| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| hypoxia-inducible factor 1 alpha subunit | 4 | 0 | 0 | 4 |
| RAR-related orphan receptor gamma | 6 | 0 | 0 | 6 |
| GLI family zinc finger 3 | 7 | 0 | 0 | 7 |
| AR protein | 8 | 0 | 0 | 8 |
| aldehyde dehydrogenase 1 family, member A1 | 6 | 0 | 0 | 6 |
| retinoic acid nuclear receptor alpha variant 1 | 5 | 0 | 0 | 5 |
| retinoid X nuclear receptor alpha | 3 | 0 | 0 | 3 |
| estrogen nuclear receptor alpha | 7 | 0 | 0 | 7 |
| peroxisome proliferator-activated receptor delta | 2 | 0 | 0 | 2 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 5 | 0 | 0 | 5 |
| activating transcription factor 6 | 4 | 0 | 0 | 4 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | 5 | 0 | 0 | 5 |
| Histone H2A.x | 5 | 0 | 0 | 5 |
| thyroid hormone receptor beta isoform a | 2 | 0 | 0 | 2 |
| heat shock protein beta-1 | 2 | 0 | 0 | 2 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 6 | 0 | 0 | 6 |
| lamin isoform A-delta10 | 2 | 0 | 0 | 2 |
| Voltage-dependent calcium channel gamma-2 subunit | 4 | 0 | 0 | 4 |
| Glutamate receptor 2 | 4 | 0 | 0 | 4 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | 2 | 0 | 0 | 2 |
| Luciferase | 2 | 0 | 0 | 2 |
| USP1 protein, partial | 4 | 0 | 0 | 4 |
| TDP1 protein | 4 | 0 | 0 | 4 |
| Microtubule-associated protein tau | 4 | 0 | 0 | 4 |
| glucocorticoid receptor [Homo sapiens] | 5 | 0 | 0 | 5 |
| peroxisome proliferator activated receptor gamma | 3 | 0 | 0 | 3 |
| euchromatic histone-lysine N-methyltransferase 2 | 6 | 0 | 0 | 6 |
| vitamin D3 receptor isoform VDRA | 4 | 0 | 0 | 4 |
| thyroid hormone receptor beta isoform 2 | 4 | 0 | 0 | 4 |
| flap endonuclease 1 | 3 | 0 | 0 | 3 |
| serine/threonine-protein kinase PLK1 | 2 | 0 | 0 | 2 |
| eyes absent homolog 2 isoform a | 1 | 0 | 0 | 1 |
| DNA polymerase eta isoform 1 | 2 | 0 | 0 | 2 |
| geminin | 6 | 0 | 0 | 6 |
| peripheral myelin protein 22 | 3 | 0 | 0 | 3 |
| survival motor neuron protein isoform d | 1 | 0 | 0 | 1 |
| histone acetyltransferase KAT2A isoform 1 | 2 | 0 | 0 | 2 |
| ATP-binding cassette sub-family C member 3 | 0 | 3 | 0 | 3 |
| Multidrug resistance-associated protein 4 | 0 | 3 | 0 | 3 |
| Bile salt export pump | 0 | 2 | 0 | 2 |
| Bile salt export pump | 0 | 5 | 0 | 5 |
| Rap guanine nucleotide exchange factor 3 | 3 | 0 | 0 | 3 |
| Cellular tumor antigen p53 | 6 | 0 | 0 | 6 |
| Rap guanine nucleotide exchange factor 4 | 1 | 0 | 0 | 1 |
| thyroid stimulating hormone receptor | 1 | 0 | 0 | 1 |
| regulator of G-protein signaling 4 | 2 | 0 | 0 | 2 |
| cytochrome P450 2D6 isoform 1 | 1 | 0 | 0 | 1 |
| cytochrome P450 2C9 precursor | 2 | 0 | 0 | 2 |
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | 3 | 0 | 0 | 3 |
| nuclear receptor ROR-gamma isoform 1 | 2 | 0 | 0 | 2 |
| cytochrome P450 3A4 isoform 1 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit pi | 2 | 0 | 0 | 2 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | 2 | 0 | 0 | 2 |
| 5-hydroxytryptamine receptor 1A | 0 | 2 | 1 | 3 |
| D(2) dopamine receptor | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 2A | 0 | 3 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit delta | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 2 | 0 | 0 | 2 |
| 5-hydroxytryptamine receptor 2A | 0 | 3 | 1 | 6 |
| 5-hydroxytryptamine receptor 2C | 0 | 3 | 0 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 2 | 0 | 0 | 2 |
| Alpha-1A adrenergic receptor | 0 | 3 | 1 | 4 |
| Histamine H2 receptor | 3 | 0 | 0 | 4 |
| D(2) dopamine receptor | 0 | 3 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 2 | 0 | 0 | 2 |
| GABA theta subunit | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit epsilon | 2 | 0 | 0 | 2 |
| acetylcholinesterase | 2 | 0 | 0 | 2 |
| estrogen receptor 2 (ER beta) | 3 | 0 | 0 | 3 |
| nuclear receptor subfamily 1, group I, member 3 | 4 | 0 | 0 | 4 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 4 | 0 | 0 | 4 |
| estrogen-related nuclear receptor alpha | 5 | 0 | 0 | 5 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | 5 | 0 | 0 | 5 |
| aryl hydrocarbon receptor | 3 | 0 | 0 | 3 |
| thyroid stimulating hormone receptor | 2 | 0 | 0 | 2 |
| B2 bradykinin receptor | 0 | 1 | 0 | 1 |
| Dihydrofolate reductase | 0 | 0 | 0 | 1 |
| Dihydrofolate reductase | 0 | 1 | 0 | 1 |
| Chymotrypsinogen A | 0 | 0 | 0 | 1 |
| Beta-lactamase | 0 | 1 | 0 | 1 |
| Amyloid-beta precursor protein | 0 | 3 | 0 | 3 |
| Beta-lactamase | 0 | 0 | 0 | 1 |
| Beta-galactosidase | 0 | 1 | 0 | 2 |
| 5-hydroxytryptamine receptor 1A | 0 | 2 | 0 | 2 |
| Choline O-acetyltransferase | 0 | 1 | 0 | 1 |
| Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | 0 | 2 | 0 | 2 |
| PH domain leucine-rich repeat-containing protein phosphatase 2 | 0 | 1 | 0 | 1 |
| Chymotrypsin-C | 0 | 1 | 0 | 1 |
| IDH1 | 1 | 0 | 0 | 1 |
| Deoxycytidine kinase | 0 | 0 | 0 | 1 |
| Cereblon isoform 4 | 0 | 2 | 0 | 2 |
| Insulin-like growth factor-binding protein 5 | 0 | 0 | 1 | 1 |
| Choline O-acetyltransferase | 0 | 1 | 0 | 1 |
| Protein cereblon | 0 | 2 | 0 | 2 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | 3 | 0 | 0 | 3 |
| progesterone receptor | 3 | 0 | 0 | 3 |
| Eyes absent homolog 2 | 0 | 1 | 0 | 1 |
| Angiotensin-converting enzyme | 0 | 1 | 0 | 1 |
| Metallo-beta-lactamase VIM-13 | 0 | 1 | 0 | 1 |
| Beta-lactamase | 0 | 1 | 0 | 1 |
| Beta-lactamase | 0 | 1 | 0 | 1 |
| Beta-lactamase VIM-1 | 0 | 1 | 0 | 1 |
| SMAD family member 2 | 3 | 0 | 0 | 3 |
| SMAD family member 3 | 3 | 0 | 0 | 3 |
| farnesoid X nuclear receptor | 2 | 0 | 0 | 2 |
| pregnane X nuclear receptor | 3 | 0 | 0 | 3 |
| G | 2 | 0 | 0 | 2 |
| cytochrome P450 2D6 | 3 | 0 | 0 | 3 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | 1 | 0 | 0 | 1 |
| Interferon beta | 2 | 0 | 0 | 2 |
| HLA class I histocompatibility antigen, B alpha chain | 2 | 0 | 0 | 2 |
| Inositol hexakisphosphate kinase 1 | 2 | 0 | 0 | 2 |
| Canalicular multispecific organic anion transporter 1 | 0 | 2 | 0 | 2 |
| cytochrome P450 2C9, partial | 2 | 0 | 0 | 2 |
| Purine nucleoside phosphorylase | 0 | 2 | 0 | 2 |
| Hypoxanthine-guanine phosphoribosyltransferase | 0 | 0 | 0 | 1 |
| Ricin | 0 | 1 | 0 | 1 |
| 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase | 0 | 0 | 1 | 1 |
| Purine nucleoside phosphorylase | 0 | 0 | 1 | 2 |
| Shiga toxin subunit A | 0 | 1 | 0 | 1 |
| Guanine deaminase | 0 | 0 | 0 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 4 | 0 | 0 | 4 |
| dopamine D1 receptor | 1 | 0 | 0 | 1 |
| EWS/FLI fusion protein | 2 | 0 | 0 | 2 |
| cytochrome P450 2C19 precursor | 1 | 0 | 0 | 1 |
| D(1A) dopamine receptor | 1 | 0 | 0 | 1 |
| chromobox protein homolog 1 | 2 | 0 | 0 | 2 |
| potassium voltage-gated channel subfamily H member 2 isoform d | 1 | 0 | 0 | 1 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | 2 | 0 | 0 | 2 |
| 5-hydroxytryptamine receptor 2C | 0 | 2 | 1 | 3 |
| Alpha-1B adrenergic receptor | 0 | 1 | 1 | 2 |
| D | 0 | 1 | 0 | 1 |
| D(4) dopamine receptor | 0 | 1 | 0 | 1 |
| Alpha-1D adrenergic receptor | 0 | 1 | 1 | 2 |
| Sodium-dependent noradrenaline transporter | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 1D | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 1B | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 1B | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 2B | 0 | 2 | 1 | 3 |
| Histamine H1 receptor | 0 | 1 | 0 | 1 |
| Sodium-dependent serotonin transporter | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 7 | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 7 | 0 | 1 | 0 | 1 |
| Histamine H1 receptor | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 2B | 0 | 2 | 0 | 3 |
| 5-hydroxytryptamine receptor 5A | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 6 | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 7 | 0 | 1 | 0 | 1 |
| Spike glycoprotein | 2 | 0 | 0 | 2 |
| Synaptic vesicular amine transporter | 0 | 2 | 0 | 2 |
| Vesicular acetylcholine transporter | 0 | 1 | 0 | 1 |
| Sigma non-opioid intracellular receptor 1 | 0 | 1 | 0 | 1 |
| ATP-dependent phosphofructokinase | 1 | 0 | 0 | 1 |
| Chain A, Beta-lactamase | 1 | 0 | 0 | 1 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | 2 | 0 | 0 | 2 |
| Chain A, 2-oxoglutarate Oxygenase | 1 | 0 | 0 | 1 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | 1 | 0 | 0 | 1 |
| thioredoxin reductase | 1 | 0 | 0 | 1 |
| WRN | 1 | 0 | 0 | 1 |
| phosphopantetheinyl transferase | 2 | 0 | 0 | 2 |
| GLS protein | 1 | 0 | 0 | 1 |
| Valosin-containing protein | 0 | 1 | 0 | 1 |
| thioredoxin glutathione reductase | 2 | 0 | 0 | 2 |
| apical membrane antigen 1, AMA1 | 1 | 0 | 0 | 1 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 2 | 0 | 0 | 2 |
| bromodomain adjacent to zinc finger domain 2B | 1 | 0 | 0 | 1 |
| lysosomal alpha-glucosidase preproprotein | 1 | 0 | 0 | 1 |
| transcriptional regulator ERG isoform 3 | 1 | 0 | 0 | 1 |
| microphthalmia-associated transcription factor isoform 9 | 0 | 1 | 0 | 1 |
| importin subunit beta-1 isoform 1 | 1 | 0 | 0 | 1 |
| DNA polymerase beta | 1 | 0 | 0 | 1 |
| ubiquitin carboxyl-terminal hydrolase 2 isoform a | 1 | 0 | 0 | 1 |
| eukaryotic translation initiation factor 4 gamma 1 isoform 4 | 0 | 1 | 0 | 1 |
| snurportin-1 | 1 | 0 | 0 | 1 |
| DNA polymerase iota isoform a (long) | 1 | 0 | 0 | 1 |
| eukaryotic translation initiation factor 4E isoform 1 | 0 | 1 | 0 | 1 |
| DNA polymerase kappa isoform 1 | 1 | 0 | 0 | 1 |
| muscleblind-like protein 1 isoform 1 | 1 | 0 | 0 | 1 |
| DNA dC->dU-editing enzyme APOBEC-3G isoform 1 | 1 | 0 | 0 | 1 |
| Neuronal acetylcholine receptor subunit alpha-4 | 1 | 0 | 0 | 1 |
| Neuronal acetylcholine receptor subunit beta-2 | 1 | 0 | 0 | 1 |
| Serum paraoxonase/arylesterase 1 | 0 | 1 | 0 | 1 |
| phosphoglycerate kinase | 1 | 0 | 0 | 1 |
| Sodium channel protein type 1 subunit alpha | 0 | 1 | 0 | 1 |
| Sodium channel protein type 2 subunit alpha | 0 | 1 | 0 | 1 |
| Sodium channel protein type 3 subunit alpha | 0 | 1 | 0 | 1 |
| Vasopressin V2 receptor | 0 | 1 | 1 | 2 |
| Oxytocin receptor | 0 | 2 | 2 | 4 |
| Vasopressin V1a receptor | 0 | 1 | 0 | 1 |
| Vasopressin V1a receptor | 0 | 2 | 1 | 3 |
| Vasopressin V1b receptor | 0 | 1 | 1 | 2 |
| Vasopressin V1b receptor | 0 | 1 | 0 | 1 |
| Oxytocin receptor | 0 | 1 | 0 | 1 |
| Oxytocin receptor | 0 | 0 | 1 | 1 |
| Vasopressin V2 receptor | 0 | 1 | 0 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | 0 | 1 | 0 | 1 |
| Cystathionine gamma-lyase | 0 | 1 | 0 | 1 |
| Succinyl-diaminopimelate desuccinylase | 0 | 1 | 0 | 1 |
| Solute carrier organic anion transporter family member 1A4 | 0 | 0 | 0 | 1 |
| Solute carrier family 22 member 6 | 0 | 1 | 0 | 1 |
| Solute carrier organic anion transporter family member 2B1 | 0 | 2 | 0 | 3 |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 0 | 1 | 0 | 1 |
| Insulin receptor | 0 | 1 | 0 | 1 |
| Prostaglandin G/H synthase 2 | 0 | 1 | 0 | 1 |
| Solute carrier organic anion transporter family member 1A1 | 0 | 0 | 0 | 1 |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 0 | 1 | 0 | 1 |
| Solute carrier family 22 member 6 | 0 | 1 | 0 | 1 |
| Solute carrier family 22 member 7 | 0 | 1 | 0 | 1 |
| Canalicular multispecific organic anion transporter 1 | 0 | 1 | 0 | 2 |
| Solute carrier family 22 member 8 | 0 | 1 | 0 | 1 |
| Solute carrier organic anion transporter family member 1B3 | 0 | 2 | 0 | 2 |
| Solute carrier family 22 member 11 | 0 | 1 | 0 | 1 |
| Solute carrier family 22 member 8 | 0 | 1 | 0 | 2 |
| Solute carrier family 22 member 7 | 0 | 1 | 0 | 1 |
| Solute carrier organic anion transporter family member 1B1 | 0 | 2 | 0 | 3 |
| Chain A, HADH2 protein | 1 | 0 | 0 | 1 |
| Chain B, HADH2 protein | 1 | 0 | 0 | 1 |
| pregnane X receptor | 1 | 0 | 0 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | 1 | 0 | 0 | 1 |
| Glucocorticoid receptor | 0 | 2 | 1 | 3 |
| Glycine receptor subunit alpha-1 | 0 | 2 | 0 | 2 |
| Glycine receptor subunit beta | 0 | 2 | 0 | 2 |
| Glycine receptor subunit alpha-2 | 0 | 2 | 0 | 2 |
| Glycine receptor subunit alpha-3 | 0 | 2 | 0 | 2 |
| Nuclear receptor ROR-gamma | 1 | 0 | 0 | 1 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |