenase	0	3	0	3
Cytochrome P450 2C8	0	3	0	3
Cytochrome P450 2D6	0	13	2	15
Cytochrome P450 2A6	0	4	1	5
Androgen receptor	0	10	0	11
Gamma-aminobutyric acid receptor subunit beta-1	38	3	3	44
Translocator protein	0	3	1	4
Gamma-aminobutyric acid receptor subunit delta	38	3	3	44
Gamma-aminobutyric acid receptor subunit gamma-2	38	3	3	44
Gamma-aminobutyric acid receptor subunit alpha-5	38	3	3	44
Gamma-aminobutyric acid receptor subunit alpha-3	38	3	3	44
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
Cytochrome P450 2B6	0	2	1	3
Carbonic anhydrase 4	0	20	2	30
Carbonic anhydrase 6	0	12	2	22
Gamma-aminobutyric acid receptor subunit gamma-1	38	3	3	44
Gamma-aminobutyric acid receptor subunit alpha-2	38	3	3	44
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Adenosine receptor A1	0	7	1	12
Serum paraoxonase/arylesterase 1	0	1	0	1
Dipeptidyl peptidase 4	0	3	0	4
Gamma-aminobutyric acid receptor subunit alpha-4	38	3	3	44
Gamma-aminobutyric acid receptor subunit gamma-3	38	3	3	44
Endochitinase	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	38	3	3	44
Adenosine receptor A2a	0	9	2	16
Delta-type opioid receptor	0	4	0	4
Cytochrome P450 2C19	0	13	1	15
Delta-type opioid receptor	0	4	0	4
Mu-type opioid receptor	0	6	0	6
Carbonic anhydrase 5A, mitochondrial	0	13	2	24
Carbonic anhydrase	0	10	0	13
Kappa-type opioid receptor	0	2	0	2
Carbonic anhydrase 7	0	11	2	21
Carbonic anhydrase	0	1	0	1
D(1A) dopamine receptor	9	1	0	10
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Carbonic anhydrase	0	1	0	5
D(2) dopamine receptor	0	6	0	7
Gamma-aminobutyric acid receptor subunit alpha-1	38	4	3	45
Gamma-aminobutyric acid receptor subunit beta-3	38	3	3	44
Gamma-aminobutyric acid receptor subunit beta-2	38	3	3	44
Cholinesterase	0	3	0	3
Carbonic anhydrase	0	1	0	1
Mu-type opioid receptor	0	4	1	5
Fatty-acid amide hydrolase 1	0	7	0	9
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	10	3	16
Squalene synthase	0	3	0	3
Neuronal acetylcholine receptor subunit alpha-7	0	3	3	7
Carbonic anhydrase 9	0	12	2	23
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase, alpha family	0	3	0	3
Carbonic anhydrase	0	1	0	5
Carbonic anhydrase 3	0	4	0	4
Carbonic anhydrase	0	2	0	7
Carbonic anhydrase	0	1	0	6
Carbonic anhydrase	0	2	0	2
Sigma intracellular receptor 2	0	1	0	1
Delta carbonic anhydrase	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	2	0	2
Renin	0	2	0	2
Carbonic anhydrase	0	1	0	5
Endochitinase A1	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	1
Carbonic anhydrase 13	0	3	2	8
GABA theta subunit	38	3	3	44
Canalicular multispecific organic anion transporter 1	0	48	0	49
Carbonic anhydrase 4	0	2	0	5
Carbonic anhydrase 15	0	10	0	14
Acidic mammalian chitinase	0	1	0	1
Carbonic anhydrase 13	0	10	0	17
Carbonic anhydrase 7	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	38	3	3	44
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase 14	0	10	2	21
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 2, isoform A	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	11	2	22
Chain A, MTA/SAH nucleosidase	0	1	0	1
Chain A, Ribosome-inactivating protein alpha-trichosanthin	0	0	1	1
Chain A, Ricin A chain	0	0	1	1
Chain A, Ribosome-inactivating protein 3	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
pregnane X nuclear receptor	48	0	0	48
nuclear factor erythroid 2-related factor 2 isoform 2	18	0	0	18
heat shock protein beta-1	21	0	0	21
tumor susceptibility gene 101 protein	1	0	0	1
Voltage-dependent calcium channel gamma-2 subunit	24	0	0	24
Cyclin-dependent kinase 1	0	2	0	2
Heat shock protein HSP 90-beta	0	2	1	4
Glutamate receptor 2	26	4	4	36
Xanthine dehydrogenase/oxidase	0	7	0	7
TAR DNA-binding protein 43	19	0	0	19
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Leucine-rich repeat serine/threonine-protein kinase 2	0	2	0	2
ATPase family AAA domain-containing protein 5	14	0	0	14
Ataxin-2	25	0	0	25
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain B, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, tRNA (guanine-N(1)-)-methyltransferase	0	0	1	1
Chain A, Uncharacterized protein MJ0883	0	0	1	1
signal transducer and activator of transcription 6, interleukin-4 induced	2	0	0	2
NPYLR7B	0	0	3	3
glycogen synthase kinase-3 beta isoform 1	0	0	2	2
nuclear receptor ROR-gamma isoform 1	21	0	0	21
high affinity choline transporter 1 isoform a	0	1	0	1
Sodium/nucleoside cotransporter 1	0	2	0	2
Calcium dependent protein kinase	0	1	0	1
Mitogen-activated protein kinase kinase kinase 7	0	0	3	3
Sodium/nucleoside cotransporter 2	0	2	0	2
Purine nucleoside phosphorylase	0	3	0	3
Epidermal growth factor receptor	0	11	0	11
Phosphoglycerate kinase 1	0	1	0	1
Adenosine deaminase	0	0	0	1
Avidin	0	0	1	1
Adenosine deaminase	0	0	0	1
Glyceraldehyde-3-phosphate dehydrogenase	0	2	0	2
Receptor tyrosine-protein kinase erbB-2	0	4	0	4
Insulin receptor	0	0	0	1
Phosphoglycerate kinase 2	0	1	0	1
Heat shock protein HSP 90-alpha	0	2	2	5
Platelet-derived growth factor receptor beta	0	0	0	1
Adenosine receptor A3	0	18	3	22
Heat shock 70 kDa protein 1A	0	2	1	3
Heat shock cognate 71 kDa protein	0	0	2	2
Fibroblast growth factor receptor 1	0	0	0	1
Inosine-5'-monophosphate dehydrogenase 2	0	1	0	1
Endoplasmin	0	1	1	3
Inosine-5'-monophosphate dehydrogenase 1	0	1	0	1
Fibroblast growth factor receptor 2	0	0	0	1
Fibroblast growth factor receptor 4	0	0	0	1
Fibroblast growth factor receptor 3	0	0	0	1
Streptavidin	0	0	1	1
Adenosylhomocysteinase	0	0	0	1
Adenosine receptor A3	0	3	0	3
Adenosine receptor A2a	0	6	6	14
Adenosine receptor A2b	0	2	1	5
Adenosine receptor A2b	0	3	1	5
Adenylate kinase 2, mitochondrial	0	2	0	3
Adenosine receptor A1	0	6	4	13
Adenylate kinase isoenzyme 1	0	2	0	3
Phosphatidylinositol 4-kinase alpha	0	4	0	5
Adenosine receptor A1	0	1	1	2
Adenosine kinase	0	0	0	1
Adenosine deaminase	0	0	0	1
Equilibrative nucleoside transporter 2	0	2	0	2
Phosphatidylinositol 4-kinase type 2-beta	0	4	0	5
Histone-lysine N-methyltransferase, H3 lysine-79 specific	0	1	0	1
Equilibrative nucleoside transporter 1	0	2	0	2
Phosphatidylinositol 4-kinase type 2-alpha	0	4	0	5
Solute carrier family 28 member 3	0	2	0	2
Adenosine kinase	0	1	0	2
Phosphatidylinositol 4-kinase beta	0	4	0	5
5-methylthioadenosine/S-adenosylhomocysteine deaminase	0	0	0	1
Adenosine transporter 1	0	0	0	1
Chain A, Heat Shock Protein 90	0	0	1	1
Chain A, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain B, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, Myosin Ie Heavy Chain	0	0	1	1
Chain A, Preprotein translocase secA	0	0	1	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Phosphoribosylformylglycinamidine synthase	0	1	0	1
Chain A, nucleoside diphosphate kinase A	0	0	1	1
Chain B, nucleoside diphosphate kinase A	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A, Kinesin-like protein KIF11	0	1	0	1
HPr kinase/phosphorylase	0	0	1	1
ATP-dependent molecular chaperone HSP82	0	0	0	1
2-dehydropantoate 2-reductase	0	2	2	4
Endoplasmic reticulum chaperone BiP	0	0	1	1
Pyruvate kinase PKM	0	0	0	1
Pyruvate kinase PKLR	0	0	0	1
Heat shock cognate 71 kDa protein	0	0	1	1
5'-nucleotidase	0	2	0	2
Mu-type opioid receptor	0	6	2	8
Delta-type opioid receptor	0	4	2	6
Kappa-type opioid receptor	0	4	2	6
Endoplasmin	0	1	1	2
P2Y purinoceptor 2	0	0	2	2
P2X purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	2	2
P2Y purinoceptor 1	0	0	2	2
P2X purinoceptor 1	0	0	1	1
P2X purinoceptor 4	0	0	1	1
P2X purinoceptor 5	0	0	1	1
P2X purinoceptor 6	0	0	1	1
P2X purinoceptor 3	0	0	1	1
Inositol monophosphatase 1	9	0	0	9
Heat shock protein 75 kDa, mitochondrial	0	1	0	1
P2Y purinoceptor 6	0	0	1	1
P2Y purinoceptor 11	0	0	2	2
P2Y purinoceptor 12	0	0	1	1
Sensor protein kinase WalK	0	1	0	1
P2X purinoceptor 2	0	0	1	1
Chain A, Glycogen Phosphorylase B	0	0	1	1
Chain B, Glycogen Phosphorylase B	0	0	1	1
Chain A, ADP-dependent glucokinase	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, phosphodiesterase-nucleotide pyrophosphatase	0	1	0	1
Chain A, GLYCOGEN PHOSPHORYLASE B	0	0	1	1
Chain B, GLYCOGEN PHOSPHORYLASE B	0	0	1	1
Chain A, GLYCOGEN PHOSPHORYLASE B	0	0	1	1
v-jun sarcoma virus 17 oncogene homolog (avian)	26	0	0	26
2'-deoxynucleoside 5'-phosphate N-hydrolase 1	0	1	0	1
2'-deoxynucleoside 5'-phosphate N-hydrolase 1	0	1	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	1	1
Transient receptor potential cation channel subfamily M member 2	0	1	0	1
Alcohol dehydrogenase E chain	0	1	0	1
Alcohol dehydrogenase S chain	0	1	0	1
L-lactate dehydrogenase A chain	0	3	1	4
Adenylate kinase isoenzyme 1	0	0	0	1
Fructose-1,6-bisphosphatase 1	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	2	0	3
Fructose-1,6-bisphosphatase 1	0	1	0	1
Inosine-5'-monophosphate dehydrogenase	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	2	0	2
Amine oxidase [flavin-containing] B	0	3	0	3
5'-nucleotidase	0	0	0	1
GTP:AMP phosphotransferase AK3, mitochondrial	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	2	2
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	1	1
Adenylate kinase 2, mitochondrial	0	0	0	1
Glycine--tRNA ligase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	2	2
Adenosine deaminase-like protein	0	0	0	1
Protease	0	1	1	2
Histamine H3 receptor	0	1	0	2
5'-AMP-activated protein kinase subunit gamma-3	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	1	1
5'-AMP-activated protein kinase subunit beta-1	0	0	2	2
Chain A, HADH2 protein	26	0	0	26
Chain B, HADH2 protein	26	0	0	26
Chain A, 2-oxoglutarate Oxygenase	30	0	0	30
Chain A, ATP-DEPENDENT DNA HELICASE Q1	10	0	0	10
Chain A, Ferritin light chain	17	0	0	17
Luciferase	27	0	0	27
endonuclease IV	13	0	0	13
15-lipoxygenase, partial	14	0	0	14
WRN	1	0	0	1
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
NFKB1 protein, partial	11	0	0	11
GLS protein	34	0	0	34
Thrombopoietin	13	0	0	13
apical membrane antigen 1, AMA1	7	0	0	7
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	11	0	0	11
nonstructural protein 1	9	0	0	9
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	9	0	0	9
peripheral myelin protein 22 isoform 1	14	0	0	14
cellular tumor antigen p53 isoform a	12	0	0	12
polyunsaturated fatty acid lipoxygenase ALOX12	5	0	0	5
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	22	0	0	22
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	10	0	0	10
potassium voltage-gated channel subfamily H member 2 isoform d	19	0	0	19
ras-related protein Rab-9A	12	0	0	12
serine/threonine-protein kinase mTOR isoform 1	13	0	0	13
histone-lysine N-methyltransferase 2A isoform 2 precursor	7	0	0	7
cytochrome P450 3A4 isoform 1	38	0	0	38
M-phase phosphoprotein 8	17	0	0	17
muscarinic acetylcholine receptor M1	22	0	0	22
pyruvate kinase PKM isoform b	2	0	0	2
Polyunsaturated fatty acid lipoxygenase ALOX15B	14	1	0	15
Tyrosine-protein kinase JAK2	0	1	0	1
Ornithine decarboxylase	2	0	0	3
Tyrosine-protein kinase JAK1	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	9	3	15
Tyrosine-protein kinase JAK3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	9	3	15
Glutamate receptor ionotropic, NMDA 2C	0	9	3	15
Tyrosyl-DNA phosphodiesterase 1	0	1	0	1
large T antigen	0	1	0	1
Sex hormone-binding globulin	0	0	4	4
Corticosteroid-binding globulin	0	5	0	5
Mineralocorticoid receptor	0	7	5	13
Mineralocorticoid receptor	0	3	0	3
Solute carrier organic anion transporter family member 1A1	0	2	0	6
Fumarate hydratase	14	0	0	14
polyprotein	14	0	0	14
Pepsin A	0	1	0	1
Renin-1	0	1	0	1
Renin	0	1	0	1
Cathepsin D	0	1	0	1
Renin	0	1	0	1
Protease	0	1	0	1
interleukin 8	12	0	0	12
progesterone receptor	28	0	0	28
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	2
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase	0	1	0	1
Nuclear receptor ROR-gamma	0	1	0	1
Xanthine dehydrogenase/oxidase	0	4	1	7
Purine nucleoside phosphorylase	0	0	1	1
Shiga toxin subunit A	0	2	0	2
Histamine H3 receptor	0	2	0	2
neuropeptide S receptor isoform A	9	0	0	9
Cannabinoid receptor 1	0	7	1	10
Cannabinoid receptor 2	0	6	1	9
Potassium channel subfamily K member 3	0	3	0	3
Cannabinoid receptor 2	0	2	0	2
Cannabinoid receptor 2	0	2	0	2
Chain U, UROKINASE-TYPE PLASMINOGEN ACTIVATOR	0	1	0	1
Chain A, UROKINASE-TYPE PLASMINOGEN ACTIVATOR	0	1	0	1
Chain A, UROKINASE-TYPE PLASMINOGEN ACTIVATOR	0	1	0	1
acetylcholinesterase	22	0	0	22
alpha-galactosidase	5	0	0	5
lysosomal alpha-glucosidase preproprotein	11	0	0	11
huntingtin isoform 2	4	0	0	4
Membrane primary amine oxidase	0	1	0	1
Solute carrier family 22 member 1	0	13	0	17
Prothrombin	0	3	2	5
Coagulation factor X	0	1	0	1
Plasminogen	0	1	0	1
Urokinase-type plasminogen activator	0	3	0	3
Tissue-type plasminogen activator	0	2	0	2
Cationic trypsin	0	2	0	2
Coagulation factor XI	0	1	0	1
Plasma kallikrein	0	1	0	5
Vitamin K-dependent protein C	0	1	0	1
Urokinase-type plasminogen activator	0	2	0	2
Trypsin-1	0	2	0	2
Trypsin-2	0	2	0	2
Sodium/hydrogen exchanger 1	0	1	0	1
Amine oxidase [flavin-containing] A	0	3	0	4
Sodium/hydrogen exchanger 1	0	2	0	2
Sodium/hydrogen exchanger 3	0	2	0	2
Trypsin-3	0	2	0	2
Amiloride-sensitive sodium channel subunit alpha	0	1	0	1
5-hydroxytryptamine receptor 7	0	8	0	8
Sodium/hydrogen exchanger 2	0	2	0	2
Acid-sensing ion channel 1	0	1	0	1
Sodium channel protein type 5 subunit alpha	0	5	0	5
Sodium/hydrogen exchanger 5	0	2	0	2
Solute carrier family 22 member 1	0	7	0	9
Solute carrier family 22 member 2	0	7	0	8
Acid-sensing ion channel 3	0	1	0	1
Sodium/hydrogen exchanger	0	1	0	1
Smad3	14	0	0	14
G	34	0	0	34
NEDD8-activating enzyme E1 regulatory subunit isoform a	0	1	0	1
NEDD8-conjugating enzyme Ubc12	0	1	0	1
histone acetyltransferase KAT2A isoform 1	28	0	0	28
Voltage-dependent L-type calcium channel subunit alpha-1C	0	5	0	5
Interferon beta	41	0	0	41
HLA class I histocompatibility antigen, B alpha chain	34	0	0	34
ATP-dependent translocase ABCB1	0	22	1	29
Alpha-2A adrenergic receptor	0	23	4	30
Alpha-2C adrenergic receptor	0	22	4	29
Alpha-2B adrenergic receptor	0	12	6	18
Voltage-dependent L-type calcium channel subunit alpha-1C	0	7	0	7
Alpha-2C adrenergic receptor	0	11	6	17
Alpha-2A adrenergic receptor	0	12	6	18
Alpha-1D adrenergic receptor	0	26	6	36
Alpha-1A adrenergic receptor	0	11	8	25
Alpha-1B adrenergic receptor	0	10	7	21
5-hydroxytryptamine receptor 6	0	14	1	15
Spike glycoprotein	32	1	2	35
Sodium-dependent dopamine transporter	0	16	0	16
Voltage-dependent L-type calcium channel subunit alpha-1C	0	7	0	8
Potassium channel subfamily K member 2	0	3	0	3
Inositol hexakisphosphate kinase 1	34	0	0	34
cytochrome P450 2C9, partial	34	0	0	34
Fatty-acid amide hydrolase 1	0	7	0	7
Fatty-acid amide hydrolase 1	0	1	0	2
Fatty acid-binding protein, liver	0	2	0	2
Glutamate receptor 1	2	4	4	12
Glutamate receptor 3	2	4	4	12
Glutamate receptor 4	2	4	4	12
Alpha-1A adrenergic receptor	0	28	6	34
Cannabinoid receptor 1	0	1	0	1
Corticotropin-releasing factor receptor 2	0	1	0	1
Lanosterol 14-alpha demethylase	0	4	1	5
Transient receptor potential cation channel subfamily V member 1	0	1	2	4
Transient receptor potential cation channel subfamily V member 2	0	4	1	5
Type-1A angiotensin II receptor	0	9	4	13
Type-1B angiotensin II receptor	0	10	0	10
Type-2 angiotensin II receptor	0	9	0	9
Atrial natriuretic peptide receptor 3	0	2	0	2
Type-1 angiotensin II receptor	0	0	1	1
Type-1 angiotensin II receptor	0	13	5	25
Type-2 angiotensin II receptor	0	7	0	7
Chain A, ADIPOCYTE LIPID-BINDING PROTEIN	0	0	1	1
Chain A, SERUM ALBUMIN	0	0	2	2
Chain A, SERUM ALBUMIN	0	0	2	2
thioredoxin glutathione reductase	10	0	0	10
ubiquitin carboxyl-terminal hydrolase 2 isoform a	9	0	0	9
lethal(3)malignant brain tumor-like protein 1 isoform I	8	0	0	8
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	2	1	0	3
caspase-1 isoform alpha precursor	4	0	0	4
Prostaglandin G/H synthase 1	0	3	0	4
Trypsin	0	2	0	2
Coagulation factor VII	0	3	0	3
60 kDa chaperonin	0	5	0	5
60 kDa heat shock protein, mitochondrial	0	6	0	6
Aromatase	0	6	0	6
Tissue factor	0	3	0	3
Prostaglandin G/H synthase 2	0	9	1	11
Nuclear receptor subfamily 4 group A member 2	0	0	2	2
10 kDa heat shock protein, mitochondrial	0	6	0	6
Calmodulin	0	1	1	3
Disintegrin and metalloproteinase domain-containing protein 17	8	0	0	8
Prostaglandin G/H synthase 2	0	2	0	3
Solute carrier organic anion transporter family member 2A1	0	1	0	3
Thiosulfate sulfurtransferase	0	6	0	6
60 kDa chaperonin	0	6	0	6
10 kDa chaperonin	0	6	0	6
Solute carrier organic anion transporter family member 1B3	0	14	0	19
Cytosolic phospholipase A2 gamma	0	1	0	1
Solute carrier organic anion transporter family member 1B1	0	15	0	21
hypothetical protein, conserved	4	0	0	4
aryl hydrocarbon receptor	33	0	0	33
thyroid stimulating hormone receptor	20	0	0	20
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
Nitric oxide synthase, endothelial	0	2	0	4
Nitric oxide synthase, brain	0	4	0	5
Nitric oxide synthase, brain	0	3	0	5
Nitric oxide synthase, inducible	0	3	0	4
Nitric oxide synthase, inducible	0	3	1	7
Cationic amino acid transporter 3	0	1	0	1
Vasopressin V2 receptor	0	3	1	5
Oxytocin receptor	0	1	1	2
Vasopressin V1a receptor	0	0	3	3
Vasopressin V1a receptor	0	2	2	4
Vasopressin V1b receptor	0	1	1	2
Vasopressin V2 receptor	0	0	1	1
Vasopressin V1b receptor	0	1	1	3
Translocator protein	0	1	0	2
Oxytocin receptor	0	1	1	2
Vasopressin V2 receptor	0	1	1	2
Chain A, Hyaluronidase, phage associated	0	1	0	1
vitamin D (1,25- dihydroxyvitamin D3) receptor	40	0	0	40
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	2	0	2
Urease	0	2	0	2
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	2	0	2
Alpha-2B adrenergic receptor	0	23	3	29
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	1	0	2
Solute carrier family 23 member 1	0	1	0	1
Excitatory amino acid transporter 4	0	2	0	2
Glutamate transporter homolog	0	0	1	1
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	1	0	1
5-hydroxytryptamine receptor 1D	0	2	0	5
Excitatory amino acid transporter 1	0	3	0	4
Excitatory amino acid transporter 2	0	3	0	4
Excitatory amino acid transporter 3	0	3	0	4
Carbonic anhydrase-like protein, putative	0	0	0	5
Glutamate receptor ionotropic, NMDA 2D	0	8	3	14
Glutamate receptor ionotropic, NMDA 3B	0	8	3	14
Glutamate receptor ionotropic, NMDA 3A	0	8	3	14
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
EWS/FLI fusion protein	26	0	0	26
peroxisome proliferator-activated receptor delta	31	0	0	31
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
Prostaglandin-H2 D-isomerase	0	1	0	1
Prostaglandin G/H synthase 2	0	2	0	2
Fatty acid-binding protein, liver	0	4	0	4
Integrin beta-3	8	1	1	10
Myeloperoxidase	0	4	0	4
Prostaglandin G/H synthase 1	0	3	0	3
Seed linoleate 13S-lipoxygenase-1	0	3	0	5
Integrin alpha-IIb	8	1	1	10
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	4	0	4
Substance-P receptor	0	3	0	3
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Nuclear receptor ROR-gamma	17	1	1	19
Ras-related protein Rab-2A	0	0	1	1
Rho-associated protein kinase 2	0	1	0	1
Nicotinate phosphoribosyltransferase	0	2	0	2
Solute carrier family 22 member 20	0	2	0	2
Solute carrier family 22 member 6	0	2	0	3
Sigma non-opioid intracellular receptor 1	0	14	1	15
Sigma non-opioid intracellular receptor 1	0	0	1	1
Beta-1 adrenergic receptor	0	1	5	8
D(1A) dopamine receptor	17	0	0	17
Beta-2 adrenergic receptor	0	19	8	28
Beta-1 adrenergic receptor	0	16	7	23
Beta-3 adrenergic receptor	0	7	7	14
Beta-2 adrenergic receptor	0	1	6	9
SMAD family member 2	15	0	0	15
SMAD family member 3	15	0	0	15
caspase 7, apoptosis-related cysteine protease	8	0	0	8
peroxisome proliferator activated receptor gamma	42	0	0	42
caspase-3	8	0	0	8
Caspase-7	7	0	0	7
caspase-3	7	0	0	7
Solute carrier organic anion transporter family member 2B1	0	2	0	3
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	2	0	2
Insulin receptor	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	11	2	14
Atrial natriuretic peptide receptor 1	0	1	1	2
Atrial natriuretic peptide receptor 1	0	0	1	1
cystic fibrosis transmembrane conductance regulator	0	1	0	2
DNA polymerase beta	9	0	0	9
short transient receptor potential channel 6 isoform 1	0	0	2	2
5-hydroxytryptamine receptor 4	0	20	0	20
Muscarinic acetylcholine receptor M2	0	8	3	16
Muscarinic acetylcholine receptor M4	0	8	1	12
Muscarinic acetylcholine receptor M1	0	6	1	9
Muscarinic acetylcholine receptor M3	0	5	1	8
Muscarinic acetylcholine receptor M4	0	5	1	8
Muscarinic acetylcholine receptor M5	0	4	1	7
Muscarinic acetylcholine receptor M5	0	8	1	12
Muscarinic acetylcholine receptor M2	0	5	1	9
Muscarinic acetylcholine receptor M1	0	8	2	15
Muscarinic acetylcholine receptor M1	0	0	0	1
Muscarinic acetylcholine receptor M3	0	9	2	14
5-hydroxytryptamine receptor 2C	0	21	1	22
Muscarinic acetylcholine receptor M4	0	2	0	2
Reverse transcriptase/RNaseH	0	0	0	1
Muscarinic acetylcholine receptor	0	2	2	4
Neuronal acetylcholine receptor subunit alpha-4	4	2	3	10
Neuronal acetylcholine receptor subunit beta-2	4	2	3	10
Thromboxane A2 receptor	0	2	1	7
Endothelin-1 receptor	0	3	1	4
Sodium/bile acid cotransporter	0	4	0	4
Multidrug and toxin extrusion protein 1	0	11	0	11
Leukotriene B4 receptor 2	0	0	3	4
hypoxia-inducible factor 1 alpha subunit	16	0	0	16
farnesoid X nuclear receptor	32	0	0	32
activating transcription factor 6	25	0	0	25
Proton-coupled amino acid transporter 1	0	4	0	4
Angiotensin-converting enzyme	0	13	1	15
Angiotensin-converting enzyme	0	20	0	21
Liver carboxylesterase 1	0	0	0	2
Angiotensin-converting enzyme	0	5	0	5
glp-1 receptor, partial	16	0	0	16
calpain II, partial	0	1	0	1
Skn7p	0	0	0	1
envelope glycoprotein	0	1	0	1
photoreceptor-specific nuclear receptor	0	1	0	1
perilipin-5	0	2	0	2
nuclear receptor corepressor 2 isoform 2	0	1	0	1
perilipin-1	0	2	0	2
peroxisome proliferator-activated receptor gamma isoform 2	0	1	0	1
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	2	0	2
replicative DNA helicase	0	0	0	1
recombinase A	0	0	1	1
streptokinase A precursor	0	0	1	1
Eyes absent homolog 2	0	1	0	1
Polymerase acidic protein	0	0	1	1
Estrogen receptor	0	0	1	1
Alpha-1B adrenergic receptor	0	26	5	31
Tyrosine-protein phosphatase non-receptor type 1	0	4	0	4
Mitogen-activated protein kinase 1	0	2	0	2
Multidrug resistance-associated protein 1	0	3	0	5
Alpha-synuclein	4	4	0	8
5-hydroxytryptamine receptor 2B	0	26	1	27
Cytochrome P450 2J2	0	12	0	12
Monocarboxylate transporter 1	0	2	0	2
Eyes absent homolog 3	0	1	0	1
Aldo-keto reductase family 1 member C1	0	1	0	1
Solute carrier family 22 member 6	0	3	0	6
Estrogen receptor beta	0	0	1	1
Monocarboxylate transporter 2	0	2	0	2
Rap guanine nucleotide exchange factor 4	4	0	0	4
Bile acid receptor	0	2	1	3
Solute carrier family 22 member 12	0	1	0	1
Eyes absent homolog 3	0	1	0	1
Inosine-5'-monophosphate dehydrogenase	0	1	0	1
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	1
M17 leucyl aminopeptidase	0	1	0	1
M1-family alanyl aminopeptidase	0	1	0	1
Caspase-7	3	0	0	3
ATAD5 protein, partial	27	0	0	27
Beta-1 adrenergic receptor	0	4	1	5
B2 bradykinin receptor	0	1	0	1
B2 bradykinin receptor	0	2	1	5
B1 bradykinin receptor	0	1	0	1
Olfactory receptor 51E2	0	0	2	2
Sodium/glucose cotransporter 1	0	1	1	2
Sodium/glucose cotransporter 2	0	1	1	2
Aldo-keto reductase family 1 member B1	0	18	0	18
Sodium-dependent noradrenaline transporter	0	16	0	16
Thromboxane-A synthase	0	4	0	4
Type-1 angiotensin II receptor	0	5	1	6
thyrotropin-releasing hormone receptor	4	0	0	4
hemoglobin subunit beta	2	0	0	2
Cruzipain	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	1	5	6
NEDD8-activating enzyme E1 regulatory subunit	0	1	1	2
NEDD8-activating enzyme E1 catalytic subunit	0	0	1	1
DNA polymerase kappa	0	1	0	1
DNA polymerase iota	0	1	0	1
DNA polymerase eta	0	1	0	1
PPM1D protein	4	0	0	4
Acetylcholinesterase	0	2	0	2
Cytochrome P450 1A1	0	6	1	7
Cytochrome P450 2C11	0	2	0	2
5-hydroxytryptamine receptor 1A	0	4	2	6
Steroid 17-alpha-hydroxylase/17,20 lyase	0	1	0	1
Cytochrome P450 3A5	0	1	0	1
D(1A) dopamine receptor	0	14	1	17
Cytochrome P450 3A7	0	1	0	1
Caspase-1	0	1	1	2
N-acylethanolamine-hydrolyzing acid amidase	0	1	0	1
Heat sensitive channel TRPV3	0	1	1	2
Sigma intracellular receptor 2	0	2	0	2
Transient receptor potential cation channel subfamily A member 1	0	1	2	3
Transient receptor potential cation channel subfamily M member 8	0	1	1	2
Transient receptor potential cation channel subfamily V member 4	0	1	1	2
G-protein coupled receptor 55	0	0	1	1
Diacylglycerol lipase-alpha	0	2	0	2
Histamine H3 receptor	0	4	2	6
Vpr	2	0	0	2
Chain A, angiotensin converting enzyme	0	1	0	1
Chain A, angiotensin converting enzyme	0	1	0	1
Metallo-beta-lactamase type 2	0	1	1	2
transient receptor potential cation channel subfamily V member 1	1	0	0	1
Neprilysin	0	1	0	1
Neprilysin	0	2	0	2
Leukotriene A-4 hydrolase	0	3	1	4
EEF1AKMT4-ECE2 readthrough transcript protein	0	1	0	1
Leukotriene A-4 hydrolase	0	1	0	1
Thymidine phosphorylase	0	0	1	2
Endothelin-converting enzyme 1	0	1	0	1
Succinyl-diaminopimelate desuccinylase	0	3	0	3
Solute carrier family 15 member 1	0	2	0	2
Beta-lactamase TEM	0	1	0	1
Beta-lactamase	0	2	0	3
Beta-lactamase	0	2	0	2
Angiotensin-converting enzyme 2	0	5	2	7
Beta-lactamase class B VIM-2	0	1	1	2
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 16	0	0	0	1
Solute carrier family 22 member 21	0	0	0	1
Solute carrier family 22 member 5	0	0	0	1
Toll-like receptor 4	0	1	0	1
Solute carrier family 22 member 2	0	5	0	7
Amyloid-beta precursor protein	0	7	0	7
D(2) dopamine receptor	0	15	2	18
UDP-glucuronosyltransferase 1A1	0	3	0	4
5-hydroxytryptamine receptor 2A	0	16	1	17
D(3) dopamine receptor	0	19	0	20
Potassium channel subfamily K member 10	0	1	0	1
Nuclear receptor subfamily 3 group C member 3	0	12	0	12
Chain A, Neutrophil gelatinase-associated lipocalin	0	0	1	1
Nrf2	2	0	0	2
Parkin	8	0	0	8
NPC intracellular cholesterol transporter 1 precursor	5	0	0	5
Tyrosine-protein kinase Fyn	0	5	0	5
3-dehydroquinate synthase	0	1	0	2
Polyunsaturated fatty acid lipoxygenase ALOX15	0	10	0	10
Matrix metalloproteinase-9	0	3	0	3
Prolyl 4-hydroxylase subunit alpha-1	0	2	0	2
Potassium-transporting ATPase subunit beta	0	1	0	2
Potassium-transporting ATPase alpha chain 1	0	1	0	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	1	0	1
Autoinducer 2-binding periplasmic protein LuxP	0	1	0	1
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	3	0	3
Arginase-1	0	1	0	1
phosphoglycerate kinase	3	0	0	3
ORF73	0	0	1	1
Proteasome subunit beta type-11	0	0	0	1
NADPH oxidase 1	0	1	0	1
67.9K protein	10	0	0	10
Snq2p	0	0	0	1
Adenylate cyclase type 1	0	2	0	2
Spike glycoprotein	0	1	2	3
Replicase polyprotein 1ab	0	1	2	3
histone deacetylase 9 isoform 3	4	0	0	4
atrial natriuretic peptide receptor 2 precursor	4	0	0	4
Proteasome subunit alpha type-7	0	0	0	1
Transmembrane protease serine 2	0	1	2	3
Glutamate receptor ionotropic, NMDA 2D	0	3	0	3
Transient receptor potential cation channel subfamily V member 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1F	0	3	0	3
Bile salt export pump	0	9	0	9
Albumin	0	1	3	5
Albumin	0	0	1	1
Major prion protein	0	0	1	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	2	0	2
Major prion protein	0	0	1	1
Procathepsin L	0	1	2	3
Replicase polyprotein 1a	0	1	2	3
Replicase polyprotein 1ab	0	1	2	3
Replicase polyprotein 1ab	0	4	2	6
Cys-loop ligand-gated ion channel	0	1	0	1
Calmodulin-1	0	3	1	4
Replicase polyprotein 1ab	0	5	2	7
Sphingomyelin phosphodiesterase	0	1	0	1
D	0	4	0	4
D(3) dopamine receptor	0	5	0	5
D(2) dopamine receptor	0	1	0	1
Proteasome subunit beta type-1	0	1	0	2
Substance-K receptor	0	2	0	2
D(4) dopamine receptor	0	6	1	8
D(1B) dopamine receptor	0	1	0	2
Adenylate cyclase type 3	0	2	0	2
UDP-glucuronosyltransferase 1A4	0	1	0	2
Alpha-1D adrenergic receptor	0	14	5	20
Sodium-dependent dopamine transporter	0	4	0	4
Histamine H2 receptor	0	5	2	7
D(1B) dopamine receptor	0	3	0	3
Proteasome subunit alpha type-1	0	0	0	1
Proteasome subunit alpha type-2	0	0	0	1
Proteasome subunit alpha type-3	0	0	0	1
Proteasome subunit alpha type-4	0	0	0	1
Adenylate cyclase type 2	0	2	0	2
Adenylate cyclase type 4	0	2	0	2
Proteasome subunit beta type-8	0	0	0	1
Proteasome subunit beta type-9	0	0	0	1
Proteasome subunit alpha type-5	0	0	0	1
Proteasome subunit beta type-4	0	0	0	1
Proteasome subunit beta type-6	0	0	0	1
Proteasome subunit beta type-5	0	2	0	3
Trypanothione reductase	0	2	0	2
D(4) dopamine receptor	0	3	0	3
Histamine H1 receptor	0	2	3	5
Melanocortin receptor 4	0	2	0	2
Melanocortin receptor 5	0	2	0	2
Pleiotropic ABC efflux transporter of multiple drugs	0	1	0	2
5-hydroxytryptamine receptor 7	0	2	1	3
Histamine H1 receptor	0	7	2	9
Sodium channel protein type 1 subunit alpha	0	2	0	2
Sodium channel protein type 4 subunit alpha	0	4	0	4
Adenylate cyclase type 8	0	2	0	2
Proteasome subunit beta type-10	0	0	0	1
Melanocortin receptor 3	0	2	0	2
Proteasome subunit beta type-3	0	0	0	1
Proteasome subunit beta type-2	0	1	0	2
Gastrin/cholecystokinin type B receptor	0	1	0	1
Proteasome subunit alpha type-6	0	0	1	2
Aldehyde oxidase 1	0	1	0	1
Sodium channel protein type 7 subunit alpha	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	3	0	3
Adenylate cyclase type 6	0	2	0	2
Adenylate cyclase type 5	0	2	0	2
Glutamate receptor ionotropic, NMDA 1	0	4	0	4
Aldehyde oxidase	0	2	0	2
Glutamate receptor ionotropic, NMDA 2A	0	4	0	4
Glutamate receptor ionotropic, NMDA 2B	0	4	0	4
Voltage-dependent L-type calcium channel subunit alpha-1S	0	3	0	3
Glutamate receptor ionotropic, NMDA 2C	0	3	0	3
Sodium channel protein type 9 subunit alpha	0	3	0	3
Adenylyl cyclase 7	0	2	0	2
Proteasome subunit alpha-type 8	0	0	0	1
Glutamate receptor ionotropic, NMDA 3A	0	3	0	3
D	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	2	0	2
Proteasome subunit beta type-7	0	0	0	1
Sodium channel protein type 3 subunit alpha	0	3	0	3
Sodium channel protein type 11 subunit alpha	0	2	0	2
Sodium channel protein type 8 subunit alpha	0	2	0	2
Sodium channel protein type 10 subunit alpha	0	2	0	2
cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 7	0	0	0	1
Vitamin D3 receptor	0	1	1	4
Glycine receptor subunit alpha-1	0	0	2	2
Vitamin D3 receptor	0	0	1	1
PAX8	0	0	0	1
pregnane X receptor	9	0	0	9
nuclear receptor subfamily 1, group I, member 2	8	0	0	8
nuclear receptor subfamily 0 group B member 1	0	1	0	1
steroidogenic factor 1	0	1	0	1
Solute carrier family 22 member 3	0	5	0	6
Tubulin alpha-1A chain	0	2	1	3
Tubulin beta chain	0	2	1	3
Tubulin beta-4A chain	0	2	2	5
ATP-dependent translocase ABCB1	0	6	0	6
Tubulin beta chain	0	2	2	5
Tubulin alpha-3C chain	0	2	2	5
Serine/threonine-protein kinase pim-1	0	2	1	3
ATP-dependent translocase ABCB1	0	6	0	6
Tubulin alpha-1B chain	0	2	2	5
Tubulin alpha-4A chain	0	2	2	5
Tubulin beta-4B chain	0	2	2	5
Vesicular acetylcholine transporter	0	1	0	1
Tubulin beta-3 chain	0	2	2	5
Tubulin beta-2A chain	0	2	2	5
Tubulin polymerization-promoting protein	0	0	1	1
Tubulin beta-8 chain	0	2	2	5
Tubulin beta-2B chain	0	2	0	2
Tubulin alpha-3E chain	0	2	2	5
Tubulin alpha-1A chain	0	2	2	5
Similar to alpha-tubulin isoform 1	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
CREB-binding protein	1	0	0	1
Tubulin alpha-1C chain	0	2	2	5
Tubulin beta-6 chain	0	2	2	5
Tubulin beta-2B chain	0	2	2	5
Tubulin beta-1 chain	0	2	2	5
Solute carrier family 22 member 3	0	2	0	2
C-8 sterol isomerase	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	1	0	1
dopamine D1 receptor	4	0	0	4
atrial natriuretic peptide receptor 1 precursor	5	0	0	5
Glucocorticoid receptor	0	8	3	16
Glycine receptor subunit alpha-1	0	6	0	6
Glycine receptor subunit beta	0	6	0	6
Glycine receptor subunit alpha-2	0	6	0	6
Glycine receptor subunit alpha-3	0	6	0	6
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Phosphodiesterase	0	3	0	3
Multidrug resistance-associated protein 5	0	0	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	4	0	4
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	5	0	5
Glutathione S-transferase P	0	1	0	1
Alpha-tocopherol transfer protein	0	0	1	1
Solute carrier organic anion transporter family member 1A4	0	1	0	4
Solute carrier organic anion transporter family member 1A5	0	0	0	3
Solute carrier organic anion transporter family member 1A2	0	1	0	4
Solute carrier organic anion transporter family member 1A3	0	1	0	3
G-protein coupled bile acid receptor 1	0	0	1	1
ATP-binding cassette sub-family C member 11	0	0	0	1
Solute carrier family 22 member 11	0	0	0	2
Solute carrier organic anion transporter family member 1A1	0	0	0	1
Solute carrier organic anion transporter family member 1B2	0	0	0	1
Thymidine kinase, cytosolic	0	3	0	6
Deoxycytidine kinase	0	0	0	1
AAA family ATPase	0	0	0	1
Sterol O-acyltransferase 1	0	2	0	2
Alpha-1B adrenergic receptor	0	0	1	1
Alpha-1A adrenergic receptor	0	5	1	6
Nicotinamide phosphoribosyltransferase	0	0	1	1
ATP-binding cassette sub-family C member 8	0	1	1	2
ATP-sensitive inward rectifier potassium channel 11	0	1	1	2
ADP-ribose glycohydrolase MACROD2	0	1	0	1
Aspartate aminotransferase, cytoplasmic	0	2	0	2
runt-related transcription factor 1 isoform AML1b	1	0	0	1
core-binding factor subunit beta isoform 2	1	0	0	1
Prostaglandin E2 receptor EP1 subtype	0	1	1	2
Prostaglandin E2 receptor EP4 subtype	0	1	0	1
Prostaglandin F2-alpha receptor	0	2	0	2
Prostaglandin F2-alpha receptor	0	2	1	3
Prostaglandin E2 receptor EP3 subtype	0	1	1	2
Prostaglandin E2 receptor EP2 subtype	0	1	0	1
Prostaglandin F2-alpha receptor	0	0	1	1
Prostacyclin receptor	0	1	0	1
Prostaglandin D2 receptor	0	1	0	1
Solute carrier family 22 member 7	0	0	0	1
Solute carrier family 22 member 8	0	3	0	5
Solute carrier organic anion transporter family member 2A1	0	1	0	2
Solute carrier organic anion transporter family member 2A1	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	1	0	1
Solute carrier family 22 member 7	0	0	0	1
mu-type opioid receptor isoform MOR-1	0	0	1	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Tyrosine-protein kinase Lck	0	3	1	4
POU domain, class 2, transcription factor 1	0	0	0	1
Alpha-1A adrenergic receptor	0	3	3	6
Interstitial collagenase	0	3	1	4
Solute carrier family 15 member 1	0	2	0	2
Estrogen receptor	0	5	2	7
Progesterone receptor	0	6	2	9
Androgen receptor	0	5	2	7
Voltage-dependent L-type calcium channel subunit alpha-1D	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1S	0	3	0	3
Estrogen receptor beta	0	4	2	6
Adenylate cyclase	0	1	0	1
5-hydroxytryptamine receptor 1B	0	4	1	5
5-hydroxytryptamine receptor 5A	0	1	0	1
UDP-glucuronosyltransferase 2B7	0	1	0	3
UDP-glucuronosyltransferase 1A3	0	0	0	1
NPC1-like intracellular cholesterol transporter 1	0	1	0	1
NPC1-like intracellular cholesterol transporter 1	0	1	0	1
Cathepsin B	0	1	0	1
procathepsin L isoform 1 preproprotein	0	1	0	1
fructose-bisphosphate aldolase	0	1	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	4	4
Aurora kinase B	0	1	1	2
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Chain A, BCL-2-RELATED PROTEIN A1	0	0	2	2
unnamed protein product	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	0	0	1
bcl-2-like protein 11 isoform 1	0	0	2	2
Chymotrypsinogen A	0	4	0	4
Steroid 17-alpha-hydroxylase/17,20 lyase	0	2	0	2
Heme oxygenase 1	0	1	0	1
Lanosterol 14-alpha demethylase	0	1	1	2
Cytochrome P450 11B1, mitochondrial	0	2	0	2
Cytochrome P450 11B2, mitochondrial	0	2	0	2
Heme oxygenase 2	0	1	0	1
Malate dehydrogenase, cytoplasmic	0	2	0	2
Cytochrome P450 144	0	0	2	2
Steroid C26-monooxygenase	0	0	2	2
Steroid C26-monooxygenase	0	0	2	2
Mycocyclosin synthase	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
Sterol 14-alpha demethylase	0	0	1	1
Sterol 14-alpha demethylase	0	1	1	2
14-alpha sterol demethylase	0	0	1	1
heat shock protein 90, putative	0	0	0	1
likely tRNA 2'-phosphotransferase	0	1	0	1
Chain A, Dihydrofolate reductase	0	0	1	1
Thymidylate synthase	0	2	0	2
Thymidylate synthase	0	1	0	2
Dihydrofolate reductase	0	0	1	1
Aldo-keto reductase family 1 member B1	0	3	0	3
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Multidrug resistance associated protein	0	0	0	1
Advanced glycosylation end product-specific receptor	0	1	0	1
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
beta-2 adrenergic receptor	3	0	0	3
Glutathione reductase, mitochondrial	0	5	0	5
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
ATP-citrate synthase	0	1	0	1
Glutamate receptor ionotropic, kainate 1	0	4	2	6
Metabotropic glutamate receptor 3	0	0	1	1
Glutamate receptor ionotropic, kainate 1	0	3	2	5
Metabotropic glutamate receptor 5	0	1	2	4
Glutamate receptor ionotropic, kainate 2	0	4	3	7
Glutamate receptor 1	0	3	2	5
Glutamate receptor 2	0	3	2	5
Glutamate receptor 3	0	1	2	3
Glutamate receptor ionotropic, kainate 3	0	4	0	4
Metabotropic glutamate receptor 8	0	0	1	1
Glutamate receptor 4	0	3	1	4
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Glutamate receptor ionotropic, kainate 4	0	4	0	4
Glutamate carboxypeptidase 2	0	1	0	1
Glutamate receptor ionotropic, kainate 2	0	3	2	5
Glutamate receptor ionotropic, kainate 3	0	3	0	3
Metabotropic glutamate receptor 3	0	1	1	3
Glutamate receptor ionotropic, kainate 5	0	3	0	3
Glutamate receptor ionotropic, kainate 5	0	4	0	4
Glutamate racemase	0	0	0	1
Prolyl 4-hydroxylase	0	1	0	1
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
Ricin	0	1	0	1
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	0	0	1	1
Purine nucleoside phosphorylase	0	0	1	2
Guanine deaminase	0	1	0	2
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Protein (female-specific Histamine Binding Protein 2)	0	0	1	1
aryl hydrocarbon receptor nuclear translocator	0	0	0	1
transforming acidic coiled-coil-containing protein 3	0	0	0	1
Macrophage migration inhibitory factor	0	2	0	2
Histamine H1 receptor	0	2	1	3
Histamine H3 receptor	0	1	0	1
Histamine N-methyltransferase	0	1	0	1
Equilibrative nucleoside transporter 4	0	0	0	1
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	0	1
Histamine H4 receptor	0	1	2	3
Carboxylic ester hydrolase	0	0	0	1
Chain A, HISTIDINE-BINDING PROTEIN	0	0	1	1
Histidine-binding periplasmic protein	0	0	1	1
Large neutral amino acids transporter small subunit 1	0	5	0	5
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	4	0	6
pyruvate kinase	2	0	0	2
N-glycosylase/DNA lyase	0	1	0	1
Lactoperoxidase	0	2	0	2
Single-stranded DNA cytosine deaminase	1	0	0	1
Hsf1 protein	0	0	2	2
Chain B, Pulmonary surfactant-associated protein D	0	1	0	1
Chain A, Pulmonary surfactant-associated protein D	0	1	0	1
Sodium/myo-inositol cotransporter 2	0	1	0	1
Peptidylglycine alpha-amidating monooxygenase	0	0	0	2
hexokinase-4 isoform 1	1	0	0	1
glucokinase regulatory protein	1	0	0	1
Beta-2 adrenergic receptor	0	4	1	6
Beta-1 adrenergic receptor	0	5	3	10
Beta-2 adrenergic receptor	0	0	1	1
Beta-adrenergic receptor kinase 1	0	0	1	1
Beta-3 adrenergic receptor	0	0	1	1
Beta-3 adrenergic receptor	0	3	1	4
Beta-2 adrenergic receptor	0	2	0	2
Taste receptor type 2 member 38	0	0	1	1
Taste receptor type 2 member 39	0	0	1	1
Taste receptor type 2 member 40	0	0	1	1
Taste receptor type 2 member 41	0	0	1	1
Taste receptor type 2 member 43	0	0	1	1
Taste receptor type 2 member 31	0	0	1	1
Taste receptor type 2 member 45	0	0	1	1
Taste receptor type 2 member 46	0	0	1	1
Taste receptor type 2 member 30	0	0	1	1
Taste receptor type 2 member 19	0	0	1	1
Taste receptor type 2 member 20	0	0	1	1
Taste receptor type 2 member 50	0	0	1	1
Taste receptor type 2 member 60	0	0	1	1
Beta-2 adrenergic receptor	0	1	1	2
Taste receptor type 2 member 42	0	0	1	1
Taste receptor type 2 member 16	0	0	1	1
Taste receptor type 2 member 14	0	0	1	2
Taste receptor type 2 member 13	0	0	1	1
Taste receptor type 2 member 10	0	0	1	1
Taste receptor type 2 member 9	0	0	1	1
Taste receptor type 2 member 8	0	0	1	1
Taste receptor type 2 member 7	0	0	1	1
Taste receptor type 2 member 5	0	0	1	1
Taste receptor type 2 member 4	0	0	1	1
Taste receptor type 2 member 3	0	0	1	1
Taste receptor type 2 member 1	0	0	1	1
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	2	0	0	2
Chain A, Glutamate receptor 2	0	0	1	1
Chain A, Glutamate receptor 2	0	0	1	1
Chain C, Glutamate receptor 2	0	0	1	1
Glutamate receptor ionotropic, kainate 4	0	1	0	1
Heparanase	0	0	1	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily A member 5	0	2	0	2
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	4	0	4
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	4	0	4
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	3	0	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	4	0	4
Platelet glycoprotein VI	0	1	3	5
Type-1 angiotensin II receptor	0	2	1	3
5-hydroxytryptamine receptor 1A	0	2	0	2
heat shock 70kDa protein 1A	0	1	0	1
glyceraldehyde-3-phosphate dehydrogenase isoform 1	0	1	0	1
heat shock cognate 71 kDa protein isoform 1	0	1	0	1
dual specificity protein phosphatase 6	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
heat shock cognate 71 kDa protein isoform 2	0	1	0	1
Glutathione S-transferase Mu 1	0	1	0	1
Acetylcholine receptor subunit alpha	0	2	2	4
Neuronal acetylcholine receptor subunit alpha-3	0	2	3	6
Acetylcholine receptor subunit gamma	0	2	2	4
Acetylcholine receptor subunit beta	0	2	2	4
Neuronal acetylcholine receptor subunit alpha-2	0	2	3	6
Neuronal acetylcholine receptor subunit beta-3	0	2	3	6
Neuronal acetylcholine receptor subunit beta-4	0	2	3	6
Neuronal acetylcholine receptor subunit beta-2	0	3	1	5
Neuronal acetylcholine receptor subunit alpha-5	0	2	3	6
Neuronal acetylcholine receptor subunit beta-4	0	3	1	5
Neuronal acetylcholine receptor subunit alpha-3	0	3	1	4
Neuronal acetylcholine receptor subunit alpha-7	0	3	2	5
Neuronal acetylcholine receptor subunit alpha-6	0	2	3	6
Neuronal acetylcholine receptor subunit alpha-9	0	2	3	6
Neuronal acetylcholine receptor subunit alpha-4	0	3	1	5
Acetylcholine receptor subunit epsilon	0	0	2	2
Acetylcholine receptor subunit delta	0	2	2	4
Neuronal acetylcholine receptor subunit alpha-2	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-10	0	2	3	6
ClpP	4	0	0	4
Cytochrome P450 1A2	0	1	0	1
Cholinesterase	0	3	0	3
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	3	0	3
Acetylcholinesterase	0	5	0	5
Acetylcholinesterase	0	1	0	1
Nociceptin receptor	0	1	0	1
Melatonin receptor type 1A	0	2	1	3
Melatonin receptor type 1C	0	0	1	1
Melatonin receptor type 1A	0	1	1	2
Melatonin receptor type 1B	0	2	1	3
Melatonin receptor type 1C	0	1	1	2
Melatonin receptor type 1B	0	1	1	2
Nuclear factor erythroid 2-related factor 2	0	0	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	1	1	2
Carboxylic ester hydrolase	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	3	3
Secreted chorismate mutase	0	2	0	2
Transient receptor potential cation channel subfamily M member 8	0	1	2	4
Transient receptor potential cation channel subfamily A member 1	0	0	4	4
Dihydrofolate reductase	0	1	0	1
galanin receptor type 3	0	1	0	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Aminopeptidase	0	1	0	1
Chain A, Methionine aminopeptidase	0	1	0	1
S-ribosylhomocysteine lyase	0	1	0	1
Adenylate cyclase type 5	0	0	0	1
S-adenosylmethionine synthase isoform type-1	0	0	0	1
S-adenosylmethionine synthase isoform type-2	0	0	0	1
Fatty acid synthase	0	5	0	5
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	1
estrogen receptor beta isoform 1	0	2	0	2
Cystathionine gamma-lyase	0	1	0	1
Carboxypeptidase A1	0	1	0	1
Nuclear receptor corepressor 1	0	1	0	1
Integrin beta-1	0	1	0	1
Integrin alpha-4	0	1	0	1
Nuclear receptor corepressor 2	0	1	0	1
Nischarin	0	1	0	1
Nischarin	0	2	0	2
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	0	0	2
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	0	0	1
Neutrophil elastase	0	4	0	4
Nitric oxide synthase, endothelial	0	3	0	3
Collagenase 3	0	3	0	3
Cholesteryl ester transfer protein	0	1	0	1
D-amino-acid oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 3	0	0	1	1
Nicotinamidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	0	1	1
Hydroxycarboxylic acid receptor 2	0	2	1	3
D-aspartate oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	1	1	2
Equilibrative nucleoside transporter 1	0	1	0	1
B2 bradykinin receptor	0	2	0	2
Quinolone resistance protein NorA	0	2	0	3
5-hydroxytryptamine receptor 3E	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
5-hydroxytryptamine receptor 3B	0	1	0	1
Acetylcholine receptor subunit alpha	0	2	1	3
Acetylcholine receptor subunit beta	0	2	1	3
Acetylcholine receptor subunit gamma	0	2	1	3
Acetylcholine receptor subunit delta	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-4	0	1	0	1
Cytochrome P450 2A5	0	1	0	1
Acetylcholine receptor subunit beta-like 2	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-5	0	0	1	1
5-hydroxytryptamine receptor 3A	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-7	0	2	0	2
Acetylcholine-binding protein	0	1	1	2
Neuronal acetylcholine receptor subunit beta-3	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-6	0	1	1	2
Cytochrome P450 2A13	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-5	0	2	0	2
Liver carboxylesterase B-1	0	1	0	1
5-hydroxytryptamine receptor 3D	0	1	0	1
Neuronal acetylcholine receptor subunit beta-3	0	2	0	2
Neuronal acetylcholine receptor subunit beta-4	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-3	0	2	0	2
Soluble acetylcholine receptor	0	1	0	1
5-hydroxytryptamine receptor 3C	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-2	0	2	0	2
Neuronal acetylcholine receptor subunit beta-2	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-6	0	2	0	2
Integrin beta	0	0	1	1
Glycoprotein IIb	0	0	1	1
Transporter	0	1	1	3
tumor necrosis factor	1	0	0	1
eyes absent homolog 2 isoform a	2	0	0	2
Phospholipase A2, membrane associated	0	0	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	1	0	1
Platelet-activating factor receptor	0	0	0	1
Indoleamine 2,3-dioxygenase 1	0	2	0	2
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	1	0	1
C-C chemokine receptor type 2	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
C-terminal-binding protein 1	1	0	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	2	0	2
Leukotriene B4 receptor 1	0	0	0	1
Myosin light chain kinase, smooth muscle	0	1	0	1
Indoleamine 2,3-dioxygenase 2	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Sodium/iodide cotransporter	0	1	0	1
Chain A, Adipocyte Lipid-binding Protein	0	0	1	1
Chain A, MUSCLE FATTY ACID BINDING PROTEIN	0	0	1	1
Chain A, MUSCLE FATTY ACID BINDING PROTEIN	0	0	1	1
Chain A, MUSCLE FATTY ACID BINDING PROTEIN	0	0	1	1
putative potassium channel subunit	0	0	1	1
serine-protein kinase ATM isoform a	1	0	0	1
Sterol O-acyltransferase 1	0	1	0	1
Fatty acid-binding protein, liver	0	0	1	1
DNA topoisomerase 1	0	2	0	2
Protein kinase C alpha type	0	0	0	1
Sterol O-acyltransferase 1	0	1	0	1
Peroxisome proliferator-activated receptor delta	0	1	1	3
Peroxisome proliferator-activated receptor alpha	1	1	2	4
Proteinase-activated receptor 1	0	1	0	1
Nitric oxide synthase, brain	0	1	0	1
Mcl-1	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	3	0	3
Sodium/potassium-transporting ATPase subunit alpha-1	0	3	0	4
Sodium/potassium-transporting ATPase subunit beta-1	0	3	0	4
Sodium/potassium-transporting ATPase subunit alpha-3	0	2	0	3
Sodium/potassium-transporting ATPase subunit beta-2	0	2	0	3
Bifunctional cytochrome P450/NADPH--P450 reductase	0	0	1	1
UDP-glucuronosyltransferase 1-6	0	1	0	1
Potassium-transporting ATPase alpha chain 1	0	1	0	1
Bombesin receptor subtype-3	0	0	1	1
UDP-glucuronosyltransferase 2B10	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-2	0	3	0	4
Potassium-transporting ATPase subunit beta	0	1	0	1
Potassium-transporting ATPase alpha chain 2	0	0	0	1
Sodium/potassium-transporting ATPase subunit beta-3	0	2	0	3
Sodium/potassium-transporting ATPase subunit gamma	0	2	0	3
WD repeat-containing protein 5	0	1	0	1
Glutathione S-transferase omega-1	0	2	0	2
Histone-lysine N-methyltransferase 2A	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	2	0	3
Cytosolic endo-beta-N-acetylglucosaminidase	0	1	0	1
Phosphatidylserine lipase ABHD16A	0	1	0	1
Pancreatic triacylglycerol lipase	0	4	0	5
Lipoprotein lipase	0	1	0	1
Hepatic triacylglycerol lipase	0	1	0	1
Pancreatic triacylglycerol lipase	0	1	0	1
Kappa-type opioid receptor	0	1	0	1
Platelet-activating factor acetylhydrolase	0	1	0	1
Neutral cholesterol ester hydrolase 1	0	1	0	1
Diacylglycerol lipase-alpha	0	1	0	1
Lysophosphatidylserine lipase ABHD12	0	1	0	1
Diacylglycerol lipase-beta	0	1	0	1
Monoacylglycerol lipase ABHD6	0	1	0	1
Acyl-protein thioesterase 2	0	1	0	1
Endothelial lipase	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	2	0	2
Cytochrome P450 11B2, mitochondrial	0	1	0	1
Cytochrome P450 11B2, mitochondrial	0	1	0	1
Chain H, Igg2b-kappa 40-50 Fab (heavy Chain)	0	1	0	1
Chain L, Igg2b-kappa 40-50 Fab (light Chain)	0	1	0	1
Chain A, Na, K-ATPase alpha subunit	0	0	1	1
STAT3, partial	0	1	0	1
Kruppel-like factor 5	0	1	0	1
signal transducer and activator of transcription 1-alpha/beta isoform alpha	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-2	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	2
MBT domain-containing protein 1	0	1	0	1
Lethal(3)malignant brain tumor-like protein 4	0	1	0	1
Lethal(3)malignant brain tumor-like protein 3	0	1	0	1
Lethal(3)malignant brain tumor-like protein 1	0	1	0	1
Solute carrier family 22 member 8	0	1	0	2
Amine oxidase [flavin-containing] A	0	2	1	3
Amine oxidase [flavin-containing] B	0	3	1	5
Pyrroline-5-carboxylate reductase 1, mitochondrial	0	1	0	1
Renin	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
vasopressin V1b receptor	1	0	0	1
relaxin receptor 1 isoform 1	1	0	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	2	0	2
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	1	0	1
Tumor necrosis factor	0	1	0	1
Chitotriosidase-1	0	3	1	4
Endochitinase B1	0	3	1	4
Alpha-1B adrenergic receptor	0	3	0	3
Estrogen receptor 1	0	1	0	1
fMet-Leu-Phe receptor	0	1	0	1
Prostaglandin G/H synthase 2	0	2	0	2
Prostaglandin G/H synthase 1	0	2	0	2
Cyclooxygenase-2	0	1	0	1
interferon gamma precursor	0	0	0	2
Beta-casein	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Alpha-mannosidase 2C1	0	0	1	1
Bromodomain-containing protein 2	0	2	0	2
Alpha-2B adrenergic receptor	0	2	0	2
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	1	0	1
Alpha-2C adrenergic receptor	0	2	0	2
Alpha-2A adrenergic receptor	0	2	0	2
Alpha-2A adrenergic receptor	0	1	0	1
Multidrug and toxin extrusion protein 2	0	1	0	1
luciferase	0	0	0	1
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Glutamine synthetase	0	0	1	1
Nociceptin receptor	0	0	1	1
Neuromedin-K receptor	0	0	1	1
Cholecystokinin receptor type A	0	1	1	2
Nuclear receptor subfamily 2 group E member 1	0	0	2	2
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, APH(2')-Id	0	1	0	1
glucose-6-phosphate dehydrogenase	0	1	0	1
DNA polymerase III, partial	1	0	0	1
Neuraminidase	0	4	0	4
hexokinase	0	2	0	2
galactokinase	1	0	0	1
tyrosine-protein kinase Yes	1	0	0	1
Maltase-glucoamylase, intestinal	0	1	0	1
NUAK family SNF1-like kinase 1	0	1	0	1
Lysine-specific histone demethylase 1A	0	2	0	2
G2/mitotic-specific cyclin-B2	0	1	0	1
Arginase	0	1	0	1
Prothrombin	0	1	0	1
Chymotrypsin-like elastase family member 1	0	1	0	1
Protein E6	0	1	0	1
Neuraminidase	0	1	0	1
Phospholipase A2	0	1	0	1
Beta-lactamase	0	2	0	2
Glycogen phosphorylase, liver form	0	1	0	1
Epoxide hydrolase 1	0	1	0	1
Tyrosine-protein kinase Yes	0	1	0	1
Proto-oncogene tyrosine-protein kinase receptor Ret	0	1	0	1
Insulin-like growth factor 1 receptor	0	1	0	1
72 kDa type IV collagenase	0	1	0	1
Stromelysin-1	0	1	0	1
Hepatocyte growth factor receptor	0	1	0	1
Heterogeneous nuclear ribonucleoprotein A1	0	0	1	1
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	0	1	0	1
Alpha-amylase 1A	0	1	0	1
Lysosomal alpha-glucosidase	0	1	0	1
Sialidase	0	2	0	2
Malate dehydrogenase	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 2	0	1	0	1
Cyclin-dependent kinase 4	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Cystic fibrosis transmembrane conductance regulator	0	0	3	3
Sucrase-isomaltase, intestinal	0	1	0	1
G2/mitotic-specific cyclin-B1	0	1	0	1
Urease subunit alpha	0	3	0	3
Serine/threonine-protein kinase B-raf	0	1	0	1
G2/mitotic-specific cyclin-B	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Chymotrypsinogen B	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX12	0	1	0	1
Glycogen synthase kinase-3 beta	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 4	0	1	0	1
Casein kinase II subunit alpha'	0	2	0	2
Amine oxidase [flavin-containing] A	0	1	0	1
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	2	0	2
G1/S-specific cyclin-D1	0	1	0	1
C-X-C chemokine receptor type 1	0	1	0	1
Phosphatidylinositol 3-kinase regulatory subunit alpha	0	1	0	1
Cytosol aminopeptidase	0	1	0	1
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	0	1	0	1
Tyrosine-protein kinase receptor UFO	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
RAC-alpha serine/threonine-protein kinase	0	1	0	1
Bifunctional epoxide hydrolase 2	0	3	0	3
Vascular endothelial growth factor receptor 2	0	1	0	1
Receptor-type tyrosine-protein kinase FLT3	0	1	0	1
17-beta-hydroxysteroid dehydrogenase type 2	0	1	0	1
Macrophage metalloelastase	0	1	0	1
Glutathione reductase	0	1	0	1
Tyrosine-protein kinase SYK	0	1	1	2
1-deoxy-D-xylulose 5-phosphate reductoisomerase	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	2	0	2
Prolyl endopeptidase	0	2	0	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	2	0	2
Glycogen synthase kinase-3 alpha	0	1	0	1
Glycogen synthase kinase-3 beta	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
C-C chemokine receptor type 4	0	1	0	1
Serine/threonine-protein kinase Nek2	0	1	0	1
Oligo-1,6-glucosidase IMA1	0	1	0	1
Serine/threonine-protein kinase PLK1	0	1	0	1
Death-associated protein kinase 1	0	1	0	1
Mitogen-activated protein kinase 10	0	2	0	2
Amine oxidase [flavin-containing] B	0	1	0	1
Beta-secretase 1	0	2	1	3
Anthrax toxin receptor 2	0	1	0	1
Casein kinase II subunit beta	0	2	0	2
Casein kinase II subunit alpha	0	2	0	2
Urease subunit beta	0	3	0	3
Aldo-keto reductase family 1 member B1	0	1	0	1
Cyclin-dependent kinase 6	0	1	0	1
Cyclin-dependent-like kinase 5	0	1	0	1
Heat shock factor protein 1	0	1	0	1
Sorbitol dehydrogenase	0	1	0	1
Cyclin homolog	0	1	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Dual specificity mitogen-activated protein kinase kinase 1	0	1	0	1
Lactoylglutathione lyase	0	2	0	2
Focal adhesion kinase 1	0	1	0	1
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	1	0	1
ELAV-like protein 3	0	1	0	1
Cyclin-dependent kinase 5 activator 1	0	1	0	1
ELAV-like protein 1	0	1	0	1
Serine/threonine-protein kinase N1	0	1	0	1
Probable maltase-glucoamylase 2	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Substance-K receptor	0	2	0	2
Integrase	0	1	0	1
Casein kinase II subunit alpha 3	0	2	0	2
Inositol polyphosphate multikinase	0	1	0	1
G2/mitotic-specific cyclin-B3	0	1	0	1
Aldo-keto reductase family 1 member C21	0	2	0	2
Enoyl-acyl-carrier protein reductase	0	2	0	2
3-oxoacyl-acyl-carrier protein reductase	0	1	0	1
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)	0	1	0	1
Chymotrypsin-C	0	1	0	1
Cyclin-dependent kinase 1	0	1	0	1
Phosphodiesterase	0	1	0	1
G-protein coupled receptor 35	0	1	1	2
Serine/threonine-protein kinase Nek6	0	1	0	1
NADPH oxidase 4	0	1	0	1
Dipeptidyl peptidase 3	0	1	0	1
Inositol hexakisphosphate kinase 2	0	1	0	1
Short transient receptor potential channel 5	0	1	0	1
ALK tyrosine kinase receptor	0	1	0	1
Sialidase-2	0	1	0	1
Golgi-associated PDZ and coiled-coil motif-containing protein isoform b	0	0	0	1
DNA dC->dU-editing enzyme APOBEC-3F isoform a	3	0	0	3
nuclear factor NF-kappa-B p105 subunit isoform 1	1	0	0	1
Chromaffin granule amine transporter	0	1	0	1
Synaptic vesicular amine transporter	0	1	0	1
Synaptic vesicular amine transporter	0	2	1	3
Synaptic vesicular amine transporter	0	1	0	1
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR	0	0	1	1
Retinol-binding protein 4	0	0	1	1
Beta-lactoglobulin	0	0	1	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
NH(3)-dependent NAD(+) synthetase	0	1	0	1
Arylacetamide deacetylase	0	1	0	2
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Genome polyprotein	0	1	0	1
Neuraminidase	0	1	0	1
Dihydroorotate dehydrogenase	0	1	0	1
Neuromedin-U receptor 2	0	0	2	2
Chain A, Mineralocorticoid receptor	0	1	0	1
Chain A, Mineralocorticoid receptor	0	1	0	1
Prolyl 4-hydroxylase, beta polypeptide	0	0	0	1
interleukin-8 isoform 1 precursor	0	1	0	1
Monocarboxylate transporter 4	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	1	0	1
Peroxisome proliferator-activated receptor alpha	0	0	1	1
Peroxisome proliferator-activated receptor delta	0	0	1	1
Peroxisome proliferator-activated receptor gamma	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	0	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	0	0	1
Glucose-6-phosphate 1-dehydrogenase	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	0	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Chain A, Pyridoxal kinase	0	1	0	1
Chain A, Pyridoxal Kinase	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Thyroid hormone receptor beta	0	1	0	1
Adenosine receptor A1	0	2	0	2
Vasopressin V2 receptor	0	0	0	1
Adenosine receptor A2a	0	1	0	1
Adenosine receptor A1	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Adenylate cyclase type 1	0	0	0	1
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	0	1	0	1
Adenosine receptor A2b	0	0	0	1
Phospholipase A-2-activating protein	0	1	0	1
Ubiquitin-like modifier activating enzyme 2	0	1	0	1
SUMO1 activating enzyme subunit 1	0	1	0	1
SUMO-conjugating enzyme UBC9	0	1	0	1
eukaryotic translation initiation factor 4 gamma 1 isoform 4	0	1	0	1
eukaryotic translation initiation factor 4E isoform 1	0	1	0	1
Vif	0	1	0	1
Tat	0	1	0	1
bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase	0	1	0	1
Thymidine kinase	0	1	0	2
Thymidine kinase	0	1	0	2
Thymidine phosphorylase	0	0	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase, cytosolic	0	0	0	2
Thymidine kinase	0	0	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase	0	1	0	2
Thymidine kinase	0	0	0	1
Thymidine kinase	0	0	0	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Thyroid hormone receptor alpha	0	0	1	1
Thyroid hormone receptor beta	0	0	1	1
Proliferating cell nuclear antigen	0	1	0	1
Retinoic acid receptor RXR-alpha	0	2	4	6
Malate dehydrogenase, mitochondrial	0	1	0	1
Monocarboxylate transporter 8	0	0	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
Tyrosine-protein phosphatase non-receptor type 2	0	1	0	1
M-phase inducer phosphatase 2	0	1	0	1
Chain A, Nuclear Receptor ROR-beta	0	1	0	1
Ornithine decarboxylase	0	0	0	1
Retinoic acid receptor alpha	0	2	2	7
Retinoic acid receptor beta	0	2	2	7
Retinoic acid receptor alpha	0	1	2	3
Retinoic acid receptor gamma	0	2	2	7
Retinoic acid receptor gamma	0	1	2	3
Retinoic acid receptor beta	0	1	2	3
Cellular retinoic acid-binding protein 2	0	0	1	1
Retinoic acid receptor RXR-alpha	0	1	2	3
Retinoic acid receptor RXR-beta	0	2	2	4
Retinoic acid receptor RXR-beta	0	1	2	3
Retinoic acid receptor RXR-gamma	0	1	2	3
Nuclear receptor ROR-alpha	0	1	0	1
Cellular retinoic acid-binding protein 1	0	1	0	2
Retinoic acid receptor RXR-gamma	0	2	2	4
Cellular retinoic acid-binding protein 1	0	0	1	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	2	1	3
Nuclear receptor ROR-beta	0	1	0	1
guanine nucleotide-binding protein subunit alpha-15	0	1	1	2
D(3) dopamine receptor isoform e	1	0	0	1
trace amine-associated receptor 1	0	1	1	2
Phenylethanolamine N-methyltransferase	0	1	0	1
Dopamine beta-hydroxylase	0	0	0	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
SLC16A10 protein	0	0	0	1
Monocarboxylate transporter 10	0	0	0	1
Coagulation factor XIII A chain	0	1	0	1
Fatty-acid amide hydrolase 2	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
Chain A, Arginase 1	0	1	0	1
Transcription intermediary factor 1-alpha	0	1	0	1
DNA-dependent protein kinase catalytic subunit	0	1	0	1
E3 ubiquitin-protein ligase TRIM33	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research Excerpts

Overview

Context

Treatment

Research

Studies (840)

Protein Targets (1,767)

Hypertension, Essential

Synonyms(1)

Research Excerpts

Overview

Context

Treatment

Research

Studies (840)

Drugs Studied (334)

Protein Targets (1,767)